I've lost folks to cancer. They cannot be replaced. One in two of us will be diagnosed with it in our lifetime. Let's find a different end to this story.
Building
@jori_health
Jori is a vendor neutral population-scale health information infrastructure. It is a decentralized,
@_kylepeters
How random. I once nerded out (for days) researching this topic. If you zoom wayy into your iron griddle’s cooking surface, you’ll see lots of tiny micro-imperfections. The sacrificial pancake seasons these imperfections - sticky spots are precisely the zones that needed
Why is EPIC so hard to topple?
Doctors & nurses hate it. Yet, nobody has managed to dethrone Epic. Far too many new-entrants have tried and gotten nowhere. Why?
For months, I’ve had in-depth convos with folks at all levels at a hospital. Notes from 100s of hours of convos 🧵
"Asking 'What problems do blockchains solve? is like asking 'What problems does steel solve over, say, wood?'
You can make a building or railway out of either.
But steel gave us taller buildings, stronger railways, and more ambitious public works at the outset of the
If you are in need of high-fidelity oncology data-sets, we're releasing an open-source synthetic data-set builder.
Data is nowhere to be found. Even synthetic data-sets cost $5-$15k (or more). Let's end this.
If you need specific things in this dataset, happy to oblige.
This stuff can save years of heartache & wasted effort.
There is such little literature on this topic that is clear, well articulated, and actionable.
To do this and give it away for free is just great service to yearning founders. Spent hours last night. Thank you
@lennysan
Todd Jackson (
@tjack
) was VP of Product and Design at
@Dropbox
, Director of Product at
@Twitter
, Product Lead for
@Gmail
, PM for
@Facebook
's Newsfeed, Photos, and Groups, and also the founder of Cover (which he sold to Twitter).
Today, Todd is a partner at
@FirstRound
Capital,
Oncologists are heroes without a cape.
We’re doing open office hours for 50 oncologists at
@Jori_health
. Help you with AI, ML, and Data Science for free.
Send us a note to get started hello
@jori
.health
Oncologists: we want to teach you AI, ML, & Data Science for FREE. Why? Because we are good at it and we want to help you fight cancer. Want to help 50 oncologists.
Sign up for 1:1 office hours (email: hello
@jori
.health). First come, first serve. After we learn what you need, we
I had to pay $10 in cash & all I had was a $20. Vendor had no change. We both agreed that tearing a $20 neatly in half does not count. In a parallel universe, that should work.
Floored to be in the presence of the Ellis Islands Medals of Honors recipients last night
@DrOz
set the event on fire as the MC.
EIHS honors the contributions made by immigrants and their descendants throughout American history.
At this point, I'm fully convinced that crispy writing is the one skill that can pull you higher in any field.
Check out these two emails I got for a marketing role at
@vimcal
— one from a director and the other from a 16-yr old kid.
Who would you rather take a chance on?
If you are in need of high-fidelity oncology data-sets, we're releasing an open-source synthetic data-set builder.
Data is nowhere to be found. Even synthetic data-sets cost $5-$15k (or more). Let's end this.
In the next several months, this open-source model will evolve
Cancer data is nowhere to be found. Not even synthetic data.
When we started work on decentralizing massive troves of oncology data, we just wanted awesome datasets to experiment with. Soon, we found vendors who quoted $10k - for FAKE data 😡
We bet there are many who struggle
NEW VIDEO - Rabbit R1: Barely Reviewable
This is the pinnacle of a trend that's been annoying for years: Delivering barely finished products to win a "race" and then continuing to build them after charging full price. Games, phones, cars, now AI in a box
5/ Not all heroes wear capes
Oncologists are heroes.
If you are an oncologist, send in a DM or email (hello
@jori
.health). We have open office hours every week. Want to help literally as many of you with data, AI, ML & DeSci to help propel your careers.
Plus, we're rolling our
@AdamFard_
Stand on top of a mountain. Tell the world what you are about to do and dare them to come stop you. If they steal that idea and actually spend the next 10-15 years of their lives doing better that you, with all the pain, toil, heartache & joy - they deserve it.
Every time I encounter precision and recall I need to brush up their definitions for forgetting them the next day 😭. If that’s true for you as well, say no more 🥳!
In today’s lecture, we finally understand *visually* how to evaluate a binary classifier! 😇😇😇
Computer science is not science.
Data science is not science.
Master of science in CS = you did NOT master science.
And political science is most definitely not science.
AI in healthcare will be the largest mover.
A lot of movement in healthcare x AI right now are to automate admin tasks, including transcribing doctor/patient interactions. Barrier to entry is low.
The big wins will happen when AI moves upstream to diagnosis & preventive care.
Convo last night: Why can AI make these videos and not read radiology scans etc?
AI can crush radiology scans and most healthcare applications, harder part is entrepreneurs breaking down huge barriers of healthcare ecosystem to deploy.
All the below + founder has X account with very few followers.
I’ve met some truly incredible people on here who are literally “nobodies” if you judge them by their activities on X. Turns out they’re all buried in some deep/fascinating stuff.
How to spot a company that’s starting a new hype cycle instead of chasing an old one…
1. You wouldn’t describe the company as “the Uber for x” or “the Tinder for y.” A first-of-its-kind company can’t be categorized neatly in comparison to an existing company.
2. The founder is
4/ Jori secures healthcare infra & bolsters compliance
Data breaches, hacks, and ransomware attacks are a near constant in healthcare. Most never get reported.
Hackers love health data because it is FAR more valuable than any other. Centralized storage is the enabler.
Had dinner with a friend last night who is a scientist & does a lot of medical research.
Biggest trend her team has been tracking lately?
Average age of cancer onset for various types is getting lower. Some used to be >55 and are now <40.
Massive uptick in colorectal cancers.
2/ What is Jori?
Jori is a single source-of-truth for oncology-data. Think of it as a giant oracle of everything related to oncology — only that this oracle is decentralized (i.e., entirely owned & monetized by the people).
Our health records are scattered, inoperable,
A recent study reported that patients WANT to share their data for medical research. But.. despite the desire to do so, this data is nowhere to be found.
Between 2016-21, no less than 40 health-tech startups went the “consumer” route urging patients to upload health data onto
Airbnb is dying.
Greed. Outrageous fees. Inconsistency. With RWA tokenization looming in the horizon, Airbnb/Sonder etc., will soon be brilliant ideas of a bygone era. Why? Because the very idea of paying inflated rents needs to just stop.
Thread 🧵
3/ Jori accelerates AI research in oncology
Stuff that used to take days now happens in minutes.
Jori propels research, reporting, and scientific breakthroughs in oncology by making population-scale data available for AI querying & model training. Better healthcare requires
Going to school is an achievement.
But do not mistake it for building. Folks who are merely “interested” will get to watch *obsessed* people change the world.
You log onto X, you see a really cool post, and just when you’re about to click on it…
.. it freaking scrolls WAY up and you CANT find that awesome post anymore.
Every freaking time.
@snowmaker
41% is very high. This could mean a few things:
(a) nepotism & in-breeding that’s not necessarily bad. Perhaps there is a culture of excellence that grows the network powerfully while maintaining a strong core.
(b) however, whether this nepotism is a net positive to innovation
6/ The movies brought the cinema home. The Internet brought the work home. Covid made us realize we can do better. Making people go back to office is like asking people to hand-write letters after they discovered email. It's charming. But stupid.
@tasshinfogleman
More like a moment-to-moment harmony in a permanent, irrevocable way. As in there’s no coming back. Not that I know better. But there was an enlightened monk in a monastery close to where I grew up. His very mannerism & aura was different. Can’t fake that 24x7.
What is the point of reading or writing research papers anymore? This isn't about cutting corners; it's a reflection of deeper systemic issues.
Academia attracts some of the brightest folks in the world - folks who sacrifice lucrative careers to pursue their passion. Almost
From 2016-2020, countless startups tried to deliver patient ownership of health records. None of them pulled it off.
It'll be fun to analyze them all in a future thread.
But when you look under the hood & see how health data is actually stored, you see why this is
People have NO idea how broken healthcare is until they have to advocate & legit FIGHT the system to just get basic needs for a patient covered. Sometimes I just want to give up, but every lost battle fuels my desire to change things 🥊
Strategy: Cry, lick wounds, dive back in
Let’s say you are hiking through a forest and that you are thirsty.
There is a lot of mist in the air. And you know there is a pond with fresh, clean water a mile away. What do you do?
You keep walking until you find that pond. Because you obviously can’t drink that mist.
On an average, there are 2 hacks/day on health-data. Most don’t get reported.
Providers are liable for health-data and it is a MASSIVE & needless burden on their operating budgets. Hospitals barely break even - the rare lucky ones are at a 3% margin.
At 2 hacks/day, it is only
Healthcare has come a long way. Truly has.
But somehow, it got stuck 50 years ago while the world moved on.
How much happened in 50 years, you ask? There is time, and there is "Internet" time. In 50 years:
- computers became a thing. From 1 computer every 1000 homes to 8
Robert Liston (1794-1847) was a Scottish surgeon who is most famous for amputating a patient's leg in under 2.5 minutes, operating so quickly that in the process also amputated the fingers of his assistant and slashed the coattails of a spectator, who dropped dead from sheer
hey sorry i didn’t respond to your text i’ve been trying to process my decision to commit my life’s work to an industry that has only found product market fit as a casino that requires a phd level understanding of computer science to use
To a bank, real-estate is what creates most "new" money.
"Earn money so you can pay rent/mortgage", we are told. What if we have it backwards all along? What if real-estate is money, just that we've not figured out how to tokenize it well.
The first banks were nothing but custodians of people’s money. They profited by lending to those in need using cash reserves from those who had more. At what point did these institutions end up owning almost all real-estate?
With the advent of Modern Portfolio Theory in the
Love seeing startups like
@Jori_health
bringing health data on-chain! Decentralized storage for health data is a game-changer🚀
Healthcare has a long road ahead before adopting fully decentralized solutions, but projects like Jori are paving the way to a brighter future!
#DeSci
Audio can be iffy.
Personal favorite: "Can you see my screen?". Always say no. Folks are puzzled as to why THAT did not work for (perhaps) the very first time ever.
@daveharrington
Admire the grit. But none of those people look happy. Or energetic. To dress up like THAT & show up at 4.45 is stupid. Is this a cheap attempt to evangelize office space cuz it's doing the opposite. Nobody wants to do that anymore.
We can get enough data to reach AGI, but the path will be more like curing cancer than discovering a vaccine
More below on:
- how we get data abundance for AI
- what frontier data requires
- what’s missing in evals today
Links 🔗 below of
@NoPriorsPod
w/
@saranormous
&
@eladgil
1/ Conservative & Cautious ⚠️
The decision makers at large hospitals are WAY more conservative than enterprises. Nobody is willing to risk their career by writing an 8+ figure cheque to an unproven upstart to run their critical infrastructure.
Companies earliest to this market
4/ Decision makers do NOT use it ✍🏼
People who make purchasing decisions do not care about the usability of the product. They mostly care about billing, compliance, data integrity, security, & managing costs. EMRs primarily exist for billing an insurance company or the
2/ Talk about to early to market 🕰
Healthcare was one of the earliest adopters of computing. Lockheed Martin created Eclipsys in 1971 (when nobody owned a PC). Soon after, Epic burst onto the scene in 1979.
Today, a majority of top ranked hospitals and medical schools use
7/ A well managed ship 🛳
Epic is run very efficiently. Go talk to employees at this org and they will tell you that it’s surprisingly well orchestrated despite its size.
@jjen_abel
You are so right, Jen. On the heavy hand holding front: one has to be a 'trusted consultant' to the entire team's problems: decision maker, CFO, IT/compliance, and end-user.
@gliadkovskaya
Never took a course but watching someone get really sick and going through the motions is right up there. Other than that, reading voraciously and talking to folks in health across the spectrum.
@RubiksLive
It costs time. Lazy folks will quickly point out that time is money but turns out, helping others actually creates wayyy more of it than not.
The ROI for “lending a hand” tends not just towards some larger number, but more towards infinity. Why? Because folks you help will
3/ Its clunky, its ugly, and ridden with DEBT 😢
These systems have been in place for decades. Most of these carry a lot of baggage from their development history and are too risky or brittle to modify without a compelling reason. It's the same story that most big banks find
@dabit3
Yes, crypto ecosystem needs to grow up. Its evolution will be to solve average person’s problems. Evolution, not just “revolution”. Great post.
If there is an "accelerator" that rivals Y Combinator, it is not 1 of the usual suspects
TBH, it is the Thiel Fellowship
For those unfamiliar, the Thiel Fellowship gives $100k to young people to build things (companies) instead of going to college
It differs from YC in many
Advice from Warren Buffett:
Just run your business as if:
1. You own 100% of it
2. It is the only asset in the world that you and your family have or will ever have
3. You can't sell or merge it for at least a century.
Are you interested in cancer research and artificial intelligence? Check out “Cancer AI Conversations.” These bimonthly, 1-hour virtual events will feature timely topics related to the application of
#AI
in
#CancerResearch
. Join us!
#AI4CancerResearch
After just 20 years of that, networks evolved to make web-access almost as invisible as the oxygen we breathe. In fact, no access to the web feels suffocating. Can’t think of any other technology that went invisible yet powerful/pervasive that fast.
The World Wide Web was first tested on Christmas Day in 1990.
Tim Berners-Lee and Robert Cailliau set up successful communication between a web browser & server via the Internet.
I've been spending a lot of time with some of the top surgeons & hospital CEOs in the area. We chat work, technology, and life.
They always amaze me. At a high level, most have a basic grasp of technology much better than I will ever grasp the basics of medicine or surgery.
Wonder what the Change ransomware attack means & how to thwart these in future?
We've been asked this question a bunch in the past week or so. Most of our friends at hospitals find it hard to believe this is possible. They wonder why? And most importantly, they want to know if
If my dad were alive, he’d be 97 today. I only knew him for 13 years but he left a big imprint on me.
He had this picture of Jack London hanging in his office, which is now in my son’s room.
It says: “I would rather be a superb meteor, every atom of me in magnificent glow,
“Its not because I skipped that run or workout. This is genetic. It is about mutations. It's about choices. Yet, it still feels random. Why me?”
Why does someone get Cancer?
At its core, cancer is a result of mutations in the DNA of cells. These mutations disrupt normal cell
Too many people start boring businesses to get rich, so then they can work on a more ambitious thing later. This doesn’t work. Once you’re rich, most lose that burning desire. Just do what you actually wanna do.