Mother&Wife,GI Oncology,MGH, equity,global cancer care,social justice,liquid biopsies,drug discovery, women in medicine,discovering and being your best self
Had coffee with daughter and wife of a patient who passed late 2018. This 12 year old wanted to surprise me with 3k she raised last year for
#PancreaticCancer
research . She told me she did this so other families don’t have to go through what they did
Thrilled to take on Director of the Global Cancer Care Program
@MGHCancerCenter
💯 will continue to advance care for GI onc pts but thrilled to also continue to work toward high quality cancer care globally. Thanks to
@drlouiseivers
@GlobalHealthMGH
for unending support.
much to say about today but focusing on a celebration of a legend in medicine. blessed to be a part of the
@MGHMedicine
family “raised” by this one of a kind person - the very best of humans who made us all better. Unveiling of a beautiful portrait that will be forever at
#mgh
funded!
#persistence
8 yrs post fellowship/6 in current job. Submitted 1/3 k08 3 yrs in, 2nd 3 days post partum (now almost 2 yr old) & 3rd (and last) Oct 21 @ same time as 1st discussed/not funded R01. Now K funded! “aged” a bit but helps tons re time navigating R transition!
For the skeptics, enrolled our daughter in moderna trial. could get placebo, gets multiple blood draws and ultimately could still need 2 more shots but when asked. “want to keep me, my family and friends safe. want to help!” Insights from a 7 yr old!
@mihirsparikh
@MGHMedicine
Couldn’t figure out how to edit from screen shot protecting some info. This from a meeting. disappointed to continue to see lack of understanding re impact of Covid for women
#MedTwitter
#WomenInMedicine
actively hindering participation of women. “Avoid having small children..”
Women lifting women in
#medicine
. Delayed but coming home to these from none other than
@PamelaKunzMD
when my promotion came through, brought many smiles/happy tears. Find the people that believe in you, cheer you on, have your back and nurture these wonderful relationships❤️
“Hey
@taylorswift13
”my 25 year old patient who just went on hospice is leaving the hospital tonight to see your concert — would mean the world to her if you could give her a shout out. DM me if you can!
labor of love & 1/2 ISTs when I 1st started
@MGHCancerCenter
>5 years ago. best team science w/ amazing mentors/friends/collaborators
@TedHong9
@arnavmehta3
David Ting. Signal of IO efficacy & possible biomarker for these “cold” tumors.
@NatureCancer
Slight change in
#ASCO2023
Saturday night plans. two
#gionc
spontaneously skip out on receptions and land 👇🏽and it was just incredible (and I had already gone in Boston!)
#ERAS2023
#taylorswiftchicago
will be an asco for the record books!
Thought. Submitted 1st r01 (submitting another big grant next week) while on service/have clinic, sprinkle in few talks(oh & life with 3 kids) & I’m fried. few yrs ago, I’d be 💪🏽 re productivity but realize more & more the “pride” taken for wearing ourselves out probably shameful
From the wonderful
@PamelaKunzMD
who despite all her own life stuff, sent these for a little pick me up over here. Thankful for this wonderful gi onc Wolfpack community ❤️
#ASCOiSpy
here we go!
#ASCO2022
thrilled to in my old stomping grounds in beautiful Chicago to
#ConquerCancer
together and connect with colleagues/friends, old and new across the 🌎
Not sure why many medical meetings are on weekends? It wasn’t easy for me, but took a hard re(look) at the fall (even for a few local meetings) & had to politely back out or was looking at 7 weekends of work things just in sept/Oct. actually want to do the fall soccer mom thing!
said “wife” = me. surreal few weeks being incident provider case at a major hospital. so much change in 2 wks. long way to go but thrilled to now contribute to Antibody development which will be critical! (can’t say which one!)
@mihirsparikh
contributing
So— one of my partners at work’s wife has now tested (+). She (MD) had no fever, just a dry cough, persistent over a few days.
Underscores why social distancing is so important.
We’ve made plans for most in group to stay home tomorrow. Keep as many available as poss.
will get some unpleasant messages based on comments post enrolling oldest in
#KidCove
#Moderna
trial now with littlest getting dose 1 on study. We were nervous re ?s in tiniest & effective immunity but
@mihirsparikh
and I both trust
#science
. Middle will get
#pfizer
Friday
#GI24
my favorite. Congrats to
@rachnatshroff
& team for another great year. ❤️ 🧠 full+ got training 🏃♀️ s in. Most compelling for me
#CRCSM
ipi/nivo vs chemo curves & 2yr dfs (await nivo data but a soc option). Also, look forward to more MSS localized bot/bal data
@pashtoonkasi
Tough week but then had 2 brand new Day interns
@mghmedres
@MGHMedicine
on service. magical time-watching them introduce themselves as doctor, interact w/ patients w/ the utmost empathy, take in knowledge. If only could figure out how to keep that spark alive to mitigate
#burnout
Saw 4 people just this last week under 40 with CRC. Great review on young onset
#CRC
#ColorectalCancer
complex mulitifactorial and significant area of unmet need
Excited to share our plasma only (tumor uninformed) approach to MRD in
#crcsm
as a contrast to tumor informed approaches. Can’t compare apples to apples with this limited data set but important nonetheless and sets the stage for future work
If it wasn’t already obvious as I got fired by a patient last week for needing to set some boundaries, feels more and more like medicine truly evolving into “service” industry. Here’s a review this month “excellent service” as opposed to “excellent care”
Turns out we know essentially nothing re covid immunity with these subvariants of subvariants. covid xs 3 now..March 2020, April 2022 and now July 2022. Gift that keeps on giving
Thank you
@ASCO
#ASCO20
for letting me share a piece of Rachel. so glad her dad & sister were able to watch her on the “podium” Here is her farewell video. Here’s to each and everyone of you and your good days.
My week👇🏽but🚶🏾♀️away ok. post milestone bday/Diwali feeling deeply grateful but also wondering why SO hard in medicine asking for help!🚶🏾♀️in late,pretend nbd, inpt/consults/clinic. home at midnight from tow place thinking even 30min to process/sort out logistics would’ve been nice.
Was out for our first little walk on this beautiful November day when AP called it. Oh sweet girl, tears flowing can’t wait to tell you
on the night you were born, we elected the first black and Indian woman to office. It doesn’t get much better.
@KamalaHarris
@JoeBiden
Some of the
@MGHCancerCenter
gi onc family ❤️ love these guys . Congrats to
@TedHong9
newly appointed Vice Chair of Research & Scientific Affair of Rad Onc and
@JenniferWo4
MGH program director of
#hrop
Shameless husband brag. So proud of
@mihirsparikh
At our every juncture intern, resident, fellow and now faculty (and when we were strictly quarantined for two weeks and I was isolated from COVID19 dad school) outstanding educator !
Dr. Mihir Parikh, Thoracic/IP, was selected by the BIDMC Dept of Medicine chief residents for the 2020 Non-Medical Specialties Teaching Award, which recognizes a faculty member outside the dept who contributed unselfishly to its educational activities.
@mihirsparikh
@HarvardPulm
Sent by a patient’s grieving spouse as he struggles with how people react to his loss. I’ve had too many hard conversations personally and professionally to count and still struggle to find words. Thought this was nice to share, how well intended words, can be painful.
The
@MGHCancerCenter
family continues to grieve the loss of
#josebaselga
a true giant who moved mountains for patients and our cancer center during his tenure as chief
Totally not a science talk but excited/nervous to give my dear friend , oncologist extraordinare, Rachel Pearline a voice on the
@ASCO
“podium” this weekend (a dream of hers). miss her. think of her everyday. Will share link to her farewell video post talk
@HemoncUcsf
Congrats to Dr. Aparna Parikh
@aparna1024
who was named the Director of Mass General Cancer Center's Global Cancer Care Program! She will lead the charge in continuing our goal of providing high quality cancer care globally, while still caring for her GI oncology patients.
Perhaps a 1st doing same day in and out ✈️ to opposite coast & back but well worth it! Spent day discussing
#crcsm
in a small forum conducive to great discussions
@SalemGIOncDoc
@pashtoonkasi
@SKamath_MD
optimistic
#crc
will soon truly jump on the personalized bandwagon
Local npr reached and shared brief personal story but so many more thoughts- patients Covid and non sick and dying alone, impact on non Covid patient outcomes, workforce ethics around high risk provider exposure with limited data, etc
Looking forward to co-chairing Total Health’s Evolution Boston Womens Conference Sept 24-25 2022! Leading female cancer experts sharing practice changing data. FYI give away $1K travel voucher to lucky in-person attendee.📅 Sept 24-25 2022
Register Free:
From the earliest days of my career had been in awe of women like
@CathyEngMD
who “made it” fighting essentially solo in a world of gi oncology men and now thankful this wonderful tribe!
wrapped up attending on medicine (non onc). Rusty inpt med but blast w/ remarkable
@MGHMedicine
residents. bigelow service remains one of a kind. throwback to circa 2009. thanks
@DrDanRestrepo
+co visit for💡/telling me ? ARNI/GDMT/MOCA mean. Also learned cards ❤️s entresto😂
A1: We have seen many IO fails in MSS mCRC but we are starting to see new signals (and even old data) suggesting that there may be a new “biomarker” 🔥of IO response in patients with MSS CRC
What is this biomarker?
Stay tuned.
#CRCTrialsChat
#CRCSM
@OncoAlert
Thank you
@MGHMedicine
for being my first & truest of medicine homes. From intern year to decade plus later wrapping up on the
@MGHCancerCenter
C19 surge team as responding clinician. Thanks for the tremendous support.Time to get back to full on onc mode!
The feeling post Pfizer approval when you stop what you’re doing for the unblinding call for eldest kid on the
#COVID19
5-12 moderna study & then the feeling when you hear she got the real deal
@KimberlyBlumen1
spilling your 😃 beans too. Trial for baby and now 1 kid to schedule.
Check out HR! Amazing 1L msi Chemo free option for
#crcsm
#crc
lets think re 30% of tumors that are primary progessors/falling off quickly. Who are they? anyone catch somatic vs germline breakdown? missed this (blaming catching plenary on phone/on bike ride with kids!)
#ASCO20
5 am pst virtual talk from hotel room and then a spectacular morning with
@YJanjigianMD
@AndreaCercek
@ClaireFriedma19
#diastole
after an invigorating but exhausting Jan. Looking forward to staying put in Feb but pretty great way to end the month!
marathon of Jan continues. starting inpatient and here’s another great example of
@MGH_WiO
lifting each other! Most of us lost private offices and coming up on a week inpatient, this is a pain! Friend/colleague offered hers for week. Walk in to this. great way to start❤️
A highlight of
#ASCO20
will be ASCO Voices, an unopposed session 5/30 12:15-1 w/ five 7-min talks that speak to our shared humanity, a moment of diastole amidst days of great science. Proud to welcome a diversity of voices to the stage, selected from many powerful submissions.
Sad to give up private offices. Will miss this whiteboard on a day kid came to work & stack of green papers saved of patients who passed away in pre-emr days. Went through wrote down names/messaged few families. remarkable all the people in this journey over the years
Gave grand rounds at my husbands alma matter and my disclosure after real disclosures and acknowledging
@mihirsparikh
support was that I was secretly happy to do it there before him as he was such a huge
@mtsinai
fan. Thanks for having me!
@DOMSinaiNYC
Absolutely thrilled to meet my
@ASCO
#asco2022
virtual mentoring program Thai mentees in person! Was so fun to show them the ropes at their first ever annual meeting. The future of oncology is so bright !
Oh my all the feels🥲 with my election night baby wearing her
@KamalaHarris
onesie/my pearls. Today is the last day to never have a female VP and man Amanda Gorman you are brilliant❤️
#academicgeek
the feeling you get when you submitted all the final stuff for a provisional acceptance into a high impact journal for a project that you’ve been working on for almost 5 years and 2 years since first submission that legit was helping patients!
Fact or fiction? Perhaps early post op high cfDNA levels aren’t obscuring detection as much as we thought. Congrats to rockstar friend Dr.Cohen for her great work and another ctdna guru/friend
@VanMorrisMD
for great moderating & new SOC for lonsurf/bev as we’ve often been doing
Excited to be a part of the leadership team for this global study led by
@AnwaarSaeed3
stemming from an ist she worked on. IST to global Phase 3. Congrats
@AnwaarSaeed3
and excited to be on this journey with you and hoping for another option for mss
#CRCSM
patients
A male
#MedTwitter
leader texted to ask if I thought this story hadn’t been RT’d much because it’s too shocking. In fact, it’s the opposite: sexual harassment is a routine occurrence for
#WomenInMedicine
. I don’t know Dr. Grothey in real life, but I have zero tolerance for this.
Putting to rest resection of the primary in met crc with unresectable crc. Always impressive what the Europeans can do to answer practical questions.
#crcsm
thrilled to be back in India after my recent trip but this time, oncology related! 3 city whirlwind trip with the
@karkinoshealth
Sir H.N. Reliance Foundation Hospital & Research Centre Global Townhall: Precision Oncology Jan 11th at the Taj, Mumbai certainly being a highlight!
As gi onc caring for many young onset
#CRC
remiss not to share this post by a friend. sometimes tough to get coverage at 45 for non black pts. 45 should be screening age. For younger, understand symptoms. can’t tell you the # of pts symptoms attributed to hemorrhoids, ibs, etc .
#ColonCancer
impacts us all. Even our mighty superheroes.
A reminder:
✅ No family history->screen at 45 or 50.
✅ Family history->screen at 40 or earlier.
✅ If symptoms at ANY AGE-> colonoscopy now
✅ Don’t let
#COVID19
allow u 2 delay
Wakanda Forever✊🏾
#ChadwickBoseman
As someone who has always identified as clinician 1st
#AACR21
#AACR2021
tends to bring out my
#impostersyndrome
but every yr increasingly humbled by the beautiful interplay of lab & clinic & how much learning/progress happens in the “lab” of clinic.Great Day 1. See you on Day 4.
Dr.Kunz has become a dear friend/mentor over years of serendipitous encounters and am so proud of her courage in speaking up and thrilled for her next phase as she leads the gi onc program at Yale !
After 19 years, I’ve left Stanford. The accumulated gender discrimination and harassment had taken their toll. I shared my story with
@kate_selig
and
@StanfordDaily
because I think it is important and hope it will empower others to speak up.
THREAD 1/
My everyday
#COVID19
heroes husband
@mihirsparikh
back in the MICU and sis in law shout out by Cornell dean for her 3D printing of
#PPE
in nyc.
#Workforce
#ItTakesAVillage
for now, continuing to care for my oncology patients until inevitable deployment
Proud of our team
Esp co 1st authors
@jxj1998
(now in med school)
@ASarafMD2
(new attending) for their incredible work. Started as 2017 office conversation w/
@RyanNipp
when we said let’s do this. pros matter! ctDNA data coming next
@MGHCancerCenter
We really need to start incorporating PROs into routine oncology practice, but no easy way to do this in our EMR still. This is like geriatric assessment - needs institutional champions to move it forward, guidelines not enough. Difficult to find support.
45 is indeed the new 50! Thrilled for the
#USPSTF
recs today
#CRCSM
#EarlyOnsetCRC
is a growing, global problem. Let’s get screening and figure out how to improve access for screening
45 is finally the new 50!
#ColonCancer
’s projected to be the leading cause of cancer death in folx ages 20-49 by 2040, Blacks have had the worst outcomes for many years, & this preventable disease has taken lives of many peers: I’m THANKFUL the screening age is finally age 45!🎉
Very different
#Diwali2020
this yr but from our family to yours, may the divine
#light
of
#Diwali
illuminate your home with happiness, joy, peace , hope, and health . May light always prevail over darkness. Happy Diwali!
@mihirsparikh
welcomed girl3 11:11 pm
#ElectionNight
lived/born through history w/
#COVID19
at 8 wks. We didn’t see any coverage til am. crushing reality being this close but her name means 1st rays of sun. Few more states 🙏🏽 we’ll start to see the ☀️rays
@JoeBiden
@KamalaHarris
pumpkin spice is one signal of fall as are the conference picking back up signal! missed the August
#GDUGI2022
which is personal and fan favorite. See you soon talking re
#crcsm
approaches to
#livermets
and of course
#ctDNA
🚨 And now for a new installment of Meet The Docs!
Aparna R. Parikh
@aparna1024
Pronouns: she/her/hers
Director of the
@MGHCancerCenter
Global Cancer Care Program
Tucker Gosnell Center for Gastrointestinal Malignancies
Termeer Center for Targeted Therapies
Super bummed to not be in person
@ASCO
HQ today with our Education Scholars Class about a week in and still this. Prior infection March 2020 and this will hopefully be very good for next time with
@drjennifergao
@DrMMurphy
@DocLHenry
@doctormb1
Absolutely delighted to join the Board of the
@btfoundation
have been impressed with the work and mission of
@binayshah
not only to provide access to cancer care in LMIC but with a very intentional emphasis on high quality care!
Mother’s Day on the Covid service staffed by oncologists. you can take us out of oncology but can’t take oncology out of us . Chief fellow chris nabel schooling
@ZPiotrowskaMD
@AnnaFaragoMD
and myself on his love, metabolism in cancer
@MGHCancerCenter
Amazing panel discussions in Global Townhall on Precision Oncology
@RFhospital
@karkinoshealth
@PrashantK_PhD
Discussing provocative Genomics based tumor classification in the Precision era!
From science
@AACR
to advocacy! Thank you
@ASCO
for naming me an Advocacy Champion @ the
#ASCOAdvocacySummit
. proud to advocate on issues like access to clinical trials, increase
@NIH
funding & emergency relief funding for research impacted by
#COVID19
. Looking forward to today!
But really
#TumorBoardTuesday
forced me to finally figure out a
#tweetorial
🤣 turns out 10k citations won’t make the character count. Excited to see how others would have managed this case with a few twists and turns but 🤫 spoiler alert. 🤞🏽good outcome
called into gathering of remarkable humans remembering
#PaulFarmer
My day job is clinical/translational, but reminder of why I chose onc-Cancer care isn’t just for born privileged. Despite often feeling low in this work,his hope reminder for us all do more & be better.
#globalonc
Somedays (often) joke about retirement but other days just this these simple words and I’m a tearful mess grateful for this as my life’s work as I skim through a beautiful coffee table book “Thank you” from a patient at the end of the day ❤️
Wrapping up run on c19 team til next in a week’ish.Tiring.Sad.Lonely for pts. Inequitable. However, camaraderie amazing. urology/ortho nurses w/oncologists figured it out together w/ kindness & humanity. So proud to be
@MGHMedicine
@MGHCancerCenter
@AnnaFaragoMD
@ZPiotrowskaMD
He saw and fought structural racism well ahead of when discussions of structural racism became commonplace, fought for the poorest of the poor and inspired generations of people, including myself, to not accept the status quo. Tremendous loss for the global health community
@NewTimesRwanda
@PIH
Very heartbreaking news on Paul Farmer. A very sad day in the
@PIH
and
@harvardmed
family. Dr. Farmer was truly an inspiration; living a life that brought hope to many. And influencing countless to truly care for and empower the poor and underserved. His legacy will live on...