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Marta Shahbazi Profile
Marta Shahbazi

@Marta_Shahbazi

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Group leader @MRC_LMB . Self-organisation and developmental plasticity during mammalian development

Cambridge, England
Joined December 2016
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@Marta_Shahbazi
Marta Shahbazi
2 months
📢📢New paper alert! The work of Aly, the first PhD student in my lab is out! We have explored the mechanisms of germline entry in the mouse and identified integrin signaling as a new roadblock of primordial germ cell specification. Keep reading:
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@Marta_Shahbazi
Marta Shahbazi
4 years
España me formó. 6 años en un instituto público, 5 años de Biología y un máster en la UAM y 5 años de doctorado en el CNIO. Gracias a las becas jamás pagué nada. Ahora que llegó el momento de devolver a la sociedad la inversión lo hago en el extranjero. #SinCienciaNoHayFuturo
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@Marta_Shahbazi
Marta Shahbazi
3 years
Best way to start 2022: my lab has been awarded an ERC starting grant @ERC_Research !! 🥳🥳🥳🥳 We will be studying how tissue morphology affects pluripotent stem cell fate decisions during mouse and human development. Stay tuned for updates!
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@Marta_Shahbazi
Marta Shahbazi
4 years
8 transcription factors are sufficient to transform pluripotent cells into oocyte-like cells!
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@Marta_Shahbazi
Marta Shahbazi
5 years
The most exciting news I will probably ever share in Twitter: I am honoured and thrilled to announce that I am officially starting my own group at the LMB in Cambridge! I will be looking for a postdoc soon so stay tuned!
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@Marta_Shahbazi
Marta Shahbazi
3 years
Defining myself as a mother scientist
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@Marta_Shahbazi
Marta Shahbazi
5 months
So happy to see our happy spheroids on the cover of @Dev_Cell !!
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@Marta_Shahbazi
Marta Shahbazi
4 years
First paper of the Shahbazi lab: a review on human embryo development. I wrote it during maternity leave and lockdown, and so it is very special for me. I hope you will enjoy reading it as much as I enjoyed writing it!
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@Marta_Shahbazi
Marta Shahbazi
7 months
Extremely happy to share the first manuscript of the lab! 🥳🥳🥳In this paper, we have looked at the coupling between delamination and differentiation at gastrulation. If you are interested in pluripotency, gastrulation, and mouse embryos keep reading!
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@Marta_Shahbazi
Marta Shahbazi
5 years
Our first trip as a family: an Italian dad, a Spanish mother and a British daughter. Tomorrow vote to keep us all together, vote against borders and for unity. #VoteTactically
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@Marta_Shahbazi
Marta Shahbazi
5 years
It was a matter of time, and finally someone did it! Intravital imaging of mouse embryos:
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@Marta_Shahbazi
Marta Shahbazi
4 years
New paper!! What happens when the number of cells in an embryo is increased? The dynamics and mechanisms of embryonic morphogenesis change! Amniotic cavity formation is delayed and requires cell death
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@Marta_Shahbazi
Marta Shahbazi
2 years
More than 15 years ago visiting Iran with my family I was stopped by the morality policy. They just told me: go to the van!! I was paralysed. There was just one empty seat in the van, waiting for me, the rest already occupied by other young teenagers. My father quickly said...👇🏼
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@Marta_Shahbazi
Marta Shahbazi
2 years
After two years and 8 months of paperwork to import human morulas from Spain for research, we have finally received them!! One million thanks to @URH_GdR and all the patients that donated their embryos. We will try our best to learn as much as we can from them
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@Marta_Shahbazi
Marta Shahbazi
4 years
I am very honoured to receive this award. Thank you so much to the 3Rs and GSK for the recognition of our work.
@NC3Rs
The National Centre for the 3Rs
4 years
Congratulations to both of our 2019 #3RsPrize winners, who will each receive a £15k prize grant and a £2k personal award for their outstanding contributions to 3Rs research.
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@Marta_Shahbazi
Marta Shahbazi
4 years
The Shahbazi lab website is finally live!
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@Marta_Shahbazi
Marta Shahbazi
1 year
📢Applications for the LMB PhD programme are now open. The LMB is without any doubt a fantastic place to do a PhD! This year I am recruiting. If you are interested please get in touch
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@Marta_Shahbazi
Marta Shahbazi
2 years
Introducing science at an early age. First visit to the @MRC_LMB of my 3 days old baby
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@Marta_Shahbazi
Marta Shahbazi
2 years
The bravery of Iranian women is absolutely remarkable. They risk their lives to fight for their freedom and we should do everything we possibly can to support them #Masha_amini #IranRevoIution2022
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@Marta_Shahbazi
Marta Shahbazi
1 year
6 papers reporting embryo models in less than a month it’s a lot to digest! And this is why I decided to give a journal club comparing the 6. Really useful discussion with the lab and our special guest @BailWeatherbee
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@Marta_Shahbazi
Marta Shahbazi
4 years
New paper alert! We have analysed the mechanism of cell polarisation in the human embryo and how this influences the first cell fate decision. Continue reading if you want to know more! 👇👇👇👇
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@Marta_Shahbazi
Marta Shahbazi
1 year
Recruitment alert!! The Cell Biology division of the LMB is looking for a junior group leader. Core funding, amazing facilities, freedom to pursue your ideas, collaborative environment, and great colleagues. Any questions please get in touch.
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@Marta_Shahbazi
Marta Shahbazi
5 months
Someone was really paying attention to her mummy talking about human embryo development #PintOfScience #momademia
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@Marta_Shahbazi
Marta Shahbazi
4 years
The first plate of cells is growing in the Shahbazi lab. I had never been so excited about feeders!! 😄😄 #newPI_in_corona_times
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@Marta_Shahbazi
Marta Shahbazi
5 years
Best first day! :)
@MRC_LMB
MRC Laboratory of Molecular Biology
5 years
How do cells know what to become? @Marta_Shahbazi , who joins the LMB today, aims to understand the molecular mechanisms that govern cell identity, a fundamental question that involves multiple levels of biological organisation. Welcome to the LMB! #stemcells
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@Marta_Shahbazi
Marta Shahbazi
5 years
Today my baby Alma went to her first lab meeting. She is only 4 weeks old but it’s never too early to start learning about human embryo development! #womeninstem
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@Marta_Shahbazi
Marta Shahbazi
4 years
Finally published!! I really enjoyed this collaboration with Manuel Serrano and Cian Lynch from the @IRBBarcelona . Inhibition of CDK8/19 stabilises naive pluripotency in mouse and human ESCs
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@Marta_Shahbazi
Marta Shahbazi
4 years
Un placer hablar con Iker de embriones, células madre y el futuro de la investigación sobre el desarrollo humano
@Diego_FDM
Diego Marañón
4 years
Conectamos EN DIRECTO con @Marta_Shahbazi , bióloga de la Universidad de Cambridge, para analizar una de las noticias de la semana en el ámbito científico. #MilenioLive
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@Marta_Shahbazi
Marta Shahbazi
3 years
The Cell Biology Division of the LMB is recruiting group leaders! This is a unique opportunity! I cannot recommend it enough. Don't hesitate to apply and please reach out if you have any questions
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@Marta_Shahbazi
Marta Shahbazi
22 days
The field of embryo models is advancing very quickly. @vincentpasque and I have tried our best to present the current status of the field and deconstruct all the complexity in this review. If you want to know more keep reading!
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@Marta_Shahbazi
Marta Shahbazi
5 years
If you are looking for a postdoc and are interested in pluripotency, human embryos, epithelial tissues and reprogramming get in touch!
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@Marta_Shahbazi
Marta Shahbazi
2 years
Check out the special issue on human embryo development that @nmoris and myself put together. Really great reviews! Thanks a lot to all the authors that contributed.
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@Marta_Shahbazi
Marta Shahbazi
5 years
Really enjoyed writing this review with Eric Siggia and @ZernickaGoetz . Hope you will enjoy it as well!
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@Marta_Shahbazi
Marta Shahbazi
2 years
“She is a foreigner! She doesn’t know how to wear the hijab properly” After telling me off, they let me go. I was soo afraid, the following day I made sure I was fully covered. When a society is built around fear is easy to become paralysed, blocked, and unable to think... 👇🏼
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@Marta_Shahbazi
Marta Shahbazi
4 years
A new working routine
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@Marta_Shahbazi
Marta Shahbazi
2 years
Let me introduce you to my two super postdocs Viviane Rosa @Viviane13825742 and Nanami Sato @773ssss . I am the visible face, currently presenting their work at #ECCDB2022 , but they are doing the hard work! #PostdocAppreciationWeek
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@Marta_Shahbazi
Marta Shahbazi
2 years
My personal view on the fundamental paper on size regulation by Janet Rossant and collaborators. A classic that everyone should read!
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@Marta_Shahbazi
Marta Shahbazi
4 years
Going back home, spending time with my family, going out with my high school friends, running San Silvestre... None of that is happening this year. But at least thanks to science there is light at the end of the tunnel! Merry Christmas, specially to those that are far from home!
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@Marta_Shahbazi
Marta Shahbazi
4 years
This is incredible!! Single cell atlas of an in vivo developing human embryo at the gastrula stage. @VallierLab @anto_scial
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@Marta_Shahbazi
Marta Shahbazi
8 months
Congratulations Dr. Makhlouf!! It has been a pleasure to have you as the first PhD student of the Shahbazi lab. Thanks to the examiners for the discussion and to everyone in the lab for creating such an amazing PhD hat! 😊😊 #proudPI
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@Marta_Shahbazi
Marta Shahbazi
7 months
Thank you so much @ISSCR for approving my application for a child dependent care grant to attend the annual meeting! Initiatives such as this have such a huge positive impact. In my case, it means me, my baby and my parents are going to #ISSCR2024 ! 😃
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@Marta_Shahbazi
Marta Shahbazi
1 year
Don’t miss the #LMBopenday today! So much to learn and so much fun!
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@Marta_Shahbazi
Marta Shahbazi
4 years
I am really happy to see this work from @ZernickaGoetz lab finally published! Fantastic work from the fantastic @zhumeng123 ! Congratulations to everyone! Keep reading if you want to know more about early embryos, polarity and time
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@Marta_Shahbazi
Marta Shahbazi
3 years
New paper alert! How do early human embryos polarise? This work involved so many IVF clinics and collaborators across the globe. I am so glad to see it finally published!
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@Marta_Shahbazi
Marta Shahbazi
5 years
I am looking for a postdoc to join me at the LMB in February. Scientists at the LMB tackle “fundamental, often difficult and long-term research problems”. Get in touch if you are up for the challenge!
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@Marta_Shahbazi
Marta Shahbazi
2 months
Gastrulation enthusiasts: don't miss the new article from Isabelle Migeotte's group! Non-apical mitoses contribute to delamination during mouse gastrulation. I am very happy to be part of this work and to see that our 3D EpiSC model was useful!
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@Marta_Shahbazi
Marta Shahbazi
2 years
La burocracia va a matar a la ciencia española. Una clínica de FIV con la que colaboro solicitó un permiso de exportación de embriones a la Comisión Nacional de Reproducción Asistida. Un año después nos informan de que la solicitud la tengo que hacer yo y tenemos que empezar de 0
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@Marta_Shahbazi
Marta Shahbazi
4 years
So many cool articles in Nature today! Mouse embryos cultured in vitro from E5.5 to E11! 🤩Amazing achievement from @jacob_hanna and colleagues. And new stem cell models of the human blastocyst.
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@Marta_Shahbazi
Marta Shahbazi
2 years
I am so glad to know our work is the most read paper in @stemcellreports !!
@CellPressNews
Cell Press
2 years
Embryo size regulates the timing and mechanism of pluripotent tissue morphogenesis @Marta_Shahbazi @Viviane13825742 @frantonica @KyprianouChr @ZernickaGoetz Most read paper from @stemcellreports @ISSCR @martinperaJAX
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@Marta_Shahbazi
Marta Shahbazi
6 years
Finally out! Don’t miss it if you are interested in innovations to study the early mouse and human embryo. I hope people will enjoy reading it as much as I enjoyed writing it 😊 @NatureCellBio @ZernickaGoetz
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@Marta_Shahbazi
Marta Shahbazi
2 years
This is such a nice cover. Congratulations @MZG_Lab ! @ZernickaGoetz I have learned so many valuable lessons from you, and the importance of having an artistic mindset when doing science was definitely one of them.
@NatureCellBio
Nature Cell Biology
2 years
👉Check out our September issue! #SyntheticEmbryos on the cover! 🪂Dive into #CellularPlasticity , TDP-43 pathology & #PhaseSeparation , #mTORC1 control, #LipidDroplet targeting, a #CRISPR method, #exctracellularvesicles , a Review on #transposons &more!
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@Marta_Shahbazi
Marta Shahbazi
4 years
@GemmaSue1329 Totalmente de acuerdo. Fue una decisión personal no volver y quedarme fuera. Las condiciones que tengo aquí no las tendría en España.
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@Marta_Shahbazi
Marta Shahbazi
2 years
Are you ready to become a group leader? Are you looking for a supportive environment and really nice colleagues? Do you want freedom and resources to follow your best ideas? Then apply to the group leader call of the LMB Cell Biology division!
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@Marta_Shahbazi
Marta Shahbazi
3 years
A pleasure to write about the recent human blastoids from the @NRivron lab. The field is advancing so quickly!
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@Marta_Shahbazi
Marta Shahbazi
3 years
On my way to the 12th DB course @institut_curie . I cannot be more excited! My first in person meeting since the pandemic began! Also my first night away from my daughter since she was born. I will definitely miss her! #motherscientist
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@Marta_Shahbazi
Marta Shahbazi
5 months
A Cambridge must: formal dinner of the Shahbazi lab. The next item on the list is punting!
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@Marta_Shahbazi
Marta Shahbazi
8 months
The EMBO leadership course should be mandatory to all new group leaders. Fantastic experience, food for thought, and a list of changes to implement in the lab!
@MetteHL
Mette Hvied Lauesen
8 months
Just spent 4 very fulfilling days in Cambridge with MRC-LMB & S. Leadership isn't all about whipping people up for results and these people got that. @MelanieGlickman @LifeSciLearn @LeadSculpt
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@Marta_Shahbazi
Marta Shahbazi
25 days
I am very excited to learn that our findings in PGCs extend to other species and tissues. Extracellular matrix signaling also inhibits the Wnt signaling pathway in the context of brain organoids!
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@Marta_Shahbazi
Marta Shahbazi
4 years
I am really happy to see the first edition of the Stem Cell Report podcast! This is a fantastic initiative. I really enjoyed listening to Janet Rossant and Patrick Tam while I was dissecting E5.5 embryos. Very inspiring!
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@Marta_Shahbazi
Marta Shahbazi
3 years
Merry Christmas everyone! This year we managed to leave the U.K. to see our family abroad and this is the best present one could ever have.
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@Marta_Shahbazi
Marta Shahbazi
10 months
Run first, celebrate later. Happy 2024! #SanSilvestre
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@Marta_Shahbazi
Marta Shahbazi
8 months
Thank you so much for the nomination! I am really honoured. I hope to inspire many talented women to pursue a scientific career. We can! 💪
@KellyTHD_Nguyen
Kelly Nguyen
8 months
Congratulations our colleague @Marta_Shahbazi and all other awards winners this year!
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@Marta_Shahbazi
Marta Shahbazi
3 years
Talking to high school students about my experience as a female scientist. I can't think of a better way to celebrate International Women's day!
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@Marta_Shahbazi
Marta Shahbazi
1 year
While I hug my kids in bed I can’t stop thinking about all the parents that lost their kids, all the kids that lost their parents, and all the families that hug each other at night praying they will see the light of another day. My heart is with you
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@Marta_Shahbazi
Marta Shahbazi
5 years
A great resource for those studying the human embryo: transcriptome and methylome of human embryos cultured in vitro beyond implantation. So glad to see different independent groups using our culture method successfully!
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@Marta_Shahbazi
Marta Shahbazi
3 years
The COVID pandemic has impacted our lives in many different ways. Thanks to @CellStemCell for giving visibility to the struggles, ambitions and hopes of early career scientists. It was a pleasure to share my experience as a mother scientist
@CellStemCell
Cell Stem Cell
3 years
Over the past year, we've featured 71 early-career researchers who discussed their research and the COVID-19 pandemic's impact on their labs & lives. We mark the closing of this article series with interviews and essays from some of the participants.
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@Marta_Shahbazi
Marta Shahbazi
5 years
Baby Alma got her first round of vaccines today. Of course she cried, but by vaccinating her we are contributing to create a world free of preventable diseases. Vaccines save lives! #VaccinesSaveLives #VaccinesWork
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@Marta_Shahbazi
Marta Shahbazi
1 year
I really enjoyed reading this paper! A beautiful example of how powerful live imaging can be.
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@Marta_Shahbazi
Marta Shahbazi
3 years
To those living in Cambridge: last Friday I lost this silver pendant. It has an extremely important sentimental value. The chances are very small, but if anybody has seen it please let me know. Thanks!
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@Marta_Shahbazi
Marta Shahbazi
3 years
To end the PostDoc appreciation week I want to introduce my two fantastic postdocs Viviane and Nanami ( @Viviane13825742 and @773ssss ) @MRC_LMB . Thanks for all your dedication, hard work and enthusiasm! #NPAW2021 #lovepostdocs
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@Marta_Shahbazi
Marta Shahbazi
3 years
Are you interested in imaging, morphogenesis, and mechanical forces? Do you want to join an interdisciplinary lab to work on an exciting project? Then look no further and apply for the postdoc position available in Kate McDole's lab!
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@Marta_Shahbazi
Marta Shahbazi
2 years
The ERC grant, @Viviane13825742 birthday, Melinda’s farewell party, and a very delayed Christmas celebration. It was definitely time to get together! #bestlabever
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@Marta_Shahbazi
Marta Shahbazi
2 years
Merry Christmas to everyone! I hope you are having a lovely holiday break. For me Christmas means family and friends, sleeping without setting up an alarm, reading a book, long walks in the city, and visiting the nativity in church. Food for the soul and energy for the new year!
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@Marta_Shahbazi
Marta Shahbazi
4 years
Today I say thanks to the exceptional mentors that I had during my scientific career. They are examples of truly amazing women in STEM @ZernickaGoetz @perezmorenolab #InternationalWomensDay
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@Marta_Shahbazi
Marta Shahbazi
24 days
If you are interested in using our 3D EpiSC model, we have just published a detailed protocol. Any questions please get in touch!
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@Marta_Shahbazi
Marta Shahbazi
6 years
Brilliant!
@JKCorden
James Corden
6 years
This is the best description of brexit From @JamesAcaster
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@Marta_Shahbazi
Marta Shahbazi
1 year
I just googled "blastoid" and found out "Blastoids are an extinct type of stemmed echinoderm, often referred to as sea buds". Lots of beautiful fossil images instead of embryo models!
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@Marta_Shahbazi
Marta Shahbazi
4 years
For #postdocappreciationweek let me introduce the first postdoc of the Shahbazi lab! Nanami Sato studied cell competition in epithelial tissues during her PhD. For her postdoc she will be looking at how epithelial tissue organisation affects pluripotent cell identity @773ssss
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@Marta_Shahbazi
Marta Shahbazi
4 years
@j_cantoral @ERC_Research It would be good to know how many women and men applied. Is the female/male ratio of applicants and awardees conserved? This would help us understand whether reviewers could have an unconscious bias
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@Marta_Shahbazi
Marta Shahbazi
3 years
I really enjoyed reading this review from @Morgani_S and Kat Hadjantonakis. Everything I ever wanted to know about signalling during gastrulation!
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@Marta_Shahbazi
Marta Shahbazi
2 years
Today's reminder: just because a field is "hot" doesn't mean that we should drop the bar of scientific rigor
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@Marta_Shahbazi
Marta Shahbazi
2 years
See you soon Barcelona! The #EIWConf was really fantastic. I had engaging scientific discussions, bring with me a list of ideas/questions to think about, saw old and new friends, and even sat on @viktri08 chair to chat with @XavierTrepat !
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@Marta_Shahbazi
Marta Shahbazi
23 days
This is a really important article. There are plenty of human embryos available for research, and even when patients would like to donate them for research, in most cases this does not happen. Now more than ever, we need more human embryo research.
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@Marta_Shahbazi
Marta Shahbazi
7 years
When I told my high school Physics teacher that I wanted to study Biology to be a scientist he replied "you will end up been a cashier". 17 years later I want to tell every girl: you can follow your dreams
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@Marta_Shahbazi
Marta Shahbazi
5 years
Non genetic information in the cytoplasm is sufficient for self-organisation. How cool is that?
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@Marta_Shahbazi
Marta Shahbazi
2 years
How am I supposed to look for "Brachyury" in papers if T is used instead? Control + F is useless! 😩
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@Marta_Shahbazi
Marta Shahbazi
9 months
So important to be frequently reminded of every single point in this list!
@ardemp
Ardem Patapoutian
9 months
I wrote down my rules on how to Science. I hope you find it useful!
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@Marta_Shahbazi
Marta Shahbazi
5 years
Snake venom gland organoids from @TheCleversLab . How cool is that??
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@Marta_Shahbazi
Marta Shahbazi
4 years
If you want to know more about 3D cultures, don't miss this panel discussion:
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