I am thrilled to share with you a great piece of work that will hopefully bring some more understanding into the impact of MRI Markers on the diagnostic performance of the international Parkinson and Movement Disorder Society Multiple System Atrophy Criteria.
I have been at
@BritishNeuro
#BNA2023
conference yesterday. I have spoken about the importance of neurosurgical obtained brain tissue specimens for neuroscience research. It was a privilege.
#neuroscience
#medtwitter
My late uncle was a role model of strength, power, character and a grand human being all together. He is not with us anymore but retrospectively reflecting I remember he once told me - donโt let any moment go to waste. Therefore I use my weekends to do sports, read and make the
Friday
#cycle
๐ดโโ๏ธ This can be great for mental clarity and brain health. The rhythmic movement and aerobic exercise involved in cycling do promote the release of
#endorphins
, which are chemicals in the
#brain
that help reduce
#stress
and boost
#mood
. Regular cycling can improve
Lastly for today, the British Neuropathology Society hold its 125th meeting in the next couple of days. Feels good to have the chance to stay up to date with outstanding research and medical work.
#bns24
@BNS_updates
@RCSnews
This is a place of excellence where I had the privilege to meet extraordinary people with exquisite minds and character. Always striving to become the best at what they do and relentlessly finding cures or writing articles helping further science for people's benefit!
Ever wondered what a brain bank does? ๐ง ๐ก Brain banks collect, store, and distribute brain tissue for research into neurological disorders. We are vital hubs for advancing our understanding and treatment of brain-related conditions.
#Neuroscience
#lifeatkings
#kclbrainbank
I am thrilled and humbled to be part of this educational series with KCL Brain Bank! ๐ง ๐ก Crafting posts that shed light on neuroscience, neurodegeneration, neurology, neuropathology, and the intricacies of the human brain is not just a passion but a privilege. Together, we're
My friend Tin Tin is donating her hair! Please consider supporting this wonderful cause- even just donating ยฃ1 or spreading the word means so much. Such an amazing and selfless work she is doing!
@macmillancancer
@LPTrustUK
Hybrid
#training
๐๐ฝ๐ฒ๐คธ๐ผ blends different exercise modalities like resistance training and cardiovascular ๐ซ workouts, offering a holistic approach to fitness. Its medical benefits include improved cardiovascular health, enhanced muscular strength and endurance, weight management
A common myth about thrombotic thrombocytopenic purpura (TTP) is that it primarily affects older adults. In reality, TTP can occur at any age, including in children and young adults. It's important to recognize the diverse demographic range affected by this disorder. ๐จ๐ฝโโ๏ธ๐งซ๐ฌ
Tofersen, or BIIB067, developed by Biogen, is a key treatment for ALS, just as
@AmmarAlChalabi
details below and in the article. Sadly, the priority here is politics and economics instead of offering somebody life-changing therapeutics.
#mnd
#als
Tofersen is an effective therapy for the 2% of people with
#ALS
#MND
who carry a genetic variation in their SOD1 gene. Whether it is available in the UK depends on a cost threshold and assessment by
@NICEComms
. The system is outdated:
@UKMNDRI
@mndassoc
The
#alsmndsymp
in Basel is in progress. Working very close to this pathology feels good to know awareness is being raised as well as efforts are maximised in improving research. ๐ฌ๐ง ๐ฉ๐ฝโ๐ฌ
The
#MND
#ALS
clinical trial session at
#alsmndsymp
is packed!
In this session we will hear some latest updates from trials running all over the world. ๐
This May, I support the โForget Me Notโ appeal to raise awareness for those with Dementia. I stand with those affected by it and those who tirelessly fight against it.
@alzheimerssoc
๐ชป
A glimpse of the past week ๐ง ! Weโre all off to vacation/annual leave and this couldnโt come at a better time to go enjoy the Happy Jolly Season โ๏ธ๐โ๏ธ๐จ๏ธ๐ ๐ป
PRNRP tumours typically exhibit a papillary architecture, but they have a different pattern of cell polarity compared to other papillary renal tumors. The identification of this subtype is crucial for accurate diagnosis and appropriate management!
#gupath
Oligodendroglioma involves the assessment of specific genetic mutations and codeletions, including IDH1 or IDH2 mutation, TERT, and 1p/19q codeletion. Genetic alterations play a crucial role in the diagnosis, prognosis, and treatment.
#pathology
#PathTwitter
Even the non-
#neuropath
people can take a crack at diagnosing this brain mass in a thirtysomething year-old woman. One slide is all you need. What's the diagnosis and probable genotype?
#pathology
#PathTwitter
Solitary fibrous-type tumours are characterized by hypercellular areas composed of spindle cells and hypocellular fibrous areas. In contrast, the cellular type shows a monotonous appearance with moderate to high cellularity and little intervening fibrous tissue.
#neuropath
#PathX
Neurocytoma is a rare type of brain tumor that typically arises in the ventricles, fluid-filled spaces within the brain. These tumors are usually slow-growing and can be either benign or, in some cases, have malignant potential.
#neurosurgery
#neuropath
๐ง ๐ฌ๐ง๐ปโโ๏ธ
The axial FLAIR shows a large central neurocytoma with typically cystic features. The SWI (shown here) shows dark susceptibility artifacts that likely represents calcifications commonly seen in these tumors.
Learn more here:
#MedTwitter
#NSGY
#surgery
Huge thanks to
@NeuroSxAminul
for organising yesterdayโs traumatic brain injury day!
#neuroscience
and
@KingsNeuro
department at
@KingsCollegeNHS
should make this a habit as raising awareness is key for an efficient early diagnostic, management and treatment in any pathology.
According to studies, the incidence of
#haematomas
resulting from
#traumatic
#brain
#injuries
is high and life-threatening.
#Epidural
Hematomas (EDH) occur in about 2-4% of TBI cases.
#Subdural
Hematomas (SDH) are more common than epidural hematomas and can occur in up to 30% of
Sundays surgery,
Epidural hematoma drainage
It is a collection of blood that forms between the inner surface of the skull and the dura, typically biconvex in shape, and can cause a mass effect with herniation.
As the most junior of them all, all I could say is - it wasnโt too bad presenting๐๐ผ it was a good experience. Thanks
@BNS_updates
#bns2024
also Prof Safa Al-Sarraj, Dr Zita Reisz and Dr Claire Troakes for offering me the platform to express my passion. ๐๐ป
The Beating brain ๐ง - Its Normally pulsatile . It beats with each heart beat .
See the beauty of brian - This part controls everything . Appretaite the beautiful arteries veins on surface. We all have this inside- the perfect machine created by God . ๐
#Cycle
to
#work
definitely offers the following for me:
๐ง Mind-Body Connection
๐ Stress Management
๐ฃ๏ธ Social Community
๐ Belief in Yourself
๐ Mood Enhancement
๐ฏ Goal-Setting and Achievement
๐ Continuous Learning
๐ Health
Oh and youโd be surprised how much youโre
Here's a dural opening to reveal a subdural haematoma performed by
@gcmarhx
followed by gently removal with suction and irrigation. Most probably the skull is put back in place and secured using metal plates or screws or left open (brain flap) until possible swelling is reduced.
The reason for encephalococele forming could have many faces like abnormal development of the neural tube, genetic factors, environmental, mechanical. Preponderantly in the back due to structural weakness, influence of gravity and inherent vulnerability.
This was my evening ride! I purposefully took a bit longer to squeeze in more cycling time. ๐ดโโ๏ธ๐ดโโ๏ธ๐ดโโ๏ธ๐ดโโ๏ธ๐ดโโ๏ธ๐ดโโ๏ธ
#avbrainhealth
It is never too late to improve your mindset by prioritising your brain health. I am a strong believer in mental wellbeing especially in the world we live in
Did you know the frontal lobe is the biggest lobe in the human brain? It is delimited posteriorly by the central sulcus and inferiorly by the lateral sulcus. It extends anteriorly to the frontal pole, which is the most anterior part of the brain. ๐ง
#avneuro
#clinicalneuroscience
We are proud to be research tissue providers for several researchers and other companies and working with some great names. Send us an email at - brain.bank
@kcl
.ac.uk for any enquiries related to tissue requests!
#kclbrainbank
#neuroscienceresearch
#braintissue
Great evening Understanding Pediatric CNS Tumors through Multi-disciplinary & Multi-omics Analysis by Jason Chiang, MD, PhD research neuropathologist at
@StJude
๐ฌ๐ง
@UCLIoN
@UCLBrainScience
@uclmedsci
For the past year and so, I have had the pleasure of working with Dr Claire Troakes, and it has been nothing but a pleasure and an extreme learning opportunity. I am so very thankful and suggest everyone takes a look at what these people do at the
@LNDBrainBank
The Brain Bank at King's College London (KCL) delves into the depths of neurological disorders, with a focus on Alzheimer's, Parkinson's, and Huntington's diseases.
A new donation came in last week - a vascular dementia case. VD is a type of dementia that occurs when there is significant damage to the brain's blood vessels, resulting in reduced blood flow to parts of the brain.
#kclbrainbank
#neuroscienceresearch
#braintissueprovision
Carotid endarterectomy (
#CEA
) is a
#surgical
procedure to remove plaque buildup from the
#carotid
#arteries
, major blood vessels in the neck that supply blood to the brain, leading to
#stroke
, reduced blood flow to the brain, and vascular dementia. This buildup of plaque is known
Subdural hematoma (SDH) is a serious condition where blood collects between the layers of tissue surrounding the brain. It often occurs as a result of traumatic brain injury (TBI), particularly in cases of head trauma.
Caseย
#Repost
: A subdural hematoma is a collection of blood under the dura matter, the protective layer of the brain. It typically occurs due to head trauma.
#Neurosurgery
#MedTwitter
๐ Celebrating LGBTQ+ History Month at NHS ๐ฅ I salute our incredible NHS medicine workers who contribute to healthcare with dedication. Our diversity makes our healthcare system stronger, more inclusive. Thank you! ๐ณ๏ธโ๐
#NHS
#LGBTQHistoryMonth
#HealthcareEquality
Tomorrow is the start of LGBT+ History Month 2024 and this year's theme is medicine
#UnderTheScope
It aims to showcase the amazing work of LGBT+ staff across the NHS, in providing healthcare, especially during the pandemic.๐คฉ๐
Find out much more here
@CraigHorbinski
I am sure somebody though of it by now but I guess tissue act legislation poses a big challenge to use this tissue. It will be hard to get consent for this.
Talking about positives! I often run ๐โโ๏ธ, cycle๐ฒ, walk ๐ถโโ๏ธ, go gym ๐๐ฝ and I realise how the pandemic ๐ฆ had some benefits as well. I see lot more people run in groups as social clubs, or by themselves, do other sports. All types of people, cultures, religions, together united by
PD is a sensitive topic personally, hence I was curious to participate in Professor Anthony Schapiraโs lecture. Bottom line your gut dictates your life. ๐๐ป๐ง ๐ฌ Thank you
@BNS_updates
for a nice conference opening.
This Sunday, I achieved a personal milestone by completing my longest distance yetโ35.4k in the
#AroundTheBay
road race in Hamilton. Grateful for my amazing support team whose encouragement doubled my joy. Big hugs to them! ๐โโ๏ธ ๐
Hereโs a case of kidney ๐ซstones ๐caused probably by dehydration. These calculi are usually Ca or Mg. The diagnosis could be bilateral urolithiasis ๐จ๐ฝโโ๏ธ as we see two calculi on each side on the scan.
Whoop whoop - my invite to the 10th IoPPN research festival has arrived. This will be the hottest ticket in town so sign up soon peeps.
@KingsIoPPN
#IoPPNfestival
The presence or absence of a basement membrane in muscle cells can be attributed to the specific roles and functions of different muscle cell types within the body. Muscle cells, also known as myocytes, can be broadly categorized into three types: skeletal, cardiac, and smooth
๐คWhy do some cells, or groups of cells, have a basement membrane and others don't? Students are often confused when we discuss the muscle fibre basement membrane during muscle regeneration so I'm looking for more insight - thank you!
@THEmeshwork2020
Every step taken to prioritize mental health is a stride towards a brighter, more resilient tomorrow. Let's break down stigma, foster empathy, and build a world where seeking help is a sign of strength, not weakness.
#MentalHealthMatters
๐ง
London Neurodegenerative Diseases Brain Bank Tour for our friends at
@StudyEstra
@SGDPCentreKCL
- We chatted about our role and the importance of
#neuroscience
#research
. We added a short neuroanatomy and neuropathology run-through with a Q&A session at the end.
#MedTwitter
Renal cell carcinoma is the most common type of kidney cancer in adults. Symptoms may include blood in the urine, back pain, or a mass in the kidney area. Treatment options vary depending on the type, size, and stage of the tumor and may include surgery, radiation therapy.๐ฌ
Hemophagocytic Lymphohistiocytosis (HLH) is a rare and potentially life-threatening disorder involving an overactive immune system. Diagnosis is often based on established criteria, such as the HLH-2004 diagnostic guidelines.
#pathology
#PathTwitter
๐ฉ๐ฝโ๐ฌ๐ง ๐ฌ
I have always liked riding bikes, but my dad was so terrified something might happen to me that he paid his friends to come and steal my bikes so I wouldn't ride them anymore and I'd be safe ( a very true story). Riding a bike, whether a traditional bicycle or an electric bike
Morning bike commute, better for your cardiovascular system, improve respiratory system and gives an optimal brain oxygen supply. ๐ง
#avbrainhealth
#albertvamanu
#avhealth
I don't think people understand how hard it is to get yourself out of a dark place in your mind๐ง . For everyone who did that today, keep going! Be proud of yourself and know there are people that love you and want to see you happy ๐.
We had a full lab yesterday introducing new MSc
#Neuroscience
students to brain donations, tissue processing, tapping into pathology, histology, tissue processing, and anatomy. It was a great day! ๐
#NeuroTwitter
Neurons inside a sensorimotor organoid over a period of six weeks.
You can see them form these bundles and organize - there are a ton of cells (non-neuronal) around them!
(hSyn::GFP)
I was always so fascinated by
#histology
I came to realise this beauty doesn't always mean something good. Just as in this case
#metastatic
#melanoma
?
@zita_reisz
, correct me if I am wrong, please. ๐ฉโ๐ฌ๐ง
One high-power image of a well-circumscribed brain mass. What do you think it's most likely to be? (Hint: it's at the grey-white junction.)
#pathology
#neuropath
#PathTwitter
Touch prep from a particularly nasty
#glioblastoma
with primitive features. Check out those chromosomes! One could do a karyotype from these mitotic figures. ๐ง ๐ฌ๐ฎ
#neuropath
#PathX
I am still not convinced if the green colour is an artistry missmatch or this is really an intercranial subdural empyema which is a collection of pus in the subdural space between the dura mater and the arachnoid!