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UCLGeneticsInstitute Profile
UCLGeneticsInstitute

@UGI_at_UCL

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UCL Genetics Institute

Camden Town, London
Joined November 2016
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Massive congratulations to @UGI_at_UCL 's Dr @JavierMenRev on his awesome viva success!
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
We are delighted to announce a one-day meeting exploring technologies that go beyond next generation sequencing which will take place on 12 September 2018. Free registration here #ugi #bng18 #longreads
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Congratulations to @UGI_at_UCL Pongsakorn Wangkumhang for successfully defending his #PhD thesis on "Fast and effective statistical methods for detecting genetic #admixture events and its applications in large-scale data cohorts" supervised by Garrett Hellenthal
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper out today in Nature Communications with contributions from UGI's Lucy van Dorp, providing a tutorial on how (not) to over-interpret STRUCTURE and ADMIXTURE barplots #ugi #popgen #admixture
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
A trilogy of @UGI_at_UCL researchers @davecurtis314 @KKuchenbaecker @AidaAndres presenting great talks at the #Fisher computational biology meeting today #interdisciplinary #science #genetics #ugi
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper out today in @NaturePlants from @mscott0106 “A 3,000-year-old Egyptian emmer wheat genome reveals dispersal and domestication history”. How #aDNA from 3000 year old museum Pharaoh’s wheat reveals the history of crop domestication
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper out today in the Annals of Human Genetics from @UGI_at_UCL Professor @davecurtis314 "Clinical relevance of genome‐wide polygenic score may be less than claimed" #ugi #ucl #polygenic #PRS
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Congratulations to @UGI_at_UCL 's @LucyvanDorp on being awarded a prestigious European Research Council Starting Grant to investigate the genetic and ecological drivers of malaria parasites.
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
The UCL Genetics Institute is delighted to welcome a new member sponsored by its director, Francois Balloux. A coffee machine!
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Congrats to @mariasecrier on being awarded a Springboard award from @acmedsci . This award will be used to investigate how gene dosage and copy number instability in the genomes of cancer cells can lead to the development of metastases #ugi #dna #cancer
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
For his public viva to celebrate his PhD graduation, @UGI_at_UCL 's @JackHumphrey_ begins by telling us how he first got interested in looking into how RNA processing abnormalities are involved in human disease.
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Congratulations to @UGI_at_UCL Mislav Acman @misac42 for winning the best 1st year #PhD talk at the Genetics Evolution and Environment Graduate Research Symposium for his talk "Towards a natural classification of bacterial plasmids based on sequence similarity" #AMR #plasmids
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Great talk yesterday from @UGI_at_UCL @mscott0106 at @TheCrick #adna event. Read about his work on the genome of 3000 year old Emmer #wheat in @NaturePlants
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Our September symposium on going Beyond NextGen Sequencing will also feature talks from @AydenizRiki and @OHartwell introducing @pacbio and @nanopore sequencing. Register for free at #ugi #bng18 #longreads
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Congratulations to @UGI_at_UCL #PhD student team for winning the @uclbiosciences PhD pub quiz last night @misac42 @nancybird_ @HoltsmarkSofie . You'll be pleased to hear they aced the #science round! #PhDlife #AcademicChatter #PubQuiz #UCL
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Next weeks @uclbiosciences GEE seminar will be from @PetrovADmitri on the genomics of rapid evolution. Tuesday 11th Feb, 12-1pm, #UCL Roberts Building. All welcome:
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Dr Juan Camilo Chacón-Duque’s Public Viva will be held in the Gavin de Beer LT, Anatomy Building, UCL. Please come along to the talk and join us afterwards for some celebratory drinks! @jcchacond @UGI_at_UCL #phdsuccess #celebration #populationgenetics #latinamerica #ugi
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper in #MBE analyses the #DNA of 223 #EBV global strains. Comparative #genomic and #popgen analyses find that co-evolution of sites under immune selection has shaped #EpsteinBarr #Virus pop structure @fannywegner @LassalleFlo @DanDepledge @BallouxFrancois & Judy Breuer #UGI
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New publication from @liampshaw et al who use a stability landscape framework to model the gut and oral #microbiome after taking a course of #antibiotics @UGI_at_UCL @UCLCoMPLEX #ugi #amr #modelling #interdisciplinaryscience
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@UGI_at_UCL
UCLGeneticsInstitute
9 months
@PGCgenetics @OrchidInc Well what on earth did you think would happen when you made those results publicly available? Completely predictable. You've loved getting all the citations but of course this would be an outcome. Not what all those thousands of patients signed up for when they have you their DNA
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper from @UGI_at_UCL @jcchacond et al. just out in @NatureComms "Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance" #ugi #ucl #popgen #haplotypes #converso
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Congratulations to Dr @JackHumphrey_ for successfully defended his thesis on "RNA dysregulation in models of frontotemporal dementia and amyotrophic lateral sclerosis" supervised by @adrianisaacslab , @VincentPlagnol and Pietro Fratta #ugi #ucl #DrJack #PhD
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
. @UGI_at_UCL @KKuchenbaecker et al on "The transferability of lipid loci across African, Asian and European cohorts" making the important point that genetic associations are not necessarily transferrable to different ancestries/environments @NatureComms
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
When your microbiome is sad! Fantastic public viva (and props) from @UGI_at_UCL latest Dr Liam Shaw #microbiome #phd #ugi #ucl #phdlife
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@UGI_at_UCL
UCLGeneticsInstitute
3 years
Good to see the UK Secretary of State for Health and Social Care, @sajidjavid getting advice on how to tackle COVID from experts including the UCL Genetics Institute's Head of Department, Prof Francois Balloux. @BallouxFrancois @uclnews
@sajidjavid
Sajid Javid
3 years
Productive discussion today on the latest Omicron situation with international experts @mlipsitch , @bencowling88 , @mvankerkhove and @BallouxFrancois .
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New @biorxivpreprint from @UGI_at_UCL @josh_schmidt1 @AidaAndres et al "Evidence that viruses, particularly SIV, drove genetic adaptation in natural populations of eastern chimpanzees" #recentadaptation #ugi #selection #virus #primates #siv
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@UGI_at_UCL
UCLGeneticsInstitute
3 years
. @MSCActions Research Fellow @LehtiSaag has joined @UGI_at_UCL @UCLmacelab @uclbiosciences to study adaptation and demographic processes in Ukraine.
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper from Price et al @lizardburns @ChrisJ_Owen @BallouxFrancois in @GlobalChangeBio @UGI_at_UCL @ZSLScience examing the effects of historic and projected #climatechange on the range and impacts of an emerging wildlife #disease (1/2)
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
If you're curious about long-read sequencing and/or portable sequencers representatives from @PacBio and @nanopore will be able to answer all your questions #ugi #bng18 #longreads
@UGI_at_UCL
UCLGeneticsInstitute
6 years
We are delighted to announce a one-day meeting exploring technologies that go beyond next generation sequencing which will take place on 12 September 2018. Free registration here #ugi #bng18 #longreads
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Today is the day! Gearing up for a fantastic symposium of talks and discussions and ready to learn a lot more about @PacBio and @nanopore sequencing #bng18 #ugi #ucl #longreads #genomes
@UGI_at_UCL
UCLGeneticsInstitute
6 years
We are delighted to announce a one-day meeting exploring technologies that go beyond next generation sequencing which will take place on 12 September 2018. Free registration here #ugi #bng18 #longreads
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
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@UGI_at_UCL
UCLGeneticsInstitute
4 years
Congratulations @mscott0106 !
@MonogramUK
Monogram Network
4 years
The winner of the Post Doc MECEA is Michael Scott at UCL @mscott0106 @JamesHuttonInst @UoDLifeSciences #monogram20
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
@UGI_at_UCL
UCLGeneticsInstitute
6 years
We are delighted to announce a one-day meeting exploring technologies that go beyond next generation sequencing which will take place on 12 September 2018. Free registration here #ugi #bng18 #longreads
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper @PLOSGenetics on the impact of genetic adaptation on #chimpanzee subspecies differentiation. @josh_schmidt1 @AidaAndres et al find strong evidence of recent selection & suggest the role of #SIV in distinct adaptive responses in chimp subspecies
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Congratulations to @UGI_at_UCL Dr Claire Tkacz who successfully defended her PhD on "Computational analysis of innate and adaptive immune responses" supervised by @VincentPlagnol #phdlife #PhDone #ugi #ucl
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
UGI's Dave Curtis urges caution before adopting polygenic risk scores for genetic testing in clinical practice.
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper out today from @UGI_at_UCL @GreatOrmondSt @liampshaw @RonanMDoyle @kathrynharris26 et al Children with cystic fibrosis are infected with multiple subpopulations of Mycobacterium abscessus with different antimicrobial resistance profiles #ugi #amr
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
. @UGI_at_UCL @BallouxFrancois at @pintofscience discussing what can be done to resist the #antibiotic resistance pandemic (with a pint of course!) #pint19 #scicomm #ugi #amr #publicengagement
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New @biorxivpreprint from @misac42 @LucyvanDorp @MICROBIOLOGYUCL @BallouxFrancois "Large-scale network analysis captures biological features of bacterial #plasmids "
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
@fcamus kicking off the UGI Science Meeting+ series talking on "Cracking the black box: how mitonuclear incompatibilities determine fitness" #ugi #mtdna #WomenInSTEM #ucl #postdoclife
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
At the Annals of Human Genetics we are concerned at the way genetic tests are being missold to consumers and we are reviewing our policy regarding publishing papers whose results are likely to be misused.
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New @biorxivpreprint from Shaw & Wang et al on the phylogenetic range of bacterial and viral pathogens of vertebrate hosts. From @liampshaw @cdessimoz @BallouxFrancois et al #ugi #ucl #hostpathogen
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Speaking now at the International Congress of Human Genetics, @UGI_at_UCL 's @KKuchenbaecker addresses the challenge of carrying out genetics research across people of different ancestries. #ICHG2023
@Dr_GHMoen
Gunn-Helen Moen
1 year
@KKuchenbaecker speaking at #ICHG2023 about diversity in genetic studies. @ICHG2023
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
UGI's Prof Dave Curtis prominently featured in today's Guardian. Genetics research 'biased towards studying white Europeans'
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper from Nimmo et al: "Whole genome sequencing reveals Mycobacterium #tuberculosis directly from sputum identifies more genetic diversity than sequencing from culture", with implications for using #wgs to predict #drugresistance phenotypes #amr
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper in Nature Communications on "Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics", featuring work from UGI's Maria Secrier...
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@UGI_at_UCL
UCLGeneticsInstitute
7 years
UGI researchers Yoan Diekmann and @mt_genes , together with a team at @NHM_London , work on genetic analyses of Britain’s oldest complete skeleton in the press today. Dark skin, blue eyes and curly hair! #mesolithic #cheddarman #ugi #nhm #adna @UCLmacelab @Boothicus
@BBCNews
BBC News (UK)
7 years
Cheddar Man: DNA shows early Brit had dark skin
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@UGI_at_UCL
UCLGeneticsInstitute
4 months
UGI's Dave Curtis has been ranked #1 worldwide of Highly Ranked Scholars in Human Genetics by ScholarGPS
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper published today on "Mice with endogenous TDP‐43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis" with contributions from UGI's Jack Humphrey, Kitty Lo...
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New work published today in Nature Communications from Juan Camilo Chacón-Duque Kaustubh Adhikari Macarena Fuentes-Guajardo Javier Mendoza Revilla Garrett Hellenthal and many others. Their work on the genetic history of Latin...
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
We’re looking forward to a great line-up of talks including from @markowetzlab @trevoragraham @gcaravagna @alvinaglai @NickyMcGranahan @fcicca Plus posters, networking opportunities, lunch and drinks @uclcancer @UCLCancerECN #UGIcancer (2/3)
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@UGI_at_UCL
UCLGeneticsInstitute
4 years
. @UGI_at_UCL is planning on relaunching its seminar series featuring internal & external speakers from the wonderful world of #genetics . For those already doing e-talks what has worked well? What hasn't? Potential to open up to a wider audience if there is interest #remoteworking
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
New paper in @SciReports @lizgzil @mt_genes et al "Food Income and the Evolution of Forager Mobility". Increased mobility co-occurs with lower population densities and higher food incomes @UCLCoMPLEX #ugi #AgentBased #mobility #evolution
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@UGI_at_UCL
UCLGeneticsInstitute
2 years
Great to see the work that @UGI_at_UCL alumnus @JackHumphrey_ has been doing on ALS/MND genetics and especially to see the effort he has gone to to make his data and methods accessible!
@JackHumphrey_
Jack Humphrey
2 years
Wonderful to see this work published in @NatureNeuro . Since the preprint, we've worked hard to make this an accessible resource for the #ALS / #MND scientific community in the following ways: 🧵 (1/8)
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
A great setting to celebrate after Dr Juan Camilo Chacón-Duque’s excellent public viva!
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New preprint from UGI's Liam Shaw, Francois Balloux and colleagues on M. abscessus subclones in cystic fibrosis patients, a close collaboration with Great Ormond Street Children's Hospital #amr ...
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@UGI_at_UCL
UCLGeneticsInstitute
2 years
Genomics England announces their plan to genome sequence 100,000 UK babies but @UGI_at_UCL 's Prof David Curtis has expressed concerns that this offers little potential benefit and that the information is vulnerable to being abused.
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
@UGI_at_UCL post-doc Louise Ormond presenting her work on "Inferring the selection history of Europe over the last 10,000 years using a novel statistical approach" at #ISBA8 #ugi #adna #ucl
@amwkim
Alexander M. Kim
6 years
“Inferring the #selection history of Europe over the last 10,000 years using a novel statistical approach” – Louise Ormond #ISBA8 #popgen on an admixture-aware approach to selection inference in dialogue with & compared against Mathieson et al.
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@UGI_at_UCL
UCLGeneticsInstitute
11 months
@generoom @SerenaNikZainal Ah well if you're not a tabixer I'm sure that very shortly VEP will add it as an option on that web page they have where you paste in your variant of interest
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@UGI_at_UCL
UCLGeneticsInstitute
7 years
UCL researchers explain problems with forensic DNA testing:...
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
As the International Congress of Human Genetics meets in Cape Town, South Africa, Fatima and Inouye write in Nature Human Behaviour that: "African genomes hold the key to accurate genetic risk prediction" #ICHG2023
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Elisabeth Bik has done frankly jaw-dropping work exposing widespread scientific fraud. She's speaking at UCL on Thursday afternoon. High likelihood of being awesome.
@_cenk
Cenk Celik
1 year
@UGI_at_UCL @MicrobiomDigest @SelinaWray Location: Lecture Theatre, 33 Queen Square Time: Thursday 6 July 2023, 4.00pm In person: Zoom:
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@UGI_at_UCL
UCLGeneticsInstitute
7 years
New preprint from UGI's Francois Balloux, Lucy van Dorp and Liam Shaw on the global distribution and spread of...
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Congratulations to @UGI_at_UCL @JavierMenRev @kaustubhad @Macarenafg @jcchacond @djbalding and friends for their latest paper in @NatureComms : " A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia" #ugi
@kaustubhad
Kaustubh Adhikari
6 years
Our paper on pigmentation in Latin Americans is now out in Nature Comms. We see 1) a new missense variant in MFSD12, seen only in East Asia and Native Americans, associated with light skin color. Was under selection in East Asia.
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
. @UGI_at_UCL 's @BallouxFrancois contributes to work showing the importance of T cells in producing a rapid response following SARS-COV2 infection.
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper out today in Nature Communications from UCL Genetics Institute's Kaustubh Adhikari, Javier Mendoza Revilla, Macarena Fuentes-Guajardo, Juan Camilo Chacón-Duque, Victor Acuña-Alonzo, David Balding and many...
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Many congratulations to @UGI_at_UCL 's Dr @nancybird_ on acing her PhD viva!
@nancybird_
Nancy Bird
1 year
I passed my PhD viva on Tuesday! 🎉🎊🎉🎊Thanks so much to my examiners @beleza_sandra and Dallas Swallow for an enjoyable discussion!!!
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
Congratulations to Dr Javier Mendoza Revilla for successfully defending his thesis entitled "Detecting signals of selection in the genomes of Native Americans and admixed Latin Americans" supervised by...
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@UGI_at_UCL
UCLGeneticsInstitute
5 years
Registration is open for the next @UGI_at_UCL symposium taking place on the 12th of Feb at #UCL , organised jointly with @UCLCancerECN : "Cancer Genomes: Methods and Challenges for the Next Decade". Link: @uclbiosciences @uclcancer #UGIcancer (1/3)
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
New paper out today in Science Advances describing the global expansion of Mycobacterium tuberculosis lineage 4 and how it has been shaped by colonial migration and local adaptation. Featuring contributions from UGI's...
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@UGI_at_UCL
UCLGeneticsInstitute
6 years
A fantastic talk yesterday on "Zooming in on the genetic history of Latin America" from Juan Camilo Chacón-Duque, followed by celebrations of his successful PhD in UCL main quad #ugi #humanpopgen #phdlife #phd #ucl
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Just out in EJHG, @UGI_at_UCL 's David Curtis reports that the human genome harbours widespread yin yang haplotypes - lengthy regions of multiple markers occurring together as either all reference or all alternate alleles: #ESHG2023
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Good to see many talks at International Congress of Human Genetics addressing the issue that genetic research carried out in white Europeans may be of little benefit to people with other ancestries. #ICHG2023
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
Great way to start the International Congress of Human Genetics in Cape Town - beginning with a celebration of the origins of humanity in Africa! #ICHG2023
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@UGI_at_UCL
UCLGeneticsInstitute
8 years
Dr Saioa Lopez presenting "Genome-wide genetic diversity in Ethiopia and Sudan". 1-2pm 18/11/16 in the Medawar G02 Watson LT. Free lunch!
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
New preprint from @UGI_at_UCL 's David Curtis. Analysis of 470,000 exomes from UKBB identifies novel hypertension genes. Impaired guanylate cyclase activity increases risk. Impaired dopamine beta hydroxylase (synthesises norepinephrine) is protective.
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@UGI_at_UCL
UCLGeneticsInstitute
9 months
@VishTrip_11 Interesting to see the debate about routine genome sequencing of newborn babies being raised in America. @UGI_at_UCL 's Prof David Curtis raised similar concerns about the proposed program in the UK:
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
A review of migraine genetics reports the conclusion published by @UGI_at_UCL 's David Curtis and Katherine Markel that KCNK18 and its product TRESK should no longer be regarded as being involved in migraine aetiology.
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@UGI_at_UCL
UCLGeneticsInstitute
7 years
UGI pleased to announce that we are embarking on functional studies of the #covfefe gene and examining its role in neurodegeneration.
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@UGI_at_UCL
UCLGeneticsInstitute
7 years
Quantitative analysis of cryptic splicing associated with TDP-43 depletion. New UGI preprint from Jack Humphrey...
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@UGI_at_UCL
UCLGeneticsInstitute
11 months
@JenniferRaff This is the home of us, the UCL Genetics Institute. We love it too.
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@UGI_at_UCL
UCLGeneticsInstitute
1 year
. @ucl 's Nikolas Pontikos presents Eye2Gene, a novel AI algorithm for genre prioritisation directly from retinal scans #ESHG2023
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@UGI_at_UCL
UCLGeneticsInstitute
7 years
New review paper on the genetic diversity of the Americas from UGI's Kaustubh Adhikari Juan Camilo Chacón-Duque...
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@UGI_at_UCL
UCLGeneticsInstitute
5 months
@adad8m The mean of HH and HT are the same but HH is skewed with mean higher than median. (Start with just 3 throws to see this.) As number of throws increases to infinity, skewness goes to 0 but with only 100 throws the HT total is higher than HH more often than not.
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