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@OrchidInc

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Meet Orchid, the world's first whole genome embryo screen. Get access:

San Francisco, CA
Joined November 2019
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@OrchidInc
Orchid
8 months
We’re excited to announce the first whole genome screening for embryos is available! Parents can get 100x more data about their embryos’ genomes, empowering them to make an informed decision and give their baby the best chance at a healthy start.
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@OrchidInc
Orchid
3 years
We believe every couple that wants to conceive, should be able to do so confidently. Announcing Orchid, a first-of-its-kind, ultra high resolution genetic testing system for couples.
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@OrchidInc
Orchid
8 months
Thank you to @rohanseth , an early customer and supporter of Orchid. He has dedicated his life to saving his daughter, Lydia, who was born with a spontaneous genetic disease. Through @LydianAcct , he and his wife have translated foreign medical records to find a diagnosis, self
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@OrchidInc
Orchid
4 months
Check out our CEO @noor_siddiqui_ 's profile in Wired! Noor shares her personal story of how she used Orchid for her embryos, her motivation for starting Orchid, and how Orchid helps parents reduce their future child's risk of genetic diseases.
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@OrchidInc
Orchid
3 months
@kirtipatelmd @Wogola0 Hi Dr. Patel! We do 30x whole genome screening on trophectoderm biopsies and can go beyond chromosomal analysis and look at hundreds of monogenic as well as the de novo paternal mutations you’ve alluded to. Thanks so much for drawing attention to this important issue - most
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@OrchidInc
Orchid
8 months
Whole-Genome Screening is a breakthrough in embryo screening (PGT). Most PGT screens <1% of an embryo’s genome, and in rare cases, looks for one known monogenic condition if a couple are carriers. Orchid reads 99% of an embryo’s genome and screens for 1200+ monogenic conditions
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@OrchidInc
Orchid
3 years
Orchid’s focus is to help couples have healthy babies. Today, couples go into the most consequential moment of their life—conceiving their child—blind. Couples have no visibility into how their genetics will impact their future child’s health.
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@OrchidInc
Orchid
8 months
Choosing to have a baby is life changing. Despite advancements in genetics and reproductive technology, there is still a huge amount left to chance. People worry a disease they suffer from, or a family member suffers from, will harm their future child’s wellbeing.
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@OrchidInc
Orchid
3 months
Ever wonder why whole genome embryo screening is relevant for *everyone*, not just those with a known history of genetic conditions? Sometimes, genetic mutations can occur in the embryo that are not present in either parent’s genome - these are called de novo mutations, and
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@OrchidInc
Orchid
8 months
Orchid’s goal is to mitigate the risk of more genetic diseases, and give babies the best possible chance at a healthy life. Starting today, people choosing IVF to build their family can use Orchid’s preimplantation testing to screen their embryos using whole genome sequencing.
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@OrchidInc
Orchid
8 months
Orchid builds on decades of research by geneticists, who have pinpointed single-gene causes of thousands of diseases. We’re excited to bring this information to parents at the earliest stage possible so they can make informed choices about their embryos.
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@OrchidInc
Orchid
8 months
Thank you to @kevinhartz and @juliahartz , early customers and early investors in Orchid. They have helped pave the way for the most high resolution embryo report on the planet, that will help them and countless other families give their children a healthy start to life.
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@OrchidInc
Orchid
8 months
As of today, IVF centers in the US can offer Orchid as an option to their patients. To use Orchid, talk to your doctor at your fertility center. Or sign up for access on our website, and our team can direct you to one of our preferred IVF centers.
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@OrchidInc
Orchid
3 years
Couples with family members who suffer from diseases like schizophrenia are so consumed with fear around passing on the condition that some forgo having children at all. We’re here to change that.
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@OrchidInc
Orchid
4 years
#COVID video consults with an emergency medicine physician can be booked here-
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@OrchidInc
Orchid
5 months
@Noahpinion shares his thoughts on what makes dating so tough - the fact that successful people are just so busy.
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@OrchidInc
Orchid
3 months
Orchid's whole genome embryo reports read 100x more data than traditional tests. But what does that extra coverage get you? Watch this video to learn more!
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@OrchidInc
Orchid
3 years
Our reports detect if a couple can pass on an elevated genetic predisposition to their future children for 10 top diseases: heart disease, stroke, atrial fibrillation, schizophrenia, Alzheimer's Disease, breast cancer, prostate cancer, type 2 diabetes, type 1 diabetes, and IBD
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@OrchidInc
Orchid
3 years
We believe prospective parents deserve access to modern genetics so they can make informed choices about how to protect the health of their family. Here's what families impacted by schizophrenia have to say about screening
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@OrchidInc
Orchid
8 months
We're grateful to our world-class team of advisors, our investors, and partners who believe in our vision. Your support has made this milestone possible, here’s to people having more data and confidence as they build their families. Learn more today:
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@OrchidInc
Orchid
8 months
Another Orchid patient story! Thank you to @arjie and Julie, early customers of Orchid, whose story was told in our CNBC profile last week. They chose to use Orchid after their IVF clinic discovered they are both carriers for non-syndromic hearing loss, which can result in a
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@OrchidInc
Orchid
3 years
Clover ( @VivekGaripalli ), Eventbrite ( @kevinhartz ), Flatiron ( @natsturner ), Oscar ( @mariots ), Stellar ( @JedMcCaleb ) as well as institutional support from @refactor Capital, @villageglobal , @DayOneVC , @OliveWang839 , @varsharao and more.
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@OrchidInc
Orchid
3 years
Existing genetic tests only sequence less than 2% of a single partner’s genome. In contrast, Orchid reads 100% of both partner’s genomes. We don’t cut corners and are here to provide the most comprehensive results available.
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@OrchidInc
Orchid
8 months
Thank you to @_vltn , an early customer of Orchid and founder of her own start-up company. Her early adoption of Orchid has helped us build a better product that will in turn help reduce genetic risks for babies in the future. “With Orchid, I feel I’ve done the most responsible
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@OrchidInc
Orchid
3 years
Over the past year, we’ve brought together leaders in fertility, genomics, and reproductive health, to build a first-of-its-kind ultra high resolution genetic testing system that allows couples to measure and mitigate genetic risk for the diseases that matter to most of us.
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@OrchidInc
Orchid
3 years
Have healthy babies. Get early access to Orchid.
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@OrchidInc
Orchid
3 months
We are thrilled to share that our CEO @noor_siddiqui_ has been selected as a 2024 @aspenideas Health Fellow! We look forward to her meaningful conversations about whole genome embryo screening, and how it can help parents mitigate risk for genetic disease for their children.
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@OrchidInc
Orchid
3 years
Thank you to the exceptional group of operators and investors that are helping us build that future. We’ve raised a $4.6M seed round from the founders 23andMe @annewoj23 , Coinbase ( @brian_armstrong , @FEhrsam ), Counsyl ( @balajis )
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@OrchidInc
Orchid
8 months
A hearty thank you to our investors. Every single one of you has made a huge difference, and has helped parents give their babies a chance at a healthy start: @zalzally @brian_armstrong @JedMcCaleb @eriktorenberg @mashadrokova @OliveWang839 @chadbyers
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@OrchidInc
Orchid
6 months
Sharing the newest episode of Conceivables with @noor_siddiqui_ , with the incomparable George Church. Dr. Church is a legend in genomics: He published the first genomic sequencing method in 1984 and has been regularly making foundational contributions to the field ever since.
@noor_siddiqui_
Noor Siddiqui
6 months
Honored to host George Church, PhD - Professor of Genetics at Harvard Medical School & pioneer in genomics on ep2 of pod! "I think the trend is going to be towards everybody getting IVF as the main way of having babies. I think that's a plausible future." @geochurch
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@OrchidInc
Orchid
8 months
Parents can be more confident building their families thanks to you: @jharinstein @stephxsher @teflonblondie @saranormous @lucy_guo @fidjissimo and many, many more!
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@OrchidInc
Orchid
3 years
Unfortunately, the diseases that matter to most of us aren’t so “simple”. For most diseases, there isn’t a single genetic cause but rather millions of variants across the genome collectively driving disease risk.
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@OrchidInc
Orchid
3 years
Life is short, do work that matters at Orchid We’re a small team of optimistic builders working on Orchid because we believe helping couples have healthy babies will be the most significant work of our lives.
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@OrchidInc
Orchid
3 years
Existing genetic tests only allow parents to screen for the super rare events with a 1 in 10,000 or even 1 in a million chance of happening. These diseases follow a “simple” inheritance pattern and are caused by single gene mutations.
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@OrchidInc
Orchid
3 years
Existing genetic tests aren’t actionable. In contrast, Orchid allows couples to understand if they are at elevated genetic risk before they conceive.
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@OrchidInc
Orchid
3 years
Orchid is deeply committed to our technology being made available to every family that stands to benefit. If you could benefit but can't afford testing, please fill out this application for financial assistance and we’ll see how we can help.
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@OrchidInc
Orchid
3 years
Orchid’s Couple Report is available now. ‍You can join the waitlist here: Orchid’s Couple Report is designed for all couples looking to go into their pregnancy prepared and informed about how to optimize health for their family.
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@OrchidInc
Orchid
3 years
Orchid can quantify risk for these “complex” diseases that matter to most of us - 1 in 5 Americans is affected by the diseases we screen for.
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@OrchidInc
Orchid
3 years
It comes with three reports – one detailing a future child’s risk and one outlining each partner’s individual risk. You’re not alone – every report is reviewed by a board certified genetic counselor before delivery to you.
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@OrchidInc
Orchid
3 years
April was a good month for Orchid and a great month for health tech. Congratulations to the firms that also raised the Seed funding this April-we're thrilled to be in such good company. @vizgen_inc @openloophealth @staffcircle @peachypay
@GrowthLists
Growth List
3 years
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@OrchidInc
Orchid
5 months
After the group discusses a key issue, that some men don’t recognize their desirability outside of financial contributions, @stephxsher shares her advice to normalize complimenting male partners for other kind things they bring to the relationship
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@OrchidInc
Orchid
5 months
Amazing thread from @bpodgursky , Head of Engineering at Orchid, about his personal PGT experience and why he's so driven by what we're building at Orchid
@bpodgursky
Ben Podgursky 🧬 👶
5 months
🧵 I want to talk about why I'm personally driven by what we're building at @OrchidInc . Our 3yo was born via IVF. We're lucky — we had a healthy child — but looking back at the PGT data, it's clear that we lost viable embryos due to poor-quality PGT-A. I'll show why. (1/15)
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@OrchidInc
Orchid
3 months
Mitigate risk for hundreds of genetic diseases *before* your pregnancy even begins. Embryo reports mean you can be proactive, prepared, and informed. The greatest gift is a healthy life. Honored to serve so many thoughtful parents. Thank you Wired for the deep dive on our
@WiredMiddleEast
WIRED Middle East
3 months
Out of 140 million babies born each year, 8 million are genetically vulnerable to a range of diseases. Can we beat these odds knowing what we know at birth? Click to read more.
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@OrchidInc
Orchid
3 years
We’re honored to give parents the ability to change the trajectory of their children’s life – toward health, and away from diseases that have burdened their family for generations.
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@OrchidInc
Orchid
3 years
We’re excited to deliver on the promise of precision medicine. The goal of genomic medicine for over three decades has finally been realized – we can now measure genetic susceptibility to the diseases that matter most.
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@OrchidInc
Orchid
4 years
@GeriOncMD I’m so sorry. What a testament to your compassion as this patients physician during this hard time. Thank you for your heartfelt care
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@OrchidInc
Orchid
3 years
Later this year, we’ll roll out Orchid’s Embryo Report to help prioritize embryos based on mitigating disease risk for couples in the IVF process.
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@OrchidInc
Orchid
4 years
Physician-scientist @DrCindyMDuke weighs in on how to navigate COVID-19's impact on your IVF and egg freezing plans. Thurs April 23rd @ 3pm PST / 6pm EST Join us and bring your questions! Register here:
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@OrchidInc
Orchid
3 years
Here’s to a future where every couple that wants to conceive, gets to do so with confidence. Here’s to a future where fewer of our children suffer from the same diseases that affected their parents. Here’s to a future where fewer lives are hijacked by health issues.
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@OrchidInc
Orchid
3 years
The Couple Report is a simple at-home saliva test
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@OrchidInc
Orchid
3 years
Couples then have the option to quantify genetic risk present in each embryo, and transfer the lowest risk embryo that is most likely to lead to a healthy, normal pregnancy.
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@OrchidInc
Orchid
5 months
@kevinhartz and @juliahartz talk about using Orchid as they consider becoming parents again, more than a decade after their daughters were born - “Orchid gave us the confidence that we could be parents again. Before we thought that would be over for us, so it’s really
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@OrchidInc
Orchid
5 months
@Noahpinion closes us out with the epic advice to simply become more powerful than what stands in your way. Be more brave!
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@OrchidInc
Orchid
4 years
Ask an OBGYN: Is it safe to try to conceive during a pandemic? If a pregnant woman contracts COVID-19, can it trigger a preterm birth? Hospital vs. home based delivery? How would you weigh the risks? Today at 3pm Pacific / 6pm Eastern! Join us :)
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@OrchidInc
Orchid
3 months
They share their thoughts on criticism they’ve received for their choice to use IVF for their family: “There’s one goal here and it’s to have a healthy baby. There should be nothing else that gets in the way of that.”
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@OrchidInc
Orchid
3 months
Sadly, between 10 and 20% of known pregnancies end in a miscarriage. @roohijeelanimd walks through the causes of miscarriages:
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@OrchidInc
Orchid
3 years
Advanced genetic testing can now see if the genetic component to heart disease can be quantified for you and your family. See how you can better protect your family from the leading global cause of death through modern genetics. ❤️
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@OrchidInc
Orchid
6 months
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@OrchidInc
Orchid
5 months
Check out @bpodgursky 's explainer of Orchid's risk calculator that illustrates how polygenic embryo screening might reduce risk of chronic diseases
@bpodgursky
Ben Podgursky 🧬 👶
5 months
We talk to many prospective parents who want to quantify how much polygenic embryo screening can reduce the risk of a given disease — usually a disease which seriously affects themselves or a close relative. So we built a tool to help parents answer that question.
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@OrchidInc
Orchid
3 months
@_vltn 's advice for people considering starting a company: “Talk to a lot of people, and rely on the cold responses you get from them. If your ideal customer is not responding ‘Oh my gosh, this actually really does suck’, think very carefully about the space you’re in.”
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@OrchidInc
Orchid
4 years
Join us at 3pm Pacific tomorrow via webinar: A board certified OBGYN weighs in on how COVID-19 impacts your conception, pregnancy, and delivery plans.
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@OrchidInc
Orchid
7 months
We are thrilled to announce Noor Siddiqui, CEO of Orchid, has launched a podcast to discuss technologies and ideas that will fundamentally impact our world. The first conversation with @rohanseth is live on Apple Podcasts and Spotify, now!
@noor_siddiqui_
Noor Siddiqui
7 months
In our first episode, @rohanseth talks about the incredible lengths he went to find a diagnosis and treatment plan for his daughter, Lydia, after she started having seizures and ended up in the NICU in her first three weeks of life
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@OrchidInc
Orchid
6 months
@noor_siddiqui_ George discusses what makes biotech companies successful in the transition from the lab to the market, what excites him about whole genome sequencing and how embryo screening and IVF might one day be the default way of having children.
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@OrchidInc
Orchid
2 months
Honored to have you on the team! 🚀🧬🍼
@zaaisvanzyl
Zaais van Zyl
3 months
life update: joined @OrchidInc as a software engineer 🧬🚀
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@OrchidInc
Orchid
5 months
Sharing this week’s episode of Conceivable with Noor featuring Tim Urban, author of blog @waitbutwhy and book What’s Our Problem. Noor and Tim have a wide ranging conversation about his Life Calendar, procrastination, and his new book.
@noor_siddiqui_
Noor Siddiqui
5 months
The future is going to be weird. People are going to have AI spouses fulfilling their emotional needs in ways we only thought humans could. credit: @waitbutwhy
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@OrchidInc
Orchid
3 years
We're focused on measuring and mitigating disease risk. The Couple Report helps future parents understand their risks. Meaningful risk reduction is possible via prioritization.
@ShaiCarmi
Shai Carmi
3 years
@bpasaniuc @hjpimentel Thanks Bogdan. BTW, our recent preprint shows that there is potential for meaningful risk reduction (under some conditions - screening for one disease, >=5 embryos). But the ethical/social issues (+pleiotropic risk) should still be carefully considered.
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@OrchidInc
Orchid
3 years
Did you know that most genetic tests sequence <2% of your genome? It's true. But Orchid sequences 100% of both you and your partner's genomes—get early access now.
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@OrchidInc
Orchid
5 months
The newest episode of Conceivable with Noor features tech investor @stephxsher and blogger @Noahpinion where they discuss one of the world’s hardest problems… modern dating!
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@OrchidInc
Orchid
6 months
Babies are amazing
@elonmusk
Elon Musk
6 months
Ice cream is amazing
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@OrchidInc
Orchid
5 months
The newest ep of Conceivable with Noor features Barry Behr, a legendary embryologist and leading figure in IVF labs. With Alabama’s court ruling on IVF embryos last week, it’s critical to understand, highlight, and celebrate the work of fertility practitioners like Barry.
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@OrchidInc
Orchid
3 months
We are thrilled to announce Orchid's newest additions to our Medical and Scientific Advisory Board, @DrCooperREI_IVF @roohijeelanimd and @JerryLanchbury . We are honored to be advised by such distinguished clinical and genetics leaders, and look forward to partnering together
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@OrchidInc
Orchid
6 months
Sharing the latest episode of Conceivable with Noor featuring economist Robin Hanson. Robin discusses the sharp declines in fertility rates, the cultural drivers of these declines, and the impact fertility decline will have on our global economy.
@noor_siddiqui_
Noor Siddiqui
6 months
the biggest threat to civilization is fertility collapse ep3 w/ @robinhanson , on drivers: long, inflexible career paths, gender equality, disintegrated family structure - less grandparent support, higher parenting effort... & more...
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@OrchidInc
Orchid
3 years
Schizophrenia is often misunderstood. That's why we made an Orchid Guide all about schizophrenia & its impact on individuals and families.
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@OrchidInc
Orchid
3 years
What’s a genome? Learn more from @genome_gov ’s “A Brief Guide to Genomics.”
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@OrchidInc
Orchid
3 months
Even pregnancies that look viable can end in miscarriage. @roohijeelanimd to patients: “It’s not your fault. A “perfect” embryo doesn’t mean it functions perfectly. It can be chromosomally normal, but doesn't mean it implanted right or divided right. It has a lot of work to do.”
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@OrchidInc
Orchid
3 years
An exciting future where your own eggs can be created from your skin cells, avoiding the need for an egg retrieval during IVF
@MatttBuckley
Matt Buckley
3 years
A nice progress overview of in vitro gametogenesis, an area of bio research that will have a massive impact on our species. Still so underrated! From new excellent review out of the Hayashi lab.
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@OrchidInc
Orchid
8 months
@clairlemon We're thrilled to hear that, and we're here to provide that peace of mind should you decide to expand your family. Wishing continued health and happiness to you and your children!
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@OrchidInc
Orchid
3 months
@noor_siddiqui_ on why embryo screening is so important to her personally, as a member of the South Asian community: As a South Asian herself, Noor confirmed that “we [the South Asian community] have much higher rates of heart attacks and diabetes.” After tracing the genetic
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@OrchidInc
Orchid
3 years
Actionable, clear results. Get early access.
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@OrchidInc
Orchid
3 months
@_vltn is excited that genome sequencing is becoming more accessible: “It used to cost $100M to sequence the human genome. Hopefully in a few years, maybe it costs tens of dollars, and is accessible to as many people as possible so they can have children and healthy lives.”
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@OrchidInc
Orchid
4 years
Thinking of having kids? What if you could find out about your future child’s potential health risks and do something about that ahead of time? Here’s what you need to know about what genetic testing can tell you & how to turn insights into action.
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@OrchidInc
Orchid
3 months
We also had the pleasure of hosting @DrCooperREI_IVF on Conceivable with Noor, where she talks about how exciting it is that whole genome embryo screening gives clinicians and parents more information to start answering unknown aspects of fertility
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@OrchidInc
Orchid
3 months
New Conceivable with Noor episode: @SchramIAm and Aimee, proud parents of Indie, talk about their choice to use IVF and genetic screening to mitigate Indie’s risk of hemophilia, a condition that runs in Aimee’s family, and their experience diagnosing and treating Indy for PRRT2.
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@OrchidInc
Orchid
3 months
We're also thrilled to announce @DrCooperREI_IVF has joined our Medical Advisory Board! “Orchid is empowering parents like never before. Their whole genome embryo reports screen for hundreds of conditions, and shifts us from just reacting to medical issues to proactively
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@OrchidInc
Orchid
3 years
Genetic testing doesn't have to be invasive or confusing. Let Christina Ren, CGC walk you through the ultimate guide to genetic testing before pregnancy.
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