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Nature Reviews Gastroenterology & Hepatology

@NatRevGastroHep

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We publish #gastroenterology & #hepatology Reviews and opinion. #GastroEdPick selections by the Editors: Katrina, Jordan & Eleni | #medtwitter | #sciencetwitter

London, UK
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@NatRevGastroHep
Nature Reviews Gastroenterology & Hepatology
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22 days
Our JULY ISSUE is live! Pouchitis, cell senescence & liver disease, bile acids, liver fibrosis, and much more!
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@NatRevGastroHep
Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
7 months
NEW! This REVIEW examines how the maternal gut #microbiome in pregnancy influences the developing immune system
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2 years
NEW! REVIEW | The metabolic nature of inflammatory bowel diseases #IBD #Crohns #colitis
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4 years
New content online: Cholangiocarcinoma 2020: the next horizon in mechanisms and management
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5 months
New content online: Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota–gut–brain axis
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7 years
Popular this week - this REVIEW on gut #microbiota & #IBD : causation or correlation?
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7 months
New content online: Fermented foods and gastrointestinal health: underlying mechanisms
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2 years
From our current issue, this REVIEW describes the mechanisms of mucosal healing and how they might be altered in #IBD and discusses potential therapeutic approaches to promote mucosal healing and regeneration
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1 year
New content online: Macrophages in intestinal homeostasis and inflammatory bowel disease
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2 months
New content online: Mechanisms of metastatic colorectal cancer
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New content online: The metabolic nature of inflammatory bowel diseases
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7 months
New content online: The maternal gut microbiome in pregnancy: implications for the developing immune system
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5 months
New content online: Ultra-processed foods and food additives in gut health and disease
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6 months
NEW! This Figure shows an overview of glucose metabolic pathways in the hepatocyte. Find out more about hepatic glucose metabolism in the steatotic liver here #NAFLD #MASLD
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11 months
New content online: The intersection between alcohol-related liver disease and nonalcoholic fatty liver disease
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2 years
New content online: The role of goblet cells and mucus in intestinal homeostasis
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4 years
It's #WorldMicrobiomeDay today and this year the theme is diversity. There is certainly a diverse #microbiota in our guts, which can be influenced by food. Read more in this REVIEW ->
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2 years
New content online: The many means of conversation between the brain and the gut
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2 years
New content online: Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?
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3 months
Fermented foods have gained popularity owing to their health-promoting potential - this REVIEW discusses the benefits of #fermentedfoods in gut health and disease, and how specific microbes, food components and bioactive compounds exert their effects
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3 years
REVIEW | Early detection of pancreatic cancer using DNA-based molecular approaches
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3 years
REVIEW | #Metabolomics and lipidomics in #NAFLD : biomarkers and non-invasive diagnostic tests
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2 years
Various goblet cells have differing roles in the adult small and large #intestine , find out more in this REVIEW
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7 months
New content online: A new era in obesity management
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3 years
New content online: Gut feelings: mechanosensing in the gastrointestinal tract
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3 years
NEW! REVIEW | #Metabolomics and lipidomics in #NAFLD : biomarkers and non-invasive diagnostic tests #fattyliver
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4 years
REVIEW | Modern therapeutic approaches for the treatment of malignant liver tumours
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3 years
#TBT REVIEW | You are what you eat: diet, health and the gut #microbiota
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7 years
Check out this #NatureResearch web collection on the #gut - #brain axis. Neuroimmune, #microbiota & more! #neurogastro
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New content online: Gut microbiota in overweight and obesity: crosstalk with adipose tissue
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7 months
New content online: Neutrophils: from IBD to the gut microbiota
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7 years
This Review explores the role of diet, microbes & their metabolites in #coloncancer #CRC #WorldCancerDay
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3 years
New content online: Cell death in pancreatic cancer: from pathogenesis to therapy
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2 years
NEW THIS WEEK! REVIEW | Gut immune cell trafficking: inter-organ communication and immune-mediated #inflammation
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5 years
NEW REVIEW! | The role of short-chain fatty acids in #microbiota –gut–brain communication #gutbrainaxis #microbiome
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7 months
New content online: Pathophysiology of gastro-oesophageal reflux disease: implications for diagnosis and management
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2 years
NEW! This REVIEW explores the mechanisms of mucosal healing and its potential in treating inflammatory bowel disease without immunosuppression #IBD #Crohns #Colitis
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4 years
No.7 in our top10 articles that grabbed your attention (according to Altmetrics) - this REVIEW on gut #microbiota metabolites as key actors in inflammatory bowel disease #IBD
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3 years
Best of 2021 - ALTMETRICS no.5 is this REVIEW on Dietary carbohydrates and fats in nonalcoholic fatty liver disease By Yki-Jarvinen, Luukkonen, Hodson & @TheMooreLab Read-only link #MAFLD #NAFLD #fattyliver
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2 years
New content online: Dietary management of adults with IBD — the emerging role of dietary therapy
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3 years
What is a #postbiotic ? NEW CONSENSUS STATEMENT from @ISAPPscience on the definition and scope of the term #openaccess
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3 months
#MASLD ( #NAFLD ) & alcohol-related liver disease share pathophysiological features and are leading causes of chronic liver disease worldwide Find out more about their intersection & management in this REVIEW #WorldLiverDay
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3 months
REVIEW | Lifestyle interventions in #NAFLD / #MASLD
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4 years
REVIEW | Modern therapeutic approaches for the treatment of malignant liver tumours
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2 years
NEW! REVIEW | The gut #microbiome as a modulator of healthy #ageing #microbiota
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4 years
NEW! #NewsandViews From #NAFLD to #MAFLD : when pathophysiology succeeds. Herbert Tilg & @MariaEffenberg1 discuss the proposed name change to MAFLD - metabolic associated fatty liver disease
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3 years
📢Out now! This new Consensus Statement on Advancing the global public health agenda for #NAFLD FREE Led by @JVLazarus & an international list of experts, the article aims to put NAFLD in the NCD spotlight @EASL_ilf #fattyliver #MAFLD
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5 years
NEW online! Nonalcoholic #fattyliver disease ( #NAFLD ) has become the most common form of chronic liver disease in children and adolescents. This REVIEW discusses the latest knowledge of epidemiology, pathogenesis & management #obesity
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2 years
New content online: Enteric neurons and gut homeostasis
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2 months
Seen at #DDW2024 - this figure from a review on #depression and anxiety in #IBD #gastropsych
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5 months
Seen at #ECCO24 #ECCO2024 this Figure on potential adverse effects of JAK inhibition for #IBD Paper here: Free to read
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2 years
#TBT REVIEW | #Metabolomics and lipidomics in #NAFLD : biomarkers and non-invasive diagnostic tests
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3 years
NEW! #ResearchHighlight GUT #MICROBIOTA #Microbiome -targeted diets that alter immune status
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3 years
New content online: The promise of the gut microbiome as part of individualized treatment strategies
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5 years
REVIEW | The role of #diet in the aetiopathogenesis of inflammatory bowel disease #IBD #CrohnsDisease #colitis
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5 months
New content online: Effects of dietary fibre on metabolic health and obesity
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3 years
NEW! #NewsandViews GUT MICROBIOTA | The gut #microbiome in feast and famine
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2 months
Out for #DDW2024 @DanielDickstein & colleagues review pleasurable and problematic receptive anal intercourse in #gastrointestinal disease & cancer - the disease itself & its management can affect RAI and it’s important to counsel patients on sexual health
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8 days
#Inflammation and #fibrosis are closely linked in chronic liver diseases. This REVIEW discusses how immune cell recruitment and wound healing processes can lead to non-functional scar tissue, potentially causing organ failure
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11 months
New content online: The intestine as an endocrine organ and the role of gut hormones in metabolic regulation
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3 years
REVIEW | Utilizing the gut #microbiome in decompensated #cirrhosis and acute-on-chronic liver failure This Figure summarises strategies to target the gut #microbiota in cirrhosis
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3 years
#TBT REVIEW | Brain–gut– #microbiome interactions in #obesity and food addiction
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5 years
NEW COMMENT arguing that now is the time tor re-examine the definition of #NAFLD - the vast majority of those with NAFLD do not develop clinically significant liver disease & the most frequent individual cause of death in those with NAFLD is #cardiovasculardisease
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10 months
Our OCTOBER FOCUS ISSUE ON LIVER FIBROSIS is live! Liver inflammation and cellular stress in fibrosis, HSCs and liver cancer, antifibrotic therapeutic strategies, and much more! #livertwitter #livercancer
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With rising #obesity rates, #NASH -related #hepatocellularcarcinoma (HCC) is becoming more prevalent. This REVIEW provides an in-depth look at the mechanisms driving NASH-HCC and discusses tailored therapeutic approaches #MASH #livercancer
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2 years
NEW! REVIEW #Microbiome risk profiles as biomarkers for inflammatory and #metabolic disorders
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3 years
Best of 2021 - CITATIONS No.4 is this REVIEW on Advances in #immunotherapy for #hepatocellularcarcinoma Read-only link #livercancer
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3 years
New content online: The role of oral bacteria in inflammatory bowel disease
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2 years
AUGUST ISSUE | REVIEW Attaining mucosal healing without immunosuppression is an attractive option for the treatment of #IBD . This Review describes the mechanisms of mucosal healing and how they might be altered in IBD
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3 years
#TBT REVIEW | #Circadian clocks in the digestive system
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2 years
#TBT REVIEW The complex link between #NAFLD and type 2 #diabetes mellitus — mechanisms and treatments
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3 years
New content online: Location is important: differentiation between ileal and colonic Crohn’s disease
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3 years
#TBT REVIEW | The gut #mycobiota : insights into analysis, environmental interactions and role in gastrointestinal diseases #fungi #microbiota #microbiome
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3 years
New content online: IgG4-related diseases of the digestive tract
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2 years
#Obesity , #diabetes & #NAFLD can coexist, find out more in this REVIEW on the complex links between NAFLD & type 2 diabetes mellitus #worldobesityday
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3 months
New content online: Spatial genomics: mapping human steatotic liver disease
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2 years
New content online: Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms
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4 years
New Review online ICYMI | Here, the authors summarize therapies for the treatment of malignant #liver tumours, focusing on surgical & ablative approaches & how they align with therapies such as anticancer drugs or radiotherapy. Find it here: #LiverCancer
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1 year
New content online: Lifestyle interventions in nonalcoholic fatty liver disease
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2 years
NEW! REVIEW on the role of bile acids and their receptors in gastrointestinal and hepatic pathophysiology
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4 years
New content online: Viscera affectum anno: the gut beyond eating behaviours
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4 months
ILC3s orchestrate tissue physiology and immune tolerance in the gut Check out this new REVIEW on group 3 innate lymphoid cells in intestinal health and disease
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5 years
Long-term adverse events of proton-pump inhibitors being debated at #UEGweek #UEGW2019 - Savarino (myth) vs Fass (reality). The evidence on complications & PPIs was discussed in this review from 2017
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4 years
GUT–BRAIN AXIS IN 2020 | Diego Bohorquez discusses #GutBrain biology in 2020 & how 3 remarkable studies have expanded our knowledge on how the #gut makes sense of its environment to guide brain functions & behaviors beyond food #YearInReview @gutbrains
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7 years
Great session on dietary modulation of the #GutMicrobiota Are they ready for use as a clinical tool though? #DDW17
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3 months
From our April issue, this REVIEW discusses the pathophysiology of gastro-oesophageal reflux disease and the implications for diagnosis and management, different GERD phenotypes have different degrees of reflux & severity of symptoms #GORD #GERD #reflux
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1 year
New content online: A Roadmap for the Human Gut Cell Atlas
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5 years
Primary biliary cholangitis (PBC) is a chronic, inflammatory & cholestatic liver disease with a variable rate of progression towards biliary #cirrhosis . This REVIEW highlights new insights into pathogenesis & potential therapeutic targets
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REVIEW | IL-12 and IL-23 pathway inhibition in inflammatory bowel disease #IBD #Crohns #colitis
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ICYMI | The therapeutic pipeline for #NASH is expanding as insights into pathophysiology are gained, this REVIEW summarises progress in the development of NASH therapies, current & ongoing trials, and potential challenges #NAFLD #fattyliver
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NEW! REVIEW Benign liver tumours: understanding molecular physiology to adapt clinical management By @NaultJc @valerie_paradis @maximeronot @Zucmanrossi
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New content online: Cirrhosis-associated immune dysfunction
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3 years
REVIEW | The promise of the gut #microbiome as part of individualized treatment strategies
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3 months
This Figure shows the molecular mechanisms & metabolites produced by the gut #microbiota that act on receptors in the intestine or white and brown #adiposetissue Find out more in this REVIEW
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3 months
This Figure shows gut–liver axis barriers and anatomical connections Find out more in this REVIEW about the gut-liver axis
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2 years
New content online: Microbiome risk profiles as biomarkers for inflammatory and metabolic disorders
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@NatRevGastroHep
3 months
New content online: Artificial intelligence in liver cancer — new tools for research and patient management
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@NatRevGastroHep
Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
4 years
Check out this COLLECTION on diet, #microbiome & homeostasis from @NatRevGastroHep , @NatRevImmunol & @NatureRevMicro
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@NatRevGastroHep
Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
3 years
#TBT REVIEW | Therapeutic pipeline in nonalcoholic steatohepatitis #NAFLD #NASH #fattyliver
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@NatRevGastroHep
Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
2 months
Seen at #DDW2024 this figure from a review by Seguella & Gulbransen on enteric glial biology
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@NatRevGastroHep
Nature Reviews Gastroenterology & Hepatology
@NatRevGastroHep
5 years
Cholangiocytes, the epithelial cells lining the intrahepatic and extrahepatic bile ducts, are highly specialized cells. This state-of-the-art REVIEW provides an overview of #cholangiocyte pathobiology
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