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Nature Rev Immunol

@NatRevImmunol

8 days

You can now request a free copy of the poster from our sponsor @STEMCELLTech using the following link:

Nature Rev Immunol

@NatRevImmunol

1 month

Rational combination of cancer therapies with PD1 axis blockade New poster by @d_peeper & @ThommenDaniela with our pals @NatureRevCancer looking at how therapies can be combined in a rational manner to provide cooperative or synergistic benefit

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Mechanisms of antibody-dependent enhancement of infectious disease

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Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

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Endothelial dysfunction and immunothrombosis as key pathogenic mechanisms in COVID-19

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NEW Review: The roles of extracellular vesicles in the immune system by @EditBuzas @semmelweishu including roles of #EVs in innate and adaptive immunity, and potential use for diagnosis and therapy #extracellularvesicles #exosomes

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Location matters: mapping antigen receptors within tissues

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'A guide to vaccinology: from basic principles to new developments' Andrew Pollard & Else Bijker @UniofOxford @OxfordVacGroup "an introductory overview of vaccines, immunization and related issues to inform a broad scientific audience" #VaccinesWork

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Complement as a target in COVID-19?

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Engineering IL-2 for immunotherapy of autoimmunity and cancer

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The effect of physical exercise on anticancer immunity

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Fibroblasts as immune regulators in infection, inflammation and cancer

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COVID-19 vaccines: modes of immune activation and future challenges

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The OrganiX microfluidic system to recreate the complex tumour microenvironment

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New: Our current understanding of the immunology behind #LongCovid , a comprehensive Review by @Daltmann10 , Emily M. Whetlock, Siyi Liu, Deepa J. Arachchillage and @BoytonRosemary

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NEW Review: A guide to adaptive immune memory by @DonnaFarber3 @noralam_ & YoonSeung Lee provides an overview of current understanding of the phenotype, function, location, generation, maintenance and protective capacity of memory T cells and B cells

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How the immune system shapes atherosclerosis: roles of innate and adaptive immunity

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The type I interferonopathies: 10 years on

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Same yet different — how lymph node heterogeneity affects immune responses

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'The first 12 months of COVID-19: a timeline of immunological insights' by @VirusesImmunity @florian_krammer @CyrilPedia details the collaborative efforts that enabled key aspects of the immune response to SARS-CoV-2 to be reported at unprecedented speed

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Nature Rev Immunol

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6 years

Congratulations to James Allison and Tasuku Honjo #NobelPrize #cancer #immunotherapy Watch our movie (with @NatureRevCancer ) to learn how immune checkpoint therapy works:

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2 years

TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective

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The germinal centre B cell response to SARS-CoV-2

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How bile acids and the microbiota interact to shape host immunity

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Dissecting antibody-mediated protection against SARS-CoV-2

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Roles of natural killer cells in immunity to cancer, and applications to immunotherapy

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Inflammasome activation at the crux of severe COVID-19

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CD8+ T cell differentiation and dysfunction in cancer

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A guide to thymic selection of T cells

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The potential danger of suboptimal antibody responses in COVID-19

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Rethinking peripheral T cell tolerance: checkpoints across a T cell’s journey

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Regulation of immune responses by the airway epithelial cell landscape

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Nature Rev Immunol

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@DrPragyaAgarwal Oh dear. Just as well a few women broke the rules and left home to make us a vaccine...

Prof Sarah Gilbert: The woman who designed the Oxford vaccine

Prof Sarah Gilbert got to work quickly on a coronavirus vaccine in January after decades of research.

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Nature Rev Immunol

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3 years

Does the epithelial barrier hypothesis explain the increase in allergy, autoimmunity and other chronic conditions?

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Nature Rev Immunol

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3 years

Inflammation and immune dysfunction in Parkinson disease

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Nature Rev Immunol

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Cancer cell metabolism and antitumour immunity

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Nature Rev Immunol

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Human stem cell models to study host–virus interactions in the central nervous system

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Nature Rev Immunol

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The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?

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mRNA vaccine shows promise in autoimmunity

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Leukocyte trafficking to the lungs and beyond: lessons from influenza for COVID-19

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New Comment article from @VirusesImmunity and Yexin Yang on the potential danger of suboptimal antibody responses in COVID-19

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Viral targets for vaccines against COVID-19

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NEW Comment article by @VikiLovesFACS @imperialcollege 'Are COVID-19 vaccines safe in pregnancy?'

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Nature Rev Immunol

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3 years

Mucosal vaccines — fortifying the frontiers

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Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies

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T cell regeneration after immunological injury

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2 years

Mitochondrial control of inflammation

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The conneXion between sex and immune responses

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Nature Rev Immunol

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Bacterial origins of human cell-autonomous innate immune mechanisms

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Nature Rev Immunol

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The role of platelets in immune-mediated inflammatory diseases

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Memory B cells

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Nature Rev Immunol

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10 months

Role of the microbiota in response to and recovery from cancer therapy

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6 years

New Review on how circadian rhythms influence the immune system. #circadian_clock #chrono -immunotherapy

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2 years

Glomerulonephritis: immunopathogenesis and immunotherapy

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The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues

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4 years

See new Progress article from Zeyu Chen and @EJohnWherry on T cell responses in patients with COVID-19

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3 years

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

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A guide to interrogating immunometabolism

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3 years

Red blood cells join the ranks as immune sentinels

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2 years

The impact of the gut microbiome on extra-intestinal autoimmune diseases

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Nature Rev Immunol

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3 years

The role of T cells in age-related diseases

Nature Reviews Immunology - In this Review, Maria Mittelbrunn and colleagues highlight the involvement of T cells in diseases associated with ageing. In particular, the authors discuss how T cells...

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Nature Rev Immunol

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2 years

Tumours tend to disseminate early, yet metastases often take years to maifest. What determines when and where they form? @alpcorreia discusses the site specific immune barriers to metastasis in this perspective

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Nature Rev Immunol

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3 years

Immunomodulation by radiotherapy in tumour control and normal tissue toxicity

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Is IL-6 a key cytokine target for therapy in COVID-19?

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How transcription factors drive choice of the T cell fate

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Nature Rev Immunol

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3 years

Our October 2021 issue marks 20 years of Nature Reviews Immunology - see our special anniversary collection:

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Nature Rev Immunol

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Therapeutic induction of antigen-specific immune tolerance

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The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses

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Understanding COVID-19-associated coagulopathy

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The link between circulating follicular helper T cells and autoimmunity

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Sex differences in immune responses in COVID-19

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Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

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Nature Rev Immunol

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The state of complement in COVID-19

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Nature Rev Immunol

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3 years

Immune and non-immune functions of adipose tissue leukocytes

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Tumour immunotherapy: lessons from predator–prey theory

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IL-17 and IL-17-producing cells in protection versus pathology

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5 years

DAMP-sensing receptors in sterile inflammation and inflammatory diseases

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9 months

Brain regulatory T cells

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Cell death by phagocytosis

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Diversity and dynamism of IgA−microbiota interactions

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Nature Rev Immunol

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4 years

See the new Comment from Schett et al. on COVID-19: risk for cytokine targeting in chronic inflammatory diseases?

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Immune-based therapies in cardiovascular and metabolic diseases: past, present and future

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Tissue regulatory T cells: regulatory chameleons

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B cells, plasma cells and antibody repertoires in the tumour microenvironment

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Thymic development of unconventional T cells: how NKT cells, MAIT cells and γδ T cells emerge

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Bone marrow inflammation in haematological malignancies

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Integrated organ immunity: a path to a universal vaccine

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SARS-CoV-2 and HIV-1 — a tale of two vaccines

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Immunotherapy combination approaches: mechanisms, biomarkers and clinical observations

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The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases

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NEW Review of the molecular mechanisms by which short-chain fatty acids - butyrate, propionate and acetate - link diet, microbiota and immunity by @lizziemannlab @YingKaLam & Holm Uhlig

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Nature Rev Immunol

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6 years

New #Review on CD4+ T cell help in cancer, discussing the molecular nature of help signals and how they can be harnessed to improve cancer immunotherapy.

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