Great honor to be published in NEJM as PI and Author w/ these outstanding VISION InvestigatorsπTHANK YOU π to our prostate cancer patients for enrolling in our groundbreaking study.
βοΈBIG THANKS to Dr. Sartor & Dr. Morris for OUTSTANDING LEADERSHIP.
βοΈDarolutamide/Docetaxel/ADT becomes new STANDARD of CARE for newly diagnosed metastatic prostate cancer patients w/a 32.5% β¬οΈ risk of death
πAs co-Author & co-PI of ARASENS study, THANK YOU to our patients.
πJUST published in NEJMπ
@OncoAlert
Great honor to be published in the NEJM as a Principal Investigator π with these outstanding investigators.
I am PROUD our research team at Norton Cancer Institute had the 2nd HIGHEST enrolling number of patients in the United States for the development of Enfortumab Vedotin
βοΈPRACTICE changing paper in NEJM. Darolutamide, ADT & Docetaxel combo significantly improved OS. πTHANK YOU to our Research team & Patients in our trial. π Great honor to be a PI with this outstanding group of GU oncologists.
@OncoAlert
π
βοΈPractice changing NEJM paper. Stage II & Stage III Triple Negative Breast Cancer. 36 month EFS was 84.5% (95% CI [CI], 81.7 to 86.9) pembrolizumabβchemotherapy arm, as compared with 76.8% (95% CI, 72.2 to 80.7) in the placeboβchemotherapy arm.
@OncoAlert
πJust ANNOUNCED. 1st ever LAG-3 immunotherapy approved by the FDA for 1οΈβ£st line metastatic melanoma w/Nivolumab.
Congratulations to Dr. Tawbi, his co-Principal Investigators, & the melanoma study patients for their contribution to science.
@OncoAlert
βοΈ Great talk by Dr. Hope Rugo. 6οΈβ£5οΈβ£% of breast cancer patients with HR+ are HER2-low. 3οΈβ£7οΈβ£% of triple negative breast cancer patients are HER2-low.
@OncoAlert
βοΈDid you know 43% of patients with NSCLC have mutations that are targetable with APPROVED agents?
Masterful discussion by Dr. Melissa Johnson at the Masters Lecture Series with the current targetable medications to best treat our lung cancer patients .
@OncoAlert
βοΈHow to TREAT metastatic triple negative breast cancer. Dr. Gregory Vidal, Director of Breast Oncology at West Cancer Center and Regional Health Series provides an easy to follow table to help our breast cancer patients at the Masters Lecture Series.
@OncoAlert
OUTSTANDING discussion of the current landscape of HER2+ Breast Cancer by leading expert Dr. Hope Rugo at the NOSCM this morning. β€οΈ this algorithm for early disease HER2+ Breast Cancer treatments.
@OncoAlert
β Do ALL renal cell cancer patients require adjuvant Pembrolizumab after nephrectomy? Dr. Katy Beckermann provides a masterful discussion at our Masters Lecture Series.
@OncoAlert
βοΈFDA APPROVED. As co-PI of ARASENS, a BIG THANK YOUπ to our prostate cancer trial patients & families.
πCongrats to my AMAZING team at Norton Cancer Institute for enrolling the HIGHEST number of patients in the country.
π
@OncoAlert
βοΈHow to TREAT early stage Triple Negative Breast cancer. Dr. Hope Rugo shares her algorithm for medical oncologists to use in their clinical practice right away.
@OncoAlert
@hoperugo
β JUST RELEASED by
@tompowles1
@DrChoueiri
et al : Pembrolizumab as post-nephrectomy adjuvant tx for clear cell renal cell carcinoma (30-month follow-up). πDFS better w/ Pembro compared to placebo (HR 0Β·63 [95% CI 0Β·50β0Β·80]).
@OncoAlert
πclickπ
Congrats to my former Chair and mentor Dr. Jame Abraham for becoming the new Chairman of
@ClevelandClinic
Hematology/Oncology. Perfect role model. Patients LOVE him, outstanding leader, wonderful teacher, research expert. Most importantly a KIND and GREAT person.
@jamecancerdoc
We are THRILLED to present the VISION study
@ASCO
2021. As a PI and Author, we would like to THANK our prostate cancer patients for enrolling in this groundbreaking study. Thank you to leadership of Dr. Michael Morris Dr. Oliver Sartor & VISION authors .
βοΈctDNA 𧬠from Non small cell lung csncer patients suggests that the likelihood of disease relapse decreases β¬οΈ for high-risk stage II/III patients after 18 months without ctDNA detection. π―
Click π
@OncoAlert
Always GREAT to see Toni. He is always kind and generous to help junior people in the GU field. Thank you
@DrChoueiri
for connecting me to research leaders in liquid biopsy.
@ASCO
#GU23
βοΈMy good friend
@PGrivasMDPhD
and I talk about the importance of Mentorship in Oncology. We discuss people we admire such as Dr. Neeraj Agarwal and Dr. Monty Pal for being outstanding mentors. Also we discuss
@DRBakaloudiMD
journey to win the
@ConquerCancerFd
merit award.
βοΈGoose Bumps and a Standing Ovation
@ASCO
is a magical experience. β€οΈ talking to Dr.
@RamalingamMD
about his 1st patient with EGFRm over ten years ago to his plenary session yesterday.
πJoin us tonight on
@OncLive
#ASCO24
We discussed the LAURA study
βοΈGut microbiome π¦ changes can result in the development of several diseases, including prostate cancer.
β‘οΈGut-prostate axis is evaluated as a potential target π― for the treatment of prostate cancer.
#pcsm
Click β¬οΈ
@OncoAlert
βοΈPractice Changing EMBARK Trial
1οΈβ£Prostate CA w/biochem recur πPSA doubling time less than 9 months
2οΈβ£ Three armsπenzalutamide +ADT, enzalutamide, or ADT
3οΈβ£ 5 year Mets Free Surv π87% Enza+ADT, 80% Enza, 71%ADT
π
HRQoL data at
#ESMO23
@OncoAlert
THRILLED to announce our LIVE 1 day Masters Oncology meeting with LEADING cancer docs in America with updates from
@ASCO
2021 in Nashville, Tennessee. OUTSTANDING Faculty from Sarah Cannon, Vanderbilt, Brown University Cancer Center, Dana Farber, Iowa π
π‘OUTSTANDING
#ASCO23
@OncoAlert
update on βEffect on outcomes of toxicity-related dose reduction in TKI monotherapy or TKI-IO combination therapy for adv. renal cell carcinomaβ, by rising GU superstar Dr. Amanda Nizam
@AmandaNizamMD
.
@weoncologists
π
βοΈAlways FUN to catch up with these passionate
@ASCO
leaders that are blazing the trail in medical oncology.
β€οΈ their infectious enthusiasm to help cancer patients, spearhead ASCO initiatives, and inspire medical oncology trainees.
@CathyEngMD
@drdonsdizon
β‘οΈGreat to see Monty at
@ASCO
#GU23
and congratulate him on his election to
@ASCO
nominating committee. He is an outstanding mentor for his mentees and he will use the same interpersonal skills to be an outstanding leader for
@ASCO
.
β Authoritative ASH Guidelines to help our cancer patients in the prevention and treatment of DVT and PEπ
πOutstanding job by Dr. Lyman and his great team
@gary_lyman
on when to use Oral Anticoagulants π, Heparin, and Enoxaparinπ
#cancer
#VTE
#DVT
πCONGRATULATIONS to my good friend
@PGrivasMDPhD
for becoming a Full Professor
@fredhutch
@UWDeptMedicine
. VERY FORTUNATE to have worked closely with him on research & education. Petros is a SUPERSTAR scientist, STELLAR clinician, and most importantly a GREAT person.
@OncoAlert
βοΈAs a selection committee member
@OncLive
Giants of Cancer Care for close to ten years, it is w/great pleasure we celebrate 2024 inductees.
Join us as we hear stories of luminaries in oncology and their journey to prominent contributions in oncology. π
βοΈJoin me and my good friend Dr. Pedro Barata in
#Cleveland
on Saturday August 19. We will have Global leaders in GU oncology on βHow the Masters treat Kidney, Bladder, and Prostate cancersβ
@PBarataMD
@DrChoueiri
@shilpaonc
@GUONCGarciaJA
πClick here π
β‘οΈSome renal cell cancer patients that receive adjuvant Pembro based on KEYNOTE-564 may ALREADY be CURED but are OVER treated w/risk of developing toxicity.
Is there a role for MRD to find these patients?
Dr. Arnab Basu answers thisβat
@ASCO
#GU23
π
βοΈWe are honored to have Dr. Navneet Majhail, Deputy Physician-in-Chief of Blood Cancers
@SarahCannonDocs
and President of
@ASTCT
β19-20 give a Keynote on CAR-T cell and cellular therapies at our How the Masters Treat meeting.
πJoin us tomorrow π
Dear Pathologists,
We were in a room the size of an aircraft hangar w/thousands of oncologists doing a standing ovation.
Now at EVERY breast tumor board you will have FIERCE debates on HER2 IHC 1+ vs IHC 0+. Progress is coming.
Good luck,
Chandler, Yan, and Mark
#ASCO22
βοΈOutstanding discussion of data in metastatic hormone sensitive prostate cancer since 2014.
Click below to watch LIVE now
π
#UromigosLive
@OncoAlert
βοΈWhat an OUTSTANDING GU oncology roundtable. We discussed non clear cell RCC, 1st line metastatic urothelial cancer, and role of PARP inhibitors for mCRPC. Thank you Jorge, Toni, Shilpa, Pedro, and Albert for a great session.
β‘οΈGreat honor to co-host a GU medical meeting for oncologists with Dr. David Aggen from
@MSKCancerCenter
. Really enjoyed working together as a team and getting to know each other. We are both alums from
@UofIllinois
. Looking forward to collaborating on future projects
βοΈHow to treat metastatic Urothelial Cancers in 2022.
Leading genitourinary oncologist Dr
@PGrivasMDPhD
gives us an algorithm for medical oncologists to follow in their medical practice next week.
@OncoAlert
β‘οΈ Just RELEASED NEJM: Ph 3 trial Rucaparib mCRPC patients w/BRCA1, BRCA2, ATM after 2nd gen ARPI.
β 62 mo rPFS 11.2 mo vs 6.4 mo(Ruc vs control) HR 0.50; ITT group(10.2 mo vs 6.4 mo, HR, 0.61)
β ATM rPFS (8.1 Mo vs 6.8 mo)
π
@OncoAlert
@ASCO
#GU23
Very FIRST CT was performed 50 years in 1971 and it picked up a brain mass. Great article today in the NEJM The CT Scan after 50 years β Continuity and Change | NEJM
βοΈOUTSTANDING Update by my friend
@DrChoueiri
at the International Congress on Immunotherapy today. Highlights includeπ
1β£His 1st line flow chart for metastatic renal cell
2β£KM curve w/IPI and Nivo for Sarcomatoid mRCC.
#StandardOfCare
#GoToICIC
#Immunotherapy
@OncoAlert
βοΈHow do the LEADING GU oncologists treat Bladder and Renal Cell Cancers in 2022?
Join us this Saturday virtually
Register for FREE π
Dr. Petros Grivas and Dr. Tian Zhang provide EXPERT advice w/Q&A on the Masters Lecture Series.
#Gu22
βοΈ How to sequence 1st line Stage IV ER+ positive breast cancer for patients after Destiny-Breast06 at
#ASCO24
. Great to talk to global leader Dr. Giuseppe Curigliano and get his expertise on
@oncodaily
πFull video π
β‘οΈSacituzumab Govitecan + Pembro for patients with metastatic urothelial cancer post platinum tx. Outstanding presentation by
@PGrivasMDPhD
and co-investigators
@ASCO
#GU23
β ORR of 41%
β CBR of 46%
β DOR 11.1 mo
β PFS 5.3 mo
@OncoAlert
π
βοΈOUTSTANDING Non-Clear Cell Renal Cell Carcinoma Update by Dr. Monty Pal.
AMAZING waterfall plot with Checkpoint Inhibitor and Cabozantinib in patients w/metastatic non clear cell renal cell.
βοΈHow do the LEADING Thoracic Oncologists treat
#LungCancer
in 2022?
Dr.Jack West and Dr. Sandip Patel discuss the latest updates with a Q&A at our Masters Lecture Series
Join me &
@PGrivasMDPhD
this Saturday virtually.
Register for FREE π
β Dr. Tanios Bekaii-Saab gives us an update on the promising role of Adagrasib in a recent NEJM and
@ASCO
Plenary session from last month at Masters Lecture Series in Seattle.
Strong dataπ
@OncoAlert
β‘οΈFascinating study. Patients that progress on Enzalutamide have very high levels of BCL-2. In this study patients that progress on Enzalutamide have Venetoclax added (a very potent BCl-2 inhibitor for 1st line treatment for CLL and AML).
@asco
#GU23
#PCa
#PosterSession
βοΈOutstanding Trophy U-01 Oral Presentation by
@PGrivasMDPhD
Combo of Sacituzumab Govitecan and Pembrolizumab demonstrated an OUTSTANDING 34% ORR with manageable toxicities. Great honor to be a part of this GU research study.
Abstractπ
@OncoAlert
We are THRILLED to have Dr. Guru Sonpavde, Director of the Bladder Cancer Program at Dana Farber Cancer Institute and Faculty at
@harvardmed
School give us a 2021
@ASCO
Bladder and Prostate Cancer LIVE update tomorrow. Join us in person in Nashville π
βοΈJUST published in NEJM.
NEW standard of Care for 2nd line relap/refrac large B-cell lymphoma patients . Axicabtagene ciloleucel led to 60% improvement in event-free survival vs Standard of Care 2nd-line chemo tx. Phase 3 ZUMA-7 trial
@OncoAlert
#ASH21
Implications of KEAP1 and TP53 (Co)mutation in Lung Adenocarcinoma: Another Bullet for Immunotherapy? - Journal of Thoracic Oncology
#LungCancer
@OncoAlert
βοΈFUN
@Uromigos
LIVE event.Thank you
@brian_rini
@tompowles1
for a STELLAR event w/GU ALL-STARS and the invitation to join you guys in beautiful Nashville.
πBladder
πProstate
πRenal Cell
@OncoAlert
π―Practice changingπEV-302 just published in NEJM for 1st line metastatic urothelial cancerπ
1οΈβ£ OS π Enfortumab vedotin-Pembro 31.5 months vs. 16.1 months chemo
2οΈβ£ PFS π12.5 months EV-P vs. 6.3 months chemo.
3οΈβ£ ORR πEV-P 67.7% vs. chemo 44.4%
β Insightful discussion by Dr.
@PBarataMD
on updated Tivozanib clinical studies at
@DAVAOnc
in Banff.
Loved the helpful table that compared TKI toxicities of drugs given for RCC.
@OncoAlert
β Thank you Dr. Winer for your 1 year of dedicated service as our outstanding ASCO President.
Great honor to introduce my mentee
@ShubhAgrawalMD
to Dr. Eric Winer at our
@ASCO
reception on his last day as President.
#ASCO23
@OncoAlert
βοΈCongratulations to Dr. John Marshall for his 2024 Giants of Cancer Care induction.
LOVED our
#ASCO24
conversation on KRASG12C and when yo you use T-DXD for Stage IV colorectal cancer patients based on the April 2024
@US_FDA
pan tumor approval for HER2 IHC 3+
@marshalj23
We
βοΈOUTSTANDING
@ASCO
Direct Miami meeting hosted by Symposium Director
@LuisERaez1
and
@MCIStrong
Education Committee. Over 350+ medical professionals in the audience. It was an honor to join the 50+ expert faculty to discuss ASCO 2022 highlights this weekend.
@OncoAlert
βοΈ Outstanding teaching case by Dr. Barata on how to treat oligometastatic renal cell cancer patients with sarcomatoid features in the checkpoint era at the New Orleans Summer Conference.
@OncoAlert