We are excited to launch BMJ’s newest specialty journal, BMJ Oncology (https://bmjoncology.bmj.com), an online-only, open-access journal dedicated to publishing the highest quality papers across the...

The impact of adverse events on patient adherence to cancer treatments is well documented. Most relationships of interest to the clinician focus on biochemical interactions between the patient,...

The impact of adverse events on patient adherence to cancer treatments is well documented. Most relationships of interest to the clinician focus on biochemical interactions between the patient,...

Oncology has a strong grounding in science. In radiation oncology, we have harnessed amazing technological advances resulting in the current state of the art linear accelerator producing high energy...

A new study by Tim J Palmer (Public Health Scotland, Glasgow, UK) and colleagues has revealed that no cases of cervical cancer have been detected in Scotland in anyone who received the human papill...

Clinical trials in recent years have become more challenging and costly to run. COVID-19 has revealed the power of huge driving forces behind research studies and how new and alternative ways of...

Long-term screening with serum prostate-specific antigen (PSA) and systematic prostate biopsies can reduce prostate cancer mortality but leads to unacceptable overdiagnosis. Over the past decade,...

The majority of the initial seminal cancer treatment trials during the 1970s and later on focused on clinical efficacy and clinician-assessed harms. Patient-reported outcome measures (PROMs) includ...

Objective To assess time trends in the inclusion of health-related quality of life (QoL) among study endpoints and in the reporting of QoL results in study publications, randomised phase III oncology...

The majority of the initial seminal cancer treatment trials during the 1970s and later on focused on clinical efficacy and clinician-assessed harms. Patient-reported outcome measures (PROMs) includ...

Objective Transgender, non-binary and intersex people are less likely to receive appropriate cancer screening for their bodies and have a higher incidence of certain cancers than cisgender people. We...

Objective The arginase inhibitor INCB001158 was evaluated for safety (primary endpoint) in locally advanced or metastatic solid tumours; pharmacokinetics, pharmacodynamics and efficacy were also...

Objective To review the efficacy and safety of low-dose versus standard-dose enzalutamide, apalutamide or darolutamide treatment for metastatic prostate cancer.Methods and analysis Keyword searches...

Long-term screening with serum prostate-specific antigen (PSA) and systematic prostate biopsies can reduce prostate cancer mortality but leads to unacceptable overdiagnosis. Over the past decade,...

Long-term screening with serum prostate-specific antigen (PSA) and systematic prostate biopsies can reduce prostate cancer mortality but leads to unacceptable overdiagnosis. Over the past decade,...

Long-term screening with serum prostate-specific antigen (PSA) and systematic prostate biopsies can reduce prostate cancer mortality but leads to unacceptable overdiagnosis. Over the past decade,...

Long-term screening with serum prostate-specific antigen (PSA) and systematic prostate biopsies can reduce prostate cancer mortality but leads to unacceptable overdiagnosis. Over the past decade,...

This cohort study evaluates whether the overall population of patients with metastatic cancer receiving care at practices with higher rates of oncologic therapy for very advanced disease experienced...

In the realm of radiotherapy, evidence-based medicine is paramount in determining clinical decisions and expected patient outcomes. Randomised control trials (RCTs) are the gold standard for evalua...

We write this editorial some 2.5 years after the first national COVID-19 lockdown was announced in the UK on 17 March 2020. We reflect on the reality of how the pandemic and the national response to...

Objective Recent studies have identified challenges facing women oncologists in Western contexts. However, similar studies in Africa have yet to be conducted. This study sought to determine the most...

Objective Transgender, non-binary and intersex people are less likely to receive appropriate cancer screening for their bodies and have a higher incidence of certain cancers than cisgender people. We...

This meta-analysis estimates the percentage and number of incident cancers attributable to infections in the US among adults and children for the most recent year cancer incidence data were available...

Oncology has a strong grounding in science. In radiation oncology, we have harnessed amazing technological advances resulting in the current state of the art linear accelerator producing high energy...

In the last two decades, a number of widely varying estimates of overdiagnosis rates in breast cancer screening have been published. The estimates of overdiagnosis, in terms of an increase in...

PURPOSE To compare effects and side effects of 6 weeks of individually dose-titrated methylphenidate or placebo on fatigue in palliative care patients with advanced cancer. METHODS This is a random...

Clinical trials in recent years have become more challenging and costly to run. COVID-19 has revealed the power of huge driving forces behind research studies and how new and alternative ways of...

We write this editorial some 2.5 years after the first national COVID-19 lockdown was announced in the UK on 17 March 2020. We reflect on the reality of how the pandemic and the national response to...

Researchers have found that a blood test alone to detect prostate cancer can be unreliable, leading to overdiagnosis and missing some cancers.

Objectives To evaluate National Comprehensive Cancer Network (NCCN) guideline recommendations for oncology drug treatments that have been granted accelerated approval, and to determine whether...

Objective To assess time trends in the inclusion of health-related quality of life (QoL) among study endpoints and in the reporting of QoL results in study publications, randomised phase III oncology...

Clinical trials in recent years have become more challenging and costly to run. COVID-19 has revealed the power of huge driving forces behind research studies and how new and alternative ways of...

We write this editorial some 2.5 years after the first national COVID-19 lockdown was announced in the UK on 17 March 2020. We reflect on the reality of how the pandemic and the national response to...

National Cancer Research Institute is closing just when we need it most The UK’s National Cancer Research Institute (NCRI) announced unexpectedly in June 2023 that it will be permanently “winding...

Objective In men with a raised prostate-specific antigen (PSA), MRI increases the detection of clinically significant cancer and reduces overdiagnosis, with fewer biopsies. MRI as a screening tool...

BMJ Oncology Editorial Board members have agreed and adhere to the BMJ Editor Roles and Responsibilities guidelines; including our Editor policy on competing interests.

Objective Although adjuvant trastuzumab-based treatment (TBT) improves survival for patients with HER2-positive early invasive breast cancer (EIBC), risk of toxicity grows as patient age increases....

Over 30 years ago, Catalona et al proposed using prostate-specific antigen (PSA) as a screening test for prostate cancer.1 Their recommendation was based on the ability of PSA to find more prostate...

This cross-sectional study evaluates the credibility of differential treatment effect claims in published phase 3 randomized clinical oncology trials published prior to 2021 according to the Instru...

Clinical trials in recent years have become more challenging and costly to run. COVID-19 has revealed the power of huge driving forces behind research studies and how new and alternative ways of...

Objective Pain is experienced by most patients with cancer and opioids are a cornerstone of management. Our objectives were (1) to identify patterns or trajectories of long-term opioid therapy (LTOT)...

In the field of general medicine, class effects, or therapeutic interchangeability, have been declared for several families of drugs including statins, calcium channel blockers and ACE inhibitors....

Objective To assess time trends in the inclusion of health-related quality of life (QoL) among study endpoints and in the reporting of QoL results in study publications, randomised phase III oncology...

Oncology has a strong grounding in science. In radiation oncology, we have harnessed amazing technological advances resulting in the current state of the art linear accelerator producing high energy...

In this issue, Monahan et al1 describe progress in addressing the lack of diagnosis of Lynch syndrome in the English National Health Service with a bold attempt to fix a leaking pathway.

Over 30 years ago, Catalona et al proposed using prostate-specific antigen (PSA) as a screening test for prostate cancer.1 Their recommendation was based on the ability of PSA to find more prostate...

In 2010, Michael Marmot and colleagues published their seminal report, Fair Society, Healthy Lives. Among the many salient conclusions, they noted, “reducing health inequalities is a matter of...

Objective To examine and interpret trends in UK cancer incidence and mortality for all cancers combined and for the most common cancer sites in adults aged 35-69 years. Design Retrospective secondary...

Objective Pragmatic methodologies, often termed rapid-learning, are being pursued that can match the pace of innovation in radiotherapy and generate evidence from the real-world treatment setting. It...

Objective To assess time trends in the inclusion of health-related quality of life (QoL) among study endpoints and in the reporting of QoL results in study publications, randomised phase III oncology...