Stephen Goldstein @stgoldst Twitter profile

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Stephen Goldstein

4 months

Inspired by @AriWRees , 2024 seems like as good a time as any to do some Salt Lake promotion about our incredible public lands and share some of my favorite places in the Wasatch foothills and canyons

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Stephen Goldstein

@stgoldst

4 years

Trump was administered an IV infusion of purified, concentrated anti-SARS-CoV-2 IgG. If he weren't positive after that something would be deeply wrong. This is not evidence of seroconversion.

Maggie Haberman

@maggieNYT

4 years

POTUS doctor says he’s symptom-free for over 24 hours and that his blood demonstrates detectable levels of antibodies compared to last week

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Stephen Goldstein

@stgoldst

4 years

There's a lot of prediction and uncertainty on the future of #SARSCoV2 in the human population. I'll do a little thread explaining why I *think* it will end up similar to the 4 "common-cold" endemic CoVs, but the time-scale on which this happens is up to us.

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Stephen Goldstein

@stgoldst

6 years

@AriFleischer You're explicitly saying Mueller should have ignored the law against basing hiring decisions based on political affiliations.

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Stephen Goldstein

@stgoldst

4 years

I want to spend a bit of time clearly laying out where #SARSCoV2 probably comes from, and how it could have ended up in Wuhan. Though it can't be ruled out there is currently no, zero evidence for a lab escape scenario while there is ample precedent for zoonotic spillover.

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Stephen Goldstein

@stgoldst

4 months

@JWLevitt Damn you got cooked

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Stephen Goldstein

@stgoldst

3 years

Glenn wants specifics, so here’s a specific lie he told. The email from Kristian to Fauci said some features of #SARSCoV2 looked potentially engineered, but they needed to investigate further. Glenn writes they concluded COVID came from a lab. A lie. He thinks you’re stupid.

Glenn Greenwald

@ggreenwald

3 years

One of the most bizarre and still-unexplained episodes in the COVID pandemic was the group of scientists who told Fauci in late January they concluded COVID came from a lab. Within days, they publicly recanted, then received millions in grants from NIAID, controlled by Fauci.

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Stephen Goldstein

@stgoldst

4 years

@aetiology @LACaldwellDC @SpeakerPelosi @DNC If the Capitol physician signed off that's a real problem. We can argue Pelosi *should* know better regardless, but still.

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Stephen Goldstein

@stgoldst

6 years

@StuPolitics Ah yes, the totally sensible economic argument that the richest country in the world, which prints money for the world, is too poor to not keep letting non-rich people die for no reason.

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Stephen Goldstein

@stgoldst

3 years

This narrative of Tony Fauci as puppet master pulling the strings of virologists the world over is so stupid it's hard to believe the journalists pushing it actually believe it.

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Stephen Goldstein

@stgoldst

4 years

The key figure from Moderna. 6.4-fold drop in neutralization against the SA variant, but neutralizing titers remain >1:100 for all sera tested (and generally much more). We’re okay because starting titers (2 doses) are >1:1000.

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Stephen Goldstein

@stgoldst

4 years

If you're spending time undermining a single-dose, fridge-stable, highly tolerable COVID-19 vaccine...even if it's in good faith you need to think really hard about whether you're making a positive impact or possibly getting people killed.

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Stephen Goldstein

@stgoldst

3 years

Antibody vs T-cell framing drives me crazy given the role of the latter in generating the former.

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Stephen Goldstein

@stgoldst

3 years

I would really urge fellow virologists not to speak with anyone from the @washingtonpost at this point given the anti-scientific disinformation campaign led by one of its most prominent voices.

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Stephen Goldstein

@stgoldst

4 years

If AstraZeneca agrees to market an insufficiently tested vaccine they should be permanently barred from the US market by the next administration.

Steve Herman

@W7VOA

4 years

The @realDonaldTrump administration is considering bypassing normal US regulatory standards to fast-track an experimental #coronavirus vaccine from the #UK for use in America ahead of #Election2020 , reports @FT .

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Stephen Goldstein

@stgoldst

3 years

ICYMI Dr ⁦ @angie_rasmussen ⁩ and I wrote about why the best evidence we have still points to a natural origin of #SARSCoV2 .

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Stephen Goldstein

@stgoldst

3 years

An Ebola virus strain from Asia first "emerged" in the Washington DC suburbs near a military BSL4 lab that actually *did* previously do offensive bioweapons research. It...didn't come from the lab.

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Stephen Goldstein

@stgoldst

4 years

faster than might happen through a normal course of co-evolution with a new host. I'll close by saying I could be totally wrong and maybe #SARSCoV2 has nothing in common with the endemic CoVs. But I think we throw out existing knowledge at our peril.

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Stephen Goldstein

@stgoldst

5 years

@mattyglesias N95 respirator masks are genuinely ineffective without proper fit testing and training. Health care workers are trained, everyone else isn’t. Regular surgical masks are good for sick people to wear, not useful for protecting healthy people.

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Stephen Goldstein

@stgoldst

3 years

Given the clear signals of convergent evolution of #SARSCoV2 it should be blindingly obvious that this virus did not emerge “pre-adapted” to humans. It emerged good enough.

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Stephen Goldstein

@stgoldst

3 years

The latest FOIA dump from @theintercept on EcoHealth Alliance-WIV funding is extremely strong evidence the WIV was only working on SARS1-like viruses. Not a hint of experimental work on viruses related to to #SARSCoV2 . Goes strongly against the plausibility of a lab release.

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Stephen Goldstein

@stgoldst

4 years

The virus will continue to mutate, and multiple exposures are better than 1 or 2 anyway. The good news is vaccine-induced immunity looks better than immunity from natural infection. Science is amazing! We are going to see flare-ups of #SARSCoV2 over time as immunity

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Stephen Goldstein

@stgoldst

6 years

@sethmoulton The silent majority that wants a push led by white men to unseat the first female Speaker, and most effective legislator of our lifetime? You think that’s what the base of the Democratic Party wants?

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Stephen Goldstein

@stgoldst

2 years

@mtracey So you’re suggesting a powerful Jewish-American might have dual loyalty?

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Stephen Goldstein

@stgoldst

4 years

survivors would be horrific. So we *have* to use the 21st century tools at our disposal to accelerate the time-frame for pushing #SARSCoV2 into this kind of mostly harmless ecological niche. We have to vaccinate - as close to everyone as possible. And we'll need boosters.

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Stephen Goldstein

@stgoldst

4 years

The pace of science during this pandemic is amazing. Decades of investment in basic research paying off huge.

Moderna

@moderna_tx

4 years

We just announced that the first participants have been dosed with our modified COVID-19 vaccines, designed to address the potential need for booster vaccine candidates, in an amendment to the ongoing Phase 2 clinical study. Read more:

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Stephen Goldstein

@stgoldst

3 years

A coronavirus pandemic was essentially predicted. So it happened. If it was mundanely foreseeable there’s no reason to reach for outlandish scenarios as to how it started.

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Stephen Goldstein

@stgoldst

3 years

The state of the evidence on the origin of SARS-CoV-2, new critical review featuring myself @arambaut @angie_rasmussen and many more

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Stephen Goldstein

@stgoldst

7 years

Why's it obvious? He's one of the President's biggest supporters.

Deena Zaru Pettiford 👩🏻‍💻

@Deena_Zaru

7 years

Ryan on Trump tweets: "Obviously I don't see that as an appropriate comment," doesn't improve the tone of the debate

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Stephen Goldstein

@stgoldst

3 years

The amazing thing to me about the lab leak hypothesis isn't that people find it plausible - shit happens. It's that none of the *journalists* pushing it the last week or two seem to care whether there's any evidentiary support for it.

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Stephen Goldstein

@stgoldst

4 years

wanes among some populations, new variants arise, or when the virus hits communities with low vaccine uptake. That means there will be local or regional needs for public health measures to come back temporarily. We *have* to be prepared to do this.

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Stephen Goldstein

@stgoldst

5 years

@nktpnd I’ll happily stake my PhD studying coronaviruses on this not being any kind of engineered virus.

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Stephen Goldstein

@stgoldst

4 years

Notably despite relatively encouraging results, they’re all doing exactly what @trvrb recommended - testing a booster based on the SA variant immediately and developing a protocol for it.

Moderna

@moderna_tx

4 years

We just announced that the Moderna COVID-19 Vaccine retains neutralizing activity against emerging variants first identified in the U.K. and the Republic of South Africa. Read more:

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Stephen Goldstein

@stgoldst

3 years

We still don't know anything - literally nothing, about the intrinsic virulence of #omicron

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Stephen Goldstein

@stgoldst

4 years

@Olivianuzzi Do you place any limits on this? Calling for genocide okay as long as you run a counter-argument?

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Stephen Goldstein

@stgoldst

4 years

MERS-CoV can infect lung microvascular endothelial cells in culture. Mouse hepatitis virus (prototypical CoV), loves liver endothelial cells, like really loves them. Few things new under the virology sun. It's a bad virus, we don't have to make it sound extra weird though.

Eric Feigl-Ding

@DrEricDing

4 years

🤔 Is coronavirus a VASCULAR disease too? New Lancet study suggests #COVID19 might also be vascular disease - with #SARSCoV2 virus now invading endothelial cells causing inflammatory cell death. We are not in a Kansas normal respiratory disease anymore. (Hat tip to @DrZoeHyde )

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Stephen Goldstein

@stgoldst

3 years

It's just incredible to me that @washingtonpost continues to have @joshrogin leading a disinformation campaign about #SARSCoV2 origins and as a leading journalism entity shows no interest in other major theories regarding the virus origins. Just a massive failure of curiosity.

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Stephen Goldstein

@stgoldst

4 years

@StevenSalzberg1 This is insane. You can’t say it’s safe on a large scale based off of 45 people. And we unequivocally do not have the data to show they work. You’re just bolstering the idea there’s some conspiracy to hold back vaccines. Outrageously irresponsible.

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Stephen Goldstein

@stgoldst

4 years

Brief commentary on Robert Redfield not knowing what he's talking about. First, one recent paper suggests there *were* adaptive changes during early transmission in humans

A selective sweep in the Spike gene has driven SARS-CoV-2 human adaptation

While SARS-CoV-2 likely has animal origins1, the viral genetic changes necessary to adapt this animal-derived ancestral virus to humans are largely unknown, mostly due to low levels of sequence...

www.biorxiv.org

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Stephen Goldstein

@stgoldst

2 years

Interesting - first report of a MERS-related virus in pangolins. Closely related to bat virus HKU4 which can infect human cells. Hopefully published soon.

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Stephen Goldstein

@stgoldst

4 years

Credible case reports of #SARSCoV2 reinfections have started to emerge, in contrast to earlier reports that were certainly just persistent PCR+s. It's important to document these and studying such cases in large numbers will inform our understanding of SARS2 immunity. However

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Stephen Goldstein

@stgoldst

3 years

Missed this for a long time - SARS-CoV(1) was found in farmed civets outside Wuhan back in 2005, far extending its geographic range known from the 2002-2003 human epidemic.

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Stephen Goldstein

@stgoldst

4 years

It’s clearly not right to say there are no side effects. None were severe enough to outweigh what seems to be considerable benefit. But people need to be properly educated on what side effects to expect or we’re going to have a real problem.

Andrea Mitchell

@mitchellreports

4 years

On how he's doing after the Pfizer trial, @WalterIsaacson : "No side effects at all. And clearly they've had 44,000 people go through this trial, half of them getting the real vaccine. There's been no side effects. There's no danger in these vaccines" #AMRstaff

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Stephen Goldstein

@stgoldst

2 years

@mtracey I wonder. Anyways, time for some more Holocaust tweets?

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Stephen Goldstein

@stgoldst

4 years

And the other good news is that even if we don't have vaccines for really little kids soon, the odds are so heavily in their favor with this virus. With aggressive vaccination and public health we can eliminate most of the mortality and morbidity caused by this virus *much*

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Stephen Goldstein

@stgoldst

4 years

Adding - big reason I am confident in resilience of vaccine efficacy in the face of new variants is super high neutralizing antibodies after two doses. They are *very* low after 1. This is courting disaster.

Stephen Goldstein

@stgoldst

4 years

Much more than a week ago we have substantial scientific data to support the absolute necessity of a second dose. This is simply public health policy unsupported by available data. There’s no magic wand to make things true about the vaccines that aren’t.

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Stephen Goldstein

@stgoldst

3 years

The folks @medpagetoday asked what I thought of Robert Redfield's recent comments to CNN on #SARSCoV2 ...and I didn't think much of them. I try to explain why here

Op-Ed: Why Redfield Is Wrong on SARS-CoV-2 Origins

Scientific data simply don't support the former CDC director's claims

www.medpagetoday.com

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Stephen Goldstein

@stgoldst

4 years

@CT_Bergstrom I like this thread overall, but I think the first sentence is not strong enough. It is definitively not an engineered bioweapon, and I say that as a scientist who by nature and training avoids being definitive.

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Stephen Goldstein

@stgoldst

5 years

@ZekeJMiller That’s actually an optimistic view, believe it or not

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Stephen Goldstein

@stgoldst

3 years

Very interesting that an expert group of virologists carefully considered the possibility #SARSCoV2 was engineered...and decided it wasn’t.

Jimmy Tobias

@JamesCTobias

3 years

Very interesting email from the Fauci documents obtained by @JasonLeopold :

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Stephen Goldstein

@stgoldst

4 years

I think there's understandably a sense that SARS-CoV-2 must have emerged via an unusual scenario to be able to cause such mayhem in humans and this is coloring a lot of analysis. Stark reality is that probably nothing special happened to this virus recently, except we ran into it

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Stephen Goldstein

@stgoldst

4 years

The important thing to remember folks, is that viruses evolve quickly but hundreds of millions of years of evolution has produced a hell of an immune system.

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Stephen Goldstein

@stgoldst

5 years

Viruses acquire mutations every single time their genome is copied. Treat this with *extreme* caution. Almost all mutations are meaningless.

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Stephen Goldstein

@stgoldst

3 years

Glenn Greenwald has the thinnest possible understanding of these issues, topped off with a brazen lie that proposing a lab leak was censored. The most vocal lab leak proponent got a book deal with a major publisher - the opposite of censorship. Greenwald thinks you’re suckers.

Glenn Greenwald

@ggreenwald

3 years

To Deny the "Lab Leak" COVID Theory, the NYT and WPost Use Dubious and Conflicted Sources -- all without disclosing any of this

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Stephen Goldstein

@stgoldst

3 years

@GuptaR_lab Nice data but one thing. TMPRSS2 is not a receptor - it cleaves at S2’. With less furin cleavage at S1/S2 as you found it makes sense omicron is more dependent on endosomal pathway. Very similar to mouse hepatitis virus strains that have different S1/S2 sites.

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Stephen Goldstein

@stgoldst

6 years

@BresPolitico Is yelling at the President a crime? Did they question Joe Wilson?

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Stephen Goldstein

@stgoldst

3 years

The idea that after 6 months people are immunologically naive is simply wrong. Nothing is absolute but the data clearly shows memory cells persist and even expand past 6 months. And variants don’t (so far) impact cellular immunity.

Gupta Lab

@GuptaR_lab

3 years

@SunnyL723 @dgurdasani1 That is plainly wrong - people die on re infection with variants different to the original infecting virus. Immunity from natural infection decays within 6 months and often earlier

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Stephen Goldstein

@stgoldst

4 years

there's a huge catch. The period of time it took from emergence to mostly harmless for those other viruses may have been years, it could have been a decade! We can't afford that kind of time-span, the death toll, economic toll, and toll on the health of

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Stephen Goldstein

@stgoldst

3 years

The #SARSCoV2 pandemic began at the Huanan Seafood Market

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Stephen Goldstein

@stgoldst

3 years

Neutralization data for #omicron is coming in fast now, and it doesn't all agree. Some is as expected, some is better than expected. I don't know which is right, neither does anyone else. So I'd advise measured reactions, boosters, and waiting for real world epi data.

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Stephen Goldstein

@stgoldst

3 years

I’m not aware of any evidence that people infected with omicron are not contagious at symptom onset. We need to tread *very* carefully with this kind of stuff.

Michael Mina

@michaelmina_lab

3 years

We can use this “new” relationship between symptom onset and infectiousness to our advantage! It’s a feature, not a bug. Now that the world has pre-existing immunity, we have to adjust our thinking. Newly Symptomatic and Ag neg? Probably not infectious now… test again tmrw 3/

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Stephen Goldstein

@stgoldst

2 years

Incredibly honored to be able to contribute to this, now peer-reviewed, study on the emergence of SARS-CoV-2 in Wuhan

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Stephen Goldstein

@stgoldst

4 years

Very exciting to see a big push to squander the US vaccine rollout by loading people up with transient low potency antibodies

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Stephen Goldstein

@stgoldst

2 years

@mtracey I think the day when you’re tweeting out Hitlers justifications for killing the Jews as earnest is a good time to take a couple days to cool off and make sure this is a hill worth dying on. If it is, fair enough and that’s informative. But worth making sure.

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Stephen Goldstein

@stgoldst

4 years

There are currently 4 endemic human CoVs: OC43, 229E, NL63, HKU1. OC43 and HKU1 are sort of closely related, same for 229E and NL63. Overall, pretty divergent though. More different than SARS1 and SARS2, for example. They all came from animals, and they all cause mostly

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Stephen Goldstein

@stgoldst

4 years

My take is obviously experts have been wrong about some things, but viewing this as a failure is a fundamental misunderstanding. If you want scientists to know everything important about a new virus you’ll need to wait years. That isn’t really an option here...

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Stephen Goldstein

@stgoldst

3 years

Yes, this was so secretive all the information is available in Table 1 since August 2020

David Fisman

@DFisman

3 years

Remember kids, and...um...regimes: the internet is forever.

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Stephen Goldstein

@stgoldst

4 years

because we start building up immunity as kids and keep doing it with repeated exposure as young adults. So, will #SARSCoV2 end up as "just another endemic CoV"? The truth is, I don't know, but I *think* probably yes - BUT

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Stephen Goldstein

@stgoldst

2 years

@mtracey Well I thought the ones you deleted were illuminating, so maybe it’s time for you to expound?

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Stephen Goldstein

@stgoldst

4 years

What if we just didn’t farm mink?

NYT Health

@NYTHealth

4 years

Vaccines for mink could benefit the health of humans, as outbreaks on fur farms pose a public danger

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Stephen Goldstein

@stgoldst

4 years

This is so stupid. Without collaborating we wouldn’t even know about this huge pool of SARS-like viruses in bats. We’d have no idea where the pandemic came from. We’d be that much farther behind the game. A shame science is being subjugated to hawkishness in these pages

Washington Post Opinions

@PostOpinions

4 years

The coronavirus crisis shows the risks of scientific collaboration with China, @JoshRogin writes

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Stephen Goldstein

@stgoldst

3 years

There’s nothing to consider. The bans should be lifted immediately.

Josh Wingrove

@josh_wingrove

3 years

Biden said that he's considering lifting the travel restrictions on people who've recently been in any one of eight southern African nations. The measures were imposed to slow the spread of omicron, which is now the dominant strain in the U.S.

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Stephen Goldstein

@stgoldst

4 years

pretty similar, mild disease. We're basically all infected in childhood, more than once. This is probably important.

First infection by all four non-severe acute respiratory syndrome human coronaviruses takes place...

Background Non-severe acute respiratory syndrome (non-SARS)-related human coronaviruses (HCoVs), including HCoV-229E, -HKU1, -NL63, and -OC43, have been detected in respiratory tract samples from...

bmcinfectdis.biomedcentral.com

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Stephen Goldstein

@stgoldst

3 years

This is a massive underestimate of asymptomatic infections. It’s likely that the large majority of breakthrough infections are asymptomatic, do not transmit, and are essentially irrelevant from a medical and public health standpoint.

Chise

@sailorrooscout

3 years

Latest data on breakthrough infections out of the CDC: 123,000,000+ fully vaccinated 354 asymptomatic infections (0.0002%) 1,368 COVID-related hospitalizations (0.0011%) 290 COVID-related deaths (0.0002%) The vaccines work extremely well so do get vaccinated when you can.

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Stephen Goldstein

@stgoldst

4 years

Now, the point here isn't that #SARSCoV2 isn't serious. It's devastating! The point is that a lot of CoVs can be devastating in older and vulnerable populations. When it comes to #SARSCoV2 thats literally hundreds of millions people worldwide. With the other CoVs, it's not

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Stephen Goldstein

@stgoldst

4 years

@Olivianuzzi Not to mention, the Times let this stand alone.

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Stephen Goldstein

@stgoldst

4 years

Finally, from a "biological standpoint" as he says, there's no reason to think serial passage in culture produces a virus more transmissible in humans. My conclusion - Redfield (who declares I'M A VIROLOGIST) is in fact a terrible virologist.

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Stephen Goldstein

@stgoldst

2 years

@mtracey Oh I read all the tweets, but you’re right, I should circle back to your long-form revisionism. Happy to make that time investment to learn who was really, at root, responsible for murdering my relatives.

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Stephen Goldstein

@stgoldst

4 years

Yep. I expect very similar results for the Moderna vaccine at least.

Florian Krammer

@florian_krammer

4 years

The reason why I am so enthusiastic about this is that this is likely also great news for the other vaccine candidates.

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Stephen Goldstein

@stgoldst

3 years

Supposed Chinese obfuscation about the Wuhan Institute of Virology has often been taken as evidence of a lab leak. But here’s some real shadiness and opacity about what animals were for sale at the Huanan market. This must be a follow-up priority

Covid investigators must interview Wuhan stall owners, says virologist

Efforts to find origin of coronavirus ‘must look at what animals were in the market in late 2019’

www.theguardian.com

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Stephen Goldstein

@stgoldst

4 years

SARS1 and MERS are notorious for hitting older and sicker folks harder than anyone else. Their age-gradent is severe. They have this in common with #SARSCoV2 , but of course many more cases of the latter means more disease for everyone

Prognostic Factors for Severe Acute Respiratory Syndrome: A Clinical Analysis of 165 Cases

Abstract. This study analyzes single factors that affect the prognosis of severe acute respiratory syndrome (SARS) and establishes a prognosis model by mul

academic.oup.com

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Stephen Goldstein

@stgoldst

4 years

These viruses infect us as kids and it's pretty harmless. #SARSCoV2 , we all know by now is usually pretty mild in kids. What about the really dangerous CoVs SARS1 and MERS?

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Stephen Goldstein

@stgoldst

4 years

And here we go, the lie propagates. One guy with a position at Hopkins throws it out there and it goes mainstream. We DO NOT know yet if vaccines that have proved safe in 45 healthy people are safe and effective.

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Stephen Goldstein

@stgoldst

3 years

One of these days someone who knows what they’re talking about is gonna write a book about #covid

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Stephen Goldstein

@stgoldst

4 years

as kids (see above) and basically all have antibodies to them. There are essentially no "immunologically naive" adults infected with endemic CoVs.

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Stephen Goldstein

@stgoldst

2 years

This is an absolute blockbuster from @sciencecohen

Where did the pandemic start? Anywhere but here, argue papers by Chinese scientists echoing party...

China doesn’t just reject the “lab-leak” theory. It now claims SARS-CoV-2 came from another country

www.science.org

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Stephen Goldstein

@stgoldst

4 years

So can we get any insight at all into how the endemic viruses behave in the same types of populations that are so susceptible to #SARSCoV2 ? It's hard - but we're not totally clueless. An outbreak of OC43 in a nursing home where 8/95 infected residents died

An Outbreak of Human Coronavirus OC43 Infection and Serological Cross-reactivity with SARS Corona...

In summer 2003, a respiratory outbreak was investigated in British Columbia, during which nucleic acid tests and serology unexpectedly indicated reactivity for severe acute respiratory syndrome...

www.ncbi.nlm.nih.gov

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Stephen Goldstein

@stgoldst

4 years

One thing striking to me about much of the #SARSCoV2 #COVID19 discussion is how little leading CoV experts feature in it. The younger PIs are on twitter but too busy. The older PIs with 100s of years collective experience are inactive on twitter and largely absent from media.

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Stephen Goldstein

@stgoldst

3 years

This entire article is ridiculous

Liz Szabo

@LizSzabo

3 years

Researchers have established that SARS-CoV-2, which is responsible for the disease known as covid-19, can infect patients who are also afflicted by other coronaviruses, possibly leading to an exchange in genetic material.

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Stephen Goldstein

@stgoldst

5 years

@Max_Fisher And the North Vietnamese irregulars did just fine against us anyway

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Stephen Goldstein

@stgoldst

3 years

@andyaschmidt @acritschristoph @macroliter @MichaelWorobey @angie_rasmussen @arambaut @K_G_Andersen @robertson_lab @MarionKoopmans Two lineages were present at the market we now know. This makes an actual market origin virtually certain.

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Stephen Goldstein

@stgoldst

4 years

It can be done

Eric Topol

@EricTopol

4 years

In the battle vs B.1.1.7, Ireland and the UK are winning. That takes a lot of work and we should all learn from them.

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Stephen Goldstein

@stgoldst

4 years

Suggesting hurt feelings are worse than 90,000 dead just in this country has to be one of the most odious tales of the pandemic.

Vinay Prasad MD MPH

@VPrasadMDMPH

4 years

@CT_Bergstrom @jflier @stephaniemlee Our issue is that if academic disagreement gets so personal and so political, we are doomed. It's worse than Covid. Stanford authors deserve to have their study gutted, but not the personal attacks. That is a slippery slope even if they go on bad TV shows.

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Stephen Goldstein

@stgoldst

3 years

Plenty of serious names on this letter. While I strongly believe a "natural" zoonotic event is the most likely origin of the pandemic, the arguments put forward here are well-considered and well-justified. Further investigation is warranted.

Bloom Lab

@jbloom_lab

3 years

In letter published in @ScienceMagazine today, I join 17 other scientists in calling for further investigation of #SARSCoV2 origins, including objective consideration of both accidental lab leak and natural zoonosis: (1/n)

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Stephen Goldstein

@stgoldst

3 years

I’m aware of no experiment ever conducted (let alone often!!!) to make a coronavirus more deadly to humans. Please, @washingtonpost consider correcting this. This makes virologists look psychotic.

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Stephen Goldstein

@stgoldst

4 years

@StevenSalzberg1 This is really infuriating. You have a position at Hopkins and lots of credibility and you’re just spouting absolute dishonesty about the status of vaccine development. It’s unconscionable.

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Stephen Goldstein

@stgoldst

3 years

The idea that the initial vaccine course didn’t produce immune memory is actually a nasty little tidbit of misinformation. Boosters are about circulating antibody levels, no evidence of issues with memory.

CNBC's Closing Bell

@CNBCClosingBell

3 years

"The first two doses were provided so close together that they probably really served as two primes...This third dose is probably going to serve as a true booster in terms of inducing immune memory and...a more durable response," says @ScottGottliebMD on Covid-19 booster shots.

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Stephen Goldstein

@stgoldst

4 years

So if #SARSCoV2 has this in common with SARS1 and MERS, does that distinguish it significantly from the endemic viruses, those mostly harmless ones? It's hard to say since SARS1, #SARSCoV2 , and MERS infect people as adults for the first time. We *all* get the endemic viruses

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Stephen Goldstein

@stgoldst

3 years

@BallouxFrancois I agree it's exploitative but calling it equivalent to antivax propaganda, which deliberately attempts to get people killed, is really very wrong in my view. Minimizes to malice of the antivax movement.

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Stephen Goldstein

@stgoldst

4 years

Well, i guess a Nobel prize isn't protective against nonsensical COVID19 takes.

Michael Levitt

@MLevitt_NP2013

4 years

US COVID19 will be done in 4 weeks with a total reported death below 170,000. How will we know it is over? Like for Europe, when all cause excess deaths are at normal level for week. Reported COVID19 deaths may continue after 25 Aug. & reported cases will, but it will be over.

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Stephen Goldstein

@stgoldst

4 years

Or an outbreak of NL63 in a long-term care setting where 3/20 patients died. The risk-factors: heart disease, dementia, hypertension, diabetes, and lung disease. Same risk factors as #SARSCoV2

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