Vladimir Shakirov @schw90 Twitter profile

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Vladimir Shakirov

@schw90

10 months

Sign this open letter to the European Parliament by stating your support explicitly in replies to this tweet.

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Vladimir Shakirov

@schw90

11 months

@elonmusk Right now, a billion people suffer from diseases and disabilities of old age. We don't need to discuss cosmological immortality. We need to end this suffering. We need a Moonshot project to defeat cancer, cvd, dementia, and aging itself. Stay healthy and live as long as you wish

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Vladimir Shakirov

@schw90

1 year

1/7 is a brilliant project with an excellent Whitepaper: I suggest adding a crucial statement to the Whitepaper: first, we need to secure a decisive support of NIH researchers (~300k people) for the #MoonshotProjectToEndAging .

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Vladimir Shakirov

@schw90

11 months

Open letter to the US Congress: launch the Moonshot Project to grant people choice to stay healthy and alive, including in their elder years and beyond, for as long as they desire. Dear Members of Congress, and Mr President,

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Vladimir Shakirov

@schw90

10 months

Sign this open letter to the US Congress by stating your support explicitly in replies to this tweet.

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Vladimir Shakirov

@schw90

10 months

@BrentNally @elonmusk I like how Elon agreed in this interview that death would be a choice in a positive AI scenario (go to 19:23 to see).

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Vladimir Shakirov

@schw90

10 months

Sign this open letter to the US Congress by stating your support explicitly in replies to this tweet.

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Vladimir Shakirov

@schw90

11 months

@GabrielMariya @CNIOStopCancer @EUScienceInnov We need a Moonshot Project to end aging and age-related diseases. Aging kills 1 million people every week. Aging is about suffering, disabilities, diseases. At the same time, aging research is severely underfunded. We need a Moonshot with $20bn/year going to $100bn/year in 2030.

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Vladimir Shakirov

@schw90

1 year

Moonshot project to end aging - this shall be our main motto. Convincing scientists (and other people) to make statements in support of the launch of the Moonshot Project - this shall be our main competition. We need a group of people to get this started.

Nathan S. Cheng thinks you should work on aging.

@realNathanCheng

1 year

If we saw it fit to declare war on cancer, surely we should also declare war on aging?

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Vladimir Shakirov

@schw90

11 months

Open letter to the US Congress: launch the Moonshot Project in medical science to eliminate suffering caused by disabilities, diseases and conditions of old age, with the ultimate goal of guaranteeing individuals' right to health and life for as long as they desire.

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Vladimir Shakirov

@schw90

10 months

@bryan_johnson What is the difference? If you don't die, you live forever. If you don't live forever, it means you die at some point.

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Vladimir Shakirov

@schw90

10 months

@sama No, we need to stop AGI research until we have a solid clear theory or at least consensus that AGI research wouldn't lead to human extinction or other global catastrophe. And hopefully it will be regulated that way.

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Vladimir Shakirov

@schw90

11 months

Probably people would understand the concept of *delay* aging (and onset of age-related diseases such as cancer, heart diseases, dementia etc.). It's what people think they see sometimes in other people. Like, let 70 be new 40, 90 new 60. And it's the first step to defeat aging.

Agingdoc⭐David Barzilai🔔MD PhD MS MBA DipABLM🩺

@agingdoc1

1 year

@jpsenescence Perception: you can sometimes cure cancer, but can't cure aging. To most people it sounds like you're working on a time machine. So it's more than a simple PR problem. It's fundamental aging biology education. The 1st real gerotherapeutic will catalyze these dialogues at scale.

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Vladimir Shakirov

@schw90

11 months

It seems like @statto is also very enthusiastic: "We could be just $100bn away from curing aging" Good thing to try!

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Vladimir Shakirov

@schw90

11 months

Here is my proposed outline for allocating $4 billion per year to the Moonshot for aging research: Same for $20bn/year:

$20bn/year research plan outline

RESEARCH PLAN $20B/YEAR: GRANTS DISTRIBUTION (TOTAL 30k grants = $20 billion / year) Here, 1 grant is taken equal to $400k/year direct costs and $267k/year indirect costs. BRIEF ENGINEERING APPROAC...

docs.google.com

Aubrey de Grey

@aubreydegrey

11 months

@schw90 @MikhailBatin @greg_fahy @kaimicahmills @mkaeberlein @TheA4li @USTranshumanist @felixwerth2 @mehrForschung @statto @KarlPfleger @zach @ILAISRLA @BrentNally I had an in-depth conversation about this with Misha Batin yesterday and we have a plan - please check in with him and let's get it done!

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Vladimir Shakirov

@schw90

10 months

@ArthurB Don't regulate nuclear bombs you doomers! They can be used for good: to deflect asteroids, to mine Earth for resources, to clear path in mountains. It's just a tool. It's not A-bomb that kills you but person who explodes it! It's safest when everyone has A-bomb, because of MAD.

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Vladimir Shakirov

@schw90

11 months

Join our Twitter chat on defeating aging. DM me or leave a comment and I add you.

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Vladimir Shakirov

@schw90

11 months

Sadly, it seems like US Transhumanist Party potential candidates for 2024 elections Tom Ross and Daniel Twedt are not really interested in life extension topic too much. Daniel Twedt: (3min) Tom Ross: (2min, with even worse answer)

U.S. Transhumanist Party Presidential Candidate Roundtable – Tom Ross...

On Sunday, May 7, 2023, the U.S. Transhumanist Party presented its Presidential Candidate Roundtable, featuring Tom Ross and Daniel Twedt, who are seeking th...

www.youtube.com

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Vladimir Shakirov

@schw90

10 months

We should write open letter to Aubrey de Grey and other top people in our field that they should get together, approve the wording of the open letter calling for $20bn/year Moonshot on aging research, and publish it on their resources (or just $4bn/year? let them decide).

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Vladimir Shakirov

@schw90

11 months

@PeterDiamandis "This century" means many of us wouldn't survive. We should demand launch of Moonshot project to end aging and diseases. In that case less people would experience a brutal violation of their right to life and health by so-called "natural" aging and death.

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Vladimir Shakirov

@schw90

11 months

Can we make an Open Letter of scientists calling for a #geroscience Moonshot? Just imagine if it's not just your personal @mkaeberlein call, but 100+ scientists signed and made support statements. And I think we can convince very much more than just 100 scientists to support it.

Matt Kaeberlein

@mkaeberlein

3 years

The economic case for targeting aging: Proposed @POTUS ARPA-H budget: $6.5 BILLION Economic value of a conservative #geroscience intervention per @davidasinclair @ProfAndrewScott : >$38 TRILLION ROI for a #geroscience moonshot: At least 5846-fold

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Vladimir Shakirov

@schw90

10 months

@aubreydegrey I applaud this Declaration, but we need another Declaration, calling for $20bn/year Moonshot on aging research. Please anyone who reads this: convince Aubrey de Grey or to publish declaration that actually calls for $billions/year on aging research.

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Vladimir Shakirov

@schw90

10 months

@mealreplacer @ESYudkowsky Don't fear tigers, they are just things made of cells, which are composed of molecules. Why are you scared of some bunch of cells? You yourself are the bunch of cells, think of it!

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Vladimir Shakirov

@schw90

1 year

There is now a page on #MoonshotProjectToEndAging in wikipedia on aging:

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Vladimir Shakirov

@schw90

10 months

@aubreydegrey You are the champion of the field. If you publish Open Letter calling for a $20bn/year Moonshot, a lot of aging researchers would sign it. If I publish it, the effect would be much much smaller. Alternatively, or A4LI might publish these Open Letters.

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Vladimir Shakirov

@schw90

11 months

New positive video on cryonics has already 1.9 mln views. I like that @tomscott who has 6.1 mln subscribers on Youtube is with us! Quote from the video: "I think death is a bad thing, and that humanity should be trying to defeat it, the same way we've defeated smallpox".

Adam Gries

@adamgries

1 year

Great feature of @tomorrowbio & @emilkendziorra ! @tomscott "I will say that death is a bad thing and that humanity should be trying to defeat it the same way we've defeated smallpox, but that is a controversial opinion" Less controversial every day.

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Vladimir Shakirov

@schw90

11 months

To briefly tl;dr the mentioned Open Letters: The first calls for 1% of US GDP for research on how we can stay healthy and alive for as long as we want.

Vladimir Shakirov

@schw90

11 months

Open letter to the US Congress: launch the Moonshot Project in medical science to eliminate suffering caused by disabilities, diseases and conditions of old age, with the ultimate goal of guaranteeing individuals' right to health and life for as long as they desire.

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Vladimir Shakirov

@schw90

1 year

I think we can easily find 200 immortalists here in Twitter. I think it's a good idea to make a list of such people, probably with some tags (for their interests). Maybe there are already such lists or chats.

Mikhail Batin

@MikhailBatin

1 year

@schw90 I think it's early. First we need to include 200 like-minded people in our network. But I don't answer you

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Vladimir Shakirov

@schw90

10 months

Good news everyone! =)

Thomas H. Chapin IV

@tomchapin

10 months

Very interesting to hear @elonmusk talk about the ideal future with AI, universal basic (or high) income, and the concept of death as a choice. Sounds like he finally gets it!

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Vladimir Shakirov

@schw90

10 months

Sign this open letter to the European Parliament by stating your support explicitly in replies to this tweet.

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Vladimir Shakirov

@schw90

11 months

Probably better make Twitter chat. There are much more people in Twitter now than in Discord. That would be more convenient.

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Vladimir Shakirov

@schw90

11 months

Now, let's also discuss open letter on cryonics. Open letter to the US Congress: launch the Moonshot Project on Research and Development of Reversible Cryopreservation

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Vladimir Shakirov

@schw90

11 months

@MikhailBatin The simplest way to join SayForever network is to pin one of our lists and retweet/like/comment the posts which you like. Always remember that we have a chat where you can discuss promotion of indefinite life extension research with us.

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Vladimir Shakirov

@schw90

9 months

@kaimicahmills I like that he is 56 years old, has ~$9.7bn and really wants to defeat death. That means if he succeeds, I will likely succeed too. And he has some chances, especially if he tries hard! I'm however not sure he really tries hard enough.

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Vladimir Shakirov

@schw90

11 months

Let's make a brainstorm. Where from we can take $100bn/year or $220bn/year to fund Moonshot project to end aging? We discuss it also in discord of US Transhumanist Party:

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Vladimir Shakirov

@schw90

1 year

@MikhailBatin @PeterDiamandis I know how to achieve this: we need first to concentrate on getting explicit vocal support from scientific community. When we have say 1000 explicit support statements from NIH scientists, the idea becomes credible while now it's unclear for people whether it is credible.

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Vladimir Shakirov

@schw90

11 months

Andrej Karpathy works at OpenAI, has 780k subscribers, and he is interested in aging research, see also this tweet

Andrej Karpathy

@karpathy

4 years

Aging has 100% mortality rate and no one cares

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Vladimir Shakirov

@schw90

11 months

@AdamSinger I believe we need a Moonshot project on aging research, and that we need an Open Letter of scientists calling US Congress to launch that project. Please DM me on that matter if you also find this important. My draft of open letters is pinned on my page. @AdamSinger

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Vladimir Shakirov

@schw90

10 months

@SF_Longevity @bryan_johnson I think we should write Open Letters of scientists (and other people) calling for a $20bn/year Moonshot Project on aging research. One letter for US Congress, another for European Parliament. Everybody who wants to cooperate on that please write me direct messages.

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Vladimir Shakirov

@schw90

11 months

@EvasTeslaSPlaid I certainly want to live at least a couple of thousand years, healthy and without dementia) Maybe billions, who knows! Forever? I think it's too early to think about that possibility =)

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Vladimir Shakirov

@schw90

9 months

@aubreydegrey What if someone is 115 years old at 2036? Even with Methuselarity, that person would continue to suffer from aging and most likely die in a few years. So when you say about LEV or Methuselarity, what is the cut-off by age that you mean? 115 doesn't fit, what about 90? 80? 70?

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Vladimir Shakirov

@schw90

11 months

I like that @balajis promotes indefinite life extension on Twitter. He has 940k followers, dozens of million dollars, he is a famous founder of idea of network state.

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Vladimir Shakirov

@schw90

10 months

Thousands of experts signed Open letter calling for pause of AGI research A lot of deep learning professionals among them, including the very top people like Yoshua Bengio. AI is developing extremely fast.

Future of Life Institute

@FLI_org

1 year

📢 We're calling on AI labs to temporarily pause training powerful models! Join FLI's call alongside Yoshua Bengio, @stevewoz , @harari_yuval , @elonmusk , @GaryMarcus & over a 1000 others who've signed: A short 🧵on why we're calling for this - (1/8)

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Vladimir Shakirov

@schw90

11 months

@danielsil44 @biogerontology @aubreydegrey @transhumanismAU @TranshumanParty @jpsenescence @ChrisRabane @Martin_Heyam @BrentNally @dw2 @peterxing @LifeExtension @liveforeverclub Can we do it in 2023? I mean, seriously, with open letters to US Congress to fund some kind of a huge Moonshot project to end aging. With support statements from 10k+ scientists.

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Vladimir Shakirov

@schw90

11 months

@BrentNally I wonder if Jeff Bezos can be persuaded to lobby for more funding for aging research in US Congress. He seems to be interested in the topic, and the aging research community seems to have some access to him, as many researchers work at his Altos Labs.

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Vladimir Shakirov

@schw90

1 year

I started to collect information regarding RLE in twitter in my Wikipedia on Aging: People who are reading that and willing to help, do it =)

Mikhail Batin

@MikhailBatin

1 year

@schw90 Just do it

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Vladimir Shakirov

@schw90

11 months

@GlamGrafter We need a huge research project to find a way to cure aging and age-related diseases. Desirably within our lifetime. Aging would be solved, the only question is whether we are the last generation to die of aging or the first that has a choice to live healthy as long as we want.

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Vladimir Shakirov

@schw90

11 months

Research on age-related diseases is crucial. Even if there were no NIA, aging processes would still be (and they are) studied in research on age-related diseases. Currently only 20-30% (~$10b/year) of NIH funding goes to research on age-related diseases:

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Vladimir Shakirov

@schw90

11 months

@MikhailBatin The minimal work most useful for promoting cryonics is to write a new version of Open Letter of scientists on cryonics this time calling for $2bn/year Moonshot on reversible cryopreservation research. My version is here:

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Vladimir Shakirov

@schw90

1 year

My wikipedia on defeating aging: Main topics: 1) Promotion of radical life extension agenda 2) Healthy lifestyle 3) Research

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Vladimir Shakirov

@schw90

11 months

What happened with discord for vitalist supporters? There was once such a discord on and now the link is gone. Can you give an actual link please? @realNathanCheng We the supporters hope there would be a place where we can discuss vitalism.

Nathan S. Cheng thinks you should work on aging.

@realNathanCheng

1 year

Does @elonmusk understand how evil this is? He wants every man, woman, and child on this planet today to die — (mostly involuntarily from diseases of aging)? Including his own children, his parents — everyone? The moral thing to do is give people choice. Fight aging.

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Vladimir Shakirov

@schw90

1 year

@adamgries Please create a space (chat / discord server / slack etc) where those who support ideas can talk to each other.

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Vladimir Shakirov

@schw90

1 year

We can ask scientists (and other people) in Twitter to make a tweet in support of the launch of the Manhattan Project on Aging, with one of our hashtags. And collect all these tweets on some page.

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Vladimir Shakirov

@schw90

11 months

@kaimicahmills What about indefinite healthspan extension? It makes emphasis on health (so no erroneous picture of living 200 years with bad physical and mental health). At the same time, it's about eternity (or so-called "the right to choose when to die", which is strange but people like it).

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Vladimir Shakirov

@schw90

11 months

"Humanity's highest priority should be to fund aging reversal technology" Tomas Pueyo, 300к subscribers. Do you know more people who also support smth like Moonshot Project to end aging? Let's discover them and make a list. DM me who wants to participate.

Tomas Pueyo

@tomaspueyo

2 years

If that's true, you might get the option to live forever. Humanity's highest priority should be to fund aging reversal technology. So YOU must realize this will happen, and it can happen while you're alive if you convince others this is important. RT this!

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Vladimir Shakirov

@schw90

11 months

That's why we need an Open Letter calling for the launch of Moonshot Project to end aging. We need to collect as many support statements of scientists as we can, be it 10k or 100k. That shall make anti-aging Moonshot credible in the eyes of politicians, experts and general public

Matt Kaeberlein

@mkaeberlein

3 years

@jpsenescence @DrMorganLevine @Halsted_19 @johnharris1969 @realNathanCheng Did you know geroscience was on the table for an Obama moonshot? Do you know why it wasn't selected? At least in part because it wasn't considered credible science

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Vladimir Shakirov

@schw90

11 months

@aubreydegrey @LongevityDublin I hope Dublin declaration is smth like Open Letter to US Congress to launch a Moonshot project on aging with funding at least 1% of US GDP. We need to state our desire clearly. Of course, there can be many open letters, including a special Moonshot project on reversible cryonics

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Vladimir Shakirov

@schw90

11 months

@yangranat Increasing healthspan of people who wage healthy lifestyle by another 10 years would lead to increasing their lifespan by much more than 1 year.

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Vladimir Shakirov

@schw90

10 months

"Mitigating the risk of extinction from AI should be a global priority" Signed by: Geoffrey Hinton, Yoshua Bengio, Ray Kurzweil, Bill Gates and hundreds of other researchers and notable figures, including 61 DeepMind and 30 OpenAI researchers.

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Vladimir Shakirov

@schw90

11 months

@tferriss My goal is to help launch a Moonshot Project to end aging. Aging kills more than 100k people every single day. Aging slowly degrades quality of human lifes. We need to solve that asap. Join us, @tferriss . We are about to launch a large Open Letter on this.

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Vladimir Shakirov

@schw90

9 months

@KristerKauppi How much more years or months do you expect an average motivated person with healthy lifestyle would live due to rapamycin interventions?

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Vladimir Shakirov

@schw90

10 months

@EricVerdin We need Open letter of scientists (and other people) calling for a $20bn/year Moonshot on aging research. In that case, we can really hope to make aging optional in 20-30 years. See this Open letter as an example: I have a draft:

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Vladimir Shakirov

@schw90

11 months

@GabrielMariya @CNIOStopCancer @EUScienceInnov Another issue is reversible cryopreservation. It can potentially save millions of lifes but its research is severely underfunded, see open letter of scientists in support of cryonics We need >$1bn/year Moonshot on reversible cryopreservation research asap

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Vladimir Shakirov

@schw90

11 months

Agree! I have a draft of Open Letter calling US Congress to launch a Moonshot Project to end aging with $100bn/year, in my pinned post: I envision future where 10k scientists supported that Open Letter. I think it's feasible within a year if we really try.

vitalik.eth

@VitalikButerin

4 years

@CDNBiohacker I agree! I just think we should be devoting at least a whole percentage point of GDP to working on these things.

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Vladimir Shakirov

@schw90

11 months

@PeterDiamandis I suggest all of you who are people of action, not just "liked and forgot", to DM me directly. We have chat on Open Letters. We'll launch it. It's ridiculous that we don't have 10k support statements of scientists under such Open Letter. Given how many of us want to defeat aging

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Vladimir Shakirov

@schw90

11 months

@MikhailBatin @greg_fahy @kaimicahmills We as a field have a lot of resources to ensure large number of signatures, wide audience coverage, and to achieve that both Europarliament and US Congress actually debate our Open Letters calling for a lot of $billions/year on aging research and cryonics. We can do it quite fast

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Vladimir Shakirov

@schw90

9 months

@ylecun Aside from Terminators, what if we step by step give AI all control over economy, police, military? either due to objective laws of competition (you either do that or lose) or our laziness, or increasing complexity of tech. What if by 2100 our world is de-facto controlled by AI?

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Vladimir Shakirov

@schw90

1 year

Who will be the hardest to convince about the importance of launching a Moonshot anti-aging project?

Scientists, experts

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Congress Members

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People

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Vladimir Shakirov

@schw90

11 months

@NastyaKostylev7 We need universal basic immortality (U.B.I.)

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Vladimir Shakirov

@schw90

9 months

@AlexAlarga In "cure cancer" scenario AI has much more GPUs and help of humankind. In "kill all humans" bad actor most likely has several OOM less compute, and bad AI faces a mighty resistance from good actors with more powerful AIs.

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Vladimir Shakirov

@schw90

10 months

@primalpoly @balajis Maybe we need to publish open letter calling for a Moonshot on AGI safety with like $4bn/year funding? I see aligned AGI as entity that wouldn't interfere in our life at all except giving us some UBI and perfect health for as long as we want + preventing us from accidents/kills.

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Vladimir Shakirov

@schw90

10 months

@adamgries Word "forever" shifts focus from reality to philosophy, prompting thoughts about the heat death of the universe, philosophy and unfalsifiability of living forever. Instead, we should prompt people to think about defeating aging, diseases, and deaths of people they care about.

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Vladimir Shakirov

@schw90

10 months

@senstweet We don't know. We need more funding to try every way and see what will be the best. Maybe it would be regeneration with stem cells, or replacement of body and even gradual replacement of the brain in Jean Hebert style. Maybe reversible cryopreservation. We need a huge Moonshot.

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Vladimir Shakirov

@schw90

10 months

@AISafetyMemes "Father, mother, I want to introduce you my gf, she's so cute. Just put on these Oculus VR glasses, you'll see! We're going to have our virtual child in a year or so. You know, it's hard to raise a child these days, even in VR"

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Vladimir Shakirov

@schw90

10 months

Which header of Open Letter do you prefer? Write a number or several numbers, or suggest your header.

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Vladimir Shakirov

@schw90

11 months

@vadbars Can we make the list of top 10 politicians (elected to anything but the higher the better) who expressed publicly their desire to defeat aging?

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Vladimir Shakirov

@schw90

10 months

@aubreydegrey Can you publish this open letter on the Dublin Longevity Declaration website, as an optional appendix to the Declaration? (as well as 3 other open letters ). Feel free to edit anything, we just need Call to Action for legislative bodies with a specific sum.

Vladimir Shakirov

@schw90

10 months

All four open letters: 1) on aging, to European Parliament: 2) on aging, to US Congress: 3) on cryonics, to European Parliament: 4) on cryonics, to US Congress:

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Vladimir Shakirov

@schw90

11 months

@bryan_johnson What about increasing funding for aging research at least by $1bn/year? though I personally think it deserves much more, even $20bn/year or $100bn/year. A good Moonshot!

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Vladimir Shakirov

@schw90

10 months

@EricVerdin It depends heavily on the amount of funding aging research gets. And aging research field is so young and immature that we don't even have asked governments collectively for a specific large increase in funding.

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Vladimir Shakirov

@schw90

11 months

@SF_Longevity @MikhailBatin @fedichev @turchin @vadbars @tomchapin @madiyar_123 @AlexLarionov @DanilaImmortal @IuriiPotes84621 @InSociEUP @am_adeliya @EndrigoGlauco @CuringAgingConf @SsJankauskas @GriffinBrumley @_sviridov_ @EvanMorgun @VampArtyom Most people want. So I guess I'm just normal and have no major psychological issues, that's why. Oh, and I fully understand the assumptions like being physically and mentally healthy. Also, I can't speak for myself in a million years from now. No one can, we can just guess.

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Vladimir Shakirov

@schw90

1 year

2/7 Collectively, it should be feasible to obtain first 1000 signatures or support statements of NIH scientists within 6 months. This would already mark a great achievement and grant the immortalist movement an unprecedented level of credibility.

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Vladimir Shakirov

@schw90

11 months

It's nice to see people with passion to #MoonshotProjectToEndAging ! We need to unite all Moonshot enthusiasts for a discussion and action.

Bonnie Kavoussi

@bkavoussi

3 years

My latest for @JoinLincoln : The case for a longevity moonshot

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Vladimir Shakirov

@schw90

10 months

@EricVerdin What is the most convincing reason not to believe in possibility of living googolplex years? (just some practical definition of almost immortality)

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Vladimir Shakirov

@schw90

11 months

There is a great petition by @TheA4li calling for funding $1bn/year for Division of Aging Biology of NIA. However, nobody can be impressed by number of anonymous petition signatures. We need them non-anonymous as in Open Letter of scientists on cryonics:

Scientists' Open Letter on Cryonics - Biostasis

The official location of the Scientists’ Open Letter on Cryonics is https://www.biostasis.com/scientists-open-letter-on-cryonics. Please link to this URL to access the most recent and accurate version

www.biostasis.com

The Alliance for Longevity Initiatives (A4LI)

@theA4LI

1 year

That is why we have created a petition, requesting increased appropriations to the National Institute on Aging - Division of Aging Biology. You can sign our petition here:

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Vladimir Shakirov

@schw90

11 months

@Nst_Egorova @elonmusk Yeah, his "solution" for gerontocracy problem is many orders of magnitude worse than the problem itself. It's almost like what if we just kill everybody and there would be no gerontocracy at all.

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Vladimir Shakirov

@schw90

11 months

"Delay aging" seems to be too weak to get Moonshot level funding. For people not familiar with LEV it sounds like one still gets deadly cancer or heart attack but say 20 years later. Does it generate enough value for people to be excited enough?

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Vladimir Shakirov

@schw90

9 months

@aubreydegrey Creating a slack on life extension research and promotion is another very promising idea! so that people communicate more with each other. Especially if it's advertised among participants of aging conferences etc (or discord, or any other place which fits for serious discussions)

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Vladimir Shakirov

@schw90

9 months

@PauseAI @bindureddy But also: what happens if every single person on earth suddenly gains the ability to design a vaccine and cure against any virus, to detect viruses much better, to improve health nullifying viruses lethality? What if companies use AI to find and fix zero-day exploits first?

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Vladimir Shakirov

@schw90

10 months

@LongevityEVF Nice. If you want to sign a letter with a concrete Call to Action, consider these 2 open letters: 1) on aging, to European Parliament: 2) on aging, to US Congress: They ask for a Moonshot on aging w $20bn/year ($100bn/y from 2030).

Vladimir Shakirov

@schw90

10 months

Sign this open letter to the US Congress by stating your support explicitly in replies to this tweet.

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Vladimir Shakirov

@schw90

9 months

@turchin Who knows. But in this case I'd definitely like if we all publish addendum to Dublin Declaration calling for many $billions on longevity research and on reversible cryopreservation research, and also on scaling the number of cryonics facilities and decreasing their price.

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Vladimir Shakirov

@schw90

11 months

@PeterDiamandis If you give me $1B, I give $100M to Aubrey de Grey, $400M to 100 other life extension enthusiasts to promote topic, and will use $500M to collect 100k support statements from scientists to launch a #MoonshotProjectToEndAging with $20bn/year funding, and to lobby for that Moonshot

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Vladimir Shakirov

@schw90

9 months

@MikhailBatin 3. More funding for organization moments. Not just for science. We need a plan with explicit goal to solve aging. 4. Right people should lead the NIH or Moonshot. People who are passionate about solving aging and age-related diseases.

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Vladimir Shakirov

@schw90

10 months

@GaryMarcus @ylecun However, if AGI x-risks are 10-90% (Jan Leike), ~100% (Eliezer Yudkowsky) or 10-25% (Dario Amodei), we better think twice to use AGI to help us solve aging. The price might be too high, and we probably can try to do that w/o AGI, even if it requires more funding for Moonshots.

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Vladimir Shakirov

@schw90

11 months

@GlamGrafter @yangranat What would the world look like where everyone dies? Not really fascinating. Imagine that aging is solved. I'm sure all problems could be solved in a more civilized way than killing people accordingly to their previous mortality rates.

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Vladimir Shakirov

@schw90

9 months

@MikhailBatin 1. Need more funding. It's most important, everything follows from this. 2. Need a real wide internet-based discussion (slacks, discords, lesswrong-like websites) instead of ceremonial conferences which are an endless sequence of monologues which isn't discussion

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Vladimir Shakirov

@schw90

11 months

@SF_Longevity In my opinion, a large Open Letter to US Congress makes exactly what you write. It's collective influence by (hopefully) a lot of scientists, programmers, artists, etc. It's a perfect cause for any transhumanist to ask any other person on what do they think of Moonshot project.

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Vladimir Shakirov

@schw90

11 months

@Dr_Behrouz @DanilaImmortal While concept of absolute immortality is largely philosophical, the concept of defeating aging and age-related diseases is in my opinion quite sellable. People should have possibility to live healthy as long as they want. Death of old age should be optional.

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Vladimir Shakirov

@schw90

1 year

6/7 Convincing scientific community is the key: once #MoonshotProjectToEndAging becomes an official NIH stance, everything else is straightforward. People trust experts, politicians trust experts. Sadly, experts are largely silent for now.

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Vladimir Shakirov

@schw90

10 months

All four open letters: 1) on aging, to European Parliament: 2) on aging, to US Congress: 3) on cryonics, to European Parliament: 4) on cryonics, to US Congress:

Vladimir Shakirov

@schw90

10 months

Sign this open letter to the US Congress by stating your support explicitly in replies to this tweet.

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Vladimir Shakirov

@schw90

1 year

3/7 Even with only 1000 signatures, it becomes much easier to get new supporters within scientific community (to advance toward 10k, 100k signatures, and establishing #MoonshotProjectToEndAging as an official NIH position), in political circles, and among the general population.

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