Maggie @maggiezli Twitter profile

Last Seen Profiles

@DannyStone8

@7AntonioBello

@StarkMediaTeam

@jandakembangstw

@DaniiQuiiceno

@1956again

@Arisu8495056001

@michael_ayotte2

@pengen_stw

@AminahGie

@tthettiis

@JuliaRobertsTV

@dweek_nhal

@rmcwhorter99

@Mjtpro2014

@Universe817

@Das_90s

@akkivinaya

@Socks_VRC

@KiplangatCasino

@IDemon_1

@voplividchau

@usparasnowboard

@DoctYvonne76064

@suleimamusty

@OrdinalHeros

@KassimDoumbia13

@codeinecrazz

@SangeJanda

@cdowis81

@yovanscape_

@bjk5666640663

@BeauteDevine

@IckyBob_

@Craigtheplague1

@Chroniques225

Maggie

@maggiezli

1 year

why don’t more cs/software eng ppl work on scientific software (esp those that interface w/hardware)?? every other day, I am 🤏 close to losing it over clunky microscopy/etc software and trying to run outdated buggy code

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Maggie

@maggiezli

4 months

How do we move from lab to clinic for an aging intervention in *this* decade? I’ve spent a lot of time thinking about this question and created a framework dubbed the longevity funnel framework (LFF) to answer it:

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Maggie

@maggiezli

4 months

having a roommate who studies real physics/math is so humbling her bookshelf gives me anxiety LOL

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Maggie

@maggiezli

3 years

so stoked to share that I'll be joining @beondeck catalyst as a fellow this summer! very excited to learn and grow in such an incredible community ✨ many thanks @shriyanevatia @ani_pai @katarinamsmith for the opportunity

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Maggie

@maggiezli

7 months

it is unbelievable how much better some random youtube tutorials are at teaching than uni (and they manage to teach better in a foreign language I don't understand too)

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Maggie

@maggiezli

11 months

very grateful for your support on this project, would not have been possible otherwise, thank you very much @tylercowen !! one of the fastest granting programs ever, do apply if you have a project you’d like to work on longer-term :)

tylercowen

@tylercowen

11 months

Emergent Ventures winners, 27th cohort:

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Maggie

@maggiezli

10 months

impromptu event to intro more students to longevity and aging biology research!! lots of interest + talent in toronto, just sayin’

Nathan S. Cheng thinks you should work on aging.

@realNathanCheng

10 months

Packed house at Toronto Longevity Night at U of T! 🇨🇦🧬

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Maggie

@maggiezli

9 months

honoured + very excited to be a Time Fellow!! thank you @c_hudpaz for this incredible community 🫶

Time Initiative

@time_initiative

9 months

🚀 Introducing our 2023 Time Fellows! These trailblazers are gearing up to redefine the future of aging research. Exciting times ahead as they embark on this transformative journey! Check out the faces behind the brilliance. 🌟 #TimeInitiative #aging #agingbiology

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Maggie

@maggiezli

6 months

i cannot wait to do absolutely nothing and everything after exams

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Maggie

@maggiezli

6 months

this will be the first event of its kind in toronto, come!! the team worked hard to make the event free to join :) we're targeting students (undergrad to grad), but all are welcome

Toronto Longevity Research Circle

@tlrc_info

6 months

Join us on Jan 31 for the inaugural Toronto Aging Biology Symposium: 🧬 Internationally recognized leaders and scientists will cover topics on longevity research, clinical translation, startups and VC 📝 Sign up (free!) for talks/panels + networking from 9am to 4:30pm

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Maggie

@maggiezli

9 months

truly, an incredible time to be alive! very lucky to be on such a mission-driven team I personally care about the field a lot and I think you should too :)

Alex Colville

@AlexJColville

9 months

Why don’t we target the inevitable cause of our decline, aging, before it happens? Excited to announce a moonshot fund to catalyze the longevity field to new heights. We won’t stop until we all have agency over how long we can live in good health.

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Maggie

@maggiezli

7 months

@internshipdude bruh talk to ppl irl pls

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Maggie

@maggiezli

3 months

group projects in school are either a blast or a painful reminder how much of a blessing it is to work with competent ppl who actually care about their work

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Maggie

@maggiezli

9 months

today I pretended to not be an eng student w/a tetris looking calendar I’ve been missing out on this all along wtf??!

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Maggie

@maggiezli

4 months

@sincethestudy this is so good and actually performs for biology and niche topics, damn some other model tuning besides presenting info hierarchy that would be useful: - dev timelines (but nonlinear, think tech trees) - market maps - for niche topics: find SOPs, guide experiment design, etc

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Maggie

@maggiezli

5 months

adding more early talent to the longevity community from toronto :) was lots of fun putting together this event, thank you to everyone who supported us along the way + joined the day of!

Toronto Longevity Research Circle

@tlrc_info

5 months

On Jan 31, we hosted the Toronto Aging Biology Symposium, the first event of its kind here featuring scientists and leaders in longevity + regen medicine research! We’re proud to have hosted 200+ attendees including undergrad/grad students, alum, and industry professionals:

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Maggie

@maggiezli

1 year

dealing with visas is so unnecessarily 😐

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Maggie

@maggiezli

9 months

prof just went “many of you will die from cancer anyways, who cares” SIR I CARE

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Maggie

@maggiezli

7 months

also has immense potential for long-term savings on healthcare costs and quality of life improvements for individuals/their caregiver(s) + there is a lot of nuance re: accessibility, but a next step would be to turn this could into a can

age1

@age1vc

7 months

We found that a drug approved and indicated for aging would conservatively have a peak global market size ~$150-$200 billion annually. A company that owned only this drug would be more valuable than the top 2 big pharma companies (J&J and Pfizer) in terms of revenue…combined.

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Maggie

@maggiezli

9 months

me @ some things more so than actual ppl 🫢

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Maggie

@maggiezli

8 months

more wholesome moments from an unforgettable weekend:

Carol

@_Carol_Mag

8 months

It is *so* special to have friends who share your passions. The @time_initiative retreat this weekend was just a reminder that the future is bright, and we get to build it. Thank you @c_hudpaz for making this happen.

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Maggie

@maggiezli

11 months

hey look it’s me (and I still wonder why my neck hurts)

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Maggie

@maggiezli

5 months

working with people who truly care about something goes *such* a long way so grateful to have discovered shared research interests via a random convo, from which one thing led to another exhibit A (the paper link that started it all):

David He

@realDavidHelium

5 months

So grateful for the opportunity to co-host TABS2024 with my amazing friend @maggie_1i . What started as our journal club @tlrc_info , we wouldn’t have thought this event would’ve happened so soon. Thank you to our astounding speakers who made this possible! (some missing below)

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Maggie

@maggiezli

1 year

someone pls make better (non invasive) clinical diagnostics AND treatment methods for endometriosis the fact it’s so bad for some, to the point where you’ll pass out from the pain, is outrageous to me

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Maggie

@maggiezli

3 months

somewhere on the internet lies a niche website littered with ads that has the exact info you need (or a questionable youtube video with <100 views)

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Maggie

@maggiezli

2 months

it’s finally not cold af in toronto who knew having the sun out would solve half my problems

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Maggie

@maggiezli

3 months

@LauraDeming these ones :) - intro to qc + qm: - interactive lin alg: - systems medicine lec notes: - linear physical systems analysis:

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Maggie

@maggiezli

1 year

help 🆘

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Maggie

@maggiezli

4 months

Read the LFF here:

What we wish we knew entering the aging field

The longevity funnel framework (LFF)

www.librariesforthefuture.bio

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Maggie

@maggiezli

1 year

who knew cell counting was so involved (sounds trivial but error rates are so high) + the way almost everyone still counts manually?!! am also mind-blown by how good a trained biologist’s eye is, they just look and know dead/alive etc, but they look the same 😭

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Maggie

@maggiezli

6 months

2024 is going to be the yr I finally organize my bajillion tabs everywhere + clear my reading list 😌

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Maggie

@maggiezli

1 year

today my dad insisted I jailbreak an old iphone for him so he can mess w/carplay features and “put my eng degree to good use” 😭

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Maggie

@maggiezli

5 months

crazy crossover episode (now I can yap to friends who yap on hrs about film)

Celine Halioua

@celinehalioua

5 months

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Maggie

@maggiezli

1 year

apply + share!! (personally love that coming from a bio background isn’t a requirement here; I think the field can benefit from more people with tangential backgrounds like engineering and cs)

Time Initiative

@time_initiative

1 year

Create a healthier future for all of us. 🌍 Apply for the Time Initiative Fellowship and join the next wave of leaders in #AgingBiology . Deadline: June 30th. Watch and share with the ambitious #undergrads you know! #TimeInitiative 🎥 full video:

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Maggie

@maggiezli

8 months

I love learning (hallucinating) new concepts on exams 😇

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Maggie

@maggiezli

11 months

can someone pls make outlook better (chrome extension or smthing) bc I die a little bit inside every time I open my school email and try to keep track of things and who designed the feature where the email self destructs once you respond to a calendar invite LIKE WHY

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Maggie

@maggiezli

4 months

new method to do work: > forget charger > still go to library > speedrun work bc laptop has negative battery life > wpm 📈📈 > repeat

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Maggie

@maggiezli

4 months

I referenced the work of lots in the writing process, especially those who have extensively compiled and summarized information (thank you!) Credit is always due, so here is a spreadsheet compiling all the resources I found helpful:

Longevity resources

Longevity resources Title,Category,Description,Link Longevity FAQ: A beginner's guide to longevity research,Blog,The original longevity FAQ with data on 95 compounds/methods that increase mouse...

docs.google.com

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Maggie

@maggiezli

11 months

catching up with grandparents is always so heartwarming but also so heartbreaking at the same time

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Maggie

@maggiezli

4 years

s/o to @qosfoundation for running the mentorship program that kickstarted this project/contribution!! @sukin_sim , thank you for being such an incredible mentor and @lanabozanic , thank you for being an awesome quantum buddy <3

PennyLane

@PennyLaneAI

4 years

Thanks to @lanabozanic @maggie_1i @sukin_sim for their awesome tutorial contribution to the QML gallery! Encourage everyone to check it out. Accelerating VQEs with quantum natural gradient

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Maggie

@maggiezli

11 months

petition to minimize light pollution so the stars are bright af at night (or get rid of it somehow)

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Maggie

@maggiezli

1 year

watching the engineers vs biologists (by “training”) argue about how to design/do experiments everyday is peak entertainment + pretty insightful perks of being in an interdisciplinary lab!

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Maggie

@maggiezli

1 year

was cleaning out my 17262737 google drives and found this from grade 7??!!!! it’s so ironic given I avoided physics/math like the plague in high school, yet apparently interest in these topics started earlier funny how life works out (still allergic to proofs tho)

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Maggie

@maggiezli

4 months

Aging is highly variable across space and time (and complex!)

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Maggie

@maggiezli

24 days

incredibly exciting tech (+science) in reversible cryo!!

Laura 🌲 ⛰️

@LauraDeming

24 days

Introducing @cradle_health , co-founded with @huntercoledavis . We're building reversible cryo technologies. Think the hibernation pods you see in space movies for long-term travel - we want to build that. We’ve raised $48M, built a world-class team of scientists and engineers,

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Maggie

@maggiezli

4 months

such an important piece from @_Carol_Mag that highlights something often overlooked in aging: the rate of decrease in follicle # is ridiculously fast — few other systems in the human body start rapid decline so early

Carol

@_Carol_Mag

4 months

Why has menopause become a normal part of every woman's life, when it causes unnecessary suffering? Why is reproductive aging research still significantly underfunded when half of the population experiences menopause? I believe this *needs* to change, so I wrote a piece about

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Maggie

@maggiezli

4 months

every time i count cells by hand i die a little bit on the inside

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Maggie

@maggiezli

8 months

the b in bme is not doing any bme-ing as of late (in class)

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Maggie

@maggiezli

6 months

the amount of nostalgia that hits catching up with ~decade long friends is crazy (almost enough to prematurely launch myself into a quarter life crisis)

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Maggie

@maggiezli

10 months

how is summer almost over already this is so upsetting

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Maggie

@maggiezli

11 months

summer was supposed to fix my overconsumption of coffee but iced coffee is too ✨🤌

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Maggie

@maggiezli

10 months

caffeine dependency about to hit an all time high ☕️🍵

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Maggie

@maggiezli

4 months

Possible interventions can be categorized as - 1st gen = delay aging - 2nd gen = replace, restore, or pause

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Maggie

@maggiezli

11 months

figuring out how to present data nicely is a pain I’d never thought would be so time consuming doesn't help I’m always endlessly messing with the colour/font/spacing/everything when plotting things 🥲

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Maggie

@maggiezli

1 year

+ I’ve noticed companies that do make (ugly) GUIs in this realm charge ridiculous $$ for the tiniest updates, after an already overpriced initial overhead/setup cost

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Maggie

@maggiezli

10 months

@realNathanCheng @realDavidHelium @ydeigin @ShiftBioscience @TheShayanRabbi @MbD_UofT and this (see img) is precisely why I think we need more students interested and involved, across *all* disciplines the talent problem has yet to be solved!

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Maggie

@maggiezli

4 months

Targeting aging = healthy lifespan extension for more units of health + more units of time

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Maggie

@maggiezli

2 months

finals = tree slaughter season

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Maggie

@maggiezli

10 months

oppenheimer was so jarring I tripped two times on my out still not over it omg

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Maggie

@maggiezli

1 year

ok last one on this run of nostalgia drew this in grade 6 to tell my parents I didn’t like their parenting methods 😭 (inspo from german comic vater und sohn)

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Maggie

@maggiezli

9 months

@floguo git clone personality first 🫡

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Maggie

@maggiezli

10 months

thank you to speakers @realNathanCheng @realDavidHelium @ydeigin and Brendan Swain ( @ShiftBioscience ) for inspiring students :) h/t @TheShayanRabbi for pulling lots of weight on organizing + this wouldn’t be possible without Human Biology Student Union and @MbD_UofT !!

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Maggie

@maggiezli

1 year

3D printer is doing its thing!!

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Maggie

@maggiezli

9 months

tdy I found a signed copy of scherman and dalton’s take on andy warhol for 2 dollars I should break routine more often damn

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Maggie

@maggiezli

4 months

“all models are wrong, but some are useful” (look at the statistical power of studies)

Alex Colville

@AlexJColville

4 months

2) The study is likely grossly underpowered at 20 mice per group, esp for small effect size. Underpowered studies can lead to a low positive predictive value.

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Maggie

@maggiezli

4 months

Finally, measures of aging need to capture function, feeling and survival for clinical relevance. Possible endpoints should inform the design of biomarkers and proof of concept measures:

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Maggie

@maggiezli

4 months

(engineering doesn’t count)

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Maggie

@maggiezli

1 year

highlight of the day was spending ten mins after an uber ride exchanging local food recs with the driver 10/10 would recommend

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Maggie

@maggiezli

11 months

do y’all ever think so hard that you kind of dissociate on the spot

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Maggie

@maggiezli

10 months

@sincethestudy if I did this, I would be the joke LMAO

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Maggie

@maggiezli

4 months

Preclinical models relevant for aging range across in silico, in vitro/ex vivo, and in vivo

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Maggie

@maggiezli

9 months

(very^10000) excited!!

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Maggie

@maggiezli

29 days

friends who bring you stuff from halfway across the world are so precious

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Maggie

@maggiezli

1 year

never thought I’d be CNC machining but alas

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Maggie

@maggiezli

10 months

walking through a chain of citations to dig up the “original” pre-2000s paper is an absolute pain internet sleuthing taken to another level

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Maggie

@maggiezli

4 months

1st gen approaches will pave the way for an aging indication. The scientific moonshots where we can observe a much larger effect size for healthy lifespan extension will likely be 2nd gen approaches!

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Maggie

@maggiezli

1 year

two life essentials: pressure cooker + air fryer 😌

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Maggie

@maggiezli

11 months

I've been LK-99 rabbit-holing nonstop but I should be focusing on my lab work oops

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Maggie

@maggiezli

11 months

finally made plans for a barbieheimer movie day with friends except the barbie part is just so I can pull out the brightest possible outfit from the depths of my closet

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Maggie

@maggiezli

4 months

@sincethestudy at this rate, you could phase out most lit reviews LOL

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Maggie

@maggiezli

5 months

bonus photo with rep from @age1vc and @time_initiative !!

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Maggie

@maggiezli

10 months

@jaegpark idk how to put it nicely so I’ll just leave it at: bro is in the wrong arena and one w/no grass to touch

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Maggie

@maggiezli

1 year

the difference in govt funding here is just... for some quick #'s, NIH's (US) funding for dementia/Alzheimer's research was ~59x CIHR's (Canada) in 2021

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Maggie

@maggiezli

6 months

@nabeelqu @tylercowen would be cool to do a map to visualize where ppl tend to cluster!!

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Maggie

@maggiezli

11 months

iOS has a clamp 🗜️ emoji but not a cell emoji LOL?? (the microbe 🦠 one doesn’t count)

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Maggie

@maggiezli

8 months

the weather has become cold too soon 🫥

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Maggie

@maggiezli

2 years

cool preprint on information theory x homeostasis wrt aging!!

The fidelity of genetic information transfer with aging segregates according to biological processes

Maintenance of cellular function requires highly coordinated communication between trillions of biomolecules. However, over time, communication deteriorates, thereby disrupting effective information...

www.biorxiv.org

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Maggie

@maggiezli

7 months

chatgpt for simulink plssss

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Maggie

@maggiezli

11 months

has anyone looked extensively into using fruit peels/composite materials (to create adsorbents, membranes, biochars, etc) for absorption of heavy metals from water? it (naively) feels like an underlooked area; kinetics of absorption are not well understood or characterized

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Maggie

@maggiezli

9 months

there's a post floating around on HN, go find it!! you'll get an axolotl-themed gift + an age1 sticker from me if you are one of the first few to find it and upvote (send me ss) 🤭

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Maggie

@maggiezli

3 months

optical tweezers ftw (useful for biological applications too!)

Anastasia Marchenkova

@amarchenkova

3 months

It feels like things are accelerating in quantum hardware. A tweezer array with 6100 highly coherent atomic qubits.

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Maggie

@maggiezli

11 months

@izzygrandic some internet essays on this topic I like: - - - -

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Maggie

@maggiezli

1 year

@jennifertsai_ @Sana_Rfzz love this! my only feedback is to add in some aging related fellowships/communities, @time_initiative + @LBF_org come to mind :)

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Maggie

@maggiezli

11 months

is growing up getting the responsibility for bookings even on vacay with parents (it’s literally the most anxiety inducing part) “you can book things bc it’s faster if you do it” “wait actually would be great if you just plan the whole thing”

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Maggie

@maggiezli

11 months

@celinehalioua thank youuu!! and I am very lucky to have had the opp to intern at Loyal, a big part of the reason I got into longevity/aging bio :)

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Maggie

@maggiezli

10 months

@jaegpark not strictly for/against dating apps, but at least they have some hint of consideration for females (this doesn’t)

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Maggie

@maggiezli

1 year

overheard today: “bro is bored at the conference so he’s spamming me with photos of company booths with captions roasting them” 💀 one man shark tank, lab edition

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Maggie

@maggiezli

11 months

roommate just called broken spaghetti discontinuous pasta and I cannot unsee it now, there are limits in my pasta 😩

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Maggie

@maggiezli

10 months