Equity is an afterthought in tech development, typically arising only after unfair public outcomes are realized - high prices of new drugs, biased AI-algorithms, failure to develop therapies for rare diseases - a cultural shift is needed:
@ScienceMagazine
I am honored to become the new
@AAAS
president-elect. I look forward to bringing a renewed focus to scientific literacy, diversity, and impact to the organization.
Students & postdocs are justly distressed about the support they receive during their training. It’s not just the inadequate funding. In my letter to
@NewsfromScience
I suggest reforms in academia’s culture & governance that position trainees at the center
"Human Nature", a superb film that frames
#CRISPR
technology and explores its use and social/ethical issues, will premiere on
@PBS
September 9 at 8 pm.
Need something uplifting to watch this weekend? "Human Nature", a superb film that frames
#CRISPR
technology and explores its use and social/ethical issues, now streams on demand
Here
@UCSF
, a CRISPR tool is being developed to detect
#COVID19
infection.
I'm honored to run for President-elect of the American Assn for the Advancement of Science (
@aaas
), which promotes diverse, responsible science. Vote for President-Elect until April 21.
Superb science from
@kevansf
@UCSF
-- congratulations! This breakthrough epitomizes the continuum of research, where fundamental discoveries fuel
#PrecisionMedicine
.
#PrecisionMedicine
extends far beyond genomics.
@UCSF
, we have shown that a multi-directional flow of information across basic, translational/clinical and population sciences creates new insights across the spectrum of healthcare and biomedical research.
Help wanted, scientists need apply! To ensure effective, equitable & inclusive advances in a world being transformed by science and technology, we need scientists doing science of course, but also embedded in every influential sector of society. My editorial
@ScienceMagazine
"The world is continuously being transformed by science and technology, but to deliver equitable benefits to the public, scientists must be embedded in influential sectors of society," argues
@AAAS
President
@kryamamoto
in a new
#ScienceEditorial
.
I had the honor of chairing this report, an ambitious vision for an enhanced
#NIH
that seeks and rewards bold science and supports well-conceived, broadly-scoped initiatives, including
#PrecisionMedicine
!
I invite you to take a look:
@CLS_Advocates
Imagine combining – on a single computational platform – all findings about normal and aberrant biological processes, from human populations, to individuals, to experimental organisms, to cells and molecules.
That’s
#PrecisionMedicine
Read the story:
These two fantastic gifts will launch a myriad of discoveries by supporting bold basic research ideas as well as our most innovative graduate students. Immensely grateful to the visionary donors who made this possible.
Congratulations to
@UCSF
colleague and
#NobelPrize
Laureate Dave Julius
@DJuliusSF
, and many thanks for treating us all to his thrilling, inspired research!
“A new agreement simplifies and reduces the cost for UC personnel to publish their work in the full suite of
@PLOS
journals. This is a strong institutional statement in support of open access. Congrats UC!”
@UC_Newsroom
Nevan Krogan,
@kevansf
& team discovered SARS CoV-2 rewires kinase pathways & exits via filopodia ➡️ potential COVID-19 therapeutics incl. 10 already FDA-approved. Great example of the power of
#PrecisionMedicine
connecting basic research & health care!
Pleased to be
@WhiteHouse
for discussion of Biden’s Executive Order on National Biotechnology & Biomanufacturing Initiative -> translate bioscience discoveries/tech into medical breakthroughs, stronger US supply chains & more, valued at $30trillion by 2030
Open science enables & empowers a global, diverse community to contribute to science - see Steps Toward Equitable Access in Microbiology by
@RMBurckhardt
@ASMicrobiology
. I share thoughts on revisions to systems, approaches to make open sci more equitable
AAAS applauds the nomination of
@bertagnollimm
as the next NIH director. Her unique combination of credentials and personal experience make her "simply put...the director NIH need now." Read our full statement here:
Excited to be testifying to the US House Committee for Energy and Commerce tomorrow am at 7:30am PST on, “ARPA-H: The Next Frontier of Biomedical Research". Watch along here.
Congratulations to Gretchen Kiser who built
@UCSF
’s superb
@UCSF_RDO
from the ground up and shapes many other activities that advance the richness and diversity of our research endeavor. Her work created a national model, as recognized by this
@NORDP_official
leadership award.
We need scientists to be involved in shaping government policies – to use their science expertise to help define how things get done, who does them, who benefits, who pays, and how much.
Students/advocates welcome. Apply within!
This is a
@UCSF
-led 7-institution/21-investigator transdisciplinary precision medicine approach to understand and combat the effects of childhood adversity. Thankful for the vision of the CA Initiative to Advance Precision Medicine
#CIAPM
and for this award.
Dr. Thakur and team will further our understanding of which children are most vulnerable to the effects of ACEs, what factors provide buffering protection, and which interventions most improve child and family outcomes.
The crowning significance of
@UCSF
’s continued primacy in
#NIH
funding is not merely the dollars, but the excellence, innovation, and impact of our research. Great work, all!
#UCSFProud
Academia, funders and the private sector must recognize the urgency to take immediate, bold, quantifiable actions to
#diversify
our scientific community. We all must advocate and participate.
It was great seeing colleagues from all over the world, celebrating science at 2024
#AAASmeeting
“Toward Science Without Walls.” Science & tech would proceed faster, better in an ecosystem free of barriers that currently separate us - Recap & Video
@aaas
The promise of
#PrecisionMedicine
will become reality through a knowledge network that yields the seeds for new discoveries, better outcomes, and greater value and equity to improve health for all. Read more at and follow
@UCSFPrecision
This
@NSF
award will expand SPOKE’s capacity to do what the human brain cannot – integrate vast amounts of biomedical information into a discovery engine that will lead to new discoveries and ultimately therapies.
#PrecisionMedicine
@UCSF_BCHSI
We must put science and technology at the top of the political agenda this year. What happens next will define America’s future. This is not hyperbole. It’s science.
Please join
@SciTechAction
@MaryWoolleyRA
and me in calling for crucial science funding.
The costs of not increasing spending on S&T are stark, but the appropriations process may offer an opportunity to bolster capacity & global competitiveness.
@SciTechAction
co-chairs
@kryamamoto
&
@MaryWoolleyRA
discuss in
@thehill
:
This 2-day, public webcast summit explored the ways in which systemic
#racism
and other barriers impede
#STEMM
careers for historically marginalized racial/ethnic groups, and strategies to address these barriers. PDF available as free download via
@theNASEM
Published in
@NatureBiotech
,
@UCSFHospitals
neurosurgeon Philip Starr & colleagues describe the first human use of a
#DBS
device that allows chronic wireless streaming of brain activity at home. This is the first step towards adaptive DBS for
#Parkinsons
:
BRIDGE is a spectacular tool that connects multiple data sources and delivers actionable visualizations to the physician and the patient.
Read more ➡️
#PrecisionMedicine
@Rankin_Lab
@UCSFPrecision
I'm inspired by the 23 projects funded in this ultra-rapid call for proposals and confident that the knowledge gained and technologies developed will help address not just the
#COVID
-19 pandemic, but prepare us for other infectious diseases going forward.
A pleasure to be at the
@WHOSTP
w/ Director Arati Prabhakar to discuss the outstanding work in her office to ensure equity in development of science & technology innovations, to implement the President’s Biotechnology & Biomanufacturing Executive Order
It's been an honor to co-chair the National Academies Committee on Emerging Science, Technology, and Innovation in Health and Medicine. Join me
@NASEM_Health
on 8/22 for a public webinar on our new report exploring equitable innovation in health & medicine
This is going to be a fantastic program that will help to bridge institutional silos and lead to new breakthroughs in the health and data sciences.
#PrecisionMedicine
@UCSF_BCHSI
@Idasim
"Many patients and patient populations face risks to their health from the use of data that are incomplete, data systems and infrastructure that are not well connected, and inherent bias."
@Idasim
@UCSF_BCHSI
#PrecisionMedicine
In our latest News and Views: Marina Sirota and colleagues
@UCSF_BCHSI
discuss new data on the application of
#machinelearning
to personalisation of routine laboratory tests
@msirota84
Thank you,
@PTurnbaugh
. Really enjoyed talking to you about my background and the origins of my firm belief that being a scientist involves more than just doing experiments and trying to learn something cool!
For
#PrecisionMedicine
to work, we have to make it more racially diverse, technologies more accessible, and we have to develop and hire a diverse workforce.
@PMWCintl
Creating a dynamic flow of information across research, health, and health care is fundamental to
#precisionmedicine
. It was great to engage
@JoelBabdor
's interest and expertise in that effort.
"Human Nature" is an extraordinary documentary for non-scientists and scientists alike on the excitement of discovery, the power of
#CRISPR
technology, and the complexities of its societal implications. In theaters soon!
Join me and Peter Walter discussing how
#PrecisionMedicine
integration of basic and clinical investigation motivated
@UCSF
scientists to pivot their research to confront
#Covid_19
only to encounter the “valley of death."
Jan. 25, 8:00am
#PMWC21
@PMWCintl
Excited to have this conversation with
@drhpaz
whose enormously broad experience across the expanse of the health care spectrum provides a clear view on how to think about the payer's perspective in
#PrecisionMedicine
.
@PMWCintl
#Covid_19
is bringing the world research community together to address the pandemic. Join me at this virtual, no-fee conference January 25-27
@PMWC
to hear from top scientists across academia, industry, and government.
.
@DavidAKesslerMD
has been serving as a top pandemic advisor to Biden through the transition, along with
@UCSF
colleagues
@DrEricGoosby
and Dr. Robert Rodriguez.
Not only will clinically relevant results be returned to individual patients, but the data will also serve as a unique and invaluable resource to the research community.
#PrecisionMedicine
#Genomics
#DataScience
This is an essential conversation for us to have - the
@ucsf
Institute for Human Genetics (IHG) has launched a standing Committee on Genetics and Society to address such critical topics, which met yesterday for the first time
For America to meet the challenges of the 21st century, the federal government must commit to increasing federal spending on research and development, finally breaking out of the cycles of neglect that have undermined our capabilities and imperiled our global competitiveness.
Just out:
@UCSFPrecision
newsletter February issue, includes a report from
#PMWC21
, a link to our new video, and a spotlight on the work of our colleagues
@UCDPrecisionMed
. Take a look:
President Biden has made a superb choice in nominating Arati Prabhakar as Director of the Office of Science and Technology Policy
@WHOSTP
& Science Advisor on the Cabinet: Dr. Prabhakar is bold & insightful, will ensure that the US S & T enterprise thrives
It was memorable to attend this Peace Plaza event w/
@TeamPelosi
&
@LondonBreed
– my parents happen to grow up close to this spot in Japantown. Thankful for the support of the plaza revitalization - one of only three remaining historical Japantowns in the US.
San Francisco’s Japantown Peace Plaza speaks to our city's unity to
#StopAAPIHate
and embrace of our beautiful diversity.
Community leadership in its revitalization ensures that it will remain a beacon of hope for our city and for visitors from around the globe. -NP
WOW! Congratulations to
@UCSF_BCHSI
faculty member Hani Goodarzi (
@genophoria
) for winning the
@Vilcek
Prize for Creative Promise in Biomedical Science! Congratulations!
This powerful new
#AI
tool from a
@UCSFCDHI
-led collaboration will enable secure and efficient data access to advance
#PrecisionMedicine
across patient populations, socioeconomic groups, and geographic locations.
Pharma spends $2.6B to find a new
#antibiotic
. Peg Riley says “give me $200, an undergrad, and a couple of weeks”, and she’ll find a reagent that specifically kills any bacterial pathogen. What’s the disconnect? Check out this interview.
#precisionmedicine
#PMWC20
Worried about COVID-19? The spectrum of a "post-antibiotic era" is far scarier. In this lively conversation at
#PMWC20
, Prof. Margaret Riley
@UMassScience
talked with
@kryamamoto
about antibiotic resistance and a path forward.
#Pharma
: are you listening?
.
@UCSF
researcher Peter Walter pivoted his research to create a novel, inexpensive preventative & treatment for COVID_19, only to encounter the “valley of death.” Hear his and other stories of disruption with
@kryamamoto
@PMWCintl
Jan. 25, 8 am, FREE registration
#PMWC21
ICOR’s first public webinar is May 17 10:30am-12pm ET. Jam-packed agenda with reports on research-on-open-research and open science best practices. Please join us by registering here:
Looking forward to the "UC Precision Medicine Programs: Achievements and Challenges" panel tomorrow at
@PMWCintl
(June 28, 9:15AM, back in-person) w/ Chair
@SelectAgent
, Clare Lajonchere and Fred Meyers:
Precision Population Health is a core element of
#PrecisionMedicine
. COVID-19 has made clear that defining social determinants and linking them with biological data is critical in order to improve health for everyone.
Join the California Initiative to Advance Precision Medicine Advisory Council meetings tomorrow & Friday via Zoom. The council will oversee the distribution of State funds to advance
#PrecisionMedicine
to benefit the people of California.
@Cal_OPR
The integration of concepts, approaches, data and outcomes that emerges from these projects is the essence of
#precisionmedicine
.
Truly grateful for the vision and generosity of George and Judy Marcus in creating and maintaining this unique resource.
The brilliant and dedicated work of grad students and postdocs fuels
#science
. Their energy and determination to set aside their own projects, and pivot to make new discoveries about SARS CoV-2 and to combat
#Covid19
, is inspiring and impactful.
"When I learned about what was happening at the
@czbiohub
across the street, I jumped at the opportunity; here is something where I could offer my time and expertise.”
@rig_atoni
@HanaScientist
@altos_labs
Enormously exciting to see Altos Labs come to fruition, with you and other superb investigators exploring rejuvenation, a scientific frontier. Very best wishes!!
An essential element of
@UCSF
’s mission is to serve the full spectrum of San Francisco’s incredibly diverse population. In doing so, we are at the same time accumulating a rich trove of data that will advance us toward
#PrecisionMedicine
for all.
To be effective in bringing care and resources to local communities requires broad and deep engagement that builds trust over time. Read about
@UCSF
's many partnerships with local community organizations:
Rather than just looking at individual genes, whole genome sequencing analyzes a person's entire genetic information. This could be a game changer not only for an individual, but for our growing knowledge network, which is the basis of precision medicine.
NIH today announced contracts with companies and universities to develop digital health solutions to help address
#COVID
-19 pandemic
@theNCI
@NIBIBgov
@KBibbinsDomingo
@edyong209
Great piece. I wish it would have mentioned that without decades of taxpayer-funded basic science research on seemingly obscure topics such as coronaviruses, T7 RNA polymerase, transfectiion, RNA mods, innate immunity and others, we would not have the vaccine we have today.
Congratulations to Bakar institute affiliate Dani Ushizima,
@dani_lbnl
, for being named one of ’25 Women in Science in Latin America’!
#womeninstem
#WomensHistoryMonth
Read more about her amazing research:
Congratulations to Sawona Biswas, our genetic counselor extraordinaire
@UCSFHospitals
@UCSFPrecision
for her contribution to the new document showing clinical utility of exome or genome sequencing in pediatric care
The capacity to fully implement
#PrecisionMedicine
will largely depend on what insurers will reimburse. Join me to gain insights from
@drhpaz
on the current perspective of payers.
Pleased that
#precisionmedicine
is getting attention - my paper with
@PersonalizedMed
is one of most cited recent papers in Health Affairs w/ 146 citations to date and helped journal get highest impact score ever. Precision Medicine: From Science To Value