SIRS names Sir Robin Murray the 2020 Lifetime Achievement Awardee. See the full announcement and release at . Thank you for your contribution to the advancement of schizophrenia research!
@KingsIoPPN
#Schizophrenia
Today on
#WorldSchizophreniaDay
, we are highlighting our core value to eliminate
#stigma
. People with a diagnosis of
#schizophrenia
, just like people with any other adversity, deserve to be treated equally, fairly, and be fully included in society.
-
@SIRS
is proud to welcome
@m_nordentoft
as the new SIRS President! We thank
@TilWykes
for her leadership over the last two years. And we look forward
@paola_DZN
continued service to the society as President-Elect.
#SIRS2022
Feelings of social exclusion and
#loneliness
predict increases in
#paranoia
over time, according to a new study
@SchizRes
: Cognition. Social exclusion and loneliness may be useful targets in the treatment of paranoia.
Can exercising reduce symptoms in schizophrenia? This network meta-analysis suggests that aerobic exercise, as an adjunct treatment, may be effective in reducing overall symptom severity and alleviating negative symptoms.
One of the core values of SIRS is our commitment to fairness, diversity, inclusion, & equity. We are committed to hosting our US meetings in states that espouse these same values. Please see our statement on the recent U.S. Supreme Court decision.
#SIRS
has awarded the 2022 Research Harmonisation Award to the convener Amy Pinkham, Ph.D. from the University of Texas at Dallas. See the full announcement on our website. Congratulations to Professor Pinkham and the rest of the group!
Data analyzed from 15 studies found that 33% of people with first-episode
#psychosis
experience visual hallucinations, suggesting that these are relatively common
Predicting
#psychosis
6 years later in clinical high-risk state using plasma proteomics and demographic data: A study
@JAMAPsych
reports promising proteomic biomarkers and suggests early dysregulation of the complement and coagulation cascade. doi:10.1001/jamapsychiatry.2020.2459
A new study
@EClinicalMed
from
@KingsIoPPN
reports real-world long-term outcome of individuals at high risk for
#psychosis
up to 12 years: They may need longer care beyond a few years.
🔬New research from NAPLS2
@SchizRes
analysing data of 349 individuals at clinical high risk for
#psychosis
(CHR) shows that decline of social function in adolescence predicts conversion to
#schizophrenia
and poorer prognosis.
💊 Amisulpride appeared to be more efficacious in PANSS score reduction than aripiprazole or olanzapine in head-to-head pragmatic, rater-blind, randomised trial in
#schizophrenia
.
@TheLancetPsych
🔬An interesting update of the glutamate hypothesis of
#schizophrenia
from Egerton and colleagues integrates perspectives from neurodevelopmental models, neuroimaging and drug development.
@SchizRes
@KingsIoPPN
#psychosis
Schizophrenia is associated with cognitive difficulties, but there are few measures adapted for low- and middle-income countries. New study
@SchizBulletin
presents a culturally sensitive cognitive battery for schizophrenia in Ethiopia.
New study in
@SchizBull
highlights a potential association between cannabis-use and relapse following a first-episode of
#psychosis
regardless of medication/treatment adherence.
.
@schizjournal
using a 7-tesla MRI, researchers
@UniMelb
revealed that patients with
#schizophrenia
have higher brain iron levels in dorsal
#striatum
and distinct iron distribution, which may be associated with abnormal dopaminergic activities.
#SIRS
awards the 2021 Research Fund Award to Dr. Vuyokazi Ntlantsana from
@UKZN
in South Africa. Dr. Ntlantsana will implement a culturally appropriate behavioral tool to ameliorate disability caused by trauma &
#psychosis
in South Africa.
#schizophrenia
The SIRS First-Episode Psychosis Research Harmonisation Group is looking for input from a wide range of perspectives, including people with lived experience, caregivers, advocates, clinicians, & researchers. See the details & the survey at
@VelingW
Prepare to be inspired at the
#SIRS2022
Congress. Learn and discover at the plenary session with Nev Jones
@viscidula
from the University of Pittsburgh
@PittSocialwork
on Saturday, 9 April. The early registration rate ends on TODAY (22 Feb)!
#schizophrenia
This article by Marder and Umbricht
@SchizRes
provides an overview of emerging measurements, pathophysiological understanding, and treatments for negative symptoms in schizophrenia.
In a recent double-blind, sham-controlled pilot study, Bation et al found that iTBS over the left DLPFC can alleviate negative symptoms of
#schizophrenia
. This effect might be related to a significant modulation of dopamine transmission.
@Nature_NPJ
In a recent article in
@SchizBulletin
, Pierce provides a first-person account of the treatment of negative symptoms of schizophrenia with transcranial magnetic stimulation.
Check out the new 'Making a Difference' Research Stories page on our website.
#SIRS
members share how research has helped people with the diagnosis of
#schizophrenia
. Our 1st post is from E. Fuller Torrey, 2021 Lifetime Achievement Awardee
@efullertorrey
What may be behind distress when experiencing derogatory and threatening voices (DTV) in psychosis? New cross-sectional study
@SchizBulletin
identifies 7 factors that lead individuals to listen or believe DTV.
We will have a fantastic group of keynote and plenary speakers at the virtual
#SIRS2021
Congress on 17-21 April. Check out their topics and bios at . Whose presentation are you looking forward to hearing?
🔬 New study
@TheLancetPsych
reports reduced cancer screening rates in people with mental illness, especially women with schizophrenia. This is despite the increased mortality from cancer in this population:
#SIRS2021
Day 2 begins in an hour with Plenary Session 1: How to Translate Scientific Findings on Emotional Information Processing to Psychological Interventions for People with Psychotic Disorders with Tania Lincoln.
@ProfTanLincoln
Israeli study finds that people with
#schizophrenia
were less likely to test positive for
#COVID
-19, but 2x more likely to be hospitalized and 3x more likely to die if they were infected, even after controlling for other factors
@SchizBulletin
What is
#recovery
in
#1stepisodepsychosis
? Results from a 10yr study found 31.7% "recover" based on >1yr of psychotic symptom remission + adequate functioning but ~1/5 of healthy controls don't meet this threshold suggesting criteria should be reconsidered
Can we predict who will have persistent symptoms in
#earlypsychosis
? Researchers developed and validated a risk prediction model of symptom non-remission using baseline demographic + clinical variables w/ good discrimination
@samleighton87
@SchizBulletin
A new meta-analysis
@JAMAPsych
by researchers
@KingsIoPPN
presents results from 9,222 individuals at clinical high-risk for
#psychosis
: transition risk plateaus at ~30% at 4-year and the presence of BLIPS poses a higher risk.
A brilliant new
#meta
-analysis in
@SchizRes
included 33,456 participants & examined important moderators of social functioning trajectories in
#psychotic
disorders. Biggest improvements were found over time in those with a duration of illness < 5 yrs.
Is depression intrinsic to
#psychosis
? PRONIA study shows little separation in brain structure and the experience of depression across groups with recent-onset depression and recent-onset psychosis (with+without depression)
@unibirmingham
@SchizBulletin
#SIRS2021
Plenary Session 3: The Identification of Cross-Cultural Causes of Mental Illness and How to Address This in Mental Health Care with Focus on Psychosis with Kwame McKenzie is happening NOW!
@kwame_mckenzie
Congratulations
#SIRS2021
Poster Awardees!
411 posters presented & 28 finalists, w/3 identified as top overall!
@Nature_NPJ
Schizophrenia awarded to
@rob_mccutcheon
Glutamate Connectivity Associations Converge upon the Salience Network in Schizophrenia and Healthy Controls 1/5
Congrats to
@PatMcGorry
and
@orygen_aus
for receiving a large research grant aimed at predicting, treating and preventing the progression of psychotic illnesses such as
#schizophrenia
in at-risk young people.
#SIRSmember
It is World Mental Health Day! We aim to increase the public understanding of those impacted by the diagnosis of
#Schizophrenia
and related disorders. Make a difference by visiting our site and donating here today:
#WorldMentalHealthDay
#SIRS
#MentalHealth
Congratulations Connor Dunleavy on winning the Schizophrenia Research Poster Award for your poster: Brains in a Dish! Utilising Induced Pluripotent Stem Cells (iPSCs) to Investigate Inflammatory Dysfunction in Schizophrenia
#SIRS2022
The
@SIRSGlobal
Impact of the COVID-19 Pandemic on Psychosis webinar is now available on SIRS website for members and non-members. Share the link with our colleagues and watch it now at:
#psychosis
#schizophrenia
#SIRS
Today on the International Day of Women & Girls in Science, we are pleased to announce the upcoming
#WomenInScience
workshop at the
#SIRS2022
Congress. Join us for an important discussion on women representation in academics, research, & neuroscience!
@BettaCdelRe
@MarycannonMary
#SIRS
members & awardees are making an impact on the treatment & support of people with a diagnosis of
#schizophrenia
. Check out our most recent blog post from SIRS 2022 Outstanding Clinical/Community Research Awardee Matcheri Keshavan
@keshavanms
Insomnia in schizophrenia is associated with adverse outcomes. In a meta-analysis of RCTs
@SchizRes
, researchers
@AUG_University
found that clozapine was associated with less
#insomnia
compared to other antipsychotics such as risperidone or olanzapine.
Registration is NOW OPEN for the
#SIRS2022
Congress! The
@SIRSGlobal
2022 Congress will be in a hybrid meeting format allowing in-person attendance in Florence, Italy, or virtual attendance on the
#SIRS
Virtual Meeting Platform.
#schizophrenia
Prepare to be inspired at the
#SIRS2022
Congress. Don’t miss our keynote session with Cecilia McGough & Students with Psychosis. The early registration rate ends 22 February!
@Cecilia_McGough
🔬Study (
@SchizBulletin
) links childhood trauma to altered default-mode network (DMN) connectivity in
#schizophrenia
. DMN connectivity thus reflects a potential mechanism by which early adversity exerts deleterious effects on cognition.
The
#SIRS2021
Congress will kick off shortly with our Career Development Session and The Future of Schizophrenia Research Workshops! Make sure to check your email each morning for daily updates.
Important study examining the role of childhood
#maltreatment
in educational attainment & cognition in first-episode
#psychosis
& a large sample of community controls. Learn about associations b/t childhood neglect, attainment & IQ here →
@SchizBulletin
A recent
@SchizRes
study explored the symptom well-being relationship in
#schizophrenia
. Results revealed those w/ ↑ positive sx were more likely to report ↓ satisfaction & interest in life across time-points while negative sx had no effect on well-being
🔬A polygenic resilience score moderates the genetic risk for
#Schizophrenia
| New study by Hess et al (
@PGCgenetics
) compares high-risk controls, i.e., "resilient" controls to patients with similarly high polygenic risk scores.
@MolPsychiatry
:
Highlighting necessity of adding trauma-focus to early intervention in
#psychosis
. Jie Zhao, Chuan-Yue Wang and others
@Capital
Medical University, Beijing, China, examine efficacy and safety of
#EMDR
in
#CHR
with comorbid
#PTSD
in recent
#RCT
@SchizRes
Join us in congratulating the
@SIRSGlobal
2021 Early Career Awardees! We look forward to seeing the 2021 awardees virtually at the
#SIRS2021
Congress. See the awardees at
🔬Some young people with early psychosis may not require antipsychotic medication to recover. Francey etal
@orygen_aus
@unimelb
found that psychosocial treatment alone was not inferior to psychosocial treatment plus antipsychotic medication
@OUPAcademic
Negative symptoms improve most in the first 6months after baseline in people at
#CHR
and stabilize afterwards as shown by
@_tanyatran
et al. in NAPLS3
@UCalgary
@queensu
. Pattern is found especially in individuals with ↓IQ & ↓functioning
@SchizRes
A validation study of the transdiagnostic individualized risk calculator for prediction of
#schizophrenia
developed in UK using external data from over 2.43M patients in US shows, although suboptimal, decent prognostic accuracy of 0.676.
@KingsIoPPN
Predicting bipolar I, II, and psychotic disorders in youth presenting to early intervention services: A new study
@PsychMedJournal
reveals suicide attempt, poor social function, and early-onset anxiety/depression as notable predictors.
#psychosis