Our latest paper is out in Science Translational Medicine this week. I’m so proud of the Anderson lab’s MD-PhD student
@Oscarreyesgaido
. CaMKAR and this screen are his brainchild 🤩.
@ScienceTM
@RMesubi
@panagis21
I don’t even think there’s a word to encompass that. Exhaustion of the soul, a tiredness much deeper than exhaustion of the body. My father was always quiet when he came home from the hospital and had lost a patient. He was a peds heart surgeon. I think he cried in his car.
@wilsonmj
@ChristosArgyrop
And in 2018 there were fewer than 16,000 US HIV deaths due to advances such as cART. Your 2-3 million number was GLOBAL HIV deaths. A year into the pandemic, we're at 2.2 million COVID-19 deaths and 99 million cases. We didn't forget. Your analysis is flawed.
@realDonaldTrump
The weekly standard lasted a lot longer than many of your failed businesses, but go ahead and be petty. It's not like you're president or something where dignity matters
@CodyGathersMD
I can’t like this tweet because I’m so angry that this happened to you and happens every day to PoC. I love that you felt brave enough to wear that awesome shirt. Thank you.
@panagis21
A legit percentage of yiayias would book a flight to save their beloved grandkids from a life lacking pastitsio (my mom has flown to visit us and then made baklava since mine isn’t up to par 😂) congrats on successfully cooking a dish I find tedious to make!!
@JBsTwoCents
@evelynfbw
@Noly573962
I did wonder this as well. My experience with kids who (without lissencephaly) are awful sleepers is that, if you can manage to switch off nights for care with your husband or see if a night nurse is covered for medically fragile kids even just for 2x/week — you need rest/respite
@JBsTwoCents
This is one of the cruelest aspects of healthcare in our country, stemming from insurance being a for-profit machine whereas it is guaranteed for citizens in most other countries. The WHO ranks the US 37th for healthcare systems. Kids like Mia get screwed by the bureaucracy. Ugh
What a privilege to present our groundbreaking work on mitochondrial CaMKII in regulating cellular energetics after cardiac injury at
@ASPET
’s annual
#ASPET2023
meeting!
@ScottPresler
@realDonaldTrump
Um... all the legal votes were counted. Many were audited, some twice... and Donald Trump is still, as he always has been, a loser.
@osillygirl
@AshleyGWinter
No; they aren’t. This is actually the leading cause of death for women in places lacking adequate obstetric care. Per the WHO:
@SLady1961
@DrTomFrieden
@MaskShelby
Seriously? Even if it provides 3-6 months of immunity, that could quench this wildfire of cases spreading across the country. You should be excited. This is the first hope we've had in ten months.
@jdpereira
My PhD mentor was a postdoc in a Nobel laureate’s lab. Said laureate one day walked into lab and tried to “help” him by tossing out the supernatant fraction of a tube my mentor was holding… when that was the fraction he actually wanted to save for analysis.
#failedhelpattempt
Me, an adult: finally goes to get a department headshot. Adulting so hard.
Also me: sends headshot to my mother as proof of said adulting.
My mother, a doctor’s wife: you didn’t get your coat dry cleaned before your photo did you? It’s wrinkled. You can see the wrinkles.
Me: 🤦🏻♀️
@JBsTwoCents
Oh Joy Beth. Her eyes look GREAT; you had phenomenal surgeons here. It’s going to get better as she heals too. Looking forward to updates on Mia, Now With Binocular Vision (tiny koala superhero theme song here) ☺️
It was a privilege to give Clinical Pharmacology grand rounds here at Johns Hopkins today. What a turnout, and so many great questions from a group of wonderful scientists. Thank you for inviting me to speak to your department.
@Maratosflier
@blekhman
This is a very defeatist, negative message to send early-career PhD investigators. What it brings attention to is that R-level funding also hasn’t kept up with the cost of living (and the costs of actually doing research) — that $250k doesn’t go as far as it did 10y ago
Good mentors make all the difference for fellows and trainees; they guide our growth on the path to independence as scientists. May all of your role models be as awesome as mine have been
@wallyjoe33
and Raj Kishore
Great talk by Temple’s own
@srhouser1
@ISHR_NAS
this morning on new therapies for HFpEF! Can't wait for my mentor
@wallyjoe33
to give a talk on our lab's work for his Research Achievement Award!
It’s hard to be anything but grateful when I look at the strength and love parents like
@JBsTwoCents
have for their beautiful children who have terminal diagnoses. Little Mia inspires me every day.
Help Mia Live Her Best Life with Lissencephaly
It was a privilege to open the Cardiovascular Pharmacology showcase with our lab's exciting work on GRK2 in the heart! Phenomenal talks in this session!
@CindyBVeldhuis
My suggestion: "I know my last name might be difficult for some to pronounce, so Dr. V. is perfectly acceptable too." It politely sets the tone that it isn't OK to minimize your title/status. So sorry that this happened to you!
@IM_Crit_
@curromir
Yes; age is not a contraindication until you don't have enough ECMO (and trained staff) for all patients who may otherwise be treated. It really sucks, but this is where we go when patients refuse vaccines and won't wear masks; triage biases towards patients with best chances.
@kathleen_beeson
@harvardmed
Feels. Here at Hopkins, postdoc fellows are binned into the “student” bucket for a lot of things (because we’re not faculty, but not staff) and have none of the employment benefits and all of the short sticks. I love the people I work with; I hate the way HR treats postdocs.
@susantowerpool
@EM_RESUS
Best analogy my father (a surgeon) gave me before I even thought I wanted to go into medicine: “if I’m the pilot, my OR nurses are my copilots. They’re ground traffic control. They’re the flight tower. I can’t do anything safely or properly without them. They deserve respect.”
Thrilled to celebrate a fundable (and fantastic) score on an R01 from
@MarkRanek
and the
@RanekLab
.
@hopkinsheart
is on 🔥 this year with grant funding awarded to our faculty, fellows and trainees!
No matter how old you are, or how many degrees or papers or grants you have, your Mamà visiting you is better than just about* anything else in the world.
*Maybe if she’d also brought me proper Cuban food from Florida (where she lives) but TSA says No Bueno to carry-on flan 🍮😭
@mi55br00ke
@KelseyObGyn
Likely, more than you have. Including COVID+ ob/gyn patients -- you don't have to be an emergency med physician to care for patients who got Covid-19.
One of my favorite scientists talking about one of my favorite proteins — Eric Olson (
@Transactivator
) discussing how editing of two critical methionines in CaMKII prevent oxidation-driven pathological signaling.
#BCVS23
It was great having our mentor and former physician-in-chief, Mark Anderson, return to JHU for the unveiling of his official portrait (alongside Rick Bennett and Paul Rothman) during the Johns Hopkins Medicine Award and Portrait Presentations.
Cardiology is going to miss the Adamo lab’s awesome student scientist (and my favorite* histology / flow cytometry partner in crime)
@AashikBhalodia
as he leaves to start his PhD soon. Who’s going to count all of our macrophages when you’re gone?
Let’s be real: who else has a stack of science & medical journals in their office waiting for you to find the free time to read them, but instead they just seem to…multiply?
@JBsTwoCents
So glad for an early, fast and accurate diagnosis and a way to control her seizures — prompt ACTH tx vastly improves long-term outcomes in IS. Rooting for you, sweet tough little Mia!! 🎉
@MedFactChecks
@EKing719
No; sorry. You cannot conflate ED with plastics. You literally can't pass boards in one without a two-layer closure. Your white male ego might be hurt, but when plastics is available for a consult, especially for a child's facial laceration -- they're the gold standard.
Happy
#WomenAndGirlsInScience
Day! I’m fortunate to have been raised by two generations of physician-scientists who taught me that I can accomplish anything. As a mother and mentor, I hope that I’m able to pass on this same lesson to the young women in my life.
Hi, I’m Kim. I have OCD and 2 advanced degrees but my toxic trait is that I keep a million browser tabs open for papers. It’s OK folks; they’re organized by project/grant/collaboration. This triggers my mentor every time he sees it. One day I will actually download the PDFs… 😬
@DanWuori
Our eldest was a toddler master of letter swapping, to much hilarity. The movie theater was the “foodie meter” and “hasta luego” (let’s go!) was amazingly “pasta enfuego” (noodles on fire) until she was well older than 3. I love this age.
The next time you think that rebutting journal reviewers’ comments is a pain… I just spent 45 minutes explaining to my child why we cannot have a pet raccoon.
Many thanks to the Heart Failure Society of America's Board of Directors for appointing me to serve as a member of the Research Committee for the 2023-2024 year. Looking forward to a great HFSA 2023 Annual Scientific Meeting this fall!
I’m grateful to my PD advisor
@dkassjhu
for pairing me up with another former Kass fellow
@MarkRanek
as a faculty mentor. I’ve learned so much from these two, and have had a great first year of fellowship here at
@JohnsHopkinsDOM
Such wonderful mentors I have here at Hopkins — thank you
@priyaumapathi
for reminding me of the important things (and now I can point out the LAD on my coat when talking to students!)😂🥰
I just explained to my fourth grader how histones regulate DNA accessibility. Without missing a beat she said, “Like how video cassettes in the olden days wound the tape you weren’t using around spools and only the unwound tape got watched?” Nice analogy, but… “olden days?”🥴
Memories: I’m the 3rd generation Dr. Ferrero, holding the 2nd Dr. Ferrero’s medical school slides, listening to a recording the original Dr. Ferrero left behind. They were both surgeons (heart and gensurg). They taught me.
Some loves are so profound that they change you forever.
@ShawnNeedham2
@aCarnivoreDiet
@DrSiyabMD
Statins are not a magic bullet. They work on one target (HMG-CoA reductase) and HF patients are not a homogeneous group. Your HFrEF pt is not your HFpEF pt +T2D and CAD. The data for statin benefits are strong. But there’s a reason we also rx SGLT2i, ARB blockers, ACEi.
@FIKC37
@christykat1121
@Cleavon_MD
Yes, these people. These irresponsible, selfish people whose awful decisions are taking up much-needed bed space in hospital ICUs and worsening this pandemic. Once more for those in the back: These. People. Got. COVID-19. Because. They. Were. Careless. And. Stupid.
The clouds actually did us a favor and allowed me to grab a photo of the eclipse from Baltimore. That said, I was grateful for the NASA-approved eclipse glasses and the fantastic view from our floor (this shot was taken just outside
@dkassjhu
’s office)
Sleep regressions are the worst. Especially when your infant is more or less a toddler and can now talk their way out of bedtime, argue with you, and wake you up at all hours to have wacky conversations. I don’t even know what day it is anymore. 🫨
@HillaryClinton
@CAPAction
❤ you were the president many of us wanted. I'm sorry that you had to watch our beloved country burn these past four years. Thank you for everything you've done for us.
Thrilled to be attending (and presenting at)
#ASPET2023
in St. Louis, and proud to be a former trainee of
@wallyjoe33
’s lab as he is awarded the Julius Axelrod Prize in Pharmacology
Fun fact about me: I started playing ice hockey in grad school years ago, and I still play. I actually began skating at men’s beer leagues before getting into hockey clinics. I’ve broken bones in three limbs on the ice, including my pipette hand in 2020 😒. I’m also 5’1”.
Patients with evidence of microplastics and nanoplastics in carotid artery plaque, as compared with patients without, had a greater risk of adverse cardiovascular events at 34 months of follow-up. Read the full article:
The $64 million dollar question being… is there really a best animal model for HFpEF? I’m starting to think, no; it’s truly dependent on what readout/symptom set you are interested in and studying.
When you’re standing next to an older male colleague who gets introduced by a third party as “Dr. _____” but you (also “Dr. _____”) are then introduced… by your first name* and not your title.
*I’m not big into titles, prefer just using my name, but I don’t like blatant sexism.
Great seminar by
@MiaoCuiUTSW
today at Temple Med's Center for Translational Medicine. Dr. Cui shares her exciting work on resolving cardiac regeneration at single-cell resolution. Always a delight to see the research coming out of
@lab_olson
at UTSW!
The toughest and yet most fulfilling role I’ve had to live up to is “Mom.” Thankfully I have the best mother in the world to look up to. May you have as much love (as mothers and for your mothers) as I’ve been blessed with. Note: I broke two toes right after this photo was taken.
Great talk about the role of GRK2 in cardiac-adipose crosstalk from Koch lab postdoc
@stephkereliuk
- as
@wallyjoe33
reminds us, GRKs are “keys” to cardiac function!
@drpillado
Long enough to A) perform an emergency cricothyroidotomy, or to B) kick the shins of people who feel the need to critique our heel height at conferences. I wore red stilettos to the last conference I presented at. People remembered my research ...and everyone loved my shoes.
@aCarnivoreDiet
@DrSiyabMD
Um,no. Reduction of LDL cholesterol with a statin reduces the risk of major vascular events, largely irrespective of age, sex, baseline LDL cholesterol or previous vascular disease, and of vascular and all-cause mortality. Source: The Lancet (+ most MDs)
Courtesy my co-fellow
@CharlieCohenPhD
, I bring you the perfect ratio of chocolate to biscuit: the TimTam Double Coat. Enough to dunk in your coffee and throw it over a dingo. Or macrophage. Not an endorsement for a
#hearthealthydiet
@DrHelenECollin1
gave a great talk at EB2022 this morning! Hypertrophic changes during pregnancy are highly important in clinical cardiology and should be discussed more!
How to tell your toddler has some OCD tendencies (if the rows of evenly-spaced, unidirectional fish spotlessly grouped by color wasn’t a giveaway — it’s the one in the upper right)
Worst grant writing buddy ever… He is a terrible writer, barks at the lab staff and doesn’t share his resources. Good thing he’s a loyal colleague.
#dachshundsofmedtwitter
I disagree; in-person communication is crucial. Also, a hard side eye to any PI claiming to be too busy to meet w/ trainees. My mentors have been chairs, directors and deans. They have always made time for their trainees. Nobody is that busy (and if you are, don’t take trainees)
Not sure who is giving this guidance, but PhD students: we don't need to meet to discuss whether or not I should be on your thesis committee. Just send a description of what you do and why I might be helpful. I can decide based on that.
@AmeetRKini
@AshleyGWinter
Not my specialty either but that was my first thought — ITP (immune thrombocytopenic purpura).
@AshleyGWinter
you look like one of our NEJM clinical challenge images! Poor thing; keep us updated.
Having demonstrated his prowess as a killer by removing the squeaker from his stuffed animal, the mighty hunter basks by the fire we made just for him. Or… something.
#drdachsund
#dogsofmedtwitter
Dr. Leslie Leinwand pointed out in her award talk this morning
@ISHR_NAS
that 90% of PCPs don't know that CVD kills more women than the next 7 causes of death combined. Addressing this is crucial for improving pt care for CVD. Great work by a great investigator!
Came across a wonderful little tribute in my neighboring department. LKSOM's pathology chair (Yuri Persidsky, MD, PhD) is originally from Kiev. Thousands of tiny gestures of support and solidarity in truly awful times for Ukraine 🇺🇦 ❤
@DrSandman11
@MarianHolling
I am guilty of this. Also a common tell is any mention of pulling your info from EPIC/Cerner esp wrt labs before encounter. Or the tiny things like writing “s/p” on new pt hx forms have outed me. That said, it does streamline the H&P when your patient knows what’s pertinent.
Oldest kid is home sick after inheriting the youngest’s recent URI. She’s watching Kung Fu Panda 3 and texts me a scene she finds profound in the film. The quote? “If you only do what you can do, you'll never be better than what you are.” -Shifu.
I am impressed by my child. ❤️
PSA: there is no reason for measles vaccination rates to be dropping the way they have in recent years. The measles vaccine has been available and safe for over 60 years, costs less than $1USD per child, and has prevented an estimated 56 million pediatric deaths since 2020. 1/🧵
@JBsTwoCents
I asked
@WhiteCoatOnFire
this morning how often he thinks about the Roman empire. Without missing a beat between sips of coffee, he quipped “all the time.”
Our colleague
@priyaumapathi
presenting her work on the role of O-GlcNAc in driving heart failure, as winner of the basic science faculty research award at
#HopkinsResearchRetreat
Got my first dose of the Pfizer SARS-CoV-2 vaccine this morning. Seeing this entire process unfold (during a pandemic!) from bench to bedside has been humbling. I am fortunate and proud to be part of the
@templemedschool
community