This randomized clinical trial assesses the ability of selenium and vitamin E to prevent non–muscle-invasive bladder cancer (NMIBC) recurrence and progression in patients with newly diagnosed disease.

AbstractIntroduction:As overall survival in prostate cancer increases due to advances in early detection and management, there is a growing need to understand the long-term morbidity associated with...

When the avocado was first discovered by the Aztecs, they gave it a name that translates to "testicle" — likely because of the texture, shape, and size of the fruit, as well as the way it grows in...

Between 1999 and 2009 in the United Kingdom, 82,429 men between 50 and 69 years of age received a prostate-specific antigen (PSA) test. Localized prostate cancer was diagnosed in 2664 men. Of these...

Despite the widespread use of robotic surgery and advances in surgical technique and patient postoperative management, we did not observe an improvement in the rate of post-radical prostatectomy (RP)...

Our findings suggest the 2008 policy change shifting clean intermittent catheterization coverage from catheter reuse to single-use did not decrease hospitalizations for urinary tract infection or...

PURPOSEPrevious comparative effectiveness studies have not demonstrated a benefit of proton beam therapy (PBT) compared with intensity-modulated radiation therapy (IMRT) for prostate cancer. An...

Hematuria comes in two main varieties: gross and microscopic. A wide range of ailments can lead to hematuria, and the central task is to rule out life-threatening disease, mainly cancer. This artic...

In patients with regular baseline function and two kidneys, we found no evidence of differences in functional outcomes for on- vs off-clamp RAPN.

Despite the innovations made to enhance smarter screening and conservative management for low-grade prostate cancer, overdiagnosis, and overtreatment remains a major health care problem. Driven by...

Testicular germ cell tumor (GCT) is the most common solid tumor in adolescent and young adult men. Progress in the management of GCT has been made in the last 50 years, with a substantial improveme...

Urologists and radiation oncologists are more likely to differ than agree in their treatment recommendations for the same patients with clinically localized prostate cancer and more likely to favor...

DCE-MRI performed better than T2-weighted imaging and DWI for estimation of index PCa volume and therefore can be preferred over these other two sequences for volume estimation.

Abstract. Deep learning (DL)–based algorithms to determine prostate cancer (PCa) Grade Group (GG) on biopsy slides have not been validated by comparison to

PURPOSEIn a professional setting, the introduction of female speakers without their professional title may have an impact on the public’s perception of the female speaker. We examined how professio...

In a large U.S. screening trial, the addition of percent free PSA to total PSA in men with baseline PSA ≥2 ng/mL improved prediction of clinically significant prostate cancer and fatal prostate...

The initial report on finasteride for prevention of prostate cancer documented a reduction in prostate cancers but a paradoxical increase in high-grade tumors. Prolonged follow-up and surveillance ...

A man’s baseline prostate-specific antigen level can guide decisions on the repeat screening interval, as demonstrated using 16-yr follow-up data from the ERSPC trial.

Patients undergoing evaluation for solid organ transplantation (SOT) often have a history of malignancy. Although the cancer has been treated in these patients, the benefits of transplantation need...

Cancer survival and overall survival in patients with Bosniak IIF to IV renal cysts was high with only 1 cancer specific death. No cancer deaths were recorded in patients who did not undergo interv...

In this randomized trial, conducted between 1989 and 2022 to compare radical prostatectomy with watchful waiting, radical prostatectomy led to a 48% lower risk of death from prostate cancer and to ...

Hematuria following PPRT is common, especially among men with medication allergies and those on anticoagulation/antiplatelet therapy; however, PPRT-related hematuria is typically self-limited....

Low-Grade Prostate Cancer: Time to Stop Calling It Cancer

Low-grade prostate cancer should still be labelled cancer

Our study confirms that small testicular masses are often benign and do not always require radical orchiectomy. Preoperative ultrasound can assess lesion size and the smaller the nodule, the less...

A new clinic focuses on patients left grappling with the aftermath of treatment in ways that are rarely appreciated by doctors.

Approximately 1 in 8 patients with a renal mass > 4 cm harbored benign or low risk indolent potential lesions and were associated with younger age. As such, patients with large renal masses for whom...

The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management...

This systematic review and meta-analysis evaluates biopsy decision-making strategies for avoiding unnecessary biopsies and minimizing risk of missing clinically significant prostate cancer.

We have previously shown how mismanagement of testicular cancer results in a higher rate of disease relapse. In this study, we emphasize how the lack of adherence to standard treatment guidelines can...