Director Medical Oncology & Palliative Care Penn Med Princeton Health
Assistant Professor
@PennMedicine
@PC3Innovation
GeriOnc Co-Lead Penn Medicine CSL
1/6 Our JCO piece
@guptaarjun90
on the need to improve communication training in
#medonc
fellowship. Every day oncologists deliver bad news. The words we choose impact pts & caregivers. Our training does not reflect the gravity of this
@tmprowell
@AAHPM
Summary thoughts from my Grand Rounds today on the role of Palliative Care in Cancer:
-We need to prioritize the patient experience. There is more to life than scans & death
-We cannot eliminate suffering, but we can anticipate it, name it, and try to alleviate it
Title says it all: "Is everything we eat associated with cancer?"
Take home point: nutritional epi evidence is weak. Cancer patients go through enough; let them enjoy food without feeling guilty or anxious
HT
@VPrasadMDMPH
@adamcifu
Medical Reversals
In the
@JCO_ASCO
‼️‼️,
@ravi_b_parikh
& I make the case for 🎯"Precision Palliative Care" 🎯as a pragmatic solution for a care delivery problem
A 🧵
Article
A sad reflection as I walked through the exhibition hall of
@ASCO
Pictured here are humble booths (compared to Pharma exhibits)
Yet, these advocacy booths do so much for patients. Often, they literally save a person or families life. I applaud
@ASCO
for sponsoring this
New ASCO Guideline on Palliative Care for Patients with Cancer
1. Early referral to SPECIALIZED PC leads to improved QOL, mood, higher likelihood of documenting EOL preferences
2. PC teams are fundamentally interdisciplinary
3. PC benefits caregivers
While amazed at scientific advances
@ASCO
, returning to clinic was a humbling reminder that pts still suffer from:
--inability to afford care
--transportation needs
--polypharmacy
--unaddressed pain
--navigation
--poor communication
We need to raise the ceiling AND the floor
We forget median OS for EGFR mutated lung cancer is ~3 years, >40% with grade III adverse events
I worry about the culture in oncology where these patients are seen every 3 months & we ignore their existential/emotional/symptom needs
cc:
@JackWestMD
Lessons from Encanto for Onc/PC teams:
-no home (institution) is perfect
-be emotionally authentic
-talk about Bruno (fears/hurt)
-can't ignore painful experiences
-we fail when we try to b superhuman
-Find strength in community
*Death* can be transformative
cc:
@tmprowell
So glad to see this piece making waves again on Twitter
I was beaming with pride & thankful for great mentorship to see our paper highlighted in the
@ASCO
#ASCO24
@ASCOPres
address
‼️‼️All residents applying to
#hemeonc
fellowship
Consider applying to novel integrated pall-heme-onc track at Mt. Sinai, Fox Chase, Ohio State or Pitt
Hear what experts in the field have to say, including future
@ASCO
President Dr. Lynn Schuchter
1st generation kids know the struggle: stigma, cultural barriers, confusion, guilt, seeing isolation & constant hustle in parents
American dream is seeing your name decades later below
@FLOTUS
(thanks for your inspiring message!)
@PennCancer
Amazing advances at
#ASCO22
. Small reflection:
Easy for trainees & faculty to feel inadequate or that you don’t belong. Yet far from true.
Research takes a village, teams, opportunity, & sponsorship. Hard work yes, but often dependent on being in the right place at right time
In oncology education, we do not emphasize enough the importance of encouraging patients to live their best life
Too often, people are under the impression that they must isolate from their children & grandchildren during treatment, when it is clear that is who they live for
Recently, I lost a pt I really liked. Surprisingly, during a brief 15 min bereavement call, I discovered more about their life than I had in 2 yrs.
Bereavement is likely not in the curricula for oncology fellows this July, maybe not at all over 3 years.
It should be.
@NEJM
clinical practice review on hypercalcemia
3 times noted that cancer-associated hypercalcemia portends a poor prognosis
0 times recommended to include "serious illness communication" as part of the intervention
culture change starts here...
#supportiveoncologypearls
Day 2 of pall care fellowship. Lots of focus on language
We de-escalate interventions, not care
Care for the patient is always there
Our patient page in
@JAMAInternalMed
"How Can Palliative Care Help Me"
Palliative Care is SPECIALIZED Care!
It improves people's lives & helps caregivers
PC is based on need, not prognosis
PC is appropriate at any age & is based on need, not prognosis
Great visual of why late referrals to PC dilute its efficacy. Takes TIME to develop rapport, plan for the future, cope.
We are always quick to treat the cancer. We need similar urgency to address ALL domains that impact persons/caregivers, too.
After attending
@CareMcgill
conference, a few reflections as a medical oncologist:
1. there is lots of $$$/support behind new technology in cancer. Liquid biopsies, NGS, etc. Reality: few pts benefit. Those who do, rarely a cure.
2. there is limited enthusiasm/support for....
Thank you to all of the trailblazers in
#pallonc
who made a situation like this even possible
35+ people together on
@ASCO
communities of practice call on how to integrate a career in onc & pall care
Excited to see the future move oncology care forward!
Starting
#ASCO24
reading a moving piece by
@guptaarjun90
in
@ASCO
connection
Mrs. Thompkins, wanted a pear while admitted, but was unable to due neutopenic diet
He gets her a pear. Proceeds to investigate the evidence behind neutropenic diets (there is none), leading to
I’m often struck by how vivid the memories of a loved ones final days can be for surviving family. Even decades later.
The importance of end of life & bereavement care reaches beyond any quality metric. It’s our moral obligation to one another
@edubru
@guptaarjun90
@JasAWebb
Congrats to the investigators for amazing work BUT...
Anyone frustrated that STILL - we are asking for data to show that integration of palliative care, serious illness conversations and geriatric assessments are good for patients?
THIS SHOULD BE SOC
#ASCO20
#GeriOnc
#pallonc
The 5 A's of Access. Important concept in health equity
-in cancer medicine, there are major gaps
-care & caregiving is unaffordable
-clinical trials too "centralized" at specialty centers
-overburdened providers w/o incentives to change
-underprioritize care delivery research
Proud of
@guptaarjun90
who took this concept as his original idea & ignited a movement in oncology
Using a Real-Time Location System, his team demonstrates even the simplest of clinic appts can take up hours of patients' time
Behavioral economics can be used to improve hospice utilization for patients w/cancer
Lessons learned & thoughts from our randomized trial below
Thank you
@ConquerCancerFd
@ASCO
for funding this work
A fantastic piece I missed when published
@ASCO
@rochgerionc
#geriOnc
Understanding treatment tolerability in older adults
It has too much depth to fit in a tweetorial; this is a must read
In lockstep with the
@ASCO
Presidential Theme
@ASCOPres
- Palliative Care is on the stage as a PLENARY at this year's Annual Meeting
This kind of research matters - has reach, clinical practice, and policy implications
I often think of this article
@AlexSmithMD
when patients w/cancer are offered the dangling carrot: "you'd qualify for more chemo, if you can get stronger"
What follows is a distressing cycle b/w hospital and rehab. It is costly and demanding on families
Televisit today:
-patient on 3rd line therapy of metastatic solid tumor
-discussed supportive care needs & adjusted meds
-WHILE patient was poolside on vacation, and I met her family/friends
THAT is leveraging technology to meet patient needs!
#QOl
#pallonc
@guptaarjun90
Open invitation to all residents/fellows/faculty/patient advocates interested in joining
@ASCO
PALLIATIVE CARE Communities of Practice
We meet monthly to discuss many topics at the intersection of oncology/palliative care
Signup is here:
One of the hardest questions asked in the oncology office involves prognosis: "doc, how much time do we have?"
I've stumbled & fumbled - I'm sure many of us have too. A thoughtful approach, shared by
@peterbachmd
cc:
@guptaarjun90
@fischmd
For oncologists who are either dual-trained in palliative care - or - focus their research on palliative care delivery consider joining the
@ASCO
PC Communities of Practice
A group of like-minded colleagues offering peer-mentorship & collaboration
The wisest presentation at the
#ecancerchoosingwisely
has just been made by the youngest man here
@guptaarjun90
. Watch out world, this young oncologist is going to be a superstar of oncology very soon. Proud of him! 👏👏👏
The impact of pall care dose intensity on outcomes for patients with cancer - Our Editorial
@guptaarjun90
now available in
@TOncologist
tweetorial below
Dr. Temel presents stepped PC trial, a practice changing paradigm for integration of palliative care in cancer
#ASCO24
This sets the foundation for PC intensity (dose) based on need
our field suffers a cognitive dissonance when we push for things that help <5% of people - yet-
we do little to improve geriatric assessment, primary palliative care skills, specialty PC access, interventions for dyspnea/pain/cachexia, support to families at home, access to SOC
In honor of World Hospice & Palliative Care Day,
@ASCO
shares an important message on "Making Palliative Care a Part of Your Oncology Practice"
We discuss:
-benefits of early PC
-current & ongoing research
-important of multidisciplinary team
-ways
58! trainees in the
@ASCO
information session: Combined Fellowship Training Programs in Hematology/Oncology and Hospice/Palliative Care
The future is bright!
This
@guptaarjun90
piece shud be req reading in onc training. So much here to reflect on
Will we encourage academic centers to model time tox considerations? Will we incentivize care close to home or at home?
love to see someone reimagining what we do
Inspiring stardom by
@DrHKantarjian
from Beirut to Chair of Leukemia
@MDAndersonNews
Immigrants do it well, deserve opportunity in our US health system & improve patient care. They are a natural answer to our physician shortage
Olanzapine (low dose 5mg) added to traditional anti-emetics improved cisplatin induced n/v
@guptaarjun90
@edubru
Have seen patients complain of somnolence from the previously studied 10mg dose - so nice pragmatic information for patient care
This is the 1st time I read through the entire
#GeriOnc
ASCO guideline... wow it is good
Thank you
@rochgerionc
@WilliamDale_MD
@aakonc
et al for this work
and
@myCARG
clinical implementation core for feedback prior to our GeriOnc clinic pilot...
The ability to die at home takes a village
25% of people at EOL need a full-time job’s worth of unpaid help. In decedents w/dementia, ~50% received >40 hours of caregiver hours
Policy changes needed
CC:
@guptaarjun90
@WilliamDale_MD
@rabrazzak
We see death everyday in oncology. An unmet need is education on complicated grief & bereavement - and resources to address family needs.
Well documented risks of depression, anxiety, self-harm and loss of function for >10 years after loss of a loved one in susceptible persons
So proud of
@guptaarjun90
senior author
@JCOOP_ASCO
paper while mentoring rising 🌟
@vrpatel97
. PS! there is a NOVEL finding
Question: Can we characterize "time toxicity" for pts w/cancer
Yes! 1 in 4 days alive were in health care contact
Despite all the talk on financial toxicity, there is minimal effort to explore the business & finance aspects of cancer care. If our field is filled with clinicians "just taking care of patients" or "doing their research" nothing will ever change
No one warns you in medical school the daily sorrow experienced when your patients either can’t receive standard of care or accrue debt for getting sick
A shame for a country of great wealth & resources
Finished my last inpatient solid tumor rotation as a first year fellow. The greatest lesson so far- pathophysiology, trial data, genomics are always second to an individuals performance status and social history
@guptaarjun90
@oncology_bg
For all the new onc fellows out there - a heartfelt read - and a story I read time and time again
Pain, suffering, caregiving, hope, joy and love - are experienced by individual persons
#OncologyCare
Can Community Health Workers increase palliative care use for African American Patients with Cancer?
Yes, potentially. Our work
@FabianJohnston
#awesomementor
published in
@ASCO_pubs
A 🧵
On this Labor Day, would like to thank the physician residents/fellows & patient caregivers. Two underappreciated communities that keep our health system afloat
Touching moment as Dr. Tom Smith is asked to reflect how his personal experience w/cancer impacts his care for patients
Dr. Smith: "Ask the patient how are you coping, and then turn to the caregiver and ask, How are you coping."
#SuppOnc19
#Caregivers
@ASCO
@AAHPM
#pallonc
Wanted to highlight a key RCT fpresented by
@efratdotan
#ASCO24
. The GIANT TRIAL - first older adult focused treatment trial in pancreas cancer
It highlights the importance of GERIONC trials and several key principles of oncology
As oncologists, if we had a therapy that improved QOL, symptoms, mood, coping and caregiver distress, & has never been shown to cause harm…
We’d make sure we have available for all of our patients
That’s what integration of palliative care offers our patients
Death, grief, & bereavement is a part of cancer. Today, we reflect back & honor those who died under our care. What a privilege it is to care
For those who have never participated in a service of remembrance, I encourage you to join your cancer centers program if it exists.
If
New editorial led by
@KathrynDeCarli
& ft
@ASCO
Jamie Von Roenn! We explore what the future may look like for dual-trained physicians in oncology & palliative care as this is now a growing option for trainees
@PC3Innovation
@PennPalliative
Will be sharing all things palliative/supportive care and GeriOnc
#ASCO24
Starting with sharing two publications from the
@ASCO
E-Book
1. PC Communities of Practice -
In this piece,
@MazieTsangMD
I and colleagues share our experience as members
Announcing the 2024 ASCO Annual Meeting Featured Voices! Follow along for a range of expert insights & join the discussion using the official hashtag:
#ASCO24
⤵️
@guptaarjun90
at it again!
We all scoff at the idea of Financial Toxicity & wonder what we can do to mitigate. Ever wonder the implications of patient parking? Take a read...
@tmprowell
@yzafar
@fumikochino
Majority of med-specialty boards do not have an official lactation exam accommodation policy
~25% of lactating test-takers used test time to express milk & 42% experienced breast engorgement from inadequate/delayed milk expression
cc:
@tmprowell
We investigated EOL characteristics associated with short hospice length of stay (<3 days) of our patients enrolled in phase I cancer trials
@guptaarjun90
Risk factors:
-older age
-referral from outside institution
-not being seen by palliative care
Really excited to work with community agents of change & policy to improve access to palliative care for patients with serious illness across the state of NJ
#GOCCNJ
is pleased to announce the appointment of
@ramsedhom
to its Board of Directors. Dr. Sedhom's hands-on experience & insight into delivering care for patients w/serious illness will strengthen our breadth of talent making him a great asset to GOCCNJ & NJ.
@PrincetonHealth
Lessons from
@ASCO
Pall Care Communities of Practice chat w/
@edubru
"How to Build a Clinical Palliative Care Program"
1. Name change to Supportive Care increases referrals
Major credit to
@ASCO
@ASCOPres
@jrgralow
for communicating the importance of Palliative Care integration in Cancer
Looking forward to this webinar on World Palliative Care Day, October 14th.
This work needs more attention!
Older adults are underrepresented in clinical trials & receive treatment w/limited data on tolerability
Mentee of
@rochgerionc
shows primary dose reduction improves treatment tolerability among older adults w/ advanced cancer & age-related
It's about that time of year when graduating fellows are considering new jobs. Here is a blog post I wrote with
@ASCO
Connection. Hope it is helpful to some considering a non-traditional path
Published 25 years ago; still relevant. Trainees witness this existential slap when patients are hospitalized. It's hard
I found this quote thoughtful:
"It is good to glance at the sun [death], and be aware of its existence, but staring at it will make you blind."
Thank u
@ASCO
for an opportunity to share the value of dual-training in medical oncology / palliative care
Much thnxs to
@guptaarjun90
for nudging this career path & to mentors
@arifkamalmd
, Jamie Von Roenn, & Tom Smith
Yes…AND there is one other intervention with multiple positive RCTs demonstrating benefit for patients & caregivers, improves quality of life, coping, prognostic understanding, costs of care, satisfaction, & survival
Not mentioned once… Early Palliative Care
The face of lung cancer has changed, & our care for young adults needs to catch up!
A holistic approach is crucial:
- ⚠️ Risk factors
- 🧬 Genetic predisposition
- 🔬 Clinical/molecular profiling
- ❤️ Sexuality/fertility
- 🧠 Psychosocial/QoL outcomes
#ASCO24
@ASCO
@OncoAlert
@colleenmfarrell
Most of internal medicine (chronic disease care) is palliative care
Minimal cures, alleviating suffering, improving quality of life. But we aren’t taught within that framework and that’s a loss for patients and clinicians IMO
Physicians are resilient - don't let administrators make you feel otherwise. Medicine has MAJOR systems problems
We need to do better; those in leadership need to support their peers/juniors. When looking for a job, DONT DISCOUNT the importance of work culture
Dr
@IshwariaMD
discusses the major impacts and repercussions of burnout, not just for
#pallonc
and
#supponc
professionals but for all health care providers for
@ASCO
Community of Practice. Not too late to join, DM me for a link.
Among all the debates of PFS vs. OS, few call out this fact: neither capture a common shared value of older adults w/cancer — functional independence. Per AARP: 81% of older individuals prioritize staying at home. Time to reconsider “value”
@rochgerionc
@WilliamDale_MD
So proud of my colleague and friend
@Tara_KaufmannMD
for this EXCELLENT perspective on how structured ePRO monitoring can allow pathways to tailored supportive care services
This is the blueprint for "precision" person centered care
cc:
@fischmd
Death notifications of patients to me are always an opportunity to reflect on
1) gaps in care for pts w/cancer
2) continued suffering experienced by caregivers
3) limited educational focus on palliative care principles
& most importantly - the significance/purpose of our work
Recently, a psychologist caring for a pt of mine & their distressed caregiver visited the bereaved family the morning after death from cancer
No RVUs, no dashboard to capture quality of care provided. These are the things administrators will never understand or $$ support
One of my fav abstracts
#ASCO24
by FELLOW
@MaryBoulanger4
qualitative study exploring communication gaps when starting immunotherapy for incurable cancers. Important work we can all learn from. Mentored by
@lpetrillz
(who has done other great work in