Jake P. Mann @jakepmann Twitter profile

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Jake P. Mann

10 months

How to get started in research TL;DR: - Know what you want to get out of it - Email supervisors who you are interested working with - Take advice to get funding for dedicated research time A big 🧵...

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Jake P. Mann

@jakepmann

11 months

I love my job. I know there is lots to be downhearted about as a trainee (or consultant) in the UK at the moment, yet I want to pipe up that there are jobs out there that are brilliant. I get to work in an exciting field with a committed team and have lots of autonomy. There’s

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Jake P. Mann

@jakepmann

9 months

I like nights. The day before the first shift feels like free time - whatever I get done is a bonus. Getting into bed during the day is a treat. If there's nothing happening at 4am, it is the best kind of break - there is genuinely nothing to do. Whereas there is always stuff to

Keith Siau

@drkeithsiau

10 months

Ok, what’s your unpopular opinion in medicine that will get you in this position?

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Jake P. Mann

@jakepmann

2 years

Really excited to say that I’ve been offered a post as NIHR Academic Clinical Lecturer @unibirmingham @unibirm_MDS to start later this year. I’ll continue to train in hepatology @BWC_NHS whilst doing research with @BirminghamLiver among others

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Jake P. Mann

@jakepmann

2 years

@thivyamk I graduated in 2012 (from Birmingham) so they're a bit old, but here's everything I have electronically: 👍👍👍

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Jake P. Mann

@jakepmann

11 months

As several people have highlighted, my research post is a crucial factor in why I enjoy work. This is why I keep banging on about how great these careers are. The 𝗨𝗞 𝗻𝗲𝗲𝗱𝘀 𝗺𝗼𝗿𝗲 𝗰𝗹𝗶𝗻𝗶𝗰𝗶𝗮𝗻-𝘀𝗰𝗶𝗲𝗻𝘁𝗶𝘀𝘁𝘀, 𝗲𝘀𝗽𝗲𝗰𝗶𝗮𝗹𝗹𝘆 𝗶𝗻 𝗽𝗮𝗲𝗱𝗶𝗮𝘁𝗿𝗶𝗰𝘀.

Jake P. Mann

@jakepmann

11 months

I love my job. I know there is lots to be downhearted about as a trainee (or consultant) in the UK at the moment, yet I want to pipe up that there are jobs out there that are brilliant. I get to work in an exciting field with a committed team and have lots of autonomy. There’s

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Jake P. Mann

@jakepmann

2 years

Sharing all my notes from Medschool (clinical years), plus from MRCPCH and MRCP. #medtwitter 👇

Jake P. Mann

@jakepmann

2 years

@thivyamk I graduated in 2012 (from Birmingham) so they're a bit old, but here's everything I have electronically: 👍👍👍

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Jake P. Mann

@jakepmann

9 months

I've got 'better' at ePortfolio as I approach the end of training. I realise its extremely boring, but it is necessary. I used allow my resentment for the process mean that I didn't do anything until the last minute. However, with crunch ARCPs looming, I have aimed to do one

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Jake P. Mann

@jakepmann

1 year

The main paper from my PhD is out! We found that a very specific mutation in a mitochondrial fusion protein (Mfn2) causes adipocytes to become stressed, which lowers their leptin release. Full paper: My (lay) summary: 🧵...

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Jake P. Mann

@jakepmann

6 years

When the speaker puts up a good flow diagram... #ILC2018 @EASLnews

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Jake P. Mann

@jakepmann

11 months

✍️How I approached ‘white space questions’ in ACF applications: 1. For “Describe your suitability for…”-type questions: state three traits/characteristics that would describe the ideal candidate (e.g. ‘communication skills’, ‘breadth of knowledge’, ‘team player’). Then give a

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Jake P. Mann

@jakepmann

4 years

Some good news: after my PhD I'll be moving to @Bham_Childrens to train in hepatology. After talking about it for quite some time I'm looking forward to actually doing the clinical job, as well as joining the @WMPaeds team. #GRID @BSPGHAN

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Jake P. Mann

@jakepmann

1 year

Never allow “brilliant assholes” into your department. They do exist. And will infect the culture of the team.

Simon Fleming 🛠

@OrthopodReg

1 year

Can you be a good/great trainer *and* a bully? #medtwitter #MedEd

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Jake P. Mann

@jakepmann

4 years

I'm thrilled that our meta-analysis of animal models of NAFLD is going to be coming out in @eLife We think our results are important for all involved in pre-clinical studies of NAFLD. Tweetorial summary to come...

Weight loss, insulin resistance, and study design confound results in a meta-analysis of animal...

Animal studies of fatty liver disease over-estimate the benefit of drugs due to publication bias and are confounded by off-target weight loss, illustrating the challenge of successful translational...

elifesciences.org

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Jake P. Mann

@jakepmann

11 months

After many extra lists…

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Jake P. Mann

@jakepmann

11 months

So, if you are a trainee/student/consultant wondering whether there is anyone left in the NHS who feels positive about their job: yes, yes there’s certainly at least one of us.

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Jake P. Mann

@jakepmann

9 months

Back to clinical full-time for the next 3 months. Last 3 months on research have let me send off (many!) small grant applications. I have found the process of writing useful for clarifying ideas about exactly what I want to do. Data and samples coming in just as I go back to

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Jake P. Mann

@jakepmann

10 months

The most common feedback I gave at yesterday's SFP interview practice: [drop me a message/email if you want a link to the recording and the questions we used] - Give specific/concrete examples of your experience even when answering a relatively general question. E.g. "What

Jake P. Mann

@jakepmann

10 months

SFP interview practice session: Monday 13th November 2000-2200 via Microsoft Teams Mock interviews for specialised (academic) foundation programme. We will run it as an open session so everyone listens to each other. The first 9 signing up will be asked questions and then

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Jake P. Mann

@jakepmann

2 years

Officially begin as a NIHR academic clinical lecturer today. Starting on a clinical block and with thinking/planning research behind the scenes. Looking forward to getting back to the liver unit.

Jake P. Mann

@jakepmann

2 years

For clinical-academics: What is one thing you wish you had done differently when starting your first mixed clinical-research post? New job starts soon…

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Jake P. Mann

@jakepmann

10 months

Thinking of applying for GRID? (paediatric sub-speciality training). Here are five things to consider: 1. GRID vs. SPIN 2. How many jobs to rank 3. Get rid of perceived barriers 4. Specialty-specific examples 5. Distinguish audit/QIP/research 1. Be crystal clear about the

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Jake P. Mann

@jakepmann

11 months

I am also aware of my privilege as a white, cis-male, native English speaker from a middle-class family. This has certainly influenced my career trajectory. Individuals from different backgrounds may have an alternative outlook on prospects on working as a NHS clinician.

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Jake P. Mann

@jakepmann

2 years

Takeaways from the AASLD-EASL Masterclass 👇 - You need to be persistent in grants/papers/discoveries - Tell the story of your research - Friends made through collaboration can last a lifetime Thanks to all the organisers.

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Jake P. Mann

@jakepmann

11 months

Yes, pay should be higher, there’s well described concerns about the roles of non-medical graduates, we get messed around on rotas, the workload is heavy, we do unpaid extra hours, waiting lists continue to climb, we aren’t paid for study leave/courses, the job application system

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Jake P. Mann

@jakepmann

7 years

The world’s kindest delivery-person from @UPS just stacked 600kg of books in 51 boxes in my shed today. Totally above and beyond. @UPSHelp can you help me find them so I can say thank you?

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Jake P. Mann

@jakepmann

11 months

I was talking to a ST3-4 trainee this week about sub-specialisation. They were leaning away from sub-specialities with high 'competition'* for consultant jobs. I suggested not to worry about competition, if you can become 𝘁𝗿𝘂𝗹𝘆 𝗲𝘅𝗰𝗲𝗹𝗹𝗲𝗻𝘁 in your niche. 🧵

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Jake P. Mann

@jakepmann

10 months

I’m chuffed to have finished 6th in the Hardwolds 80miler yesterday. I feel like I can definitely call myself an ultrarunner now. Absolutely perfect conditions and brilliant organisation by the lovely @HardmoorsUltras team. Would highly recommend.

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Jake P. Mann

@jakepmann

11 months

Yet, on balance, I still choose this job. This decision may change as situations evolve.

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Jake P. Mann

@jakepmann

2 years

Just three weeks until I start my 50% research / 50% clinical post. Exciting times. The work begins soon.

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Jake P. Mann

@jakepmann

2 years

@Medic_Russell

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Jake P. Mann

@jakepmann

4 years

🚨 New pre-print following on from our last analysis of rodent models of NAFLD. We analysed over 4,500 papers and found 3,920 unique model designs. [Quite a lot more than we had anticipated when starting.] Full database of models free available.

A systematic analysis of rodent models implicates adipogenesis and innate immunity in pathogenesis...

Animal models of human disease are a key component of translational research and yet there is often no consensus on which model is optimal for a particular disease. Here, we generated a database of...

www.biorxiv.org

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Jake P. Mann

@jakepmann

1 year

🎉 Celebrate! 🥳 Your regular reminder that: You are allowed (/encouraged) to celebrate ‘small’ papers / ‘just’ a poster / ‘only’ passing ARCP. Take the opportunity to celebrate. Have an evening off. Go for a beer. At least pause before moving onto the next, ‘bigger’ thing.

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Jake P. Mann

@jakepmann

11 months

@DoctorJLam It sounds like one of the toughest jobs on the planet. I hope that the underappreciation and underpay is rectified as soon as possible.

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Jake P. Mann

@jakepmann

1 year

Doing the “school run”. One of the many benefits of doing research is being able to work a bit more flexibly: Start early -> pause work 4-7pm for pick-up, dinner, and bed time -> data analysis & writing after the kids are in bed.

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Jake P. Mann

@jakepmann

4 years

Not every day in research is easy, but today was a good one! Some results to share soon.

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Jake P. Mann

@jakepmann

1 year

As a university employee with an honorary NHS contract, I’m not eligible to take part in the industrial action this week. I am in full support of all junior doctors striking over the next three days. Wrap up warm and best of luck. #payrestoration #JuniorDoctorsStrike

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Jake P. Mann

@jakepmann

2 years

@KateBurkeNHS the older I get the more I realise life is about intermittently partly neglecting one of those things then oscillating back to it to compensate whilst then neglecting something else for a while

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Jake P. Mann

@jakepmann

1 year

Had a brilliant time at BSPGHAN. Delighted to have got the hepatology presentation prize. Lots of work needed to get the work paper-ready.

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Jake P. Mann

@jakepmann

10 months

I've had a few people ask about interview practice for ACFs. I can do an open session one evening next week, if that would be of use? Also, if you would like me to connect you with other people applying for ACFs for practice, then just message me your email. I wrote some

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Jake P. Mann

@jakepmann

10 months

All my typed notes from medschool and MRCP/MRCPCH revision are still available for free here: Note that they are old (so guidelines may have changed), though the fundamentals should still be the same. P.s. And please read the 001_ReadMe

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Jake P. Mann

@jakepmann

10 months

Want some interview practice for ACFs? Wednesday 15th November 2000-2200 via Microsoft Teams We will run it as an open session so everyone listens to each other. The first 9 signing up will be asked questions and then given feedback in front of the rest of the group listening.

Jake P. Mann

@jakepmann

10 months

I've had a few people ask about interview practice for ACFs. I can do an open session one evening next week, if that would be of use? Also, if you would like me to connect you with other people applying for ACFs for practice, then just message me your email. I wrote some

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Jake P. Mann

@jakepmann

11 months

And simultaneously I want to continue to strive towards improvements in our careers, the NHS, the points above and more.

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Jake P. Mann

@jakepmann

1 year

@ollieburtonmed @Doc_IonaCollins If rotation were so absolutely critical to training, all the other countries that don’t have rotation systems would be producing less trained specialists, which clearly isn’t the case. Just like bottlenecks at ST1/4: it’s a choice (for opaque reasons).

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Jake P. Mann

@jakepmann

1 year

@thegradmedic In addition, with appropriate supervision and training, a foundation year doctor can do complex procedures. E.g. lumbar puncture on a 2 month old. Every penny spent on doctors, especially more junior, is an investment.

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Jake P. Mann

@jakepmann

2 years

After some shifts, I find myself hugging my kids just that bit tighter.

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Jake P. Mann

@jakepmann

5 years

Devastated to hear about the passing of Valerio. The hepatology community has lost one its most loved members. He brought major scientific advancements in the field. I am grateful to all he taught me and his kind support. Condolences to all his family and friends. @EASLnews

Bambino Gesù

@bambinogesu

5 years

Con il cuore spezzato diciamo addio al nostro carissimo Prof. Valerio Nobili

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Jake P. Mann

@jakepmann

10 months

@DrEilidhMaria I remember being told on day 1 that no matter our backgrounds we should all expect to find it hard; 50-60% on an exam is a good mark. And I did a 5 year degree, the grad-entry 4 year programme seemed incredibly tough.

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Jake P. Mann

@jakepmann

8 months

🤞🏻 for all getting #SFP jobs released today. 11 years ago I didn’t get any offers at all from my first choice deanery for SFP and things have panned out okay so far, even though I was disappointed at the time. I’ll be offering some suggestions on Making the most of your SFP

Catherine Dominic

@medic_cd

8 months

SFP jobs releasing tomorrow 👇🏽 🔊Our last @NorwichAFP course session Friday 12/01 at 19:00 on ‘Making The Most of Your SFP’ with 3 excellent speakers ranging SFP->ACF->ACL. Come learn about clinical academic careers and what the SFP could mean for you!

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Jake P. Mann

@jakepmann

1 year

@DrAliHosin Similarly, at annual review all we can be is ‘making progress at the expected rate’ It is compounded how we have a lack of belonging / attachment to any one department-due to the rotational system. Usually not in one place long enough for it to matter if we’re really good/bad.

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Jake P. Mann

@jakepmann

2 years

12 days leave starts now. This will be the longest continuous break I’ve had whilst working clinically. Time for a much needed family holiday⛱️

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Jake P. Mann

@jakepmann

4 years

Not sure how I hadn't found any of this before: But a whole series of excellent tools here to generate figures to neatly display the raw datapoints from a whole variety of experiment types. Check it out! Thanks @joachimgoedhart & others

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Jake P. Mann

@jakepmann

1 year

I think that how you treat trainees/colleagues when they leave a department speaks volumes. A card, cake, or even just a cup of tea is symbolic that your valued them. And our most recent/last experience of a place usually has a disproportionate effect on how we remember it.

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Jake P. Mann

@jakepmann

6 years

Finally starting my PhD today @wellcometrust @MRL_Cam #phdlife

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Jake P. Mann

@jakepmann

4 years

I'm proud to be a member of a College that will quickly take a stand on important issues in child health.

RCPCH

@RCPCHtweets

4 years

We are deeply concerned about some of the food packages sent to families who rely on the school meals programme. Thanks to @BootstrapCook and families for sharing. We've written to @GavinWilliamson seeking an urgent review. Statement from @maxdavie 👇👇👇

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Jake P. Mann

@jakepmann

3 years

An major update to our pre-print using lipidomics to understand lipid metabolism in paediatric fatty liver disease: Plasma lipidomics identifies a signature of NAFLD in children that couples with cardiometabolic outcomes in adults

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Jake P. Mann

@jakepmann

11 months

Inspiring day celebrating the career of Prof. David Adams yesterday. Some key ideas I took away: - Follow your curiosity when you observe something that stands out - Important discoveries were met with skepticism when the ideas were first suggested - Great research comes from

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Jake P. Mann

@jakepmann

4 years

That's the last time I claim a meta-analysis will be 'quick and simple'

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Jake P. Mann

@jakepmann

4 years

And I'm delighted to say that this pre-print has now emerged from its chrysalis and is a much improved piece of work available @JHepatology Thanks to all involved in this massive project. @MRC_Epid [Thread to follow at some stage.]

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Jake P. Mann

@jakepmann

1 year

@felicitydevere @RCoANews It is evidently a choice to have a bottleneck at this level across almost all specialities. The numbers quite clearly show a bottleneck isn’t needed at all. If it’s a concern about having too many permanent consultants(¿?) then the bottleneck could still be post-CCT.

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Jake P. Mann

@jakepmann

9 months

🔥 You have until 14th December to apply to the @BHPComms New Consultant Fellowship scheme 🔥 It funds 2 PAs for research for three years to consultants appointed within the last 18 months who hold an MD or PhD Sounds like a great scheme for people who have doctoral level

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Jake P. Mann

@jakepmann

2 years

For clinical-academics: What is one thing you wish you had done differently when starting your first mixed clinical-research post? New job starts soon…

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Jake P. Mann

@jakepmann

5 years

Pleased to share my first preprint! @medrxivpreprint We have performed a meta-analysis to try and establish whether rs641738C>T near MBOAT7 has a role in NAFLD or not... (1/15)

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Jake P. Mann

@jakepmann

10 months

Reading some (excellent) ACF applications the last few days. I'm surprised the number of people who have done PGCert/MSc, and particularly who have done those (usually) expensive courses but not any membership exam parts. That seems strange to me. Am I out of touch??

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Jake P. Mann

@jakepmann

2 years

Tell me you have a toddler, without telling me you have a toddler.

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Jake P. Mann

@jakepmann

2 years

@fortelabs Definitely Essentialism by @GregoryMcKeown Getting organised is best achieved by doing less but better

Book summary – Essentialism by Greg McKeown

Book summary and reflections on Essentialism by Greg McKeown. How can you make your highest contribution? By doing less, not more. And do it better.

jakepmann.com

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Jake P. Mann

@jakepmann

2 years

After 6 years working on/contributing to a project, the main paper has finally been accepted 🎉 Thread & blog on mitofusin 2 in adipose tissue to come…

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Jake P. Mann

@jakepmann

11 months

There have been many jobs/rotations I disliked until this point. There have been times when I’ve thought of changing career/country. And there are few other roles I could imagine myself doing now.

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Jake P. Mann

@jakepmann

2 years

Really pleased with the update and 2nd edition of my Physiology textbook. Artwork is improved and lots of new sections including adipose, appetite, and circadian rhythm.

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Jake P. Mann

@jakepmann

10 months

Having given my opinion on several GRID applications yesterday, my most common suggestions were: - Give specific details about projects/experience. Summarise in 1-2 sentences, rather than using lots of adjectives. - Relate all transferable skills back to the speciality applied

Jake P. Mann

@jakepmann

10 months

Thinking of applying for GRID? (paediatric sub-speciality training). Here are five things to consider: 1. GRID vs. SPIN 2. How many jobs to rank 3. Get rid of perceived barriers 4. Specialty-specific examples 5. Distinguish audit/QIP/research 1. Be crystal clear about the

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Jake P. Mann

@jakepmann

8 months

It’s interesting how cannulation is an absolutely core skill for me currently. Yet, post-CCT I will very rarely use it. I understand why this is the case; it just seems strange to be reaching my ‘peak’ at a skill that I will then not use long-term.

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Jake P. Mann

@jakepmann

4 years

Feeling extremely lucky for nice weather and having a garden.

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Jake P. Mann

@jakepmann

2 years

A few thoughts about career decisions in medicine… 🧵

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Jake P. Mann

@jakepmann

10 months

I am often asked “how did you decide on academic paediatric hepatology?" Remarkably passively and gradually... Like many, by the end of FY2, I had already built a specialty-specific portfolio. So, due to the desire to avoid having wasted input (‘sunk cost bias’) and bad outcomes

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Jake P. Mann

@jakepmann

5 years

This is a conceptually really important study and fits in with much of the work from @MRC_Epid and @MRL_Cam Here is some genetic evidence that ‘lean NAFLD’ is part of the spectrum of lipodystrophy seen in the general population @AASLDtweets #nafld

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Jake P. Mann

@jakepmann

10 months

Your regular reminder that everyone is still trying to figure out what they want to do and who they want to be. I was speaking with a mentee this week and I think they were a little disappointed to hear that I am continuing to make it up as I go along. Do something for a bit,

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Jake P. Mann

@jakepmann

2 years

I've got a 4 spare copies of this book sat on my desk. Would anyone like one? Just send me a message and I can post it out. It is well suited to pre-clinical medical students or physiology revision for MRCP/MRCPCH. #MedTwitter #MedStudentTwitter

Jake P. Mann

@jakepmann

2 years

Really pleased with the update and 2nd edition of my Physiology textbook. Artwork is improved and lots of new sections including adipose, appetite, and circadian rhythm.

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Jake P. Mann

@jakepmann

10 months

It was a few years ago that I realised I had lost almost all my previous identities/aspects to my personality that weren't related to medicine or family (e.g. runner, musician). Getting back into doing running races has been challenging (mostly meaning a lack of sleep) but has

Dr Tanya

@veggieequallife

10 months

What is it with medicine? You came in with lots of interesting things you do outside of work. You came out of med school, became a doctor and struggle to maintain anything else outside of work. 😅🥲🤣

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Jake P. Mann

@jakepmann

1 year

“This is a big deal” is how I’ve felt coming up to ‘step’ in the clinical-academic pathway (e.g. SFP, ACF, PhD fellowship) “No, the next one is actually a big deal” is how I’ve felt once in the role Is this the infamous hedonistic treadmill?

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Jake P. Mann

@jakepmann

2 years

It is interesting that, on the one hand, many feel that training is too long. Yet many experienced, senior clinicians suggest extending training. It seems to me that the key is autonomy.

Simon Fleming 🛠

@OrthopodReg

2 years

I have had 6 ½ years out of training & I don’t regret a thing Anyone telling you that you need to stay on track/time out is wasted time/something something don’t do it, is daft You do you 1 yr #MedEd fellow 1 yr in 🇦🇺 1 year at @RNOHnhs & @ChelwestFT 3.5 yr #PhD #MedTwitter

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Jake P. Mann

@jakepmann

4 years

Data on the role of intestinal LXR-alpha activation in liver fibrosis #ILC2020

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Jake P. Mann

@jakepmann

1 year

Delighted to share a Comment from @ESPGHANSociety and @EASLnews Thanks to the many paediatric and adult hepatologists who have helped put this together.

The Lancet Gastroenterology & Hepatology

@LancetGastroHep

1 year

New Comment from @ESPGHANSociety & @EASLnews - Diagnosis of fatty liver in children should occur in parallel to investigation for other causes of liver disease #fattyliver #livertwitter @jakepmann

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Jake P. Mann

@jakepmann

2 years

@TessaRDavis The happiness project by Gretchen Rubin

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Jake P. Mann

@jakepmann

4 years

I'd like to share a pre-print of our work looking at the function of two protective variants in paediatric NAFLD. We'd be grateful for any feedback! 1/5 @AnnaAlisi @QAnstee @albert_koulman @SamuelFurse

Variants in MARC1 and HSD17B13 reduce severity of NAFLD in children, perturb phospholipid metabol...

Background & aims Genome-wide association studies in adults have identified variants in HSD17B13 and MARC1 as protective against NAFLD. It is not known if they are similarly protective in children...

www.medrxiv.org

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Jake P. Mann

@jakepmann

10 months

Five things I learnt doing a basic science PhD as a paediatrician: [In retrospect all seem really obvious.] 1. Data organisation. It took time and failure to learn how to store all the different data types (gel images, plate data, transcriptomics, microscope images etc.) Even

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Jake P. Mann

@jakepmann

1 year

Trying my first formal meta-analysis of RNAseq today. First DESeq2 complete ✅ Two more to go then the combining.

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Jake P. Mann

@jakepmann

10 months

Why I think doctors are in an ideal position to lead a fulfilling life: Fulfillment comes from doing meaningful things, building relationships, and the satisfaction from striving towards something challenging. The things that will matter in three decades time come from working

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Jake P. Mann

@jakepmann

1 year

Grant 1 - submitted ✅ Grant 2 - submitted ✅

Jake P. Mann

@jakepmann

1 year

Grant 1 - submitted ☑️ Grant 2 - 90% done and awaiting supervisor's comments

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Jake P. Mann

@jakepmann

11 months

How I looked up information about clinical-academic careers: - General overviews (e.g. CATCH) - Specific programmes (e.g. ECAT, GW4-CAT) - Individual institutions (e.g. Crick) and then read about the careers of inspirational clinician-scientists [All links in 🧵 below👇👇]

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Jake P. Mann

@jakepmann

10 months

👇👇👇 Lots of interesting discussion below about portfolio inflation in AFP/ACF applications. My TL;DR: need to find a way to support people to do research at all stages... - Just want to try it out and see if its for them - Develop ideas into application for PhD fellowship -

Sanchit Turaga

@srturaga

10 months

@jakepmann How do you feel about the portfolio inflation happening in academic applications? A lot of successful AFPs and ACFs seem to have PhDs prior to applying now, reflecting competition. Sometimes it feels like this detracts from the original purpose of this being a pathway into

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Jake P. Mann

@jakepmann

11 months

Several ACFs in paediatrics available in the West Midlands. Great jobs with excellent opportunity to make a long-term contribution @WMPaeds @PramNetwork @unibirmingham @unibirm_MDS

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Jake P. Mann

@jakepmann

11 months

Your regular reminder: Everyone is out there doing their best. If it’s not very good, it’s because we don’t know how to do it better, are having a tough day, or need more training.

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Jake P. Mann

@jakepmann

9 months

Just for the record, I am someone who likes to focus on 'meaningful' or fun things. I would not consider ePortfolio either. (Meaningful learning/development/reflection can occur without the filling in of a form or linking on an electronic curriculum.) i.e. I dislike ePortfolio as

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Jake P. Mann

@jakepmann

1 year

I've decided to switch focus to work on cholangiopathies - bile duct diseases. Here's why...

Why I am researching bile duct diseases

Bile duct diseases are serious conditions that have a high risk of causing cirrhosis. They are in need of research to find new, effective treatments.

jakepmann.com

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Jake P. Mann

@jakepmann

10 months

I found Talk like TED a really useful book for giving presentations. It’s key points: 1You must be truly passionate about what you are talking about. This will translate into mastery of the topic 2Tell three stories, or make three key points. Three is the magic number. •But

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Jake P. Mann

@jakepmann

1 year

Sometimes I wonder whether a chronic lack of time for general chat / team coffee should be exception report-able… To recognise that short staffing and workload has a cumulate effect on the vital informal learning and team bonding that happens in this ‘down time’

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Jake P. Mann

@jakepmann

4 years

Here's a pre-print of our work using lipidomics to study NAFLD in children, not yet peer reviewed but we think the results are interesting. @SamuelFurse @albert_koulman @Matt_Zilbauer @AnnaAlisi

medRxiv

@medrxivpreprint

4 years

Plasma lipidomics distinguishes NASH and fibrosis from simple fatty liver in children #medRxiv

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Jake P. Mann

@jakepmann

10 months

Spent two days this week doing interviews for the SFP and I was extremely impressed by the calibre of the candidates. Well done to all.

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Jake P. Mann

@jakepmann

5 years

***Looking for feedback & comments on a preprint*** Ever wondered what determines whether an animal model 'responds' to treatment with a drug? Well, we've done a large meta-analysis of rodent models of NAFLD and found some surprising results... (1/10)

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Jake P. Mann

@jakepmann

1 year

The best ☕️ and 🍪 that money can’t buy. @GiveBloodNHS

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Jake P. Mann

@jakepmann

8 months

The downside of nights is that it’s time “out of speciality” so for me it’s general paediatrics + ward cover of specialities. Of course it would be lovely to just do liver overnight too, but I do get to CCT in general paeds so this is part of the job. So when seeing the n^th

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Jake P. Mann

@jakepmann

2 years

@Medic_Russell I recently wrote a few suggestions down. Good luck!!

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