Pablo Corral MD @drpablocorral Twitter profile

Last Seen Profiles

@stw_pdg

@hjnumetal

@RaulIUR

@JohnCarrol92593

@varaayanna

@Palmarine128

@tc8211

@Andy59089318

@seal_rv

@VolumeEM1

@KCvwPCZ33r79qtY

@ZhangHaoBar0725

@galery_basah10

@suzu71221

@NapoliVHS

@ZhuiShan43297

@EmeryWolfg93737

@axiz_and_nico

@opdaiIy

@maom33131

@MAO2090999

@VirtualSoil

@miavmoore28

@jandakembangstw

@Rafaprodz

@_wzal

@karajunko170451

@8ch_piano

@becausethisfilm

@lmfYavRe3442440

@5409kuroyuki

@GIKOH

@aslan_501

@inoti_0120

@ishibe_kin

@newsclub1134

Pablo Corral MD

@drpablocorral

2 months

👉Association of a Low-Carbohydrate High-Fat Diet With Plasma Lipid Levels and CV Risk 🙏 Finally GOOD SCIENCE!! 👆"Consumption of a LCHF diet was associated with increased LDL-C and apoB levels, and an increased risk of incident MACE" 👋Congrats @LiamBrunham and col. 🔓Open

76

169

470

Pablo Corral MD

@drpablocorral

1 year

👉 Atherosclerosis is NOT an inflammatory condition ☝️Inflammation plays an important role, enhancing and accelerating the process, but the first and main driver is ApoB 👉Without ApoB, NO Atherosclerosis

43

119

456

Pablo Corral MD

@drpablocorral

4 years

😳 Hermoso momento; paciente que no veo hace 4 años 🤔 Me envía WA (ni registrado el número tengo) Le aviso a mi secretaria que la llame y le comente que es un acto médico y debe abonar la consulta 🤷🏻‍♂️Todavía estoy esperando que me confirme cuando hacemos la Videoconsulta 🤦🏻‍♂️

81

47

432

Pablo Corral MD

@drpablocorral

4 years

@KeniaBal De quien es la responsabilidad? Del dueño del bar que pudo abrir luego de 5 meses sin trabajar o de la persona que seguramente fue a tomar algo estando enferma?

10

403

Pablo Corral MD

@drpablocorral

4 years

😂🤣😂🤣🤣

9

66

400

Pablo Corral MD

@drpablocorral

2 months

👉 Aspirin Use for Primary Prevention Among US Adults With and Without Elevated Lp(a) ☝️Regular aspirin use was associated with a 52% lower risk of ASCVD mortality among adults without clinical ASCVD who had elevated Lp(a). These findings suggest that measurement of Lp(a) may

23

145

378

Pablo Corral MD

@drpablocorral

1 month

👉ApoB triumphs once more over LDL-C and non-HDL-C in risk prediction: ready for guidelines? ☝️ In conclusion, the era of focusing solely on LDL-C for assessing cholesterol-driven risk is coming to an end. ☝️These findings advocate for the integration of apoB as a central

16

110

377

Pablo Corral MD

@drpablocorral

2 months

Atherosclerosis, the number one killer worldwide, begins much earlier than when it can be detected by coronary artery calcium (CAC) score

13

91

346

Pablo Corral MD

@drpablocorral

1 month

👉 First slide at #EASCongress2024 🤷🏻‍♂️ Any other questions? 🙌 Best way to kick-off the best Atherosclerosis/Lipids/CV Prevention Event worldwide @society_eas @ProfKausikRay

30

78

341

Pablo Corral MD

@drpablocorral

3 years

😡Que vergüenza lo que han hecho con los médicos y el examen de Residencias. Una vez más. No tienen ni la remota idea que significa esto para un médico recién recibido. Pasó en 2020 y ahora tb 2021. @msalnacion

8

128

335

Pablo Corral MD

@drpablocorral

4 years

🙏🏻🙏🏻 Necesitamos más RESPONSABILIDAD en la manejo de la información. Esta captura me la acaba de enviar un paciente. Esto está definitivamente MAL. 😡Vean los potenciales efectos adversos de la #ivermectina @Andrea_Gentil #COVID19

31

167

312

Pablo Corral MD

@drpablocorral

2 years

Aclarando conceptos básicos: 1-No hay objetivo de cHDL 2-Cuanto más bajo cLDL, mejor 3-No existe el colesterol “bueno” y “malo” 4-Tener cHDL elevado no “asegura” estar protegido de ECV 5-Sin trastorno lipídico, no hay aterosclerosis 6-El valor fisiológico del cLDL es 30-50 mg/dL

8

68

319

Pablo Corral MD

@drpablocorral

8 months

☝️All patients receiving statins (regardless of dose) should be associated with ezetimibe 👉Low cost 👉No side effects 👉20% LDLc reduction

23

75

309

Pablo Corral MD

@drpablocorral

3 years

Cuando entendamos que la restricción de circular en algunos horarios NO depende de posturas o ideologías políticas, sino de una necesidad sanitaria, vamos a haber podido avanzar como Sociedad

9

66

295

Pablo Corral MD

@drpablocorral

3 years

😳Alberto Fernández: "el sistema de Salud privado se relajó y ocuparon camas que hoy servirían para tratar el Covid" 😡 ...y un día se nos ocurrió salir a buscar infartos, cánceres, ACV, meningitis e internarlos...

20

64

271

Pablo Corral MD

@drpablocorral

6 months

👉Non-HDL-cholesterol in dyslipidemia: Review of the state-of-the-art literature and outlook 1️⃣Non-HDL-C is a consistent and reliable residual risk predictor of ASCVD and all non-HDL-C contributing lipoproteins independently promote ASCVD. 2️⃣Non-HDL-C is recommended as a

11

93

233

Pablo Corral MD

@drpablocorral

3 years

Pido perdón 🙏🏻 Me relajé y casi interno a mi paciente con Ca de pulmón y mtts cerebrales. A quien se le hubiese ocurrido ocupar una cama en este momento de la pandemia!

10

57

233

Pablo Corral MD

@drpablocorral

1 year

👉After vaccines and antibiotics, STATINS are probably the drugs that have prevented the most deaths in the history of modern medicine

22

51

231

Pablo Corral MD

@drpablocorral

3 years

👤FH patient 🧬 LDLR mutation 💊 Rosuvastatin 40 + Ezetimibe 10 + Evolocumab 140 💪Xanthelasma & Xanthoma regression #knowFH #LDLc #atherosclerosis

14

64

227

Pablo Corral MD

@drpablocorral

2 years

👉Hypertriglyceridaemia: an update (2022) ☝️A must read review 🔑Open access “Extreme hypertriglyceridaemia associated with pancreatitis and/or pregnancy is a lipid emergency and requires urgent secondary care management”

4

80

226

Pablo Corral MD

@drpablocorral

6 months

☝️The main Cardiovascular Atherosclerotic RESIDUAL RISK is simple… 👉We are starting TREATMENT TOO LATE in life 👉“If the entire population maintained LDL concentrations akin to those of a neonate (or to those of adults of most other animal species), atherosclerosis might well

17

75

221

Pablo Corral MD

@drpablocorral

9 months

👉Lipid-lowering in diabetes: An update 🔓Open access "Most patients with diabetes are at high or very high CVD risk" "Dyslipidemia, characterized by hypertriglyceridemia, low levels of HDL-C, normal to slightly elevated levels of LDL-C and apo B levels, and the accumulation

1

80

214

Pablo Corral MD

@drpablocorral

1 year

👉Statins revisited: therapeutic applications beyond lipid lowering?

4

57

213

Pablo Corral MD

@drpablocorral

10 months

☝️Five things to know about ... 👉ApoB in cardiovascular risk assessment 🙌 By Robert Hegele & Allan Sniderman

6

58

210

Pablo Corral MD

@drpablocorral

4 years

🤔 ¿El plasma de convalescientes salva vidas?: NO se sabe 🤔¿El ibuprofeno nebulizado salva vidas? NO se sabe 🤔¿La ivermectina salva vidas? NO se sabe 😲¿Es perjudicial usar este tipo de tratamientos SIN evidencia? 😩SI, totalmente dañino y perjudicial!

11

108

204

Pablo Corral MD

@drpablocorral

2 months

👏One of the most important and necessary manuscripts published this year. A MUST READ! 🤩Allan Sniderman and col. 👉Discordance among apoB, non–high-density lipoprotein cholesterol, and triglycerides: implications for cardiovascular prevention ☝️The present prospective

9

60

196

Pablo Corral MD

@drpablocorral

5 months

👉Aspirin and CV risk in Individuals With Elevated Lp(a): The MESA ☝️Aspirin use was associated with a lower risk for cardiovascular events among participants with elevated lipoprotein(a) and free of baseline cardiovascular disease. These results suggest that aspirin may have

8

70

193

Pablo Corral MD

@drpablocorral

3 months

👉Atherosclerotic coronary plaque regression from lipid-lowering therapies: A meta-analysis and meta-regression ☝️The Authors examined the efficacy of all current LLTs in plaque regression based on PAV, TAV, lumen, vessel, plaque volumes, EEM, FCT, and lipid arc. Subgroup

13

53

189

Pablo Corral MD

@drpablocorral

3 years

👉Do you really need more evidence? LDLc “CAUSE” Atherosclerosis!

11

57

184

Pablo Corral MD

@drpablocorral

7 months

☝️If you want to read and learn the most basic and at the same time better updated lipidology, you must memorize every word of this manuscript 🙌“We must stop thinking of a heart attack as a disease. The real disease is atherosclerosis. An atherosclerotic heart attack is a

13

52

178

Pablo Corral MD

@drpablocorral

3 years

😳Un jugador de fútbol profesional da positivo #COVID19 . Lo aíslan 10 días. Ok. Día 11 lo hacen jugar un partido de 90 min. Hasta que no pase una tragedia y muera un jugador en pleno partido, no vamos a parar con esta locura.

16

36

179

Pablo Corral MD

@drpablocorral

3 years

😊This is a unique talent...summarize in a few words the complex process and history of atherosclerosis...worth every word...definitely a must read comment. Peter Libby.

7

44

176

Pablo Corral MD

@drpablocorral

4 months

👉Effect of lipid-lowering therapies on C-reactive protein (CRP) levels: a comprehensive meta-analysis of RCT ☝️ Statins, bempedoic acid, ezetimibe, and omega3FAs significantly reduce serum CRP concentration, independently of LDL-C reductions. ☝️The impact of this

12

61

170

Pablo Corral MD

@drpablocorral

6 months

👉Conquering cholesterol: a report from the front lines ☝️Strong genetic and observational data, along with the results of clinical lipid-lowering trials, have established the causal link between cholesterol and atherosclerosis. If the population maintained the cholesterol

14

36

169

Pablo Corral MD

@drpablocorral

5 years

I would like to invite all LDL / statin deniers to the ICU and witness the drama when a young man / woman with familial hypercholesterolemia suffers a myocardial infarction, stroke or even dies. A whole family destroyed. Only one culprit (LDLc) and one wasted tool (statins)

27

37

163

Pablo Corral MD

@drpablocorral

4 months

For those who think, imagine, or believe that LDLc doesn't matter in atherosclerosis and also believe that if you have no other CV risk factors, LDLc is not important 👉Impact of optimal cholesterol levels on subclinical atherosclerosis in the absence of risk factors in young

14

45

161

Pablo Corral MD

@drpablocorral

4 years

💉 Vacunas en Fase 3 contra 🦠 SARS-CoV-2 al 3/8/2020 #COVID19 👇👇👇

0

71

169

Pablo Corral MD

@drpablocorral

3 months

👉Aspirin for Primary Prevention in patients with Elevated CAC (Coronary Calcium Score): A systematic review of current evidences ☝️Evidence shows a net harm for usage of aspirin in low ASCVD risk (<5%) irrespective of CAC score 🤔Maybe in those patients with High Lp(a)

14

49

166

Pablo Corral MD

@drpablocorral

2 years

“Without elevated LDL, atherosclerosis would likely be an orphan disease” The dawn of a new era of targeted lipid-lowering therapies

3

58

168

Pablo Corral MD

@drpablocorral

3 years

La publicación de los datos de fase 3 en Lancet de la vacuna #SputnikV no debe hacernos perder el foco en que siempre debemos exigir transparencia y publicación de resultados. Hoy ganó la Ciencia, se generó confianza y fue un paso hacia adelante. Se hizo lo que se debía hacer.

11

29

162

Pablo Corral MD

@drpablocorral

2 months

🙌Our new manuscript just published 👉Impact of Lp(a) Levels on CV Risk Estimation ☝️Lp(a) evaluation could be useful to stratify CVR. -Our study evaluated, for the first time in our region 🇦🇷, a new predictive tool that includes the value of Lp(a) among its explanatory

17

31

163

Pablo Corral MD

@drpablocorral

7 months

👉Low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol and apolipoprotein B for cardiovascular care ☝️The conventional lipid panel has five markers: total cholesterol, TG, non-HDL-C, LDL-C and HDL-C. ☝️Too many numbers and too many choices. ☝️Why not

14

42

157

Pablo Corral MD

@drpablocorral

4 months

👉Eradicating Atherosclerotic Events by Targeting Early Subclinical Disease: It Is Time to Retire the Therapeutic Paradigm of Too Much, Too Late ☝️"We must stop thinking of a heart attack or ischemic heart failure or an ischemic stroke as a disease. The real disease is

7

35

159

Pablo Corral MD

@drpablocorral

2 months

👉The current landscape for diabetes treatment: Preventing diabetes-associated CV risk 👏A must read manuscript 1️⃣ Subjects with type 2 diabetes have a substantial excess of atherosclerotic cardiovascular disease (ASCVD)-related events. 2️⃣ The understanding of the

10

49

156

Pablo Corral MD

@drpablocorral

2 months

☝️Please stop talking about the “Lipid Hypothesis” There is no such thing 👉It's an incorrect and outdated way to refer to the CAUSAL relationship between LDLc (ApoB) and Atherosclerosis (CHD) @society_eas

32

36

147

Pablo Corral MD

@drpablocorral

1 year

👉Eliminating atherosclerotic cardiovascular disease residual risk ☝️“The goal should be to make atherosclerosis a rare disease. We have the means to do so; should it not be our top priority?”

3

40

154

Pablo Corral MD

@drpablocorral

4 years

Es una “gripe más”. Hospital en Sudafrica. Un enfermo con SARS-CoV-2 va a guardia. Resultado=125 contagiados (entre médicos, enfermeros, personal y pacientes).15 muertos.

2

78

149

Pablo Corral MD

@drpablocorral

7 months

👉The association of lipoprotein (a) with coronary artery calcification: A systematic review and meta-analysis ☝️Coronary artery calcification is a physiological characteristic of atherosclerosis. ☝️Increased lipoprotein(a) is a risk factor for subclinical cardiovascular

0

60

152

Pablo Corral MD

@drpablocorral

5 years

LDL-c IS the cause of Atherosclerosis

27

52

149

Pablo Corral MD

@drpablocorral

2 months

👉High Lp(a): Actionable strategies for risk assessment and mitigation ☝️This review focuses on the identification and clinical management of patients with high Lp(a). Specifically, the authors highlight the clinical value of measuring Lp(a) and its use in determining Lp(a)

4

56

151

Pablo Corral MD

@drpablocorral

2 years

Oral PCSK9 inhibitors: New horizons A novel oral PCSK9 inhibitor, MK-0616, showed substantial reduction in LDL-C levels and was well tolerated, according to early trial data. @PCSK9Forum More data #ACC23 LCBT @ACCinTouch

4

41

150

Pablo Corral MD

@drpablocorral

3 years

Working Mechanisms of LDLc Lowering Therapies

1

51

148

Pablo Corral MD

@drpablocorral

1 year

👉FDA approves CV version of colchicine for patients with residual inflammatory risk

9

46

147

Pablo Corral MD

@drpablocorral

1 year

A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins “A Goldstein & Brown classic”

5

53

149

Pablo Corral MD

@drpablocorral

3 months

👏Excellent article; a must read! 👉Lipid-Lowering Therapy after Acute Coronary Syndrome ☝️There is a sufficient amount of evidence that the immediate combination of LLT after ACS leads to early LDL-C goal achievement without any safety concerns. On top of it, intensive LLT

1

57

147

Pablo Corral MD

@drpablocorral

1 year

👉The main driver of subendothelial lipoprotein (ApoB) deposition is the circulating concentration of ApoB particles. ☝️Inflammation and endothelial dysfunction are enhancers and accelerators of the atherosclerosis process, but ApoB is always needed to witness this process.

8

34

143

Pablo Corral MD

@drpablocorral

11 months

👉Documento de Posición @LipidosSal sobre Efectos Adversos e Intolerancia a Estatinas 🇲🇽🇩🇴🇨🇱🇺🇾🇨🇴🇦🇷 13 autores de 6 países de #LATAM ☝️Primer documento habla hispana sobre Intolerancia a Estatinas 🔑 Acceso libre

7

61

145

Pablo Corral MD

@drpablocorral

1 year

Moderate-intensity statin with ezetimibe vs. high-intensity statin in patients with diabetes and atherosclerotic cardiovascular disease in the RACING trial

6

56

141

Pablo Corral MD

@drpablocorral

6 months

👉Dietary fat quality, plasma atherogenic lipoproteins, and atherosclerotic cardiovascular disease: An overview of the rationale for the dietary recommendations for fat intake 👏Evidence Based Medicine ☝️Dietary fat quality is the main environmental determinant of plasma

9

43

137

Pablo Corral MD

@drpablocorral

4 years

Te llamaré et al. 😝😂🤣

5

20

141

Pablo Corral MD

@drpablocorral

1 year

💊🚫Statin Intolerance 👉From de detractors of these wonderful drugs to the management of this clinical situation

3

43

138

Pablo Corral MD

@drpablocorral

1 year

👉The “Zero-LDL Hypothesis” ☝️Towards Extremely Low LDL Concentrations 👏Fantastic summary, must read (2017) Congrats @lluismasana @Drlipid @JohnKastelein @dan_soffer @LaleTokgozoglu @PeterAttiaMD @ProfKausikRay @BNordestgaard @society_eas

4

40

138

Pablo Corral MD

@drpablocorral

3 years

👉El colesterol es fundamental para múltiples funciones en el cuerpo humano (síntesis de membranas celulares, formación de vitaminas liposolubles, ácidos biliares y hormonas) 👉Ese colesterol NO se utiliza desde el LDLc, sino desde el HDLc. 👉NO necesitamos de LDLc para esto!

6

31

137

Pablo Corral MD

@drpablocorral

9 months

👉Triglyceride-rich lipoprotein remnants, low-density lipoproteins, and risk of coronary heart disease: a UK Biobank study 🔓Open Access The strength of association of apoB with CHD risk is not uniform; rather, it depends on which particle the apoB resides; TRL/remnant

8

41

137

Pablo Corral MD

@drpablocorral

3 years

The lower, the better… 👇👇👇 Cardiovascular Benefit of Lowering Low-Density Lipoprotein Cholesterol Below 40 mg/dL

6

34

135

Pablo Corral MD

@drpablocorral

6 months

Comparison of the Efficacy of Ezetimibe Combination Therapy and High-Intensity Statin Monotherapy in Type 2 Diabetes “Adding ezetimibe to a moderate-intensity statin in patients with diabetes, a high-risk group for ASCVD, has a greater LDL-lowering effect and a greater primary

5

39

135

Pablo Corral MD

@drpablocorral

12 days

👉Fenofibrate and Diabetic Retinopathy; New Evidence from a RCT ☝️The LENS Trial ☝️ In people with diabetes and early retinopathy, fenofibrate led to a 27% lower risk of progression of, or treatment for, diabetic retinopathy or maculopathy compared with placebo over 4 years.

11

50

136

Pablo Corral MD

@drpablocorral

6 months

👉The year in cardiovascular medicine 2023: The top 10 papers in dyslipidaemias @AL_Catapano @LaleTokgozoglu @society_eas

1

46

133

Pablo Corral MD

@drpablocorral

5 months

👉Ketogenic diet and cardiovascular risk – state of the art review ☝️The ketogenic diet presents the potential for rapid short-term body mass, triglycerides level, Hb1Ac, and blood pressure reduction. ☝️The ketogenic diet's efficacy for weight loss and metabolic changes is

20

48

132

Pablo Corral MD

@drpablocorral

9 months

👉Non-HDL-C in dyslipidemia: Review of the state-of-the-art literature ☝️…non-HDL-C can become a co-primary or primary goal in dyslipidemia management 🤩An outstanding document @ProfKausikRay @LaleTokgozoglu @society_eas @BNordestgaard

1

50

132

Pablo Corral MD

@drpablocorral

3 years

Una vergüenza que se juegue Boca-River. Todo el plantel de River debería estar aislado como burbuja. Son claros “contactos estrechos” de los positivos (si es que no son falsos negativos).

14

20

129

Pablo Corral MD

@drpablocorral

11 months

👉Low-Dose Aspirin and Risk of Stroke and Intracerebral Bleeding in Healthy Older People ☝️ A statistically significant 38% increase in intracranial bleeding The difference in incidence of ischemic stroke was not statistically significant

6

45

129

Pablo Corral MD

@drpablocorral

8 months

👉Icosapent ethyl for hypertriglyceridaemia and atherosclerosis: greater RESPECT for increased therapeutic use ☝️In summary, we now have evidence from an amalgamation of sources, such as randomized clinical trials, prospective imaging studies, and basic science experiments, that

4

42

129

Pablo Corral MD

@drpablocorral

14 days

👏A Must Read Review 👉Genetics and Pathophysiological Mechanisms of Lipoprotein(a)-Associated Cardiovascular Risk ☝️In summary, lipoprotein(a) is a unique lipoprotein with multiple structural features that give rise to a vast array of potential pathogenic effects, likely

1

44

130

Pablo Corral MD

@drpablocorral

7 months

👉Moderate-intensity statin plus ezetimibe vs high-intensity statin according to baseline LDL-C in the treatment of atherosclerotic cardiovascular disease: A post-hoc analysis of the RACING randomized trial 👉In conclusion, among ASCVD patients from the RACING trials which

2

43

126

Pablo Corral MD

@drpablocorral

4 months

👉Hyperlipidaemia in diabetes: are there particular considerations for next-generation therapies? ☝️New-generation therapies targeting circulating lipoparticles have recently been approved. ☝️The main molecular targets are PCSK9, ATP citrate lyase, apoC-III and ANGPTL3.

5

49

126

Pablo Corral MD

@drpablocorral

19 days

👉Cholesterol paradox for cardiac events: is age the missing link? 🙏🏻 Please stop discussing this topic. ☝️The cholesterol paradox does not exist! ☝️Non-cardiovascular factors may drive mortality in patients with lower cholesterol post-PCI. The inverse relationship between

47

20

128

Pablo Corral MD

@drpablocorral

6 months

👉Coronary Atherosclerosis Causes, Consequences, and the Passage of Time A must read editorial by Peter Toth and Allan Sniderman ☝️Trapping of apoB particles within the arterial wall is the root cause of atherosclerosis and the level of the apoB lipoproteins within plasma is

12

34

125

Pablo Corral MD

@drpablocorral

1 year

Moderate-intensity statin with ezetimibe combination therapy showed similar CV benefits to those of high-intensity statin monotherapy with lower intolerance-related drug discontinuation or dose reduction in elderly Post hoc analysis of the RACING

7

36

124

Pablo Corral MD

@drpablocorral

1 year

👉Mendelian randomisation analysis and CVD 🤺CRP vs. LDLc ❌CRP concentration itself is unlikely to be even a modest causal factor in CHD ✅ LDL-C has both a causal and cumulative effect on the risk of CVD

14

27

122

Pablo Corral MD

@drpablocorral

8 months

👉A historical perspective on the discovery of statins ☝️Prof. Akira Endo deserves the Nobel Prize #nobelprizetoakiraendo Cholesterol is essential for the functioning of all human organs, but it is nevertheless the cause of coronary heart disease. Over the course of nearly a

6

41

121

Pablo Corral MD

@drpablocorral

9 months

👉Aspirin and lipoprotein(a) in primary prevention 👏Another great review about this hot topic ☝️Must read

5

38

122

Pablo Corral MD

@drpablocorral

8 months

👉Ups and downs in PCSK9 inhibition in the cardiovascular arena: a review ☝️PCSK9i represent a potent class of lipid-lowering therapies that are well tolerated and effective in a wide group of patients with high-risk atherosclerotic cardiovascular disease. ☝️Ongoing studies of

5

38

122

Pablo Corral MD

@drpablocorral

1 year

Impact of lipid lowering on coronary atherosclerosis moving from the lumen to the artery wall @ATHjournal @ProfSNicholls @society_eas

2

37

120

Pablo Corral MD

@drpablocorral

8 months

🙌Our manuscript finally published 👉Stratification in Heterozygous Familial Hypercholesterolemia: Imaging, Biomarkers, and Genetic Testing Great collaboration with @lschreier1 @caguilarsalinas @magabrielama83 Valeria Zago 👉 Not all FH patients face the same cardiovascular

16

37

120

Pablo Corral MD

@drpablocorral

7 months

👉Bempedoic acid – how will it shape the future lipid-lowering landscape? ☝️Mode of action, evidence, and clinical use 🔓Open access

2

41

117

Pablo Corral MD

@drpablocorral

29 days

🙌 Our new manuscript is published 👉Exploring the Interplay between Diabetes and Lp(a): Implications for Cardiovascular Risk ☝️ Elevated levels of Lp(a) are associated with an increased risk of cardiovascular atherosclerosis, and coexisting diabetes status confers an even

9

28

119

Pablo Corral MD

@drpablocorral

2 months

👉Colchicine’s Role in CVD Management ☝️Colchicine exerts pleiotropic anti-inflammatory effects on assembly of the NLRP3 inflammasome and various neutrophil functions. Based on multiple, large randomized controlled trials, individuals with coronary artery disease and preserved

4

40

118

Pablo Corral MD

@drpablocorral

10 months

👉Treatment of Lp(a): Is It the Future or Are We Ready Today? 🔑Open access

4

41

117

Pablo Corral MD

@drpablocorral

3 years

LDLc causes Atherosclerosis…and also we have to understand this basic concept 👇👇👇

6

25

115

Pablo Corral MD

@drpablocorral

1 year

👉Lifelong endurance sport participation is not associated with a more favourable coronary plaque composition compared to a healthy lifestyle This is SCIENCE…

7

33

116

Pablo Corral MD

@drpablocorral

9 months

👉ApoB, LDL-C, and Non-HDL-C ☝️The fact that apoB can be measured more accurately, precisely, and selectively than LDL-C and non-HDL-C using widely available, inexpensive, standardized methods argues strongly for its broad application in clinical care

2

33

113

Pablo Corral MD

@drpablocorral

1 year

👨🏻‍⚕️4 patients saw last week 📈All of them with LDLc > 200 md/dL 👨‍👩‍👧‍👧All of them w/ family history of high LDLc and premature CVD 🧬 Familial Hypercholesterolemia (FH) detected 👨‍👩‍👦 Cascade screening mandatory 💊💉High intensity LLT prescribed #KnowFH

6

31

112

Pablo Corral MD

@drpablocorral

5 years

My daughter was accepted and entered Medical School today. Happy and proud for her. No better news than that for me today 😭❤️😍 @Corral_Agus

16

2

111

Pablo Corral MD

@drpablocorral

3 years

👉Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis @DLBHATTMD @virani_md @ErinMichos @rblument1 @khurramn1 @mmillermd1 @CBallantyneMD

Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis

Omega-3 FAs reduced cardiovascular mortality and improved cardiovascular outcomes. The cardiovascular risk reduction was more prominent with EPA monotherapy than with EPA+DHA.

www.thelancet.com

3

42

110

Pablo Corral MD

@drpablocorral

7 months

👉Beyond Lipoprotein(a) plasma measurements: Lipoprotein(a) and inflammation ☝️It would be of interest to investigate whether anti-inflammatory drugs, such as canakinumab, or colchicine lower plasma Lp(a) levels, and as such are more effective in reducing CVD in patients with

2

28

113

Pablo Corral MD

@drpablocorral

6 months

👉Omega-3 Fatty Acids for Cardiovascular Event Lowering @gabrielsteg @DLBHATTMD 🔓Open access

2

43

113

Pablo Corral MD

@drpablocorral

2 months

👉Subclinical Atherosclerosis: What Is it? 🤔Can it Be Defined at the Histological Level? ☝️The presence of lipid within artery wall is defined as atherosclerosis ☝️Subclinical atherosclerosis includes all types of plaques with or without thrombosis in the absence of any

8

35

114

Pablo Corral MD

@drpablocorral

4 months

👉Obesity, Dyslipidemia, and Cardiovascular Disease Risk: A Joint Clinical Perspective from the Obesity Medicine Association and the National Lipid Association 2024 🔓Open Access @nationallipid @society_eas

1

53

112

Pablo Corral MD

@drpablocorral

11 months

👉ApoB, LDLc, and Non-HDLc ☝️The fact that apoB can be measured more accurately, precisely, and selectively than LDL-C and non-HDL-C using widely available, inexpensive, standardized methods argues strongly for its broad application in clinical care

3

44

109