🚨Job update🚨
THRILLED to announce that today, I was appointed as the new Else Kröner Fresenius Full Professor and inaugural Chair of Translational Nutritional Medicine at Technical University Munich 🤓🍾🥂❤️☀️ O’zapft is!
OTD 10 years ago, I moved to USA for a postdoc. It was an outstanding experience, but also the most difficult challenge of my life. The last 10 years have been rough, I lost my best friend, and the love of my life twice, but science gives me hope every day❤️
Our new 2023 group pic - as my beard is becoming whiter the lab is being continuously rejuvenated. While I’m sad to see my students leave I’m very proud when they spread their wings and move on to new challenges.
This is the way.
Extremely honored to receive the 2021
#Obesity
Research Award
@DAG_Presse
- took me a while to digest this news.
#Obesity
is one of THE major challenges of our time &
@BarteltLab
will continue its ongoing mission to understand the nature & power of
#metabolism
!
Today, we report that chronic intermittent fasting impairs β-cell maturation and function in adolescent mice. Using scRNA-seq of islets we define a β-cell maturation score, which was linked to T1D in humans. 👇
In the first 6 months of 2024 our lab peer-reviewed 40 manuscripts. Underestimating we spent 4 h per MS, this makes 160 h pro bono work.
If we charged the publishers, this would amount to a decent salary for a PhD student.
Happy weekend!
What fuels thermogenesis🔥?
Ummmm - let's say, it depends - see our comment on an elegant new study in Nature Metabolism
Here a link to the free view-only version:
Today, we report a novel adaptive mechanism of muscle biology, remodeling of the ubiquitin-proteasome system in obesity, and its global regulation by the transcription factor Nfe2l1 🧵
Today, we say farewell to our PhD student
@nwillemsen95
who will continue her postdoctoral career
@KingsCollegeLon
🇬🇧. There isn’t enough space here to say how proud I am of you and your achievements. I have no doubt you’ll do great, best of luck🖖🍀🧿
Being a PI and mentor is sometimes challenging as there isn’t really any training and you don’t get a lot of feedback so I’m very happy about the birthday card the lab wrote me ❤️
Out now in The EMBO Journal:
Uncoupling is important for brown fat but is coupled respiration regulated, too?
We found that IF1 is a cold-regulated switch of ATP synthase hydrolytic activity to support thermogenesis
👇
Today, we report a new imaging approach that provides remarkable contrast deep within tissues for contrast agent-free visualization of physiology in whole animals and intraoperative imaging in humans:
Shortwave infrared Raman scattering
👇
Fascinated by the biology of fat cells I was asked by
@Ullstein
publishing to write a popular science book about
#metabolism
,
#diet
and
#obesity
- VERY happy that the work is done now and the book is going to be released Jan 12th 2021 👇 - in German
😱Today I’m having a very important
#proudPI
milestone moment - first student out for postdoc interview (hope student doesn’t see this tweet but let’s all wish best of luck 😜🍀🧿) it feels like as if I was being interviewed 😅😬
#AcademicTwitter
Chlorophyll and Hemoglobin
The major difference is that plant blood carries a Magnesium (Mg) molecule where our blood contains a Iron (Fe) molecule.
Magnesium is what is responsible for making plant blood green, and iron is what makes our blood red.
JUST published:
HAND2 is a novel
#obesity
-linked adipogenic transcription factor regulated by glucocorticoid signalling
BIG THX to lead author Dr. Maude Giroud👩🔬, our generous collaborators,
@AvHStiftung
@ERC_Research
and the editorial team
@DiabetologiaJnl
for a fair review
Panorama view from
@BarteltLab
on beautiful Bavarian 🍁fall - it’s harvest season so let’s collect all the fruits of our hard work at the bench
#thanksgivingCanada
🇨🇦
Today, we report that cholesterol-induced inflammation in adipocytes is under control of the Nfe2l1-ATF3 pathway. Proteasome-mediated proteostasis is vital to suppress insulin resistance and atherosclerosis in mice and is linked to obesity in humans.
👇
I stayed in a academia because
1. I was fortunate enough to be given the choice (luck)
2. I was supported by mentors and advocates who believed in me (network)
3. I’m extremely stubborn (perseverance & hard work)
4. It’s my dream job (Idealism)
Happy Friday
You win some, you lose some - this week grant rejected, but paper accepted!
Embracing failure, learning from it, and turning it into victory is a key asset in academia, as frustrating as it may be.
We will prevail - Happy Weekend
I’m organizing two conferences this September and I have come to the conclusion that if it doesn’t work out with tenure I want to be a wedding planner!
On this
#InternationalWomensDay
I want to testify that women are still being discriminated in science and the numbers don't lie. Projects, authorships, grants, panels, or whatever we have support
#womeninSTEM
better so that they may leverage their potential without barriers!
This month, our lab turns 5 - and what a ride it has been! I am extremely grateful to all the people who have helped building the lab baby step by baby step and making every day enjoyable! Thank you, AB ❤️
Today, we are celebrating
#WomenAndGirlsInScienceDay
. There are still so many things to be done to protect
#WomenInSTEM
from sexism, structural and conscious/unconscious bias. Let’s support them better!
Today, our 🇧🇷 🇩🇪 Workshop at the foot of the Alpes 🏔️ has ended - 2.5 days full of interaction and networking! Big thanks to the students for their scientific enthusiasm 🙏
These days, I spend many mornings with my students working on their manuscripts - sadly, my schedule doesn’t allow much of this but it’s really the best part of my job - sit down in peace and quiet, discuss, and harvest the fruits of their hard work 😃
#OTD
10 years ago we
@JoergHeeren
published my PhD work
@NatureMedicine
- became one of the highest cited
#brownfat
💩 papers ever - laid the foundation for many new lines of research, PhD theses, and papers - reproducibility is key for sustainable science
#OTD
10 years ago I defended my
#PhD
- what an exciting journey it has been - but that was just the beginning - extremely grateful for everything
#science
has given me and to my mentors
@JoergHeeren
and
@ghotamis
- All I ever wanted was to boldly go where no one has gone before🧑🔬
😢Today, we say farewell to the VERY FIRST member of
@BarteltLab
🫀 - I am beyond grateful to
@sajjad_khani
for helping me create our
#science
playground out of nothing, for being a great mentor to the younglings, and so much more🐑🔥- you will be missed - godspeed at
@CECAD_
🙋♂️
Off to the 44th
@society_eas
European Lipoprotein Club with posters and talks in our bags - excited for new science and meeting our dearly missed colleagues in person ☀️
To all tweeps, former, current, future lab members, colleagues, collaborators, reviewers, friends, and family, wherever you are, whatever you are celebrating these days, Happy Holidays, to good health and good fortune! 🙋♂️
Today marks the end of era for me. For 10 years, I was affiliated with Harvard and it brought me enormous joy and professional success. Many of my fellow postdocs during those years have become my PI peers, and remain friends with so many memories attached ❤️✊
Today, we say farewell to our technician Silvia who with her great heart, organization talents, and pipetting skills kept the lab running, had a watchful eye on the juniors, and was always there to help! We will miss you 🙋♂️
We all know that UCP1 is regulated by cold but what about coupled respiration during thermogenesis🔥?
Check out our new study on the roles of IF1 and the reverse mode of ATP synthase for bioenergetics in brown adipocytes💩
👇
Just realized that our recent paper
@nwillemsen95
et al. was my 50th peer-reviewed publication🤩! Infinitesimal step for mankind, important milestone for
@BarteltLab
🚨Attention you Bavarians! We invite scientists interested in energy metabolism & mitochondria🔥 to participate in our 🇧🇷🇩🇪 workshop this September 2024. Details below & more info to follow!
👇
We
@BarteltLab
have peer-reviewed more than 80 manuscripts this year.
I hope this pro bono effort was worth it, as we try to provide constructive criticism of methods and conclusions, simply to help make the science better and reproducible