Timothy Daly, PhD @PhilAlz Twitter profile

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Timothy Daly, PhD

8 months

Just out in Ageing Research Reviews, with @AlbertoEspay @KarlHerrup @KasperKepp our alternative to the amyloid hypothesis of Alzheimer's disease

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Timothy Daly, PhD

@PhilAlz

1 year

Lecanemab: turning point, or status quo? An ethics perspective in @Brain1878 to Hardy & @cathmummery I cite @AlbertoEspay @nvillain_alz @LonSchneiderMD @seb_walsh & argue "belief in the amyloid hypothesis continues to drive priority setting in AD research"

Lecanemab: turning point, or status quo? An ethics perspective

Hardy and Mummery1 argue in their Special Commentary that the anti-amyloid lecanemab works in Alzheimer's disease (AD), in line with Karran and De Strooper

academic.oup.com

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Timothy Daly, PhD

@PhilAlz

1 year

Against healthism in dementia prevention: Sharing responsibility @WileyHealth Over-emphasis on lifestyle in dementia prevention rests on pre-scientific "healthism" that reduces health to an individual's property & problem. @iansample @pash22 @ProfRobHoward

Against healthism in dementia prevention: Sharing responsibility

Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences.

onlinelibrary.wiley.com

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Timothy Daly, PhD

@PhilAlz

1 year

Cold Moon Journal just published my #haiku - setting sun photos of us in a drawer Thanks @beach_haiku ! Check out the journal here:

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Timothy Daly, PhD

@PhilAlz

3 years

just e-handed in my PhD thesis: Alzheimer's Disease: Epistemology, Ethics, Innovation.

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Timothy Daly, PhD

@PhilAlz

2 years

Nice surprise! "Dear Dr. Daly, I am pleased to tell you that your submission has been accepted for publication in The Lancet Healthy Longevity"

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Timothy Daly, PhD

@PhilAlz

2 years

Docteur de @Sorbonne_Univ_ !

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Timothy Daly, PhD

@PhilAlz

3 years

Dr. Daly!

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Timothy Daly, PhD

@PhilAlz

3 years

1/10 @journal_ad Reports just published results from our survey w/ @ISTAART @alzassociation #AAIC2021 . “…the optimism toward the ACH which has motivated… the recent @US_FDA decision may well not be shared by the majority of researchers working on AD"

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Timothy Daly, PhD

@PhilAlz

1 year

In @bioethics_net Neuro I cite @Gill_Livingston @seb_walsh @LenaHofbauer & argue "Dementia Prevention Guidelines Should Explicitly Mention Deprivation" to avoid narrow focus on lifestyle. For lifestyle approaches I argue, “no ought without support.” PDF:

Dementia Prevention Guidelines Should Explicitly Mention Deprivation

The brain requires sustained interaction with a rich physical and social environment to stay healthy. Individuals without access to such enabling environments and who instead live and grow in disab...

www.tandfonline.com

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Timothy Daly, PhD

@PhilAlz

2 years

In @alzdemjournals I argue that the label "preclinical AD" has limited public health value if it includes individuals who are positive for specific AD biomarkers without clinical manifestations and without certainty that they'll develop them. Thoughts?

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Timothy Daly, PhD

@PhilAlz

6 months

1/4 In @CCCBJournal see my review on "The iceberg of dementia risk: empirical and conceptual arguments in favor of structural interventions for brain health" Lifestyle is the tip of the iceberg. Below the surface of bias we find deeper contributors 👇

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Timothy Daly, PhD

@PhilAlz

3 years

I have my PhD viva defense "Alzheimer's Disease: epistemology, ethics, innovation" on the 6th of December, 2PM Paris time. It'll be in English. Please DM me if you want the Zoom link.

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Timothy Daly, PhD

@PhilAlz

1 year

My manuscript "Dementia prevention guidelines should explicitly mention deprivation" was just accepted for publication in @bioethics_net Neuroscience. If anyone is interested in reading the PDF, please let me know.

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Timothy Daly, PhD

@PhilAlz

15 days

See my ku in Modern #Haiku 55.2. Thanks to Editor Paul Miller, and @petro_ck for the pic!

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Timothy Daly, PhD

@PhilAlz

2 years

1/3 See my "Ethics, evidence, and the environment in dementia risk reduction" in @LancetLongevity in which I argue @seb_walsh et al.'s population-based approach to risk reduction provides "fertile ground for an inclusive debate around priority setting"

Ethics, evidence, and the environment in dementia risk reduction

The Comment by Sebastian Walsh and colleagues on dementia risk reduction for The Lancet Healthy Longevity makes a convincing case for a shift away from individualistic lifestyle interventions to a...

www.thelancet.com

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Timothy Daly, PhD

@PhilAlz

8 months

Inspired by @AgustinMIbanez and @erzimmer 's Comment, in @NatMentHealth Dr. @pao_buedo and I wrote a piece on "Grounding mental health in bioethics" with a focus on #mentalhealth justice, lived experience, and inclusive therapy. Fully readable PDF here:

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Timothy Daly, PhD

@PhilAlz

1 year

In Philosophy of Medicine @AlexBroadbent @JonathanJFuller I cite @GarnierCrussard @pradeu @PtitPhiSciences @y_gingras @pao_buedo & argue "Philosophers of Medicine Should Write More Letters for Medical Journals" to improve philosophy's visibility in biomed

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Timothy Daly, PhD

@PhilAlz

3 months

A reminder to look behind the headlines at the clinical risk/benefit profile of these antibodies for Alzheimer's disease, and to look beyond amyloid-reduction and lifestyle-modification as the only solutions to the public health problem of dementia.

Alzheimer’s ‘breakthrough’ stalls: why a much-hyped drug is facing approval delays

The benefits of drugs such as donanemab, aducanumab and lecanemab are proving harder to quantify than potential harms, experts say

www.theguardian.com

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Timothy Daly, PhD

@PhilAlz

1 year

My piece with @KarlHerrup and @AlbertoEspay in @bioethics_net Neuroscience is available for free access at the publisher website: We argue in favour of looking beyond the amyloid-lowering strategy for disease-modifying solutions for Alzheimer's Disease.

An Ethical Argument for Ending Human Trials of Amyloid-Lowering Therapies in Alzheimer’s Disease

Given the past two decades of over 40 failed trials of amyloid-lowering therapies in Alzheimer’s Disease (AD), many of which succeeded in lowering amyloid as designed, we present an ethical argumen...

www.tandfonline.com

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Timothy Daly, PhD

@PhilAlz

3 years

My two external examiners have given the green light for my PhD viva defense!

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Timothy Daly, PhD

@PhilAlz

5 months

Happy to see my #haiku #senryu in the Winter 23/24 edition of @WalesHaiku . Congrats to the poets and thanks to @JoeWJWoodhouse and @lover__poetic !

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Timothy Daly, PhD

@PhilAlz

2 years

See my comment on loneliness and dementia.

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Timothy Daly, PhD

@PhilAlz

2 months

We argue that "language should be prudently restrained" about mAbs in Alzheimer's to avoid overstatement and false hope. We cite @SFAckley @MariaGlymour @VincentPlanche @nvillain_alz @AlbertoEspay @KasperKepp @kathy_y_liu @seb_walsh @ProfRobHoward

(PDF) Measuring our language about anti-amyloid antibodies in Alzheimer’s disease: Technical,...

PDF | On Apr 1, 2024, Timothy Daly and others published Measuring our language about anti-amyloid antibodies in Alzheimer’s disease: Technical, theoretical, and lay language considerations | Find,...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

5 months

Happy to see my #haiku #poem in Modern Haiku 55.1 (Winter/Spring 2024). Congrats to the editors and the poets. Thanks @ChrisPeys for the pic!

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Timothy Daly, PhD

@PhilAlz

2 months

Happy to see this #monoku in Issue 12 of Seashores @HaikuSpirit . Thanks to the editors.

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Timothy Daly, PhD

@PhilAlz

1 month

I was very grateful to see my two ku in @WalesHaiku . Thank you to @JoeWJWoodhouse and @lover__poetic and congratulations for the Spring 2024 edition:

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Timothy Daly, PhD

@PhilAlz

7 months

Delighted to have four(!) of my #haiku / #senryu published in Issue 1.4 of haikuNetra, thanks to @daipayan_haiku . This selection includes my #monoku selected for The Editor's Pick. Congratulations to the editors and poets.

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Timothy Daly, PhD

@PhilAlz

2 years

my article with @KarlHerrup and @AlbertoEspay on the ethics of anti-amyloid trials in AD was just accepted in @bioethics_net Neuroscience! Please DM if you'd like to read the accepted manuscript.

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Timothy Daly, PhD

@PhilAlz

5 months

I now have my own "Poet Profile" at The Haiku Foundation @haikufound . Thanks to Marta Chocilowska and also to @beach_haiku for posting about it!

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Timothy Daly, PhD

@PhilAlz

4 months

My iceberg paper is most downloaded @CCCBJournal last 90 days. Read it to see how we might achieve fair and far-reaching dementia prevention via collective action: + gave a talk on it (in French) @Isped_Bordeaux @BPH_Research

The iceberg of dementia risk: empirical and conceptual arguments -...

Titre : The iceberg of dementia risk: empirical and conceptual arguments in favor of structural interventions for brain healthIntervenant : Timothy DALYPhilo...

www.youtube.com

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Timothy Daly, PhD

@PhilAlz

1 year

If you are a researcher or ethicist and have issues with recently published scientific research, consider writing a letter to the journal. I offer steps to writing a good letter here: @pao_buedo @kjmeetswrld @ignaciomastro @lgarciavalina @JeremyIsaacs4

(PDF) How to write a good embedded ethics letter

PDF | On Feb 14, 2023, Timothy Daly published How to write a good embedded ethics letter | Find, read and cite all the research you need on ResearchGate

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

1 year

1/5 with @AlbertoEspay & @KarlHerrup in @ELSNeurology Handb Clin Neurol Ch. 10 we argue research into neurodegeneration has not followed Popper's a priori "conjectures and refutations." Saving the amyloid hyp has meant: post hoc modifications (DM for PDF).

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Timothy Daly, PhD

@PhilAlz

20 days

Thanks to @gmomillan for this photo in which I was presenting work with @ignaciomastro at #WCB2024 in Qatar. @FLACSOARGENTINA On this slide I was addressing @G_Owen_Schaefer 's objection that "MEURI" is most usefully understood as a form of research.

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Timothy Daly, PhD

@PhilAlz

2 years

My piece w/ @ignaciomastro accepted in @TheLancetNeuro on @smead2 et al.'s first use of Prion protein monoclonal antibody (PRN100) therapy for Creutzfeldt-Jakob disease as a possible exemplary case of responsible innovation in neurology & the need for more ethical guidelines.

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Timothy Daly, PhD

@PhilAlz

2 years

In @bmj_latest I argue " #lifestyle approaches to #dementia #prevention should exist alongside broad action against the social determinants of #brain health and the rigorous testing of targeted interventions in high #risk people." Article accessible here:

The need to look beyond lifestyle in preventing dementia

I would argue for caution in interpreting the public health impact against dementia of Dhana and colleagues’ encouraging finding that older people with virtue (healthy diet, cognitive and physical...

www.bmj.com

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Timothy Daly, PhD

@PhilAlz

1 year

In @SpringerNature Neurological Sciences I describe the harms of four kinds of misuse of scientific language in neurodegeneration research: "tortured phrases," falsification, overstatement, and misleading use of causal language -> misunderstanding & waste.

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Timothy Daly, PhD

@PhilAlz

1 month

Always delighted to see a #haiku of mine in Cold Moon Journal. Thanks as always, @beach_haiku .

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Timothy Daly, PhD

@PhilAlz

2 years

Just sat down to read a novel for the first time in 2 years. Post-PhD life.

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Timothy Daly, PhD

@PhilAlz

2 months

Thank you to Bryan Rickert for including one of my #senryu and a #haibun in Issue 99 of @SenryuJournal Failed Haiku. Check out the issue here:

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Timothy Daly, PhD

@PhilAlz

2 years

As a basically anonymous graduate student for 4 years, working in a discipline whose existence is known to almost nobody outside of it, it feels strange to think I will be attending a swanky Sorbonne University PhD graduation ceremony later today!

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Timothy Daly, PhD

@PhilAlz

1 year

@adamfeuerstein @gregggonsalves @ProfRobHoward @MadhavThambiset @pash22 @a_charidimou @barttels2 @LonSchneiderMD @dmrind @AE_MD @MemoryDoc @nvillain_alz @seb_walsh @AlbertoEspay @ayton_scott @reshmagar @jasonkarlawish @KarlHerrup @GiovanniFrisoni @macesari @geoperry @samgandy @Gill_Livingston @Kariem_Ezzat @andrea_sturchio @AndaloussiLab @rkhamsi @r_merrick @DrLiHueiTsai @Jasonmmast @damiangarde @lauriemcginley2 @grace_huckins @aylinsdincer @PamBelluck @schrag_matthew @kathy_y_liu @biogen @EisaiUS @naomikresge @DrMariaALZ @alzassociation @barttels @StefanoSensi14 @KasperBJohnsen @US_FDA @KasperKepp @oncology_bg @VPrasadMDMPH For lecanemab approval to be like AZT, beta-amyloid in AD would have to be analogous to HIV in AIDS. It is not. And it's a fallacy to believe that we can start usefully combining drugs for AD before we rigourously validate them individually.

(PDF) An Argument for Simple Tests of Treatment of Alzheimer’s Disease

PDF | Two potential disease-modifying approaches for dementia are being vigorously tested: the early targeting of the neuropathology of Alzheimer's... | Find, read and cite all the research you need...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

2 years

1/4 See my "From lifestyle to stimulation for dementia prevention in Brazil" in LANAM in which I argue that "Framing dementia as a problem of stimulation (physical, mental, and social) ... invites a situation of shared responsibility for prevention"

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Timothy Daly, PhD

@PhilAlz

9 months

Grateful to see my one-line #poem in the latest and final issue #26 of Bones Journal: Thanks to Johannes S. H. Bjerg.

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Timothy Daly, PhD

@PhilAlz

1 year

@pash22 @ProfRobHoward @LonSchneiderMD @barttels2 @seb_walsh @MemoryDoc @MadhavThambiset Unfortunately, yes. They got the current problems in dementia research down to a Tea.

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Timothy Daly, PhD

@PhilAlz

2 years

In Aging Medicine I argue "Dementia outcomes will increasingly reflect inequalities unless vital action is taken against the social determinants of frailty" FYI @jasonkarlawish @SusanneRoehr @GarnierCrussard @MatthieuPiccoli @APPGLongevity @WheelerSimon

The vital need for action against the social determinants of frailty

Aging Medicine is an open access journal for international collaboration in multiple research disciplines across the aging sciences.

onlinelibrary.wiley.com

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Timothy Daly, PhD

@PhilAlz

3 years

Fascinating article: "Biomedical and psychosocial approaches continue to develop separately from each other ... Bridging this gap has the potential for progressing knowledge on preventing and delaying the dementias."

Bridging the divide between biomedical and psychosocial approaches in dementia research: the 2019...

To provide a new perspective on integrated biomedical and psychosocial dementia research. Dementia is being recognized as a multifactorial syndrome, but there is little interaction between biomedi...

www.tandfonline.com

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Timothy Daly, PhD

@PhilAlz

19 days

Happy to see these ku in folk ku Issue 3! Thanks to editor Jodie Hawthorne @KingRiverPress1 .

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Timothy Daly, PhD

@PhilAlz

2 years

1/5 with @ignaciomastro @mathieubourdenx in @journal_ad "An Argument for Simple Tests of Treatment of Alzheimer’s Disease" in which we apply @KimmelmanJ @AlexJohnLondon 's "web of information" model to AD translation. (Fully-accessible PDF in Tweet 4/5).

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Timothy Daly, PhD

@PhilAlz

2 years

to maximise their "impact and action against inequalities, lifestyle approaches to dementia should exist alongside broad action against the social determinants of brain health and the rigorous testing of targeted interventions in high risk individuals"

Beyond lifestyle for dementia prevention

www.bmj.com

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Timothy Daly, PhD

@PhilAlz

11 months

Cold Moon Journal just published my two #haiku - morning coffee... still scooping for two wet day my only visitors the raindrops Thanks @beach_haiku ! Check out the journal here:

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Timothy Daly, PhD

@PhilAlz

7 months

Happy to see my #senryu #poetry in Issue 41 of Prune Juice journal @PJSenryu : Thanks to @acheung42 @aaronmbarry PH Fischer

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Timothy Daly, PhD

@PhilAlz

5 months

Our succinct, actionable alternative to the amyloid hypothesis of Alzheimer's disease written with @AlbertoEspay @KarlHerrup & @KasperKepp is now (finally) indexed in PubMed (fully Open Access).

The proteinopenia hypothesis: Loss of Aβ42 and the onset of Alzheimer's Disease - PubMed

The dominant protein-lowering strategy in Alzheimer's Disease (AD) has failed to provide a clinically-meaningful treatment for patients. We hypothesize that the loss of functional, soluble Aβ42...

pubmed.ncbi.nlm.nih.gov

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Timothy Daly, PhD

@PhilAlz

2 years

Breaking News! @adamfeuerstein Biogen Phase 3 data from aducanumab available here FYI @AdamMBrickman @ProfRobHoward @andrealgilmore @jasonkarlawish @pash22 @dr_shibley @AlbertoEspay @AlexJohnLondon @gregggonsalves @RenegadeSynapse @CorriveauNick

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Timothy Daly, PhD

@PhilAlz

11 months

Article w/ @lgarciavalina & @pao_buedo accepted for publication in J Radiol Nurs: Socrates in the machine: the “house ethicist�� in AI for healthcare We cite @jesswhittles @McLennanStuart & describe the roles & limits of "an on-site ethics expert" PDF:

130+ million publications organized by topic on ResearchGate

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

2 years

1/2 Link to my “How Larger Society Can Give a Helping Hand to Worldwide FINGERS” in @jpreventionalz1 . 4 steps: – make lifestyle recommendations feasible – act against social determinants – avoid moralistic attitudes – design a risk-reducing society

How Larger Society Can Give a Helping Hand to Worldwide FINGERS

The Journal of Prevention of Alzheimer's Disease -

link.springer.com

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Timothy Daly, PhD

@PhilAlz

3 months

In @EJNeuroscience we studied a case reported by @RetractionWatch of 2 publications on Alzheimer's & Parkinson's disease removed by editors at a new OA journal without notice. We cite @cpiller . May interest @JohnnyFoxe @schrag_matthew @MicrobiomDigest

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Timothy Daly, PhD

@PhilAlz

4 months

See my modified one-line #haiku in Cold Moon Journal! Thanks so much to @beach_haiku .

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Timothy Daly, PhD

@PhilAlz

9 months

See my #senryu #haiku that was just published in Scarlet Dragonfly journal — lonely staring contest moon Check out the journal here:

lonely

lonelystaring contestmoon — Timothy Daly, France

scarletdragonflyjournal.wordpress.com

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Timothy Daly, PhD

@PhilAlz

7 months

Happy to see two of my #haiku #poetry published in Issue 2 of LEAF: Journal of the daily haiku

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Timothy Daly, PhD

@PhilAlz

2 years

@seb_walsh @bmj_latest I wrote a rapid response to your Editorial: "current and future patients are worse off when we don’t respect truthfulness in communication as a cornerstone of scientific and journalistic ethos. We must do better"

The need for truthfulness in dementia research

www.bmj.com

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Timothy Daly, PhD

@PhilAlz

6 months

Final version open access PDF, "The iceberg of dementia risk: empirical and conceptual arguments in favor of structural interventions for brain health," now already out in @CCCBJournal ! Rigorous reviews, speedy publication. Thx @BoaNarlon for special issue

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Timothy Daly, PhD

@PhilAlz

10 months

Cold Moon Journal just published my one line #haiku #monoku - seaside salty thoughts about childhood / Thanks @beach_haiku ! Check out the journal here:

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Timothy Daly, PhD

@PhilAlz

3 months

Thanks as always to @beach_haiku for accepting these three #monoku for publication in Cold Moon Journal. Check out the journal here:

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Timothy Daly, PhD

@PhilAlz

2 years

@KarlHerrup Dear Karl, I just invited you to this Twitter community where you should post this question IMO:

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Timothy Daly, PhD

@PhilAlz

10 months

Article w/ @lgarciavalina & @pao_buedo published in J Radiol Nurs: Socrates in the machine: the “house ethicist” in AI for healthcare we cite @jesswhittles @dwtigard @McLennanStuart @alena_buyx & describe roles & limits of an on-site ethics expert PDF

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Timothy Daly, PhD

@PhilAlz

10 months

Cold Moon Journal just published my #haiku : parents' home looking back on my past I see a light Thanks @beach_haiku ! Check out the journal here:

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Timothy Daly, PhD

@PhilAlz

1 year

@bmj_latest published my letter on @seb_walsh et al.'s editorial on lecanemab. I defend the principle of truthfulness in dementia research & communication to protect against hype and false hope. We must stay data-focused regarding treatment expectations.

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Timothy Daly, PhD

@PhilAlz

7 months

Happy to announce that a new #haiku of mine is now online at Scarlet Dragonfly Journal. Thanks to Kathleen Trocmet for selecting my work!

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Timothy Daly, PhD

@PhilAlz

3 months

Thanks as always to @beach_haiku for selecting this piece for April's Cold Moon Journal!

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Timothy Daly, PhD

@PhilAlz

1 year

My book chapter "Trials and tribulations of the amyloid hypothesis of Alzheimer's Disease" was published. I argue—broaden participation in decision making in AD research to hedge bets against harmful homogeneity. If interested in the PDF, please DM me.

Trials and tribulations of the amyloid hypothesis of Alzheimer's Disease | Request PDF

Request PDF | Trials and tribulations of the amyloid hypothesis of Alzheimer's Disease | Has amyloid accumulation in Alzheimer's disease been wrongly vilified for decades? We still do not know for...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

2 months

In the spirit of @philinbiomed , one way that philosophers can intervene in biomedical science is at the level of hypothesis, e.g. disease etiology: Interventional Philosophy in Medicine: Formulating Hypotheses I cite @pradeu as one successful example.

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Timothy Daly, PhD

@PhilAlz

5 months

@RobertAllenPoet 1 September 1939:

"1st September 1939" by W.H. Auden (read by Tom O'Bedlam)

On this day Hitler invaded Poland and WWII broke out. Thucydides was an honest historian, the originator of Political Realism which observes that the relati...

www.youtube.com

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Timothy Daly, PhD

@PhilAlz

2 years

Cool to read myself in the @bmj_latest ! "Look beyond lifestyle to society" for dementia prevention (echoing @seb_walsh et al.'s position!)

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Timothy Daly, PhD

@PhilAlz

2 months

with @AlbertoEspay @KarlHerrup @BPImbimbo @KasperKepp in @journal_ad I co-wrote the following piece: "Recalibrating the Risk-Benefit Profiles of Lecanemab and Donanemab: Scales, Immunoreactivity, and Changes in Amyloid-β42" PDF here:

(PDF) Recalibrating the Risk-Benefit Profiles of Lecanemab and Donanemab: Scales, Immunoreactivity,...

PDF | Three recent anti-amyloid-β antibody trials for Alzheimer’s disease reported similar effect sizes, used non-reactive saline as placebo, and showed... | Find, read and cite all the research you...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

2 years

For Brazilian older adults' cognitive function — schooling level universally protective — physical activity (PA) more beneficial for women ——> policy priority: remove constraints on schooling and PA for women (^safe, accessible, stimulating environments).

(PDF) The Differential Effect of Schooling and Physical Activity on Dementia in Older Women and Men...

PDF | Background: Modifiable risk factors exert crucial impact on dementia. Objective: We sought to answer the question: do two modifiable risk... | Find, read and cite all the research you need on...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

2 months

Grateful to see my #haiku in Issue 21 of tsuri-dōrō. Thanks to Editor Tony Pupello for selecting my piece. Big congratulations to featured poet Chen-ou Liu on his pieces @ericcoliu . Check out the issue here:

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Timothy Daly, PhD

@PhilAlz

3 months

I enjoyed @PopNeurosci 's comment @CCCBJournal on my "iceberg of dementia risk" paper: She cited @SFAckley @ManlyEpic @MariaGlymour @seb_walsh + May interest @CaroleDufouil @pash22 @AdamMBrickman @dr_shibley @theresluethi @Gill_Livingston @David_D_Ward

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Timothy Daly, PhD

@PhilAlz

1 year

In @alzdemjournals I argue that van Maurik et al.'s claim that amyloid PET contributes to improved outcomes in AD is fulsome use of causal language that smacks of an attempt to "market" PET scans in AD and has harmful consequences for patients and research

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Timothy Daly, PhD

@PhilAlz

4 months

See my three #haiku in today's Cold Moon Journal: Thank you kindly @beach_haiku .

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Timothy Daly, PhD

@PhilAlz

1 year

Great to see the letter format being used by the patient community @Jeanc9orf72 to address urgent issues in the ALS/FTD field in a leading scientific journal @Brain1878 . Scope for doing so in the Alzheimer's & dementia field @JongsmaKr @AndrewJEHarding @ignaciomastro & beyond!

EndTheLegacy

@End_The_Legacy

1 year

Our letter to the Editor of the journal Brain has been published online. Congrats to the authors, we look forward to continued engagement with the field.

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Timothy Daly, PhD

@PhilAlz

11 months

See my #haiku & #senryu in @WalesHaiku Summer 2023: Welsh hills the sun sets on my future here Nain’s soft hand not realising how lucky I was (*Nain = grandmother in N. Welsh, pronounced like 9). Check out the issue here: Congrats @JoeWJWoodhouse !

SUMMER 2023 | home

The Summer Edition of the Wales Haiku Journal

www.waleshaikujournal.com

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Timothy Daly, PhD

@PhilAlz

5 months

Happy to have two of my texts included in today's Five Fleas Itchy Poetry: Congrats to the poets! Thanks @beach_haiku !

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Timothy Daly, PhD

@PhilAlz

9 months

In Issue 1.2 of haikuNetra, see two of my #haiku below: Thanks to @daipayan_haiku for such a lovely issue. Check out the journal here & consider contributing:

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Timothy Daly, PhD

@PhilAlz

9 months

1/2 In @tandfonline CMRO I cite @Gill_Livingston @seb_walsh @SabrinaD_Ross @LenaHofbauer and argue "we should understand dementia risk through the lens of environmental stimulation ... from brain cells and circuits ... to whole populations" PDF: -->

(PDF) If deprivation worsens dementia outcomes, stimulation should improve them

PDF | It is still not known what causes Alzheimer’s Disease (AD). In this period of uncertainty, an emerging literature on risk factors suggests that... | Find, read and cite all the research you...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

2 years

Happy to have contributed to @thomas_nedelec 's article in @LancetDigitalH on health conditions associated with Alzheimer's disease up to 15 years before diagnosis

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Timothy Daly, PhD

@PhilAlz

1 year

In @alzdemjournals I argue @seb_walsh @IshtarGovia @ruth_peters_ @NikkiAnneWilson @kaarin_anstey @WallaceLindsay et al.'s useful "population-level approach" to dementia risk may benefit from new language: Their astute reply here:

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Timothy Daly, PhD

@PhilAlz

3 years

1/3 A fully-open link to my recent Letter in the International Journal of Geriatric Psychiatry: Giving a fairer face to urban space: Progress on the long road to dementia prevention based on @susanneroehr @ProfOrtuno @GBHI_Fellows @PsychE_and_PH survey

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Timothy Daly, PhD

@PhilAlz

1 year

I encourage researchers in #Philosophy #bioethics and #ethics to publish letters in scientific journals to engage scientists in embedded debate. @pao_buedo @lgarciavalina @ignaciomastro @AlahiBianchini @jfballenger @FGzil @_APeterson_ @emily_a_largent

(PDF) The Letter as a forum to embed ethics into the scientific literature

PDF | On Jan 28, 2023, Timothy Daly published The Letter as a forum to embed ethics into the scientific literature | Find, read and cite all the research you need on ResearchGate

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

3 years

@FeyeraBender IMO, what you describe as "lack of caring" could be your new intellectual and personal object of study, with a worthy place in your thesis, and if you can justify why you're going down new avenues (IE. get rigorous about this not caring), you'll still be able to finish the PhD.

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Timothy Daly, PhD

@PhilAlz

2 years

1/3 @CambUP_Psych see "Stimulating extended minds across the lifetime for dementia risk reduction" in which I complement @SusanneRoehr 's call for action against social determinants of brain health. PDF here:

(PDF) Stimulating extended minds across the lifetime for dementia risk reduction

PDF | We urgently need to maximize high-quality physical, mental, and social stimulation of extended minds across the lifetime for dementia prevention.... | Find, read and cite all the research you...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

1 year

In @LancetLongevity I consider what "revolution" means in Alzheimer's research, the ethics of AD biomarkers, and the need to avoid over-reliance on the amyloid-lowering strategy.

The ethics of revolution in Alzheimer's research

Gregory and colleagues argue for a “new care pathway” based on early detection of Alzheimer's disease.1 They assert that there is a “strong scientific and ethical impetus to shift focus to earlier...

www.thelancet.com

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Timothy Daly, PhD

@PhilAlz

1 year

@StefanoSensi14 @HannahFreedrich @barttels2 @pash22 @gregggonsalves @ProfRobHoward @adamfeuerstein @MadhavThambiset @a_charidimou @LonSchneiderMD @dmrind @AE_MD @MemoryDoc @nvillain_alz @seb_walsh @AlbertoEspay @ayton_scott @reshmagar @jasonkarlawish @KarlHerrup @GiovanniFrisoni @macesari @geoperry @samgandy @Gill_Livingston @Kariem_Ezzat @andrea_sturchio @AndaloussiLab @rkhamsi @r_merrick @DrLiHueiTsai @Jasonmmast @damiangarde @lauriemcginley2 @grace_huckins @aylinsdincer @PamBelluck @schrag_matthew @kathy_y_liu @biogen @EisaiUS @naomikresge @DrMariaALZ @alzassociation @barttels @KasperBJohnsen @US_FDA @KasperKepp @oncology_bg @VPrasadMDMPH IMO, "working hard" to reduce one's risk of dementia is simplistic, unfounded, and moralising. It might be useful to use such language "one-on-one" with at-risk individuals, but we should go further to a population-wide approach and fight inequalities.

The need to look beyond lifestyle in preventing dementia

I would argue for caution in interpreting the public health impact against dementia of Dhana and colleagues’ encouraging finding that older people with virtue (healthy diet, cognitive and physical...

www.bmj.com

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Timothy Daly, PhD

@PhilAlz

4 months

@pash22 @seb_walsh @LonSchneiderMD @dr_shibley @ajlees @smead2 @ProfRobHoward @MemoryDoc @MadhavThambiset @_michael_scholl @VincentPlanche @StefanoSensi14 @AlbertoEspay @EWidera @nvillain_alz @KasperKepp @Gill_Livingston @DrTFromKC @jfballenger @jasonkarlawish @JamesRuFletcher @AdamMBrickman @ManlyEpic @SFAckley @ErinMPrater @hannahkuchler @CTADconference @howard_gleckman @AmerGeriatrics @kathy_y_liu @r_merrick @nlundebjerg @NathanielChinMD @US_FDA @NICEComms @RaymondKoopmans @Kariem_Ezzat @DrBenUnderwood1 @NHSEngland @deb_cohen @LarsRaket @grinberg_t @washingtonpost @AlexJohnLondon @emily_a_largent @AliceTang_mstp @MariaGlymour @AlzheimerEurope @GiovanniFrisoni It is clearly a widespread problem. A paper I co-authored — "Against “silent” retractions in neuroscience" — in which we focus on an AD and a PD paper that were simply deleted without notice by editors at a new Open Access journal — was just accepted at @EJNeuroscience .

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Timothy Daly, PhD

@PhilAlz

4 months

My #ValentinesDay one-line #haiku was just published at @haikuniverse : I looked everywhere til you found me

Valentine’s Day Haiku (3 of 25) by Timothy Daly

I looked everywhere til you found me

haikuniverse.com

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Timothy Daly, PhD

@PhilAlz

9 months

1/2 In my Review in @journal_ad , I offer ideas about "Improving Clinical Trials of Antioxidants in Alzheimer’s Disease" I cite work by @VincentPlanche @nvillain_alz @kathy_y_liu @ProfRobHoward @AlbertoEspay @kimmelman @AlexJohnLondon @geoperry PDF:

(PDF) Improving Clinical Trials of Antioxidants in Alzheimer's Disease

PDF | Maintaining diversity in drug development in research into Alzheimer’s disease (AD) is necessary to avoid over-reliance on targeting AD... | Find, read and cite all the research you need on...

www.researchgate.net

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Timothy Daly, PhD

@PhilAlz

5 months

My mini #haibun ( #prose and #haiku #poetry ) just published at Scarlet Dragonfly Journal: Thanks to Kathleen Trocmet for selecting my work.

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Timothy Daly, PhD

@PhilAlz

9 months

Inspired by @AgustinMIbanez & @erzimmer 's Comment in which they argue that mental health can benefit from other scholarly perspectives, @pao_buedo and I wrote a short piece on "Grouding Mental Health in Bioethics" that was just accepted for publication in @NatMentHealth !

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Timothy Daly, PhD

@PhilAlz

1 year

See "Improving the value of letters in biomedicine" in Health Sciences Review. We cite @Jeanc9orf72 @gcabanac & argue for more inclusive editorial practices to increase the quality and quantity of letters. @AlexBroadbent @kjmeetswrld @ignaciomastro PDF:

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Timothy Daly, PhD

@PhilAlz

2 years

@zoophilosophy @KevinZollman My former PhD supervisor put it well: "Tim, scientists think you're a philosopher; philosophers think you're a scientist."

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