My dad died suddenly 4 years ago today. In med school I struggled with guilt, anger and grief as my CPR failed. I wasn’t sure I could or even wanted to graduate. Tomorrow is my first day of residency- I’m still not sure I can do it without him. Here’s to trying though, day by day
So excited to share my first first author original research paper! I’m so grateful for the teaching, mentorship, and laughs from
@kamarroneMD
@josephcmurray
🫁
#lcsm
A retrospective analysis of consolidation
#durvalumab
immunotherapy for KRAS-mutated stage III NSCLC found that patients with KRAS-mutated NSCLC may derive similar benefit from durvalumab as patients with non-KRAS-mutated NSCLC.
#LCSM
Learn more:
Rotations of M3 finished:
✅OBGYN
✅Surgery
✅Neurology
✅Psychiatry
✅Alpine skiing
Hard to decide which rotation I liked the most, but a vacation on the slopes might be at the top 😉 Thankful for all the growth, fun, and rest this semester, looking forward to what’s next!
Had an absolute blast in Iceland! So great to refresh before M4 with stunning views, crisp clean air, and no traffic! Trip was marred only by one flat tire and my family not understanding how cool it is that half of the places we visited were Game of Thrones filming locations 🤷🏻♂️
A trip long overdue: after 8 years, I returned to China to visit my family, sightsee, and eat too much food
1) 颐和园 2) 天坛 3) 长城 4) 正定
While it is painful not knowing if I will see my grandparents again, I’m thankful and joyful to have made some new memories together ❤️
Starting med school in the middle of the pandemic was hard. As part of student government
@HopkinsMedicine
, it's been a privilege to hear the needs of my peers and advocate loudly for change. I'm so happy to share this paper capturing some of those thoughts!
#MedEd
Hiking in Shenandoah after finishing my last core rotation of med school! Beware, Alltrails told us the hike was 7.3 miles…but we were pleasantly (unpleasantly?) surprised by 3 extra miles 🫠😂
Our study from
@HopkinsThoracic
@hopkinskimmel
out now describing how unmet physical and/or social needs are associated with lower patient-reported quality of life and higher financial toxicity. Lots of work needed to provide more comprehensive survivorship care for our patients
The unmet needs of lung cancer survivors are linked with their long-term quality of life and financial toxicity. Understanding these links is crucial for effective survivorship care.
My favorite parts of
#sitc2021
!
• Targeting both the innate and adaptive immune systems
• T cell exhaustion and new advances in CAR-T
• DDR and IO crosstalk and synergy
• Single cell approaches to understanding IO resistance and transcriptional dynamics
• Seeing my dog 🐶
A great talk by
@SmithImmunology
on the role of neoadjuvant IO in understanding the transcriptional dynamics associated with PD-1 blockade! Interested in seeing how her MANAFEST assay can be used to identify new drug targets and biomarkers associated with response to IO
#sitc2021
“IO strategies need to be the comparator arm for future trials” ~ a great talk by
@SusanScottMD
highlighting advancements and thought-provoking exciting new directions in the field
Dr.
@SusanScottMD
expertly summarizing many of the recent updates in frontline immunotherapy for
#NSCLC
. Immunotherapy is the answer in driver negative but many options - more similar than different though, within the same classes. Nice balanced discussion here.
#LCSM
So proud of my colleague and friend Mattea Miller for presenting our work in identifying survivorship needs for patients with metastatic lung cancer in the
#NACLC22
poster discussion 🎉
@HopkinsThoracic
@joyfelicianomd
#lcsm
Huge fomo from missing
#TTLC23
, but so proud of my mentee and friend Tia Cheunkarndee for her Fellows Oral Abstract award😉! Check out her talk today on osimertinib in atypical EGFR. Cheering you on from nights on IM rotation on the O🎉
@SusanScottMD
@kamarroneMD
@HopkinsThoracic
A week in the national parks to celebrate finishing all my clinical rotations of med school! Nothing to stave off the stress of match like the fear of death on Angel’s Landing ☺️
• Bryce Canyon
• Moqui Sand Caves
• Zion - Angel’s Landing
• Coral Pink Sand Dunes
Wow! So honored to hear
@gradydoctor
speak at Grand Rounds & noon conference. People always say you learn the most from patients, but Dr. Manning showed how and why patient stories have so much power. Her lessons are ones I’ll keep in mind as I finish my sub-I
@OslerResidency
☺️
Grateful and proud to have been selected as a 2021
@ASH_hematology
HONORS awardee 💉💉 beyond excited and thankful for the opportunity to grow with ASH and learn from other aspiring hematologists and researchers!
#meded
#hemetwitter
#medstudenttwitter
Didn’t fully realize how burnt out from med school I was until I stopped working/studying daily and spent the week in Tahoe with college friends. Felt good to do nothing and explore nature for a week, looking forward to aiming for more balance in M2 🎉
Just some fond memories from M3 before disappearing off the face of the planet to study for Step 2!
What a privilege to have been on the solid tumor service & the O the past 2 months. Learned so much & was so touched and humbled by my patients. Excited to sleep in now though ☺️
I am lucky to have had such strong mentorship (across 3 different time zones, no less) with this project! Such a fun team to work with, and I learned so much throughout the process 😊
Recently I thought my patient had oral candidiasis but it turns out I was actually just seeing the remnants of the goldfish crackers he had right before I interviewed him. Clearly I’m ready for my medicine sub-I starting next week 🙃
#snackthatsmilesback
🐟
As President of Medical Student Senate
@HopkinsMedicine
, it was my privilege to help welcome the newest M1s with the yearly talk “10 Things I Knew Before Starting Med School” during orientation today
#MedEd
What else would you tell your M1 self?
🧵(1/3)
Our paper studying DNA damage repair in mammalian meiosis is out now in
@eLife
🎉 This project is near and dear to me because working with
@le_kat
taught me so much about science, friendship, and growth, and I am so happy to share our four years of work 🤩
Also it's still crazy to me that we wrote this paper from two different time zones and without ever meeting in-person! I don't know how tall my co-authors are! Yet, I'm still so thankful for the support from my mentors here at Hopkins and at
@UCSFMedicine
😊😊
Our pre-proof out now in
@JTOonline
showing favorable but heterogenous responses to 1L osimertinib for uncommon EGFR mutations in NSCLC. Congrats
@tiacheunkarndee
for leading this effort identifying the need for more individualized care!
#LCSM
Done with step 1 and let me just say the thing I’m most relieved about is that I don’t feel the pathological need to do Anki while at the gym or eating dinner or walking places anymore 🫠🫠
Excited to share our review paper on clinical use of amivantamab for EGFRex20ins NSCLC just in time for updated results from CHRYSALIS this week! Thankful for the support from
@kamarrone
@AlexSpiraMDPhD
@SusanScottMD
🎉
#lcsm
“If you see something, say something” - Dr. Cynthia Dunbar on sexism in medicine at ASH-a-Palooza at
#ASH21
. Thankful to have the opportunity to hear her story and grateful to
@ASH_hematology
HONORS for supporting me in attending!
#MedStudentTwitter
💉🩸
In our case report out now in
#JTOCRR
@JTOonline
we describe two patients with NSCLC who developed concomitant hepatocellular carcinoma while on ICI therapy. S/o to Tia Cheunkarndee for leading this effort and
@kamarroneMD
for brilliant mentorship
A great talk by Dr. Christine Spencer on how host factors can influence immunotherapy and cancer outcomes and a strong reminder to see patients as humans beyond their tumors 👏👏
#sitc2021
Starting off the COVID immunobiology session of
#sitc2021
with a fantastic talk from Dr. Rafi Ahmed showing lower responses to COVID vaccines in patients with non-small cell lung cancer (NSCLC). A reminder to please get vaccinated to help protect our vulnerable patients!
#lcsm
So excited to share our paper out now in
@JNCCN
describing the survivorship needs for patients with lung cancer! Learned so much from
@joyfelicianomd
, the team
@HopkinsThoracic
, and also from each patient I interviewed for this study
#LCSM
(1/4)
No one better for the job! Incoming M1s and rising M2s
@HopkinsMedicine
are in for a treat.
@redcell_doc
cares about reaching each individual students’ unique needs, and I’ve learned so much from Dr. Naik both inside and outside the classroom. Excited for this change! 🎉
#MedEd
Technology and advances in
#MedEd
are moving at lightning speed⚡️. I couldn't be more excited to lead the OSFM (formerly GTS) course into this new era! Shout out to Hank Fessler and Charlie Wiener who led this course before me. And💕to my brilliant JHU students!
#HemeStars
Excited to share this work from our team led by
@LoehrAmanda
in the Weiss lab back in Ithaca! Looking forward to seeing more work on differentiation therapy and other alternative therapies for TGCTs and other tumors in the future 🔬🎉
#cancer
1️⃣You belong here
2️⃣You’ll have some bad days, and that’s normal
3️⃣You’re not alone, ask for help
4️⃣Long-term learning is a long-term commitment
5️⃣Find a mentor, or many! (shoutout to some of mine
@kamarroneMD
@josephcmurray
@MotherinMed
🙏)
(2/3)
Fantastic talk by Dr. Kornepati on noncanonical PDL1 functions! Really interesting to learn how PD-L1 stabilizes CHK2 and excited to see synthetic lethality between PD-L1 knockout and ATR/CHK inhibitors in vitro. Paradigm-shifting, looking forward to clinical studies!
#sitc2021
Best recharge after a month on my internal medicine sub-I is a weekend with home cooked meals, movie nights with family, and completely staged photos with Mallow ☺️
Populations at risk for greater number of needs included younger patients and patients with lower household income. It is so important to support our most vulnerable patients in all aspects of their cancer care, and I am excited to see what's next in the survivorship field! (4/4)
Congratulations to
@kamarrone
, our awesome APD, and Nina Wagner-Johnston for winning the Director's Teaching Awards. We are so lucky to work with you every day.
So true, such an important read! From serving on student government, I also have concerns about how needing to supplement lectures while balancing research, extracurriculars, and life can affect med student wellness. Students need to be included in curricular discussions
#MedEd
“It is time for…the medical education establishment to reckon with the reality that, in many respects, the parallel, student-driven curriculum has won medical students over.”
Important read for anyone in
#meded
#medstudenttwitter
Congratulations to Dr.
@kamarroneMD
on receipt of a multi-year career development award from
@LUNGevity
to study neoadjuvant immunotherapy and targeted therapy for surgical lung cancer harboring a
#kras
mutation!
Dr. Zeke Emanuel with such a thought-provoking keynote talk at
#ASCOQLTY22
, I’m wondering how we should serve our patients holistically in the context of rising costs of care and financial toxicity to patients
Spliceosome mutant leukemias are sensitive to PARPi! Excited to see further applications and study for DNA damage repair factors in cancer therapies
#ASH21
#leusm
Did COVID cause remission of an advanced cancer?
61 year old man was diagnosed with Hodgkin Lymphoma. He then developed COVID. Only got supportive care. No steroids or immunotherapy. 4 months later, cancer had mostly resolved (left image vs right) 🪢
We showed that while lung cancer survivors had significant physical needs (fatigue, sleep disturbance, etc.), emotional needs were more common with almost 80% of respondents reporting fear of recurrence and living with uncertainty (3/4)
Today we are introducing our fabulous Associate Program Director Dr.
@kamarrone
. Dr. Marrone is also a graduate of our program. She completed medical school at Drexel and her IM residency at Yale.
#FacultyThursdays
Dr. Chretien you are doing a fantastic job caring for your patients and for us students. We are all lucky to have you as our dean. Even luckier to have this 🧵normalizing being vulnerable and talking about the bad days
Recently, I had an extremely difficult week at work and experienced acute stress, the likes of which I had not experienced in a long time - culminating in crying in the car before a full work day.
Had to follow my own advice for managing acute stress. 🧵
I haven't written in a while. But I think this is becoming a real crisis and I wanted to share some thoughts.
On Mental Health and Oncology, by
@MarkRobsonMD
A fascinating Ham-Wasserman talk by Dr. Andreas Trumpp highlighting leukemic stem cell sensitivities. I learned how LSCs escape NK-cell mediated immunity, and I’m excited to see where this upcoming trial of PARPi and NK cell infusion for AML leads
#ASH21
#leusm
Glad to have attended the
@Cornell
Distinguished Lecture in Cancer Biology by
@NCIDirector
Dr. Sharpless! Great talk on the state of cancer research and on addressing disparities in cancer care. Thanks for the trainee advice, happy to be connected to my alma mater again
#gobigred
6️⃣Take care of yourself
7️⃣Your path is not going to be straight
8️⃣You’re going to make it
9️⃣Honor our profession
🔟Time flies
PS I’m most proud of the slides I made for 6️⃣ feat my favorite scene from Barbie and my greatest weaknesses: Mallow and flaming hot Cheetos 😇
(3/3)
@RWeinstein12
@SIRRFS
Congrats!! Great news 🎉 I’m lucky to learn from and with you in class, can’t wait to hear about how you lead and teach others!
#MedEd
Talk was followed by expert discussion from Dr. Sandra Demaria who posed thought-provoking directions for crosstalk between the DNA damage response and immune receptors. Loved this session, will always be excited by the DDR thanks to my time in Weiss lab
@Cornell
🔴🐻
#gobigred
!
Biopsy-proven diagnosis of HCC, and not oligoprogressive NSCLC, led to appropriate treatments for both the NSCLC and HCC in both patients. In the era of immunotherapy, these cases highlight the importance of a broad ddx and the potential for concomitant primary malignancies
#lcsm
There's so many external resources and little standardized guidance on what's important now for the match with changes to USMLE. Can be overwhelming with all the expectations and uncertainty. Hope to see more considerations for wellness as curriculum develops
@HopkinsMedicine
Conducting this study and speaking to patients is what convinced me to apply into internal medicine this cycle! I learned so much from hearing how their cancer diagnoses and treatments impacted their whole lives. Looking forward to (hopefully) more of this in intern year! (2/4)