Justine Collier @Justinec_Caulo Twitter profile

Pinned Tweet

Justine Collier

1 month

Exciting news 🤩: Our article on the impact of DNA methylation in Agrobacteriumis now out in the NAR journal.

DNA methylation by CcrM contributes to genome maintenance in the Agrobacterium tumefaciens plant...

Abstract. The cell cycle-regulated DNA methyltransferase CcrM is conserved in most Alphaproteobacteria, but its role in bacteria with complex or multicentr

academic.oup.com

2

19

52

Last Seen Profiles

@fatemegee

@WTurnerTB

@slaveslayer48

@skylonnlpinkett

@jlauwring

@BenjiMarii

@bokeplokalmalam

@antonaintshit

@germangayteen01

@_lairuilui

@kevinle_bw

@MnaomitakuNoah

@Lt_Schaffer

@pawilectura

@minipanini

@si_tya_23

@BinorRaja

@cutiepoopanda

@CalWBBall

@tissue_pasta

@bokeplokalmalam

@BinorRaja

@PodLounge

@lluiscarreras7

@yuriko274

@18371m

@BinorRaja

@boskibaniowski

@damsolitaire

@JoshuaD50349171

@HinchliffT54472

@rashdam149

@bokeplokalmalam

@xiaomiItalia

@PennywisesLover

@bokeplokalmalam

Justine Collier

@Justinec_Caulo

8 months

🧬🦠Reminder: PhD/Postdoc openings in my lab!🔬🧫Please RT.

8

144

281

Justine Collier

@Justinec_Caulo

2 months

PhD Fellowships available at our Faculty in Lausanne/Switzerland. We are a host lab in someone is interested! via @unil

Fellowships

Page Fellowships of site Doctoral School of the Faculty of Biology and Medicine hosted by the University of Lausanne

www.unil.ch

3

136

261

Justine Collier

@Justinec_Caulo

9 months

🔥Hot news to start 2024 🔥: I will soon recruit two more lab members to join my dynamic team on our beautiful campus in Lausanne, Switzerland!

2

63

232

Justine Collier

@Justinec_Caulo

2 months

🎊 🍾I am delighted to announce that I have been promoted to Associate Professor @DMF_UNIL @FBM_UNIL 🥂🎉. It would never have been possible without the fabulous contribution of my many present and former lab members or without the support of my dear colleagues: thanks to all! 🥰

22

8

102

Justine Collier

@Justinec_Caulo

10 months

Delighted to share our latest preprint! 🎉 We discovered a critical connection between DNA methylation and chromosome replication in the Agrobacterium tumefaciens plant pathogen. Fantastic work from @Mart1_100dra and @FlorianFournes .

DNA methylation by CcrM contributes to genome maintenance in the Agrobacterium tumefaciens plant...

The cell cycle-regulated DNA methyltransferase CcrM is conserved in most Alphaproteobacteria , but its role in bacteria with complex or multicentric genomes remains unexplored. Here, we compare the...

www.biorxiv.org

4

32

79

Justine Collier

@Justinec_Caulo

4 years

Delighted to announce the publication of our first DNA repair story @NAR_Open

Spatial coupling between DNA replication and mismatch repair in Caulobacter crescentus

Abstract. The DNA mismatch repair (MMR) process detects and corrects replication errors in organisms ranging from bacteria to humans. In most bacteria, it

academic.oup.com

3

21

76

Justine Collier

@Justinec_Caulo

5 years

Very honored to receive a Teaching Award from my Faculty tonight. Thanks to all PhD students and post-docs contributing to my teaching @DMF_UNIL and to all students for their enthusiasm following courses.

9

4

73

Justine Collier

@Justinec_Caulo

9 months

Very proud to announce that @Sandra_Martin defended her public PhD last Friday. 🎉🎉🎉She has been my very first lab member working on Agrobacterium tumefaciens and she made fantastic new discoveries on the impact of DNA methylation in this plant pathogen.🧬🪴👩‍🔬

3

5

45

Justine Collier

@Justinec_Caulo

6 years

Want to learn more on DNA replication control in Caulobacter? The first publication of 2019 from our lab is just out in #BiochemSocTrans :

1

13

41

Justine Collier

@Justinec_Caulo

5 years

18 Bachelor students screening 5000 Pseudomonas mutants during their Molecular Biology course @ecolebiolunil ... can't wait to see what they will find!

1

6

36

Justine Collier

@Justinec_Caulo

5 years

Our latest preprint is online! We identified a novel and conserved DnaA-related protein that promotes replication initiation during exit from stationary phase. Congrats to @AntonioFrandi from @DMF_UNIL who did most of the job.

HdaB: a novel and conserved DnaA-related protein that targets the RIDA process to stimulate...

Exquisite control of the DnaA initiator is critical to ensure that bacteria initiate chromosome replication in a cell cycle-coordinated manner. In many bacteria, the DnaA-related and replisome-asso...

www.biorxiv.org

0

14

33

Justine Collier

@Justinec_Caulo

5 years

Voice-less while closing down my lab for minimum 7 weeks. I will miss my team and colleagues @DMF_UNIL enormously but I am convinced that it is the best decision to slow down the epidemics.

3

2

35

Justine Collier

@Justinec_Caulo

6 years

Kids visiting the Department to discover microorganisms! #mysteres18 #DMF #unil

0

6

33

Justine Collier

@Justinec_Caulo

3 years

Very proud of my team @DMF_UNIL : Sandra MARTIN just obtained the BEST TALK AWARD at @Agromeeting for her very first talk at a conference! Congratulations to her and a huge thank you to @snsf_ch for funding this project throughout.

Sandra Martin

@Sandra__Martin_

3 years

Really looking forward to sharing my work at @Agromeeting in a couple of hours !

3

26

2

3

31

Justine Collier

@Justinec_Caulo

4 years

Excited to share our latest manuscript on DNA mismatch repair (MMR) in Caulobacter: we show that MMR proteins are integral components of the replisome!

Spatial coupling between DNA replication and mismatch repair in Caulobacter crescentus

The DNA mismatch repair (MMR) process detects and corrects replication errors in organisms ranging from bacteria to humans. In most bacteria, it is initiated by MutS detecting mismatches and MutL...

www.biorxiv.org

0

15

32

Justine Collier

@Justinec_Caulo

5 years

The Collier/Close primary school opened this morning. Only one (lonely) student, but he is very motivated!

1

0

31

Justine Collier

@Justinec_Caulo

6 years

Exceptional new opportunity to join our lab as a PhD student @DMF_UNIL to study Epigenetics in Alphaproteobacteria. If interested, apply on the following website before March 15th:

2

26

30

Justine Collier

@Justinec_Caulo

3 years

Great moment today, welcoming so many students back on campus @ecolebiolunil @unil . I wish you all a fantastic year!

0

2

29

Justine Collier

@Justinec_Caulo

4 years

Proud of my @ecolebiolunil @unil Bachelor students performing very well during their practical Molecular Biology course, despite very strict conditions to keep everyone as safe as possible. This week, they learned how to make PCRs, clone and transform bacteria!

3

2

29

Justine Collier

@Justinec_Caulo

7 months

While I spent my day reading a PhD thesis on DNA replication control in E. coli today, I realized that I defended my own PhD precisely 20 years ago (19th March 2004)! 🎂🎉 I am very grateful to @PhBouloc who has been a great mentor!

0

1

29

Justine Collier

@Justinec_Caulo

5 years

Is anyone (Student/Tech/Post-doc) interested to join my lab in for a short but funded 3 month-period (Sept.1st-Nov.30th) to work on bacterial toxins? Candidates MUST already be in Switzerland and should get in touch with me directly by email.

0

31

25

Justine Collier

@Justinec_Caulo

5 years

Here we are again, finding exciting connections between cell cycle progression and the metabolic status of the bacterial cell. Great work from the @ViollierPat team.

0

6

25

Justine Collier

@Justinec_Caulo

3 years

Exciting challenge to start this new academic year: I am very lucky to join a great team @ecolebiolunil @unil

1

25

Justine Collier

@Justinec_Caulo

5 years

Season's greetings from the Collier Lab!

0

1

24

Justine Collier

@Justinec_Caulo

5 years

On strike to fight against these numbers: while 56% of our PhD students are women, 81% of our Professors are men in my Faculty! Where do women disappear? #Grevedesfemmes2019

3

6

25

Justine Collier

@Justinec_Caulo

7 years

My Department will host Didier Mazel this up-coming Friday. He will give a seminar on the Architecture and the Replication of the two Vibrio chromosomes. Everyone can join (12pm at the Biophore) and I am looking forward to it!

1

4

21

Justine Collier

@Justinec_Caulo

6 years

Great success for the poster of my post-doc Antonio Frandi at the Embo DNA Replication conference in Kylini!

1

0

21

Justine Collier

@Justinec_Caulo

1 year

Congratulations to Laurent, who is now a new Doctor in the team!

2

0

20

Justine Collier

@Justinec_Caulo

6 years

Please RT: Interested in Epigenetics/Cell cycle control/Alphaproteobacteria? A PhD position is available in my lab. Fantastic Department, right by the Geneva lake! Feel free to apply:

1

49

19

Justine Collier

@Justinec_Caulo

5 years

Les écoliers du canton de Vaud à la découverte des microbes @DMF_UNIL . Merci à @saramitri pour l'organisation de cet atelier!

0

3

19

Justine Collier

@Justinec_Caulo

3 years

Almost two years ago, @ecolebiolunil lost a fantastic teacher: Tribute to Professor Stefan Kunz #mdpiviruses via @VirusesMDPI

Tribute to Professor Stefan Kunz

It has been a year since Stefan Kunz, a Full Professor since 2017 at the Faculty of Biology and Medicine of the University of Lausanne, Switzerland, passed away [...]

www.mdpi.com

0

5

17

Justine Collier

@Justinec_Caulo

3 years

Fabuleuse initiative de vulgarisation scientifique d'une post-doctorante de mon équipe @FBM_UNIL @unil pour sensibiliser le grand public à un enjeu majeur de santé publique: la résistance des bactéries aux antibiotiques.

Resist NOW 💊 Open for orders now!

@AMR_comics

3 years

We are live!! Resist NOW will be a science fiction comic about antimicrobial resistance made by 7 different science artists who work together with awesome scientists to highlight their research! Support us on @Kickstarter !

2

53

105

0

9

17

Justine Collier

@Justinec_Caulo

6 years

Could members of the Lrp family of regulators connect central metabolism with cell cycle progression in Alphaproteobacteria? Check our latest publication on that topic:

0

6

16

Justine Collier

@Justinec_Caulo

6 years

Our latest Review on the impact of DNA methylation in Alphaproteobacteria just came out for those interested to learn more on this topic!

The impact of DNA methylation in Alphaproteobacteria

Most Alphaproteobacteria encode DNA methyl-transferases (MTases) that modify adenines or/and cytosines. These usually belong to restriction/modification systems that control horizontal gene transfe...

onlinelibrary.wiley.com

0

8

15

Justine Collier

@Justinec_Caulo

2 years

Today, a new academic year begins @ecolebiolunil @unil : I wish all our students a good start and a wonderful automn semester on a lively campus!

0

1

14

Justine Collier

@Justinec_Caulo

7 years

PhD fellowships in Life Sciences available in Lausanne, Switzerland: international competition open to everyone with a Master degree!

1

25

14

Justine Collier

@Justinec_Caulo

6 years

Do not miss Tiancong Chai's poster number 15 #CellBioPro meeting to learn more on DNA mismatch repair in Caulobacter!

1

2

12

Justine Collier

@Justinec_Caulo

7 years

Cool: Caulobacter CRISPRi is now available! PubMed - NCBI

0

2

13

Justine Collier

@Justinec_Caulo

4 years

@institutpasteur Si 35% des franciliens ont deja eu la Covid-19, ne serait-il pas judicieux de faire des test serologiques systematiques avant chaque vaccination, pour optimiser l’utilisation des doses de vaccins disponibles?

1

0

12

Justine Collier

@Justinec_Caulo

5 years

Fascinating new story from the Thanbichler lab: replication and segregation of the chromosome are decoupled in the Hyphomonas neptunium bacterium:

0

5

11

Justine Collier

@Justinec_Caulo

7 years

Feeling excited to visit the @institutpasteur in Paris next week to teach a Master2 Microbiology course!

2

0

11

Justine Collier

@Justinec_Caulo

7 years

Looking forward to hosting Xavier De Bolle for a seminar on Brucella's cell cycle in our Department next Friday! Anyone is welcome!

1

3

11

Justine Collier

@Justinec_Caulo

5 years

Excited to see that the SsrA-tagging system I studied during my PhD is not the only Quality Control system at translating ribosomes in bacteria!

Cell

@CellCellPress

5 years

Online now at Cell: Alanine Tails Signal Proteolysis in Bacterial Ribosome-Associated Quality Control

1

13

37

0

3

11

Justine Collier

@Justinec_Caulo

7 years

Second messenger–mediated tactile response by a bacterial rotary motor

0

4

11

Justine Collier

@Justinec_Caulo

6 years

Two essential replicative DNA polymerases exchange dynamically during DNA replication and after replication fork arrest

0

3

10

Justine Collier

@Justinec_Caulo

4 years

Interesting new finding from the Simmons lab: m6A regulates gene expression in B. subtilis.

Methyltransferase DnmA is responsible for genome-wide N6-methyladenosine modifications at non-pal...

Abstract. The genomes of organisms from all three domains of life harbor endogenous base modifications in the form of DNA methylation. In bacterial genomes

academic.oup.com

1

2

9

Justine Collier

@Justinec_Caulo

19 days

Un vrai bonheur d'accueillir les nouveaux étudiants et de retrouver les habitués @ecolebiolunil sur notre magnifique campus @unil cette semaine! Je vous souhaite à tous une joyeuse rentrée et une superbe année académique.

0

11

Justine Collier

@Justinec_Caulo

5 years

Decades of studies on CtrA, but still so many fascinating things to disciover abiout it! Bacterial cell cycle and growth phase switch by the essential transcriptional regulator CtrA

1

0

9

Justine Collier

@Justinec_Caulo

2 years

Such sad news... We will all miss him enormously. He was a role model for so many as an amazing geneticist with such a lovely personality. We will never forget him.

Víctor de Lorenzo

@vdlorenzo_CNB

2 years

Our dear friend and colleague Joseph (Pepe) Casadesús passed away earlier today. He was a legend of Spanish microbiology, an amazing mentor of many young researchers and an inspiration for the whole community. He will be sorely missed RIP.

57

103

375

0

9

Justine Collier

@Justinec_Caulo

8 months

PS: Thanks to @NoemieMatthey for our lab logo and for illustrations in this add. I am lucky to have an artist in the lab! 🎨👩‍🎨

0

9

Justine Collier

@Justinec_Caulo

3 years

Exemplary scientific carreer:

Heidi Diggelmann, pionnière des femmes scientifiques, s’en est allée

Uni de Lausanne, ISREC, Fonds national de la recherche, elle a mené une carrière exemplaire et engagée. Heidi Diggelmann s’est éteinte à l’âge de 85 ans.

www.24heures.ch

0

4

8

Justine Collier

@Justinec_Caulo

6 years

Nearly ready to go off to this great meeting. Very happy to be invited! The Biology and Physics of Bacterial Chromosome Organisation 2018

3

0

8

Justine Collier

@Justinec_Caulo

5 years

Fascinating synthetic biology project from the Bowman lab!

Cara Boutte

@caraboutte

5 years

Trying to turn E. Coli into Caulobacter.

1

11

55

0

8

Justine Collier

@Justinec_Caulo

6 years

Rsd balances (p)ppGpp level by stimulating the hydrolase activity of SpoT during carbon source downshift in Escherichia coli

0

8

Justine Collier

@Justinec_Caulo

3 years

@GradCampusUNIL @unil @MT180ch @cuso_phd @FBM_UNIL @CVCI_Lausanne @24heuresch Félicitation à @Mart1_100dra doctorante @snsf_ch dans mon équipe, qui a conquis le grand public en présentant sa thèse en 180 secondes!

1

0

8

Justine Collier

@Justinec_Caulo

1 year

👩‍🎓👨‍🎓📚Welcome, new students @ecolebiolunil @FBM_UNIL . May this academic year be filled with unforgettable experiences. Embrace the journey, stay curious and reach for your best! 🎉

0

3

7

Justine Collier

@Justinec_Caulo

4 years

Hommage au professeur Stefan Kunz

0

3

7

Justine Collier

@Justinec_Caulo

7 years

What may be the connection between proline levels and the expression of a bacterial toxin? Look for an answer at Poster 57 from Annabelle in my lab! #LS22018

0

1

7

Justine Collier

@Justinec_Caulo

5 years

I am however in one of the Departments of the Faculty where women are the most represented: @DMF_UNIL . Lucky me!

0

1

7

Justine Collier

@Justinec_Caulo

5 years

@JWVeening @hauryliuk @sjkimlab It is exactly the same in Caulobacter: 9.6% of the mRNA are leaderless!

0

7

Justine Collier

@Justinec_Caulo

8 months

A good summary!

0

7

Justine Collier

@Justinec_Caulo

8 years

Here is our latest accepted paper, a very nice collaboration with the Elias-Arnanz lab in Spain!

1

4

6

Justine Collier

@Justinec_Caulo

9 months

2) A junior postdoc to understand how DNA methylation can influence gene expression in Agrobacterium tumefaciens:

1

2

6

Justine Collier

@Justinec_Caulo

4 years

@NoemieMatthey I can’t wait for the C letter!

0

5

Justine Collier

@Justinec_Caulo

6 years

Fellowships: via @unil

Fellowships

Page Fellowships of site Doctoral School of the Faculty of Biology and Medicine hosted by the University of Lausanne

www.unil.ch

0

8

6

Justine Collier

@Justinec_Caulo

4 years

@NoemieMatthey Quaulobacter?

1

0

6

Justine Collier

@Justinec_Caulo

1 year

Congratulations to our newly graduated Master students @ecolebiolunil ! Wishing you all a bright and successful future as you embark on this new chapter in your life. #MasterGraduate

0

6

Justine Collier

@Justinec_Caulo

7 years

Very complete review on toxin-antitoxin systems.

0

2

6

Justine Collier

@Justinec_Caulo

7 years

Mutation dynamics and fitness effects followed in single cells

0

2

5

Justine Collier

@Justinec_Caulo

7 years

@JWVeening @PLOSBiology @FrancoisTaddei Yes, beautiful: I even included this data into one of my Bachelor courses!

0

5

Justine Collier

@Justinec_Caulo

4 years

Congrats to my former PhD students Tiancong Chai and Céline Terrettaz @DMF_UNIL @UNIL !

0

5

Justine Collier

@Justinec_Caulo

6 years

@SmitsLab @DMF_UNIL And I must give credits to my post-doc Antonio Frandi who made most of the work!

0

5

Justine Collier

@Justinec_Caulo

7 months

Time to choose your Master's program for next year? Here are the ones that we offer @unil :

1

4

5

Justine Collier

@Justinec_Caulo

5 years

@HallezLab @EBiondix @sunishk @ViollierPat @WanassaB Yes: I will be there this time!!!

0

5

Justine Collier

@Justinec_Caulo

9 months

1) A PhD student to study the impact of DNA methylation/DNA restriction in Caulobacter crescentus:

1

2

4

Justine Collier

@Justinec_Caulo

6 years

@MBlokesch @JWVeening Enjoy!

0

5

Justine Collier

@Justinec_Caulo

7 years

A "must-come" event!

DMF UNIL

@DMF_UNIL

7 years

Frederic Boccard from @I2BCParisSaclay will talk about chromosome organization in E. coli and P. aeruginosa. Tuesday March 6, 11h00-12h00, room 2917.2 @DMF_UNIL @unil All welcome!

0

1

5

0

2

5

Justine Collier

@Justinec_Caulo

7 years

One more fascinating sRNA!

0

4

5

Justine Collier

@Justinec_Caulo

4 years

@WanassaB @saumya_s Torturerais-tu notre ami Caulobacter pour les fêtes???

1

0

5

Justine Collier

@Justinec_Caulo

3 years

@DMF_UNIL ... maybe this is an idea for the next “Mystères de l’UNIL”?

0

4

Justine Collier

@Justinec_Caulo

7 years

I would not dare... but it is true that I earned a very nice grant from the SNSF lately. Very grateful!

Pam Brown

@BrownlabMizzou

7 years

I had a dream that @BrunLabIU and @Justinec_Caulo were giving me granting writing advice. My subconscious may be telling me something...

2

0

7

1

0

5

Justine Collier

@Justinec_Caulo

10 months

@amazeld @FlorianFournes Yes, indeed: Gammaproteobacteria and Alphaproteobacteria both use DNA methylation to control their secondary chromosomal origins of replication, but using totally different proteins/regulatory networks. Fascinating! I should have worked on multipartite genomes earlier...

0

5

Justine Collier

@Justinec_Caulo

4 years

We show that Caulobacter connects MMR proteins to the replication machinery to repair replication errors as soon as they occur, preventing the emergence of antibiotic resistances.

2

0

4

Justine Collier

@Justinec_Caulo

3 years

@DMF_UNIL @Agromeeting @snsf_ch And many thanks to the GTF and BICC facilities at UNIL, who also made clear contributions to this work.

1

0

4

Justine Collier

@Justinec_Caulo

7 years

Great story!

Nature Reviews Microbiology

@NatureRevMicro

7 years

Lysozyme counteracts β-lactam antibiotics by promoting the emergence of L-form bacteria @CellCellPress

0

32

47

0

4

Justine Collier

@Justinec_Caulo

4 years

Still so much more to understand about the biological function of m6A in nucleic acids! One more example: N6-methyladenosine modification of HIV-1 RNA evades RIG-I-mediated sensing to suppresses type-I interferon induction in monocytic cells

N6-methyladenosine modification of HIV-1 RNA evades RIG-I-mediated sensing to suppresses type-I...

N 6-methyladenosine (m6A) is a prevalent RNA modification that plays a key role in regulating eukaryotic cellular mRNA functions. RNA m6A modification is regulated by two groups of cellular proteins,...

www.biorxiv.org

0

4

Justine Collier

@Justinec_Caulo

4 years

@GradCampusUNIL @unil Great to follow the carreer of former PhD students from @DMF_UNIL . Thanks for sharing your experience with the newer generation.

0

1

4

Justine Collier

@Justinec_Caulo

4 years

One more role for my good old PhD friend, the SsrA RNA!

0

4

Justine Collier

@Justinec_Caulo

5 years

@WanassaB @ViollierPat @sunishk @dnarepairlab You did a really great job on stage!

0

1

4

Justine Collier

@Justinec_Caulo

5 months

@MBlokesch @EvolvedBiofilm @CurrentBiology @EPFL_en Quote from Melanie: "However, my ‘Plan B’ quickly came into effect when a friend informed me about an opening for a tenure-track Assistant Professor position at EPFL in Switzerland." 🥰 The best idea I ever had!!! Now, I have my friend next door in Lausanne.

1

0

4

Justine Collier

@Justinec_Caulo

5 years

Inspiring interview of the bravest mentor I have ever met during my career! JCI’s Conversations with Giants in Medicine: Lucy Shapiro via @YouTube

JCI’s Conversations with Giants in Medicine: Lucy Shapiro

Lucy Shapiro, of Stanford University, is a renowned molecular and developmental biologist whose work has answered the fundamental questions underlying the ge...

www.youtube.com

0

1

4

Justine Collier

@Justinec_Caulo

3 years

Weird viral DNA spills secrets to biologists

0

1

3

Justine Collier

@Justinec_Caulo

10 months

@Sandra__Martin_ @BeaPy13 @ViollierPat @JWVeening @nicsalamin Bravo!!!! 🎉

0

4

Justine Collier

@Justinec_Caulo

7 years

Our Department is hosting very motivated young scientists today for the Mysteres de l'UNIL. Thanks Sara!

0

2

4

Justine Collier

@Justinec_Caulo

5 years

@MBlokesch @NoemieMatthey @ThibGSana @PseudoLab_LISM She is so talented!

0

4

Justine Collier

@Justinec_Caulo

3 years

Beautiful story on how Vibrio coordinates the replication of its two chromosomes. Congratulations to all authors!

Didier Mazel

@amazeld

3 years

Finaly out from the PGB foundry: the role of the mysterious RctB domain IV in the 2 chromosomes replication coupling. Bravo @TNiault @FlorianFournes and of course @MarieEveVal1

2

19

50

0

4

Justine Collier

@Justinec_Caulo

1 year

@goleylab @JWVeening Seems like you will soon be ready for a sabbatical in Lausanne!

1

0

4

Justine Collier

@Justinec_Caulo

5 years

@condonlab At least the walls miraculously resisted: architects were genius 8 centuries ago... and firemens are heroes today!

1

4

Justine Collier

@Justinec_Caulo

3 years

@BrunLabCaulo And thanks a lot for your great contribution to our symposium!

0

3