Registration for the SynBYSS Conference is now open. Co-organized by
@uhmanoa
and JCVI, we will unite in-person a previously online-only group, with the goal to invest in the young, diverse, and international future of synthetic biology.
@Moon_Synth_Bio
In “Evolution of a minimal cell” the authors found while genome streamlining in JCVI’s minimal cell (JCVI-syn3B) was costly, leading to a decrease in fitness of greater than 50%, this deficit was regained during 2,000 generations of evolution (300 days).
JCVI is excited to announce that several of our scientists will be contributing to the newly launched
@research_long
— a collaboration of researchers, clinicians, and patients working to rapidly study and treat
#longcovid
.
cc
@drmfreire
Twenty-one years ago today the first draft sequence of the human genome was published marking a turning point in human genomics. Six years later JCVI published the first human diploid sequence of an individual.
JCVI honors Rosalind Franklin for her invaluable contributions to modern molecular biology, including her work on DNA. Lab notes and images from her work are found in the J. Craig Venter Institute Archives, including the famous Photograph 51. Franklin would have been 98 today.
Today we celebrate
#DNADay
by showcasing two important historical items in JCVI’s History of Molecular Biology Collection. Rosalind Franklin’s Photo 51, depicting the structure of DNA and one of Francis Crick’s lab notebooks.
#NationalDNADay
Besides being stunningly beautiful,
#diatoms
are a microalgae that is responsible for a whopping 20% of global oxygen production. A better understanding of these important phytoplankton is key for healthy ocean ecosystems.
On this day in 1995, using whole-genome shotgun sequencing, a team of scientists at TIGR (a precursor to
@JCVenterInst
), published the genome of Haemophilus influenzae, the first free-living organism to be completely sequenced.
#OnThisDay
Eleven years ago today scientists from the J. Craig Venter Institute published results on successfully building a cell with a synthetic genome, a first in synthetic biology.
#synbio
#HappyBirthday
@drjcraigventer
! Your sense of adventure and wonder for this world inspires all of us. Wishing you a year full of many more discoveries and a lot of happiness.
Nineteen years ago, our Founder, CEO and Executive Chairman,
@JCVenter
and a team of scientists published the first draft sequence of the human genome in the journal,
@sciencemagazine
.
Ever wonder what happens to the human microbiome during extended periods in space? JCVI investigator Dr. Lorenzi is looking at just this to help solve the challenge of extended space flight.
25 years ago today, Drs.
@JCVenter
, Hamilton O. Smith, and a team of scientists at TIGR (now JCVI), published the first complete genome of a free-living organism, Haemophilus influenzae. Prior to that, only portions of genomes or small viral genomes had been sequenced.
On May 20, 2010, Drs.
@JCVenter
, Smith, Hutchison, Gibson, and team from JCVI announced the completion of the First Self-Replicating Bacterial Cell, M. mycoides JCVI-syn1.0.
#synbio
With support from
@diabetesrsrch
, JCVI's Dr. Suzuki demonstrated a skin bacteria could respond to blood glucose levels, produce insulin, & serve as a painless substitute for glucose sensors & insulin pumps. Because of this he's obtained an additional $1.2M in funding.
#T1D
Twenty years ago today, Dr. J. Craig Venter joined President
@BillClinton
and Dr. Francis Collins
@NIHDirector
at the White House to declare a major scientific breakthrough, the completion of the first draft sequence of the human genome.
.
@JCVenter
: “Science and sailing go together…Einstein was a sailor. It’s a way of restoring your sensibilities and bringing everything back together. You’re not using anything artificial. Wind and water and people and what they do.”
@InkyM
Today we celebrate Rosalind Franklin for her immeasurable contributions to understanding the structure of
#DNA
. JCVI Archives contain many of Franklin's original papers, including photo 51.
#InternationalWomensDay
Wishing a very happy birthday to our founder and CEO,
@JCVenter
. Cheers to many more years of countless adventures and advancing the world of science.
2000: During a White House press briefing, Celera and the
@NIH
Human Genome Project jointly announced the completion of the first draft sequence of the human genome. Pres.
@BillClinton
declared it “the most important, most wondrous map ever produced by humankind…”
#HGPub18
Scientists from the
@UofIllinois
@chemistryuiuc
, JCVI, and
@tudresden_de
have developed a computer model of the minimized synthetic cell, JCVI-syn3A, that accurately predicts the growth and molecular structure of its real-life counterpart.
Tae Seok Moon, Ph.D. (
@Moon_Synth_Bio
) and Nan Zhu, Ph.D. join J. Craig Venter Institute faculty. JCVI continues to actively recruit faculty to expand core research areas, including human health and synthetic biology.
Wishing the minimal cell another happy birthday. “Design and synthesis of a minimal bacterial genome,” was published in
@ScienceMagazine
8 years ago today. Since publication, the team at JCVI and an ever-growing, worldwide research community have utilized…
Diatoms have found a way to pirate bacterial iron sources,
@JCVenterInst
scientists use CRISPR technology to discover how.
@andreweallen
,
@scrippsocean
graduate student Tyler Coale and collaborators published a paper in PNAS
Happy Birthday to our Founder, CEO and Chairman, Dr.
@JCVenter
. His passion for adventure and drive for excellence inspires all of us. Cheers to many more years of discovery!
With emerging single cell genomic technologies leading to a rush of new data, we developed software to compare cell-type data from multiple experiments. Using
#bigdata
&
#XAI
, this knowledge can be brought into modern biomedical and life science research.
In celebration of
#NationalDogDay
, we’d like to highlight
@JCVenter
’s dog Shadow, a male standard poodle. Dr. Venter and Shadow hold something in common: they are the first of their species to have their complete genomes sequenced.
Key members of the first draft human genome team in 2001 and again at the 10 year anniversary in the presence of Archbishop Desmond Tutu who had his genome sequenced in 2010. Looking forward to another photo opportunity at the 20 year anniversary.
#HGpub18
#HumanGenome
On this day in 2007,
#JCVI
Scientists announced the groundbreaking findings of the first Sorcerer II Global Ocean Sampling Expedition (GOS) in a special issue of PLoS Biology.
Check out
@nature
article “How biologists are creating life-like cells from scratch” featuring
@JCVenterInst
scientist and leader of the JCVI Synthetic Biology group, John Glass.
Happy Birthday to our founder, Dr. J. Craig Venter! The accomplishments you continue to make year after year are nothing short of inspiring. We hope this next one is your best yet!
Thirteen years ago a team led by
@JCVenterInst
President,
@KarenKenelson
, published the first major human microbiome study, radically changing the way we look at human health and the microbes that inhabit each of us.
In a recent
@Nature
article readers are given quick history in the field of
#synbio
. JCVI’s John Glass was interviewed about the work in constructing Mycoplasma mycoides, the first self-replicating minimal cell. He discusses barriers & future applications.
The Sorcerer II Global Ocean Sampling Expedition continues this summer! The team has been sampling in the waters off New England to catalogue the microbes living in our waters and the growing problem of microplastics. Read the history of our GOS program
Since 2004,
@JCVenterInst
’s Global Ocean Sampling program has been a leader in oceanic research, focused on understanding its microbial populations. To date, we’ve discovered millions of new genes and nearly 1000 genomes for uncultivated lineages of microbes.
#WorldOceanDay
A new article by
@jsomers
@NewYorker
investigates JCVI’s groundbreaking work on the minimal cell. JCVI’s John Glass, PhD and
@JCVenter
, PhD have been at the forefront of this research for over a decade.
Har Gobind Khorana, PhD, was an Indian American and early practitioner of chemical and molecular biology. He would become an international scientific icon and a beacon of inspiration and hope for his native India.
At JCVI, we believe every child deserves access to authentic, hands-on, inquiry-based science experiences. We partner with
@leaguexse
, a SD non-profit and growing community of scientists, entomologists, biologists, oceanographers, architects, engineers, educators, and parents.
Leveraging Oxford Nanopore’s long read sequencing technology, our team was able to assemble the red seaweed genome and its unique biochemical gene clusters, along with its associated marine organisms.
@nanopore
On September 4th, 2007 a multidisciplinary JCVI team led by
@JCVenter
reached another pivotal milestone in genomic science with the publication of The Diploid Genome Sequence of an Individual Human in PLOS Biology.
Trillions of microbes call the human body home. Fourteen years ago, a team led by
@KarenKenelson
published the first major human microbiome study. Today, research is linking specific bacteria, or lack of them, with health issues like heart disease or mental health.
JCVI scientists explored 16S rRNA sequences from scalp and pubic hair microbiomes from healthy adults from multiple locations in the United States to investigate how the hair shaft micro- and macro-environment affects microbial variation.
It’s been 14 years since the remarkable discoveries of JCVI’s Global Ocean Sampling Expedition were published in a special edition of
@PLOSBiology
– Ocean Metagenomics: A collection of articles from the
@JCVenterInst
Global Ocean Sampling Expedition.
With funding from the National Institutes of Health (
@NIH
),
@JCVenterInst
scientists generated multiple Zika virus genomes in order to sequence-verify the reagents for researchers.
Happy
#DarwinDay
! Inspired by 19th century sea voyages like Darwin's on the H.M.S. Beagle, JCVI’s Sorcerer II ⛵️circumnavigated the globe for more than two years, covering a staggering 32,000 nautical miles, visiting 23 different countries and island groups on four continents.
According to
@WHO
, studies have found thousands of
#microplastic
particles in every L of drinking water.
@JCVenterInst
Chris Dupont and collaborators are investigating if these
#microplastics
are creating a new habitat for microbes to flourish.
Sequencing the first draft human genome in 2001 took approximately 300 Applied Biosystems 3700 sequencers. Today scientists can use technology that fits in the palm of their hand.
#18yearchallenge
#FlashbackFriday
Mold is Everywhere and Impacts You! Mortality rates from aspergillosis (AI) range from 30 to 95%. Learn more how the scientists at
@JCVenterInst
are developing tools to understand invasive
#Aspergillosis
diseases.
@CDCgov
#FungalWeek
.
@JCVenterInst
La Jolla campus is a featured case study in Zero Net Energy Study Buildings: Volume 3. “This case study is significant because it points the way to a performance goal that has been considered impractical, if not virtually impossible to achieve.”
Learn how JCVI researchers Yo Suzuki & John Glass are repurposing skin bacteria to serve as surrogate beta cells that can sense blood glucose levels & secrete insulin, serving as a needleless substitute for T1D treatment.
The official webpage for SynBYSS is live!
The SynBio Young Speaker Series (SynBYSS) was started as a virtual weekly seminar in Aug '21 during the COVID-19 pandemic by JCVI Professor Tae Seok Moon, Ph.D. to highlight contributions by synthetic biology postdocs and junior faculty.
Remembering former J. Craig Venter Institute Trustee Bill Walton — while many knew Bill for his accomplishments on the basketball court, we knew Bill as a larger-than-life advocate of basic scientific research.