Shelly Flagel @Flagel_Lab Twitter profile | Pikagi

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Shelly Flagel

@Flagel_Lab

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Behavioral #neuroscientist trying to better understand the #neural mechanisms underlying motivated #behavior and #addiction vulnerability. Opinions my own.

University of Michigan, Ann Arbor, MI

https://t.co/D3tt8QDkVD

Joined December 2017

Don't wanna be here? Send us removal request.

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@Flagel_Lab

Shelly Flagel

3 months

Happy to see our most recent (open access) review out online : "Leveraging Individual Differences in Cue–Reward Learning to Investigate the Psychological and Neural Basis of Shared Psychiatric Symptomatology: The Sign-Tracker/Goal-Tracker Model". 1/

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@Flagel_Lab

Shelly Flagel

4 years

Overheard my 9 yo explaining to his class what type of research I do. I just asked him what prompted that. He said, "Oh, we were playing 'would you rather' and the teacher asked 'would you rather be a mouse or a rat'...so I told them how much smarter rats are". (don't @ me)

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@Flagel_Lab

Shelly Flagel

3 years

"Neuroscience Needs Behavior"

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Neuroscience Needs Behavior: Correcting a Reductionist Bias

Krakauer et al take the view that current neuroscience places too much emphasis on techniques and causal accounts of explanation. They argue that detailed study of behavior and its algorithmic...

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@Flagel_Lab

Shelly Flagel

2 years

Hottake (after watching a rat do its thing for 45 min): Automated analyses & deep learning approaches are cool & useful, but nothing can replace experimenter observation. We in #neuroscience #behavioralneuroscience can't lose sight of this. (Don't @ me if it is too late.)

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@Flagel_Lab

Shelly Flagel

10 months

Congratulations @Huda_Akil1 ! The National Medal of Science! This recognition is so well-deserved. I still have goosebumps and a smile on my face from watching the ceremony. Thank you for all you have done for #neuroscience , @umich , and for me. ❤️💛💙

@SantaJOno

Santa Ono

10 months

Congratulations to University of Michigan’s own Huda Akil for winning the National Medal of Science today for her seminal contributions to brain biology 〽️

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@Flagel_Lab

Shelly Flagel

1 year

Lots of feels this week. A HUGE thank you to past and present @Flagel_Lab members, mentors, colleagues, and letter-writers/endorsers of my promotion package. Your contributions and support along the way mean so much to me. 1/

@Kurt_Fraser

Kurt Fraser

1 year

Congrats to @Flagel_Lab on her promotion to Full Professor! So well deserved. Happy to have been a small part of all your success, you set a great example of how to do it all.

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@Flagel_Lab

Shelly Flagel

2 years

Looking for a #postdoc to join @Flagel_Lab in our quest to uncover #neural #circuitry underlying individual differences in motivated #behavior . We use #transgenic models, #chemogenetics , #optogenetics & #deepphenotyping to probe brain-behavior relationships. Interested? Email me.

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@Flagel_Lab

Shelly Flagel

3 years

I thought I was doing ok, but I just saw my 12-year-old's response to the question, "How are you all doing with Zoom fatigue?

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@Flagel_Lab

Shelly Flagel

2 years

Not at #FENS2022 . No grant or paper to report. Nothing brilliant or provocative to say. But happy to share some #PureMichigan beauty with you (and my kids) today.

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@Flagel_Lab

Shelly Flagel

3 years

Astrocyte pond is back for the winter, but now with some medium spiny neurons and pyramidal cells. #neuronsinnature #puremichigan

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@Flagel_Lab

Shelly Flagel

3 years

I am hoping to have a new #postdoc join the @Flagel_Lab @UMich in the first half of 2022. If you are interested in studying the neural circuitry underlying individual differences in motivated #behavior , please reach out. #neuroscience #optogenetics #chemogenetics #deephenotyping

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@Flagel_Lab

Shelly Flagel

5 years

An enormous amount of thought, time and energy went into this from several wonderful (and mostly Twitterless) people, and I am thrilled to put it out “there”. 1/ The PVT is a Critical Mediator of Top-down Control of Cue-motivated Behavior

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The Paraventricular Thalamus is a Critical Mediator of Top-Down Control of Cue-Motivated Behavior

Stimuli or cues in the environment can elicit complex emotional states, and thereby maladaptive behavior, as a function of their ascribed value. Here we capture individual variation in the propensity...

www.biorxiv.org

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@Flagel_Lab

Shelly Flagel

3 years

I'm just gonna put this here...

@nytimes

The New York Times

3 years

Yakei, a female macaque in a nature reserve in Japan, violently overthrew the alpha male of her troop to become its first female leader in the reserve’s 70-year history. She presides over 677 monkeys, but a messy love triangle could endanger her status.

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@Flagel_Lab

Shelly Flagel

1 year

Looking for a #postdoc interested in #behavioral #computational #neuroscience up for a challenge: to perform in vivo Ca++ imaging in the paraventricular thalamus (PVT). Come help us figure out what this powerful little nucleus is doing and how it is influencing behavior. RT/DM

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@Flagel_Lab

Shelly Flagel

1 year

My 11-yo son was SO EXCITED to tell me that @Huda_Akil1 was featured on their middle school display for Arab American History Month. He said, "She was right up there with DJ Khaled and I told everyone she used to be your boss!" Love it on so many levels!😊

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@Flagel_Lab

Shelly Flagel

1 year

Forming a reading list for our @NIDAnews T32 fellows. Top 20 "classic" papers that shaped the #addiction #neuroscience field. Go! (Please add in comments below.)

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@Flagel_Lab

Shelly Flagel

5 years

I can finally publicly CONGRATULATE Sofia Lopez @remisofialop on her F99/K00 #DSPAN Award. This well-deserved award will support her for up to 2 years of graduate work (F99) on then into her postdoc for up to 4 years (K00). Thank you @NIH and @NINDSDiversity for this mechanism!

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@Flagel_Lab

Shelly Flagel

2 years

Today I, once again, fooled Med-PC into thinking that I understand its ridiculous programming language and know what I am doing. Been playing this game for >20 years and found great joy in the fact that some things never change. #nichetweet #behavioralneuroscience #PIWin

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@Flagel_Lab

Shelly Flagel

4 years

Happy that this story, which was a very long time coming, is finally out. Big thanks and congrats to the team: Paolo Campus, @josh_haight , @IgnacioRCovelo , @BrittanyKuhn6 , @cemariarios , Allison Johnson and @jon_d_morrow

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@Flagel_Lab

Shelly Flagel

5 years

Our paper is out in @eLife today! @IgnacioRCovelo @BrittanyKuhn6 @remisofialop @parkourmom @johnfneumaier The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior in rats Descriptive thread below.

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The paraventricular thalamus is a critical mediator of top-down control of cue-motivated behavior...

A top-down circuit generating from the prelimbic cortex and projecting to the paraventricular nucleus of the thalamus mediates individual differences in cue-elicited responding by affecting subcort...

elifesciences.org

@Flagel_Lab

Shelly Flagel

5 years

An enormous amount of thought, time and energy went into this from several wonderful (and mostly Twitterless) people, and I am thrilled to put it out “there”. 1/ The PVT is a Critical Mediator of Top-down Control of Cue-motivated Behavior

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@Flagel_Lab

Shelly Flagel

4 years

HUGE congrats to Sofia Lopez @remisofialop for turning in her dissertation today! I think there should be a special letter or symbol added to "PhD" for those who write and defend during a pandemic. PhD^C-19? Nonetheless, congrats @remisofialop , you make @Flagel_Lab proud!

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@Flagel_Lab

Shelly Flagel

6 years

Although somewhat anticlimactic in the age of bioRxiv, I am happy to announce that our paper reporting the relationship between a number of “ #addiction -related” traits came out in Scientific Reports today. Open access article: Summary thread to follow.

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@Flagel_Lab

Shelly Flagel

1 year

Happy to put this out there as more information that ChatGPT can use to describe the role of dopamine. Descriptive thread follows... Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping

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Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations...

The survival of an organism is dependent on their ability to respond to cues in the environment. Such cues can attain control over behavior as a function of the value ascribed to them. Some individ...

www.biorxiv.org

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@Flagel_Lab

Shelly Flagel

6 years

Big congratulations to @TerryERobinson1 and Kent Berridge on the Grawemeyer Award! Duo behind addiction theory win 2019 psychology Grawemeyer Award

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@Flagel_Lab

Shelly Flagel

3 years

I strongly recommend that every behavioral neuroscientist (and scientist for that matter) tracks vendor, location, and barrier room for every study you do and, when possible, include such factors in your analyses.

@samaha_lab

Dr Anne-Noel Samaha

3 years

@Kurt_Fraser @Flagel_Lab @jon_d_morrow Indeed. Scary, because who has the time to obsessively track vendors/provenance/rooms??

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@Flagel_Lab

Shelly Flagel

4 years

A little humor for my neurofriends today. Had a few favorites, but especially glad I read to the very end. 😄

The Neuroscientist, A Field Guide

How to spot a neuroscientist in the wild

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@Flagel_Lab

Shelly Flagel

1 year

On this September 1, I am no longer the Interim Co-Director of MNI & am offically a full Professor. Looking forward to the next chapter for me & our wonderful neuroscience community @umich . Thanks to @Henrypaulson5 for being a great co-Director & all other players (iykyk).

@UM_MNI

Michigan Neuroscience Institute (MNI) 〽️🧠

1 year

On September 1, we welcome MNI's new Executive Director, Ravi Allada, M.D. ( @AlladaSleep ). Dr. Allada will lead the charge to connect U-M researchers from across campus to explore the brain on a cellular, molecular, and behavioral level. @umich @umichmedicine #neuroscience 🧵

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@Flagel_Lab

Shelly Flagel

3 years

I wrote 500 words for @npp_journal to highlight the #PVT as one of the more important brain areas for emotional and behavioral regulation. "The paraventricular nucleus of the thalamus and its potential role in #psychopathology " #hottopics #neuroscience

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@Flagel_Lab

Shelly Flagel

5 months

#FluorescenceFriday I 🩷the #PVT 😍 image courtesy of @FlagelLab postdoc, @SSDesrochers

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@Flagel_Lab

Shelly Flagel

1 year

I am very much looking forward to working with @gavanm to lead @EurBehavPharm into the future. Fun fact: Gavan and I are "scientific siblings, we both did our postdoc with @Huda_Akil1 . He also happens to be one of my favorite scientists & thinkers (e.g., #EBPS2023 plenary!).

@EurBehavPharm

Eur Behav Pharm Soc.

1 year

🚨 Exciting news for the Executive Committee 🚨 Prof. Shelly Flagel ( @Flagel_Lab ) of @UMich has assumed her role as President. And our Congratulations to Prof. Gavan McNally ( @gavanm ) from @UNSW , who is President-Elect. We look forward to this next chapter for the society

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@Flagel_Lab

Shelly Flagel

9 months

Happy to have this out and featured by @SfNJournals ! "Inhibition of Dopamine Neurons Prevents Incentive Value Encoding of a Reward Cue: With Revelations from Deep Phenotyping" Led by @agiglesi & @alvinnchiu , but a team effort with many, including @helixCB & @Huda_Akil1 @UM_MNI

@SfNJournals

SfN Journals

9 months

#JNeurosci : Using #optogenetics @agiglesi @alvinnchiu @Flagel_Lab et al. @NGPMichigan confirm the necessity of dopamine neuron activity in the VTA during cue presentation to encode the incentive value of reward cues in male rats.

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@Flagel_Lab

Shelly Flagel

1 year

Beaming with pride this afternoon. Congratulations Dr. Iglesias @agiglesi ! You will be missed terribly, but can't wait for you to spread your wisdom & continue to impact the field & the next generation of scientists. Fantastic job today! 👏💛💙 Next stop #cerebellum @ucdavis .

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@Flagel_Lab

Shelly Flagel

6 years

Just putting this out there again this morning in light of the current discussion happening at #ACNP2018 on animal models of neuropsychiatric disease.

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@Flagel_Lab

Shelly Flagel

5 months

We know how important it is to investigate and better understand sex differences, but what about vendor differences? Check out our new preprint where we see effects of sex and vendor in examining the role of corticosterone on sign-tracking behavior. (descriptive thread below) 1/

@biorxivpreprint

bioRxiv

@biorxivpreprint

5 months

The effect of corticosterone on the acquisition of Pavlovian conditioned approach behavior is dependent on sex and vendor #bioRxiv

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@Flagel_Lab

Shelly Flagel

3 years

Behavioralists and non-behavioralists, my grant- and manuscript-reviewers, leaders who don't believe that behavior is actually neuroscience, all NEED to read this article. 1/

@Flagel_Lab

Shelly Flagel

3 years

"Neuroscience Needs Behavior"

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@Flagel_Lab

Shelly Flagel

3 years

I understand the disappointment & questions. But please take a minute to recognize the amount of work that goes on behind the scenes @SfNtweets - the stellar staff & your colleagues who volunteer their time. These humans are navigating this in real time, just like you. #BeKind

@SfNtweets

Society for Neuroscience (SfN)

3 years

The Society for Neuroscience will hold #SfN21 as a fully virtual experience, eliminating all in-person options that had been planned for McCormick Place in Chicago, Illinois. See our October 8 statement for more details.

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@Flagel_Lab

Shelly Flagel

2 years

A little difficult to capture its beauty on camera and behind the fence (that protects it from deer), but our little serviceberry planted in honor of @DrNadiaChaudhri bloomed today. A reminder of the strength, beauty, and resilience that Nadia shared with and taught many of us.

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@Flagel_Lab

Shelly Flagel

4 years

Congrats to @remisofialop on her 1st primary author manuscript! Open access not yet available, but, you should be able to see the abstract and figures, for now. 1/n A proposed role for glucocorticoids in mediating dopamine-dependent cue-reward learning

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A proposed role for glucocorticoids in mediating dopamine-dependent cue-reward learning

Learning to respond appropriately to one’s surrounding environment is fundamental to survival. Importantly, however, individuals vary in how they respond to cues in the environment and this variati...

www.tandfonline.com

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@Flagel_Lab

Shelly Flagel

6 years

I want to hire a #postdoc in the coming months! If you are interested in joining a fantastic and collaborative team to explore the neural circuitry underlying individual differences in motivated behaviors, contact me (sflagel @umich .edu). More info: Pls RT!

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@Flagel_Lab

Shelly Flagel

4 years

I am honored and excited to work with @Henrypaulson5 and all of our wonderful colleagues in the Michigan neuroscience community as we embark on this forward-looking journey. 1/2

@Huda_Akil1

Huda A

4 years

Thrilled and Delighted that @Henrypaulson5 will be the interim Director and @Flagel_Lab the Interim co- Director of the Michigan Neuroscience Institute! An amazing team to move the MNI vision into the future! Congratulations!

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@Flagel_Lab

Shelly Flagel

9 months

Leaving #SfN2023 with tired feet, a full heart & excitement for our field & community (at large and within @NGPMichigan @UM_MNI ). Well done @SfNtweets (and Program Committee)! And super proud of Princess Felix and Brianna Ramos. Thanks for visiting our posters!

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@Flagel_Lab

Shelly Flagel

3 years

Excited to have this out on @biorxivpreprint ! This work started with a coffee shop conversation between me and @um_psychology colleague, Ashley Gearhardt, & expanded to a collaboration with @mpwpaulus @LIBR_Tulsa , based on discussions at conferences. 1/

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The propensity to sign-track is associated with externalizing behaviour and distinct patterns of...

Externalizing behaviours in childhood often predict impulse control disorders in adulthood; however, the underlying biobehavioural risk factors are incompletely understood. In animals, the propensity...

www.biorxiv.org

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@Flagel_Lab

Shelly Flagel

3 years

Look how quickly this "autumn brilliance" serviceberry we planted in honor of @DrNadiaChaudhri has shown its beauty! 😍

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@Flagel_Lab

Shelly Flagel

3 years

Planted ( @jon_d_morrow planted, I picked it out) this "autumn brilliance" serviceberry tree today in honor of @DrNadiaChaudhri . It sits at the edge of the woods and I can't wait to watch it grow. It will nurture many creatures and provide much beauty in the years to come. ❤

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@Flagel_Lab

Shelly Flagel

3 years

A big thank you to outgoing President @lvanderschuren & Past-President @jfcryan for all you have done for @EurBehavPharm . As President-Elect, I look forward to working with @yavinshaham to make @EurBehavPharm more global, inclusive & representative of our scientific community. 1/

@EurBehavPharm

Eur Behav Pharm Soc.

3 years

Many congrats to Shelly Flagel @Flagel_Lab who is the incoming @EurBehavPharm Prez and @anandgururajan , Karen Szumlinkski and Rainer Spanagel on being nominated to the full committee! #EBPS2021

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@Flagel_Lab

Shelly Flagel

3 months

#Wellness : NIH should make text codes include personalized messages: "There is no reason for you to be checking the status of an application when study section started 1 hr ago." "Sorry, you have exceeded the recommended # of logins, try again tomorrow".

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@Flagel_Lab

Shelly Flagel

11 months

And it's now out as early release in #JNeurosci @SfNJournals . Thanks to authors and reviewers! Descriptive thread below. "Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping".

@Flagel_Lab

Shelly Flagel

1 year

Happy to put this out there as more information that ChatGPT can use to describe the role of dopamine. Descriptive thread follows... Inhibition of dopamine neurons prevents incentive value encoding of a reward cue: With revelations from deep phenotyping

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Shelly Flagel

6 years

Brittany Kuhn's first first-author paper is officially out! The PVT has different roles in sign- and goal-trackers. Inactivation of the PVT increases cue-induced reinstatement, but only in goal-trackers. Next up, circuitry.

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@Flagel_Lab

Shelly Flagel

7 months

I know it is grad student recruitment season, but I have to applaud and endorse U Minnesota and @UMNPsych #behavioral #neuroscience community. @Kurt_Fraser is the most recent faculty addition to a long list of equally awesome @UM_Biopsych @NGPMichigan alumni...1/

@Kurt_Fraser

Kurt Fraser

7 months

So excited to announce I’ll be joining the Department of Psychology at the University of Minnesota @UMNPsych as an Assistant Professor this Fall! The Fraser Lab opens in August - check us out !! A dream come true!

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@Flagel_Lab

Shelly Flagel

10 months

A few of us @Flagel_Lab will be at #SfN2023 ! Our recent publication @SfNJournals and 2 posters nicely represent our interests: the role of dopamine, "stress"/GR, and the paraventricular thalamus (PVT) in cue-reward learning & motivated behavior. Visit Sat (II28) & Tues (JJ11) PM!

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@Flagel_Lab

Shelly Flagel

1 year

How I am feeling after a 10-day stint in the field observing these white-faced capuchins with @jcbeehner . So much respect for field researchers! Can't wait to go back to the amazing Taboga Forest Reserve in Costa Rica & continue to learn from the equally amazing people there.

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@Flagel_Lab

Shelly Flagel

4 years

LOOKING FOR A POSTDOC: The "Biology of Drug Abuse" Postdoctoral Training Grant @Umich has open slots coming in summer 2020, and I would love to have a postdoc join my lab via this mechanism. If interested, please contact me. (Must be US citizen or green card holder. #notmyrule )

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Shelly Flagel

4 years

My boys were much more productive than I was during my "grant-writing time" today.

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Shelly Flagel

1 year

I am glad the pandemic taught us to broaden invites to dissertation defenses. Well done Dr. @BriannaEGeorge ! Beautiful presentation and an ubelieivable amount of work (& during the pandemic!?). ...microdialysis, FSCV, self-administration, development, sex differences - holy moly!

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@Flagel_Lab

Shelly Flagel

3 years

In case anyone wants to scroll by a new paper rather than COVID news... just out in @PsychopharmEBPS : "Investigating individual differences in #opioid -taking and opioid-seeking behavior in male rats" led by Steve Chang @ddip528 in my lab. Paper: 🧵 1/

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Shelly Flagel

10 months

Good morning (live view) #SfN2023 ! Today I am excited for Grad Fair (come visit us @NGPMichigan booth!), Princess Felix's poster (II28), Brianna Ramos's poster as a TPDA Awardee at the Early Career Poster Session, and all the awesome people I will meet along the way.

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@Flagel_Lab

Shelly Flagel

2 years

My awesome visiting undergraduate student, Daniela Pereira @dpereira1121 , made this meme for her #NSF -funded REU SIREN program @NGPMichigan and it made my day. Well done Daniela! (& Thanks for your amazing leadership and the great assignment @khri_duncan !)

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Shelly Flagel

4 years

Spike was feeling left out of #PetsofACNP at #ACNP2020 . There are so many great sessions this morning, but he decided to attend the "Life After Substance Use" study group. He is also looking forward to the discussion on animal models later this morning.

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Shelly Flagel

4 years

Today's pandemic silver lining: Getting to watch @Kurt_Fraser 's public thesis defense and hear about his awesome work in the @JanakLab dissociating the psychological and neural processes underlying the meaning and value of occassion setters. Great job @Kurt_Fraser - so proud!!!

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Shelly Flagel

1 year

Well done @ACNPorg and THANK YOU to everyone on the task force committee and council that persistently pushed and subsequently approved this. Excellent move. - signed Proud @ACNPorg Member

@ACNPorg

ACNP

1 year

Please read the recent update on ACNP Annual Meeting Location Decision-Making Webpage:

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@Flagel_Lab

Shelly Flagel

2 years

#ACNP2022 #breathe #nature #selfcare

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@Flagel_Lab

Shelly Flagel

5 years

Congrats to @remisofialop for getting her first primary author paper submitted: "A proposed role for glucocorticoids in mediating dopamine-dependent cue-reward learning." I loved revisiting the world of "stress neurobiology"...more to come from us on #glucocorticoids ...

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Shelly Flagel

3 years

Happy Hannukah to those celebrating. Wishing you love, light, and happiness. Chag sameach!

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@Flagel_Lab

Shelly Flagel

2 years

Always fun to celebrate graduation @umich #neuroscience . So proud of my three graduating honors thesis students - Hannah Davies (not pictured), Alexandra Turfe & Danielle Sharon. Big shout out to postdoc, Sara Westbrook, for her stellar mentorship.

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@Flagel_Lab

Shelly Flagel

4 years

Congrats to @remisofialop on getting another chapter of her dissertation work out there! Descriptive thread to follow. 1/ Neuroendocrine and behavioral measures of negative valence in male sign-tracker and goal-tracker rats

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Neuroendocrine and behavioral measures of negative valence in male sign-tracker and goal-tracker...

Cues, or stimuli in the environment, attain the ability to guide behavior via learned associations. As predictors, cues can elicit adaptive behavior and lead to valuable resources (e.g., food). For...

www.biorxiv.org

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@Flagel_Lab

Shelly Flagel

3 years

I am excited to share so many fantastic #postdoctoral opportunities in #neuroscience AND faculty positions @umich . Please RT this🧵. @SfNtweets @FENSorg @BlackInNeuro @sacnas #blackinneuro #blackinstem #academia #WomenInNeuro #LatinXinNeuro #QueerInNeuro #AcademicJobs 1/5

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@Flagel_Lab

Shelly Flagel

4 years

Congratulations Dr. Lopez!!! @remisofialop did an AMAZING job today with both her presentation and handling questions from her committee, which included the topic of sexual fetishism in quail. Thank you so much to those who attended virtually, so great to see you all!!! 🧠😊💙💛

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@Flagel_Lab

Shelly Flagel

8 months

Happy Holidays from the Flagel Lab. Celebrating a chaotic, productive, and fun semester. Super proud of this crew of senior lab members: experiments were done, new paradigms established, classes taught, posters presented, papers & grants submitted!

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@Flagel_Lab

Shelly Flagel

3 years

For anyone considering #neuroscience #academicjobs or #gradschool @umich in #AnnArbor , this is how we do autumn. Doesn't get much better than this. (And totally makes up for those few cold cloudy days in the winter.) #puremichigan #hikeformentalhealth #breathe #SundayReset

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@Flagel_Lab

Shelly Flagel

5 years

So cool to see this posted at a local high school! I didn't know neuroscience was a "thing" until my 2nd year of college.

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Shelly Flagel

3 years

Happy to see Amanda Iglesias's @agiglesi 1st primary author paper out in a special #PVT issue of Frontiers in Integr. Neuroscience. Check out our perspective on the role of the #PVT from a historical context & the other great articles in this issue. 1/2

Frontiers | The Paraventricular Thalamus as a Critical Node of Motivated Behavior via the Hypotha...

In this review, we highlight evidence that supports a role for the paraventricular nucleus of the thalamus (PVT) in motivated behavior. We include a neuroana...

www.frontiersin.org

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Shelly Flagel

5 years

When worlds collide. @TheErinCalipari got to watch my nephew perform at the UK halftime show today. He is the one and only boy on #thefirecrackers . Super proud of him, and they truly are amazing!

@TheErinCalipari

Dr.ErinCalipari

@TheErinCalipari

5 years

I’ve been doing this for 32 years and just now saw the most entertaining half-time show I’ve ever seen. #thefirecrackers

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Shelly Flagel

9 months

Hi! I have been attending @ACNPorg for a long time, but am especially excited for #ACNP2023 , as I get to talk about my favorite nucleus, the #PVT (Mon, 9-11); AND participate in a study group (Wed, 9-11) on brain-behavior relationships across controlled and natural settings.

@npp_journal

Neuropsychopharmacology

9 months

It's me, hi 👋 Welcome to #ACNP2023 If you'll be attending @ACNPorg , drop an introduction to help yourself & others connect 🔄 Share your name, your science, tell us if you're a first timer or regular, promote your poster/talk - whatever you'd like! 🧠 See you all soon! 😁

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Shelly Flagel

5 years

Apparently Ann Arbor squirrels don't keep kosher for Passover.

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Shelly Flagel

5 years

Congrats to everyone who got grants in this week (myself included, with hours to spare)! I am in awe of that adaptive stress-immune interaction that allows academics to prosper by keeping illnesses at bay until that exact moment eRA confirms submission via email.

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Shelly Flagel

17 days

Happy that this manuscript - "The effect of corticosterone on the acquisition of Pavlovian conditioned approach behavior in rats is dependent on sex and vendor" - is now out in Hormones and Behavior. Open access article here... and summary 🧵 below...

@Flagel_Lab

Shelly Flagel

5 months

We know how important it is to investigate and better understand sex differences, but what about vendor differences? Check out our new preprint where we see effects of sex and vendor in examining the role of corticosterone on sign-tracking behavior. (descriptive thread below) 1/

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Shelly Flagel

5 years

Well-done @Flagel_Lab crew! So proud of and thankful for all of you. And, thank you to those who stopped by and offered valuable feedback. Grateful for this wonderful community we have. #sfn2019

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Shelly Flagel

3 years

I touched a rat, pipette, dry ice, and a centrifuge today; and converted four out of six meetings from zoom to in-person. So it was a good day. Now let's see how angry my email is about its neglect.

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@Flagel_Lab

Shelly Flagel

3 years

Interested in getting a #PhD in #neuroscience ? Come learn about the University of Michigan Neuroscience Graduate Program @NGPMichigan . Virtual open houses Nov. 1st & 4th, 6:30 - 8 EDT. Students & faculty will be there to answer questions. Register here:

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Shelly Flagel

3 years

Planted ( @jon_d_morrow planted, I picked it out) this "autumn brilliance" serviceberry tree today in honor of @DrNadiaChaudhri . It sits at the edge of the woods and I can't wait to watch it grow. It will nurture many creatures and provide much beauty in the years to come. ❤

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Shelly Flagel

6 years

Personal tweet, couldn't resist: My son is reading a book about about the human body and tonight declared, "I want to read about the the nervous system because I get nervous a lot." Then this...

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Shelly Flagel

6 years

"If you are reading this with judgement, educate yourself about this disease...it is not a choice, or a weakness." A poignant and beautiful obituary; and reminder of the importance of our work. #addiction

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Shelly Flagel

5 years

I spy an astrocyte on ice. #nature #beauty #sunshine #AnnArbor

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Shelly Flagel

10 months

Flagel Lab (past & present). Grateful for the scientific contributions and awesome lab culture the original crew established that is maintained with the current crew! So great to see everyone at the @NGPMichigan @UM_MNI event at #SfN2023 ! 💛💙

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Shelly Flagel

3 months

Windows in our "new" lab space will be great, but I am going to miss our basement lab wall of joy.

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Shelly Flagel

3 years

Thanks @SfNJournals for giving us the opportunity to publish these important "negative results". We had a great experience with #eNeuro ! Thread describing the results and implications is embedded below. And congrats again to @remisofialop !

@SfNJournals

SfN Journals

3 years

#eNeuro Negative Results: @remisofialop @Flagel_Lab et al. show that sign-tracker & goal-tracker rats, characterized by response to reward-associated stimuli, do not differ in behavioral or peripheral corticosterone response to stress-related paradigms.

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Shelly Flagel

5 years

Big congrats to @Flagel_Lab graduate student Amanda Iglesias @_amandaalovee on her NSF Graduate Research Fellowship! I never considered myself worthy of NSF in grad school, which makes me even more proud to have my 2nd NSF GRFPer in the lab. #NSFGRFP2019

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Shelly Flagel

3 years

Excited that some of Dr. Sofia Lopez's @remisofialop dissertation research is now out in #eNeuro as an early release article. 🧵👇🏼 1/ Male goal-tracker and sign-tracker rats do not differ in neuroendocrine or behavioral measures of stress-reactivity

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Shelly Flagel

3 years

So nice to be with (most of) the fully-vaccinated Flagel Lab crew, all together, in person, outside, with no masks. Celebrating the victories we can hold on to from this past year. #thankful

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Shelly Flagel

3 years

Thrilled to get this manuscript by @BrittanyKuhn6 et al. out in @PsychopharmEBPS . 1/ Inhibition of a cortico-thalamic circuit attenuates cue-induced reinstatement of drug-seeking behavior in "relapse …

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Inhibition of a cortico-thalamic circuit attenuates cue-induced reinstatement of drug-seeking...

These results highlight an important role for the PrL-PVT pathway in vulnerability to relapse that is consequent to individual differences in the propensity to attribute incentive salience to...

pubmed.ncbi.nlm.nih.gov

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Shelly Flagel

5 years

The dedication and service Klaus Miczek and Trevor Robbins have given to the journal (and the field!) Psychopharmacology is truly remarkable. Check out this 60th year tribute. Proud this is the journal of #EBPS @EurBehavPharm !

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Shelly Flagel

3 years

Truly a pioneer. Ed will be greatly missed. Seeing him raise his hand or stand up to ask a question at a local seminar or international meeting always made me smile, as I knew he would start with accolades for the speaker and follow with a fantastic thought-provoking question.

@jenkins_paul

Paul Jenkins

3 years

Michigan Pharmacology and the science world in general has lost a titan. Ed Domino, a pioneer of psychopharmacology, active faculty member since 1953, first to introduce ketamine in humans has passed away.

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Shelly Flagel

4 years

Oh look, a preprint from the @Flagel_Lab 3 days before R01 is due. We did some old school lesions and pharmacology to determine that the lateral hypothalamus and orexin signalling in the PVT is important for the attribution of incentive value to reward cues. 1/(see thread)

@biorxiv_neursci

bioRxiv Neuroscience

@biorxiv_neursci

4 years

The lateral hypothalamus and orexinergic transmission in the paraventricular thalamus promote the attribution of incentive salience ... #biorxiv_neursci

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Shelly Flagel

5 years

An Editorial I wrote with @NIMHDirector and @mpwpaulus : Includes highlights from discussions at the #EBPSWorkshop2018 as well as articles featured in the upcoming Psychopharmacology Special Issue - Computational and Translational Psychopharmacology.

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Shelly Flagel

2 years

It's not a holiday unless your -80 crashes. Thanks for helping me celebrate Thermo Fisher.

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Shelly Flagel

6 years

Huge congrats to Dr. Brittany Kuhn who nailed her thesis presentation and oral defense today. I couldn't be more proud!!! @NGPMichigan1 @umichgradschool #superproudmentor

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Shelly Flagel

2 years

Having my talk described as "banger" may just be the best compliment I have received in my career. Thanks @hayfish24 😉and to the VERY impressive group @PittPsychiatry for all of the stimulating discussions today! (I miss days devoted to talking science and really needed this.)

@HayleyFisherPhD

Hayley Fisher

@HayleyFisherPhD

2 years

Beautiful talk from @Flagel_Lab walking through her lab's comprehensive look into sign-tracking and goal-tracking behavior in rats and kids! You know it's a banger talk when Pavlov is mentioned throughout the talk and the thalamus (PVT) gets a nice spotlight 🧠

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Shelly Flagel

1 year

Hey #BlackInNeuroCareers #BINW23 , Want to do a #postdoc in a supportive environment & learn just how cool behavior is & expand your toolbox to include chemo- & opto- genetics, Ca2+ imaging, & computational work? All surrounding THE best nucleus (i.e. the PVT). Reach out!

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Shelly Flagel

5 years

Our current thoughts on: Mapping sign- and goal-tracking onto human behaviors. I have learned a lot from our interdisciplinary team - thanks to Janna Colaizzi, @mpwpaulus & @um_psychology colleagues, Michelle Joyner & Ashley Gearhardt. Stay tuned...

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Shelly Flagel

3 months

Review for @PsychopharmEBPS . When you click the "agree to review" link a PDF of the manuscript is automatically dowloaded AND they send you a calendar invite for when the review is due. Every journal should do this for reviewers.

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