Every palliative care thread 🧵 I’ve ever done in one place. Just click on the box below and you will find them in the replies section- updated every month ⭐️
I am a palliative care doctor. I had COVID prior to any vaccinations, it genuinely scared me how unwell I was. I’m triple vaccinated now to protect myself and those I look after. I follow the science carefully to inform my choices and it is clear that
#GetVaccinated
saves lives
Steroids in palliative care: A thread
When we say steroids it normally refers to corticosteroids such as prednisolone and dexamethasone.
Steroids are widely used in oncology and palliative care.
Let’s take a closer look at some of their uses.
Cheyne Stokes respiration at end of life- Thread
Can be scary to witness for family, loved ones and health care professionals looking on.
Understanding a little about what is happening may help alleviate some of that distress 🧵
Palliative care pearls 🛡
Please add your own and share:
“Carry a pocket torch and look at you patient’s mouth regularly: mouth care is a vital but often overlooked aspect of comfort and dignity.”
Syringe drivers: A palliative care thread
Let’s cover a topic that can be very emotive and frequently misrepresented
Administration of medications via continuous subcutaneous infusion (CSCI)
First lets cover some common concerns we may encounter when considering using a CSCI
Palliative care: Opioids 🧵
Alfentanil and Fentanyl belong to the Phenylpiperidine family and have a much higher affinity for Mu opioid receptors than Morphine and Oxycodone which belong to the Phenanthrene class.
They are more potent but this difference has other implications
Analgesia: a quick thread
(Mostly for fun)
Paracetamol: old faithful and only surviving analine analgesic. Mild pain and pyrexia. Beware low body weight and pill burden esp in severe pain.
Malignant bowel obstruction: A palliative thread
Possibly one of the most complex and challenging presentations in palliative care.
Eating, drinking and going to the toilet are habits of a lifetime.
Obstruction can lead to sudden medicalisation of what comes naturally.
Breathlessness: A palliative care thread
“Breathe deeply, until sweet air extinguishes the burn of fear in your lungs and every breath is a beautiful refusal to become anything less than infinite” – D. Antoinette Foy
Pancreatic cancer:
Palliative care reflections
A thread 🧵
Difficult to manage on so many levels.
My mum died from this condition and I was very grateful that she had the support of palliative care at home, in hospital and eventually the hospice.
Some things I’ve learned 👇
Patients with oral cancer can find oramorph causes stinging due to the alcohol content.
A switch to oxycodone oral solution can help reduce this dose related pain
Palliative care tip for Friday
Trying to explain the multiple dimensions of pain/suffering to someone can be overwhelming for all involved.
This diagram based on Dame Cicely Saunder’s work has proven really useful to help people see beyond the physical aspects of pain
Always ask about opioid timings in palliative care
Immediate release morphine and Oxycodone take at least 20-30minutes to have any effect on pain in most people. Effects last from 2-4hours.
If someone describes this pattern then their pain is convincingly responsive (in part at
Malignant Spinal Cord Compression (MSCC)- A Thread 🧵
Old fashioned medical tools of history and clinical examination are the key
Trust your instincts with this diagnosis
@nandwics
Avoiding under or over investigation for undifferentiated abdominal pain is surely one of the most difficult skills going imo. Knowledge of obs/gyn, urology, gastro, infection, surgery, vascular, paeds, endocrine, pharmacology all factor. Bad example
Benzodiazepines: A palliative care thread
As a group the benzodiazepines are one of the most commonly used medications in palliative care.
Although they can be helpful to relieve many symptoms, their evidence base is small and patient selection is key.
Let’s explore further
Managing bleeding in palliative care
A Thread 🧵
One of the most difficult topics to discuss. Bleeding reminds us all of our own fragility and elicits an immediate response from all who witness this.
Lets’s start with bleeding from local areas
Palliative care practice vs evidence
Current evidence shows that Anti-secretory medications no better than placebo at reducing noisy breathinf at end of life
So why do we continue to use them?
Absolutely delighted to have accepted a future consultant post at
@StColumbas
hospice care.
Really excited to be working alongside such fantastic, caring colleagues and to be part of the wider
@lothian_nhs
palliative care team.
Fever and Fentanyl patches don’t mix well. Increased absorption due to increased local blood flow to the skin can lead to toxicity and respiratory depression.
Particularly risky in those with cyclical pyrexia secondary to underlying malignancy.
Opioid rotation - A Thread 🧵
All opioids work the same right?
Well not really. Let’s take a closer look at how rotating from one opioid to another may produce different results
One of the most powerful ways to improve outcomes in palliative care must be continuity of contact with the same person/team.
Just my observation ✋
Not always possible but if there is a good relationship and trust then it may make more difference than any medications
Anti-depressant discontinuation
A thread 📝
Think carefully before de-prescribing anti-depressants. A very unpleasant syndrome can occur if stopped abruptly, including towards end of life.
A few things to consider
Ketamine in palliative care
A Thread 🧵
An interesting drug that divides opinion in palliative care.
Let’s have a look at how it works and when it might have a role
We need a better approach to delivering 7 day a week palliative care/end of life for those at home than the current model.
Early hours of Saturday and Sunday morning are fragile periods often leading to avoidable acute admission and distress
Time to fund 7 day Palliative care
I hope this may be a helpful thread to help reduce some of the distress surrounding this area
Normalising talking about dying as a wider society is important but we must never forget the uniqueness of everyone’s experiences and personal loss involved
Delighted to find out I have been awarded the Ilora Finlay medal by
@cardiffuni
for my MSc dissertation in palliative medicine.
Baroness
@IloraFinlay
is a wonderful advocate for palliative care
@EM_RESUS
Death bed phenomenon.
The difference between this and delirium/opioid toxicity is that the familiar visions are comforting and do not cause distress.
Experienced across cultures and often in the last hours of life, although sometimes longer.
@Medic_Russell
@DrLindaDykes
Was once asked this as an opener by a senior, I replied with “Fy2.... can I ask you how old you are?” “30” was the response. “So am I, so lets talk to each other like 30 year olds” and we did. How do we learn if unable to interact with those higher up the hierarchy?
Head and Neck cancer: A palliative care thread
When people ask “What is the definition of SPECIALIST palliative care?”
Well, I hope after reading this thread that question will be answered
One the best things about community palliative care is the reminder it gives you of the challenges that everyone faces day to day. Patients, families, friends, carers, district nurses, GPs, AHPs, ANPs, pharmacists, CNS teams, community nurses. Everyone is vital
Head and Neck cancer: A palliative care thread
When people ask
“What is the definition of SPECIALIST palliative care?”
Well, I hope after reading this thread that question will be answered
Helped out with some bystander CPR a few weeks ago. Seeing the person walking their wee dog tonight was really nice. The ambulance crew were fantastic, I don’t think we give paramedics enough praise for what they do
Community palliative care logistics
It’s Friday afternoon around 3pm
Newly referred patient requires a syringe driver with 3 medications to manage pain and nausea due to loss of oral route
Pall care CNS phones GP to ask for a prescription and for a drug chart to be written
Myeloma and palliative care - A thread
Myeloma is type of cancer that effects mature B-lymphocyte cells known as plasma cells
These cells normally produce antibodies that help fight infection.
In myeloma these cells are overproduced and lead to high levels of antibodies
Itch: A palliative care thread
As with Nausea and Vomiting the best approach is to identify the underlying cause if possible. Treatment can be targeted to best improve symptoms and reduce side-effects
Start with a good history as always
Autonomic dysreflexia: quick thread
An important condition to be aware of and be prepared for in any patient with a spinal cord injury or malignant compression at the level of T6 or above
The thing I admire most about really good GPs is there ability to accept and sit with certain levels of risk in a management approach
It’s an incredibly difficult skill and often misunderstood.
Palliative tip for Wednesday
Deprescribing towards end of life
Polypharmacy in the last year of life is common. The study below showed that an average of 10.7 medications were prescribed at the time of participants dying
Palliative care tip for Sunday
De-medicalise your patient encounters and you might learn more about what is driving their symptoms.
Don’t go straight to asking about pain or constipation or the patient may automatically focus on this next time.
Ask about what matters to them
Constipation- A quick thread
Often overlooked, not deliberately but if we don’t ask we will never know. First step in management is to take a good history
Had a colleague mention my recent threads on palliative care today and how they found them helpful. (Blush)
It was really nice as I’ve missed face to face teaching over the past year, great to know we can still pass somethings on via twitter
Drug name fun
Sinemet= without vomiting
Nystatin = New York State Institute
EMLA = Eutectic mixture of local anaesthetic
Vicodin = 6 times more potent than codeine
Warfarin = Wisconsin Alumni Research Foundation + coumARIN
Tacrolimus = Tsukuba Macrolide Immunosuppressant
Palliative pharmacological points of debate that come up weekly
-NSAIDs in cancer bone pain
-clonazepam in neuropathic pain
-ketamine
-methadone
-topical opioids
-tapentadol
-paracetamol
-lidocaine plasters
-steroids
-octreotide
-nystatin
-cannabis
#backtoscience
Palliative care tip
Bedsheets can become surprisingly heavy towards end of life.
Keep them loose and light if possible.
Weighty sheets can cause painful plantar strain on ankle tendons, reduced chest expansion and transfer weight onto vulnerable pressure areas
Uncontrolled distress in someone who is dying should be seen as an emergency
-Training to improve recognition
-Initial general measures to manage
-Escalation with clear flowchart/numbers
-Real time management and ongoing review
-Communication is the cornerstone
-Debrief
So i'm doing something I have wanted to do for many years- I have started a blog.
There are some experiences I'd like to share that I hope might help others and I have an interest in writing so why not eh?
You'll find it at
3 years ago we shared our last Mother’s day as a family
2 months later we shared our last moments together
Tell your mum how much you love her tomorrow no matter where she may be. Always in our hearts 💙