Exercise is a drug!
- Exercise is one of the most potent interventions we have to improve health and reduce risk of cancer, heart disease, metabolic syndrome and neurodegenerative disease.
- Exerkines are compounds released within our body in response to exercise that signal
CARDIO TRAINING can literally extend your life! 🏃♂️❤️
- 40% lower risk of 9 common cancers
- 39% lower risk of type 2 diabetes
- 25% lower risk of dying from heart disease
Combine CARDIO with STRENGTH training for a 41% lower risk of all-cause mortality and potentially add up to
Our mitochondria may be detecting and adapting to our mood:
- A new study involving 450 older adults, collected detailed information during their last 20 years of life and analysed their brains after they died.
- They found that increased wellbeing was linked with greater
Reduced muscle mass can cause cognitive impairment.🧠
Protect your brain by lifting some weights.🏋️♂️
- Using data from 450,243 UK Biobank participants, a Mendelian randomisation study found a bidirectional relation between sarcopenia (loss of muscle mass) and cognitive
30 minutes of exercise boosts our cancer-killing white blood cells:
- A group of 20 breast cancer patients used a stationary bike for 30 minutes at their preferred resistance and blood samples were taken before, during and after.
- During exercise, the number of
How to grow new brain cells! 🧠✨
Just 1.5 grams of omega-3 can boost brain development by increasing BDNF levels.
This vital protein supports brain cell growth, enhancing learning and memory. It also helps with appetite control, blood sugar regulation, and even protects
Strength training does this… 💪
Meeting physical activity guidelines (150 mins of moderate or 75 mins of vigorous exercise/week) can add 3-4 years to your life. But adding strength training twice a week gives even more benefits:
- 30-45% reduced risk of all-cause mortality
-
Melatonin is not just a ‘sleep’ hormone, it can impact many measures of our health, including our stem cells:
- Melatonin improved cell survival and restored mitochondrial function following exposure to oxidative stress.
- The use of N-acetyl-cysteine (NAC) significantly
Melatonin is a powerful antioxidant that reduces inflammation, slows aging, and fights cancer.
It’s vital for brain health, preserving mitochondrial function to prevent Alzheimer’s and other neurodegenerative conditions.
Boost your melatonin naturally:
- Avoid bright lights
Did you know 7 hours of sleep a night is linked with the highest biological age?
A 9-year study of nearly 14,000 people found that both too little and too much sleep can reduce biological age.
Interestingly, exercise benefits can reduce the risk for those who sleep longer but
Optimising our blood glucose levels over time, has a big impact on our longevity.
New research has found that a variety of herbs and spices associated with the Mediterranean diet have powerful effects on the glycaemic profile of patients with type 2 diabetes:
- Black cumin,
Melatonin: A preventative strategy for neurodegenerative disease (ND)?
- A recent review highlighted the multifacted effects of melatonin on ND’s, with a particular focus on its mitochondrial impact.
- Melatonin can scavenge free radicals, activate other antioxidant systems,
Worried about blood sugar levels? You need to know this!
Our muscles are the biggest glucose sink we have.
1kg of muscle can store 15-25g of sugar!💪
This makes a huge impact when you consider the difference between a diabetics blood sugar compared with a non-diabetic can be
Trying to reduce inflammation, blood glucose and cholesterol?
Eating lentils everyday has the potential to improve these biomarkers, all of which are known to be linked with longevity.
- Over a 12-week period, 38 adults underwent a dietary intervention that included 7 prepared
3 Vitamin D Mistakes🌞
1️⃣ Not taking Vitamin D3 in the morning to avoid disturbing your sleep cycle and melatonin.
2️⃣ Not taking it with a meal that includes fat for better absorption.
3️⃣ Not combining it with Vitamin K2 and magnesium for optimal health, as they work
📷
N-acetyl cysteine (NAC) is one of my favorite supplements.
1. It boosts glutathione, one of our body's master antioxidant.
2. It protects the liver and brain, reducing inflammation, and boosting fertility in both men and women.
3. It is linked to longevity in a range of
Ever notice brain fog after sitting for too long? 🧠
A study found that doing just 1 minute of half-squats every 20 minutes during prolonged sitting boosts cognitive abilities, improves concentration, and reduces mental fatigue—plus, it brings a ton of metabolic benefits!
Gut health – a key contributor to our longevity:
- Our gut microbiome plays an essential role in many aspects of our health, from enhancing our immune system, producing health-promoting metabolites, signalling to the brain and even contributes towards muscle mass.
- An
Apple cider vinegar (ACV) has the power to improve body composition, decrease body weight and improve metabolic health:
- A 12 week study of 120 young, obese or overweight participants (aged 12-25) tested the effects of 3 daily doses of ACV.
- The ACV consumption reduced BMI,
Omega-3s offer benefits similar to pharmaceutical drugs but with fewer side effects.
Taking 2g daily [EPA + DHA] can boost your omega-3 index from 4% to 8%, potentially adding 5 years to your life expectancy.
2g/day also helps reduce blood lipid levels, supporting heart health.
Did you know that Olive Oil could help protect you against Alzheimer's?
Extra-virgin olive oil (EVOO) contains more than a hundred phenolic compounds, many of which are known to reduce the likelihood of developing Alzheimer’s disease (AD):
- They can disrupt aggregation of
Sleep deprivation has a range of damaging health impacts, but creatine might at least help alleviate some of the cognitive problems it causes:
- 15 participants in a study were kept awake overnight and had to complete cognitive tasks.
- They were given either 0.35g/kg creatine
A 4x greater risk of death! ⚠️
People with the lowest vitamin D levels have a 4 times higher risk of death compared to those with the highest.
Vitamin D is crucial for our health, with deficiencies linked to cancer, cardiovascular disease, and metabolic syndrome.
Studies
Vitamin D may help protect the heart and aid blood sugar control.🫀📉
Even more so if you are older than 50 or of non-Western ethnicity:
- A review involving data from 17.656 participants found that supplementing with vitamin D was linked with beneficial effects on
Heart attacks, diabetes, obesity, hypertension and metabolic syndrome are all linked to disrupted circadian rhythm:
- Stress, artificial lights, sleep deprivation, shift work, illness and pain can all lead to these disruptions.
- Exposure to sunlight or intense daylight
High intensity interval training (HIIT) might have the power to actually reverse neurodegeneration in people suffering from Parkinson’s disease:
- Over 6 months, 13 participants took part in 72 x HIIT classes, comprised of 2 x 15 minute circuits and 15 mins of boxing. This had a
Low levels of magnesium are linked with increased DNA damage and elevated homocysteine:
- A study of 172 healthy adults found that low levels of magnesium were associated with increases in different markers of DNA damage.
- Low levels of magnesium were also associated with high
Why you should stop eating 3 hours before bed:
1️⃣ Melatonin inhibits insulin production, so a late-night meal = elevated blood glucose.
2️⃣ It takes ~5 hours to fully digest food. You can't enter "repair mode" while sleeping if your body is still digesting.
3️⃣ It benefits
Just 5 minutes of stair climbing each day or 2.6 hours standing per day has been associated with improving cardiometabolic health:
- A meta-analysis involving 12,095 adults examined the effect of daily activity levels on cardiometabolic health (BMI, waist circumference,
Better than bleach for removing pesticides!
Scientists found that baking soda is a simple, affordable solution for eliminating up to 96% of toxic pesticides from fruits and veggies.
A 2017 study showed that a 1% baking soda and water solution is even more effective than bleach
Moderate physical activity can increase cognitive performance, possibly as a result of the increased dopamine that is released during exercise:
- Training at 35% VO2peak for 25 mins lead to improvements in reaction time to a cognitive task.
- PET scans were used to show
Taking just an extra 20-30 minutes to fall asleep can have some serious effects.
This is known as long sleep latency and can reduce the function of our mitochondria, the specialised part of our cells responsible for producing our energy.
When they don’t work properly, we age
Stress depletes these 3 vital nutrients!
When you're stressed, it's not just about diet; the stress itself depletes:
Magnesium: Essential for sleep, muscle movement, and glucose metabolism.
Zinc: Key for skin health, immunity, smell, testosterone, and mood.
Vitamin B1:
A compound found in coffee, fenugreek and naturally produced in our body, can boost NAD+ levels, improve muscle health and mitochondrial function:
- Levels of trigonelline in our serum positively correlate with muscle strength and mitochondrial function in muscle.
- It also
Heavy strength training is like compounding interest for our health:
- This study looked at the effects of just 1 year of either heavy, resistance training, body weight training or no additional training in people who had recently retired.
- Both the exercise groups trained 3
Exercise grows brain cells!
- Lactate get produced during intense exercise
- This signals to the brain to make BDNF
- BDNF improves the growth and survival of existing brain cells encouraging them to form new connections
- It also stimulates the development of new brain cells
-
Want to boost your focus, lift your mood, and decrease stress?
Get out into the sun after you wake up!
It not only boosts your energy but also improves your sleep. Morning sunlight regulates your circadian rhythm, preparing your mind and body for the day and night ahead.
Accelerated aging, inflammation, mood disturbances, sleep issues, reproductive health, and cancer—all linked to reduced melatonin production. 📉
Just 2 hours of blue light exposure from screens can inhibit melatonin.
You can turn on night mode on your device or use
We know that ultra-processed foods (UPFs) have a negative impact on our health, but new research has shown that higher exposure to UPFs is linked with an increased risk for 32 negative health outcomes:
- An umbrella review of 45 existing meta-analyses found that higher UPF
Fluctuating blood sugar levels can harm your health, leading to diabetes, heart problems, and Alzheimer’s.
But you can control it with a simple trick: exercise after eating!
- For healthy people: 15 mins of brisk walking 15 mins after eating.
- For diabetics: 15-30 mins of
Ultra processed foods are putting our kids health at risk:
- A study involving 1,426 children aged 3-6 over a 3-year period found a significant link between consumption of ultra processed foods and negative health markers.
- The children with the highest UPF consumption had
In a recent study, microplastics were found in 100% of placentas tested:
- In 62 placenta samples, the levels of microplastics ranged from 6.5-790mcg per gram of tissue.
- It’s currently unclear what the health impact of these levels may be, but the half-life of these plastics
Over 1.12 million person-years, 34,247 deaths and 276,132 total participants, 8 lifestyle factors were each shown to be significantly associated with risk of death.
Lack of physical activity had the biggest effect:
- People who adopted all low risk lifestyle measures at the
If you’re looking to improve your memory and brain function as you age, weight lifting or resistance training has been shown to do just that.
Greatest benefits appear to be over 16 weeks, with a couple of session each week at moderate intensity – 50-70% of 1 rep max.
PMID:
Optimising mitochondrial health is the key to longevity.
A new paper identifies some supplements which could be beneficial:
- Interventions targeting mitochondria can help mitigate age-related declines in many aspects of our health, including sarcopenia and physical function.
Ultra-processed foods are linked to early death, cancer, heart disease, and depression. Here's how to avoid them:
1. Long ingredient lists = more processed.
2. Avoid added sugars (e.g., high-fructose corn syrup).
3. Steer clear of artificial additives (colours, flavours, E
Red light therapy can lower blood sugar levels and help prevent glucose spikes after a meal:
- Red light at 670nm is known to increase energy production within mitochondria. In a group of 30 healthy adults, 15 minutes of red-light exposure increased cellular glucose consumption.
Dental health plays a big role in our longevity:
- A recent study found a connection between periodontitis (an inflammatory mouth disease) and risk of stroke.
- This was in younger people (aged 20-50) and the severity of the periodontitis increased the risk of stroke.
- It is
Restoring our gut microbial balance and regulating the microbiome-gut-brain axis can elevate our mood and even treat depression:
- Psychobiotics are probiotic bacteria that have been suggested as a treatment for depression.
- They can boost mental health by improving the gut
Resveratrol has recently shown promise to help protect against Alzheimer’s disease:
- In a series of cell culture experiments, designed to model Alzheimer’s disease, resveratrol was found to inhibit pro-inflammatory mediators.
- It also increased the expression of antioxidant
HIIT kills senescent ‘zombie’ cells.
But it needs inflammation too:
- 912 men were put through a high intensity training sessions on a stationary bike, 20 seconds at high intensity followed by 20 seconds of rest, for 15 rounds.
- Half were given the anti-inflammatory drug
How to reverse 20 years of heart aging:
Sedentary 50-year-olds followed a vigorous-intensity exercise protocol for 2 years
By 6 months, they were doing 4-5 hours/week including 2 interval sessions, 1 long (at least an hour) and one 30-minute base pace session each week
Melatonin does far more than help us sleep.
Protecting us against Alzheimer’s is another of its potential roles:
- It may help reduce the build-up of amyloid-β, enhance its clearance and protect against its toxicity.
- The ability to counteract tau pathology – the second
Are you eating yoghurt for its probiotic benefits?
Try adding some honey:
- A recent study found that adding 21g of honey to 170g yoghurt led to a greater survival of its beneficial bacteria.
- This was compared with standard sugar too, but honey produced the best results.
-
Did you know you could be growing new brain cells with just a couple of Brazil nuts a day? 🧠✨
Brazil nuts are a fantastic source of selenium, which promotes neurogenesis—especially in the brain areas responsible for learning and memory.
Selenium also plays a key role in
Looking for a good longevity-boosting supplement?
You may have one already in your spice cupboard - Ginger:
- A comprehensive review outlined the favourable, biological effects of ginger and its extracts against each of the 12 established hallmarks of aging.
- In particular,
A natural compound found in pomegranates, strawberries, cherries and walnuts may help treat Alzheimer's disease:
- Urolithin A, a compound produced by our gut bacteria when we consume ellagic acid (found in those foods above) has been studied for a range of anti-aging effects.
Could chronic stress be increasing our risk of cancer spreading?
Persistent stress and chronic activation of the sympathetic nervous system are known to be associated with negative impacts on our longevity, but a new study, albeit in mice, has identified a possible causal role
Muscle strengthening activities, like resistance and weight training, lower rates of chronic disease and death by any cause.
Surprisingly, an optimal benefit can be achieved in just 30-60 minutes a week, but going over 140 minutes a week might be counterproductive.
Mixing
Over 4,895,544 human years’ worth of data across 884 randomised controlled trials were studied to determine the effect of 27 different micronutrients on cardiovascular risk factors and clinical events:
- The meta-analysis involved 883,627 participants.
- Moderate to high
Splitting our time between cardio and resistance exercise may have a bigger impact on our health than either one alone:
- Over 1 year, 406 participants did 1 hour of exercise, 3 times a week (with a control group who did no exercise) of either resistance, aerobic or mixed 50:50
More evidence has been found showing that eggs do not have an adverse effect on cardiovascular health:
- A small study of 140 participants at high risk of cardiovascular disease and with one prior cardiovascular event studied the effects over 4 months of eating 12 or more
This is as risky as smoking! 🚬😱
Did you know that having a low VO2 max (bottom 25%) presents similar mortality risks as diabetes, obesity, cardiovascular disease, and even smoking?
You can improve your VO2 max with a mix of steady-state low-intensity exercise (like brisk
Don’t make this vitamin D mistake!
Vitamin D is vital for our health, in fact there is a 4 times greater risk of mortality if you have blood levels at the lower end of the scale.
However, excess vitamin D consumption can increase your risk of calcium being deposited in your
How to reduce your visits to the doctor by 42%?
Meditation can reduce your blood pressure, LDL cholesterol, and cortisol and help you to combat stress better.
Within just 8 weeks, people that practised for 3 hours a week were able to decrease their use of medical services by
Smelling peppermint could give you an extra 2 push-ups at maximum effort or shave nearly 3 seconds off a 400m run:
- A recent review of the power of smells on athletic performance found these interesting benefits for peppermint. It also increased cardiovascular capacity and
Want to avoid fine lines and wrinkles?
Cut out excess sugar and toasted or fried foods! 🚫🍩🍟
Excess sugar in your bloodstream creates collagen-damaging molecules called AGEs (advanced glycation end products). These bind and tangle collagen fibres, reducing their
Want to limit skin aging?
100g of baby carrots a day might help:
- Over a 4 week period, those who ate 100g baby carrots for 3 days in each week had a 10.8% increase in their skin carotenoid levels.
- Those who ate the carrots and had a daily, beta-carotene containing
Eat more mushrooms, lower your cancer risk! 🍄
A study of nearly 20,000 people found that those who ate around 20g of mushrooms daily had a massive 45% lower risk of developing cancer!
Boost your health with this simple dietary addition. 🥗✨
PMID: 33724299
#HealthTips
Added sugar = increased aging
- Using the GrimAge2 epigenetic clock, a study investigated the relationship between added sugar, essential nutrients and epigenetic age in 342 middle-aged women.
- Each gram of added sugar consumed was linked with an increase in epigenetic age.
-
Did you know that garlic has the power to reduce blood sugar levels and improve cholesterol status?
- A recent meta-analysis studied 29 trials including 1,567 participants testing the effects of garlic on different parameters of health.
- Garlic was found to be effective in
Coffee is one of the world’s favorite drinks. However, there are many common uncertainties around its use.
A recent review paper analysed 14 of these issues and came up with the following answers:
Does caffeine dehydrate you at rest?
Moderate caffeine intake doesn’t
We know that exercise can help improve mood and reduce depression, but new research has shed light on some of the best types of exercise:
- Jogging, yoga and strength training were particularly effective, though mixed aerobic exercise, tai chi and qigong still provided a
Having regular breaks throughout the day to do some very brief exercises may be one of the most optimal ways to use exercise to help control blood sugar:
- Sitting for long periods at a time has a range or negative health impacts, and our exposure to elevated blood sugar also
Eating more flavanols has a big impact on our health:
- A 36% reduction in all-cause mortality
- A 55% reduction in cancer-specific mortality
- A 33% reduction in cardiovascular-specific mortality
This is likely related to their anti-inflammatory, anti-tumour and antioxidant
Does a small amount of evening exercise disrupt sleep?
This was the question being tested in a recent study, with interesting results:
- Using a group of 30 healthy adults researchers tested the effects of 3 minutes of resistance exercises, every 30 minutes in the 4 hours
We may eat the equivalent of a credit cards weight of microplastics each week…
- Worse, babies fed formula milk from a plastic bottle may consume millions of nanoparticles a day.
- They have been found in our artery walls where they give us a 4 times greater risk of heart
Accelerated aging, inflammation, mood disturbances, sleep issues, reproductive health, and cancer—all linked to reduced melatonin production. 📉
Just 2 hours of blue light exposure from screens can inhibit melatonin.
Turn on night mode or use blue-blocking glasses to help
The sleep and activity levels of 92,221 participants were studied over 2.5 years and followed up 7 years later during which time there had been 3080 deaths:
- Both short and long sleep (exceeding a daily 6-8 hour window) were associated with an increase in all cause mortality,
Mental wellbeing = healthier aging:
- In an analysis of over 2.3 million people, those with better wellbeing tend to experience healthier aging (characterised by health, resilience and longevity).
- Reducing sedentary behaviour by watching less TV played a role in the impact of
Optimising bone health, is a key factor in longevity, particularly important for women during menopause where there is an increased risk of osteoporosis.
Surprisingly, the humble blackcurrant might hold the key to protecting bone mass:
- This study investigated the effects of a
People who achieve the physical activity guidelines live on average 3-4 years longer.
This is 150 minutes a week of moderate intensity exercise or 75 minutes of vigorous exercise.
However, adding strength or resistance training into the mix, twice a week gives additional
Do you add bananas to your smoothies?
New research suggests that you might want to reconsider this, if you’re aiming to optimise their health benefits:
-Flavanols are bioactive compounds in fruits and vegetables linked with a range of positive health benefits.
- However,
71% of us are likely to due from one of the big 4 chronic diseases.
A recent study investigated how micro and nanoplastics contribute towards this risk?
- We are exposed to these plastic fragments in so many areas of our environment.
- We know they cause physiological
Grip strength is a strong indicator of physical function as we age and has been shown to be a strong predictor of our risk of death.
Interestingly, a new study has found a link between our gut microbiome and grip strength:
- Those with a weaker grip strength were found to have
Strawberries are the worst offender… 🍓
Harmful 'forever chemicals' (PFAS) have been found in many common fruits and veggies, with strawberries being the most contaminated—over 95% of samples!
Other offenders include grapes, cherries, spinach, and tomatoes.
Used in
Gratitude is linked with a lower risk of premature death!
- A study of nearly 50,000 women with an average age of 79 completed a gratitude test in 2016.
- 3 years later, more than 4,600 had passed away but it was found that those who had the highest levels of gratitude had a
Anger can damage your blood vessels and raise blood pressure, increasing heart attack risk by rupturing arterial plaques. 😡💔
Combat this by practicing deep breathing and staying grounded in your body, not your mind. Breathe in, stay calm, and protect your heart!
PMID:
Did you know leafy greens may boost your HRV?
While fruit, fish, and other healthy foods don't appear to significantly influence HRV, those who eat lots of leafy greens—like spinach, mustard greens, and lettuce may have healthier HRV scores.
Activate your parasympathetic
You might not know that while intermittent fasting is great for blood sugar and insulin resistance, early eating patterns have the best effect on metabolic health.
Start eating earlier in the day and finish around midday for optimal results.
PMID: 38625630
PMID: 29754952
Aldehydes are associated with premature aging – common sources include heated vegetable oil, alcohol, pollution and cosmetics:
- Aldehydes are harmful because they are very reactive with DNA and protein, forming links between them that block important cellular processes, causing
How do we live longer? 🕰️
The gold standard in animals is calorie restriction, and the CALERIE study in humans showed a 12% calorie reduction led to big health improvements and slowed aging markers.
It’s tough to sustain though and has potentially negative impacts on lean body
Kaempferol’s anti-cancer potential against triple-negative breast cancer:
- A recent review summarised the existing evidence of kaempferol's anti-cancer effects.
- These include; inducing DNA damage and apoptosis, modifying ROS production, inhibiting immune evasion and limiting
Struggling with poor sleep quality?
5-HTP could help:
- A 12-week clinical trial of 30 older adults found that 100mg 5-HTP improved certain sleep quality markers, particularly in those with poor sleep.
- This could have been related to the increase in serotonin that it causes,
Have you had your daily dose of olive oil? 🫒✨
Just 10ml of olive oil a day is linked to an 8% reduced risk of death and heart disease!
I love adding a quality, organic extra virgin olive oil to my diet—it's packed with polyphenols that fight inflammation and free radicals.
It's been 50 years since the discovery that melatonin inhibits cancer in mice:
- Exposing rodents to round-the-clock lighting, suppresses night time production of melatonin and STIMULATES tumour development
- Melatonin has been shown to have beneficial effects in humans,
Memory loss and cognitive decline are a risk of obesity and insulin resistance.
But, intermittent fasting (IF) might help protect us:
- A study of 40 obese people with insulin resistance tested the effect of an IF diet (5 days healthy, normal calorie diet, 2 days ¼ usual