Aleksander Krag Profile Banner
Aleksander Krag Profile
Aleksander Krag

@AleksanderKrag

2,368
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408
Following
236
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1,282
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Professor of Hepatology @SUND_SDU @OUHhospital Director Odense Liver Research Centre @FLASH_OUH Secretary General EASL the Home of Hepatology @EASLnews

Odense, Danmark
Joined April 2021
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@AleksanderKrag
Aleksander Krag
2 years
Which diet is superior in #NAFLD and #T2D ?   Our RCT with 165 T2D pt’s in @AnnalsofIM High Fat Diet (50-60 E% fat) superior to Low Carb in   👉 improving glycemic control and insulin resistance 👉 inducing weight loss 👉 more improved ≥ 1 in NAS score
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@AleksanderKrag
Aleksander Krag
2 years
New insights in The Therapeutic Window of #betablockers and #carvedilol in cirrhosis   👉We ⚖️ ratios of risk/benefit, signal to noise and effect sizes ➡️ Window opens with presence of varices. ✅ Still need to scope if TE>20Kpa or platelets count <150.
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@AleksanderKrag
Aleksander Krag
11 months
LiverRisk score published @TheLancet @Liver_Screen ➡️ low vs high HR=471 for liver related mortality 😳 Next generation first line liver fibrosis test?🤔 👉Diagnostic AUC 0.83 vs FIB4 0.68 👉Prognostic (liver related outcomes) AUC 0.90 vs FIB4 0.84
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@AleksanderKrag
Aleksander Krag
7 months
The future of the Hepatology is here 👉EASL AASLD masterclass in Madrid ❤️ 👉Talent from US meeting talent from Europe 🤓 👉Help shape the path for next generation of liver leaders in the field is the incarnation of what EASL stands for ! @EASLnews @EASLedu @AASLDtweets
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@AleksanderKrag
Aleksander Krag
1 year
Which is a superior referral pathway for fatty liver disease? How to ⬇️false positives   3378 people Fib4 vs ELF vs NFS   👉FIB-4 38% eligible for referral 👉Reduced to 14% by ELF alone 👉FIB-4 + ELF reduce to 11% 👉88% correct classified @JHepatology
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@AleksanderKrag
Aleksander Krag
1 year
Creating public awareness of fatty liver disease is not so easy. Today I was lucky and the liver got the front page and two full pages in the National newspaper @EkstraBladet 🙏 👉knowledge is our most powerful weapon against #NAFLD #Nash 👉let’s drive change together
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@AleksanderKrag
Aleksander Krag
1 year
Interested in #NASH ?   👉Time to forget NAFLD & MAFLD? @marurinella 👉EASL-Lancet commission @tomhemmingk 👉To screen? @MajaThiele 👉What to do? @HannesHagstrom 👉The future Stephen Harrison                                              Nordic NASH F2F / online FREE sign up⬇️
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@AleksanderKrag
Aleksander Krag
9 months
Non invasive assessment of hepatic decompensation- how to do that? See suggestions in @HEP_Journal Joint publication from @LiverGALAXY @MicrobPredict @Liver_Screen @LiverHope_h2020
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@AleksanderKrag
Aleksander Krag
6 months
Screening for fibrosis promote life-style changes   4,796 at risk of ALD or MASLD- 6 months and 2 years 👉ALD excessive drinking decreased from 46% to 32% 👉MASLD 35% diet ⬆️, 22% exercised⬆️, 13% weight loss ≥5% 👉impact partly lasted after 2 years 🔓
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@AleksanderKrag
Aleksander Krag
1 year
Cardiometabolic riskfactors are important in #ALD -and #MetALD 👉2 minutes exercise twice a day reduces cardiovascular risk 🤔 @Camilla_Dalby protects us with 2 minutes exercise at @EASLedu School of Hepatology in #Odense
@AleksanderKrag
Aleksander Krag
1 year
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@AleksanderKrag
Aleksander Krag
4 months
The #SLD nomenclature in context from #NAFLD to #MAFLD to #MASLD in @NatureMedicine with @marurinella important and meaningful? 👉clinical approach to the combined role of alcohol and metabolic dysfunction. 👉How to manage liver and CV risk
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@AleksanderKrag
Aleksander Krag
4 months
Using liver stiffness to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver disease Check out👉- Journal of Hepatology 👉How to use and interpret repeated Fibroscan @KHThorhauge @GeorgSemmler
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@AleksanderKrag
Aleksander Krag
1 year
Last day of #EASLCongress 😀😓 woke up as new EASL SG -can’t feel the difference :-) Has been wonderful days 👉lots of learnings, interactions, 👉enjoy the last day 👉 don’t miss the symposium around the new nomenclatural 9.55 See you out there 😀
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@AleksanderKrag
Aleksander Krag
1 year
World liver day TODAY! Fight stigma, Shame ❌ 👉 barriers⬇️ 👉awareness and liver health ⬆️ We need NAFLD in the WHO action plan for NCD’s Liver diseases into policy makers agenda now❗️ Liver communities stand united💪 @EASLnews @alehlatam @AASLDtweets @APASLnews @JVLazarus
@WorldLiverDay
World Liver Day
1 year
🙌 Today, April 19 is World Liver Day: a bridge between population health needs and policy makers' actions. By raising awareness we can create a healthier world for all. ⭐ Join us in supporting #WorldLiverDay ! 🔗
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@AleksanderKrag
Aleksander Krag
1 year
Can Rifaximin prevent progression of alcohol related fibrosis?   👉Maybe! 👉Less progression & Inflammation⬇️   ➡️ 18 months RCT 136 pts @LiverGALAXY compliance👍   📣PoC of RCT’s in early ALD    Want to join us for more studies in early ALD/mixed NAFLD?
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@AleksanderKrag
Aleksander Krag
3 years
My first Executive meeting as EASL Vice Secretary General. We celebrate JHEP’s new IF of 25😳 Where is EASL moving? Member benefits ⬆️, new CPG’s in pipeline, ILC 2022 London F2F- can’t wait. Proud to join an amazing team @ThomasBerg24 @EASLnews @EASLedu
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@AleksanderKrag
Aleksander Krag
1 year
EASL it’s going mobile🚌, then we can support the liver community in every corner of Europe, come and check our new mobile office 👉can also do liver scans and liver checks #Loveyourliver and #E
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@AleksanderKrag
Aleksander Krag
9 months
@EASLnews @AASLDtweets @alehlatam @APASLnews Stand United to fight Stigma #alcoholrelatedliverdisease 👉Alcohol-related hepatitis 👉Alcohol-related cirrhosis 👉Person with Alcohol use disorder ❌ ⛔️Alcoholism and ⛔️Alcoholic ‼️ Joint statement👇
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@AleksanderKrag
Aleksander Krag
12 days
2023 journal impact factors are out- check out Liver and GI Super proud of @EASLnews journals KUDOS to the teams, AE’s, office, reviewers and authors🙏 EASL Crown Jewels in good shape❤️ @JHepatology @JHEP_Reports @ProfPaoloAngeli #JosepLlovet
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@AleksanderKrag
Aleksander Krag
29 days
I can’t wait until this door opens😎
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@AleksanderKrag
Aleksander Krag
2 months
It is with great sorrow to learn about the passing of Stephen Harrison, giant in the field, leader, inspirator, innovator and friend. Impressive legacy that can’t be overemphasised. Our thoughts goes to his family that has lost a father and husband😔
@marurinella
Maru Rinella MD
2 months
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@AleksanderKrag
Aleksander Krag
2 years
@EASLedu @AASLDtweets masterclass Liver family picture 🙏❤️ Savannah Georgia 2022
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@AleksanderKrag
Aleksander Krag
2 years
Concerned about the future of hepatology? I’m not! Heading home from a memorable EASL AASLD masterclass 🙏to our friends @AASLDtweets for organising World class faculty🤩 Privilege to hang out with the upcoming ⭐️⭐️- full of commitment, passion and visions of our joint future
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@AleksanderKrag
Aleksander Krag
3 years
#BavenoVII Acute variceal bleeding NEW guidance Prof. Thabut ➡️Less confusion✅ Hemospray ⛔️ Trombin ⛔️ FFP ⛔️ Recombinant factor VIIa ⛔️ ➡️ TIPS less contraindications ACLF✅ Hyperbilirubinemia✅ ➡️ Guidance for set-up Intubation Early endoscopy 24/7 basis
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@AleksanderKrag
Aleksander Krag
3 years
BAVENO VII premeeting is on @BavenoVII ➡️60 people with passion for portal hypertension from across the world 🌎 ➡️online to discuss and start make consensus ✅ ➡️lots of new statements to guide clinical practice 👍
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@AleksanderKrag
Aleksander Krag
1 year
#EASLCongress Day 1 is about to begin 👉 4 exciting days ahead 👉 join 7000 people from 108 countries 👉 but what’s coming today? STUDIO, opening, postgraduate course and much more!! #livertwitter @EASLnews ⁩ ⁦ @EASLedu ⁩ ⁦ @ThomasBerg24 ⁩ ⁦ @DebbieShawcros1
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@AleksanderKrag
Aleksander Krag
28 days
#EASLCongress Day minus 1 Almost ready !! A LIVER City has been built in the MiCo Center 3 places to know - where it all happens 1.Hepatology arena/ #EASLStudio 2.Goldroom and nearby 3.Exhibition/ poster space/ track hubs / skills learning 👇
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@AleksanderKrag
Aleksander Krag
27 days
Good morning Milan #EASLCongress 👉Day 1 is about to embark ✅Don’t miss: Opening ceremony Postgraduate course #EASLStudio Remember❓ The EASL congress APP Get to know the venue Arrive early to sessions it’s a big venue Wish you all a lovely day😊 Morning video 👇
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@AleksanderKrag
Aleksander Krag
8 months
So great to be in Boston again at #TLM23 with my fantastic @AASLDtweets friends. Looking forward to some great liver days. @norahterrault @WRayKimMD @EASLnews
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@AleksanderKrag
Aleksander Krag
8 months
What a wonderful #TLM23 Diwali night - festival of lights 🙏 @AASLDtweets for organising this great evening!! I enjoyed it immensely together with several liver friends.
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@AleksanderKrag
Aleksander Krag
4 months
@EASLnews Governing board meeting in Geneva #EASLCongress2024 Milan >2500 ordinary abstracts-general or parallel sessions ? Opening ceremony, awards - looks great! New CPG’s to be released! #EASLStudio live. Several innovations 😎 Also 👉 Next EIC of JHEP? 👉 New SC members?
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@AleksanderKrag
Aleksander Krag
2 years
@EASLnews @AASLDtweets Masterclass So it begins 👉Introduction and disclosure of fun facts 😳 the majority’s alternative to Hepatology is cooking 🧑‍🍳 😂- 🧐mix of knowledge, experience and passion? Otherwise full moon and roof top dinner - Nice place with great liver people 🙏
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@AleksanderKrag
Aleksander Krag
3 years
ALCOHOL, ALCOHOL #AlcoholAwarenessWeek ➡️ Alcohol related harm➡️ Check out infographics ⬇️ ❌WHO European Region 2019 180,000 cases of cancer and 92,000 cancer deaths caused by alcohol😳 🤔Any benefit from taxation on alcohol? +20% 👉 >2000 less cancers in Europe✅ why not❓
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@AleksanderKrag
Aleksander Krag
2 years
Stakeholders from across the globe 🌎 come together at @WiltonPark @EASLnews 🤜to develop a joint roadmap for fatty liver disease 👉models of care 👉research agenda 👉awareness Forming a global think tank? 🤔 - looking forward to discussions #Livertwitter
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@AleksanderKrag
Aleksander Krag
2 years
Warming up for #ILC2022 📢Media roadshow in London with @ThomasBerg24 ✅The liver is 🔥 👉Several exciting news and data to be presented at ILC in London 👉Big interest from several leading media #LiverTwitter
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@AleksanderKrag
Aleksander Krag
1 year
#EASLCongress Day 2 is about to begin 👉warm sunny lovely Vienna- 7000 liver lovers from 110 countries - What to do today? 👉very diverse program - something for all 👉RELEASE AND DISCUSSION of the new nonclosure at #EASLStudio 12.30 - come join!! @EASLnews @AASLDPresident
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@AleksanderKrag
Aleksander Krag
13 days
📣 @EASLnews Guideline APP now available on both App Store and Google play 📣Download it and get access to the best liver guidelines in the world - where you need it and when you need it.
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@EASLnews
EASLnews
13 days
📢Introducing the EASL Guidelines App – your indispensable mobile companion for accessing comprehensive and up-to-date clinical practice guidelines in hepatology💡 Now available on Google Play Store and App Store📱
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@AleksanderKrag
Aleksander Krag
1 year
How to diagnose fatty liver in children? 👉 watch out for other causes of liver disease! 👉 alternative diagnosis and dual diagnosis is more frequent in children! Check out the @ESPGHANSociety @EASLnews joint statement and guidance in @LancetGastroHep
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@AleksanderKrag
Aleksander Krag
8 months
Alcohol related liver disease now defined as part of the spectrum of steatotic liver disease! 👉good or bad? 👉how to diagnose MetALD and ALD 👉how to measure and quantify alcohol intake 👉 how to manage alcohol and metabolic risk factors Join #EASLStudio @rabataller @etrepo
@EASLnews
EASLnews
8 months
How will the new nomenclature affect healthcare pathways for those suffering with alcohol-related liver diseases?🤔 Faculty @AleksanderKrag , @juanpabloarab , Alexandre Louvet & @marurinella are looking forward to discuss this crucial topic! 📺
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@AleksanderKrag
Aleksander Krag
1 year
Liver lovers don’t miss out on this unique opportunity @EASLnews - @AASLDtweets masterclass in wonderful Madrid 2023 🙏 looking for to see and engage with the future of hepatology Great memories from last masterclass in Savannah ❤️⬇️
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@EASLnews
EASLnews
1 year
#LiverTwitter , applications for the 2023 EASL- @AASLDtweets Masterclass in Madrid Spain on 30 Nov – 2 Dec 2023 are now open! 2 days of intensive training with renowned leaders in hepatology & like-minded peers in the field 🔥 Read more & apply by 12 June:
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@AleksanderKrag
Aleksander Krag
10 months
Uniting the global community to defeat steatotic liver disease The vision: to end MASLD as a global public health threat Next step Bogotá @alehlatam ALEH congress Aug 29 and global hepatology summit editorial @JHepatology #healthylivershealthylives
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@AleksanderKrag
Aleksander Krag
28 days
We all come to #EASLCongress for the great science, excellent education, unique networking opportunities ➡️the global marketplace for liver lovers 🤓 BUT if you have time checkout 👇👇👇
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@AleksanderKrag
Aleksander Krag
2 years
@BrownHospMed @ManualOMedicine Budd- Chiari syndrome can drive massive abdominal varices and should be suspected, no cirrhosis stigma or ascites- check this case from NEJM 2014.
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@AleksanderKrag
Aleksander Krag
1 year
Wonderful! looking very much forward to welcoming you to @EASLnews Clinical School of Hepatology #EASLedu #Alcohol related Liver Disease- #SLD , #MetALD , #ALD - name it we got it ( if ALD is part😀 team @FLASH_OUH 👇 ready to host our guests ❤️
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@MohsenSubhani
Mohsen Subhani
1 year
En route to Odense Denmark 🇩🇰 to attend EASL School 🏫 of Hepatology Looking forward to meet extraordinary group of hepatologists @EASLnews @MajaThiele @rabataller @AleksanderKrag
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@AleksanderKrag
Aleksander Krag
1 year
#NordicNASHOdense2023 🙏 @marurinella stellar presentation New NAFLD nomenclature ▶️What, why now and so what? 👉difficult journey but important outcome 👉we are here to advance patient care and liver health 👉let’s stand united, speak the same ▶️reach our joint vision
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@AleksanderKrag
Aleksander Krag
3 years
Great talks at @BavenoVII by @wim_laleman @JasmohanBajaj @JonelTrebicka @AgustinAlbillos ➡️implications for clinical practice ✅ 👉Statins, Aspirin and DOAC’s of the hook as ⛔️ in cirrhosis 👉should be used when indicated ✅ 👉long term albumin stays around the corner 🛑
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@AleksanderKrag
Aleksander Krag
2 months
Happy #WorldLiverDay from Odense #OdenseLiverResearchCentre Proud of this team: Dedicated to promote liver health through science, education and awareness. @WorldLiverDay @FLASH_OUH @LiverGALAXY @OUHhospital @SyddanskUni
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@AleksanderKrag
Aleksander Krag
1 year
sTREM2 new NIT for at risk NASH @HEP_Journal 👉AUROC in validation 0.83 N=218 with TE >8 kPa 👉 ≤38 ng/ml NASH rule‐out cutoff (sens 90%; spec 52%) 👉 ≥65 ng/ml NASH rule‐in cutoff (spec 89%; sens 54%) Interested in further validation? let me know!
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@AleksanderKrag
Aleksander Krag
1 year
Ever heard about SMOC2? – me neither!   But check out what popped in our faces 👉 RNA-seq of liver biopsies, single cell integration etc     👉SMOC2 for NASH AUROC 0.88😳 – best out of 1078 differentially expressed genes   Need confirmation? YES, for sure
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@AleksanderKrag
Aleksander Krag
1 year
Looking forward to seeing you all in Vienna 👉expect innovation - next level onsite EXPERIENCE 👉wau - 2400 ordinary abstracts received 👉expect best of the best of research, education, location, interaction and communication 👉Live EASL studio 3 times daily
@EASLnews
EASLnews
1 year
#LiverTwitter : 🎯 Register for the #EASLCongress 2023 by 17 April to take advantage of the early fees and save up to 50% on the registration fee. 👉 The 🌍 world's leading hepatology faculty is looking forward to meeting you in Vienna!
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@AleksanderKrag
Aleksander Krag
5 months
Looking forward to continue the great relation and collaboration between @EASLnews and @AASLDtweets to advance knowledge, care, education and advocacy on liver diseases in Europe, US and beyond. Together we are stronger!
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@AASLDPresident
AASLD President
5 months
Grateful for the privilege to lead my esteemed colleagues this year! Excited for what lies ahead. @AASLDtweets
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@AleksanderKrag
Aleksander Krag
3 years
NAFLD - a hidden killer! 👉Society must take actions to protect its citizens better against unhealthy food 👉Medical societies must continue to work hard to increase awareness 👉GP’s must be educated to enable early detection and intervention @EASLnews
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@AleksanderKrag
Aleksander Krag
3 years
@BavenoVII Preventing first decompensation ➡️To beta-block or not to beta-block all with TE>25 that’s the question? ⚖️ evidence A1? ➡️PREDESCI NNT 9 to prevent ascites - no effect on ➕ ➡️ New IPD metaanalyse of old studies supportive but difficult to compare 👁 more data
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@AleksanderKrag
Aleksander Krag
3 years
Finally, a specific histological scoring system for ALCOHOL related liver disease @JHepatology What’s new? - Include Mallory-Denk Bodies - Include canalicular and ductular cholestasis - New grading of inflammation and fibrosis 👇
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@AleksanderKrag
Aleksander Krag
2 years
#ILC2022 Opening ceremony ➡️ 6700 delegaters EASL Secretary General @ThomasBerg24 bit welcome Honorary President Mario Rizzetto reflecting on hepatology since he discovered HDV
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@AleksanderKrag
Aleksander Krag
3 months
So it begins🫣30k +100k RCT - some way to go ☺️ @LiverAim KICKOFF - in #Barcelona
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@MajaThiele
Maja Thiele
3 months
14 months ago I drew this idea for a RCT in n=100,000 in 🇪🇸⛰️ with Pere Gines, ⁦ @miquelsb2 ⁩ ⁦ @salvatore_piano ⁩ ⁦ @schattenbergJ ⁩ ⁦ @JVLazarus ⁩ ⁦ @AleksanderKrag ⁩ & many more Today #LIVERAIM kicks-off and the dream comes true 🤩
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@AleksanderKrag
Aleksander Krag
3 months
@EASLnews at APASL in Kyoto Japan 🫶🏻 👉 Meetings with society leaders @APASLnews @AASLDtweets @alehlatam @INASL_Liver #JSN 🤝❤️ 👉 More collaboration at the global, regional and national level 👉 Joining forces👉 liver community💪 improve liver health 👍 👉 Research, education🙏
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