Which diet is superior in
#NAFLD
and
#T2D
?
Our RCT with 165 T2D pt’s in
@AnnalsofIM
High Fat Diet (50-60 E% fat) superior to Low Carb in
👉 improving glycemic control and insulin resistance
👉 inducing weight loss
👉 more improved ≥ 1 in NAS score
New insights in The Therapeutic Window of
#betablockers
and
#carvedilol
in cirrhosis
👉We ⚖️ ratios of risk/benefit, signal to noise and effect sizes
➡️ Window opens with presence of varices.
✅ Still need to scope if TE>20Kpa or platelets count <150.
LiverRisk score published
@TheLancet
@Liver_Screen
➡️ low vs high HR=471 for liver related mortality 😳
Next generation first line liver fibrosis test?🤔
👉Diagnostic AUC 0.83 vs FIB4 0.68
👉Prognostic (liver related outcomes) AUC 0.90 vs FIB4 0.84
The future of the Hepatology is here
👉EASL AASLD masterclass in Madrid ❤️
👉Talent from US meeting talent from Europe 🤓
👉Help shape the path for next generation of liver leaders in the field is the incarnation of what EASL stands for !
@EASLnews
@EASLedu
@AASLDtweets
Which is a superior referral pathway for fatty liver disease?
How to ⬇️false positives
3378 people Fib4 vs ELF vs NFS
👉FIB-4 38% eligible for referral
👉Reduced to 14% by ELF alone
👉FIB-4 + ELF reduce to 11% 👉88% correct classified
@JHepatology
Creating public awareness of fatty liver disease is not so easy.
Today I was lucky and the liver got the front page and two full pages in the National newspaper
@EkstraBladet
🙏
👉knowledge is our most powerful weapon against
#NAFLD
#Nash
👉let’s drive change together
Screening for fibrosis promote life-style changes
4,796 at risk of ALD or MASLD- 6 months and 2 years
👉ALD excessive drinking decreased from 46% to 32%
👉MASLD 35% diet ⬆️, 22% exercised⬆️, 13% weight loss ≥5%
👉impact partly lasted after 2 years
🔓
Cardiometabolic riskfactors are important in
#ALD
-and
#MetALD
👉2 minutes exercise twice a day reduces cardiovascular risk 🤔
@Camilla_Dalby
protects us with 2 minutes exercise at
@EASLedu
School of Hepatology in
#Odense
Using liver stiffness to predict and monitor the risk of decompensation and mortality in patients with alcohol-related liver disease
Check out👉- Journal of Hepatology
👉How to use and interpret repeated Fibroscan
@KHThorhauge
@GeorgSemmler
Last day of
#EASLCongress
😀😓 woke up as new EASL SG -can’t feel the difference :-)
Has been wonderful days
👉lots of learnings, interactions,
👉enjoy the last day
👉 don’t miss the symposium around the new nomenclatural 9.55
See you out there 😀
World liver day TODAY!
Fight stigma, Shame ❌
👉 barriers⬇️
👉awareness and liver health ⬆️
We need NAFLD in the WHO action plan for NCD’s
Liver diseases into policy makers agenda now❗️
Liver communities stand united💪
@EASLnews
@alehlatam
@AASLDtweets
@APASLnews
@JVLazarus
🙌 Today, April 19 is World Liver Day: a bridge between population health needs and policy makers' actions.
By raising awareness we can create a healthier world for all.
⭐ Join us in supporting
#WorldLiverDay
!
🔗
Can Rifaximin prevent progression of alcohol related fibrosis?
👉Maybe!
👉Less progression & Inflammation⬇️
➡️ 18 months RCT 136 pts
@LiverGALAXY
compliance👍
📣PoC of RCT’s in early ALD
Want to join us for more studies in early ALD/mixed NAFLD?
My first Executive meeting as EASL Vice Secretary General. We celebrate JHEP’s new IF of 25😳 Where is EASL moving?
Member benefits ⬆️, new CPG’s in pipeline, ILC 2022 London F2F- can’t wait.
Proud to join an amazing team
@ThomasBerg24
@EASLnews
@EASLedu
EASL it’s going mobile🚌, then we can support the liver community in every corner of Europe, come and check our new mobile office 👉can also do liver scans and liver checks
#Loveyourliver
and
#E
…
It is with great sorrow to learn about the passing of Stephen Harrison, giant in the field, leader, inspirator, innovator and friend. Impressive legacy that can’t be overemphasised. Our thoughts goes to his family that has lost a father and husband😔
Concerned about the future of hepatology? I’m not!
Heading home from a memorable EASL AASLD masterclass 🙏to our friends
@AASLDtweets
for organising
World class faculty🤩
Privilege to hang out with the upcoming ⭐️⭐️- full of commitment, passion and visions of our joint future
BAVENO VII premeeting is on
@BavenoVII
➡️60 people with passion for portal hypertension from across the world 🌎
➡️online to discuss and start make consensus ✅
➡️lots of new statements to guide clinical practice 👍
#EASLCongress
Day minus 1
Almost ready !!
A LIVER City has been built in the MiCo Center
3 places to know - where it all happens
1.Hepatology arena/
#EASLStudio
2.Goldroom and nearby
3.Exhibition/ poster space/ track hubs / skills learning
👇
Good morning Milan
#EASLCongress
👉Day 1 is about to embark
✅Don’t miss:
Opening ceremony
Postgraduate course
#EASLStudio
Remember❓
The EASL congress APP
Get to know the venue
Arrive early to sessions it’s a big venue
Wish you all a lovely day😊
Morning video 👇
What a wonderful
#TLM23
Diwali night - festival of lights 🙏
@AASLDtweets
for organising this great evening!!
I enjoyed it immensely together with several liver friends.
@EASLnews
Governing board meeting in Geneva
#EASLCongress2024
Milan >2500 ordinary abstracts-general or parallel sessions ?
Opening ceremony, awards - looks great! New CPG’s to be released!
#EASLStudio
live.
Several innovations 😎
Also
👉 Next EIC of JHEP?
👉 New SC members?
@EASLnews
@AASLDtweets
Masterclass
So it begins
👉Introduction and disclosure of fun facts 😳 the majority’s alternative to Hepatology is cooking 🧑🍳 😂- 🧐mix of knowledge, experience and passion?
Otherwise full moon and roof top dinner - Nice place with great liver people 🙏
ALCOHOL, ALCOHOL
#AlcoholAwarenessWeek
➡️ Alcohol related harm➡️ Check out infographics ⬇️
❌WHO European Region 2019 180,000 cases of cancer and
92,000 cancer deaths caused by alcohol😳
🤔Any benefit from taxation on alcohol? +20% 👉 >2000 less cancers in Europe✅ why not❓
Stakeholders from across the globe 🌎 come together at
@WiltonPark
@EASLnews
🤜to develop a joint roadmap for fatty liver disease
👉models of care
👉research agenda
👉awareness
Forming a global think tank? 🤔 - looking forward to discussions
#Livertwitter
Warming up for
#ILC2022
📢Media roadshow in London with
@ThomasBerg24
✅The liver is 🔥
👉Several exciting news and data to be presented at ILC in London
👉Big interest from several leading media
#LiverTwitter
#EASLCongress
Day 2 is about to begin
👉warm sunny lovely Vienna- 7000 liver lovers from 110 countries - What to do today?
👉very diverse program - something for all
👉RELEASE AND DISCUSSION of the new nonclosure at
#EASLStudio
12.30 - come join!!
@EASLnews
@AASLDPresident
📣
@EASLnews
Guideline APP now available on both App Store and Google play
📣Download it and get access to the best liver guidelines in the world - where you need it and when you need it.
📢Introducing the EASL Guidelines App – your indispensable mobile companion for accessing comprehensive and up-to-date clinical practice guidelines in hepatology💡
Now available on Google Play Store and App Store📱
How to diagnose fatty liver in children?
👉 watch out for other causes of liver disease!
👉 alternative diagnosis and dual diagnosis is more frequent in children!
Check out the
@ESPGHANSociety
@EASLnews
joint statement and guidance in
@LancetGastroHep
Alcohol related liver disease now defined as part of the spectrum of steatotic liver disease!
👉good or bad?
👉how to diagnose MetALD and ALD
👉how to measure and quantify alcohol intake
👉 how to manage alcohol and metabolic risk factors
Join
#EASLStudio
@rabataller
@etrepo
How will the new nomenclature affect healthcare pathways for those suffering with alcohol-related liver diseases?🤔
Faculty
@AleksanderKrag
,
@juanpabloarab
, Alexandre Louvet &
@marurinella
are looking forward to discuss this crucial topic!
📺
Liver lovers don’t miss out on this unique opportunity
@EASLnews
-
@AASLDtweets
masterclass in wonderful Madrid 2023
🙏 looking for to see and engage with the future of hepatology
Great memories from last masterclass in Savannah ❤️⬇️
#LiverTwitter
, applications for the 2023 EASL-
@AASLDtweets
Masterclass in Madrid Spain on 30 Nov – 2 Dec 2023 are now open!
2 days of intensive training with renowned leaders in hepatology & like-minded peers in the field 🔥
Read more & apply by 12 June:
Uniting the global community to defeat steatotic liver disease
The vision: to end MASLD as a global public health threat
Next step Bogotá
@alehlatam
ALEH congress Aug 29 and global hepatology summit
editorial
@JHepatology
#healthylivershealthylives
We all come to
#EASLCongress
for the great science, excellent education, unique networking opportunities ➡️the global marketplace for liver lovers 🤓
BUT if you have time checkout
👇👇👇
@BrownHospMed
@ManualOMedicine
Budd- Chiari syndrome can drive massive abdominal varices and should be suspected, no cirrhosis stigma or ascites- check this case from NEJM 2014.
#NordicNASHOdense2023
🙏
@marurinella
stellar presentation New NAFLD nomenclature ▶️What, why now and so what?
👉difficult journey but important outcome
👉we are here to advance patient care and liver health
👉let’s stand united, speak the same ▶️reach our joint vision
sTREM2 new NIT for at risk NASH
@HEP_Journal
👉AUROC in validation 0.83
N=218 with TE >8 kPa
👉 ≤38 ng/ml NASH rule‐out cutoff (sens 90%; spec 52%)
👉 ≥65 ng/ml NASH rule‐in cutoff (spec 89%; sens 54%)
Interested in further validation? let me know!
Ever heard about SMOC2? – me neither!
But check out what popped in our faces
👉 RNA-seq of liver biopsies, single cell integration etc
👉SMOC2 for NASH AUROC 0.88😳 – best out of 1078 differentially expressed genes
Need confirmation? YES, for sure
Looking forward to seeing you all in Vienna
👉expect innovation - next level onsite EXPERIENCE
👉wau - 2400 ordinary abstracts received
👉expect best of the best of research, education, location, interaction and communication
👉Live EASL studio 3 times daily
#LiverTwitter
: 🎯 Register for the
#EASLCongress
2023 by 17 April to take advantage of the early fees and save up to 50% on the registration fee. 👉
The 🌍 world's leading hepatology faculty is looking forward to meeting you in Vienna!
Looking forward to continue the great relation and collaboration between
@EASLnews
and
@AASLDtweets
to advance knowledge, care, education and advocacy on liver diseases in Europe, US and beyond. Together we are stronger!
NAFLD - a hidden killer!
👉Society must take actions to protect its citizens better against unhealthy food
👉Medical societies must continue to work hard to increase awareness
👉GP’s must be educated to enable early detection and intervention
@EASLnews
@BavenoVII
Preventing first decompensation
➡️To beta-block or not to beta-block all with TE>25 that’s the question?
⚖️ evidence A1?
➡️PREDESCI NNT 9 to prevent ascites - no effect on ➕
➡️ New IPD metaanalyse of old studies supportive but difficult to compare
👁 more data
Finally, a specific histological scoring system for ALCOHOL related liver disease
@JHepatology
What’s new?
- Include Mallory-Denk Bodies
- Include canalicular and ductular cholestasis
- New grading of inflammation and fibrosis
👇
#ILC2022
Opening ceremony
➡️ 6700 delegaters
EASL Secretary General
@ThomasBerg24
bit welcome
Honorary President Mario Rizzetto reflecting on hepatology since he discovered HDV