Our new paper is out! We report the human Bre1 complex (aka RNF20-RNF40) structure bound to the nucleosome, providing insights into its H2BK120-specific monoubiquitination, regulation, and possible paralog-specific function. Congrats
@thiamine_0024
!
こわい
"They do not provide any probability estimates, so significance, in a statistical sense, of the result is zero."
"A prime example of how not to do statistical analysis with model comparison."
"I think it is unfair to your colleagues to send such a paper for review."
Excited to share major progress on next generation of AlphaFold! Together with
@IsomorphicLabs
, we’ve significantly advanced accuracy & expanded coverage beyond proteins to other key biomolecular classes. Continuing to accelerate science at digital speed
Our paper is out in Nature Catalysis
@NatureCatalysis
(3rd paper by collaboration with Suga Lab at Univ. Tokyo ). Congrats to Yuchen (UT
@UTokyo_News_en
) and Hamada-san (YCU
@YCU_koho
)!