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James Wise Profile
James Wise

@jamespaulwise

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Partner @Balderton . Investing in AI, health and energy. UK Industrial Development Board. Author of Start-Up Century. Mostly Generative.

United Kingdom
Joined March 2010
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@jamespaulwise
James Wise
1 year
The worrying mistake made by this programme, groups like Just Stop Oil, & Chris below, is to approach climate change as a civil rights challenge rather than a technology challenge. We cannot just legislate for lower carbon emissions globally, we have to innovate. This challenge
@ChrisGPackham
Chris Packham
1 year
Personally , I've now reached a point where I believe breaking the law for the climate is the ethically responsible thing to do . #ChrisPackhamC4 | @Channel4
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@jamespaulwise
James Wise
11 months
Today my book, Start-Up Century, is released in the UK. The book includes research, interviews and insights from 100s of entrepreneurs and policy makers. But it's based on two simple observations: that more people than ever are becoming entrepreneurs, while the path to scaling
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@jamespaulwise
James Wise
2 months
@paulg The American legal system imprisoned the founder of Silkroad to life, chased Mike Lynch around the world through extradition ( only to be found innocent ) and hounded Aaron Swartz to his death, amongst other things. I don’t no the details for Pavel, but the US is no haven.
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@jamespaulwise
James Wise
11 months
The board fired the CEO and 1 hour later, 1000s of customers ( including us ) received an email saying you now have to pre-pay for OpenAI because they can’t wait until the end of the month for the money. It doesn’t take a super sleuth to work out what’s happened.
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@jamespaulwise
James Wise
1 year
Ever wanted to talk to a book? Now you can! In what I think is a first, you can now chat with Start-Up Century using the latest AI model. You can ask it questions like whose the author? Or how will AI affect employment? Check it out at .
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@jamespaulwise
James Wise
6 months
Given the incredible advances in technology, there's surprisingly little discussion of the positive impact it can have on our health, wealth and planet. Introducing What's Next, an interview series with some of the leading founders and investors behind the technological
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@jamespaulwise
James Wise
2 months
We @balderton have raised $1.3B in new venture & growth funds to continue investing in the UK & Europe’s leading technology companies. It’s obviously important if you’re building a company, so if you’re raising from seed -> IPO get in touch! But it’s also important for much
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@jamespaulwise
James Wise
4 months
Celebrating Father’s Day by becoming a new one! Cara Evelyn Kay Wise was born on 13th June to two overjoyed parents in @LizziePaton & I. Thrilled & exhausted.
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@jamespaulwise
James Wise
4 months
Amazing to think Revolut didn’t exist a decade ago. This year alone it will save its users £1Bs, create 1000s of jobs & generate £100Ms in corporate & income taxes for HMRC. Now we just need to create dozens of Revoluts. It’s the only way Britain grows.
@CityAM
City A.M.
4 months
Revolut has swung to an annual profit and nearly doubled its revenue for 2023 as the fintech filed its first timely set of results in years.
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@jamespaulwise
James Wise
8 months
My book, Start-Up Century, comes out in the USA today! If you're interested in why record numbers of people are starting businesses, why the traditional firm is shrinking and why entrepreneurship is becoming one of the most popular ways of working - check it out. With record
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@jamespaulwise
James Wise
4 months
If we want to improve our health, we first need to know what's going on in our bodies. For this week's episode of 'What's Next' I sat down with @RENCIRCI of @Savahealth to discuss their breakthrough sensor which provides realtime data on our many different molecules & hormones,
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@jamespaulwise
James Wise
1 year
Excited to announce that my book, Start-Up Century is now available to order ahead of it's release on November 23rd with @BloomsburyBiz . It covers why more of us than ever are going to become entrepreneurs. It explores, through interviews & research, what makes people start-up,
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@jamespaulwise
James Wise
5 months
Astonishing that UK based Arm is now worth more ($145B) than Intel ($130B).
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@jamespaulwise
James Wise
5 months
Following the news of their £35M funding round, I sat down with James Field, CEO and founder of @labgeni_us for the latest episode of What's Next. LabGenius is on a mission to not only find novel therapeutics, but to use AI to augment the scientific method itself. In this
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@jamespaulwise
James Wise
9 months
My book, Start-Up Century, comes out in the USA and Canada on February 14th. If you're interested in why record numbers of people are starting businesses, why the traditional firm is shrinking and why entrepreneurship is becoming one of the most popular ways of working - check
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@jamespaulwise
James Wise
6 months
An exceptional write up in the @thetimes on @wayve_ai ’s technology and the experience of riding in an autonomous vehicle through Kings Cross. Huge congratulations to @alexgkendall and the team on their $1B funding round - the largest ever for an AI company in Europe. Balderton
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@jamespaulwise
James Wise
1 year
If you want to help tackle climate change, and we must then you can: - work for a climate tech company - put your pension or savings into carbon reduction funds or companies - buy carbon neutral products and services - vote for parties that will invest capital into carbon
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@jamespaulwise
James Wise
7 months
I know it’s a few weeks ago now but the @justpark story deserved a lot more coverage. - An incredible entrepreneurial journey of effort over a decade - More international investment into UK tech companies - A great outcome for both the taxpayer ( through the Future Fund ) and
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@jamespaulwise
James Wise
4 months
‘Wise is single minded in what he wants: policies that will turn the UK into a country that nurtures & promotes entrepreneurship’ My interview in @CityAM on how the UK can utilise one of our least appreciated national assets - ambition.
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@jamespaulwise
James Wise
11 months
I’ve sat on dozens of start-up boards and having professional board members matters. OpenAIs board was woefully under experienced and didn’t have skin in the game. It’s not unusual for a start-up, they just happen to be the one that cracked the most important technology of the
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@jamespaulwise
James Wise
1 year
This chart never ceases to blow my mind. Fewer & fewer people are needed by firms for them to be successful. We're already seeing companies with just a few dozen people generate billions in revenues & create world changing products. In the next few years I'm certain there will
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@jamespaulwise
James Wise
4 months
. @soundboy I’m waiting for you to say it!
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@jamespaulwise
James Wise
4 months
The American mind can’t comprehend this.
@amyrlewin
Amy Lewin
4 months
NEW: European VC returns are better than North American VC returns over 10 and 15 year horizons, finds a new report from @InvestEuropeEU & Cambridge Associates.
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@jamespaulwise
James Wise
11 months
Hugely grateful to everyone who came to the UK book launch for Start-Up Century yesterday, we were completely sold out by the end. Let’s hope the Chancellor has more good news for people starting and running their own businesses later today!
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@jamespaulwise
James Wise
2 months
Incredibly niche content: If you’re an alumni of Oxford you have until midnight to register to vote for the new Chancellor. The first time you can vote online & not in person! And it’s probably the only time you’ll get a say in the University’s direction for a decade or more.
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@jamespaulwise
James Wise
5 months
Want to know what we might be eating in the future? Our latest episode of What’s Next is out with Benjamina Bollag of @uncommonbio . We discuss: - why lab-grown meat can be better for our health, pockets & the planet 🥓 - how breakthroughs in cell research are changing the way
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@jamespaulwise
James Wise
2 months
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Matt Rouif
2 months
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@jamespaulwise
James Wise
7 months
Following the ‘AI safety summit’ last year, we should be hosting an even bigger ‘AI success summit’ this year: - showcase recent breakthroughs across the NHS, schools & gov where advances in AI are making a real difference - demonstrate the capabilities of the latest tools and
@BBCNews
BBC News (UK)
7 months
NHS AI test spots tiny cancers missed by doctors
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@jamespaulwise
James Wise
1 year
The barbarism and cowardice shown by Hamas in its attack this weekend is sickening. Those celebrating or defending it under the Palestinian flag are at best wilfully ignorant of the horror of Hamas in Palestine & Israel, or do so because of a much darker sickness. In either
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@jamespaulwise
James Wise
1 year
I never said these words, this is an entirely generated video of me, and sadly I’m not fluent in German. But virtual avatars are getting really good. If you’re working on the tools we’ll need to prevent this new tech being used for fraud, get in touch with @_lauramcginnis or
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@jamespaulwise
James Wise
6 months
Bored of the negative narrative around new technologies? So am I. Introducing "What's Next?" - a new video series aimed at improving the conversation around emerging tech. We've interviewed the founders of companies behind breakthroughs in fields as diverse as self-driving
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@jamespaulwise
James Wise
4 months
Just like with nuclear power - some countries have rushed to regulate a new technology based on imagined risks, costing them very real & immediate benefits. Can only hope UK avoids the same fate.
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@jamespaulwise
James Wise
2 months
I'm very time-poor right now (new father, work, Oasis ticket queue) and I haven't used HTML/CSS since Dreamweaver 3. But I managed to spin-up a new and interactive version of the website for my book (Start-Up Century) in 15 minutes with . I can't
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@jamespaulwise
James Wise
29 days
We’re backing @convergence_ai_ . The team have built the most incredible product I’ve seen in years. A web agent that you can teach to do tasks exactly as you would. The ability to learn is the missing link between dumb software & generalised, productive agents. And while they
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@jamespaulwise
James Wise
3 months
The UK & EU should follow the US lead here. Non-competes stifle innovation, and make hiring harder for employer and employees.
@unusual_whales
unusual_whales
3 months
BREAKING: The Biden administration's ban on noncompete clauses has been upheld in court, per MorePerfectUnion. As of now, virtually all noncompete agreements with bosses will be banned and voided beginning September 4.
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@jamespaulwise
James Wise
4 months
The important point here is that venture as a whole has come back incredibly strong in 2024 - and in the UK in particular. It’s a great time to start a business.
@CityAM
City A.M.
4 months
British firms have received nearly a third of European venture capital tech funding so far this year, new data shows, as investors flock back to London and Cambridge bolsters its credentials as an international hub. VC investment in the UK tech sector came in at £7.4bn for the
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@jamespaulwise
James Wise
1 year
On a day that’s packed with AI, thanks to @business for having me on to speak about - AI! Regulation is vital, but let’s regulate the uses of AI, not the tools that entrepreneurs need to innovate. Keep the models open! #Freetheweights
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@jamespaulwise
James Wise
3 months
Impressive that less than 24 hours since @jonno_evans and I released a podcast calling for a department for AI success, @matthewclifford and DSIT have launched it! Congrats!
@SciTechgovuk
Department for Science, Innovation and Technology
3 months
A new plan led by @matthewclifford will use AI to boost growth and improve our public services. The AI Opportunities Action Plan will identify how to boost uptake of AI across the public and private sectors to increase productivity. (1/2)
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@jamespaulwise
James Wise
4 months
I have incredible friends running in this election for all the main parties. The sacrifices they are making to their personal & professional lives are immense. This is a great article capturing why we should recognise the demands we place on our politicians more if we want good
@j_amesmarriott
James Marriott
4 months
I wrote this about why we should be nicer to politicians
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@jamespaulwise
James Wise
7 months
Nowhere in the world does meeting rooms like Paris. Discussing how AI breakthroughs can help build a new gilded age this morning. Thanks to @jpmorgan for hosting our breakfast. @MistralAI @OwkinScience @finsterai @deepset_ai @giskard_ai , AdaptiveML, Holistic.
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@jamespaulwise
James Wise
1 year
Venture capital is coming out of the 2020-2022 bubble focussed on the things that matter:
@yoramdw
Yoram Wijngaarde
1 year
The top 30 Emerging Technologies in venture capital. Via @dealroomco
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@jamespaulwise
James Wise
1 year
My piece in @guardian today: while academics debate the rise of the Terminator, the real and present challenge is how new AI tools are being used to defraud people. We made imitating humans through the Turing test the gold-standard for AI, now it’s being used against us.
@guardianopinion
Guardian Opinion
1 year
Imagine your child calling for money. Except it’s not them – it’s an AI scam | James Wise
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@jamespaulwise
James Wise
2 years
An astounding graph. The most productive companies are getting smaller, but there’s two big follow-on effects from this: Employees in larger firms are getting paid less, a phenomenon @JamesPlunkett wrote about recently, creating firm ‘unequality’…
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@jamespaulwise
James Wise
9 months
British dynamism.
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@jamespaulwise
James Wise
4 months
Kicking off London Tech Week with @peterkyle and @Dom_Hallas of Start Up Coalition. We hope all manifestos will focus on how the UK can become an even better place to start and scale technology companies.
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@jamespaulwise
James Wise
1 year
One of the consistent trends I’m seeing in our portfolio is the use of generative AI to make complex products more accessible for non-experts. In short, AI is massively expanding the best products’ TAMs. This is true for incumbents, as well as start-ups. I wrote about what
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@jamespaulwise
James Wise
5 months
When the Times’s Rich List came out in 1989, they said ‘the surest way to a fortune was to be a landowner, preferably with a title’ Today they lead with ‘the list is a celebration of aspiration….(with) stories of extraordinary entrepreneurship’ Britains transformation into a
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@jamespaulwise
James Wise
7 months
Have been asked for a reference on a fund whose single GP is pitching themselves as an AI & deep tech expert. Two years ago they had a kitty NFT as their profile pic & their largest cheque was into a now defunct snack delivery company. I guess you have to admire the hustle?
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@jamespaulwise
James Wise
8 months
The @photoroom_app team have built one of the world's most popular AI products. Over 150 million people have used it to improve images - whether it's for their small business, online shop, event promotion, social media or just for fun. It's a beautiful experience, and we're
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@jamespaulwise
James Wise
2 months
Following the announcement of our new funds, I've pulled together some thoughts on: - why venture capital matters - how fundraising in Europe has changed - our commitment to both our LPs and founders Too long for an X thread, but worth a read I promise:
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@jamespaulwise
James Wise
1 year
I’ve always thought success at work is a marathon not a sprint and now we have the data to prove it! All jobs, but especially entrepreneurial roles need you to take time to reflect and recoup. It’s a key challenge addressed in #StartUpCentury and in our Balderton well founded
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@jamespaulwise
James Wise
11 months
The good people @Dauntbooks are offering customers two very differing visions of our technology determined future between @yanisvaroufakis and myself.
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@jamespaulwise
James Wise
1 year
Our hackathon with @AnthropicAI , @deepset_ai , @cerebral_valley & others in London this weekend has had over 1,000 applicants. There’s a truly astonishing number of talented and ambitious people. Invites are being sent out to the c.300 people we can accept - but we will look to
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@jamespaulwise
James Wise
9 months
While we are overwhelmed with the stories of sportspeople and celebrities, there's nowhere near enough content for people on the motivation, challenges and learnings from entrepreneurship. Especially British ones. This is great to see from Tom and well worth the watch. With over
@t_blom
Tom Blomfield
9 months
Before I was 30 years old, I’d started 2 companies that are each now worth over a billion dollars. And it almost broke me. Here’s my story.
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@jamespaulwise
James Wise
1 year
We want to see more people benefit from AI. Following the AI Safety Summit - we are hosting the UK's biggest AI hackathon next weekend, with unique support from @AnthropicAI , @cerebral_valley , @Haystack_AI & others. Come & build with us here:
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@jamespaulwise
James Wise
8 months
The new gold standard for building a $100M revenue software business is 100 FTE, and shrinking.
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@jamespaulwise
James Wise
4 months
The latest episode of What's Next was an incredible deep dive into drone delivery with @realBobbyHealy , founder of @MannaAero . We discuss: - why he sees drone delivery as 'the biggest opportunity imaginable' - how Manna does drone deliveries today everywhere from Ireland to
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@jamespaulwise
James Wise
6 months
Great to have the Economic Sec to the Treasury @BimAfolami address fintech founders @balderton last night. The UK really is a global leader when it comes to fintech, but there’s a lot of work to be done if we want to stay there.
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@jamespaulwise
James Wise
9 months
I'll be speaking at the House of Lords today alongside @kevinhollinrake & @jogideon about my book, Start-Up Century as part of @TenThinkTank 's work to make Britain one of the best places in the world to start and grow a business. If you're starting a company, a freelancer or
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@jamespaulwise
James Wise
4 months
We won’t, because we’re British. But the regeneration of Manchester from the 1980s - 2010s should celebrated & shared as a blueprint to other post-industrial cities. Much of that success was down to Sir Howard Bernstein. May his memory be a blessing.
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@jamespaulwise
James Wise
2 months
Let’s go 🚀
@Jefferson_MFG
Jefferson
2 months
🇬🇧FASTER THAN CONCORDE! British aerospace manufacturer Reaction Engines is celebrating a major hypersonic propulsion system milestone. The Abingdon-based firm has successfully demonstrated the integration of its innovative precooler technology with existing jet-engine
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@jamespaulwise
James Wise
1 year
One of the biggest shifts in the way we work in coming years will be the need for life-long and regular learning. Excited to share our investment in Grasp, and support its mission to use the latest in AI to provide personalised and adaptive learning throughout your career.
@EU_Startups
EU-Startups
1 year
Online learning platform Grasp announces it has raised €3.6 million seed funding led by @balderton Capital 🇬🇧 💡
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@jamespaulwise
James Wise
1 year
Looks especially good on an orange background (not included)....
@daniellenewnham
Danielle Newnham
1 year
Can’t wait to read! Start-Up Century: Why we're all becoming entrepreneurs - and how to make it work for everyone #startups #founders #Entrepreneur
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@jamespaulwise
James Wise
7 months
In Start-Up Century I wrote about how automating code with AI was going to result in millions more people starting businesses. @Replit are making that happen today:
@amasad
Amjad Masad
7 months
developers should now assume their "not a coder" managers can code
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@jamespaulwise
James Wise
8 months
This is my first year of having a child old enough for World Book Day and can I just say are you all completely mad? You do this every year? Do we parents not have enough on than competing over who can hand weave the most authentic Gruffalo costume?
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@jamespaulwise
James Wise
6 months
Adding @danielsusskind ’s new book to the Balderton library. I’m only a few chapters in - but it’s a powerful read on the most important economic and political question of our time: growth.
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@jamespaulwise
James Wise
2 years
In an attempt to save people’s time when raising, here are the three areas I’m trying to focus on this year, condensed into 400 words: ‘A.I’ for All The Great Energy Transition Scalable Healthcare If you’re working on these challenges, get in touch.
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@jamespaulwise
James Wise
1 month
Welsh is so difficult Google AI has decided to skip it and talk to actual whales instead.
@GoogleAI
Google AI
1 month
Introducing our new whale bioacoustics model, which can identify eight distinct species, including multiple calls for two of those species. The model even includes the “Biotwang” sounds recently attributed to the Bryde’s whale. Learn more at:
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@jamespaulwise
James Wise
1 year
@jburnmurdoch @xianghui90 @oren_reshef @Zhou_Yu_AI It's a good piece. But there are already >10k freelancers on Upwork who list ChatGPT as a skill, presumably to respond to work that wasn't there a year ago. Treating skills as static will always lead you to conclude jobs are in decline.
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@jamespaulwise
James Wise
9 months
Hundreds of people turning up ( and tuning in ) to our Gen AI builder events here @balderton . Some great demos from @deepset_ai , @JinaAI_ & TitanML. If you’re interested in joining in future sign up to our newsletter!
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@jamespaulwise
James Wise
4 months
What gets measured gets managed. Great to announce our investment in Sava Health - a breakthrough British biosensor company which can track dozens of molecules from glucose to cortisol through a micropatch on your skin. Read more about it and their clinical trials below:
@Siftedeu
Sifted
4 months
Balderton backed the startup as it looks to take its device through clinical trials and scale manufacturing capabilities.
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@jamespaulwise
James Wise
5 months
We are so back 🇬🇧
@HBrubanter
Herb Brubanter
5 months
BBC News - Mechanic builds record-breaking 50mph wheelbarrow
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@jamespaulwise
James Wise
11 months
Delighted that @TechCrunch has picked Start-Up Century as one of their Christmas reads this year. A great gift for the budding entrepreneur in your life!
@TechCrunch
TechCrunch
11 months
8 authors and their 8 gift book picks for this holiday season by @abracarioca
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@jamespaulwise
James Wise
10 months
This was certainly true over the last decade. However the data suggests there’s been a significant shift. Interest in starting a business, especially from people under the age of 25, is at record highs in the UK. As is the number of people who have already sold something online.
@paulg
Paul Graham
10 months
Met a British startup founder today who'd studied engineering at Oxford. He said the majority of his fellow students had since gone into finance or consulting. In effect there is a brain drain *within* the UK, as engineers emigrate to fields where they don't build anything.
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@jamespaulwise
James Wise
1 year
My digital avatar & I presenting on the @BAFTA stage last night. Unlike me, it stuck to it’s lines….
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@jamespaulwise
James Wise
9 months
I'm delighted to be giving a keynote address at this year's Start-Up Show, the biggest event of it's kind, at King’s College London on 27 Jan. I'll be talking about my book, Start-Up Century, with The Times' @jameshurley and discussing why and how more of us than ever are
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@jamespaulwise
James Wise
3 months
Small modular nuclear reactors (SMRs) are considered by some to be the most important clean energy breakthrough of this decade. Loved speaking to Jake, the co-founder of BlueEnergy about: - why SMRs can be a cheaper, more elegant & safer solution to many of our energy needs -
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@jamespaulwise
James Wise
1 year
I feel like this should be required viewing for everyone attending the AI safety summit in a few weeks. Bill Gurley’s incredible talk on regulatory capture - ‘regulation is the friend of the incumbent’
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@jamespaulwise
James Wise
4 months
Fortunately the good people @StartupCltn have put together a manifesto with some good ideas of how we do that!
@StartupCltn
Startup Coalition
4 months
Britain’s startup and scaleup ecosystem is at a crossroads. And whoever forms the next Government has some serious decisions to make. That's why today we are launching our Startup Manifesto. Read it here: Or find out more below 👇
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@jamespaulwise
James Wise
4 months
Huge congratulations to @peterkyle , given the pace of change in frontier technology at the moment this is one of the most critical jobs in the country - but it’ll be fun too!
@10DowningStreet
UK Prime Minister
4 months
Peter Kyle MP @peterkyle has been appointed Secretary of State for Science, Innovation and Technology @SciTechgovuk .
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