D. Allan Drummond Profile Banner
D. Allan Drummond Profile
D. Allan Drummond

@dallandrummond

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Associate professor of biochemistry & molecular biology and genetic medicine @UChicago . Art @dadrummondart “Not an artist per se” — Seattle Magazine

Chicago, IL
Joined November 2010
Don't wanna be here? Send us removal request.
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@dallandrummond
D. Allan Drummond
4 months
How do cells efficiently respond to stress? Transcriptional stress responses are well-known—and in our latest study, we discover that cells use biomolecular condensation to redirect translation from old to new mRNAs 1/n
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@dallandrummond
D. Allan Drummond
3 years
A first in 15 years: every member of the lab is currently funded by a fellowship or prize they've competed for and won. On top of doing great science, they've rallied to critique each others' proposals, practice talks, share lessons learned. Super-proud.
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@dallandrummond
D. Allan Drummond
6 years
Associate professor as of today. Such a strange naming scheme. Who are we associated with? Who do assistant professors assist? And what, exactly, are full professors full of?
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@dallandrummond
D. Allan Drummond
4 years
Unsolicited advice: the idea that you are *almost done* with this experiment/paper/project will cause you huge amounts of misery that is almost unparalleled in its senselessness. You can let go of this belief, and little will change except your day-to-day happiness.
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@dallandrummond
D. Allan Drummond
6 years
“Mother/Daughter,” 2018. Bronze, silver, 3D printed steel, apatite. The jewels get their color from phosphorus, which links each base of DNA. Depicting late anaphase in budding yeast, where — unlike in our cells — the nuclear membrane remains intact. A piece from my debut show.
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@dallandrummond
D. Allan Drummond
5 years
This bizarre belief that establishing causality requires uncovering the mechanism is one of the most progress-inhibiting misconceptions in science. Establishing causality requires only controlled perturbations — you need not know anything about mechanism. +1 @kph3k
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@dallandrummond
D. Allan Drummond
4 years
mRNA levels tell you almost nothing about protein levels.
@Ti_Enjoli
👑👩🏽‍🔬Dr. Mother of Astrocytes, PhD🧠🧬
4 years
Name a popular scam that most Scientists believe. I'll go: the pippette cook book
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@dallandrummond
D. Allan Drummond
3 years
Subcellular Imaging Reveals that Things Happen at Different Places
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@dallandrummond
D. Allan Drummond
6 years
The Sparrow. In which a scientist slowly descends into madness.
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@dallandrummond
D. Allan Drummond
3 years
A massive and fun biological puzzle, still unsolved: Why are there so few marine insects 🪰, and so few terrestrial crustaceans 🦀? Insects likely evolved from crustaceans; they're all arthropods. Both have coexisted for hundreds of millions of years. 1/4
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D. Allan Drummond
4 years
A drift of population geneticists A digest of molecular biologists A loop of crystallographers A convergence of evolutionary biologists An assumption of biophysicists (To all my colleagues: I love you)
@BeccaBrass
Rebecca Brassington, MD
4 years
A murder of crows. A pod of whales. A leap of leopards. What would describe a group in your specialty? #MedTwitter
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@dallandrummond
D. Allan Drummond
3 years
A few “do not disturb, I am writing a grant” signs from my door over the years
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@dallandrummond
D. Allan Drummond
2 years
Our review of stress granules and related phenomena is out @MolecularCell ! An unusually pointed piece, aimed at stimulating progress in a mature field where many of the most basic questions remain unanswered. Like: what do stress granules do? 1/5
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@dallandrummond
D. Allan Drummond
3 years
As application season approaches, so do the emails: "Dear Dr. Ummond, ..."
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@dallandrummond
D. Allan Drummond
7 years
Got *two* tenure letters in the mail today. Yes, @SouthwestAir , it sure does.
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@dallandrummond
D. Allan Drummond
7 years
Draw me like one of your model organisms.
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@dallandrummond
D. Allan Drummond
1 year
Hot off the presses...our coolest study ever...seriously! By comparing a thermophile, mesophile, and cryophile, we show conservation and ecological tuning of heat-triggered biomolecular condensation from the ecological to submolecular scales 🔥🔬❄️ (🧵)
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D. Allan Drummond
3 years
Thrilled to share our latest on @biorxivpreprint : major work by grad student @whoisyoo about what molecular chaperones are really good at. It turns out they *love* to disperse stress-induced biomolecular condensates. Often speculated; now demonstrated. 🧵
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@dallandrummond
D. Allan Drummond
9 years
Cell division, in solid bronze. Late-anaphase budding yeast, mother & daughter. #3dprinting @shapeways @yeastgenome
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D. Allan Drummond
2 years
Bit late now mate
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@dallandrummond
D. Allan Drummond
6 years
Proud and terrified to announce: My debut solo sculpture show, “Curiosity,” opens at Roq La Rue Gallery in Seattle on Friday, December 7th. I’ll be there opening night. @roqlarue 1/3
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D. Allan Drummond
3 years
Happy to say it was easier this time! MIRA for next five years starts 1/1, awarded on the first try. Keep at it, folks. (Oh...and we're hiring!)
@dallandrummond
D. Allan Drummond
7 years
ND, ND, ND, ND, ND, ND, 44, ND, ND, 10.
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D. Allan Drummond
4 years
Gave a talk today and was reminded: after all these years, I still have profound stage fright. Can't catch my breath, heart racing, for the whole talk. It's physical. Has nothing to do with mechanics, or command, or comfort. Hopefully few noticed...but I did. Just like always.
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D. Allan Drummond
4 years
Art by scientists by request: Hand-finished bronze white-lined sphinx moth (Hyles lineata) pendant, nestled in its microecology for safe traveling. Plus a silver version. Everything designed and finished by me, mix of old-school and new-school methods. 🦋
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@LiamHoltLab
Liam Holt
4 years
1/2 Art by scientists! So much great work out there. Let’s see what you’ve all been working on. RT with your work so we can organize a gallery poster session...
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D. Allan Drummond
3 years
We Didn't Learn Anything New, But Hey, Single Cells
@xkcd
Randall Munroe
3 years
Types of Scientific Paper
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D. Allan Drummond
3 years
Out today in @MolecularCell ! "Chaperones directly and efficiently disperse stress-triggered biomolecular condensates." Simple message resulting from the herculean effort of @whoisyoo with assists from @JAM_Bard and Evgeny Pilipenko. Enjoy!
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D. Allan Drummond
7 years
ND, ND, ND, ND, ND, ND, 44, ND, ND, 10.
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@dallandrummond
D. Allan Drummond
2 years
Started my PhD at 29.
@panickedpostdoc
Panicking Professor
2 years
How old were you when you finished your PhD? I was 29. @AcademicChatter #postdoclife #phdchat @PostdocVoice
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D. Allan Drummond
5 years
AUG 1: the day we Met. #RNADay
@lianafaye
Dr. Liana Lareau
5 years
Happy #RNAday (AUG 1)! The original and best macromolecule. It splices! It DICERs! It catalyzes protein synthesis!
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D. Allan Drummond
5 years
Take a moment to read Harmit Malik's story. He's one of the truly good ones, and the way he talks about the origins and development of ideas, professional development and mentorship, the future of basic science, and fridge magnets deserves your attention.
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D. Allan Drummond
3 years
Yesterday marked 15 years of the Drummond Lab and a decade @uchicago . The group went all-out and threw an amazing party. Plenty of sweetness, teasing, blasts from the past, and general nerd joy. It's the people, people. ❤️🔬❤️
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D. Allan Drummond
2 years
@TrumanLab We make our figures and posters in @inkscape . Free, powerful.
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@dallandrummond
D. Allan Drummond
7 years
15 years ago: decided to become a scientist, quit my HR job, started grad school. Yesterday: submitted my promotion package.
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D. Allan Drummond
9 years
3D-printed dividing cell is now available on @shapeways . Budding yeast, late anaphase.
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D. Allan Drummond
3 years
I (middle-aged scientist) just realized that “oval” literally means egg-like. 🤦🏻‍♂️
@WryCritic
Natalia Jagielska
3 years
science
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D. Allan Drummond
6 years
First graduate student @KSamerotte accepted a faculty position. I remember the day she approached me when I was still a grad student, saying she’d like to work together when I started my lab. What a delightful, long-awaited, well-deserved, promise-filled turn of the world.
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D. Allan Drummond
4 years
Why shouldn't you try to help by pivoting your research to COVID-19? Because your pivot has current costs which almost certainly outweigh its future benefits. A brief thread with some perspective (my own perspective as a scientist) on @Y_Gilad 's important request. 1/
@Y_Gilad
Yoav Gilad
4 years
I know it's hard. You want to do something useful. It's an honest desire to help. But you can't help. Stop asking trainees to come to lab to work on your new brilliant idea of how to save humanity. Let the experts do their work. Stop 'pivoting' your research to COVID-19. Please.
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@dallandrummond
D. Allan Drummond
4 years
Faculty job interview horror stories aside, a friend & mentor told me at the time I was applying, "Enjoy it. It's the last time everyone you meet will be totally excited to hear you talk about what you're working on." Dead on.
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@dallandrummond
D. Allan Drummond
3 years
@futurebird And Lake Baikal is filled with deep creepies.
@UntamedScience
Rob Nelson
10 years
Lake Baikal Fact #2 - It contains the largest amphipods on Earth- flesh eating 3.5 inch monsters... coolio. #scichat http://t.co/Pg98k0rCk6
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@dallandrummond
D. Allan Drummond
7 years
This is a moth, Paranthrene dollii. It mimics a paper wasp well enough to fool predators, me, and the @inaturalist algorithm.
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@dallandrummond
D. Allan Drummond
7 years
What's phase separation of an RNA-binding protein good for? Sensing stress, and surviving it. Our new paper's out!
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@dallandrummond
D. Allan Drummond
4 years
Our latest: "Transient intracellular acidification regulates the core transcriptional heat shock response," overwhelmingly the work of the brilliant @ugcgccacc . More tweets when it's formatted. But already online hours after acceptance (thanks @eLife !)
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@dallandrummond
D. Allan Drummond
2 years
First keynote in the books. Honored to do it for the conference and community that has supported me and my group since my first year as an assistant prof 11 years ago: the 28th Annual Midwest Stress meeting at @NorthwesternU
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D. Allan Drummond
7 years
We have reproduced this result but only a single replicate at this time.
@Y_Gilad
Yoav Gilad
7 years
so this happened today: @dallandrummond got tenured!
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@dallandrummond
D. Allan Drummond
4 years
I made a thing.
@dadrummondart
D. Allan Drummond Art
4 years
Proudhopper (Dictyopharidae), 2020. Bronze with sterling silver wings.
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@dallandrummond
D. Allan Drummond
4 years
From a colleague: “How would we know if the math department is sheltering in place?”
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@dallandrummond
D. Allan Drummond
2 years
Congratulations to Dr. Haneul Yoo @whoisyoo on her doctorate, on winning program distinction in biochemistry and molecular biophysics @UChicagoBMB …and on the award for Best Dissertation in the Biological Sciences Division @UChicago ! 🤓🏆
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@dallandrummond
D. Allan Drummond
4 years
You've heard of elf on a shelf, now get ready for
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@dallandrummond
D. Allan Drummond
5 years
Please, @nytimes , if you want to help public understanding, please don't run an article on an alarmingly infectious fungus with a video called "Revenge of the Bacteria." Fungi are more like us than bacteria. The difference is important for helping everyone understand antibiotics.
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@dallandrummond
D. Allan Drummond
7 years
First postdoc has first faculty offer. Congrats, @ewjwallace ! What you possess comes, as they say, with great responsibility. Use it well.
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@dallandrummond
D. Allan Drummond
2 years
Yes.
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@weinberz
zara weinberg 🧪🧙🏻‍♀️
2 years
In today's Biophysics class, we're Teaching The Controversy* *is phase separation a biologically meaningful phenomenon?
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@dallandrummond
D. Allan Drummond
1 year
Still in disbelief. Sliman absorbed life and spread love so purely and intensely…so many nights of jazz, science, debates, venting, drinks, and full-body hugs where you felt he was hugging your soul. And he was. My lost brother... 💔
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@dallandrummond
D. Allan Drummond
5 years
PS: Here's a direct (detail-redacted) quote from a senior sci/editor on a study where we did controlled perturbations. "The mechanism by which [X] regulates [Y] is unclear. Without further analysis the results are essentially correlative." This is *actual nonsense*. Not uncommon.
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D. Allan Drummond
6 years
And this curious beauty: a young female Salticus scenicus, the zebra jumping spider who keeps my windowsill fly-free, in bronze and black glass, with every petal of her plumage placed separately. This is the look they give you — their vision is astonishing.
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@dallandrummond
D. Allan Drummond
5 years
No-cost extension.
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@dallandrummond
D. Allan Drummond
8 years
Busy science time, unfinished bronze pieces are piling up... #sciart
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@dallandrummond
D. Allan Drummond
4 years
This scam owes a debt to an earlier scam, “mRNA tells you enough about protein levels,” and both build on the ultimate scam: biology is simple.
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@dallandrummond
D. Allan Drummond
5 years
We establish causality through controlled perturbations. Mechanism is the "how," not the "whether". Read a bit of @yudapearl if you want a respectable introduction to causality. For now, stop causing me to lose my mind (by unknown mechanisms) by mistaking causality and mechanism.
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@dallandrummond
D. Allan Drummond
6 years
Excited to announce that we've posted a new preprint on @biorxiv by grad student @ugcgccacc (yes, she actually is going to make you translate that) where we report her remarkable discoveries about cells, heat stress, and intracellular pH. (1/6)
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D. Allan Drummond
4 years
Congratulations to @ugcgccacc who successfully defended her Ph.D. today! Mind-altering work presented with extreme clarity, centered around her discovery that the heat shock response regulated by Hsf1 has an activation pathway dependent on intracellular pH. 1/4
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@dallandrummond
D. Allan Drummond
2 years
Took an 85% pay cut to leave industry and start as a 1st year PhD student. 20 years later, as a tenured prof, I still don’t make the $ I made then (without adjusting for inflation!). Worth it. Life-defining move for me. YMMV.
@ashleyruba_phd
Ashley Ruba, PhD
2 years
"Should I do a post-doc after my PhD or go right into industry? I want to see if I can get an academic job." I grappled with this same question three years ago. Instead, I wish I would have asked myself this: "Would I pay $120,000 for the *chance* at an academic job?" 1/
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D. Allan Drummond
4 years
When your graduate advisor suggests it might be best to bin your data, it really depends which side of the Atlantic you're on.
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@dallandrummond
D. Allan Drummond
8 years
Where to start with this...
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@dallandrummond
D. Allan Drummond
3 years
Fireworks @uchicago
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D. Allan Drummond
4 years
Well, this pretty much made my year.
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@dallandrummond
D. Allan Drummond
4 years
I'm going high weight, low reps on these pull-ups.
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D. Allan Drummond
5 years
First day of 2020 (happy new year, everyone!), first day of first sabbatical in 13 years as PI. Here at @uchicago it's not automatic -- instead, many convos with trusted friends led to the request. More to share; that's one of my goals for this stretch.
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D. Allan Drummond
7 years
Scientist life choices.
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@dallandrummond
D. Allan Drummond
5 years
Come be my colleague @uchicago ! We're searching broadly for junior faculty to join us in Biochemistry & Molecular Biology. The broad search is serious: we want great minds, first and foremost. I'm excited to see what you all are up to...
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D. Allan Drummond
5 years
You created an incredible thing @OdedRechavi — kudos. Will treasure this experience watching a community find itself, learn about itself, and spread the love. You made it happen! Thank you ❤️ #physiologicalirrelevantconference
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D. Allan Drummond
4 months
@christlet @inkscape We make all our publication figures in @inkscape and have for years...no particular resources to share, I learned organically and use essentially the vanilla package, so chiming in mostly to say it's possible (and enjoyable) to do.
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D. Allan Drummond
6 years
“Huntress,” 2018, bronze and neodymium. The mantis Tenodera sinensis, with articulated raptorial hooks and shoulders, and her head mounted on magnets. 23 cm long.
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D. Allan Drummond
2 years
Out now: detailed protocols from @whoisyoo for studying chaperone dispersal of RNA-binding-protein condensates. 1/3
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D. Allan Drummond
4 years
Reupping this because someone who knows me well asked, disbelievingly, "Have you gotten R01s rejected?"
@dallandrummond
D. Allan Drummond
7 years
ND, ND, ND, ND, ND, ND, 44, ND, ND, 10.
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D. Allan Drummond
3 years
You know, was working HR job with software company in TX, kept spending spare cash on textbooks, after a few years explored possibility (with professionals) that I’d lost my mind, quit job, started grad school at 29, and here we are.
@MothProf
Dr Emily BurdfieldSteel
3 years
I am so bored of reading about biologists' childhoods (or let's be honest, boyhoods) spent running around the countryside collecting insects. Like that's nice and all, but some of us grew up in cities. Can we get some alternative biologist origin stories?
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D. Allan Drummond
6 years
“Ahhhhh...so much better. You wouldn’t believe how stuffy it is in that thing.” (After capturing this, we put him back outside to dry and start his brief singing career.) Neotibicen sp. #cicada .
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D. Allan Drummond
3 months
Article accesses after six weeks on @biorxivpreprint ... the world has truly changed.
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@dallandrummond
D. Allan Drummond
4 months
How do cells efficiently respond to stress? Transcriptional stress responses are well-known—and in our latest study, we discover that cells use biomolecular condensation to redirect translation from old to new mRNAs 1/n
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D. Allan Drummond
7 years
Lab showed up in surprise custom tees at my dept seminar -- so touched. Roton & visiting student apparently need to earn theirs...
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D. Allan Drummond
3 years
The improv comedy technique of responding "yes, and..." to your partner is actually a life/work/relationship skill with few parallels
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D. Allan Drummond
5 years
We do not need to know the mechanism of egg frying to know that heat causes eggs to fry.
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D. Allan Drummond
2 years
Congratulations to Rosalind Pan, our group’s superstar undergrad, who graduated this morning @UChicago summa cum laude and shortly starts her next chapter—grad student @Caltech ! ⭐️🥹
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D. Allan Drummond
5 years
Thanks @Y_Gilad ... #3facts5scientists 1. All the grad schools I applied to rejected me 2. I teach, but have never taken, a graduate biochemistry course 3. Most people who know I exist believe I study trilobites @alexholehouse @DannyHatters @Tanner_Lab @LabPetry @GreenLabJHMI
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D. Allan Drummond
3 years
Congratulations to our newly minted Dr. Yoo! 😎 @whoisyoo delivered a tremendous public defense today ("Chaperones remodel stress-induced biomolecular condensates"), a crystal-clear tour of her research for a planet-wide audience. 1/4
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D. Allan Drummond
3 years
Must say we've been beating this drum (IDRs are often neither necessary nor sufficient for condensation) for quite some time. It was never a sensible principle; it was more like something people hoped for. Zombie dogma. See
@549nm
Frank Xie lab
3 years
It almost becomes a dogma that intrinsic disordered region(IDR) drives biomolecular condensate formation likely through phase-separation. A new study challenges this tenet showing that IDR is dispensable for condensates but DNA binding is the culprit.
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D. Allan Drummond
4 years
I still cherish two rather abrupt dressings-down I got from two different mentors. These were not pleasant in the moment. But I trusted them, they knew what they were doing, and they were right. They put my long-term success over my short-term comfort. *Trust* was crucial.
@slavov_n
Prof. Nikolai Slavov
4 years
What are some of the most helpful things your mentors have done for you?
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D. Allan Drummond
4 years
People, reach out to the folks you admire and ask if they will Zoom with you *right now*. @PracheeAC agreed, and we had a spectacular, wide-ranging chat that can only be had with someone who's "been there." Super-meaningful. 🥃✨🥃
@PracheeAC
Prachee Avasthi 🪷
4 years
Absolutely lovely cocktail zoom with @dallandrummond to replace the derailed in-person drink we were supposed to have almost a year ago! Until next time!🍷
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D. Allan Drummond
5 years
Here's a bit from page 2 of an introductory book I thought might help me get up to speed on something. This is apparently annoyingly trivial if you have the proper training. I apparently made some incorrect life choices, and will now suffer for that. (+1 job specialization.)
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D. Allan Drummond
5 years
We study the cellular response to heat shock. It was discovered in the 60s and the mechanism behind the response remains unclear. Even the mechanism by which yeast -- single cells! -- sense heat is not yet known. But we know that heat causes the heat shock response.
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D. Allan Drummond
6 years
“Curiosity” opens Friday 12/7 6-9 pm in Seattle at Roq La Rue Gallery, 705 E Pike St. I’ll be there — come say hi and see my work at the interface of art, science, and the natural world.
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D. Allan Drummond
2 years
@stephenfloor "As far as we are aware..."
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D. Allan Drummond
3 years
How to rally physicists, mathematicians, taxonomists, and cell biologists to a common cause 🔥🔥🔥 cc: @thegridkid ❤️
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D. Allan Drummond
5 years
Absolutely fantastic news -- @HarmitMalik has been a kind of guardian angel since the beginning of my career, and I expect our nation will profit from his guidance much as as I have.
@theNASciences
National Academy of Sciences
5 years
Congratulations Harmit S. Malik @HarmitMalik of @fredhutch @HHMINEWS , newly elected #NASmember ! #NAS156 #genetics
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D. Allan Drummond
3 years
Gave a talk today and my (lovely) host said that his student was now a postdoc in the lab of my first graduate student. This is a) wonderful, and b) terrifying evidence consistent with being old. When did this happen?
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@dallandrummond
D. Allan Drummond
4 years
Video of my talk "Rethinking the cellular heat shock response" for Cellular & Protein Homeostasis series here: 35 min talk, 45 mins of Q&A! Thanks to organizers @PaoloDeLosRios @NadinathN @goloubinofflab , A+ audience, and @whoisyoo for her discoveries.
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@dallandrummond
D. Allan Drummond
6 years
My debut show opening is 6-9pm this Friday 12/7 at Roq La Rue Gallery (705 E. Pike St.) in Seattle—I’ll be there! Quite excited to show y’all what I’ve been up to. As a teaser, here is a tiny piece of a piece: half of a mitotic spindle pulling on chromosomes.
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