Christian Mosimann @chrmosimann Twitter profile

Pinned Tweet

Christian Mosimann

5 months

Delighted & grateful to see one of our #zebrafish transgenics and #pIGLET on this week's cover of @ScienceAdvances !🐽🎉 Paper here: Congrats to all involved - tweetorial update coming soon! @CUAnschutz @CUDeptofPeds @Rob_Lalonde89 @aburger2009

pIGLET: Safe harbor landing sites for reproducible and efficient transgenesis in zebrafish

Zebrafish transgenesis is advanced using validated, efficient, and reproducible landing sites.

www.science.org

Science Advances

@ScienceAdvances

5 months

Researchers have developed a transgenic technology for zebrafish that allows for the insertion of genetic material into specific locations. Learn more in this week’s issue of Science Advances:

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Last Seen Profiles

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Christian Mosimann

@chrmosimann

1 year

One of the few reasons to stick with this platform is @AuschwitzMuseum . Read their message.

Auschwitz Memorial

@AuschwitzMuseum

1 year

Failing to address the antisemitic and Holocaust denial comments that appear under our posts commemorating the victims of Auschwitz would be a disservice to their memory. We've chosen to block users who promote denial and hatred. This decision stems from our deep dedication to

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Christian Mosimann

@chrmosimann

3 years

My mom's traditional 🇨🇭 Easter eggs, stained with onion peel and hand-plucked spring herbs:

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Christian Mosimann

@chrmosimann

4 years

As undergrad, I struggled immensely with this: reading and omg understanding papers. Especially as non-native English speaker. I did develop a system that helped me back then. Bear with me it is pretty...mundane. 1/n #reading #PhDLife #PDlife #undergradlife #papers #science

Junellie Perez

@JunellieG

4 years

How do scientists just read a paper and automatically *get* it and understand everything? I'm struggling so much to read papers and it feels impossible to digest the information in them. Any tips on how to read papers??

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Christian Mosimann

@chrmosimann

2 years

Even if you are highly selective in who you follow on Twitter, make @AuschwitzMuseum a must-follow for your timeline.

Auschwitz Memorial

@AuschwitzMuseum

2 years

This year we are hoping to reach 1,5 million followers of @AuschwitzMuseum . Less than 130k is needed to reach the goal. We kindly ask you to amplify our voice. Every RT matters. You can all help us commemorate the victims, preserve memory & educate the world via social media.

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Christian Mosimann

@chrmosimann

2 years

Scale bars, everyone: #biology #imaging #Reviewer3

Stefan A.L. Weber

@StefanALWeber

6 years

One day after #EventHorizon announced their picure of a #BlackHole , we finally managed to image a #protein ring using #AFM yesterday - there is a factor of ten sextillion (10^22) between the scalebars of those two images.

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Christian Mosimann

@chrmosimann

1 year

How did fins turn into limbs? Out @Nature : our latest multi-lab/-national/-model collaboration co-led by @CarneyTomJ adds new pieces to an old #evodevo puzzle. Ready for #zebrafish , medaka, goldfish, paddlefish, frogs, lampreys, sharks, et al.? A 🧵1/18

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Christian Mosimann

@chrmosimann

4 years

If you are a PI in the US and pride yourself with having lab members from abroad: Familiarize yourself w/ process, timelines, & the crippling uncertainties behind many research visas. Know what your lab members need to do to science with/for you. #PILife #PhDLife #PDLife

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Christian Mosimann

@chrmosimann

2 years

* Shipping label: Mosimann Lab * @FedEx : Musselman Lab? Close enough. How a box of #zebrafish embryos led to our new @NSF collaboration with @MusselmanLab : IDRs, gene regulation, and #devbio ! 🧬❤️🐟⚡️ @CUAnschutz @CUDevBio @CUMedicalSchool

CU Researchers Awarded $1.3 Million National Science Foundation Grant

A misdelivered package during the pandemic leads to a partnership between Christian Mosimann and Catherine Musselman to understand mechanisms of genome regulation.

news.cuanschutz.edu

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Christian Mosimann

@chrmosimann

4 years

Lab meeting pro-tip: we added a discussion point called Screw-up of the Week™ and its surprisingly hilarious. #mosimannlabgoeswest #labmeeting #PILife

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Christian Mosimann

@chrmosimann

4 years

What part of manuscript writing do you hate the most and why is it figure legends? #askingforafriend #PILife #WFH #neverdone

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Christian Mosimann

@chrmosimann

4 years

Priding yourself with mentoring undergrads doing research in your lab? Then make them also co-authors on your papers that feature their acquired data. It's really not hard. It matters to them. And it should matter to you. @AcademicsSay #PILife #publishing #mentoring

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Christian Mosimann

@chrmosimann

8 months

Tremendously grateful for this R01 #NOA from @nih_nhlbi . ❤️🫀 We are recruiting at all levels - get in touch if you want to study early cell fate mechanisms, cardiovascular disease, enhancers, et al. @CUAnschutz in sunny Colorado! #zebrafish #CHD #devbio 🧬🐟🌄

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Christian Mosimann

@chrmosimann

2 years

Our #zebrafish pic on the cover of @DevelopmentalDy 's latest issue - styled like a back-to school photo! Congrats again Rob Lalonde, Cassie Kemmler, Fenne Riemslagh, Andy Aman, @ye_le_nna , @hannah_moran , @Susan81643382 , @parichylab , @aburger2009 . @CUDevBio

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Christian Mosimann

@chrmosimann

2 years

New preprint w/ friends on new plasmids for #zebrafish transgenesis (& #cavefish , & more!) 🐟🧬 A multi-year collab w/ @aburger2009 @kwantourage @TheLovelyLab @NicolasRohner & Affolter lab, led by Cassie Kemmler & @hannah_moran , et al. Summary🧵1/n

Next-generation plasmids for transgenesis in zebrafish and beyond

Transgenesis is an essential technique for any genetic model. Tol2-based transgenesis paired with Gateway-compatible vector collections has transformed zebrafish transgenesis with an accessible,...

www.biorxiv.org

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Christian Mosimann

@chrmosimann

8 years

Key lesson learned as junior PI: Everything takes forever, plus 6 months. #research #science #patience

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Christian Mosimann

@chrmosimann

5 years

Big shout-out to all trainees who give their, maybe first-ever, meeting talk at #TAGC20 @GeneticsGSA : - at home - possibly alone - without their mentors, colleagues, friends as support Thank you for sharing your research with all of us! We see you and we are applauding you.

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Christian Mosimann

@chrmosimann

4 years

Honored & grateful to receive the @ZDMSociety award in these trying times. The award also recognizes our amazing international trainees using #zebrafish #devbio as cardiovascular disease model, first @UZH_en & now @CUAnschutz - and our fantastic collaborators! Thx all🍾🐟!

ZDMSociety

@ZDMSociety

4 years

ZDMS would like to congratulate Christian Mosimann for receiving the 2020 ZDMS Junior Faculty Award for Excellence!

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Christian Mosimann

@chrmosimann

1 year

He exists in real life! Honored to meet @ZebrafishRock legend Kevin Thiessen, the central driver connecting the #zebrafish community at all levels. Thank you for all you do. Don't miss his award lecture #2023SDB tomorrow!

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Christian Mosimann

@chrmosimann

4 years

PSA: #collaborate #coordinate #PILife #zebrafish

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Christian Mosimann

@chrmosimann

1 year

Out now: our Brachyury enhancer extravaganza by @aburger2009 & @KozmikLab , w/ @EKFarley @MaxYunLab @AxelVisel @m_osterwalder @LiciaSelleri @FishEvoDevoGeno & teams! Conserved enhancers control notochord expression of vertebrate Brachyury Congrats all!

Conserved enhancers control notochord expression of vertebrate Brachyury

Nature Communications - This study identifies three conserved shadow enhancers (T3, C, I) regulating notochord expression of Brachyury across vertebrates using genomic data, transgenic assays, and...

www.nature.com

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Christian Mosimann

@chrmosimann

4 years

Happy our review on the lateral plate mesoderm is out @Dev_journal , with @karin_prummel & @Susan81643382 (open access). Our first attempt at reviewing the fascinating, wacky, complex biology as Development at a Glance with poster! #devbio #evodevo

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Christian Mosimann

@chrmosimann

11 months

How can we reproducibly make high-quality transgenics in #zebrafish ? 🧬🐟 Welcome pIGLET, two first phC31 integrase-based safe harbor sites & vector toolkit for broad transgenesis applications: Congrats to @Rob_Lalonde89 & all! 🧵to meet pIGLET 🐽:

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Christian Mosimann

@chrmosimann

2 years

Our lab turns 10 today! 🧬🐟🌍🌎😳🥳 Grateful to all our fabulous past and present trainees, collaborators, friends, colleagues @CUAnschutz @CUDevBio - and our #zebrafish . #PILife #devbio #evodevo #CHD (not a genetic mosaic, but...)

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Christian Mosimann

@chrmosimann

4 years

Cerulean and mCherry brighten up the day (and the mesoderm): LPM & notochord reporter combo imaged by @hannah_moran @CUDevBio @CUAnschutz : #zebrafish #transgenics #imaging #weCUdevbio #devbio #evodevo

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Christian Mosimann

@chrmosimann

6 years

The Mosimann lab is moving! 🌍->🌎 Happy to announce my appointment as Johnson Endowed Chair in #Heart Development Research @CUMedicalSchool : We & our #zebrafish will join the growing @CUAnschutz #DevBio & #Cardiology community this summer - Denver, here we come! 🐟🐣❤️🧬

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Christian Mosimann

@chrmosimann

2 years

How is Brachyury expression controlled in the mammalian notochord? In our collaborative @biorxivpreprint , we address this decades-old #devbio question - & found a deeply conserved surprise. A 🧵1/n

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Christian Mosimann

@chrmosimann

4 years

Excited to share our new @biorxivpreprint , led by @karin_prummel @CrowellHL & international friends/collaborators: "Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma" #zebrafish #devbio #mesothelioma #scRNAseq #SPIM 🐟🐁🧑‍🤝‍🧑🎾

Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

The mesothelium forms epithelial membranes that line the bodies cavities and surround the internal organs. Mesothelia widely contribute to organ homeostasis and regeneration, and their dysregulation...

www.biorxiv.org

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Christian Mosimann

@chrmosimann

1 year

How it (the week) started... (one for the lab, one for the #zebrafish community)

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Christian Mosimann

@chrmosimann

4 years

Psst...we'll have postdoc and technician positions available in the near future...come join us @CUAnschutz @CUDevBio to study early cell fate control, cardiovascular #devbio , and #zebrafish imaging. Ping me if interested! #zebrafishjobs #mosimannlabgoeswest #evodevo #SPIM

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Christian Mosimann

@chrmosimann

4 years

Our lab turns 8 today: Grateful to all amazing past & present lab members, collaborators, and science friends around the world - onwards to the next 8! #mosimannlabgoeswest #zebrafish @CUDevBio @CUAnschutz #weCUdevbio #devbio #evodevo (pandemic bday in a fish lab:)

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Christian Mosimann

@chrmosimann

2 years

Big congrats to our (Twitter-less) postdoc Robert Lalonde @DevBioPostDocs @CUDevBio for receiving his K99 NoA @nih_nhlbi . 🐟🧬❤️🥂 Stand by for some cool #zebrafish #transgenics to drop in the near future! @TBX4_Life #CHD #devbio @CUAnschutz #PILife

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Christian Mosimann

@chrmosimann

1 year

Choosing NOT to cite other labs' work (that is clearly of relevance) does not make a paper more 'novel'. #devbio

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Christian Mosimann

@chrmosimann

4 years

Monday motivation - #zebrafish embryo showing off the beauty and complexity of early #devbio . (pic credit Frederike Riemslagh @DevBioPostDocs @CUDevBio @CUAnschutz ) #weCUdevbio #transgenics #imaging #mosimannlabgoeswest

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Christian Mosimann

@chrmosimann

3 years

Chairing the tech session at an international conference, like: #IZFC2021 #zebrafish #devbio #virtualmeetings #WFH #PILife #mosimannlabgoeswest

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Christian Mosimann

@chrmosimann

6 years

Out @NatureComms : "Continuous addition of progenitors forms the cardiac ventricle in #zebrafish " w/ @FelkerAnastasia @karin_prummel @Anne_M_Merks @huiskenlab & @PanakovaLab ! #heart #devbio #SPIM @UZH_Science @MDC_Berlin @mpicbg @Morgridge_Inst

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Christian Mosimann

@chrmosimann

3 years

#Zebrafishjobs : we have several postdoc and technician openings in our lab @CUAnschutz @CUDevBio ! Lab info and contact here - spread the word 🧬❤️🐟: #PostdocJobs #AcademicJobs #transgenics #imaging #devbio #evodevo #zebrafish

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Christian Mosimann

@chrmosimann

7 months

As every year (and once more from a distance 🌍->🌎): My 🇬🇷mom's traditional 🇨🇭Easter eggs, stained with onion peel and hand-plucked spring herbs. Happy Easter! Hug your families.

Christian Mosimann

@chrmosimann

2 years

This year's batch of traditional 🇨🇭Easter eggs dyed with onion peel and herbs by my 🇬🇷mom:

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Christian Mosimann

@chrmosimann

2 years

Problem: "I have a hard time starting to write my paper!" Partial solution: use a simple PaperTemplate.doc to counter Staring-At-The-Empty-Page Syndrome. Add meeting abstract, methods snippets, meeting notes...and things start to happen. #PILife #writing

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Christian Mosimann

@chrmosimann

2 years

This year's batch of traditional 🇨🇭Easter eggs dyed with onion peel and herbs by my 🇬🇷mom:

Christian Mosimann

@chrmosimann

3 years

My mom's traditional 🇨🇭 Easter eggs, stained with onion peel and hand-plucked spring herbs:

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Christian Mosimann

@chrmosimann

4 years

Traditional Swiss Easter eggs (pic from my mom who I have not seen in almost 2 years): #devbio 🥚🥚🥚🐰

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Christian Mosimann

@chrmosimann

4 years

Best way to find typos is to hit submit: micro-update (corrected figure panel label🤭) on our latest @biorxivpreprint on Hand2 in mesothelial progenitors and its re-activation in #mesothelioma : #devbio #collaborate #zebrafish #SPIM #LSM

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Christian Mosimann

@chrmosimann

5 years

Out @NatureComms : "A conserved regulatory program initiates lateral plate mesoderm emergence across chordates" Led by @karin_prummel , w/ @huiskenlab @KozmikLab @BronnerLab , @lionlchristiaen & al! #zebrafish #devbio #zebrafish #evodevo #devbio #collaborate

A conserved regulatory program initiates lateral plate mesoderm emergence across chordates

Nature Communications - Numerous tissues are derived from the lateral plate mesoderm (LPM) but how this is specified is unclear. Here, the authors identify a pan-LPM reporter activity found in the...

www.nature.com

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Christian Mosimann

@chrmosimann

3 years

Out now, our multi-collaborator work on mesothelium development and how #devbio can inform about #mesothelioma : #Zebrafish , scRNA-seq, #SPIM , transgenics, mutants, #mice , Cre/lox, tumor path, with fantastic collaborators & friends. 🌎🌍🐟🐭🩺🧬 @karin_prummel 's tweetorial here:

Karin D. Prummel

@karin_prummel

3 years

Our paper on the mesothelium origins is out in @NatureComms !! I'm very happy to unroll here our most exciting insights 🐟🐭👩🧑🧬🔬 #zebrafish #devbio #mesothelium #mesothelioma @UZH_en @CUAnschutz @CUDevBio 1/15

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Christian Mosimann

@chrmosimann

9 months

OTD 11 years ago, as postdoc. I vaguely remember revision anxiety, job application stress, constructs not working, visa worries, sleepless nights, freezing apartment, et al. But I clearly remember this peaceful moment. Time flies. Pick your memories. #AcademicParenting #PILife

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Christian Mosimann

@chrmosimann

2 years

Interested in gaining research experience in devbio & disease modeling using #zebrafish , live imaging, transgenics, etc. with us? Open Lab Technician position at our lab @CUAnschutz @cudevbio - DM for more info!

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Christian Mosimann

@chrmosimann

3 years

#PostDocJobs : interested cardiovascular & blood #devbio , congenital heart disease, early mesoderm fates, with a hint of #evodevo , using #zebrafish ? We're looking for #postdocs to join our team @CUAnschutz @CUDevBio ! DM or email me, details here:

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Christian Mosimann

@chrmosimann

2 years

Our next-gen plasmids for #zebrafish transgenesis et al. are out @Dev_journal - congrats again to all involved, & thx for the reviewer feedback! Have you tried any plasmids yet? #Zebrafish #Transgenics #AlwaysBeCloning

Next-generation plasmids for transgenesis in zebrafish and beyond

Summary: The generation, validation, and application of several new plasmid vectors suitable for transgenesis in zebrafish and other species.

journals.biologists.com

Christian Mosimann

@chrmosimann

2 years

New preprint w/ friends on new plasmids for #zebrafish transgenesis (& #cavefish , & more!) 🐟🧬 A multi-year collab w/ @aburger2009 @kwantourage @TheLovelyLab @NicolasRohner & Affolter lab, led by Cassie Kemmler & @hannah_moran , et al. Summary🧵1/n

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Christian Mosimann

@chrmosimann

3 years

Is Fibroblast Friday a thing? (pic by Robert Lalonde, serendipitous fin fibroblast expression in #zebrafish while enhancer-testing with mCerulean): #devbio #evodevo #transgenics

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Christian Mosimann

@chrmosimann

8 months

Our lab turns 11 today!?! 🎂 #PILife #zebrafish

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Christian Mosimann

@chrmosimann

3 years

Things that bring a smile when walking through the lab: literal (phone) screen shot of a dataset emerging from the confocal (ubi:Switch & new creERT2 driver, 16 dpf). #zebrafish #fluorescence #lablife #PILife #mosimannlabgoeswest @CUDevBio (pic credit Frederike Riemslagh)

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Christian Mosimann

@chrmosimann

3 years

Honored to have been nominated & elected to contribute to @InfoIzfs as US/Canada representative - and in such great company! 🙏🐟❤️🧬 #zebrafish #devbio #evodevo #ModelSystemsStillMatter

IZFS

@InfoIzfs

3 years

THE RESULTS ARE IN! Congratulations to the newly elected IZFS Board Members: Drs. Whitlock (President-Elect), Kwan (Secretary), Sadler-Edepli (Asia/Pacific), Whitfield (Europe), Neuhauss (Europe), Bruce (US/Canada), & Mosimann (US/Canada).

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Christian Mosimann

@chrmosimann

4 years

Even when focusing on #teammesoderm , we at times cannot avoid noticing ectodermal lineages. Because #devbio is beautiful. Double-transgenic #zebrafish carrying reporters for rhombomere enhancers from fish (eGFP) & human (Cerulean). More tk! (w/ @aburger2009 & @AKocere )

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Christian Mosimann

@chrmosimann

3 years

PSA: ~8% of people have a form of color vision deficiency, most-prominently red-green. Also scientists. We cannot just "try harder" to appreciate green-red lookup tables used in microscopy images. Or red text "highlighting". @WeTheColorBlind #devbio #zebrafish #IZFC2021

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Christian Mosimann

@chrmosimann

4 years

Pandemic lab tip: I started a dedicated biweekly "Beers & Careers™" hour with our lab's postdocs (still Zoom, beer not mandatory) @CUDevBio . We chat/gossip postdoc life, career trajectories, mundanities, et al. Awesome interactive experience! #PILife #PDLife #zebrafish

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Christian Mosimann

@chrmosimann

2 years

The last 5% of a manuscript always takes 10000% of the effort. #PILife #Publishing #AlwaysBeWriting #Collaborate #devbio #zebrafish #zerbafish #MathIsHard

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Christian Mosimann

@chrmosimann

4 years

Rollercoaster week continues - our first germline transmission of a new Tol2 reporter transgene here at @CUAnschutz . Great job by Cassie Kemmler, @hannah_moran & @aburger2009 - this means we still got it :)! #zebrafish #devbio #evodevo #Tol2 #transgenes #mosimannlabgoeswest

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Christian Mosimann

@chrmosimann

3 years

Observing a new cre driver for the first time (Renaissance painting-style), w/ @ye_le_nna @hannah_moran & Rob Lalonde: #PILife #zebrafish #transgenics #imaging #MosimannLabGoesWest #devbio #weCUdevbio @CUDevBio @DevBioPostDocs @CSD_CUAMC

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Christian Mosimann

@chrmosimann

1 year

Honored to join the @SocDevBio board as South West rep - and congrats to all newly elected members/colleagues! #devbio #evodevo #collaborate

Society for Developmental Biology

@SocDevBio

1 year

Congrats to the newly elected SDB Board Members! President-elect: Carole LaBonne Treasurer: Danelle Devenport PUI Rep: Olivia George Postdoc Trainee Rep: Martha Echevarria-Andino MW Rep: Sharon Amacher NE Rep: Carrie Adler SW Rep: Christian Mosimann

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Christian Mosimann

@chrmosimann

9 months

A heart-felt #FluorescenceFriday from our #zebrafish to you(rs)! 🧬🫀🐟💚💜 (pic credit @Rob_Lalonde89 & @hannah_moran @CUAnschutz @CUDevBio ) #devbio #transgenics

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Christian Mosimann

@chrmosimann

8 months

PSA: If you are getting plasmids shared on @Addgene , cite the *original publication* in your paper. 🧬 ...and not just the Addgene number. People made these tools. And documenting sources and applications is critical for funding, reproducibility, and more.

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Christian Mosimann

@chrmosimann

5 years

The Mosimann lab turns 7! 🐟🧬🐣 Est. 03/01/2013 with Anastasia Felker & Christopher Hess as first PhD students @UZH_en . Biggest thx to all alumni, lab members @CUAnschutz , our awesome collaborators & colleagues - off to the next 7! #mosimannlabgoeswest #zebrafish #PILife

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Christian Mosimann

@chrmosimann

4 years

First publication from the lab with @CUAnschutz affiliation accepted! Lateral plate mesoderm goodness coming soon & schematics col(u)ored in "LPM Green" ;). ⚾️🎾 Congrats @karin_prummel & Susan Nieuwenhuize! #devbio #evodevo #mosimannlabgoeswest

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Christian Mosimann

@chrmosimann

3 years

@cterminiPHD Block off one day per week where you don't schedule any meetings. I do this on Thursdays. Needs some effort to keep it free, but worth it. Opens up time for interacting with the lab, jump on the microscope, write, etc.

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Christian Mosimann

@chrmosimann

1 year

Morula. #devbio #embryogenesis

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Christian Mosimann

@chrmosimann

4 years

What do #zebrafish tell us about early heart #devbio ? 🐟🫀⚾️ Our review write-up w/ Cassie Kemmler, Fenne Riemslagh, @hannah_moran @CUDevBio @CUAnschutz "From Stripes to a Beating Heart: Early Cardiac Development in Zebrafish" @JCDD_MDPI #mdpijcdd

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Christian Mosimann

@chrmosimann

4 years

I'm not saying it's wrong, but...is there anything that we learn from the GO term "biological process"? #bioinformatics #data #PILife #WFH #devbio

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Christian Mosimann

@chrmosimann

4 years

-Me (grant-writing): Do you think... -Spouse (grant-writing): Beer? -Me: ...don't we we still need to continue with... -Spouse (who is also German): *opens beer* No. #PILife #writing #stillhatingAim2

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Christian Mosimann

@chrmosimann

3 years

Lab meeting today: #PIlife #zebrafish

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Christian Mosimann

@chrmosimann

6 years

#IZFC2018 Twitter feeders! #zebrafish

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Christian Mosimann

@chrmosimann

5 years

#Zebrafish phenotype codes in the lab: - "normal" - "delayed" - "a bit messed up" and my fav - "run over by a truck" Any additions from your lab? #devbio #mutants #CRISPR #PIlife

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Christian Mosimann

@chrmosimann

2 years

Delighted to host the one and only @BlockInTheBack for her seminar visit @CUAnschutz @CSD_CUAMC today! Prepping for an exciting day of #zebrafish , #devbio , #morphogenesis , #transgenes , et al:

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Christian Mosimann

@chrmosimann

4 years

Walking out of rhe liquor store with a bottle of bubbly and having people cheer at me.

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Christian Mosimann

@chrmosimann

2 years

Bivalent Covid boosters for the parents loaded...and flu shots for all! #GetVaccinated #GetYourShots #FluShots @aburger2009

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Christian Mosimann

@chrmosimann

10 months

Fellow #zebrafish PIs: looking to get started with pIGLET and attending #SCZI2024 ? @Rob_Lalonde89 prepared pIGLET vector starter packs that @aburger2009 and I will bring along! 🐽 DM if interested to estimate how many we need - looking forward to seeing everyone in Asilomar!

Christian Mosimann

@chrmosimann

11 months

How can we reproducibly make high-quality transgenics in #zebrafish ? 🧬🐟 Welcome pIGLET, two first phC31 integrase-based safe harbor sites & vector toolkit for broad transgenesis applications: Congrats to @Rob_Lalonde89 & all! 🧵to meet pIGLET 🐽:

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Christian Mosimann

@chrmosimann

3 years

Papers. This is how they all start. There is usually no sudden stroke of inspiration or a defining kick-off. You have to sit down and start. Do the work. Purpose-driven mundanity. Even if it sucks. #PILife #writing #EmptyPage #WFH #Monday #MundanityOfExcellence

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Christian Mosimann

@chrmosimann

2 years

Christine Thisse acknowledging @ZebrafishRock @kdthiessen in her Streisinger Award lecture #izfs2022 - capping off a memorable recap of her & the late Bernard Thisse's #zebrafish #devbio trajectory.

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Christian Mosimann

@chrmosimann

3 years

@rburdine1 To get more papers discussed, we do NanoJournalClub™ as part of our pre-progress report discussion. One lab member picks a paper and presents 3 slides: 1. Title & authors, outlining who's involved 2. Walk-through of their favorite figure 3. Take-home points 5 min. We love it.

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Christian Mosimann

@chrmosimann

4 years

#devbio #RIPLewisWolpert

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Christian Mosimann

@chrmosimann

4 years

Genetic lineage tracing in #zebrafish ? Sure, we do that, too! (early lateral plate-fated progenitors traced from early gastrulation (magenta); pic credit to Rob Lalonde & Fenne Riemslagh) #devbio #weCUdevbio @CUAnschutz @CUDevBio

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Christian Mosimann

@chrmosimann

5 years

...and we're live @CUAnschutz : tackling admin and lab organization w/ @aburger2009 and Cassie Kemmler, our first Colorado addition! #mosimannlabgoeswest #zebrafish #devbio

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Christian Mosimann

@chrmosimann

4 years

In pink, I labeled key questions and take-home messages. If done correctly, you can look at pink sentences alone and recap the whole paper. Peo-rip: first and last sentences of paragraphs often are pink sentences. Pro-tip 2: write papers that have pink sentences. 3/n

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Christian Mosimann

@chrmosimann

1 year

The official tea of scientific conferences? "I have more of a *constant comment* than a question...". #ZDM16

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Christian Mosimann

@chrmosimann

3 years

Excitement & smiles all around as our last #devbio , #evodevo , & #zebrafish tool abstracts are submitted for the 2022 @SocDevBio @EvoDevoPanAm meeting in Vancouver! 🎉🎓 Fingers crossed we all manage to make an appearance...😷✈️ @CUDevBio @CUAnschutz #MesodermIsStillCool

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Christian Mosimann

@chrmosimann

1 year

I'll see myself out. #devbio #evodevo

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Christian Mosimann

@chrmosimann

3 years

The best part about writing papers and grants is to discover papers published years ago that you should have already read *years ago*. #PILife #writing #HardToKeepUp

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Christian Mosimann

@chrmosimann

4 years

Today, I learned my lab started a Gel Wall of Fame/Shame. Exhibit A (I have no further info): #PILife #cloning #clowning #PCR #weCUdevbio #zebrafish #WFH

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Christian Mosimann

@chrmosimann

6 years

Psst...the Mosimann lab will have #Postdoc openings @CUAnschutz @CUMedicalSchool ! 🧬🐟❤️🌄 Join us in Denver for transgenics, #SPIM , #enhancers , cardiovascular disease models, et al. pls retweet - official ads soon! #zebrafish #zebrafishjobs #devbio #evodevo #mosimannlabgoeswest

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Christian Mosimann

@chrmosimann

3 years

Looking at you, labs who don't include undergrads and techs as authors on papers due to lack of "intellectual contribution" (but you still love to use their figures, right?):

Jason Rasgon

@vectorgen

3 years

"Technical contributions" ARE "Intellectual contributions". That's it. That's the Tweet.

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Christian Mosimann

@chrmosimann

8 months

#FluorescenceFriday : stress-testing pIGLET. krtt19e:EGFP in our #zebrafish pIGLET24b landing site. Basal epidermis-marking krtt19 reporters are notoriously position effect-sensitive = tedious founder screening with Tol2. pIGLET works right away!🐽 (line & pics @Rob_Lalonde89 )

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Christian Mosimann

@chrmosimann

4 years

Happy first day of spring with colorful lineage-labeled #zebrafish hearts (pic credit @hannah_moran @CUAnschutz @ChildrensColo ):

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Christian Mosimann

@chrmosimann

3 years

When you get a personalized lab coat and actually wear it in the lab (for pics): #PIlife #labcoat #weCUdevbio #devbio #zebrafish #zerbafish #IShouldBeWriting @CUDevBio @CUAnschutz

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Christian Mosimann

@chrmosimann

5 years

#Easter week in times of #StayAtHome : Traditional Swiss🇨🇭 Easter eggs, imprinted with herbs & dyed w/ boiled onion peel. Done by my mom🇬🇷 recipe of my late grandma. A childhood memory, shared across two continents. Happy Easter! #SocialDistancing @SwissEmbassyUSA

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Christian Mosimann

@chrmosimann

1 year

Two things make Twitter bearable and a net-positive experience: 1) Blocking/muting all sorts of accounts and keywords. 2) Following accounts like @EM_RESUS . A service to all of us. Follow him.

Sam Ghali, M.D.

@EM_RESUS

1 year

Hi, ER Doc here. I use this account to teach people about medical emergencies. It’s my birthday today and I’m hoping to hit 400K followers to be able to reach more people. Can I get some follows and retweets to help me get there?

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Christian Mosimann

@chrmosimann

6 years

Looking for a postdoc in #zebrafish , #devbio , cardiac dev & disease models, trx regulation, enhancers, #SPIM /live imaging? Come join us in Colorado @CUAnschutz ! Pls RT; DM, email for more info. #mosimannlabgoeswest 🐟🧬❤️ Offical ad & application link:

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Christian Mosimann

@chrmosimann

5 years

@lab_shenanigans

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Christian Mosimann

@chrmosimann

3 years

Remarks on faculty job searches (as 'tis the season): Chances are, as a faculty candidate you apply to several job ads. Dozens. More. You wait. You hope. (quick thread) 1/n #PILife #PDLife #AcademicJobs

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Christian Mosimann

@chrmosimann

1 year

#2023SDB has begun - w/ the satellite symposium: "Outside of Exomes: Enhancers in Development and Cogenital Disorders" chaired by @aburger2009 & @evgenykvon ! #devbio #evodevo

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Christian Mosimann

@chrmosimann

5 years

🎉🥳Good news in these crazy times 🥳🎉: Congrats to @karin_prummel for being awarded the @UZH_Science faculty distinction for her PhD thesis - proud of you! 🎓🍾 More science from Karin et al. coming soon! 🎏 @CUAnschutz #zebrafish #devbio #evodevo

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Christian Mosimann

@chrmosimann

4 years

Out @biorxivpreprint , our long-term collaboration with Anna Jaźwińska's lab @unifrBiology : "Persistent ventricle partitioning in the adult zebrafish heart" Led by Catherine Pfefferli & @hannah_moran , w/ @FelkerAnastasia #zebrafish #devbio #evodevo 1/7

Persistent ventricle partitioning in the adult zebrafish heart

The vertebrate heart integrates cells from the early-differentiating first heart field (FHF) and the later-differentiating second heart field (SHF) emerging from the lateral plate mesoderm. In...

www.biorxiv.org

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Christian Mosimann

@chrmosimann

3 years

Holiday🎄read if you enjoy Cre/lox genetics in #zebrafish - our latest @biorxivpreprint led by Rob Lalonde @DevBioPostDocs , @aburger2009 @CUDevBio , w/ @parichylab : "Heterogeneity and genomic loci of ubiquitous Cre reporter transgenes in zebrafish" 🧵1/n

Heterogeneity and genomic loci of ubiquitous Cre reporter transgenes in zebrafish

The most-common strategy for zebrafish Cre/ lox -mediated lineage labeling experiments combines ubiquitously expressed, lox -based Switch reporter transgenes with tissue-specific Cre or 4-OH-Tamoxi...

www.biorxiv.org

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