Alex Mathew @alxmthew Twitter profile

Last Seen Profiles

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Alex Mathew

@alxmthew

3 months

just got accepted to the @siliconvalleyf !!! who should i see in sf??? when i turn 18, @_TheResidency you're next ;)

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Alex Mathew

@alxmthew

2 months

thank you @DStrachman for the @1517fund Medici grant work $1k! you are a wonderful human being and i appreciate you're generosity and wisdom. i'm pumped to work on my ai mental health plushies for @serenityso_hq

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Alex Mathew

@alxmthew

2 months

missing this bridge already

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Alex Mathew

@alxmthew

2 months

in sf rn for the @siliconvalleyf who can i meet up with? just went to newmark and currently at @Apple !

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Alex Mathew

@alxmthew

4 months

i can’t tell you how cool @_buildspace is please apply to @_nightsweekends s5: i’m building the first ai mental health companion (right now in a squishmallow form!) for any creative ambitious person out there, you can gain sm from this community!

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Alex Mathew

@alxmthew

4 months

@cory @reply here’s my website:

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Alex Mathew

@alxmthew

2 months

the 44 montgomery wework. the sf locals get it. @siliconvalleyf #SanFrancisco #sf #tech

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Alex Mathew

@alxmthew

4 months

i’ve got some buddy passes for s5 @_nightsweekends you can build any project you want! i’m building serenity, the world’s first ai mental health companion dm me :) cc: @_buildspace

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Alex Mathew

@alxmthew

3 months

w3 update for @_buildspace @_nightsweekends @FarzaTV @stavanpatel was badly sick last week but now we up and attem again 💪🏾💪🏾💪🏾

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Alex Mathew

@alxmthew

2 months

the dream ❤️ see you in two years 🤞🏾 @Stanford @siliconvalleyf

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Alex Mathew

@alxmthew

3 months

who knows what’s coming next? cc: @_buildspace @_nightsweekends

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Alex Mathew

@alxmthew

3 months

hello! finished my toy for @_buildspace @_nightsweekends and it's a simple gpt. try it out here: (no, you don't need gpt+) i honestly spent so long iterating with my friends' feedback and adding insights from research papers i read! lmk what you think.

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Alex Mathew

@alxmthew

3 months

i had the most amazing time in toronto at @CollisionHQ @tksworldhq has the most amazing community and the people i met irl were the coolest, most ambitious people i've ever talked to. thank you, for making this a wonderful experience <3

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Alex Mathew

@alxmthew

4 months

day 4! what i’ve been doing: - meeting amazing ppl at @CollisionHQ - switching from GPT extension to using gemini api - building the web app w react and vercel - sketching out ideas for videos - talking to potential investors @_buildspace

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Alex Mathew

@alxmthew

1 month

just applied to an @evm_capital microgrant! if you're an ambitious person building something really cool, check them out!!!!!

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Alex Mathew

@alxmthew

2 months

thanks for speaking at mbc biolabs @martintrevor_ ! you and is so inspiring <3

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Alex Mathew

@alxmthew

3 months

psst

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Alex Mathew

@alxmthew

13 days

Your brain cycles through different wave patterns throughout the day. High Beta waves help with focus, but when they’re overactive, they can trigger anxiety. Balancing your brain waves with meditation or even nature walks can reduce stress and improve mental clarity.

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Alex Mathew

@alxmthew

3 months

hey there. do you like the idea of stuffed animal mental health friends? if so, try out this first version: ! if you're SUPER duper interested, comment down below and lmk what you think! still working on the first hardware version too :)

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Alex Mathew

@alxmthew

3 months

try out my toy for serenity! upload your journal entries or just talk to serenity like normal and feel 10x better after chatting afterwards cc: @_buildspace

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Alex Mathew

@alxmthew

4 months

also, no this isn’t another stupid ChatGPT wrapper going to be fine tuning my own llms once i get a new laptop in t-minus one week still in the beta stage of this product :-)

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Alex Mathew

@alxmthew

17 days

gratitude literally rewires your brain—boosting dopamine, reducing stress, and increasing positivity. specific, repeated practice is key. over time, appreciating specific parts of your life reshape your brain’s emotional circuits, reducing anxiety/fear & improving well-being.

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Alex Mathew

@alxmthew

2 months

thank you @siliconvalleyf for this amazing opportunity to meet some fantastic biotech founders and scientists

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Alex Mathew

@alxmthew

18 days

depression often shows up as: 1. hopelessness & low self-esteem 2. low energy, loss of sleep & appetite yes, there are variations BUT knowing this, LLMs can provide personalized, actionable advice based on surveys like these

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Alex Mathew

@alxmthew

2 months

“One day you will realize that happiness is not what your house looks like, but how you love the people within its walls. Happiness is not finding success by a certain time, but finding something you love so much time itself seems to disappear...

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Alex Mathew

@alxmthew

14 days

1/7 🧠 How social media REWIRES our brain and what we can do about it. This 🧵will CHANGE the way you view social media.

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Alex Mathew

@alxmthew

2 months

@NilPartners @DStrachman @1517fund @serenityso_hq 🤝🏾🤝🏾🤝🏾

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Alex Mathew

@alxmthew

14 days

3/7 🎰 Welcome to the Social Media Casino Endless scrolling isn't an accident – it's design. Unpredictable rewards keep teens glued to their screens, chasing the next hit of validation. Sound familiar? It should. It's how slot machines work.

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Alex Mathew

@alxmthew

6 months

i hope all my friends and i can have conversations like @lexfridman in the future

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Alex Mathew

@alxmthew

2 months

you can be the master of your fate, you can be the captain of your soul, but you have to realize that life is coming from you not at you, and that takes time - Timothee Chalamet

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Alex Mathew

@alxmthew

15 days

🧵 1/ What if I told you that eating disorders, self-harm, and addiction all have the same root cause? It’s not just mental—it’s in your brain’s reward system. The connection might be closer than you think. Let’s break it down. ⬇️

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Alex Mathew

@alxmthew

1 year

@roote_ @tksworldhq amazing graphic!

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Alex Mathew

@alxmthew

1 year

learning stoicism with @tksworldhq ! i love how the intro video described stoics with nelson mandela being a great example!

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Alex Mathew

@alxmthew

1 year

@tksworldhq stoic indifference is accepting what is out of your control. realize that there is preferred stoic indifference (i would prefer to be rich than poor) but i am content with what i have now.

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Alex Mathew

@alxmthew

12 days

🧠 MENTAL HEALTH AND NEUROTRANSMITTERS MEGATHREAD 🧠 Neurotransmitters are chemical messengers in the brain that influence everything from mood to motivation. Imbalances can significantly impact mental health. Let’s dive into the key players 👇

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Alex Mathew

@alxmthew

1 month

@evm_capital p.s. i applied with @plushies_so . i am building ai mental health plushies for pre-teens and teens and if you're interested check out my website !

Serenity Plushies

AI-powered stuffed animals for pre-teens and teens.

plushies.so

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Alex Mathew

@alxmthew

14 days

5/7 📊 The Ugly Truth in Numbers: According to : - 64% exposed to hate (daily digital poison) - 46% feel worse about themselves (self-esteem on life support)

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Alex Mathew

@alxmthew

3 months

not till we are lost, in other words not till we have lost the world, do we begin to find ourselves, and realize where we are and the infinite extent of our relations. - henry david thoreau

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Alex Mathew

@alxmthew

11 days

The gut-brain connection is real! Most serotonin is actually produced in your digestive system, not your brain. This means your diet and gut health could be impacting your mood more than you think.

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Alex Mathew

@alxmthew

3 months

@cory interning @ & @BioBQ_meat

Athena EdTech | ai tutor

At Athena EdTech, we've created personal AI tutors, so teachers can focus on human learning, and the machine takes care of test prep.

www.athena-edtech.com

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Alex Mathew

@alxmthew

4 months

@cory @reply here are some pics of my work and some links to projects!

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Alex Mathew

@alxmthew

2 months

@aridutilh @DStrachman @1517fund @serenityso_hq thank you! just applied to merge

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Alex Mathew

@alxmthew

4 months

@_nightsweekends @_buildspace see you soon! i’ll be shipping every week :))

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Alex Mathew

@alxmthew

14 days

7/7 💙 AI in Teen Mental Health LLMs aren't just chatbots. Imagine AI-powered plushies providing 24/7 mental health support for teens. Combining this with established psychotherapies, we're reimagining emotional support. The future of mental health? It might just be cuddly.

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Alex Mathew

@alxmthew

14 days

4/7 🎭 Identity Crisis 2.0 1 teen. 5 platforms. 10 personas. "Be yourself," they say. But WHICH self? This digital identity juggling act is leaving teens confused, stressed, and lost.

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Alex Mathew

@alxmthew

2 months

3.5hrs a day on your phone is 60 days a year.

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Alex Mathew

@alxmthew

4 months

one of the most beautiful and reassuring things i’ve seen all week @paulg

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Alex Mathew

@alxmthew

3 months

@erick_turro @siliconvalleyf @_TheResidency much appreciated erick & team ❤️!

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Alex Mathew

@alxmthew

12 days

Neurochemistry & brain waves are powerfully linked to mental health: Low serotonin ➡️ fewer alpha waves ➡️ depression High norepinephrine ➡️ excess beta waves ➡️ anxiety Balancing neurotransmitters can stabilize brain waves, enhancing mood, focus & relaxation. 🌟🧘‍♂️

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Alex Mathew

@alxmthew

4 months

@FarzaTV @_buildspace hindi pop goes crazy. this is gonna be fire

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Alex Mathew

@alxmthew

15 days

3/ In Anorexia Nervosa (AN), starvation triggers dopamine release, creating a false sense of “reward.” This rewires the brain to associate restriction with pleasure. The ventral striatum and hypothalamus are key players in this process. (Source: JAMA Psychiatry)

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Alex Mathew

@alxmthew

15 days

4/ But it’s not just Anorexia. In Bulimia Nervosa (BN), binge eating can cause dopamine dysregulation, requiring more extreme behaviors to achieve the same dopamine hit—similar to substance addiction or binge-watching TV. (Sound familiar?)

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Alex Mathew

@alxmthew

2 months

@zfellows_ mental health plushies

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Alex Mathew

@alxmthew

12 days

8⃣ Medications help restore neurotransmitter balance: SSRIs/SNRIs boost serotonin & norepinephrine for depression/anxiety Benzodiazepines enhance GABA for anxiety Stimulants increase dopamine for ADHD Antipsychotics block dopamine in schizophrenia

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Alex Mathew

@alxmthew

11 months

@tksworldhq neuralink, by elon musk, aims to merge the human brain with ai. one cool application is restoring mobility for paralyzed individuals. one day a neuralink implant will allow the brain and devices to connect, allowing paralyzed ppl to control prosthetics with their thoughts.

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Alex Mathew

@alxmthew

1 year

check out my article about ai and how it is revolutionizing glioblastoma care here:

How AI is Revolutionizing Glioblastoma Care

Table of contents

medium.com

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Alex Mathew

@alxmthew

15 days

Sources: , , , ,

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Alex Mathew

@alxmthew

11 months

@tksworldhq nad+ & nmn are tiny helpers in our cells! they're like vitamins that give our mitochondria a boost. when we take them as supplements, they help keep our cellular powerhouses running smoothly, like giving them a little extra fuel.

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Alex Mathew

@alxmthew

1 year

@tksworldhq studying gene editing through tks's 🧬models! super excited to see the cross section of gene editing and ai!

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Alex Mathew

@alxmthew

15 days

🧠 Did you know? Emotional dysregulation is linked to how the brain’s reward system functions. When dopamine pathways get off track, even negative behaviors can feel rewarding. This makes breaking unhealthy habits incredibly difficult. Here are some signs:

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Alex Mathew

@alxmthew

1 year

@tksworldhq i loved alishba's article. i think a lot of teens at my school take for granted the privelage we have to be where we are. embracing these stoic believes have been really helpful when dealing with cracks in my energy. i have learned to manage my energy well!

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Alex Mathew

@alxmthew

14 days

6/7 🆘 I recently watched the 4hr video on CEOs social media testifying in a U.S. Senate hearing We can't rely on Big Tech or the government to fix this. It's on us. Digital literacy isn't a luxury, it's survival. Parents, educators, teens – we need to talk. For real.

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Alex Mathew

@alxmthew

4 months

@zoink a lot but recently, wanting figma to have a hoodie designer!

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Alex Mathew

@alxmthew

1 year

@tksworldhq an explanation of crispr-cas9: cas9: a protein that acts as scissors that can cut dna. crispr: a sticky note that tells cas9 where to cut. we use crispr-cas9 to edit genes by sticking cas9 to a place in the dna with crispr. then, we either remove or replace the dna part!

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Alex Mathew

@alxmthew

6 months

@laurenap_ @_TheResidency @nick_linck @edchucation @meichenster IM SO PROUD LAUREN <3

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Alex Mathew

@alxmthew

9 months

@tksworldhq imagine having a vr therapy session with a professional in a different country or a vr tech meetup with people all over the world... that's what the metaverse can make a reality

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Alex Mathew

@alxmthew

11 months

@tksworldhq imagine playing mario kart with nothing but your brain. in the future i'll be controlling my motorcycle with baby luigi and blue turtle shells! excited to see the future with bcis x gaming!

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Alex Mathew

@alxmthew

15 days

5/ The overlap between these behaviors suggests a shared neural pathway, reinforcing the idea that eating disorders and self-harm are neurobiologically connected. It’s not just about willpower or appearance—it's about the brain’s wiring.

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Alex Mathew

@alxmthew

3 months

@KrishivThakuria @_buildspace @_nightsweekends so cool! very very similar to what i’m working with too except mines more targeted towards mental health. very excited to see what’s next!

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Alex Mathew

@alxmthew

9 months

proof of work (pow) is like traditional mining—computers solving complex puzzles to validate transactions on a blockchain. proof of stake (pos) is where validators are chosen to create new blocks based on the amount of crypto they hold and are willing to "stake" as collateral.

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Alex Mathew

@alxmthew

2 months

kindness is a language that the deaf can hear and the blind can see

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Alex Mathew

@alxmthew

1 year

@tksworldhq i find that teens care too much about other people's opinions. social media does fuel this but we shouldn't blame it on our screens. this culture is promoted everywhere. it's so hard to actually be yourself (like stoicism says) bc of this. where can we actually be ourselves?

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Alex Mathew

@alxmthew

15 days

#mentalhealth #eatingdisorders #teenmentalhealth #neuroscience

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Alex Mathew

@alxmthew

1 year

@tksworldhq @davidrliu what recent innovations in genome editing methods do you believe have the greatest potential to revolutionize precision genetic engineering? and how do you envision advancing base editing techniques to address specific genetic diseases with high precision?

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Alex Mathew

@alxmthew

2 months

perspective is the alchemy that transmutes the mundane into the extraordinary, imbuing life with a kaleidoscope of meaning

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Alex Mathew

@alxmthew

6 months

@KrishivThakuria looks so fun krishiv!!!

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Alex Mathew

@alxmthew

11 days

Surprising brain connection in anorexia: stronger links between ventral striatum & hypothalamus may reinforce restrictive eating. This neural pathway could explain why breaking the cycle is so tough

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Alex Mathew

@alxmthew

1 year

@tksworldhq the thought of curing cancer with gene editing honestly blows my mind. i was thinking if there was a way to automate gene editing using ai to cure cancer (check, and execute method). :)

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Alex Mathew

@alxmthew

3 months

@BafnaVibhuti @CollisionHQ @tksworldhq it’s simply the best

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Alex Mathew

@alxmthew

15 days

7/ An estimated 108M teens globally are struggling with eating disorders. That’s staggering. This issue is far too big to ignore, and I hope this thread has shed some light on just how serious and widespread it is. It’s time for action.

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Alex Mathew

@alxmthew

1 year

@tksworldhq instead of waking up every day at 4:30am, for the past week i cut out netflix. reflecting on it, it was amazing. at many times i wanted to go back to watching shows but it gave me so much more time to do the things i love! next week: no non-educational youtube, 11pm 💤, 6am wake.

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Alex Mathew

@alxmthew

12 days

3️⃣ Norepinephrine: part of the stress response, increasing alertness and focus. Low norepinephrine levels can contribute to depression, while high levels are linked to anxiety.

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Alex Mathew

@alxmthew

12 days

@ivoinetech @SunirKM this looks like a fire call. would love to break down a paulg essay with yall someday!!!

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Alex Mathew

@alxmthew

14 days

2/7 💉 The Dopamine Dealer in Your Pocket Every 'like' is a hit. Every comment, a high. These change the way our reward system works. Social media's addiction is the perfect drug – and teens are the lab rats. But wait, it gets worse...

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Alex Mathew

@alxmthew

15 days

6/ The brain's reward system plays a massive role in these conditions. Understanding this could revolutionize how we treat and prevent eating disorders, self-harm, and even addiction. This is a serious problem, especially for teens.

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Alex Mathew

@alxmthew

15 days

2/ Studies show 72% of eating disorder patients also engage in non-suicidal self-injury (NSSI). What’s the link? It’s all in the brain’s reward circuits, which become dysregulated, making harmful behaviors feel “rewarding.”

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Alex Mathew

@alxmthew

9 months

@tksworldhq why it's so hard to explain the metaverse: it's not just VR games, it is composed of a synchronous, persistent network with an unlimited amount of individualistic users. that was a lot of words... basically, it's an online world supporting interconnectivity between a lot of ppl

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Alex Mathew

@alxmthew

3 months

@stavanpatel

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Alex Mathew

@alxmthew

17 days

adults, teens, and kids alike, use transitional objects (like a stuffed toy or jewelry) for comfort & security these can help reduce stress, ease anxiety, and help prevent deeper mental health issues. imagine having one you could talk to at anytime! 👀

Serenity Plushies

AI-powered stuffed animals for pre-teens and teens.

plushies.so

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Alex Mathew

@alxmthew

9 months

with hashing you can turn your data (from the blockchain) into a code that's unique and secure. it's like a secret language for computers, making sure your info stays safe and sound. 👍🔐

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Alex Mathew

@alxmthew

7 months

@_buildspace ALWAYS FIRE CONTENT!!! you somehow solve the problems i have stuck in the back of my head <3. feedback: if i didn't know what buildspace was i probably wouldn't watch the long lectures so maybe having short videos covering all of the points, not just sections of the video :)

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Alex Mathew

@alxmthew

8 months

@nick_linck exciting! looking forward to our chat :)

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Alex Mathew

@alxmthew

7 months

@_broskitweets THIS IS EPIC!!! wishing u best of luck

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Alex Mathew

@alxmthew

11 months

@tksworldhq what are stem cells? stem cells have the unique ability to transform into different cell types. there are two different types of stem cells. embryonic stem cells (escs) are pluripotent and found in embryos. adult or somatic stem cells, located in various tissues, are multipotent.

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Alex Mathew

@alxmthew

3 months

@_aysyed @siliconvalleyf @_TheResidency 🫡

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Alex Mathew

@alxmthew

12 days

1️⃣ Serotonin: Known as the "happy chemical," serotonin helps regulate mood, sleep, appetite, and memory. Low levels are linked to depression and anxiety. SSRIs, a common antidepressant, work by increasing serotonin levels.

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Alex Mathew

@alxmthew

9 months

@tksworldhq the difference btwn AR + VR is easy to understand. AR adds immersive components to the real world. Pokemon GO + Amazon both have AR features allowing you to see a Pokemon or furniture in your own house! VR is a fully immersed virtual experience, no elements from our own world!

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Alex Mathew

@alxmthew

1 year

@tksworldhq amor fati - i want it this way, it won't stop me memento mori - life is short, i'm going to die what do you control? let's say your in a fight with someone. repeat these phrases, don't let it get to you.

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Alex Mathew

@alxmthew

12 days

2️⃣ The INFAMOUS Dopamine: involved in reward, motivation, and pleasure. It plays a role in addiction, ADHD, and schizophrenia. Medications for these conditions often target the dopamine system to restore balance.

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