Myrsini Kaforou @_myrsini_ Twitter profile

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Myrsini Kaforou

@_myrsini_

10 months

Seriously now @aegeanairlines @HeathrowAirport ?! How on earth did this happen?! 😡

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Myrsini Kaforou

@_myrsini_

4 years

Very happy to receive the President's Award for Outstanding Early Career Researcher @imperialcollege in this year's virtual ceremony🍾We will hopefully celebrate soon in person with the brilliant team at the Section of Paediatric Infectious Disease @ImperialInfect

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Myrsini Kaforou

@_myrsini_

4 years

Our paper on the clinical characteristics of children with SARS-CoV-2 associated Pediatric Inflammatory Multisystem Syndrome #PIMSTS and the comparison with KD, KD shock & TSS suggests this disorder differs from other pediatric inflammatory conditions

Clinical Characteristics of Children With SARS-CoV-2–Associated Pediatric Inflammatory Multisystem...

This case series describes the clinical and laboratory characteristics of children hospitalized in England from March to May 2020 who met criteria for pediatric inflammatory multisystem syndrome...

jamanetwork.com

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Myrsini Kaforou

@_myrsini_

5 years

Such an honour. Massive thanks to the @MedResFdn for the first-place #EmergingLeaders2019 prize. A wonderful evening at the @ExploreWellcome celebrating science and plotting against #AMR . 🥂 And a recognition for all the work we do @ImperialInfect on host based diagnostics.

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Myrsini Kaforou

@_myrsini_

1 year

1/13 Excited to share our study describing a 161 gene signature able to simultaneously classify 18 paediatric infectious & inflammatory diseases using multi-class supervised #Machinelearning . Out in @MedCellPress after a few years in the making 📰

Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature

A multi-class supervised machine-learning approach applied to whole-blood transcriptomics can classify 18 categories of pediatric infectious and inflammatory diseases, reflecting individual causative...

www.cell.com

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Myrsini Kaforou

@_myrsini_

3 years

📢Out today in @LancetMicrobe our article presenting a 3-gene signature in blood able to distinguish viral infections and #COVID19 from other causes of illness in emergency infectious disease presentations in adults🦠 (1/7) Thread summarising key points🧵⤵️

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Myrsini Kaforou

@_myrsini_

4 years

Today @JAMAPediatrics read about our efforts to move the host blood RNA 2-gene signature for distinguishing bacterial from viral infection a step closer to clinical application with rapid and cost-effective detection. (1/5)

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Myrsini Kaforou

@_myrsini_

10 months

Huge congratulations to Professor @acunningID on his brilliant inaugural lecture! 👏 His research journey, infectious enthousiasm and work ethic is an inspiration to us all! 🍻

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Myrsini Kaforou

@_myrsini_

1 year

📢Our latest paper describing a blood-based host protein signature for distinguishing between bacterial and viral infections in children with fever from the @PERFORM_2020 @EU_Commission study is out in Lancet Digital Health @LancetDigitalH . A thread🧵1/12

A multi-platform approach to identify a blood-based host protein signature for distinguishing...

This study has led to the identification of a protein signature that could be ultimately developed into a blood-based point-of-care diagnostic test for rapidly diagnosing bacterial and viral infect...

www.thelancet.com

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Myrsini Kaforou

@_myrsini_

5 years

Thrilled that our new @EU_H2020 project @DIAMONDS_2020 is kicking off this month! Gene signatures measured in blood will be used to rapidly identify a spectrum of diseases. The first pilot trial in hospitals in 2023.🤞 #ResearchImpactEU

Imperial team win €22.5m EU funding to develop rapid test for serious illnesses | Imperial News |...

GENE SIGNATURE TEST - A rapid test to diagnose severe illnesses, using personalised gene signatures, is being developed by scientists at Imperial College London.

www.imperial.ac.uk

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Myrsini Kaforou

@_myrsini_

5 years

Nice illustration from @DebbyBogaert to highlight why the ratio of #covid19 deaths/detected cases is not a comparable metric across countries. Number of deaths/population more comparable assuming similar healthcare practices/accessibility/quality.

Prof. Debby Bogaert 💙

@DebbyBogaert

5 years

I see a lot of questions asking why Germany has a relative low % of #Covid deaths. To illustrate, I used the Iceberg analogy showing the effects of testing on detection rate and thereby reported death rate. The more of the iceberg visible, the lower the reported death rate.

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Myrsini Kaforou

@_myrsini_

2 years

Huge congratulations to the amazing Dr @hrjackson_ for passing her viva today with no corrections! 🥳 Many thanks to Prof Becca Asquith @ImperialInfect and Dr @gpollara for examining - @jetpackjeth and Mike Levin for cosupervising! Grateful to @wellcometrust for funding. 🙏

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Myrsini Kaforou

@_myrsini_

5 years

Thrilled! This is a fantastic recognition of all the efforts and successes of everyone in the team! 🎉

Imperial Medicine

@ImperialMed

5 years

👏 Congratulations to all 40 members of the Paediatric Infectious Diseases Team led by Prof Michael Levin for winning Outstanding Research Team!

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Myrsini Kaforou

@_myrsini_

4 years

In 2020 @NatureComms publishes a paper suggesting that women should be mentored by men in order to succeed in academia.🤬"Our gender-related findings suggest ... female–female mentorships ... could hinder the careers of women who remain in academia..." I am furious.

Heather Jackson

@hrjackson_

4 years

This thread👇🏼 I for one feel honoured to have a female mentor/supervisor @_myrsini_ 🌟

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Myrsini Kaforou

@_myrsini_

4 years

Congratulations @ajpollard1 @OxfordVacGroup and the rest of the Oxford Team! What an achievement.

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Myrsini Kaforou

@_myrsini_

4 years

1/2: Seems to me that Greece could be faced with a problem. The plot shows the number of air journeys from London to other countries in October 2020. *Greece is 3rd* Coloured bars indicate countries that report the presence of the new variant B.1.1.7/VUI-202012/01 (26/12/2020)

Moritz Kraemer

@MOUGK

4 years

We have added more information to the global B.1.1.7 lineage tracker including travel data from the UK to countries around the world in October 2020 (latest data). See more details here . Will update as new data comes in.

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Myrsini Kaforou

@_myrsini_

6 years

Our paper on the 4 gene #diagnostic blood based signature for #tuberculosis is now @biorxivpreprint : For the first time digitalPCR results show how many copies of the RNA molecules patients have in their blood, which is crucial for test development. #endTB

Identification of reduced host transcriptomic signatures for tuberculosis and digital PCR-based...

Recently, host whole blood gene expression signatures have been identified for diagnosis of tuberculosis (TB). Absolute quantification of the concentrations of signature transcripts in blood have not...

www.biorxiv.org

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Myrsini Kaforou

@_myrsini_

3 years

Our paper on using host transcriptomics and proteomics to shed light on disease pathogenesis in #KawasakiDisease is now out⬇️ Big congrats to @hrjackson_ for her first fist-author publication! 🎉

Heather Jackson

@hrjackson_

3 years

The work I had the pleasure of presenting yesterday at @ESPIDsociety has now been published online @IJMS_MDPI ! A thread 🧵to summarise our findings... (1/5)

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Myrsini Kaforou

@_myrsini_

4 years

Fascinating findings at an incredible speed. Massive congrats🍾 to the @ImperialInfect team: @SanchoShimizu @HodeibStephanie @IraSabli *15% of severe COVID-19 have either type I IFN inborn errors or type I IFN auto-antibodies *94% of the patients with auto-antibodies were male!

Casanova Lab

@casanova_lab

4 years

We have been silent for a while because our lab and the CHGE were entirely focused on finishing 'twin papers' in @ScienceMagazine about inborn errors of type I IFN or auto-antibodies to type I IFN in nearly 15% of patients with life-threatening #COVID19 😀

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Myrsini Kaforou

@_myrsini_

4 years

Just landed in Athens to this lovely piece from @GoodNewsGR - thank you! ☀️

GoodNews

@GoodNewsGR

4 years

Το βραβείο "Outstanding Early Career Researcher" έλαβε η Δρ Μυρσίνη Καφώρου ( @_myrsini_ ), ερευνήτρια στο Τμήμα Λοιμωδών Νοσημάτων του @imperialcollege .

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Myrsini Kaforou

@_myrsini_

6 years

Our paper on diagnosing #KawasakiDisease in children using a minimal blood gene expression signature is out today @JAMAPediatrics . The potential for the first ever diagnostic test is real. #transcriptomics #RNAdiagnostics @DoM_Imperial @UCSDMedSchool

Diagnosis of Kawasaki Disease Using a Minimal Whole-Blood Gene Expression Signature

This case-control study identifies a whole-blood gene expression signature that distinguishes children with Kawasaki disease in the first week of illness from other febrile conditions.

jamanetwork.com

Imperial Department of Infectious Disease

@ImperialInfect

6 years

Out today in @JAMAPediatrics : @DoM_Imperial researchers have identified a unique genetic pattern in children with #Kawasaki Disease, paving the way for the first ever diagnostic test:

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Myrsini Kaforou

@_myrsini_

3 years

The @BATStudy publishes its first results on comparing outcomes for different treatments in cases of #MISC - Multisystem Inflammatory Syndrome in Children @NEJM today. An incredible international effort led by @ImperialInfect

Best Available Treatment Study

@BATStudy

3 years

Delighted that our analysis of the first 614 patients enrolled to the study has been published in @NEJM !

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Myrsini Kaforou

@_myrsini_

4 years

Our preprint is out! Longitudinal gene expression analysis in stimulated blood of IGRA+ individuals who were given #tuberculosis preventive therapy highlighted two distinct IGRA+ subgroups. 2/3 of the IGRA+s clustered with IGRA-unexposed controls, while 1/3 clustered away.

bioRxiv

@biorxivpreprint

4 years

Host transcriptional response to TB preventive therapy differentiates two sub-groups of IGRA-positive individuals #bioRxiv

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Myrsini Kaforou

@_myrsini_

4 years

📣📣 The Best Available Treatment Study is now live If you have cared/caring for *children with inflammatory syndromes temporally associated with #SARSCoV2 *, #PIMS_TS #MIC_S #Kawasaki_like , please join and share. #COVID19

Aubrey Cunnington

@acunningID

4 years

Calling all pediatricians! A new global study to identify promising treatments for inflammatory syndromes associated with #SARSCoV2 in children. PIMS-TS/ MIS / MIS-C. Please contribute data here: @RCPCHtweets @ESPIDsociety @PICSociety @EAPaediatrics

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Myrsini Kaforou

@_myrsini_

6 years

3D structure of flagella made with lego bricks - #ScienceSunday @imperialcollege #ImpFest #superbugzone @CMBI_Imperial @cmbi_cpa

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Myrsini Kaforou

@_myrsini_

6 years

On my way to @lindaunobel meeting #LiNo18 dedicated to Medicine and Physiology! Happy coincidence: today is the International Women In Engineering Day. 💪 #InterdisciplinaryResearch #CreateYourOwnPath #INWED18 #RaisingTheBar #WomeninSTEM

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Myrsini Kaforou

@_myrsini_

4 years

Congratulations team! Amazing achievement! 👍

Pantelis Georgiou

@pgeorgiou_ic

4 years

We’ve done it! The first handheld molecular diagnostic for rapid detection of SARS-CoV-2! Validation results - average detection time <13 mins, 90.5% sensitivity & 100% specificity from clinical samples. Huge thanks to my amazing team and collaborators!

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Myrsini Kaforou

@_myrsini_

6 years

#LiNo18 What a week! An experience I will cherish. Meeting the pioneers of Medicine & Biology #NobelLaureates , mingling with brilliant young scientists from around the globe & listening to lively debates in a beautiful place. Thanks to @royalsociety @DoM_Imperial @Boehringer .

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Myrsini Kaforou

@_myrsini_

5 years

My first 10K run done - so happy 🎉 And for a good cause @royalmarsden #kxuladygardenrun2019

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Myrsini Kaforou

@_myrsini_

6 years

Thrilled to hear that we have received the @RosetreesT Trust Interdisciplinary Award! A step closer to the development of a point-of-care diagnostic test for bacterial infection via a fantastic collaboration with @pgeorgiou_ic 's lab that was initiated within @ARC_at_Imperial

Pantelis Georgiou

@pgeorgiou_ic

6 years

Honoured we have received the 2018 ⁦Rosetrees Trust Interdisciplinary Award to develop a microchip based diagnostic for rapid detection of infection in children w/ M. Levin J. Herberg ⁦ @_myrsini_ ⁩ & J. Rodriguez @RosetreesT ⁩ @imperialeee ⁩ ⁦

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Myrsini Kaforou

@_myrsini_

3 years

New preprint unravels blood gene expression differences in adults with varying #COVID19 severity using #RNAsequencing @ImperialInfect Always fantastic to work with our friends at @GENVIP_RESEARCH - @fedemartinon @AntonioSalasEl1 @CarballaGomez

Characterisation of the blood RNA host response underpinning severity in COVID-19 patients

Infection with SARS-CoV-2 has highly variable clinical manifestations, ranging from asymptomatic infection through to life-threatening disease. Host whole blood transcriptomics can offer unique...

www.medrxiv.org

Heather Jackson

@hrjackson_

3 years

In our new preprint we used #RNAseq to explore the whole blood transcriptomes of individuals with varying severity of #COVID19 , using differential expression analysis and pathway analysis graphical abstract and 🧵to summarise...

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Myrsini Kaforou

@_myrsini_

5 years

And it's a wrap for this year's @imperialcollege science festival ☀️ Hope our visitors enjoyed our diagnostic clinic, as much as we did! #ExRdFest #MalariaZone Thanks to @acunningID for driving this and keeping the enthusiasm high the whole time! 🙌 @PERFORM_2020 @DoM_Imperial

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Myrsini Kaforou

@_myrsini_

5 years

Well done to @neil_ferguson @azraghani and the rest of the team at @imperialcollege for bringing science, evidence and sanity to the table! At last: new data, new policy: why UK's coronavirus strategy changed #listentotheexperts

New data, new policy: why UK's coronavirus strategy changed

New quarantine and social distancing ‘suppression’ measures are based on modelling by Imperial College to move beyond ‘mitigation’

www.theguardian.com

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Myrsini Kaforou

@_myrsini_

4 years

The Centre for Integrative Systems Biology and Bioinformatics (CISBIO) @imperialcollege is organising an open day 15th/16th Feb : *Modelling Biological Systems: An International Perspective* Save the date and register for more info⬇️ Top speakers 🗺️

CISBIO OPEN DAY - IMPERIAL COLLEGE LONDON

Centre for Integrative Systems Biology and Bioinformatics Modelling Biological Systems: An International Perspective”

www.eventbrite.co.uk

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Myrsini Kaforou

@_myrsini_

5 years

Excellent analogy by @fedemartinon on what @DIAMONDS_2020 is all about! 🎹 I guess I am doing the Shazam part 👩‍💻 PS: Some ideas for public engagement spring to mind 🎵

Federico Martinón-Torres

@fedemartinon

5 years

DIAMONDS project: If the genes are the keys in a piano, then transcriptomics, as the functional expression of those genes, is the melody. Depending on how you play the keys, that is how your genes are activated or inhibited, the melody will be different. @DIAMONDS_2020

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Myrsini Kaforou

@_myrsini_

5 years

Infectious #ImperialLates is buzzing! And the usual suspects are showcasing their amazing way of monitoring and diagnosing infections: @MiguelCach91 @kenny_IC @NickMoserIC and busy @PennisiIvana well done! @ImperialInfect @pgeorgiou_ic @jesusrodman @jetpackjeth @acunningID

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Myrsini Kaforou

@_myrsini_

4 years

Join us next week to find out about the achievements of @PERFORM_2020 and the vision and aims of @DIAMONDS_2020 - Although we will miss our f2f meeting in Santiago de Compostela, we are excited that we can share our work with everyone. 📢

PERFORM

@PERFORM_2020

4 years

Free webinar: Novel approaches to distinguishing bacterial from viral infections: lessons learnt from @PERFORM_2020 and next steps in @DIAMONDS_2020 . 18 November 10AM (CET). To register and for speaker programme:

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Myrsini Kaforou

@_myrsini_

4 years

thank you John! Would also like to celebrate all the brilliant women in the PID bioinformatics team! From all walks of life indeed! @ACheyne33 @OrtensiaVito @hrjackson_ @DrCBroderick @ClaireDunican @AndradiClare @Rebecca91120426 @clare__wilson ⌨️👏🎉 #womenwhocode #WomenInScience

Professor John Tregoning

@DrTregoning

4 years

And of course there's #Bioinformatics @ImperialInfect we take scientists from all walks of life - even chemical engineers! @_myrsini_ is developing host RNA signatures to distinguish viral from bacterial infection. #WomenInScienceDay2021

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Myrsini Kaforou

@_myrsini_

4 years

Exactly the stereotype incredible women are breaking! @BeateKampmann @SanchoShimizu @lizWWyld @drbethholder @CarrolEnitan @mariekeemonts @MTsolia @Grampospath @MartaIGarrido @AthinaofAthens @mnkustef @IRINIELEFTHERI2 @bioin4gal @irenepapatheodo @DrCCostelloe @WOMENinSTEM_IC

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Myrsini Kaforou

@_myrsini_

5 years

If you are looking for a Postdoc, come work with us on a project that aims to transform the way we diagnose infections! Based at @ImperialInfect & @imperialeee working with @pgeorgiou_ic @jetpackjeth @jesusrodman & myself, following the award of the @RosetreesT Prize. RT please.

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Myrsini Kaforou

@_myrsini_

3 years

#JobOppurtunity @ImperialInfect Together with @grahamscooke we are looking for a Research Fellow in #Bioinformatics & #PrecisionMedicine to join us in the analysis of multi-omics from clinical studies of hepatitis C, COVID-19 and other infections #RT pls

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Myrsini Kaforou

@_myrsini_

5 years

RNA sequencing: the teenage years - an excellent review @NatureRevGenet #RNAseq #transcriptomics

Eric Topol

@EricTopol

5 years

The definitive review—and look to the future—of RNA sequencing @NatureRevGenet (all of 26 pages!) by @coregenomics Rory Stark, Marta Grzelak @PacBio @nanopore @illumina

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Myrsini Kaforou

@_myrsini_

4 years

@DIAMONDS_2020 @EU_H2020 website is now live: Read about our efforts to revolutionise the diagnosis of infectious and inflammatory diseases using blood #RNA markers and the contribution of each #EU partner. #transcriptomics #personalisedmedicine 🦠🧬💻💊

DIAMONDS: Personalised Molecular Testing For Serious Illness

www.diamonds2020.eu

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Myrsini Kaforou

@_myrsini_

2 years

Check out our new manuscript in @SciReports comparing whole blood transcriptomics from an in vitro mycobacterial growth assay and patients with #tuberculosis disease - 🧵🩸🫁 1/9

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Myrsini Kaforou

@_myrsini_

4 years

📢A day of TB host transcriptomics milestone papers! A bit of reading to do. Congratulations to the teams involved!

The Lancet Infectious Diseases

@TheLancetInfDis

4 years

2 research articles + comments on transcriptomic signatures for #tuberculosis diagnosis 1) Biomarker-guided tuberculosis preventive therapy (CORTIS): a randomised controlled trial

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Myrsini Kaforou

@_myrsini_

5 years

So many correct diagnoses made by the little doctors at the #malariajungle clinic today. Absolutely fantastic. Join us again tomorrow at the Exhibition Road Festival. #ExRdFest @DoM_Imperial @imperialcollege 🔬

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Myrsini Kaforou

@_myrsini_

7 years

Thrilled and honoured to hear that I was selected to participate in the Lindau Nobel Meeting 2018! @lindaunobel Thanks @royalsociety and @DoM_Imperial for the nomination! #LiNo18 #scientificinspiration

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Myrsini Kaforou

@_myrsini_

4 years

WHY use excel at the first place for this? 🤦‍♀️ interesting that the excel gene names errors get in the spotlight too.

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Myrsini Kaforou

@_myrsini_

5 years

What an incredible honour! Thank you super talented @ACheyne33 for picking me and the #bioinformatics aspect of your PhD for your amazing painting "The Bioinformatics Battlefield of Tuberculosis"! #peoplesvote #researchart #proudsupervisor @DoM_Imperial @ImperialSci 😊😮😭

Ashleigh Cheyne

@ACheyne33

5 years

The research as art exhibition is now OPEN!!! 😱😱😱 a MASSIVE thank you to @_myrsini_ for being my model for this piece! #tuberculosis #art #researchasart @ImperialSci @CMBI_Imperial @CMBI_Imperial @gLarrouyM_Lab @imperialcollege

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Myrsini Kaforou

@_myrsini_

6 years

2nd annual meeting at the University of Cape Town @UCT_news for our @NIH funded paediatric #tuberculosis #biomarkers consortium. A step closer to #EndTB . #TBbiomarkers #diagnostics @DoM_Imperial @mrcunitgambia @imperialeee @UniLeidenNews @StellenboschUni @mcgillu

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Myrsini Kaforou

@_myrsini_

3 years

Job done? Or is it just an exciting new beginning? What an incredible meeting today! Shame we can't celebrate with a f2f🍹 - @PERFORM_2020 @HorizonEU @Imperial_RPM @ImperialInfect @jetpackjeth @acunningID @fedemartinon @CarrolEnitan @MTsolia @mariekeemonts @ejlim8 @ajpollard1

Aubrey Cunnington

@acunningID

3 years

So did @PERFORM_2020 succeed in making a test to distinguish bacterial from viral infection in children? #PERFORMingLive Karen Brengel unveils the @biomerieux @BioFireDX PERFORM RNA pouch for #FilmArray platform. 1 hour sample to result AUC of 0.94. Job done? See @DIAMONDS_2020

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Myrsini Kaforou

@_myrsini_

5 years

#TIPICOX I made it to the legendary @TIPICO_SANTIAGO meeting, that celebrates its 10th anniversary this year! Impressive attendance and fantastic talks. Thanks to @fedemartinon and the @GENVIP_RESEARCH team for the out-of-this-world hospitality.

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Myrsini Kaforou

@_myrsini_

4 years

Made possible by the valuable patient databanks @EUCLIDS_FP7 @PERFORM_2020 @DIAMONDS_2020 Future comparative analyses of #PIMSTS patient molecular data (RNAseq 🤞) against databanks of other infectious & inflammatory conditions will hopefully further our understanding. #COVID19

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Myrsini Kaforou

@_myrsini_

5 years

Great work from @ajpollard1 and team on the 1st GWAS for vaccine response in children which identified common variants associated with persistence of immunity after vaccination for MenC, Hib and TT #VaccinesWork #VaccinesSaveLives

Eric Topol

@EricTopol

5 years

The 1st GWAS for response of children to vaccines @CellReports #openaccess individualized response to Hib, TT, MenC vaccines for persistence of immunity @CellPressNews @UniofOxford and collaborators

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Myrsini Kaforou

@_myrsini_

5 years

#eurobarometer data show that 46% of EU citizens on average believe that antibiotics kill viruses. 🤯 The percentage for Greece, where antibiotics are available over the counter, is 75%! Definitely more to be done! #AMR #knowledgeispower @PERFORM_2020 #ESPID2019 @eody_gr

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Myrsini Kaforou

@_myrsini_

2 years

Huge congratulations @PennisiIvana 🎉 - what an amazing journey! Many thanks to @JamesSeddon10 and @maluquerlab for examining Ivana's thesis.

Pantelis Georgiou

@pgeorgiou_ic

2 years

Huge congratulations to @PennisiIvana for defending her PhD on ‘New molecular methods for point-of-care infectious disease diagnosis’ Fantastic collaborative work co-supervised by Mike Levin, @_myrsini_ @jesusrodman . Many thanks to James Seddon & Carlos Maluquer for examining!

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Myrsini Kaforou

@_myrsini_

4 years

Study by @BRFAA_IIBEAA (article in Greek) suggesting that a mink associated variant strain was detected in at least 120 cases of COVID19 in NW Greece, an area that saw a very high number of transmissions and deaths in Nov-Dec. @ArisKatzourakis

ΙΙΒΕΑΑ: Μεταλλαγμένα στελέχη από μινκ εντοπίστηκαν σε 120 κατοίκους της Δυτικής Μακεδονίας

Μεταλλάξεις του κορονοϊού που πέρασαν από τα μινκ στους ανθρώπους το ΙΙΒΕΑΑ διερευνά αν ευθύνονται για τη μεγαλύτερη διασπορά στη Βόρεια Ελλάδα.

www.iatropedia.gr

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Myrsini Kaforou

@_myrsini_

4 years

Read about a really important arm of the @PERFORM_2020 project led by @ejlim8 and @mariekeemonts on how actively involving young persons in the study shaped clinical research processes @EU_H2020 ⬇️

PERFORM

@PERFORM_2020

4 years

Why involving young people in research is important and how it changed the PERFORM study. News article looking at PERFORM researchers and their work with The Young Person’s Advisory Group North England. @YPAGne @ejlim8 #YPVoice @mariekeemonts

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Myrsini Kaforou

@_myrsini_

5 years

Thank you @ESPID_Society for the invitation. An absolute pleasure being here and showcasing our latest research endeavours in translational medicine @PERFORM_2020 @EUCLIDS_FP7

ESPIDSociety

@ESPIDsociety

5 years

Talk on “Diagnostic and prognostic transcriptomics biomarkers in infection” by @_myrsini_ at #ESPID2019 . Joint symposium with @ESCMID .

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Myrsini Kaforou

@_myrsini_

4 years

Nice coverage of the back story. Highlights once more the need for Findable, Accessible, Interoperable and Reusable (FAIR) data in medical science, and white-box accountable and reproducible tools. #FAIRdata

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Myrsini Kaforou

@_myrsini_

4 years

New insights from @D_Busse92 @DrTregoning and team on the role of IFI44L and IFI44 -two of my favourite genes- in controlling #RSV , using overexpression systems, CRISPR-Cas9-mediated knockout and a knockout mouse model. @ASMicrobiology #Jvirology @ImperialInfect

Professor John Tregoning

@DrTregoning

4 years

Our paper on IFI44 as a restriction factor for RSV is out in @JVirology with @D_Busse92 @_myrsini_ @jetpackjeth Interferon-induced Protein-44 and Interferon-induced Protein 44-like restrict replication of Respiratory Syncytial Virus

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Myrsini Kaforou

@_myrsini_

5 years

This weekend at the Exhibition Road Festival #ExRdFest #malariazone you can help us diagnose infectious diseases using #RNAbiomarkers 🕵️👩‍💻 We'll be showcasing our latest research using multi-class diagnosis & pH-change based detection. I certainly cannot wait. 🎉 @PERFORM_2020

Imperial College London

@imperialcollege

5 years

"The Great Exhibition Road Festival will feature more than 150 events from museums, galleries, concert halls and research centres, inspired by the Great Exhibition of 1851" ( @EveningStandard )

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Myrsini Kaforou

@_myrsini_

4 years

Massive congratulations to Dr @enDespuig for a brilliant thesis defence this morning! Thanks for inviting me to be part of this fantastic project! Congrats @tbexperimental 🍻 A beer in Barcelona will remain on the do to list for the post-vaccine life! 🎉

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Myrsini Kaforou

@_myrsini_

4 years

This is @PennisiIvana 's first first-author paper🎉& the output of a fantastic collaboration with @pgeorgiou_ic @jesusrodman @ImperialCBIT @imperialeee that started @ARC_at_Imperial years ago & is going strong funded by @RosetreesT with @jetpackjeth @ImperialInfect (4/5)

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Myrsini Kaforou

@_myrsini_

6 years

The Chair Stefan Kauffman @maxplanckpress opens the annual meeting describing the succession of successful EU funded TB grants. #TBVAC2020 #lesdiablerets2019 @EU_H2020 - More than 10 promising TB vaccine candidates in different phases of formal testing! #vaccineswork .

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Myrsini Kaforou

@_myrsini_

3 years

#ESPID2021 #ESPIDanywhere now Session on📢Digitalisation and machine learning in clinical microbiology @ESPIDsociety - so cool to see ML featuring on a parallel session. 🔝

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Myrsini Kaforou

@_myrsini_

4 years

Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing which combines simplified extraction of RNA with isothermal amplification and CRISPR mediated detection. 402 samples tested: sensitivity 93.1%, specificity 98.5%.

Detection of SARS-CoV-2 with SHERLOCK One-Pot Testing | NEJM

A new method for the detection of SARS-CoV-2 combines simplified extraction of RNA with isothermal amplification and CRISPR (clustered regularly interspaced short palindromic repeats)–mediated dete...

www.nejm.org

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Myrsini Kaforou

@_myrsini_

4 years

Interested in a PhD on host based diagnostics for infectious diseases based at @imperialeee and @ImperialInfect , working closely with @mologic and funded by the @The_MRC ? Apply here to join the team ⬇️⬇️ #diagnostics #PhDposition @FindAPhD #findPhD

Nicolas Moser

@NickMoserIC

4 years

Interested in joining us for a PhD? Last chance to apply to the Enterprise DTP iCASE Doctoral Training Programme to revolutionise antibody testing on a microchip! #Lacewing @pgeorgiou_ic @jesusrodman @_myrsini_ @acunningID @imperialeee @ImperialInfect

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Myrsini Kaforou

@_myrsini_

4 years

Watch @hrjackson_ 's fantastic video explaining her PhD project in a really fun way! 👏🎉 @PERFORM_2020 @DIAMONDS_2020 #omicsresearch

Heather Jackson

@hrjackson_

4 years

My attempt at explaining my PhD research in a (slightly longer than) 2 minute video!

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Myrsini Kaforou

@_myrsini_

5 years

An exciting #PhD project in #tuberculosis immunology @mrcunitgambia supervised by @Sutherland_TB ! Can it get any better? ☀️

Prof Jayne Sutherland

@Sutherland_TB

5 years

Come and join us in The Gambia for an exciting PhD project on TB. Project outline here: and information on how to apply here:

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Myrsini Kaforou

@_myrsini_

8 years

Our paper on a 2-gene test for detection of bacterial infections is out: @JAMA_current @DoM_Imperial @PERFORM_2020

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Myrsini Kaforou

@_myrsini_

5 years

A great day to spend @kewgardens at the @wellcometrust @imperialcollege bioinformatics and systems biology PhD student away day. The keynote on studying cancer tumour evolution and dissecting their complexity from Chris Barnes @cssb_lab was very inspiring.

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Myrsini Kaforou

@_myrsini_

5 years

Congratulations @AthinaofAthens @acunningID and team! Amazing!👏👏

Athina Georgiadou

@AthinaofAthens

5 years

Our paper using #computationalmodels and #transcriptomics in #malaria reveals novel host protective mechanisms against #Plasmodium falciparum! Check it out in @NatureMicrobiol ()!! Amazing team work and collaborators: @acunningID , Hyun Jae Lee @mthbretscher

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Myrsini Kaforou

@_myrsini_

6 years

#LiNo18 Prof Louis J. Ignarro #NobelPrize for demonstrating the signaling properties of nitric oxide "The road to Stockholm is via approaching big problems with simple logic". Btw I am really enjoying the bold political statements & open-mindedness in this @lindaunobel meeting.

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Myrsini Kaforou

@_myrsini_

6 years

Our interdisciplinary projects on novel host-based #infectiousdisease diagnostics in collaboration with @pgeorgiou_ic @jesusrodman featuring on pages 19/20 of the @ImperialCBIT annual report. #tuberculosisdiagnostics #isitbacterialinfection

Timothy Constandinou

@tgconstandinou

6 years

Pleased to announce the @ImperialCollege Centre for Bio-Inspired Technology @ImperialCBIT Annual Report 2018 is now available in PDF on our website: @Imperialcas @Imperialeee

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Myrsini Kaforou

@_myrsini_

4 years

In other news: Out today @NatureMicrobiol a fantastic piece of work led by @Moritz_Treeck lab @TheCrick on how some malaria causing parasites manage to employ a specific set of proteins to "feel at home" in their host cells. What an illustration by Heledd Davies 🎨⬇️

Moritz Treeck

@Moritz_Treeck

4 years

It's out! The export and expansion of the FIKK kinase family gives some malaria causing Plasmodium species a unique set of effector proteins to interfere with host cell function. This illustration by Heledd Davies did not make the cover, but I love it!

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Myrsini Kaforou

@_myrsini_

4 years

@PERFORM_2020 and @DIAMONDS_2020 are refocusing efforts to tackle #COVID19 . Our European-wide clinical and scientific network is working day & night towards new diagnostic approaches and better understanding of the disease pathogenesis. @EU_H2020 #bigdata #personalisedmedicine

PERFORM

@PERFORM_2020

4 years

From New Challenges to New Solutions. The @PERFORM_2020 and @DIAMONDS_2020 consortia are optimistic their novel #diagnostic approaches can accelerate the understanding of #COVID19 . @acunningID @_myrsini_ @fedemartinon @MTsolia @pablorojoconejo @rgnijman

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Myrsini Kaforou

@_myrsini_

3 years

👇Excellent thread about our new paper on identifying differences and similarities between mouse models of #malaria and malaria disease in humans using blood #transcriptomics . Proud to be part of this team.🙌 #translationalresearch

Aubrey Cunnington

@acunningID

3 years

How should we determine the Relevance of #animal models in #medical research? Our new paper addresses this in #mouse models of #malaria . Should Relevance be added to the 3Rs? (1/14) thread below

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Myrsini Kaforou

@_myrsini_

6 years

@acunningID sharing new exciting insights about severe malaria disease in children obtained via whole blood #dualRNAsequecing looking at the interplay between the host and the parasite @PERFORM_2020 dissemination in Riga #endmalaria @ICE_Malaria @AthinaofAthens @joshuahjlee

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Myrsini Kaforou

@_myrsini_

5 years

The blue sky does help indeed but I don't think I have ever been to a more beautiful campus @Stanford #academiclife

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Myrsini Kaforou

@_myrsini_

5 years

A direct Eurostar train from Amsterdam to London from April 30th. But also a direct service from Rotterdam opens on the 18 May! Just on time for #ESPID2020 - @ESPIDsociety so great!

What it's like onboard the first direct Eurostar train from Amsterdam to London

Passengers no longer have to change at Brussels

www.independent.co.uk

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Myrsini Kaforou

@_myrsini_

9 months

📢 We are looking for a Post-Doc/Fellow in Bioinformatics to work with us on data analysis and modelling for large international projects. Closing 18th of January. More details below:

Myrsini Kaforou

@_myrsini_

10 months

🔔 Job alert 🔔- please share! We are looking for a Research Associate/Fellow in Bioinformatics and Precision Medicine to join our group @ImperialInfect More details and how to apply: #jobalert #bioinformatics #postdoc #omics #dataanalysis #RNASeq

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Myrsini Kaforou

@_myrsini_

5 years

The 4th @PERFORM_2020 annual meeting kicks off at @MerieuxUniv hosted by our partner @biomerieux in Lyon. Looking forward to 3 days full of science, exciting data, lovely food and wine. #Horizon2020

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Myrsini Kaforou

@_myrsini_

5 years

So excited to join @fedemartinon at the legendary @TIPICO_SANTIAGO meeting this year! 👍

TIPiCO 2023

@TIPICO_SANTIAGO

5 years

Myrsini Kaforou @_myrsini_ es una de las científicas más brillantes que conozco, y estará en el #tipicoX para hablarnos de la revolución del diagnóstico de las enfermedades infecciosas a través del huésped.+info en @fedemartinon

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Myrsini Kaforou

@_myrsini_

4 years

Watch @ACheyne33 's fantastic video showcasing her research in the most creative way! A piece of art! 🤩

Ashleigh Cheyne

@ACheyne33

4 years

I attempted to learn video editing/animation to make a video explaining my research for a competition. Although not selected, this was SUCH a fun experience 🥰 that I decided to share it anyway, happy Friday! 🎥🎞️🧬 #scicomm #sciart #Sciartober #evolution #tuberculosis

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Myrsini Kaforou

@_myrsini_

3 years

A fantastic journey & a truly multi-disciplinary collaboration @ImperialInfect @UCLInfectImm @imperialeee @UCLHresearch @BRCinfection @ImperialBRC @OxfordGenomics @Imperial_AID Fantastic teamwork & perseverance @HoKwongLi @jesusrodman @Rishi_K_Gupta @mnoursad @Grampospath 🙌(6/7)

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Myrsini Kaforou

@_myrsini_

5 years

Many congratulations @SanchoShimizu on your FLF!!🎉 Amazing news!! 👍

Imperial Medicine

@ImperialMed

5 years

We are delighted that Dr Vanessa Sancho-Shimizu ( @SanchoShimizu ) and Dr Oliver Robinson have been awarded Future Leader Fellowships by @UKRI_News 🎉

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Myrsini Kaforou

@_myrsini_

5 years

Congratulations little sister @daphne__ka for receiving one of the @ImperialBiz Weekend MBA scholarships! 🎉 And welcome to the club aka @imperialcollege ! #WomeninSTEM

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Myrsini Kaforou

@_myrsini_

4 years

2/2: White bars mean no reports of the variant. But could it be due to lack of surveillance? Are there recent sequencing data or meta-analysis of conventional PCR tests (targeting the S gene) that can suggest if the variant is present in the community? #covid_19gr #covid19gr

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Myrsini Kaforou

@_myrsini_

4 years

A topical study that provides insights into this new syndrome a month after it was first noticed and identified by this amazing clinical team! @ImperialInfect @ImperialAHSC @BRCinfection @lizWWyld @jetpackjeth @PriyenShah86 @GreatOrmondSt @EvelinaLondon

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Myrsini Kaforou

@_myrsini_

5 years

@andrew_mcardle 's first PhD paper out @MicrobioSoc showing abundance estimates in shotgun #metagenomics depend on the selection of #bioinformatic tools & that contamination is the issue, aka the power of mining publicly available data in different ways

Sensitivity of shotgun metagenomics to host DNA: abundance estimates depend on bioinformatic tools...

www.microbiologyresearch.org

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Myrsini Kaforou

@_myrsini_

3 years

A key element in biomarker discovery studies is to have *extremely well defined* patient groups (to use as labels for #MachineLearning ⌨️), also accounting for diagnostic uncertainty. @PERFORM_2020 has developed a new 11-class clinical classification algorithm for febrile children

Ruud G Nijman

@rgnijman

3 years

A long time in the making: 1/ A Novel Framework for Phenotyping Children With Suspected or Confirmed Infection for Future Biomarker Studies

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Myrsini Kaforou

@_myrsini_

4 years

@PennisiIvana @PriyenShah86 @hrjackson_ @rgnijman Dom Coote and Irene Rivero discussing exciting @PERFORM_2020 data during an excellent session #espid2020 @ESPIDsociety - Well done all! 👏

Tobias Tenenbaum

@TenenbaumTobias

4 years

Great diagnotic session. Obevof the best of #ESPID2020 😃

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Myrsini Kaforou

@_myrsini_

6 years

#LINO18 Science walk with #NobelLaureate Sir Richard Roberts of @NEBiolabs - discussed pretty much everything. Gene splicing, bacterial epigenetics, GMOs, public outreach, scientific responsibility, failures, funding, work life balance, brexit. Buzzing afternoon.

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Myrsini Kaforou

@_myrsini_

10 months

🔔 Job alert 🔔- please share! We are looking for a Research Associate/Fellow in Bioinformatics and Precision Medicine to join our group @ImperialInfect More details and how to apply: #jobalert #bioinformatics #postdoc #omics #dataanalysis #RNASeq

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Myrsini Kaforou

@_myrsini_

4 years

Congratulations to @paolo_montaldo and the rest of the team! Blood gene expression does the trick again. RNA profiles measured soon after birth in babies with neonatal encephalopathy predict adverse neurodevelopmental outcome 18 months later. @SciReports

Transcriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy

Scientific Reports - Transcriptomic profile of adverse neurodevelopmental outcomes after neonatal encephalopathy

www.nature.com

Imperial College London

@imperialcollege

4 years

A blood test could diagnose brain damage in newborns just hours after birth The test detects which babies are at risk of serious neurodisabilities like cerebral palsy and epilepsy when deprived of oxygen at birth Find out more 👇

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Myrsini Kaforou

@_myrsini_

8 years

Great opportunity for a fully funded #Bioinformatics PhD in Infectious Diseases @PERFORM_2020 @FoMImperial Apply:

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Myrsini Kaforou

@_myrsini_

5 years

🎵 we are all about vaccines, cause #VaccinesWork ! Amazing performance from Marko Pokorn and his band live @ESPID_Society opening ceremony #ESPID2019 - the bar is set really high for #ESPID2020 👏

ESPIDSociety

@ESPIDsociety

5 years

Our local co-chair, Marko Pokorn, is performing with his band live at #ESPID2019 welcome reception! We don’t do this for living!

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Myrsini Kaforou

@_myrsini_

6 years

#LINO18 is about to kick off! 👏 @lindaunobel

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