Centre for Targeted Protein Degradation @UoDCeTPD Twitter profile

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Centre for Targeted Protein Degradation

@UoDCeTPD

11 months

We're thrilled to announce our line up of confirmed speakers for our Symposium in May 2024! We invite you to apply via the link below. We hope you are as excited as we are for 3 days of science and Scottish fun! Apply->

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Congrats to @Farnaby84 who has received a prestigious Wellcome Trust Early Career Award! This award will: - develop methods for small molecule mitophagy activation - establish an induced proximity chemistry programme to address unmet medical needs in neurodegenerative diseases

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

We have been blown away by all the wonderful messages that we have received in response to our symposium! Thank you! It means a lot to all of us that our delegates had a fantastic time in Dundee and have left inspired to push forward the frontiers of TPD research! #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are delighted to officially launch our Twitter channel. Follow us to keep up to date with the Centre - our research, activity, and opportunities to work with us. Follow us on @LinkedIn as well: #TargetedProteinDegradation #PROTACS

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We invite you to save the date! We will be hosting”Protein Degradation in Focus, a special symposium to celebrate the opening of CeTPD in Dundee” on 19-22 May 2024. Scientific co-organisers, @alessiociulli , Brenda Schulman, @CraigMCrews , @val_spiteri & @CharlCrowe !

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

📖 Our story (a thread): Founded and directed by Professor @alessiociulli , we are the first Centre in the UK with an explicit focus on #TargetedProteinDegradation #TPD #PROTACs #InnovateCollaborateInspire

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Our new toy has arrived! The Ascend Mass Spec from @thermofisher Our senior proteomics scientist Manjula Nagala can't wait to get it installed and use it!

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

A pan-CeTPD team of structural biologist and chemists have published a pre-print revealing the novel CRBN construct, that can be expressed in E.coli without DDB1 and has been validated in biophysical and structural studies. Link:

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Centre for Targeted Protein Degradation

@UoDCeTPD

7 months

Excited to share our latest work that is now available to read in @Nature . News story: #CeTPDCollaborate #TargetedProteinDegradation

“Protein sandwich” could transform cancer drug discovery

A breakthrough class of molecular glue identified at the University of Dundee could pave the way for a new generation of drugs to target cancers and neurodegenerative diseases.

www.dundee.ac.uk

Ollie Hsia

@ollie_lh

7 months

I am thrilled to share that our story on Intramolecular Bivalent Glues has now been published in @Nature . This has been an incredible team effort alongside my co-leads Matthias Hinterndorfer and Angus Cowan, with the support and guidance from @georg_e_winter and @alessiociulli .

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

More symposium plans brewing- this time we have PhD student Tom Webb joining the team to help plan the career's panel that he'll be chairing at our TPD in Focus Symposium! T-23 days! @alessiociulli , @CharlCrowe & @val_spiteri

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

We are delighted to receive £2 million to develop the next phase of CeTPD as part of the Technopole site as announced by Jacob Young, Parliamentary Under Secretary of State, (Levelling Up) this week. Levelling Up Fund to benefit University initiatives

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Our Director @alessiociulli was elected as a Fellow of @RoyalSocEd last month. This was in recognition of their impact in improving the world around them. Alessio is a world-leader in #TargetedProteinDegradation #ThrowbackThursday

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

And we're finally back! Kicking off the second session at #TPDFocus with an incredible talk by @DanNomura : "Reimagining Druggability Using Chemoproteomic Platforms." 🌟🔬 #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

Fantastic turnout this morning for the Women in TPD networking breakfast held as part of the Protein Degradation in Focus Symposium. @WomenInTPD , #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

We have 300 goodie bags packed and ready to go for our delegates! @alessiociulli is clearly very excited about his new reusable shopping bag! Big thanks to the CeTPDers who helped pack these!

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Centre for Targeted Protein Degradation

@UoDCeTPD

7 months

We are delighted to share that our Director Professor @alessiociulli is part of the Cancer Grand Challenges KOODAC team! The team will use protein degradation strategies to target previously undruggable drivers of children’s cancers.

Cancer Grand Challenges

@CancerGrand

7 months

📢 Announcing five new global #CancerGrandChallenges teams! 📢 We're thrilled to announce five new teams, each receiving up to $25m over five years to tackle some of cancer's toughest challenges. Meet the teams: @CR_UK @theNCI

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

@CraigMCrews is kicking off the #TPDFocus symposium with his keynote talk: "Tik-TAC-Toe: A Heterobifunctional for Every Need." #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are seeking applications for up to 4 Principal Investigators in the field of #TargetedProteinDegradation to join our new Centre @dundeeuni Info & to apply (external candidates): (internal: ) #PrincipalInvestigator #AcademiaJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are seeking applications for up to 4 Principal Investigators in the field of #TargetedProteinDegradation to join our new Centre @dundeeuni Info & to apply (external candidates): (internal: ) #PrincipalInvestigator #AcademiaJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Next, our "local CeTPD player" @farnaby84 takes the stage with his talk: "Pursuing Targeted Protein Degradation for Investigating CNS Disease." #TPDFocus 🧠

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We shared the news, now read the story! Will Farnaby @farnaby84 has been awarded 5 years of funding from Wellcome to find new ways to discover effective treatments for neurodegenerative diseases. #InnovateCollaborateInspire #TargetedProteinDegradation

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

It's all go go go at CeTPD HQ! Big thanks to our admin team for coordinating all the logistical chaos for TPD in Focus! T-3 days!

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

We’ve just had an incredibly inspiring Careers in Academia & Industry Network Panel at #TPDFocus ! Discussed work-life balance in science with @BekkyFeltham , @ollie_lh , #IngridWertz , and @DanNomura . Thank you all for the valuable insights!

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

More symposium planning madness this evening this time we're joined by @ales_salerno CeTPD scientist who has been amazing and has formatted our conference booklets 😊 @alessiociulli @val_spiteri

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

The last session of #TPDFocus has come to an end! 🌟 Chaired by Valentina Spiteri, we had great talks from #IngridWertz , @danetteldaniels , #AngelaCacace , @EndriuT , @VesnaVetma , and wrapping up with #RebeccaStevens .

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

The #TPDFocus second day has just begun! Dive into Session 1: Therapeutic Development 🔬chaired by @UoDCeTPD director @alessiociulli ! 🌟 Let the first session begin!

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Meet our Protein Degradation in Focus Symposium keynote speakers: @CraigMCrews PhD is the John C. Malone Professor of Molecular, Cellular & Developmental Biology at Yale and will present the talk 'Tik-TAC-Toe: A Heterobifunctional for Every Need' #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

9 months

Happy New Year! Here at CeTPD we're gearing up for the year ahead and we're looking forward to welcoming the community to Dundee in May (19th-22nd)! If you haven't applied yet there's still time! Deadline for applications is the 15th of Jan! Apply -->

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

The last day of the symposium has just started! #TPDFocus Chaired by the amazing #BrendaSchulman , today's Discovery Chemistry & Design III session kicks off with @alessiociulli as the first speaker, followed by @CrisMayorRuiz and #StefanKnapp .

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are excited to be hosting Hanna and Johanna for the next two weeks as part of the Auricher Wissenschaftstage work experience program! They'll experience some of our work first hand, running their own experiments and helping us with ours. #InnovateCollaborateInspire

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

TPD in Focus Symposium team busy this evening make sure the event is perfect for our delegates joining us in May @alessiociulli @CharlCrowe @val_spiteri Louise McGreavey @UoDCeTPD

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We had a great time welcoming @drcmwoo to @UoDCeTPD as part of our Seminar Series. We had a jam-packed two days with plenty of science and idea sharing, as well as a hike along the beautiful Fife coast and a CeTPD BBQ!

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Some of our team are out in Barcelona for the event on Proximity-inducing pharmacology: Targeted protein degradation and beyond. Will Farnaby, Alessio Ciulli and Angus Cowan are speaking during this mornings first session. #InnovateCollaborateInspire #TargetedProteinDegradation

Alessio Ciulli

@alessiociulli

1 year

Having great time strolling in Barcelona getting ready for Monday’s #BarcelonaBiomed #TPD conference and looking forward to meeting many friends and colleagues soon! @val_spiteri @Mark_A_Nakasone @ollie_lh @farnaby84 @AlenaKro @UoDCeTPD

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

The second session of today's #TPDFocus , chaired by CeTPDer #KirstenMcAulay , was outstanding! 🙌 @iDikic2 kicked things off, followed by insightful talks from @drcmwoo , @Michael_A_Erb , @johanna_h , and @biomiko . Thank you all for your presentations!

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

We're excited to welcome you all to Protein Degradation in Focus Symposium hosted by CeTPD. Come and register at WTB atrium now! Drinks reception will start at 5pm. Looking forward to seeing everyone one there! #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Meet our Protein Degradation in Focus Symposium keynote speakers: Professor @alessiociulli PhD, Director of @UoD_CeTPD who will give a talk entitled 'We keep degrading! CeTPD’s past, present and future' #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

It's a sad week here @UoDCeTPD as we say goodbye to our Chemistry Associate Researchers from the ACBI team 😪 We wish them a great summer break, and all the best with their PhDs @StrathChem and @GSK , and for @AdamPinto12 , back with the @Farnaby group

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Centre for Targeted Protein Degradation

@UoDCeTPD

2 months

Great attendance for @val_spiteri & @Mark_A_Nakasone interactive talk, 'Applying #cryoEM to understand chemically induced ternary complexes for #TPD & Glues' as part our CeTPD Seminar Series. As always, the talks are followed by an opportunity to chat as well as eat pizza!

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

Day 2 of #TPDFocus just started! 🎉 This morning, we were captivated by amazing talks at the Molecular Mechanisms & Biology II session. Huge thanks to our session chair @CraigMCrews and brilliant speakers #BrendaSchulman , @eric_fischer and @BekkyFeltham ! 👏🔬✨

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

🚨 We are hiring a Chemist for the @AlessioCiulli / @Boehringer team at CeTPD. Join our dynamic drug discovery team and help us find effective PROTACs for oncology targets. Find out if you'd be right for this position and apply at #ChemJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

7 months

We are honoured that our AC-BI team have been nominated for the Cancer Research Horizons Further, Faster, Together Industry-Academia Award in recognition of the collaboration team's excellence and achievements. #CeTPDCollaborate #TargetedProteinDegradation

Cancer Research Horizons

@CR_Horizons

7 months

🏆 Hot off the press: the shortlist for our Innovation & Entrepreneurship Awards 2024! Congratulations to everyone – we’re looking forward to celebrating your achievements at the Ceremony on 20 March. #IEAwards2024 @oxengsci , @pentabind , @uclcancer , @EdinCRC , @UniofNewcastle ,

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Now on stage: @FleurMFerguson revealing the secrets to "Interrogate the Druggable Proteome with Proximity Pharmacology." #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

6 months

The CeTPD March 2024 CeTPD journal club issue is now live! Thanks to our amazing editors: @Bkgadakh @NKKarolak @RobertaIbba5 #openaccess #TPD #journalclub @UoDLifeSciences @alessiociulli @farnaby84 @Holmqvist89 @DeLaCuadraBaste

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

We approach the final talk of the day at #TPDFocus ! #AlejandroRojas -Fernandez together with his #alpaca take the stage to present his work titled "Specific Proteolysis Mediated by a p97-Directed Proteolysis-Targeting Chimera (PROTAC)

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Centre for Targeted Protein Degradation

@UoDCeTPD

11 months

Check out our recently published work on a new method for targeting SOCS2 with a phosphotyrosine-masked covalent ligand. To find out more about this fabulous work and it's impact on the field of TPD, you can also read the press release Congrats team!

'Trojan Horse’ chemical tool allows researchers to target ‘undruggable’ proteins

University of Dundee researchers have developed a new molecule that is able to target and bind to a protein class previously considered undruggable by using a masking technique to enter the cell

www.dundee.ac.uk

Nature Communications

@NatureComms

11 months

@alessiociulli lab and colleagues develop phosphotyrosine-based covalent ligands of the E3 ligase SOCS2 using structure-based design. A pro-drug approach yields cell active inhibitors that block SOCS2 substrate recruitment

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

Fancy some new TPD literature to read? Check out the January 2024 CeTPD journal club issue: Edited by: @Alex_Hallatt @DyylaanL & @DeLaCuadraBaste #openaccess #TPD #journalclub @UoDLifeSciences @alessiociulli @farnaby84 @Holmqvist89

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Centre for Targeted Protein Degradation

@UoDCeTPD

11 months

We were delighted to welcome @GeorgeFreemanMP , Minister of State for @SciTechGovUK to Dundee to officially open the CeTPD. This gave us the opportunity to celebrate our journey so far, and also share our world-leading research and vision for the future of #TPD

George Freeman FRSA MP

@MPGeorgeFreeman

11 months

1st stop on Day 1️⃣ of NE Scotland 🏴󠁧󠁢󠁳󠁣󠁴󠁿 #R &DClusterTour: The Centre for Protein 🧬 Degradation UoDCeTPD @UoDLifeSciences @DundeeUni to formally open the new Lab w Prof @alessiociulli 👏 & #LifeScience 💊 industrial partners @AmphistaThera @Boehringer_UKI @Exscientia

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

Dundee in the sunshine. Lovely day for a drone flight over CeTPD, SLS and the silvery Tay! Thanks to Kean's for making sure our roof stood up to the recent storms.

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

Diane from our admin team, is hosting a bake sale fundrasier ate CeTPD to send her grandddaughter who is competiting in the Cheerleading Worlds with her team the Dundee Diamonds! CeTPDers are thrilled to be able to support thislocal team and have some cake too! Go Diamonds!

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

We are recruiting for 4 PI/Group Leaders. We seek applications from individuals with research programmes within the field of #TargetedProteinDegradation Full details & to apply:

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

We hope you had an amazing time at the #TPDfocus symposium. Catch up on other TPD highlights in April's Journal club now available 👇 Thanks to our amazing editors: Gemma, Tom and @AL_Harris20 #openaccess @UoDLifeSciences @alessiociulli @farnaby84

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Get ready for some Intramolecular Bivalent Glues at #TPDFocus ! @_matthias_h is about to rock the stage with his talk on "Targeted Protein Degradation via Intramolecular Bivalent Glues." 🔥🔬

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Centre for Targeted Protein Degradation

@UoDCeTPD

10 months

It's beginning to look a lot like Christmas around CeTPD! Our wonderful admin team decorated the entryways, and we had a nice t(r)ee break this afternoon to decorate our common room now that winter has arrived 🥶

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Centre for Targeted Protein Degradation

@UoDCeTPD

6 months

One month to go until our Protein Degradation in Focus Symposium begins! We can't wait to welcome you to Dundee. Please use the symposium hashtag #TPDFocus to share your experiences with us during the event! #TargetedProteinDegradation

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

The 2023 May Journal Club issue is now live at: Amazing job to all our editors Lourdes, @ACorreasa , and @Mark_A_Nakasone with contributions from @CgSelma and a great illustration from @psillustrator . #TPD #TargetedProteinDegradation #CeTPDInspire

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

🚨 Job position available! We are hiring a cell biologist for the @AlessioCiulli @Boehringer team at CeTPD, studying the effects our degraders have on cancer targets. Sound like a good fit for you? Then apply to position UoD728 #BioPostDoc #BioJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

11 months

We've recently disclosed our work in collaboration with @Boehringer in developing pan-KRAS degraders. Congrats to all of the team members involved in this thorough study which is sure to help with the search for future treatments of KRAS driven cancers

Targeting cancer with small molecule pan-KRAS degraders

Despite the high prevalence of cancers driven by KRAS mutations, to date only the G12C mutation has been clinically proven to be druggable via covalent targeting of the mutated cysteine amino acid...

www.biorxiv.org

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We we're delighted to show @djohnsonmsp around CeTPD this week! Daniel was really intrigued by our work, asking @alessiociulli a lot of great questions during a tour of our labs. Thanks for visiting us Daniel! #InnovateCollaborateInspire

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

We celebrated Burns Night, with a Scottish & international pot luck dinner. Conner performed the traditional address to a Haggis & Sohini sang Phule Phule Dhole Dhole by Bengali poet Rabindranath Thakur, set to the tune of Robert Burns’ song Ye Banks an’ Braes o’ Bonnie Doon.

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Up next at #TPDFocus with #BenjaminLEbert ! He'll be unveiling the latest on targeted protein degradation for transcription modulation. 🧬 🎯

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

Wrapping up Day 2 of #TPDFocus with an incredible final session! @georg_e_winter kicked things off, followed by stellar talks from #NicolasThom ä, @gpsapkota , @CharlCrowe , #JihoPark and @DavidYNie . Thanks to all the speakers for an inspiring day!

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are seeking applications for up to 4 Principal Investigators in the field of #TargetedProteinDegradation to join our new Centre @dundeeuni Info & to apply (external candidates): (internal: ) #PrincipalInvestigator #AcademiaJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

4 months

Our Director Alessio Ciulli is currently at the Karolinska Institute. We look forward to hearing about the forum and his other recent trips when he returns.

Alessio Ciulli

@alessiociulli

4 months

So looking forward to visiting @karolinskainst and joining the @scilifelab facility forum tomorrow, exchanging experiences and learnings with science innovation and building infrastructure and facilities @UoDCeTPD @UoDLifeSciences

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Meet our Protein Degradation in Focus Symposium keynote speakers: Prof. Brenda Schulman, Ph.D. from Research Department Molecular Machines & Signaling at the Max Planck Institute of Biochemistry will talk on 'Signaling through the ubiquitin-proteasome system.' #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

10 months

The October journal club is now live! Check it out for snapshots of recent TPD research, edited by @val_spiteri , @DrKelpies and Mokhitli Morake #openaccess #TPD #journalclub @UoDLifeSciences @alessiociulli @farnaby84 @yutingcao1018 @Holmqvist89

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

🚨 Postdoctoral position available! Biology postdoctoral position available in the Farnaby group ( @farnaby84 ) within CeTPD, to study induced proximity for treating CNS diseases. Sound like it would suit you? Then apply to position UoD739 at #BioPostDoc

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Check out our July 2023 CeTPD journal club issue, covering some of the latest work in TPD. Edited by Angus, @ShakilK2709 and @xingui_liu #openaccess #TPD #journalclub @UoDLifeSciences @alessiociulli @farnaby84 @yutingcao1018 @Holmqvist89

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Fancy some new TPD literature to read? Check out the September 2023 CeTPD journal club issue: Edited by: @HirotakeFuriha1 , @lukemsimpson & Qingzhi Zhang #openaccess #TPD @UoDLifeSciences @alessiociulli @farnaby84 @yutingcao1018 @Holmqvist89

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are delighted to be part of Team KOODAC for the #CancerGrandChallenges Our international team aim to develop oncoprotein degraders to target the drivers of solid tumours in children. #CeTPDCollaborate #TargetedProteinDegradation

Cancer Grand Challenges

@CancerGrand

1 year

📣 BREAKING NEWS 📣 We're excited to announce the 12 teams shortlisted for a #CancerGrandChallenges award. Each team has the chance to receive up to $25m to make radical progress against cancer’s toughest challenges. Discover the teams: @theNCI @CR_UK

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

🚨 We are hiring a Senior Scientist in Mass Spectrometry and Proteomics at CeTPD! If you are an experienced proteomics scientist, interested in working in a dynamic research environment, take a look at the opening and apply. #InnovateCollaborateInspire

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Centre for Targeted Protein Degradation

@UoDCeTPD

7 months

Good luck tonight to our AC-BI team who have been nominated for the Cancer Research Horizons Further, Faster, Together Industry-Academia Award in recognition of the collaboration team's excellence and achievements. #CeTPDCollaborate #TargetedProteinDegradation #IEAwards2024

Cancer Research Horizons

@CR_Horizons

7 months

The wait is over! Congratulations to all the incredible individuals who made it to the #IEAwards2024 shortlist! 🌟Stay tuned for a live unveiling of the winners, tomorrow 20 Mar at 6pm and for a memorable evening celebrating innovation, entrepreneurship & excellence.

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Did you know that Dundee is the sunniest city in Scotland!? #SunnyDundee #InnovateCollaborateInspire

Giorgia Kidd

@Justgiorgia

1 year

Spring has sprung here @UoDCeTPD 😎🐥

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Centre for Targeted Protein Degradation

@UoDCeTPD

7 months

Aitana De La Cuadra Baste, @DeLaCuadraBaste , sharing our outreach activity in 2023 @UoDLifeSciences Annual Research Symposium. We won a School Public Engagement Prize in recognition of this work. #CeTPDInspire #TargetedProteinDegradation

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

The first day of our Protein Degradation in Focus Symposium has arrived! Today's schedule: 🕒 15:00 - 18:30: Registration 🕔 17:00 - 18:30: Networking Drinks 📍 Atrium, Wellcome Trust Building, School of Life Sciences #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

10 months

The latest TPD literature all in one place. The November journal club is now live! Thanks to this month's editors Adam Pinto, Alena Kroupova & Nur Kocaturk @adampinto12 @nurkocaturk #openaccess #TPD #journalclub @UoDLifeSciences

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Centre for Targeted Protein Degradation

@UoDCeTPD

6 months

We're thrilled to be featured in a display @McManusDundee @UoD_Museums !

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Congratulations Lexie!

Goss Group

@GossGroup

1 year

It was a pleasure to examine, with Ian Gilbert FRSE, Lexie Harris’ thesis work today @UoDCeTPD @UoDLifeSciences on a cool, new PROTAC. Beautiful synthesis by Lexi, enabling development of a powerful new tool. Many congratulations to Lexie and the inimitable @alessiociulli FRSE

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

#MartinVolker is about to take the stage, unveiling insights on "Homo-BacPROTAC-Induced Degradation of ClpC1 as a Strategy Against Drug-Resistant Mycobacteria."

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

As our Protein Degradation in Focus Symposium approaches, here's a fact about Dundee. 😎 Bring sunglasses! Dundee is the sunniest city in Scotland! Here's our Director @AlessioCiulli & Operations Lead Louise with Mike from @FallonesPizza being dazzled by the sun! #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

CeTPD has been awarded the bronze award in @UCL 's Laboratory Efficiency Assessment Framework 🍃 Thanks to our Green Team and wonderful lab managers for helping to implement changes to make CeTPD greener! Now onto working towards the silver award 🥉

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We had the privilege of sharing our science with the wider community this week, both at Menzieshill community centre, and in CeTPD with a visit from a group from Dunkeld. We loved the outreach opportunities and can't wait for the next ones! #CeTPDInspire #CeTPDOutreach

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Two weeks to go until our Protein Degradation in Focus Symposium begins! Please use the symposium hashtag #TPDFocus to share your experiences with us during the event! #TargetedProteinDegradation

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Lovely spring morning here at CeTPD! Made all the better by the mountain of fresh strawberries in our common room from local @BalungieFarm , courtesy of our Senior Biology Tech @dmcassidy1 !

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Last week, Will Farnaby had a fantastic visit to Santiago De Campostela where he led a workshop at the #MedChem @SocEspQuimTerap @Galchimia Summer School.

SEQT

@SocEspQuimTerap

1 year

Day 1 - #SummerSchoolSEQT2023 Workshop 1. Chemical Biology. Targeted Protein Degradation Dr. William Farnaby @farnaby84 from CeTPD, @dundeeuni

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Centre for Targeted Protein Degradation

@UoDCeTPD

3 months

We are excited to be hosting the #EUbOPEN annual meeting in Dundee this September! Looking forward to hearing updates from all the partner sites and work package leaders on probe development and more. #OpenScience #EUbOPEN2024

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Visit CeTPD as part of @DoorsOpenDays 2023 on the 23rd September from 10 am - 2 pm! We will have family friendly activities outside, and lab tours running during the day. To find out more, visit and sign up for the tours here

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Centre for Targeted Protein Degradation

@UoDCeTPD

8 months

We were delighted to be recognised for our public engagement work over the past two yrs at the School Awards presentations. We have been on a productive journey from establishing the group, creating activities/events based on our research and engaging with a wide range of people.

UoD Life Sciences

@UoDLifeSciences

8 months

@mrcppu @WCAIRDundee Brian Cox Prize for Excellence in Public Engagement with Research 🌟 Team of the Year was awarded to the @UoDCeTPD Outreach Team Highly Commended: @DDU_Dundee Tuberculosis Team

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Centre for Targeted Protein Degradation

@UoDCeTPD

7 months

The Feb 2024 CeTPD journal club issue is now live! Thanks to our amazing editors: @liamtommartin92 @krolssimon & @elishamccrory_ #openaccess #TPD #journalclub @UoDLifeSciences @alessiociulli @farnaby84 @Holmqvist89 @DeLaCuadraBaste

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

🚨 We are hiring a Senior Scientist in Structural Biology/Biophysics for the @AlessioCiulli @Boehringer team at CeTPD. You can help lead our team to ground-breaking discoveries! Find out if you'd be right for this position and apply at #BioJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Dundee science legend and "local lad", #RonaldHay , takes the stage at #TPDFocus with his talk: "Targeted Degradation of the Promyelocytic Leukemia Protein by Arsenic."

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

After a refreshing lunch break and a poster session, we're back with more excitement at #TPDFocus ! 🚀 Kicking off the second session: Discovery Chemistry & Design I, chaired by #DafyddOwen .

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We thank SULSA & our other events sponsors @promegauk & @TakaraBioUSA for supporting our first meeting which involved 120 early career participants from the UK & Europe. If you would like to join our network, drop us a message here #CeTPDCollaborate #TargetedProteinDegradation

SULSA

@SULSAtweets

1 year

Next is Valentina Spiteri @val_spiteri @dundeeuni for their event on Targeted Protein Degradation for early career researchers Exciting to see this meeting has already led to an international research placement at @UoDCeTPD

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

We are seeking applications for up to 4 Principal Investigators in the field of #TargetedProteinDegradation to join our new Centre @dundeeuni Info & to apply (external candidates): (internal: ) #PrincipalInvestigator #AcademiaJobs

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Fantastic news to be see the University of Dundee named as top for supporting spinout businesses. Proud to see Amphista Therapeutics Limited, co-founded by our Director Professor @alessiociulli , named in the report as a contributor to Dundee's success! #CeTPDInnovate

UoD Life Sciences

@UoDLifeSciences

1 year

The University of Dundee has been named the UK’s best for supporting spinout businesses, according to industry-leading analysis by @OctopusVentures Companies specifically highlighted in the report include School spinouts @exscientiaAI & @AmphistaThera

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

The grand finale of this second session is here at #TPDFocus ! 🌟 @katmcphie takes the stage with her work titled "Chemical Biology Approaches to Explore the Ligandability of TRIM E3 Ligases"

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Centre for Targeted Protein Degradation

@UoDCeTPD

10 months

Registration for our Symposium in May will be open till the 15th of January 2024. Here's a reminder of our amazing line up! We're looking forward to welcoming the TPD community to Dundee! Dates: 19th-22nd May 2024. More information & apply here:

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

Next up is @LauraSerini 's talk: A predictive screening platform for targeted degradation of cell surface proteins using SureTACs. #TPDFocus

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Centre for Targeted Protein Degradation

@UoDCeTPD

5 months

#TPDFocus , @Keribackus is next with her talk on "Chemoproteogenomic Approaches to Stratify the Functional and Therapeutically Relevant Proteome."

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Centre for Targeted Protein Degradation

@UoDCeTPD

1 year

Last July, we announced a partnership with @BioTechne to commercialise technology developed @dundeeuni that enhances the understanding of undruggable diseases. BromoTAG was developed by Conner Craigon & Adam Bond (📸 ). #ThrowbackThursday #Collaborate

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