Thomas Agoritsas, MD PhD @ThomasAgoritsas Twitter profile

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Thomas Agoritsas, MD PhD

7 months

How to move from consensus-based to trustworthy evidence-based guidelines when comparing >50 competing interventions? Our innovative approach led by @magicevidence & @JasonWBusse published as as #RapidRec in the @bmj_latest with evidence summaries in interactive #MatchIt tool👇

Gordon H. Guyatt

@GuyattGH

7 months

A recent innovative guideline addressing chronic temporomandibular pain demonstrates how to deal with a large number of competing interventions in a network meta-analysis and use GRADE to generate trustworthy recommendations.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

5 months

@HarvxrdPSC So Harvard is no longer a University.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

@alexmeshkin Another example of “survival bias”. I haven’t had a problem, so the problem doesn’t exist.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Monkeypox is NOT a disease limited to MSM. It’s not about current likelihoods, it’s about mechanisms of spread, and the fact that no humans live in silos. One has the right to think intelligently, instead of coping through constant minimization. We should have learned our lesson.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

10 months

@BFMTV “Contreversé” ?!? “Émigration” ?!?Quelqu’un relit vos dépêches? Merci d’éditer au plus vite.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 months

@maximeguay06 Aïe aïe aïe. Quand même beaucoup de déni. Qu’il faille sortir d’un blanc/noir, et reconnaître la grise réalité, oui. Mais douter à ce point de l’extrême souffrance actuelle, de tant d’enfants, est un déni mortifère.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Profoundly #ASHAMED of our #Swiss 🇨🇭citizens in #Rapperswil manifesting against #COVID19 mitigation, while the pandemic rages around the globe killing thousands this very instant.We must reflect on what we did wrong as a collective to allow such PROFOUND STUPIDITY & SELFISHNESS!

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

#omicron : 5 times milder in 20 times more people: 4 times worse. We must NOT lower our guard! Early assessment of the clinical severity of the SARS-CoV-2 Omicron variant in South Africa | medRxiv

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

#Switzerland 🇨🇭I’m sorry to say this is coming next here if we don’t react decisively. Have far too many cases. #COVID19 variants spreading. Frontline colleagues are not lying, this is really bad. Vaccinations campaigns should speed up @alain_berset @BAG_OFSP_UFSP @Hopitaux_unige

Lewis Goodall

@lewis_goodall

4 years

Another member of staff from a London hospital: “Things are a mess. Treatment in ambulances, oxygen ran out the other day. It’s horrid. The whole hospital is full of Covid. This is worse than the 1st wave and is going to get worse because the public don’t realise how bad it is.”

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

New randomized trial in @JAMA_current on single high dose of Vitamin D3 (200'000UI) in moderate to severe COVID19: no significant reduction of hospital length of stay ⌛️(or secondary outcomes of mortality, admission to ICU, mechanical vent.) 👉

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Un rôle clé des #parents est de protéger les #enfants et leur permettre de grandir dans un environnement favorable.Banaliser les dangers qui peuvent les atteindre en les relativisant ou minimisant par fausse réassurance, n’aide en rien. Une #pand émie ne se gère pas par idéologie.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

@BAG_OFSP_UFSP im confused. I went through your twitter threads to look for news about #monkeypox strategy: campaigns, vaccination, treatments. I saw nothing. You have public responsibility to address epidemics & emergencies as Monkeypox, please act accordingly. We are watching.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

@BallouxFrancois The objective is to minimize harms. Not our so-called understanding of a fast-forward way to endemicity in our hopes of resolution. It is presumptuous to make “bog-standard” claims in this pandemic, so please consider not making them. A helpful read if you haven’t seen it yet👇

Aris Katzourakis

@ArisKatzourakis

3 years

My piece on endemicity for @nature . I wrote about the use and misuse of this term, the assumptions it is often associated with, and how we can help shape the years to come.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

#Covid is continuously adding heavily to the burden of all our patients. And it is once again draining our hospital resources. The impact is massive. The silence of any political voice, as reflected in the media, is astounding. It blocks everyone from any meaningful action.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

All data confirms the high impact of #LongCovid , for individuals, health care systems and society. This is not speculation on possible effects of lockdowns and debates around freedom. Just actual EVIDENCE. Need to vaccinate largely before lifting mitigation measures @FLAHAULT 👇

Eric Topol

@EricTopol

3 years

Just published @nature The largest study of post-covid sequelae, >70,000 hospitalized, >13,000 out-patients, with controls, characterizing the significant risks across all organ systems #LongCovid

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

@jk_rowling Everybody should have legal rights and protection. This includes trans people, and doesn’t threaten anyone else’s rights. Seeing that as a threat is indeed the problem, and this perception is either based on ignorance, a profound misunderstanding of these issues, or transphobia.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Increasingly think a #ZeroCovid strategy may well end up being not only a quickest but perhaps our only way out of this nightmare. This would require much more economical support and political commitment to not let anyone further down. @FLAHAULT @samiahurst @EckerleIsabella

Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Confirmed higher estimates transmissibility by +50-70% for 501Y & B.1.1.7 in #Switzerland 🇨🇭 leading in #Geneva . This means the current strong measures barely contain hospitalizations & circulation continues. Not a time to let go of them, unless one is looking for a high 3rd wave.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Comme attendu, les infections #Covid - meme #omicron - augmentent le nombre d’enfants atteints de syndrome inflammatoire multi-systémique #p édiatrique #pims #misc 🦠👶 @GrazioliSerge @Hopitaux_unige @RadioTeleSuisse 👉

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

10 months

@swilkinsonbc Story seems still on line in the Times. Where does it show that it is retracted?

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Une maladie inexistante auparavant, devenant le 3e tueur. Et certains viennent redire qu’on l’a trop prise au sérieux (l’inverse serait vrai). Encore des milliers de décès par semaines dans le monde. Encore un brassage de variants causant vague après vague, traités par le mépris.

Antoine FLAHAULT

@FLAHAULT

2 years

“Le #COVID19 a causé 12,2% des décès en Suisse en 2020. La maladie représente ainsi la troisième cause de mortalité derrière les maladies cardiovasculaires (26,9%) et le cancer (22,2%), indique ce lundi l’Office fédéral de la statistique (OFS).”

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Now folks what’s the real problem in Switzerland with the vaccines? Does anyone actually know? Is it some anthroposophical legacy affecting everyone’s judgment? Little uptake, lots of irrationals worries, praise of nature infections without vaccinal protection, lack of access 🙇🏻‍♂️

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

« La Suisse est le quatrième plus important foyer de covid du monde » 🇨🇭🥇😣 Depuis le temps qu’on le dit. Nos hôpitaux le sentent, et nos malades aussi. #D éni

La Suisse est le troisième plus important foyer de covid du monde - Le Temps

En ce qui concerne l’incidence des nouveaux cas sur sept jours, la Suisse est actuellement au 3e rang mondial. Mais au vu de la tendance épidémique et de sa stratégie de tests de dépistage, le pays...

www.letemps.ch

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

No surprise really. We’ve worked in hospitals throughout the pandemic. You can’t be surprised.

Blick 

@Blickch

2 years

Epidemiologen rätseln wegen Übersterblichkeit: Bereits 3000 Todesfälle mehr als erwartet in diesem Jahr

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

@itosettiMD_MBA We should never have stopped on the first place.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Same happens here in Switzerland 🇨🇭 And lot of unreasonable and misguided pressure to lift off the measures, dismissing these data. Very much like the mistakes of past summer. 😔

Dr Zoë Hyde

@DrZoeHyde

4 years

Concerning data from Germany, showing an epidemic within an epidemic. The total number of new cases is falling, but variant cases are rising, because the current measures are insufficient to control more transmissible variants. This is likely happening elsewhere in Europe, too.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Two main findings: 1. Confirmatory but vaccine-induced myocarditis leads to rapid recovery, with no impact on ❤️ function. 2. Occurs in those with autoimmune predisposition, so probably reveals that predisposition. Covid would likely reveal it too… likely with more implications.

CircImaging

@CircImaging

3 years

8 cases of covid-19 vaccination associated myocarditis showed a male predominance, autoimmunity predisposition, preservation of systolic function and good recovery @OHavakuk @DanaViskin @tasmc1 @venkmurthy @ZainabASamad #AHAJournals

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Likelihood of hospitalization in children seems increase (UK data, now US data) Time to change our narrative about risk in children?

Eric Topol

@EricTopol

3 years

And now this @MartinSavidge @ejleven @CNN via @tmprowell

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Worrying high estimates of #LongCovid in #Switzerland 🇨🇭 , perhaps reaching up to 33% of infected #outpatients (meaning also younger, healthier populations) @LongCovidSOS @apresj20 #longhaulers @trishgreenhalgh

CoronaZero simongehren.bsky.social #LongCovidAlly

@CoronaZeroCH

4 years

Ongoing #LongCovid study at the University Hospital Lausanne / #Switzerland : A third of non-hospitalized (!) #Covid19 -patients (average age 40 yrs.) have ongoing symptoms after 8 weeks. Herd immunity is a medical experiment. I do not consent. #ZeroCovid

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

10 months

@GDarmanin Un vote honteux. Politiquement et humainement inexcusable.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

❌Affirmation mensongère et méprisante de #Nidegger @RadioTeleSuisse @PhilippeRevaz "..qu'un simple écoulement nasal qui n'a avec #Omicron envoyé personne se faire entuber” Merci pour nos patients #omicron INtubés aux soins intensifs @Hopitaux_unige

19h30 - Play RTS

www.rts.ch

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 months

@Europe1 @BHL Chute libre. Posture indéfendable, d’ailleurs on cherche encore les argument de BHL… inaudibles car absents.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

5 months

@al_petel Quel positionnement grotesque. Vous oubliez le sujet même, à dessein, semble-t-il. Revenez sur terre, en particulier la où les corps d’enfants se font déchiqueter par les bombes. Pas celui de la politique locale dans sa tour d’ivoire.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

O M I C R O N I S N O T M I L D ⚰️ (And those who claim it should urgently reflect on their biases)

BNO News

@BNOFeed

3 years

BREAKING: U.S. reports 3,895 new coronavirus deaths, one of the highest since the pandemic began

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

📢 Our paper on #Healthcare Workers #LongCovid #PostCovid #PASC @Hopitaux_unige ⚠️Symptoms & functional impairment ⬆️ than general population. Concerning given their essential role in caring for all 👉 🙏 @mayssamnehme @iguessous #Vetter @LaurentAFKaiser &👇

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

🚨2 UPDATES in our @WHO #LivingGuideline on #COVID19 on: 1/ #JAKinhibitors ( #baricitinib ) for severe 2/ #Sotrovimab for non-severe & high-risk (also for #Omicron ) 🔗 @bmj_latest 👉 @WHO 👉 @theMAGICapp 👉

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

10 months

@Hamzah_1948 😣 The terrible effects of dehumanization, when a child’s life is not sacred anymore, and the other is considered less human, and unworthy of living. There is now plenty of such shameless statements on the web. This is unimaginable. We should all be doing everything in our power

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

🚨Our updated @WHO #LivingGuidance on #COVID19 now adding recommendation on #Monoclonal_Antibodies #Casirivimab & #Imdevimab ( #REGEN_COV ) 👉 👉 #MichaelJacobs @Bram_Rochwerg @PerVandvik @diazjv @bmj_latest @will_s_t

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

“Les patients #COVID19 des HUG sont de plus en plus jeunes” @Hopitaux_unige 👉

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Depuis le temps qu’on le dit… Les chiffres de l’OFSP ne sont d’aucune fiabilité👎 Nos hôpitaux ont réellement été débordés (n’en déplaise à certains) avec un impact sur tous nos patients peu quantifiable. 👉🚨Hospitalisations liées au Covid sous-estimées

Pandémie – Hospitalisations liées au Covid sous-estimées

En 2020, on a dénombré 20’000 hospitalisations à cause du coronavirus. Or les statistiques tendent à montrer qu’il y en a eu au moins 31’000.

www.20min.ch

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

«C’est bon, je me suis testé, ce n’est pas le Covid»: pourquoi vous avez tort -

«C’est bon, je me suis testé, ce n’est pas le Covid»: pourquoi vous avez tort - Heidi.news

Un autotest négatif, preuve qu'on n'a pas le Covid? Le raisonnement est fréquent, mais faux: ces tests sont des passoires, a fortiori pour détecter le variant Omicron.

www.heidi.news

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

5 years

Our new #RapidRecs @bmj_latest : #Thyroid #hormones (levothyroxine) should not be routinely offered to adults with mildly underactive thyroid gland (subclinical hypothyroidism) @MiekeVer @TrudyBekkering @theMAGICapp @Hopitaux_unige @will_s_t @HEI_mcmaster

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

@Inadarkwood @itosettiMD_MBA A dangerous moral shift because we’ve been unable to deal with a pandemic effectively. Reading that, and witnessing it, does break my heart 💔 Of course disabled people’s lives matter, and we should all remember it! Disability can happen to either of us and our loved ones.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Quite true. The so called “immunity debt” is neither grounded on current best evidence nor compatible with our understanding of immunity 👇

Colin Furness MISt PhD MPH

@FurnessColin

2 years

A word on the idiocy known as "immunity debt". How did such a nonsensical idea take hold? Simple. The obvious mental model for our immune system is a muscle: use it or lose it. Muscles atrophy when we don't use them. The same mental model works for our memories & skills. 1/19

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

NO, worst case scenario is really what it is: THE WORST. Very disturbing message of apparent reassurance that liver transplant is fine compared to the alternative of putting ALL our efforts in understanding & prevent..the WORST case scenario. For goodness sake & our children’s!

Dr. Robert

@Robert83563198

2 years

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 years

For teachers and curriculum developers: A useful set of core competencies in Evidence-Based Practice for Health Professionals #EBM #EBCP

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

7 months

@julienbahloul Grotesque et indécent.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

En France 🇫🇷 prescription du #paxlovid sur simple ordonnance. En Suisse 🇨🇭… 😶😶😶

Le Paxlovid sera désormais délivré sur simple ordonnance

L’objectif est de faciliter l’accès à pilule contre le covid mise au point par Pfizer

www.20minutes.fr

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

A nouveau un mauvais message. Le booster est présenté comme un caprice personnel - une frivolité permettant un voyage en somme - plutôt que par son attribut principal: la diminution du risque individuel. Aberrant et en discordance avec les données. Mais enfin… 😣

BAG – OFSP – UFSP

@BAG_OFSP_UFSP

2 years

Pour voyager cet été, les personnes qui le souhaitent pourront recevoir une vaccination de rappel Covid-19 supplémentaire. Les coûts seront à leur charge. Une proposition est en consultation jusqu'au 1er juin. #CoronaInfoCH

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Série d’articles aussi cocasses qu’absurde. La 4e dose est déjà utile, pour soi & la collectivité, et pas seulement « pour voyager » ⁦ @economie_suisse ⁩ n’a strictement rien a dire en matière de santé. Aucune autorité, compétence ou légitimité.

Vaccination Covid: Une 4e dose pour voyager: «Ce n’est pas à la collectivité de payer»

L’OFSP a proposé de permettre à celles et ceux qui en ont besoin de recevoir un deuxième booster, mais à leur charge. Les avis récoltés sont très divisés.

www.20min.ch

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Such an honor and pleasure to spend time with @GuyattGH visiting us in #geneva 🇨🇭 @Hopitaux_unige ! And the Spring weather is with us ☀️😎

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

🚨Our updated @WHO #LivingGuidance on #COVID19 now adding recommandation on #ivermectin to previous recs on #steroids #remdesivir #lopinavir #Hydroxychloroquine 👉 👉 #MichaelJacobs @Bram_Rochwerg @PerVandvik @diazjv @bmj_latest

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

@WHO_Europe please help our Swiss authorities 🙏

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 years

Explore our New #RapidRecs on #ProstateCancer PSA #screening @bmj_latest with infographics, evidence summaries & decision aids @KariTikkinen @EBMUrology @will_s_t @drhelmac @PerVandvik @RSiemieniuk @lyubovlytvyn @MAGICapp @GRADE_WG @UNIGEnews

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

@ParmelinG @OCDE_fr Honte de vos propos, dans le fond et la forme. Indigne d’un conseiller fédéral de juxtaposer ainsi nos si nombreuses victimes à notre économie. Nous vous invitons fortement à reformuler vos propos avec la sensibilité que votre fonction requiert.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Italian study shows ventilation can cut school COVID cases by 82% | Reuters

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Same illusion worldwide unfortunately. Including in #Switzerland 🇨🇭 As if we got used to big numbers, and got even better at minimizing actual events, maximizing unreasonable hopes, while we built neither more health capacity nor sufficient economic and social support for all.

Eric Topol

@EricTopol

4 years

The illusion that things have gotten much better when they're still worse than the first 9 months of the pandemic. Not a time to let up. @nytgraphics @COVID19Tracking

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Un mélange de tant de confusions, contre-vérités dans les réponses de Mme Amarelle, en particulier sur le caractère inopportun des mesures en phase ascendante de l’épidémie. On reste sans voix quant à l’incapacité de nos cantons d’arriver à des mesures coordonnées et efficaces.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Confirmed higher estimates transmissibility by +50-70% for 501Y & B.1.1.7 in #Switzerland 🇨🇭 leading in #Geneva . This means the current strong measures barely contain hospitalizations & circulation continues. Not a time to let go of them, unless one is looking for a high 3rd wave.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

As many continue to minimize #COVID19 impact, one needs to remember: Thousands of US Youths Cope With the Trauma of Losing Parents to COVID19 via @JAMA_current part of @JAMANetwork

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Le délai d’accès au #Paxlovid ( #nirmaltrevir /ritonavir) en #Suisse 🇨🇭 est tout simplement incompréhensible et injustifiable. Qu’avons nous appris de tout ceci?

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

These updated criteria in #Switzerland are very risky ⚠️⛔️ We keep deluding ourselves we can negotiate with reality (at the expenses of our unlucky fellow citizens).

Marc Brupbacher

@MarcBrup

4 years

Der Bundesrat setzt die Richtwerte für mögliche Verschärfungen immer weiter hoch. 14-Tages-Inzidenz ist neu 450 statt 350 (wenn alle Risikogruppen geimpft sind sogar 600). Hospitalisierungen im 7-Tages-Schnitt neu 120 statt 80.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

#EricMasserey , médecin cantonal adjoint, aurait affirmé que « La classe n’est pas un lieu où le risque de contamination est élevé». ⚠️ C’est faux. Ces déclarations sont basées sur des données obsolètes, le variant delta ayant changé l’épidémiologie 🦠

Vaud - Les écoles parient sur trois semaines de port du masque

A l’aube d’une deuxième rentrée marquée par la pandémie, les cas positifs sont plus élevés que l’an passé. Mais le Canton est serein, et aspire à un retour sur les bancs «normal».

www.20min.ch

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

On assiste à une véritable propagande de normalisation précoce. Est ce un syndrome collectif ou un agenda politique?

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Est-il permis d’être alarmiste? 🦠🌊 De dire que nous sommes extrêmement inquiets, que les hôpitaux se remplissent dangereusement ? Ou bien faut il feindre d’avoir tourné la page vers la “normalité” & ménager chacun avec réassurance en se félicitant de taux vaccinaux médiocres?

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

You are starting a medical career and wonder what specialty to focus on? Learn to take care of #LongCovid , there will be plenty of work for you, and we’ll need you.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

@samiahurst Weekend difficile. Malgré le socle anticipé, nous devons chercher des lits pour les nouveaux malades, une unité ouverte vendredi déjà presque pleine, d’autres ouvertures prévues en début de semaines. Les clinique s’y mettent pour nous aider. La vague est déjà là, malgré les dénis

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Well, Switzerland has definitely proven that it values risk differently than others, doesn’t it? We think a lot of ourselves if we persist in thinking that this is a sign of collective wisdom…

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 months

Very honored and excited to attend this presentation by Prof Ziyad Al-Aly on « #LongCOVID : the lasting legacy of the pandemic ». A critical reality with unique challenges @zalaly @mayssamnehme @iguessous @hug_ge @unige_en #postcovid #covid19

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

As usual now, New Zealand is showing the way ahead with #COVID19 and #vaccination . Instead of being fascinated by our morbid views on so-called freedom (ours is not btw), fascination against health authorities, they just get the message simple and right: “Do it for each other”.

Dr Zoë Hyde

@DrZoeHyde

3 years

New Zealand's new #COVID19 vaccination campaign. "Do it for each other."

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Joyeux Noel a toutes et tous, et en particulier à nos équipes medico-soignantes qui travaillent sans relâche auprès de nos patients 📈🦠 @Hopitaux_unige Soyez prudents 🙏✨

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Edward Mills shares early results from #TOGETHERtrial on #Ivermectin (no surprise) & #Fluvoxamine (intriguing ↘️ in hospitalisations) 🚨 major inhibitor of CYP1A2 & 2C19 -> numerous interactions ⛔️mechanism of action might not apply to other SSRIs 👀👇

August 6, 2021: Early Treatment of COVID-19 with Repurposed Therapies: The TOGETHER Adaptive...

Speaker Edward Mills, PhD, FRCP Professor Department of Health Research Methods, Evidence & Impact McMaster University, Canada Topic Early Treatment of COVID-19 with...

rethinkingclinicaltrials.org

NIH Pragmatic Trials Collaboratory

@Collaboratory1

3 years

📣 Starting now in #COVID19 Grand Rounds! "The TOGETHER Early Treatment of COVID Trial: Building Platform Trial Infrastructure for Infectious Diseases" with Dr. Edward Mills of @HEI_mcmaster . 🔗 #pctGR

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Still no access to vaccine for patients exposed to monkeypox in #Switzerland … we failed to get access today once again. We have to send them to France… @BAG_OFSP_UFSP @EckerleIsabella @FLAHAULT

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

#HappyNewYear to all 💫 Let us Hope with reason, and act wisely, for better times ahead 🙏

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

« Viral infections tend to create disorder in a person’s immune system, making it easier for a secondary bacterial infection to take hold and intensify its effects in some cases. » Not quite an immunity debt. But direct harm from exposure.

Irene Tosetti, MD MBA MPH

@itosettiMD_MBA

2 years

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

5 years

Our newest #RapidRec is out in the @bmj_latest ! With guidance, and #evidence #infographics on #Gastrointestinal #bleeding #prophylaxis for critically ill patients: 👉The #RapidRec : 👉Its Systematic Review & Network Meta-analysis

The BMJ

@bmj_latest

5 years

What is the role of gastrointestinal bleeding prophylaxis in critically ill patients? This #RapidRec guideline looks at new evidence Includes a #BMJInfographic showing an overview of the benefits and harms @will_s_t

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

7 years

Among >9400 recommendations for clinical practice in @UpToDate , we found that 1/3 were strong rec while 2/3 were weak rec. See our new study on adherence to #GRADE criteria for strong rec: @Hopitaux_unige @McMasterU @GRADE_WG @grade_planet @GRADE_McMaster

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

“On ne pensait pas… … que les coûts de la santé 📈 🚨⚕️ …qu’une nouvelle vague 🌊 …que l’énergie 🪫 … que l’intolérance 🤬 …que l’extrémisme et le fascisme 🚷 … qu’une guerre en Europe ⚔️ …que le climat 🌍⛔️ » Et si on y pensait alors..?

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

Nous faisons tout ce que nous pouvons @Hopitaux_unige mais situation est déjà difficile. De nombreux cas sévères.Tous les systèmes ont une limite & personne ne voudrait la vivre 🙏protégez vous & vos proches, & minimisez la propagation du 🦠 @EckerleIsabella @FLAHAULT @samiahurst

HUG

@hug_ge

4 years

Au 27 octobre à 12h, 359 malades Covid actif, dont 43 aux soins intensifs et intermédiaires, sont hospitalisés aux HUG. Suivez l'évolution de la situation aux HUG sur #Covid19 #CoronaInfoCH #coronavirus #HUGcovid19

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

No kidding… #FakeMildness Hospitalisation for COVID-19 linked to greater risk of later readmission or death | LSHTM

Hospitalisation for COVID-19 linked to greater risk of later readmission or death | LSHTM

People who had been hospitalised for COVID-19 in 2020 - and survived for at least one week after discharge - were more than twice as likely to die or be readmitted to the hospital in the next several...

www.lshtm.ac.uk

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Intimidations, accusations, diffamations, comme souvent en toute impunité👇 Twitter est un espace publique, donc soumis au cadre légal. Nous y veillerons également. Merci à chacun.e de signaler de telles actes, pour que nous puissions garder un espace respectueux d’échange.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

🚨Our newest #RapidRec in @bmj_latest is out! Non-inhaled medical #Cannabis for people with #ChronicPain : "If standard care is not sufficient, we suggest offering a trial of non-inhaled medical cannabis to people with chronic pain" 👉 @JasonWBusse @DenaZera

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

Lorsque une maladie se comporte différemment que prévu, le principe de précaution devrait prévaloir, jusqu’à avoir une meilleure compréhension. L’obsession de réassurance ne doit pas dominer nos décisions,pas plus que la panique. Il faut retrousser ses manches, en effet. Prudence

Antoine FLAHAULT

@FLAHAULT

2 years

1/6 - #VarioleDuSinge : 316 cas confirmés, toujours pas de décès: N’en fait-on pas un peu trop? A-t-on perdu la raison avec la pandémie de #COVID19 ? Ne voit-on pas des pandémies partout désormais? Je vais tenter d’expliquer pourquoi je pense que la réponse est 3 fois négative.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 years

Explore our New BMJ #RapidRecs on #Oxygen therapy for acutely ill medical patients @bmj_latest - - with #infographics and evidence summaries in @theMAGICapp @RSiemieniuk @PerVandvik @will_s_t @lyubovlytvyn @dkchu @AlhazzaniW @Hopitaux_unige @UNIGEnews

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Enfin un bon article sur les risques dans les écoles @LeTemps 👇 L’épidémiologie & le risque pour les enfants ont changés avec delta et nos configurations. Le discours de nos autorités reste dispersé et très peu convainquant pour protéger les enfants & leur scolarité @FLAHAULT

Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Variant Delta à l'école: quels risques pour les enfants?

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

10 months

@MaudBregeon Un vote honteux. Politiquement et humainement inexcusable.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Omicron will become dominant variant in London in next 48 hours, UK health secretary says The UK has confirmed its first death from the Omicron coronavirus variant, Prime Minister Boris Johnson said Monday.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Greece: Suspension of unvaccinated workers begins

Suspension of unvaccinated workers begins | eKathimerini.com

Thousands of suspensions began as of Wednesday of workers in public health units who had not been vaccinated against Covid-19 within the deadline set by the government.

www.ekathimerini.com

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

5 months

@BFMTV Ça en dit long sur celui qui s’en navre et s’en désole, avant tout…

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Cowardice & hypocrisy. Enough with these dangerous statements.

Tʜᴏʀsᴛᴇɴ Kᴜʀᴢ

@t_kurz

3 years

“In the situation we are in now, measures would be neither politically nor socially acceptable.” “If it comes to situations like we have seen in Bergamo, then we may again discuss measures that can rapidly achieve their effect.” — Patrick Mathys ( @BAG_OFSP_UFSP ), PdP 17.08.2021

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

5 months

@Captbobdad @RyanRozbiani There is, but that's not what it is.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

Les journalistes spécialisés dans la couverture des sujets de santé devraient sans doute avoir un master en santé publique (ou équivalent). Ou alors gagner en humilité. Leurs erreurs, affirmations, exagérations ou minimisations - hélas fréquentes - peuvent être dangereuses.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

10 months

@OrenZiv_ Oh is that so…. They didn’t mean it? Nor did they mean the indiscriminate bombing? One is responsible for its acts and words, for better or worse.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

A quel point la #Suisse est-elle en retard sur la troisième dose de #vaccin Covid ? @heidi_news @ypandele Un retard effroyable et injustifiable, dont nous paierons le prix, avec l’accroissement vertigineux d’Omicron, au pic de notre vague delta.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

6 months

@Le_CRIF Totalement en désaccord. Très étrange positionnement. Vous devriez au contraire souhaiter un état partenaire de paix, de plein droit et pleinement reconnu.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

@EckerleIsabella It’s completely implausible indeed. But coping mechanisms using minimisation and normalization have become highly prevalent… they’ve been circulating for years 🫤

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

🚨 Situation TRÈS tendue, en augmentation 📈 Il est temps d’agir: mesures++, prudence++ et vaccination++(premiere, deuxième booster). Votre système de santé doit être préservé pour vous servir toutes et tous au mieux 🙏🙏🙏

HUG

@hug_ge

3 years

Au 9 décembre à 7h, 174 malades Covid+ et suivis après Covid sont hospitalisés aux HUG. Suivez l'évolution de la situation sur #CoronaInfoCH #Covid19 #covid #gen ève

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

7 months

@extrsh @muhammadshehad2 What’s your evidence for those claims that these are guilty of these crimes? I suspect none, and yet you elaborate your argument as if you knew. Treating them like this is illegal and can find no justification. So don’t try any. Israel’s army is expected to have higher standards.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

4 years

A nice clinical review on "Severe covid-19 pneumonia: pathogenesis and clinical management" @bmj_latest

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

3 years

@Gab_H_R Throughout the waves, the majority of deaths do not occur in the ICU, but in acute wards, nursing homes, and at home. This is why the sole focus on ICU beds has always been misleading, and even more so now with Omicron.

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Thomas Agoritsas, MD PhD

@ThomasAgoritsas

2 years

@LaurentAFKaiser Quite right. Critical to act now. A serious prevention campaign, access to vaccine and treatment, testing, isolating… all things that work.

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