Medical experts including
@drsanjaygupta
from
@cnn
are focusing on the treatment of monkeypox with patients who are willing to share their stories. You can see Dr. Gupta’s story here: .
SIGA announces approx $13M of procurement orders for oral TPOXX, including $11M for initial procurement from two new international jurisdictions & approximate $2M from a country in the Asia Pacific region, in response to monkeypox outbreak. To learn more:
The UK has approved SIGA’s oral tecovirimat (TPOXX) for the treatment of smallpox, monkeypox, cowpox, and vaccinia complications following vaccination against smallpox in adults and children with a body weight of at least 13kg. For more please visit:
Findings published in the
@TheLancetInfDis
on treatment of monkeypox patients in the UK: Patient treated with tecovirimat experienced no adverse effects. TPOXX (Tecovirimat) is approved in the US for smallpox and in the European Union for smallpox/monkeypox/cowpox and
As smallpox immunity wanes, SIGA technologies addresses the issue of orthopox virus antivirals and treatments with our proposed solution, TPOXX. To learn more watch:
The
@CDCgov
has provided guidance for Tecovirimat use under expanded investigational new drug protocol for monkeypox treatment. For more information visit:
With monkeypox cases rising & interest in access to treatment increasing, we’ve received questions about how TPOXX was approved by regulatory agencies in Europe, UK & US.
@NJEM
video summarizes 2018 data supporting the approvals in Europe and the UK.
Please join us tomorrow at 12pm EST for A.G.P.’s Monkeypox panel. SIGA will be presenting alongside Emergent Biosolutions & TONIX Pharmaceuticals to discuss the recent outbreaks of monkeypox in the U.K., EU, & U.S. For more information & to register:
In an era marked by significant advances in biological sciences, there are also concerns about the development of biological weapons. This
@BelferCenter
article outlines current U.S government processes to bolster
#biosecurity
measures. See here:
“Somebody would reconstruct, say, a smallpox virus and have that spread, and that would not only kill millions, it could potentially kill billions” – Bill Gates on bioterrorism, 2017, PBS
SIGA is pleased to announce it has received
@US_FDA
approval for the intravenous (IV) formulation of TPOXX for the treatment of smallpox. This provides an important option for those unable to take the oral formulation of the drug. Full details here:
Ben Novak, SIGA’s Director of Business Development, will present Wed at 8:30 AM CET at NCT Europe 2022; ‘Medical Preparedness for CBRNe Events’ covers the importance of availability of treatments in the face of potential threats. More from
@IBConsultancy
:
@SIGA
is excited to announce a collaboration with
@KaliVir
to make TPOXX available to support future clinical programs of KaliVir’s oncolytic vaccinia immunotherapy platform. For more information:
What is happening in Africa will definitely impact what is happening in the West and vice versa.” Says Yap Boum, an epidemiologist in Cameroon who works with Doctors Without Borders. To learn more about monkeypox and its impacts see
@ScienceMagazine
:
In a study published on
@NatureMicrobiol
, in vitro analysis of the virus isolate of the first human monkeypox case in France shows that TPOXX (tecovirimat) is effective against the virus at nanomolar concentrations. To read the full study please visit:
SIGA announced today the international procurement of roughly $16 million for oral TPOXX®, including approx. $10m from the European Commission and approx. $6m from two countries in the APAC region. For more details, see here:
“We were developing a drug for a disease that doesn’t exist. It took a long time to figure out,” Dennis Hruby says as he speaks about SIGA’s story to the Wall Street Journal. To read the full article visit:
Today, we announced that the U.S. Department of Health and Human Services has exercised a procurement option for the delivery of approximately $113 million of oral TPOXX® treatment courses. See here:
Congrats to our CEO Phil Gomez for being named as one of the Top 25 Healthcare Technology Leaders of Washington, DC for 2023! We are proud of the work Dr. Gomez has done to help provide solutions for unmet needs in the
#healthsecurity
market. Learn more:
The
@WHO
has declared
#mpox
a
#publichealth
emergency of international concern (
#PHEIC
), triggered by a major outbreak of the viral infection in the DRC and its expansion to nearby countries.
@DrTedros
"Today, the Emergency Committee met and advised me that in its view, the situation constitutes a public health emergency of international concern. I have accepted that advice"-
@DrTedros
#mpox
Listen to our Executive Vice President and Chief Medical Officer,
@DrJayVarma
, discuss the initial results from the PALM 007 clinical trial in this video:
SIGA is pleased to announce that it has received approval from Health Canada for oral TPOXX as an extraordinary use new drug. This is a key milestone for SIGA’s partnership with
@NationalDefence
and will allow SIGA to continue to supply oral TPOXX to the DND and
@GovCanHealth
.
In this
@GoHealio
article,
#publichealth
experts including our EVP and CMO,
@DrJayVarma
, share insights on preparedness for the next pandemic as part of the “Life during COVID” series. See here:
We are honored to be recognized as one of
@Forbes
2023 America’s Best Small Companies. This recognition is a tribute to our team and the impact we have made in providing solutions for unmet needs in the
#healthsecurity
market. To learn more, visit:
Today we announced a new contract with the
@DeptofDefense
for the procurement of approximately $9 million of our antiviral drug, representing the third procurement contract award from the DOD in the past three years. See our press release:
Throughout the monkeypox outbreak
@SIGA
has received TPOXX orders from more than 13 entities across the world including the U.S. To learn more about the most recent $10.7M order from the U.S. Department of Defense please visit:
#Smallpox
and other orthopoxviruses pose significant threats to the world and are capable of deliberate weaponization, accidental release, & exploitation of vulnerable populations. Read more in the
@BioCommission
’s recent report:
#BoxthePox
Earlier this month, our EVP and CMO,
@DrJayVarma
provided his insights about pandemic preparedness and
#biodefense
policies at the
@BioCommission
meeting. View Dr. Varma's testimony:
Our Executive Vice President and Chief Scientific Officer Dr. Dennis Hruby participated in a Q&A with
@ClinicalLeader1
to discuss our focus on medical countermeasures for
#CBRN
threats and emerging
#infectiousdiseases
. Read the full article:
A recent study conducted by
@LancetGH
describes the main epidemiological features of the
#mpox
outbreak, presents new and evolving features of this
#infectiousdisease
, and highlights differences in regional trends. See here:
As cases are increasing in other countries,
#mpox
requires continued surveillance, therapeutics and mitigating strategies.
@GlobalVirusNews
developed an article highlighting the prevention & treatment of mpox and the need for pandemic preparedness:
Recently the White House administration launched the Global Health Security Strategy to prevent, detect, and respond to the spread of
#infectiousdiseases
in the U.S. and around the world. Learn more about the strategy in this
@CSIS
video:
We are honored to be named on
@Deloitte
Technology’s Fast 500 list, recognizing the most innovative and fastest-growing companies across North America. We thank our team & partners for their support in helping us become an industry leader across the
#lifesciences
sectors.
At the World Economic Forum’s annual meeting in Switzerland, the
@WHO
emphasized the need to prepare for Disease X, an unknown pathogen that could emerge in the future and cause a pandemic. Read more:
SIGA is pleased to collaborate with Bioarchitech, an innovator of next-gen cancer immunotherapies. The pre-clinical studies will investigate TPOXX in combination with Bioarchitech’s proprietary vaccinia-based immunotherapy platform to see if TPOXX can enable delivery of larger
#ICYMI
as part of
@AuthorityMgzine
’s interview series, our EVP and CMO
@DrJayVarma
explored the impact the COVID-19 pandemic had on the American
#healthcare
system and shared five key areas in need of improvement. Read the full interview:
#Mpox
cases have been on the rise since October, prompting efforts to prevent a summer surge like what was seen in 2022. In
@thehill
, our EVP and CMO
@DrJayVarma
shares his perspective on the increase of cases this year & the mpox outbreak in the DRC.
We are excited to share that our CEO Diem Nguyen, Ph.D., M.B.A., is featured in the latest issue of the Darden Report magazine. As a proud alumna of
@DardenMBA
, Diem shares lessons on leading a team and cultivating the values essential for success:
We are pleased to announce the appointment of Diem Nguyen, Ph.D., as our new CEO. We look forward to Dr. Nguyen’s leadership as we continue to develop antiviral therapies for
#infectiousdiseases
. See the full press release:
Today we announced the signature by the European Commission’s DG HERA of a joint procurement framework contract under which 13 participating countries from the EU and EFTA can enhance
#smallpox
preparedness. See details in our press release:
Recently
@CEPIvaccines
and
@IQVIA
have announced a strategic collaboration to enhance the world’s preparedness to rapidly conduct clinical research for biological countermeasures against emerging
#infectiousdiseases
. Learn more:
Tomorrow at 10:45am ET, our EVP and CMO
@DrJayVarma
will join Former
@NIAIDNews
Director Anthony Fauci, MD, and the CEO of
@nyphospital
Steve Corwin, MD, for a panel discussion during New York-Presbyterian’s professional development retreat to discuss health leadership.
Placebo-controlled clinical trials were initiated in 3 countries including the United States, United Kingdom and Democratic Republic of Congo to assess the safety and efficacy of TPOXX in participants with monkeypox. To read more please visit:
Existing harm reduction measures, at home-testing, and advancements in vaccines and treatments can help keep the monkeypox (
#mpox
) numbers as low as possible. However, we are not out of the woods just yet. Read the full article:
#ICYMI
in this
@GoHealio
“Life during COVID” series, industry leaders including our EVP and CMO,
@DrJayVarma
, share insights on the country’s preparedness for the next pandemic. See here:
On
#NationalAdministrativeProfessionalsDay
, we would like to recognize all of our administrative professionals at SIGA. They are the backbone of the company and keep us moving and thriving every day. Thank you for your continued hard work and dedication!
SIGA has received approval from
@EMA_News
for oral tecovirimat, the same SIGA formulation approved by the
@US_FDA
under the brand name TPOXX, for treatment of several orthopox viruses. This enables maximum access to tecovirimat across Europe, a key milestone for SIGA.
SIGA today announced the declaration of a special dividend of $0.45 per share on the common stock of the Company. To join our earnings call, please visit our events page for details.
Last month marked the 4-year anniversary of
@WHO
declaring
#COVID19
a global pandemic. Our EVP and CMO
@DrJayVarma
joined
@fox5ny
’s
@thisiscwelch
to discuss where we are now and where we are headed. Watch the full clip:
As exemplified by the
#COVID19
and
#mpox
pandemics, major
#infectiousdiseases
and
#epidemics
have devastating impacts amongst individuals from minority ethnic groups, poorer socioeconomic backgrounds, and urban and rurally deprived locations.
#DYK
that
#smallpox
was responsible for 300 million deaths in the 20th century alone? Though smallpox has been eradicated, there is concern that it could be used against us. Learn how we are helping improve the preparedness for a potential smallpox event:
The
@CGDev
recently launched Season 2 of their Pandemic Proof podcast. In this episode, host
@JavierHGuzmanC
is joined by
@JeanKaseya2
, Director General of
@AfricaCDC
, to discuss progress in enhancing outbreak preparedness and response in Africa. Tune in:
As
#mpox
spreads rapidly,
@Nature
spoke with
#infectiousdisease
specialists to explore how this current emergency compares to the global outbreak of 2022 and how the clade Ib strain differs from the clade II strain that caused the earlier outbreak.
Today
@NIAIDNews
announced topline results from a preliminary analysis of the PALM 007 clinical trial evaluating our investigational drug for the potential treatment of
#mpox
in the Democratic Republic of the Congo. See our press release:
The
#EPOXI
trial has successfully launched its first sites in Germany and Belgium. This randomized controlled trial, led by UMCU and
@Ecraid
, will assess the efficacy and safety of our antiviral drug to treat adult
#mpox
patients.
Following
@WHO
’s
#PHEIC
declaration,
@pharmaphorum
spoke with our EVP and CMO
@DrJayVarma
about the clade 1b
#mpox
strain, available vaccines & treatments, the initial results from the PALM 007 study, and the criticality of pandemic preparedness. See here:
The Democratic Republic of Congo is currently experiencing the highest annual number of suspected
#mpox
cases reported. According to
@WHO
, the consequences could potentially be more severe than the worldwide outbreak last year. Learn more:
The
@WHO
recently released a new
#publichealth
taxonomy for social listening on respiratory pathogens alongside other useful tools for infodemic management. Learn how this new tool can help WHO inform and guide their infodemic response:
Today kicks off
@BARDA
’s Industry Day! We look forward to collaborating with BARDA and other companies within the
#healthsecurity
space to discuss how we can better prepare for and respond to
#publichealth
emergencies in our ever-changing and unpredictable world.
#BID2023
The
@CDCgov
has released interim clinical considerations to help with decision-making in the management of severe manifestations of monkeypox (
#mpox
). Learn more:
As we continue to focus on providing solutions for unmet needs in the
#healthsecurity
market, we have cultivated key relationships with
@BARDA
and other organizations to enhance U.S national health preparedness against a potential threat. Learn more:
We are excited that SIGA was featured in the January 2021 issue of NCT Magazine. This profile highlights SIGA as a leader in the health security market and our mission to address urgent recognized threats, such as bioterrorism:
#SIGA
#CBRN
#NCT
SIGA is excited to announce that Dr. Doug Grosenbach, Senior Director Poxvirus Research, will be presenting today at the
@Intel_Sec
CBRNe Summit Europe 2021 in Brno, Czech Republic on Smallpox Preparedness: Integrating TPOXX® into Response Planning.
Recently
@WHO
launched a global Strategic Preparedness and Response Plan to stop outbreaks of human-to-human transmission of
#mpox
through coordinated global, regional, and national efforts. See here:
From insightful discussions to forging new connections,
#NCTEurope2023
was an enriching experience. We had the opportunity to connect with
#CBRN
professionals & share our focus to provide solutions within the
#healthsecurity
market. Learn more about SIGA:
Recently
@WHO
released a technical brief providing key findings from a survey that provide valuable insights into the experiences and needs of communities affected by
#mpox
.
While smallpox has been eradicated worldwide, the bio-threat for a future outbreak continues to exist. That’s why SIGA is working with governments worldwide to ensure we’re properly prepared for the worst with safe and efficacious treatments.
Siga CEO Phil Gomez will be speaking today at the NCT USA Conference, discussing the importance of advancing antiviral drug capabilities in preparation for any potential future endemic outbreaks.
Our goal is to provide solutions for unmet needs in the
#healthsecurity
market that comprises medical countermeasures against
#CBRN
threats, as well as emerging
#infectiousdiseases
. Learn about our current efforts to enhance
#pandemic
preparedness:
Let’s work together to promote
#healthsecurity
and increase health preparedness. We are seeking an experienced Director, Formulations & Process Development to join our Chemistry, Manufacturing and Controls team in Corvallis, Oregon. Learn more:
In this
@ProSyn
article, Jose Manuel Barroso, former president of the European Commission and Chair of the Board of
@gavi
shares ways to improve upon the innovative mechanisms that emerged from the COVID-19 pandemic. Read the article:
Congratulations to
@dr_demetre
, Director, CDC Division of HIV Prevention, and Deputy Coordinator, White House National Mpox Response, for being honored on
@statnews
’ 2023
#STATUSList
! Learn about his work to mitigate the
#mpox
outbreak:
SIGA announced that the Public Health Agency of Canada has awarded a contract to our partner, Meridian Medical Technologies, for the purchase of up to approximately $33 million of oral TPOXX within five years.
As we celebrate
#PrideMonth
, we are dedicated to taking proactive steps to prevent and stop
#mpox
outbreaks, leveraging our expertise in
#infectiousdiseases
to make a difference in the lives of individuals worldwide. Learn more:
#PRIDE2024
If you are attending events such as
#NYCPride
or other
#PRIDE2024
celebrations – have fun, remain vigilant, & prioritize safety measures to protect yourself and those around you from
#mpox
. Learn more from the
@CDCgov
:
Today we join
@WHO
in recognizing
#WorldHealthDay
and championing the right of everyone, everywhere to have access to quality health services, education, and information. Learn more:
Recently
@WHO
released a toolkit to aid country-level risk communication engagement practitioners, decision-makers, and partners in planning and implementing readiness and response activities for
#mpox
. See here:
In an interview with
@BBCNews
,
@BillGates
said that
#bioterrorism
is the future threat we aren’t thinking enough about. Learn more about the importance of preparing against biological threats and the risks they pose to the public:
Last month the
@UN
held an interactive multistakeholder hearing, supported by
@WHO
and
@UHC2030
, to gather input on the dimensions of pandemic preparedness, prevention, and response.
Read the full overview here:
Staying safe from health risks including
#mpox
remains crucial and we continue to emphasize the importance of prioritizing
#publichealth
and wellbeing. Learn more about mpox prevention, symptoms, and resources: