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R3i Foundation

@R3i_Foundation

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The R3i is a worldwide, non-profit foundation recognizing the complications in patients with atherogenic dyslipidemia. 🌐

https://t.co/0r67R9Wvxx
Joined February 2016
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
29 days
It is with great sadness that the R3i Foundation announces the passing of Professor Jean-Charles Fruchart. Jean-Charles was a titan in lipid research, whose contributions have shaped much of our current understanding of lipoprotein metabolism and cardiovascular risk management.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
R3i es una organización mundial sin fines de lucro que tiene el objetivo de abordar eficazmente el riesgo excesivamente elevado de complicaciones macro y microvasculares en pacientes con dislipidemia aterogénica. Para información en español visite ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
This free booklet provides a critical background to triglyceride-rich lipoproteins and their role in ASCVD. Available in English, Spanish and Japanese! Subscribe for free and download it now ➡️ #R3i #ASCVD #dyslipidemia
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
The R3i is a multidisciplinary non-profit organization that aims to successfully address the excessively high risk of macro- and micro-vascular complications in patients with atherogenic dyslipidemia. Visit for more information. #R3i #ResidualRisk
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
This Free Booklet provides a critical background to triglyceride-rich lipoproteins and their role in ASCVD. Follow this link to subscribe for free and download the booklet now ➡️ #R3i #residualrisk #residualriskreduction #triglyceride #ASCVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
Este folleto gratuito brinda información previa crítica sobre las lipoproteínas ricas en triglicéridos y su función en la ASCVD. Disponible en español, inglés y japonés. Regístrese gratis al sitio web de R3i y descargue el folleto ➡️ #R3i #ASCVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
Availble in English, Spanish and Japanese, this booklet/slidedeck, the second in the series, focuses on evidence from clinical trials with PCSK9-targeted therapeutics. Subscribe to the R3i website and download this free booklet now ➡️ #R3i #ResidualRisk
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Genetic variations at the LPA locus are associated with CHD events during statin therapy. This provides support for exploring strategies targeting circulating concentrations of Lp(a) to reduce CHD events in patients receiving statins. Read full article➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
We´d like to thank all who attended our meeting in Marrakech where we discussed how to reduce vascular complications of T2D among other important topics. We will soon post videos of the meeting. Stay tuned! ➡️ #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Meet Prof. Raul D. Santos @rauldsf_santos Raul D. Santos, MD, MSC, PhD, is President of the International Atherosclerosis Society and Director of the Lipid Clinic of the Heart Institute (InCor) of the University of São Paulo, Brazil. Learn more➡️ #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Atherosclerosis (AS) is a progressive and deadly disease affecting the coronary, cerebral & peripheral circulation. Learn about the six stages of atherosclerosis development ➡️ (slides 5 & 6).
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Atherosclerosis begins with damage to the endothelium. Common causes include: - High cholesterol - High blood pressure - Inflammation, like from arthritis. - Obesity or diabetes - Smoking That damage causes plaque to build up along the walls of your arteries. #CardioTwitter
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
During pregnancy, a woman's #cholesterol levels rise. Post-pregnancy, cholesterol levels should return to normal. But after menopause, women’s #LDL cholesterol levels go up, while protective #HDL levels decline. By age 75, women tend to have higher cholesterol levels than men.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
PPARα activation regulates lipid metabolism by controlling the expression of PPARα target genes: 👇 Learn more (slide 6):
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
#MedicalResearch | Lipoprotein(a) and Residual Cardiovascular Risk: ✅Lp(a) is a potential contributor to residual cardiovascular risk ✅Genetics variants in LPA gene are associated with Coronary Heart Disease ➡️The complete study here: #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Gestational diabetes occurs when the pancreas can't keep up with producing enough extra insulin to overcome the upgraded resistance in the cells derived by the hormones produced by the placenta during pregnancy. #Diabetes #GestationalDiabetes #R3i #ResidualRisk
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
📈CVD is a leading cause of death in Europe and Worldwide: ✔️CVD accounts for 45% of all deaths in Europe and 31% of all global deaths. Most of these are due to ischemic heart disease. Find out more (slide 5):
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
The DASH dietary pattern is a treatment approach recommended in reducing vascular residual risk. The DASH dietary plan emphasizes consuming 🟢Fruits, vegetables, whole grains, nuts & fish 🔴 Restricting Red meat, sweets & sugary drinks ➡️ (slide 9) #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Atherogenic dyslipidemia is defined as an imbalance between proatherogenic ApoB-containing Lps & antiatherogenic ApoA-I-containing Lps contributing to the development of AS. The impact of dyslipidemia on the progression of AS is shown here ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
The #R3i team wishes all medical community and followers a healthy, successful and prosperous 2023! 🌟 #NewYear #HappyNewYear #2023
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In patients with a history of ischemic stroke, a recent study showed that elevated fasting remnant cholesterol levels increased the risk of atherosclerosis progression (as assessed by common carotid artery intima-media thickness). Learn more ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Meet our President, Prof. Jean-Charles Fruchart. He is currently a professor at Pasteur Institute of Lille and is the author of more than 700 scientific papers in the most prestigious international journals. Meet all our members at➡️ #R3i #residualrisk
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
HDL is essential to the ‘reverse cholesterol transport' pathway, which promotes the transfer of excess cholesterol from extra-hepatic tissues to the liver for excretion. CV risk ⬇️ by 2% in men & 3% in women for every 1 mg/dL increase in HDL-C ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
This concept has been a catalyst for the development of a novel SPPARMα agent, pemafibrate, which acts at multiple targets relevant to vascular risk. Will pemafibrate be the key to reducing residual cardiovascular risk? Read the abstract here ➡️ #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
Did you know 🤔 up to 50% of CVD can be reduced by regular physical exercise 🏃‍♂‍ in patients with type 2 diabetes. Explore the lifestyle modifications that are a necessary first step in reducing vascular risk ➡️ #R3i #insulinresistance #diabetes
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
According to a meta-analysis conducted by the Cholesterol Treatment Trialists Collaboration (CTTC), lowering LDL-C by 1 mmol/L reduces major vascular events by 21% and all-cause mortality by 12%. Examine the results ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In part, this was because clinical studies with the fibrates, PPARα agonists, did not conclusively show that targeting this dyslipidemia, against a background of statin treatment, reduces cardiovascular events. Some also had safety issues. Learn more ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Why are LDL cholesterol, HDL cholesterol and triglycerides the basic measurements needed to evaluate a patient? Henry Ginsberg explains in this short video. Watch now ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Cholesterol plaques can be the cause of heart disease. Plaques begin in artery walls and grow over years. Their growth slowly blocks blood flow in arteries. A cholesterol plaque can rupture. The sudden blood clot that forms over the rupture then causes a heart attack or stroke.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
Matrix Metallopeptidase 9 (MMP-9) is one of the most widely investigated MMPs. It regulates pathological remodeling processes that involve inflammation and fibrosis in cardiovascular disease. #MatrixMetallopeptidase9 #MMPs #ExtraCellularMatrix #ECM #Fibrosis #Cardiovascular
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
📉 According to the ACCORD Eye study, fenofibrate, when added to statin therapy, shows the progression of diabetic retinopathy in patients with type 2 diabetes. Find the study here ➡️ #R3i #hearthealth #diabetes #fenofibrate
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
The R3i International Steering Committee meeting is taking place today February 10 and tomorrow February 11, 2023 in Marrakech, Morocco. Stay tuned as all the conferences will be filmed and posted on our website. Visit this link for more info ➡️ #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
1 year
Lowering low-density lipoprotein cholesterol (LDL-C) with bempedoic acid reduced major adverse cardiovascular events in high-risk patients unable to tolerate statin therapy. Find out more on our website. ��️ #R3i #MedicalResearch #CardioTwitter
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
7 months
World Kidney Day's objective is to raise awareness globally of the importance of kidney health and to increase screening for chronic kidney disease. This year’s theme is #ShowYourKidneys . Visit our site for more info ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
1 year
Reducing your risk of heart attack and stroke could be easier than you think. Here are 7 healthy habits that could save your life. #AmericanStrokeAwarenessMonth #StrokeMonth #Stroke #Cardiovascular #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
This review discusses the evidence for the SPPARMα concept and its therapeutic application, with #permafibrate ➡️ #R3i #residualrisk #residualriskreduction #SPPARM α
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
9 months
Diabetic retinopathy is already the leading cause of vision loss among working-age adults. PPARα agonists have emerged as promising therapies for the treatment of #DiabeticRetinopathy as discussed in this webinar. Sign up here!➡️ #R3i #Diabetes #Webinar
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Is there a link between elevated directly measured remnant cholesterol & an increased risk of ischemic heart disease & myocardial infarction in the general population? The Copenhagen General Population study investigated this question ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
CS can occur due to a rare genetic disorder in which a protein called lipoprotein lipase (LpL) is broken or missing. It can also be caused by the absence of second factor called apo C-II, which activates LpL. When LpL is missing or broken, fat particles build up in the blood.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Atherogenic Dyslipidemia is typical of patients with type 2 diabetes or metabolic syndrome, and is common in patients with established cardiovascular disease. Learn more by visiting our educational slidekit section ➡️ #R3i #ResidualRisk #CVD #diabetes
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
The most important behavioural risk factors of heart disease and stroke are unhealthy diet, physical inactivity, tobacco use and harmful use of alcohol. #AmericanHeartMonth #HeartDisease #CardioTwitter #Cardiovascular #CardiovascularHealth #CardiovascularDisease #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Multiple dosing with this N-acetyl galactosamine-conjugated (GalNAc3) antisense oligonucleotide to APOC3 mRNA reduced triglyceride levels by about 70% in subjects with hypertriglyceridemia. Read the full study here ➡️ #R3i #ResidualRisk #MedicalResearch
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
☝🏼Did you know that #cardiovascular disease (CVD) is a leading cause of death in the world? Check the statistics here ➡️ #R3i #hearthealth #hearthealthy #healthyhear #cardiovascular facts
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Is tight glycemic management associated with a lower risk of nephropathy in type 2 diabetes? Examine the results of four trials that assessed outcomes relevant to this question here ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
PCSK9 is a target for the treatment of #dyslipidemia . Click here for more information. 👉 #medicalresearch #health
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
💬 Did you know that gain of function PCSK9 variants are associated with increased risk of 🫀 ischemic stroke? #R3i #hearthealth #hearthealthy #healthyheart #ischemicstroke
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Does PCSK9 inhibition ⬆️ the risk of diabetes? The ODYSSEY OUTCOMES trial was undertaken to investigate the relationship of lipoprotein(a) concentration with incident type 2 diabetes & the effects of treatment with a PCSK9 inhibitor, alirocumab ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
In R3i we believe that optimizing the control of cardiovascular 🫀🫀 risk factors is critical to reducing the residual risk of diabetes-related microvascular complications in patients with type 2 diabetes. ➡️ #R3i #diabetes #hearthealth
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
📈Current Evidence on Factors Producing Residual Vascular Risk: What are the modifiable risk factors? Find it out in this video 👇 #medicalnews #hearthealth #healthcare #medicalresearch #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Typically, statins are the recommended first-line drugs for lowering LDL-C levels. However, fibrates are more effective than statins for reducing TG levels and increasing HDL. Examine the pros and cons of seven lipid-lowering treatment options here ➡️ "
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
The ideal SPPARM for the treatment of CVD and AS ✅Must be potent and highly selective ✅Must have a similar or greater efficacy to #fibrates in terms of TG- and cholesterol-lowering and HDL-C-/Apo A-1-elevation ✅Must have a reduced side-effect profile compared to fibrates #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
BARI 2D trial: Elevated triglycerides and residual cardiovascular risk. ❤️ Find out more 👉 #medicalnews #hearthealth #healthcare #medicalresearch #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
🧪📈The results of #EVAPORATE provide insights into the mechanism of benefit of high-dose icosapent ethyl demonstrated in the landmark REDUCE-IT study. Find out what it's all about. ▶️ #medicalresearch #medicalnews
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
Do Omega-3 fatty acids contribute to residual cardiovascular risk?🫀🫀 Find out in this study ➡️ #R3i #omega3 #cardiovascular #hearthealth
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Diets have a major impact on our overall health. Professor Frank Hu discussed the role of diet quality in reducing visceral obesity at the Joint Satellite Symposium of the IAS & the International Chair on Cardiometabolic Risk. Read the full commentary ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
🔬Both statins and SPPARMs can reduce the risk/progression of macrovascular complications in people with dyslipidemia and T2D. ☝🏻However, only SPPARMs have the potential to reduce microvascular risk. Learn more here ➡️ #R3i #hearthealth #dyslipidemia
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
The main difference is that type 1 diabetes is a genetic disorder that often shows up early in life, and type 2 is largely lifestyle-related and develops over time. If you have any of the symptoms of diabetes or prediabetes, be sure to get tested ASAP. #DiabetesAwarenessMonth
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
VLDL cholesterol is produced in the liver and released into the bloodstream to supply body tissues with a type of fat (triglycerides). High VLDL levels have been associated with the development of plaque deposits on artery walls, which narrow the passage and restrict blood flow.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Nuclear receptor’s that regulate: ✅ inflammation ✅ obesity ✅ glucose metabolism ✅ lipid metabolism are important therapeutic targets for the treatment of CHD and AS. Learn more #CHD #AS #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
A lipoprotein is a biochemical assembly whose primary function is to transport hydrophobic lipid molecules in water, as in blood plasma or other extracellular fluids. Many enzymes, transporters, structural proteins, antigens, adhesins, and toxins are lipoproteins. #Lipoprotein
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Despite current standards of care aimed at achieving targets for LDL cholesterol, blood pressure and glycemia, dyslipidemic patients remain at high residual risk of CV events. Visit to stay up to date with the latest research and news on residual risk.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
New research from the German Longitudinal Cognitive Impairment and Dementia Study has indicated that the Mediterranean Diet is a protective factor against memory decline and mediotemporal atrophy. Read the full article ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
There are 3 different types of brain stroke: - Ischemic: caused by a blockage cutting off the blood supply to the brain. - Hemorrhagic: caused by bleeding in or around the brain. - TIA: the blockage that stops the blood from getting to your brain is temporary. #StrokeMonth
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
To our knowledge 🤔 icosapent ethyl is the first non-LDL-lowering treatment shown to reduce 📉 coronary artery bypass grafting in a blinded, randomized trial. We review and analyse the study’s outcome here ➡️ #R3i #hearthealth #bypasssurgery #heartsurgery
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
Liraglutide significantly reduced postprandial hypertriglyceridaemia and apolipoprotein B48 excursions in type 2 diabetes patients, independent of gastric emptying. Learn more about the conclusions of this study on our website ➡️ #R3i #Liraglutide #T2D
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In this report, direct measurement of remnant cholesterol identifies an additional 5% of individuals in the general popuation with cholesterol-rich, triglyceride (TG)-poor remnants who are at increased risk of myocardial infarction ➡️ #R3i #Cholesterol
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
May is #AmericanStrokeAwarenessMonth . Did you know that about 80% of strokes are preventable? Visit to find all the content related to cardiovascular and brain health in the #R3i library ➡️ #StrokeMonth #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
EVAPORATE is an ongoing study 📖 using MDCTA to evaluate the effects of icosapent ethyl on atherosclerotic plaque as an adjunct to statin therapy. Read our study review here ➡️ Visit #iscosapentethyl #statintherapy #atherosclerosis
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Data used from 108,559 individuals from the Copenhagen General Population Study show that increased levels of triglycerides (TG) and remnant cholesterol increase the risk of aortic stenosis. Read the study here ➡️ #R3i #Lipoproteins #AorticStenosis
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
📈Evidence shows that higher levels of remnant cholesterol are associated with increased risk for Atherosclerotic Cardiovascular Disease (ASCVD). ➡️Read this study: #R3i #medicalresearch #ASCVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
How does the safety profile with SPPARMα agent pemafibrate differ from fibrates? Watch this video where Prof. Shizuya Yamashita explains it. 👇 #SPPARM α #pemafibrate #R3i #medicalresearch
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
This occurs when plaque builds up in your renal arteries. It often leads to a slow decline in renal function. As your kidneys’ main job is to remove waste from the body, their loss can lead to a problems including weakness, confusion, and abnormal heart rhythms. #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
These factors increase your risk of PAD: - Older age. - High blood pressure or high cholesterol. - Smoking. - Type 2 diabetes. The good news is that some cases of PAD can be managed with lifestyle changes and medication. Talk to your doctor and take control of your health.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
Approximately 6.5 million people age 40 and older in the US have PAD. Both men and woman are affected by PAD; however, African Americans have an increased risk of PAD. Hispanics may have similar to slightly higher rates of PAD compared with non-Hispanic white people. #PAD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In high risk patients with type 2 diabetes, low LDL-C and high HDL-C, statin therapy reduces major cardiovascular events but has an unclear effect on mortality and leaves 63% of events not prevented. Read more at ➡️ #R3i #ResidualRisk #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Metabolic syndrome, a constellation of interrelated risk factors, is thought to be linked by the defect of insulin resistance. Currently, the treatment approach focuses on LDL-C lowering through statin monotherapy or a combination of statin-ezetimibe ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
The SPPARMα concept has brought a new lease of life to the management of atherogenic dyslipidemia. Read the opinions of some of the more than 50 experts who met in Chantilly to discuss the rationale & evidence for SPPARMα ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In patients with atherogenic dyslipidemia, pemafibrate treatment not only significantly increased HDL-C, apo A-I, & apo A-II levels, but also improved indices related to HDL function. Learn more ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
#MedicalResearch | 🤔Do you know the estimated weight loss in 6 months, one and two years? 🥗🏋️This study confirms that weight-loss #diets are most effective during the first 6 months. Read this study for more information. ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
🔬The FIELD trial shows that patients with atherogenic dyslipidemia benefited most from fenofibrate treatment. Learn more here ➡️ #R3i #hearthealth #hearthealthy #healthyheart #fenofibrate #dyslipidemia
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Our mission is to reduce residual vascular risk in dyslipidemic patients. That’s why it's extremely vital that our scientists continually investigate new vascular strategies. Stay informed with the latest findings, sign-up to our newsletters today. #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Clinical trials to date have indicated a favourable benefit vs. risk profile, especially with the lack of elevation in serum creatinine, evident with fenofibrate, and improved renal and hepatic safety. @rauldsf_santos Full article here ➡️ #R3i #SPPARM α
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 months
Recent research has revealed that elevated remnant cholesterol and triglycerides are not just markers but causal risk factors for cardiometabolic multimorbidity. Learn more on our website. ➡️ #MedicalResearch #RemnantCholesterol #CardioTwitter
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
@AaciHealthcare is one of the most experienced organizations in the provision of healthcare organization accreditation and clinical excellence certification services. AACI awarded full medical content certification to the R3i from 2020 through 2023. #R3i #AACI
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Over 50 internationally recognized experts met to discuss evidence for the SPPARMα concept, as part of a Joint Consensus between the R3i and the International Atherosclerosis Society (IAS). ➡️ Visit for more information. #R3i
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New Horizons in Residual Vascular Risk: The SPPARMα Concept

Over 50 internationally recognized experts met in Chantilly to discuss evidence for the SPPARMα concept, as part of a Joint Consensus between the R3i and the...

www.youtube.com
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
The UK prospective Diabetes Study Group 📚 has found that despite improved blood glucose control, 75% of microvascular complications and 84% of macrovascular events are not prevented in patients with type 2 diabetes ➡️ #R3i #hearthealth #diabetes #glucose
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
Plasma metabolomic studies 📖 show that the MedDiet 🥗 is able to attenuate the harmful cardiovascular effects 💔 of branched-chain amino acids, ceramides and adverse metabolites in the tryptophan-kynurenine pathway ➡️ #R3i #hearthealth #mediterraneandiet
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
7 months
You are more likely to develop heart disease if you have: - Diabetes - High blood pressure - Kidney disease - High blood cholesterol - A family history of early heart disease - And if you: smoke; are overweight; don’t exercise; are a man age 45+; are a woman age 55+. #CKD #CVD
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Prof. Nordestgaard graduated in 1985 as a medical doctor from University of Copenhagen. He is chairing the Copenhagen General Population Study and is also a steering committee member of the Copenhagen City Heart Study. Learn more about our members ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
What is hyperApoB and why is it important to clinical practice? Maj Faraj explains the importance of hyperApoB and how it affects T2D’s and CVD patients. Watch now.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
New analysis from the REDUCE-IT study shows that treatment with icosapent ethyl reduces the risk of a first ischaemic stroke by 36%, with no excess in haemorrhagic stroke. Learn more ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Recognizing the early signs can allow a person to get a diagnosis and treatment sooner. Getting appropriate treatment, making lifestyle changes, and controlling blood sugar levels can greatly improve a person’s health and quality of life and reduce the risk of complications.
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
📉The SNuRM concept: In vitro pharmacological profiling shows that fenofibrate acts as a full agonist of PPAR, whereas gemfibrozil acts as a partial agonist due to differential recruitment of coactivators to the promoter region. Read here ➡️ #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
1 year
Prof. Peter Libby discusses the importance of residual inflammatory risk to residual vascular risk. ➡️ Visit for more info. #R3i #ResidualRisk #ResidualRiskReduction #ResidualVascularRisk #ResidualInflammatoryRisk
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How important is residual inflammatory risk to residual vascular risk?

Prof. Peter Libby discusses the importance of residual inflammatory risk to residual vascular risk. Visit https://www.r3i.org for more information.Follow us ...

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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
Remnant cholesterol, also known as remnant lipoprotein, is a very atherogenic lipoprotein composed primarily of very low-density lipoprotein (VLDL) and intermediate-density lipoprotein (IDL). #RemnantCholesterol #RemnantLipoprotein #VLDL #IDL
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
2 years
If a person shows any of these symptoms, even if the symptoms go away, call an ambulance and get them to the hospital immediately. The chances of survival are greater when emergency treatment begins quickly. #Stroke #Cardiovascular #CardioTwitter #CVD #CardiovascularHealth
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In the REVEAL trial, the cholesteryl ester transfer protein inhibitor anacetrapib reduced major coronary events by 9% against a background of well-controlled low-density lipoprotein cholesterol levels with intensive statin therapy. Read more here ➡️ #R3i
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
#Diabetes is now a pandemic #disease . Even with statin treatment to lower LDL cholesterol, patients with diabetes have a high residual CVD risk. Read more in this paper:
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
In patients with atherosclerotic cardiovascular disease receiving evidence-based treatment, targeting inflammation, or further lowering LDL-C provides added clinical benefit; however, neither strategy eliminates the risk of recurrent events ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
3 years
Despite having a mean LDL-C of 80 mg/L, patients with atherogenic dyslipidaemia had a 70% greater relative risk of major CV events than those without (according to the ACCORD trial). Learn more about the trial's findings on slide 8 ➡️
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@R3i_Foundation
R3i Foundation
@R3i_Foundation
4 years
Do you know how fibrates were discovered? 🤔The story begins over 50 years ago, when Imperial Chemical Industries developed an insecticide spray containing phenyl acetic acid... Continue reading here ➡️ #R3i #hearthealth
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