Prof Darrel Francis ☺ Mk CardioFellows Great Again @ProfDFrancis Twitter profile

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

3 years

Can YOU interpret clinical research statistics? Courses of silent, 15-minute seminars, to do on your phone during boring Zoom calls. Do each seminar twice, a few days apart: First time to learn. Second time, GO FOR GOLD! Click here >

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

1 year

As a TPD I am not allowed to comment on the strike other than to wish that everyone gets together soon and settles it amicably blah blah blah. But they never said we can't post pictures wordlessly. So here are two pics.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Several people have asked me whether I think the government is lying about its reason to say Cardiac Arrest resuscitation is NOT an aerosol generating procedure. The government says it is because of science. Science my arse. It is because we don't have enough masks.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

I've realised that some highly educated people find formulae like this difficult to understand.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Good lord, what a happy day! My cup o'erfloweth! 1. Valentina and Eike's updated paper has arrived on the journal website. 2. As I show below, the Big 10 (who I am guessing from twitter comments are some sort of sports governing body) should now be reopening their sport.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

My advice for the general public? DO NOT WORRY ABOUT HEART DAMAGE FROM COVID. "If you as a member of the public are searching the internet for scientific data on heart damage, you are doing it wrong." Uncle Darrel J Condescending but True Facts

fartrade

@Isx33I

4 years

@ProfDFrancis Are there other statistical reports about the incidence of heart related damage? Thanks for your awesome content, a bit hard to digest for the public but trying :D

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Obviously we generally don't give out medical advice on Twitter, but in this case I made an exception. I have anonymised as it was a direct message.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

7 years

If you want to kill people, the most effective way to do this in the modern era (since gun laws and annoying people like the Police will make things awkward) is to persuade people to stop (or never start) a statin. Over the long term, 1 in 10 will be killed by that choice.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

7 years

What does a P value mean? ================== A microtweetorial because I have been watching @anupampom and @JohnTuckerPhD chase each other like this for the last hour, which is distracting me from doing work. Answer this and save them from circular argument. #foamed #meded

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

7 years

RELATIVE RISK, ODDS RATIO, HAZARD RATIO ============================= What are they? Why do we need 3 of the damn things? Which should I use? Are they the same, or different, or a bit samey? An #ORBITA -HQ #tweetorial . #Meded #FOAMed

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Superb EVIDENCE SUMMARY about coronavirus, kindly prepared by Dr Ritesh Maharaj at Kings College London. (Circulated without his permission, sorry)

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

6 years

Why we need Odds Ratio - even though nobody can understand them. My definitive answer !

Prof Darrel Francis ☺ Mk CardioFellows Great Again - @ProfDFrancis

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

We are all doomed by this virus. My last tweet on this earth perhaps? (hat tip to @BogdanEnache ) During viral infection, in ATHLETES, CMR shows: Myocardial EDEMA in 19% acutely, 24% at followup. Myocardial INFLAMMATION in 38% acutely, 48% at followup. Winter is coming.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

1 year

Imperial's new Clinical/Academic Cardiology Fellowship Motto: "We never forget, you have a choice" Open to budding cardiologists, and also to existing cardiology SpRs.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

This is now the officially funniest thing on earth. See in this tweet, the same image everyone has been tweeting, about the T2, T1, or whatever that is all funny or something, in the hearts of people who have had covid?

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

We have failed in our science education of people at large. Many not only do not understand where knowledge comes from but cannot even begin to comprehend it, when it is explained to them.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Wow! 1 out of 136 CPR attempts in COVID achieved favourable neurological outcome at 30 days. Advice from UDHE (Uncle Darrel Health England): *Definitely* get that PPE on first, and if no PPE available, do not attempt CPR. Your team would be providing net killage to the country.

Sarah Hudson

@sarahhudsonuk

5 years

Outcome of CPR in pts with #COVID19 who arrest in hospital – data from 136pts in Wuhan: ◾️Initially ‘successful’ (ROSC achieved) in 13% ◾️Only 2.9% survived for at least 30d ◾️Just 1 pt (0.7%) had a favourable neurological outcome at 30d Source:

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

"When one thing is obviously incorrect, Don't assume that the others are OK." Peter Falk Archives Columbo, 1975

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Hardcore! Now THAT is what I call a controlled experiment. None of your namby pamby "How did you feel about the injection? Did it hurt? What colour syringe did you think would be best?" Nope. "Here's a faceful of Covid." Bosh.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

I expect the Big 10 chappies will be announcing the reopening later today, when they realise that it is LACK OF EXERCISE, not the having of Covid, that causes people to get T1 wotsits. Benching the athletes is the absolute WORST thing to do, to protect their hearts.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Let me be the first to say, I did NOT predict this! I expected the expanded endpoints to tip the balance. Really interesting and shows how excellently the study was done, because they did NOT put the fear of god into the control-arm patients. Congratulations ISCHEMIA team!

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

At last some solid science. Definite permanent heart damage, causing the heart to turn into molecular acid and drill through the chest (as horribly foreshadowed in Alien) on 137% of patients. Even higher if actually exposed to the virus, rather than only worrying about it.

Prof Francois Balloux

@BallouxFrancois

4 years

My aunt Rosie told me that 87% of athletes developed myocarditis, far higher than the 15-33% figures bandied around by some #COVID denialists. This virus is so bad that some who hadn't been exposed to the virus, were among the ones with the worst symptoms.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Dear Nobel Prize Committee, I would like to claim my Nobel Prize please. For curing cancer. Can you post me my medal, or do I have to come and collect it in person? #FOAMED #MedTwitter #Tweetorial

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Incidentally a beautiful illustration of iso-volumic contraction and relaxation times: the tiny intervals when both valves are closed. Thank you @drfallaj for sharing.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Just doing a scan "for peace of mind" is a bad idea. Their mind was at peace until you told them to have a scan.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Look, what's the matter with everyone. The revised Jama Cardio paper is brilliant. It's an all-clear! The interesting features on the scans in Covid survivors are real, but they are caused by the risk factors, not by the covid.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

I promised @rallamee I would stay off Twitter. But "forever" is a long time in science. John Mandrola, whom I had the honour to lecture with at Roy Coll Phys Edinburgh last week, asked me what I thought of this "complaint letter" he got about his blog article mentioning ORBITA.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

A second wave, but the deaths are primarily in places that were not hard hit with deaths before.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

3 years

I see Prof Chloroquine has decided to sue Elisabeth Bik for annoying him by pointing out the dubious features in his claims.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

11 months

I am so proud of these tremendous people with whom I have been blessed, but especially @rallamee .

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Confused by the Corona news on this wondrous day, after fending off weeks of intravenous laser bleach and chloroquisade te pointes? Two (2) [TWO] trials reported on the same day. Let's have a look!

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

"Science is a method for becoming slightly less wrong, by a sequence of prediction, experiment and surprise." D Francis J Blindingl Obv Epigrams 2020

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

If we as a profession are happy to retweet gibberish, we can't blame universities, sports associations and governments for talking nonsense. 8-) Venk Murthy has just sent me this. I have no idea what a Big Ten is, but it is getting taken in by the nonsensical numbers.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

11 months

ORBITA-2

A Placebo-Controlled Trial of Percutaneous Coronary Intervention for Stable Angina | NEJM

Percutaneous coronary intervention (PCI) is frequently performed to reduce the symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in patients who are not receiving...

www.nejm.org

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

@VPrasadMDMPH Hi Vinay. Don't jump to conclusions. Try reading another paper too, and reading no paper. And monitor your tingliness every minute or so...

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Can YOU interpret clinical research statistics? A course of silent, 15-minute seminars, to do on your phone during boring Zoom calls. Do each seminar twice, a few days apart: First time to learn. Second time, GO FOR GOLD! Click here >

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Yesterday I clicked on a link on Twitter, and then didn't get to see the content as I had to do boring stuff instead. Anyway, today after I closed some browser tabs I saw this on my screen.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Here is the deadly coronavirus that did this horrible thing to people's hearts.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Video explanation of a protocol for suspected coronavirus patients needing emergency cath lab procedures. Presented by Emma our radiographer with expertise in infectious disease management, Dr Ghada Mikhail, and filmed/edited by Dr Iqbal Malik & daughter.

COVID and urgent cardiac procedures at Imperial College NHS Trust

This video explains how operators should protect themselves during cardiac emergencies in the cathlab with patients with COVID.

www.youtube.com

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

When @LCC_DrMalik circulated YET ANOTHER document attachment on Covid advice from NHS colleagues nationwide, I of course only pretended to read it. I got my caught for lying when people asked what I thought and I said it was "very useful". This was the content, I later learned.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Science isn't knowledge. It's a method of acquiring knowledge.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Great progress! 1 million vaccinated in USA 500,000 in UK All within 7-10 days of first jab. Amazing.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

This story is interesting:

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Why can we put a man on the moon but not provide facemasks for our front line workers?

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Prize for the first person to spot what went wrong here. (First author is an old friend so I am sure she won't mind me pointing it out. Great study! All publicity is good publicity Valentina!)

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

1 year

Just starting training in Cardiology? Or just curious about echocardiography? Free online echo course for absolute beginners - all welcome!

Day 1: Say hello to the heart

Learn the major structures on one standard view

storage.googleapis.com

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

I was going to do a tweetorial today, but I won't. My head exploded reading this article. Interesting, timely, superbly literate and scientifically astute. The sort of article you would be delighted for your daughter to marry.

Pandemic Science Out of Control

Poor-quality research, media hype, lax regulatory oversight, and vicious partisanship are impeding the search for effective treatments for COVID-19.

issues.org

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

One terrifying possibility from the NIAID press release, pointed out to me by @venkmurthy

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

6 years

Interpreting Odds Ratios in ordinary language

Prof Darrel Francis ☺ Mk CardioFellows Great Again - @ProfDFrancis

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Global health advice. When is blocked off by Elsevier et al, what is a person to do? Easy! Go here and click one of the big-font links at the top. They seem to keep track of which routes to Alexandra are currently open.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

@AAMortazavi @bogdanenache Some people are only happy when they are unhappy.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

That's why frightening people with news stories is so harmful. I can't say "no it is definitely wrong". But only in the same way as I can't say "there is no Loch Thames monster".

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Somehow I find myself cornered into being a world expert on everything. (My daughter used to believe that. But that was when she was three after a remorseless campaign of me emphasising that point.)

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Anything I say to give hard-pressed doctors a well-deserved laugh, has a risk of making some of them angry. But this will amuse not only to every doctor, but everyone who has a science degree, and indeed a many other people who have merely been to school

Scientists Have Utterly Failed to Prove that the Coronavirus Fulfills Koch’s Postulates

Amory Devereux and Rosemary Frei About 150 years ago, scientists painstakingly constructed a set of principles that can prove whether a particular microbe is the cause of a specific disease or is j…

off-guardian.org

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

11 months

Wow! I had been assuming this was going to show weight loss -> lower BP & cholesterol etc -> Fewer events, and that would be a very gradually-evolving effect. This shape of a seemingly constant relative risk reduction throughout suggests an instant benefit of eating less!

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

As a distraction from Corona stress, let's have a short tweetorial.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Yes it is intellectual elitism but that is a part of science. Not all opinions are of equal value. A scientific reputation is built over decades and destroyed in a day. That is why scientists are so careful in their speculation and so quick to correct errors.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Fascinatingly sad story. I'm not sure what Covid has to do with it though. Is poor old Covid being blamed for everything now, including a landlord not wanting to continue leasing out an apartment? Maybe I should punch somebody in the face. "Sorry, that was the Covid talking."

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

Happy Memorial Day Weekend to all cardiology fellows! I thank m'learned friend Prof Simon Thom for showing me the funniest paper of the year. I will discuss it tomorrow. What approach should I take? #cardiotwitter

Be nice

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Be respectful

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Be kind

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No just be yourself

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

In a spirit of solidarity with actual scientists, I did an interview with Eike Nagel, the senior author of the famous JAMA Cardio paper that accidentally shut down some US Sports.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

So now I am a believer in remdesivir. "But Dr Francis, you were laughing at it before, so you just reversed your opinion?" Yes. It's called thinking.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

For the education of the general public, this is how a scientist reads a news story. Step 1. Look at the important bit of the story.

New Insights into How COVID-19 Causes Heart Damage

Gladstone scientists discover how the novel coronavirus damages heart muscle cells, and creates a system that can be used to screen potential therapies

www.biospace.com

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

When this happens ...

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Scientific proof of how chloroquine works on coronavirus! And from an unimpeachable source! It's not an RCT but it is real world data, what more could you ask for?

Jesus Christ⌚

@Jesus_FH_Christ

4 years

Hydroxychloroquine's effectiveness on a virus.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

This is the funniest thing on earth. Now we know why the finance industry are in such a mess. The people who charge you money to lose your money, are busily doing it. Moronic commentary too. Let me explain.

CNBC Now

@CNBCnow

5 years

BREAKING: Gilead shares surge after-hours as Stat News reports that the company's Remdesivir trial for coronavirus patients is seeing rapid recoveries according to early data.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

This reminds me of the old medical student joke. "What is the prognosis of this condition?" "Um, I can't remember." "A clue is the fact that you are holding the organ in your hands, during a post mortem dissection."

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Turns out that MRI evidence of oedema and of inflammation happens not only during the common cold (and followup), but also at baseline (BEFORE they caught the cold).

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Today's Tweetorial is courtesy of my friends Thomas Treibel, Charlotte Manisty, and James Moon! First the challenge. What do you make of this?

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Q. What about ordinary people wondering if Coronavirus has infected them without their knowledge and is causing heart disease? A. I don't think ordinary people should worry about this at all. (Excellent!)

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Right got to have a socially distanced samosa ... errrrr ... visit with my parents.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

"At a cardiac arrest, if you do not have PPE, go and get it on first, and only then start chest compressions. Even if the arrested patient is me."

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

3 years

I'm so excited! PCI proven to save lives! And we in ORBITA have played our part!

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

This is a new low point for AHA. Is it *so* dependent on industry money? We need to be more careful of its interpretations of other things. If it can be so wrong about this, which we only happen to be able to spot as wrong, it might be wrong about other things harder to spot.

Harlan Krumholz

@hmkyale

5 years

Headline at #AHA19 contrasts with take home from major newspapers… AHA portraying #ISCHEMIA as positive: ‘Early intervention vs conservative therapy can improve angina symptoms…’ Interesting. Not the main finding in my view.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

So we can't really blame journalists. We ourselves, in medicine, can't be bothered to read what we tweet. Hahaha The disclaimer should be: "Retweet doesn't imply that I have even looked at it, never mind approve it!"

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

If you are about to do an unblinded trial of a symptom-relieving treatment: Don't bother. Just make up the results. We know it will be positive. Embezzle the money. Spend 1/3 on cars, 1/3 on women, and waste the rest. You will save patients the effort and benefit the economy.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

I'm quite annoyed that our hospital illegally recorded our high level multidisciplinary team meeting. Anyway I wasn't the instigator. I was just caught up in the emotion, your honour. I can't explain why I threw a chair at the vascular surgeon. I suddenly have memory loss.

Dorian L. Beasley MD, FACC

@cardiojaydoc02

4 years

Cardiologists when they here the phrase “cardiac clearance” for non-cardiac surgery.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Holy cow!

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

7 years

Intention To Tweet ============ 1. Why is intention-to-treat the ONLY right way to interpret trial results? 2. Why are these fine gentlemen wasting their prayers? Tweetorial for cardiology fellows from ORBITA-HQ #cardiology #meded #foamed

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

I'm ashamed of being a member of the human race. Not only the US, but now Europe, is officially stealing things from planes that stop for fuel.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

3 years

When your patient adverse symptoms on statins, what should you do?

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

5 years

I am entitled to my opinion on how to fly a plane. But it is a shit opinion.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

SENSITIVITY = Get people WITH the disease. In what proportion is the new test correct? SPECIFICITY = Get people WITHOUT the disease. In what proportion is the new test correct? D Francis J It Surely Can't Be This Eas. 2020

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Just because something is strictly speaking unknown and indeed *unknowable*, does not mean that it should be treated as having a 50 50 probability. That is a recipe for going back to the dark ages. "She could be a witch!” "Or she may not be" "Well let's just be safe..."

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

3. Remember Uncle Darrel's rule. If 30% of smokers need glasses, and it is the same regardless of whether they smoked 1 per day for just 6 months, or 40 per day for 40 years, then it is a fair bet that the needing of glasses is nothing to do with the coffin-nails.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

"Only do a test, if there is a realistic chance of a result which has a realistic treatment, that is realistically helpful." D Francis J Societies Not Wanting To Be Overrun By Health Anxieties, 2020

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

6 years

If anyone wants to know how incorrect causal inference arises in cardiology, there's no need to do a PhD on it. It's encapsulated in this thread. Unlike most of my threads it has a happy ending though ! First, a whole load of unsuspecting patients have PCI.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Josh isn't the first person to think of this, merely the last.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

The problem with not retracting an erroneous study, is that this keeps happening. Nicole, I don't blame you for not realising that the numbers are almost all wrong. Because @JAMACardio has let half a million people download it without telling them what it already knows.

Nicole Saphier, MD

@NBSaphierMD

4 years

German study in JAMACardiology found 60% of 100 adult patients who recovered from COVID19 had findings of ongoing myocardial ❤️ inflammation similar to what some young adult athletes have reported. Such long-term complications are factors in whether college athletics will resume.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

How to tell that you are REALLY interested in your science.

@LaBonneLaB

@labonnelab

4 years

I feel seen

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

The reason why I recommend the general public not to worry about such things is that there is nothing useful you can do about the worry, other than just worry. The whole point of having scientists to do science and doctors to explain it to you, is so that it is done well.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Suppose, Alice and Bob, two ORBITA HQ PhD students, ask to be put on the same project, so they can spend more time with each other, within the bounds of social distancing rules (and decorum).

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Thank you to an anonymous person, for looking after her neighbour kindly. Negative thanks for sending me a duff story. So overall, net neutral. 8-) (Details in thread that follows)

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Uncle Darrel's rule of diseases is: "The more ill you are, the more ill you are."

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

The mistake is for people who cannot distinguish between a scientific hypothesis and a scientific conclusion, to write - in magazines or on Twitter - that people's hearts are dissolving into mush. It's frankly embarrassing for a species that has sent people to the moon.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

In a world where people seriously believe in ghosts, astrology, alien abduction, 9-11 conspiracy, flat earth, faked moon landings, creationism, etc, there are risks to encouraging formation of opinions, without prior formation of skills to form those opinions wisely.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Who is your cardiologist? How did he or she conclude you have developed heart failure from Covid-19? Which medical community? People who went to med school and passed the exams? Or people who tweet about health? What makes you think 1 million people have died of heart damage?

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

3 years

Cruelly accurate!

Ankur Kalra

@AnkurKalraMD

3 years

This is quite brilliant! 😆— @ShelleyWood2 @TCTMD @michaelTCTMD @ToddNeale @TCTMD_Caitlin @TCTMD_Yael @mmamas1973 @SrihariNaiduMD @DLBHATTMD @rwyeh @bnallamo @virani_md @khurramn1 @safinmc @ShahzebKhanMD @dranulala @robmentz @WilliamZoghbi @SuzanneJBaron @Drroxmehran

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

I actually cannot believe that this man has been to school, never mind got elected president. It shows you how irredeemably thick one can be, and yet be successful. There's hope for us all!

Elliot Tapper

@ebtapper

4 years

Worst journal club ever

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Scariest thing in the world is not Covid. It is waking up and hearing that you are in an argument with Steve Nissen, the fearsome science monster of Cleveland Clinic. Apparently Medscape's Patrice Wendling is doing an article shortly. Some rumour of a lawsuit also.

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Let me be the first to say, "Good riddance, bullshitters."

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Prof Darrel Francis ☺ Mk CardioFellows Great Again

@ProfDFrancis

4 years

Someone comes to you with "data" about an exciting new treatment? Check whether it is an RCT. If it isn't, punch them in the face. Brutally (but humanely).

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