عبدالله الجاسرAbdullah Aljasser
5 years
Polymer backbone:
- The most commonly used biodegradable and non biodegradable copolymers are PGA and PEG and HPMA, respectively
- Clearance is dictated by Mwt
• Clearance rate decreases as Mwt increased
• Lower than 40kDa, renal clearance
• More than 45kDa, MPS clearance