Oxford Nanopore @nanopore Twitter profile

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Oxford Nanopore

14 days

Stay ahead of the curve and reserve your spot at #nanoporeconf . Dive into groundbreaking insights from speakers using nanopore technology across diverse research fields. Get hands-on with the tech, catch the latest updates and connect with the Community:

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Last Seen Profiles

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Oxford Nanopore

@nanopore

3 years

Wonder if they have tried a quick reversal of the current?

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Oxford Nanopore

@nanopore

10 months

A complete picture of the genome, finally. At #ASHG23 , discover how #nanopore technology can resolve even the most complex genetic and epigenetic variants, and provides the scalability for any sequencing project — from one human genome to 1000s.

A complete picture of the genome, finally.

nanoporetech.com

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Oxford Nanopore

@nanopore

7 years

Landmark paper in @naturemethods describes @nanopore direct sequencing of RNA: no reverse transcription requirement, native sequencing for modified bases, easy prep, low bias, full length transcripts

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Oxford Nanopore

@nanopore

5 years

200 Oxford Nanopore sequencers have left UK for China, to support rapid, near-sample #coronavirus sequencing for outbreak surveillance. Read the full story here: #nCoV19

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Oxford Nanopore

@nanopore

2 years

Not Wordle, just an array of nano-scale channels through which single DNA strands are passed, in each case causing tiny modulations in an ionic current that can be analysed to elucidate the order of DNA bases on that strand

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Oxford Nanopore

@nanopore

7 years

First continuous DNA read of more than a million bases (>1Mb) achieved with @nanopore . Congratulations @martinalexsmith @kinghorngenomes @garvaninstitute . Read more:

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Oxford Nanopore

@nanopore

4 years

Nanopore technology is ideal for structural variant detection at scale. Here's a 189,900-base read, from real nanopore data — watch on to see how much information you get from one nanopore read* #ASHG20 *Would've gone longer but it wouldn't fit on screen

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Oxford Nanopore

@nanopore

10 months

Attending #ASHG23 ? Grab a coffee and join us at our two Data for breakfast sessions. Learn about resolving variation in the human genome and using adaptive sampling for targeted pharmacogenetic sequencing. Learn more:

Data for breakfast at ASHG 2023

nanoporetech.com

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Oxford Nanopore

@nanopore

9 months

Today @Apple highlighted how their M3 silicon chip provides powerful, accessible compute — citing the ability to run the complex analysis required for DNA/RNA #nanopore sequencing, by anyone, anywhere in the world. #AnythingAnyoneAnywhere #AppleEvent

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Oxford Nanopore

@nanopore

5 years

Gordon Sanghera @gsanghea just opened #nanoporeconf reminding us why we are all here together. Please follow our tweets over the next few days from @nanoporeconf !

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Oxford Nanopore

@nanopore

3 years

From an initial sketch on the side of the road, to the only sequencing technology that provides native, real-time analysis of DNA & RNA fragments of any length, in fully scalable formats. Nanopore sequencing has come a long way:

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Oxford Nanopore

@nanopore

6 years

We announced today that we are building a new high-tech, high-throughput manufacturing facility in Oxford. And it’s designed to look like a MinION. Read more about this and other announcements today:

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Oxford Nanopore

@nanopore

2 years

We are pleased to announce the release of a number of new V14 kits. Our newest kits in combination with latest nanopore R10.4.1 offer Q20+ (≥99%) raw read accuracy with high sequencing yield. See thread below for more info. 1/5

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Oxford Nanopore

@nanopore

6 years

Single read of 2.3 Mb. Repeat: single read of 2.3 Mb 🐳

Matt Loose

@mattloose

6 years

Turns out that @nanopore reads are longer than we thought. Longest we’ve found now is 2,272,580 bases. I reckon this is a small baby blue whale! info here:

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Oxford Nanopore

@nanopore

5 years

Today the R10 nanopore has been released into an early access programme. Internal results show Q50 on a small genome, read more here:

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Oxford Nanopore

@nanopore

4 years

In light of the #COVID19 situation globally, we’re moving London Calling 2020 #nanoporeconf to an online event that is open to all. We’re working on this now and will provide updates. In the meantime you can register your interest to join here:

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Oxford Nanopore

@nanopore

4 years

We’re in the advanced stages of developing #LamPORE , a new assay for rapid, highly scalable, low-cost #SARSCoV2 detection for #COVID19 , that uses @nanopore sequencing. Our aim is to enable more people to be tested, more quickly, in more locations: 1/4

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Oxford Nanopore

@nanopore

10 months

We’re hosting two Colab sessions at #ASHG23 . Join us to find out how long #nanopore reads enable the accurate detection of genetic and epigenetic variation, and how researchers are implementing nanopore sequencing to gain a more complete understanding of genetic diseases.

Colab sessions at ASHG 2023

nanoporetech.com

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Oxford Nanopore

@nanopore

3 years

A new "Q20+" @nanopore sequencing kit is now being tested by a number of developers in the Community. This has produced raw single-molecule, single-pass sequencing reads above a modal 99% accuracy, or Q20+ internally and externally. Read more: [1/2]

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Oxford Nanopore

@nanopore

6 years

The MinION Mk1c combines the real-time, rapid, portable sequencing of MinION and Flongle with real-time, powerful GPU based computing and a high resolution screen. Pre-order in the store: or register your interest:

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Oxford Nanopore

@nanopore

6 years

On the cover of @naturemethods , Read "Highly parallel direct RNA sequencing on an array of nanopores"

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Oxford Nanopore

@nanopore

4 years

2020 has been a year of intense innovation, and we are delighted to be partnering with teams at the UK's Department of Health and Social Care to roll out LamPORE, a new generation of COVID-19 test. 1/3 Read more here:

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Oxford Nanopore

@nanopore

2 years

Delighted to see @naturemethods has chosen 'long-read sequencing' as their method of the year, a refection of the amazing community work. Long native #nanopore sequencing reads simplify assembly, can span repetitive genomic regions & identify SVs: 1/n

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Oxford Nanopore

@nanopore

5 months

Reveal more about the underlying mechanisms of cancer. Join us at #AACR24 to hear how researchers are generating ultra-rich #nanopore data — resolving SNPs, SVs & epigenetic mods, at the haplotype level from a single dataset — to gain an unprecedented view of cancer. #WYMM #AACR

Join us at AACR 2024

nanoporetech.com

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Oxford Nanopore

@nanopore

9 months

What you're missing matters when it comes to finding answers to unsolved questions in human disease. #wymm Find out more at our industry session at #ASHG23 :

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Oxford Nanopore

@nanopore

5 years

CB: Methylation is now integrated into basecalling, for free — m6A and 5mC are available as standard, but it’s also possible to train for any modification #GenomeScience2019

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Oxford Nanopore

@nanopore

4 years

Researchers at the @TheDohertyInst in Australia publish the first *native RNA sequence* of #SARSCoV2 , using @nanopore , showing insights into subgenomic mRNA production and base modification in the virus. @lachlanjmc @Miranda_E_Pitt @drdebwilliamson et al

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Oxford Nanopore

@nanopore

3 years

From an initial sketch on the side of the road, to the only sequencing technology that provides native, real-time analysis of DNA & RNA fragments of any length, in fully scalable formats. Nanopore sequencing has come a long way: #anythinganyoneanywhere

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Oxford Nanopore

@nanopore

6 years

We’ve released an upgraded flow cell for DNA/RNA sequencing on MinION/GridION: ‘RevD’. It runs for longer and gives you greater yields – as much as 30Gb per flow cell. Read more:

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Oxford Nanopore

@nanopore

5 years

The MinION Mk1c combines the real-time, rapid, portable sequencing of MinION and Flongle with real-time, powerful GPU based computing and a high resolution screen. Pre-order in the store: or register your interest:

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Oxford Nanopore

@nanopore

5 years

Flongle now available to buy, after feedback from early access users. An adapter for the portable MinION or benchtop GridION DNA/RNA sequencers. It's designed to offer rapid insights at low cost: anyone, anywhere, any time. #WhatWouldYouFlongle ?

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Oxford Nanopore

@nanopore

5 years

We're pleased to announce that R10 flow cells will start shipping from 10th July onward. They're available to buy in the store — simply select the R10 pore type when ordering your flow cells. You'll find a full R10 update in the Community*: *login required

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Oxford Nanopore

@nanopore

4 years

New protocol alert! We're pleased to introduce a new protocol for dual barcoding up to 2,304 different samples in one experiment, reducing the reagent cost per sample to as low as $2.72. Find out more in the Community (login required)

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Oxford Nanopore

@nanopore

2 months

Introducing the MinION Mk1D. #nanoporeconf

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Oxford Nanopore

@nanopore

4 years

Towards real-time targeting/enrichment/other sampling on the @nanopore sequencer, not in the sample prep: two new preprints from Kovaka/Payne show adaptive sampling using ‘Read Until’ API, find out more here: 1/3

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Oxford Nanopore

@nanopore

5 years

Oxford Nanopore’s new factory, the MinION Building, has come online. Using new, high-tech automation processes, over 4-5 years we will be able to scale to production of more than a million flow cells/year [1/3]

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Oxford Nanopore

@nanopore

5 years

Today we’ve introduced R10.3 flow cells to the store. Building on R10 — which was recently shown to produce 99.995% single molecule consensus accuracy — R10.3 provides increased throughput and better raw read accuracy. Read more:

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Oxford Nanopore

@nanopore

1 year

Oxford Nanopore was the first to enable direct RNA sequencing. The new kit (RNA 004) and flow cell for direct RNA sequencing demonstrates increased accuracy and output, with the potential to unlock a new field of biological analysis. #nanoporeconf

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Oxford Nanopore

@nanopore

2 years

Congratulations to the Telomere-to-Telomere (T2T) Consortium who have published their paper in @ScienceMagazine on the first truly complete 3.055 billion base pair sequence of a human genome: 1

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Oxford Nanopore

@nanopore

4 years

We’ve had a huge surge in enquiries in the past week from researchers wishing to use @nanopore for #SarsCoV2 sequencing in #COVID19 . It’s now being used in 30 countries and we are supporting users in >40 more countries to get started. This is how we’re supporting users...1/10

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Oxford Nanopore

@nanopore

3 years

From an initial sketch on the side of the road, to the only sequencing technology that provides native, real-time analysis of DNA & RNA fragments of any length, in fully scalable formats. Nanopore sequencing has come a long way:

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Oxford Nanopore

@nanopore

4 years

Using nanopore technology you can analyse any length of native DNA or RNA. It's the only sequencing tech to enable real-time analysis, in fully scalable formats — from pocket to population scale. But how does it actually work? Watch on to find out.

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Oxford Nanopore

@nanopore

11 months

Return of the Mac! MinKNOW now supports real-time basecalling on @Apple devices for the first time. The M1/M2 family of Macs provide an alternative easy-to-use solution for customers who want to perform real-time analysis, anywhere. Read more: #AppleEvent

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Oxford Nanopore

@nanopore

3 years

As DNA passes through a nanopore, its sequence is decoded in real time. Using adaptive sampling, it's possible to reject sequencing reads that are not of interest — leaving the nanopore available for your targeted region of interest: #TechTuesday

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Oxford Nanopore

@nanopore

2 years

We are pleased to announce a new protocol explaining how to recover a DNA library mid-sequencing run. This protocol has been developed to enable precious samples to be recovered and transferred to a new flow cell for continued sequencing. Learn more:

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Oxford Nanopore

@nanopore

10 months

At #ASHG23 we are hosting several demos at our booth. From end-to-end, automated #nanopore sequencing to loading a flow cell. Learn about PCR-free targeted gene panels and how you can comprehensively view #haplotype -resolved variation and #methylation in the #human #genome .

Live demos at ASHG 2023

nanoporetech.com

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Oxford Nanopore

@nanopore

10 months

The accurate measurement of telomere length is challenging due to its repetitive nature. At #nanoporeconf , @tobiastschmidt will discuss how nanopore technology can overcome this challenge by resolving these long & repetitive regions. Read here:

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Oxford Nanopore

@nanopore

6 years

Oxford @Nanopore raises £100M ($140M) from global investors GIC, CCBI, @Hostplus . More innovation, opening new high tech manufacturing facility, commercial expansion.

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Oxford Nanopore

@nanopore

3 years

From Team London Calling: thank you so much for being a part of LC 2021 online (and giving us an excuse to come back to the office!) 😊 hope to see you in person soon! #nanoporeconf

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Oxford Nanopore

@nanopore

4 years

“192 #SARSCoV2 genomes in 6 hours”- amazing work in London

Paola Resende

@PaolaResende1

4 years

Running @nanopore sequencing at full capacity #COGUKLondon 🇬🇧 192 #SARSCoV2 genomes in 6 hours monitoring by #articRAMPART @uclpgu @uclgenomics #COVID19 #COGUK #gridION #MinION

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Oxford Nanopore

@nanopore

2 years

Oxford Nanopore Technologies is pleased to announce a new collaboration with @10xGenomics , bringing single-cell and spatial full-length isoform transcript sequencing to any laboratory. Find out more:

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Oxford Nanopore

@nanopore

6 years

MinION Mk 1c will combine MinION, MinIT for rapid data analysis and a screen, for a one-stop palm sized fully portable sequencing system, fully connected. Targeting mid 2019 for release but we'll open the shop in January. #nanoporeconf

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Oxford Nanopore

@nanopore

6 years

Introducing Flongle, for rapid, cost effective nanopore sequencing of smaller samples, anywhere. In lab for amplicons/QC/targeted regions/smaller genomes. Outside lab, extra potential for diagnostics, food/water testing, education. #nanoporeconf #Flongle

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Oxford Nanopore

@nanopore

9 months

Ask bolder questions. Make no compromises. What you’re missing matters. #wymm Find out more: #ASHG23

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Oxford Nanopore

@nanopore

3 years

The P2 is now available to pre-order! P2 is designed to bring low-cost nanopore sequencing for large genomes or high-throughput long-read transcriptomics, without the requirement for capital investment & large infrastructure. Find out more: #techtuesday

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Oxford Nanopore

@nanopore

3 years

A huge milestone in human #genomics published by the #T2T Consortium this week — the first complete human genome, and single largest addition of new content to the human genome in the past 20 years!

Adam Phillippy

@aphillippy

3 years

The #T2T Consortium is excited to release a series of preprints in the coming weeks that describe the assembly and analysis of the first truly complete human genome! 🎉 I will append the papers as they appear to this 🧵, and you can find all our data here:

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Oxford Nanopore

@nanopore

4 years

Have you tried Pore-C yet? Chromatin conformation capture meets long-read nanopore sequencing, providing multiple contacts in single, long nanopore reads. Reveal dynamic interactions in the genome, improve assemblies, and identify long-range SVs. 1/9

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Oxford Nanopore

@nanopore

5 years

Pore-C is out! The pre-print shows how Pore-C can be used to detect chromatin structure, confirm the connectivity of complex SVs, and scaffold assemblies. Protocol and tools to follow soon!

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Oxford Nanopore

@nanopore

4 years

Nanopore sequencing has been used to smash the record for the largest animal genome ever assembled. The Australian lungfish genome is 43 billion base pairs long — 14x larger than the human genome & 30% larger than that of the previous record! Read more: .

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Oxford Nanopore

@nanopore

4 years

SR: This week Oxford Nanopore has generated modal *raw-read accuracy* of 99.1% (99%=Q20) using a new chemistry with Bonito, delivered on internal validation sets with a substantial fraction of these raw reads above Q20 #nanoporeconf

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Oxford Nanopore

@nanopore

7 years

Human genome assembly using only @nanopore in @NatureBiotech . inc assembly/phasing of entire 4Mb MHC locus, telomere repeat length, closure of gaps in ref GRCh38

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Oxford Nanopore

@nanopore

3 years

Introducing : a pilot-stage project designed to support faster, more localised DNA sequencing of #criticallyendangered species, using the latest ultra-long read approaches from @nanopore . Read more:

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Oxford Nanopore

@nanopore

2 years

In this paper published in @NatureBiotech , @weilgunyl , @ewanbirney & @mattloose present: BOSS-RUNS — a new method of targeted sequencing that can dynamically update target decisions during an experiment & without experimenter interactions. Read here:

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Oxford Nanopore

@nanopore

4 years

Two fantastic papers in Nature Biotech today, demonstrating the role adaptive sampling could play in understanding genetic disease. Read more here: @mattloose @alexomics @samkovaka @mike_schatz

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Oxford Nanopore

@nanopore

3 years

As DNA passes through a nanopore, its sequence is decoded in real time. Using adaptive sampling, it's possible to reject sequencing reads that are not of interest — leaving the nanopore available for your targeted region of interest: #TechTuesday

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Oxford Nanopore

@nanopore

3 years

Through field-based genetic sequencing courses, Zane & @u_ikiam are also working to train Ecuadorian researchers & students in field genomics, made possible by #MinION . Here you can see Walter Quilumbaquin & Grace Reyes holding MinION at the research station 📷: @ZaneLibke 5/7

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Oxford Nanopore

@nanopore

4 years

Scientists from @UniofOxford , @OUHospitals , @PHE_uk , @sheffielduni & @sheffieldhosp have published their evaluation of LamPORE in more than 500 clinical samples, showing 99.1% sensitivity and 99.6% specificity:

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Oxford Nanopore

@nanopore

3 years

With PCR-free nanopore sequencing, epigenetic modifications, including methylation, can be detected without any special library prep. Here’s some of the latest stats from our recent performance benchmarking for nanopore methylation analysis. 1/10

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Oxford Nanopore

@nanopore

8 years

MinIONs are now with NASA, preparing for launch to ISS for first DNA sequencing in space! @ISS_Research @Astro_Kate7

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Oxford Nanopore

@nanopore

4 years

An update on how the latest algorithms are driving accuracy gains for nanopore sequencing:

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Oxford Nanopore

@nanopore

3 years

189,900-bases sequenced: 1,658 bases inserted, 937 bases deleted, 248 SNVs, 4,825 CpG methylations. One read.

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Oxford Nanopore

@nanopore

5 years

43 Gb from a single MinION flow cell! Unbelievable results; huge congratulations to the team :)

Soeren Michael Karst

@SorenKarst

5 years

Here is the proof @OHartwell , although it was 'only' 43 Gbp after basecalling ;) . ~5000 bp amplicons prepared with SQK-LSK109 and run on a single R9.4 flowcell on the MinIon for 2 x 48 hours. No library top-off or washing, only added extra SQB a couple of times.

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Oxford Nanopore

@nanopore

3 years

Phenomenal work from a truly collaborative team — sequencing whole human genomes and identifying disease-causing variants in less than 8 hours, to improve prognosis in critically ill patients. And a Guinness World Record to add to that achievement!

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Oxford Nanopore

@nanopore

3 years

And it’s goodnight from us! The #nanoporeconf behind the scenes team, hoping you had a great time watching talks, reading blogs, tweeting and networking!

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Oxford Nanopore

@nanopore

6 years

Congratulations @khmiga and team on linear assembly of human Y centromere in @NatureBiotech Watch Karen's talk on this work here:

Linear assembly of a human centromere on the Y chromosome

Nature Biotechnology - Repeat regions in the human Y chromosome centromere are assembled using long-read nanopore sequencing.

www.nature.com

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Oxford Nanopore

@nanopore

2 years

Our new plasmid sequencing workflow provides an end-to-end solution for the rapid generation of highly accurate sequence information across the entire plasmid, in house. Find out more and give it a go for yourself!

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Oxford Nanopore

@nanopore

4 months

Despite high breast cancer mortality rates, research in Caribbean women has been underrepresented — until now. At #nanoporeconf , @carikaelshae will discuss her study focusing on the unique genetic markers of breast cancer in Caribbean women. #AACR24

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Oxford Nanopore

@nanopore

6 years

"Over 1,000 miles from shore we were able in 48 hours to identify the presence of white sharks in the water column beneath the ship using nanopore eDNA sequencing at sea,” — Barbara Block, Stanford University

New eDNA tool 'changes everything in marine science'—how it works

With eDNA, or environmental DNA, scientists can count fish and other animals just by collecting a small sample of water.

www.nationalgeographic.com

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Oxford Nanopore

@nanopore

4 years

Now available to purchase in store: Native Barcoding Expansion (96) kit, allowing higher numbers of samples to be run on a single flow cell - including for #SARSCoV2 whole genome sequencing protocol. Find out more:

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Oxford Nanopore

@nanopore

4 years

Introducing the new MinKNOW App — now available to download on iOS and Android devices! Use the App to start your run, monitor progress in real time and manage your device, remotely. Find out more:

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Oxford Nanopore

@nanopore

3 years

Visitors at Oxford @Nanopore today

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Oxford Nanopore

@nanopore

5 months

London is Calling. In just over two months we will be opening the doors for the 10th edition of #nanoporeconf . Join us in person or online (for free) to hear groundbreaking genomic research from the Nanopore Community. Get your ticket here:

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Oxford Nanopore

@nanopore

1 year

Yesterday marked the opening of (and first shipment from) our Australian warehouse in Sydney. This investment in ‘scaling up’ will allow our products to reach more customers, quicker, enabling more high-impact research to be done in the region. #anythinganyoneanywhere

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Oxford Nanopore

@nanopore

8 years

On Monday it goes to space, but today it is with the stars. The moment when @DannyDeVito met the @nanopore MinION!

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Oxford Nanopore

@nanopore

4 years

How many of you have binge-watched @netflix 's brand-new series #Biohackers already? The eagle-eyed amongst you may have spotted some very familiar looking tech in Ep. 5!

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Oxford Nanopore

@nanopore

9 months

From 20 bases to 4,000,000 and everything in between, #nanopore technology gives you the power to sequence any length fragment of DNA for all the insights you need. What you're missing matters. #wymm Find out more:

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Oxford Nanopore

@nanopore

10 months

From an initial sketch on the side of the road, to the only sequencing technology that provides native, real-time analysis of DNA & RNA fragments of any length, in fully scalable formats. Nanopore sequencing has come a long way: #TechTueasday

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Oxford Nanopore

@nanopore

6 years

We have launched MinIT, a powerful accessory for portable, real-time analysis of @nanopore DNA/RNA sequencing data. MinIT uses @NVIDIA GPU technology and can basecall 150k bases per second. Preconfigured with MinKNOW and EPI2ME. Read more: @NVIDIAEU #GTC18

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Oxford Nanopore

@nanopore

8 months

What’s more, telomere-to-telomere ( #t2t ) assemblies now achievable with JUST simplex. Q28 simplex data is accurate enough. You do not need data from any other platform — paving the way for @nanopore T2T assembly, using just simplex data. #nanoporeconf 1/2

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Oxford Nanopore

@nanopore

5 years

Today we've launched new '109' cDNA Kits enabling millions of whole transcripts to be sequenced end-to-end, in single reads: #cDNAseq

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Oxford Nanopore

@nanopore

4 years

Oxford Nanopore’s LamPORE test for the detection of the #SARSCoV2 virus (for #COVID19 ) now CE marked for in vitro diagnostic use on the GridION device. Read more:

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Oxford Nanopore

@nanopore

3 years

As DNA passes through a nanopore, its sequence is decoded in real time. Using adaptive sampling, it's possible to reject sequencing reads that are not of interest — leaving the nanopore available for your targeted region of interest: #TechTuesday

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Oxford Nanopore

@nanopore

9 months

Introducing TurBot. Our new sample-to-answer automated device. Register your interest here: #ASHG23 #WYMM

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Oxford Nanopore

@nanopore

8 years

A human genome on the portable MinION. 5 FlowCells: 11x coverage for $2750, 30x generated in total. #ashg16

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Oxford Nanopore

@nanopore

2 years

We are saying thanks and Happy Retirement to Jim, employee number 6!

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Oxford Nanopore

@nanopore

1 year

From an initial sketch on the side of the road, to the only sequencing technology that provides native, real-time analysis of DNA & RNA fragments of any length, in fully scalable formats. Nanopore sequencing has come a long way... Learn more:

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Oxford Nanopore

@nanopore

5 months

Excited to announce Mike Clark will showcase his improved FLAMES pipeline for single-cell RNA-seq analysis at #nanoporeconf . He'll discuss the advantage of the isoform-level quantification for accurate cell-typing, & new insight into neuron development.

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Oxford Nanopore

@nanopore

2 years

Last week we announced a new protocol explaining how to recover a DNA library mid-sequencing run. This protocol has been developed to enable precious samples to be recovered and transferred to a new flow cell for continued sequencing. Find out more here:

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Oxford Nanopore

@nanopore

1 year

Our latest platform software (MinKNOW) update supports end-to-end high-throughput projects. The update includes the integration of high-performance basecaller Dorado — to replace Guppy — for real-time, high-accuracy basecalling +methylation Read more: 1/5

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