Kerstin Göpfrich Profile Banner
Kerstin Göpfrich Profile
Kerstin Göpfrich

@KGoepfrich

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Professor @ZMBHh @UniHeidelberg & @mpi_mr_hd . We engineer a synthetic model cell from scratch with lipid vesicles and DNA/RNA origami-based molecular hardware.

Heidelberg
Joined October 2014
Don't wanna be here? Send us removal request.
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@KGoepfrich
Kerstin Göpfrich
1 month
What happens when you apply design principles from bottom-up synthetic biology to immunology? In Heidelberg and together with @FrischknechtLab @platten_michael & Oliver Fackler we compiled the prospects of bottom-up synthetic immunology @NatureNano
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@KGoepfrich
Kerstin Göpfrich
2 years
Finally I can share that we have been celebrating an ERC starting grant! A big thank you first and foremost to my excellent group and to everyone who supported us along the way. Excited for #SynCell work with ENSYNC!
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@KGoepfrich
Kerstin Göpfrich
2 years
We built DNA-based mimicks of cytoskeletal filaments capable of reversible assembly and cargo transport inside cell-sized compartments. Now out @NatureChemistry !
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@KGoepfrich
Kerstin Göpfrich
5 years
I guess that's me🤗It still feels like dreaming the best dream ever. Stay tuned for synthetic cells, DNA nanotech and microfluidics. And get in touch if you are interested in Master, PhD or postdoc projects in what will hopefully become a fun & productive group!
@mpi_mr_hd
Max Planck Institute for Medical Research
5 years
📢🥳We are super excited to announce that  @KGoepfrich  will head a Max Planck Research Group at our institute from now on! As you can see, her lab space is still in the making. 🚧😁  @maxplanckpress
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@KGoepfrich
Kerstin Göpfrich
2 years
Thank you all for the warm wishes and for the support!
@ZmbhH
ZMBH - Center for Molecular Biology Heidelberg
2 years
The ZMBH warmly welcomes Kerstin Goepfrich @KGoepfrich from @mpi_mr_hd as a new professor and research group leader. Her lab's research projects focus on biophysical engineering of life.
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@KGoepfrich
Kerstin Göpfrich
3 years
How can you build up structures on the inside of synthetic cells? With 3D laser printing. Very excited to share this work by @ToAbele et al @Cluster3DMM2O in Advanced Materials
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@KGoepfrich
Kerstin Göpfrich
3 years
Now @NatureComms : We realize a reaction pathway for synthetic cells that involves light-harvesting E. coli, pH-sensitive DNA origami and lipid vesicles
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@KGoepfrich
Kerstin Göpfrich
7 months
These beautiful DNA nanotube rings by @majaillig can actually contract! We start dreaming about an entirely synthetic division machinery for synthetic cells. Contraction mechanism with experiment, theory & simulation now out @NatureComms :
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@KGoepfrich
Kerstin Göpfrich
1 year
Thank you to an anonymous reviewer who recommended this book on the origins of life. Absolutely beautifully written, captivating and full of intersting thoughts.
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@KGoepfrich
Kerstin Göpfrich
4 years
Tips, tricks, tools and applications for the functionalization of cellular membranes with DNA nanotechnology - hope our new review @TrendsinBiotech is a useful resource: @CavalcantiAda
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@KGoepfrich
Kerstin Göpfrich
3 years
Now @NanoLetters : Light-triggered lipid peroxidation can increase the spontaneous curvature. That's how we divide DNA-containing giant unilamellar lipid vesicles 👇
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@KGoepfrich
Kerstin Göpfrich
4 years
We find that the choice of fluorophore can alter or completely inhibit dynamics of DNA structures. Now out @NAR_Open @KeJahnke @max_igaev @CompBioPhys
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@KGoepfrich
Kerstin Göpfrich
10 months
Happy 4th birthday to the group! Haven't quite reached the legal drinking age, but hey, it's Feuerzangenbowle. A big thank you to our academic family and friends, collaborators, supporters and, most importantly, all present and former members of the group @mpi_mr_hd and @ZmbhH
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@KGoepfrich
Kerstin Göpfrich
4 years
I applied 2 years ago and now I have my own group @mpi_mr_hd . Full independance, competitive salary and research funding, choice of over 80 host institutes. Happy to share my experience and to give advice!
@maxplanckpress
Max Planck Society
4 years
Call for Applications 2020/2021: We offer junior researchers again the possibility to apply for a position as a Max Planck Research Group Leader in all areas of science. Application deadline is October 22, 2020 #sciencecareer #MPRGL
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@KGoepfrich
Kerstin Göpfrich
4 years
Dividing christmas baubles (i.e. GUVs) and their regrowth - online just on time @angew_chem We divide phase-separated GUVs with enzymatic reactions or locally with light & describe the process with an analytical model. Congrats Yannik Dreher, @KeJahnke 🎄
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@KGoepfrich
Kerstin Göpfrich
4 years
WANTED: A #postdoc with experience in DNA origami or high-speed AFM, data analysis & a strong interest in synthetic biology. Join a friendly & motivated group @mpi_mr_hd @Cluster3DMM2O in Heidelberg. Happy to help with fellowship applications. Please RT!
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@KGoepfrich
Kerstin Göpfrich
4 years
Today is the 1st birthday of the group! Thanks @mpi_mr_hd for hosting us. Looking forward to the years to come.
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@KGoepfrich
Kerstin Göpfrich
4 years
Today a confocal microscope joined us on the mission to build a synthetic cell 🔬 Welcome to the team!
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@KGoepfrich
Kerstin Göpfrich
3 years
Accepted! Congratulations @KeJahnke et al. 🥳A joint efford involving @mpi_mr_hd @Cluster3DMM2O @mattertolife @ETH @UniHeidelberg
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@KGoepfrich
Kerstin Göpfrich
3 years
Our recent paper in a nutshell (uuuh, eggshell). Discovered on the breakfast table. Check out for the science behind the right image 🍳
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@KGoepfrich
Kerstin Göpfrich
8 months
We are looking to establish a DNA origami synthesis core facilty @UniHeidelberg . If worked with #DNAorigami in your PhD, have experience with chemical synthesis and good organizational skills, please get in touch! RT appreciated.
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@KGoepfrich
Kerstin Göpfrich
4 months
Why are we so exited about RNA origami? It could be a unique intermediate between DNA origami and proteins for the construction of synthetic cellular hardware. We design and encode an RNA cytoskeleton in synthetic cells: Feedback very welcome!
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@KGoepfrich
Kerstin Göpfrich
2 years
We all like to make functional structures from DNA origami. Here is a new function by Monari et al. Thanks @monari_luca !
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@KGoepfrich
Kerstin Göpfrich
5 months
We are looking for two #postdocs to join us: 1) @ERC_Research funded position in the context of RNA origami, cryoEM, synthetic cells, directed evolution; 2) A position in the excellence cluster @Cluster3DMM2O at the interface of chemistry & biology. Please share and get in touch!
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@KGoepfrich
Kerstin Göpfrich
8 months
Thrilled to announce that our initiative SynthImmune - engineering immune function with #SynBio - was selected for the excellence cluster competition @dfg_public ! Exciting science ahead with the best co-speakers Oliver Fackler & @michael_platten & colleagues @UniHeidelberg 🥳
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@KGoepfrich
Kerstin Göpfrich
1 year
Curious about the new world of RNA origami and why we are so excited about it? Check out our review Kudos to a number of excellent scientists in the field.
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@KGoepfrich
Kerstin Göpfrich
3 years
The credits for this go to my group! This is the time to say thank you to all current and former members of the team and to our friendly, supportive and collaborative academic family.
@DeLaporte_Lab
De Laporte Research Group
3 years
Congratulations to our 3 WIMA winners: @KGoepfrich , Jinghui Liu, and Shikha Dhiman! It was a true joy to see all this exciting, high quality research and a great way to build a nice network! Looking forward to the next WIMA Award 2022....
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@KGoepfrich
Kerstin Göpfrich
1 year
What a day! Congratulations to Yannik Dreher on handing in his PhD thesis. Soon it is time for defence No. 2! @UniHeidelberg @mpi_mr_hd @ZmbhH
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@KGoepfrich
Kerstin Göpfrich
3 months
Thank you very much @UniHeidelberg and @ZmbhH for the nomination and to all our mentors, collaborators and funders for their support over the years. This one goes to the group!
@UniHeidelberg
Uni Heidelberg
3 months
Förderpreis für Heidelberger Molekularbiologin: Kerstin Göpfrich erhält hochdotierte Auszeichnung der Alfried Krupp von Bohlen und Halbach-Stiftung @KGoepfrich @ZmbhH
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Kerstin Göpfrich
1 year
Ready for the PhD defence #2 tomorrow: @mpi_mr_hd shows itself in the best light. You will rock it, Yannik Dreher! 💪
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@KGoepfrich
Kerstin Göpfrich
1 year
Synthetic cells are on the move - quite literally: The Schwille @MPI_Biochem and Frey groups @LMU_Muenchen recently showed how mechanochemical feedback loops drive the persistent motion of liposomes. Here is my News & Views @NaturePhysics :
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@KGoepfrich
Kerstin Göpfrich
7 months
Two lessons on science communication from the COVID pandemic: 1) We should communicate science before it becomes emotional. 2) We have to reach a broad audience. In that sense big thank you to Apothekenumschau for writing about DNA origami and our work @SynthImmune !
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@KGoepfrich
Kerstin Göpfrich
4 years
Isn't it amazing that someone who is called "Do u dna" (i.e. make your DNA) wins the #nobelprize for editing DNA? Congratulations @doudna_lab !
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@KGoepfrich
Kerstin Göpfrich
1 year
Happy DNA Day everyone!! Keep smiling. Image: Laser printing of DNA hydrogels by @ToWalther .
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@KGoepfrich
Kerstin Göpfrich
2 years
The SynCell enthusiasts from Heidelberg @mpi_mr_hd . Thank you @SynCellEU for hosting us in The Hague and for the exciting programme!
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@KGoepfrich
Kerstin Göpfrich
5 years
We are online! Thanks @mpi_mr_hd .
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@KGoepfrich
Kerstin Göpfrich
1 year
Very grateful for #HFSP grant we received together with @tomo_matsuuraG and Dieter Braun @LMU_Muenchen .
@HFSP
HFSP
1 year
It's official! The 2023 #HFSP New Awardees are here! Congratulations to the 34 winning teams of #HFSPResearchGrants and the 52 researchers awarded #HFSPFellowships ! 🥳Are you a #2023HFSPAwardee ? 🏆Tell us! +info:
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@KGoepfrich
Kerstin Göpfrich
5 years
I am looking for a PhD student and a postdoc to join our brand new Biophysical Engineering Group @mpi_mr_hd in Heidelberg Interested in DNA origami and 3D printing for synthetic cells? Happy to chat at the #BiomembraneDays !
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@KGoepfrich
Kerstin Göpfrich
8 years
As a German living in the #UK I thank @zeitonline for the hashtag #WeLoveUKBecause !
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@KGoepfrich
Kerstin Göpfrich
4 years
#MaxSynBio2020 is taking place from Nov 30 to Dec 2. Hoping that a large and international bottom-up synthetic biology crowd can join us for this online meeting! @MaxSynBio @MaxPlanckBris @SynCellEU @buildacell @gasb_synbio Registrations are open & free.
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@KGoepfrich
Kerstin Göpfrich
2 years
To the successes of the last three years! Congrats @KeJahnke ! IF = %alc.
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@KGoepfrich
Kerstin Göpfrich
3 years
Happy & honoured to be one of them!
@mattertolife
Max Planck School Matter to Life
3 years
🥳We are excited to announce that eleven excellent scientists will join the #mattertolife faculty in October! Find out more on our homepage👉
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@KGoepfrich
Kerstin Göpfrich
3 months
Last year we met with about 60 scientists for 2 weeks to discuss what it means to synthesize life. Here is the summary of our discussion: We hope it represents diverse views and serves as a roadmap towards a big vision. Feedback welcome!
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@KGoepfrich
Kerstin Göpfrich
9 years
@NatureNews Following! #ShowUsYourScience : Folding #DNAorigami to make artificial channels in #lipid #membranes .
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@KGoepfrich
Kerstin Göpfrich
1 year
Undergrads: Interested in SynBio and in a 5-year Master-to-PhD programme at some of the best institutions in Germany (taught entirely in English)? Please apply! RT appreciated.
@mattertolife
Max Planck School Matter to Life
1 year
📣 You can now apply to the Max Planck School Matter to Life and join us in 2024! 🔥 Whether you apply to the MSc to PhD Direct Track Program or our ten-week paid research internships - we are looking forward to your application! (Deadline: 1 Dec, 2023)
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@KGoepfrich
Kerstin Göpfrich
3 months
Congratulations to @maiptran21 for winning the poster prize at #FDN2024 for her work on RNA origami. The group is proud of you🙌Thanks to the FDN crowd!
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@KGoepfrich
Kerstin Göpfrich
4 years
Our ( @KeJahnke @max_igaev @CompBioPhys ) preprint is online: With experiments & MD we show that one can shape the energy landscape for dynamic reconfiguration of DNA nanostructures without changing the DNA sequence. Feedback is very welcome!
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@KGoepfrich
Kerstin Göpfrich
3 years
Deeply sadened to hear that Ned Seeman passed away. He turned Esher's fish into DNA and us into DNA nanotechnologists. Thank you to a brilliant scientist for bringing a new field to life.
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@KGoepfrich
Kerstin Göpfrich
5 years
Single- and double-stranded DNA detected while skiing.
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@KGoepfrich
Kerstin Göpfrich
7 months
Want to lead a brand new DNA foundry in Heidelberg? Want to write the code for synthetic life? We are recruiting the head of the Carl Zeiss Synthetic DNA accelerator lab! Please RT, get in touch & apply now #SynBio 🧬👇
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@KGoepfrich
Kerstin Göpfrich
11 months
I recently had a nice and interesting conversation with Shane Farnsworth, happy to share it here @mattertolife @Cluster3DMM2O @SynthImmune @ZmbhH @mpi_mr_hd
@EscapedSapiens
Escaped Sapiens
11 months
Great conversation with @KGoepfrich about engineering artificial cells from scratch! We talk all things synthetic biology, from the challenges of building the various required components, to the ethics of potentially creating a whole new branch of life.
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@KGoepfrich
Kerstin Göpfrich
8 months
"The power lies in a big idea" - That's why creating life from non living building blocks should be a key focus of research in Europe. Thank you to the European Parliament for hosting us!
@SynCellEU
Synthetic Cell initiative
8 months
Thank you to Ivars Ijabs @ijabs and the European Parliament for hosting today's meeting, to all the participants, and to the speakers who have shown that Nature is our next #technology and that support is needed to accelerate #syncell #research and technological developments!
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@KGoepfrich
Kerstin Göpfrich
3 years
This work is truely amazing - I cannot recommend the paper enough. Big congratulations to Ken'ya Furuta and the entire team!
@NewsfromScience
News from Science
3 years
Much as a train switchyard can steer rail cars to different locations, researchers have engineered protein motors to carry tiny bits of cargo to different locations.
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@KGoepfrich
Kerstin Göpfrich
4 years
I had a joke about DNA origami, but it doesn't unfold well.
@Sciezgin
Erdinc Sezgin
4 years
I had a lipid raft joke, but I can't find it..
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@KGoepfrich
Kerstin Göpfrich
1 year
First part of our group retreat in Lausanne. Thank you @YSchaerli and @caiyizhi et al for a truly exciting meeting! #swissuksynbio Finally we also have a new group picture. 🙏
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@KGoepfrich
Kerstin Göpfrich
4 years
The best misspelling of my last name so far!
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@KGoepfrich
Kerstin Göpfrich
4 years
Interfacing DNA nanotech and actin networks: Light-triggered contaction breaks the symmetry. Congrats @KeJahnke ! @mpi_mr_hd @Cluster3DMM2O
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@KGoepfrich
Kerstin Göpfrich
2 years
We had some fun thinking about genotype-phenotype maps and reconstructing them with DNA origami. Now @BiophysJ :
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@KGoepfrich
Kerstin Göpfrich
1 year
What a day! Huge congratulations to Dr Dreher aka Dr GUVenator! Thanks to @graeter_mbm , Christine Selhuber-Unkel @MSE_UNIHD and Joachim Spatz and the whole BPE group for their support.
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@KGoepfrich
Kerstin Göpfrich
4 years
Thank you to the editors @Advintellsyst for selecting our article for Editor's Choice! @AdvSciNews
@KeJahnke
Kevin Jahnke
4 years
Our new paper is out: Actin-containing cell-sized droplets move autonomously due to Marangoni flows. We engineer their directed rotational and translational motility, which can persist for hours! @KGoepfrich @mpi_mr_hd @Cluster3DMM2O @AdvSciNews
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@KGoepfrich
Kerstin Göpfrich
2 years
Conquering complex engineered environments at #EngineeringLife2023 , including the route towards a synthetic cell 💪 Thank you to an amazing group of participants, to @Miapbp and of course to @BoekhovenLab and @WebersGroup !
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@KGoepfrich
Kerstin Göpfrich
3 years
We used this 👇to pull lipid nanotubes from vesicles and cells. Sometime nature's machines can do what we as biophysicists would normally do with AFMs or optical tweezers!
@mpi_mr_hd
Max Planck Institute for Medical Research
3 years
Tinsel for your christmas tree? 💫☄️ No, this is coordinated movement of actin filaments in a motility assay. @KeJahnke
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Kerstin Göpfrich
3 years
I am very proud of Kevin! Thank you for being brave enough to join a new lab as the first PhD student. And thanks for all the visible and invisible (!) support we received from @mpi_mr_hd @Cluster3DMM2O and collaborators.
@KeJahnke
Kevin Jahnke
3 years
I am very excited to have submitted my PhD thesis today! Thank you very much @KGoepfrich as well as all collaborators, colleagues and fantastic students for these exciting years! @mpi_mr_hd
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@KGoepfrich
Kerstin Göpfrich
2 years
Announcement of the day! @KeJahnke
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@KGoepfrich
Kerstin Göpfrich
3 years
Finally back in Cambridge after 2 years! @KeyserLab @DeptofPhysics
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@KGoepfrich
Kerstin Göpfrich
1 year
I am very happy and excited to see the support for life inspired molecular systems engineering in Heidelberg! Thanks to all the excellent colleagues who contributed to this success.
@UniHeidelberg
Uni Heidelberg
1 year
Neuer Forschungsbau für das Engineering von lebensinspirierten molekularen Systemen: Wissenschaftsrat hat Empfehlung für den Neubau ausgesprochen – Raum für innovatives Forschungsprogramm in den Ingenieurwissenschaften
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Kerstin Göpfrich
1 year
Dear MSc students, we have an awesome summer prgramme for you (lots of interesing connections if you are looking for a #PhD !) Apply by June, 20th Thank you to my colleagues @Cluster3DMM2O for putting this together. Please RT.
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@KGoepfrich
Kerstin Göpfrich
5 years
The group logo is in place. Soon we are ready to move into our new labs and offices @mpi_mr_hd 🧬
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@KGoepfrich
Kerstin Göpfrich
4 years
Cholesterol-tagged DNA self-assembles into polymersomes - at least for some types of polymers. For details see our new paper @AdvSciNews @mpi_mr_hd @Cluster3DMM2O
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@KGoepfrich
Kerstin Göpfrich
3 years
If a tree decides to behave like a liquid.
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@KGoepfrich
Kerstin Göpfrich
8 months
Exciting postdoc grant! In close collaboration with @EllenbergLab @EMBLHeidelberg we want to remodel nuclear membranes with RNA origami Funded by @ResearchLifesci Please get in touch if you are interested!
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@KGoepfrich
Kerstin Göpfrich
5 years
It is a great honour to introduce my first PhD student and founding member of the Biophysical Engineering group @mpi_mr_hd : @KeJahnke . He is building dynamic systems with DNA nanotechnology and microfluidics. Follow him for updates from our group (and pretty microscope images)!
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@KGoepfrich
Kerstin Göpfrich
4 years
I thought I prepared a surprise for my grandparents diamond wedding – used a deep learning tool to convert their black-and-white wedding pics into full color 👰‍♂️🤵‍♂️My grandfather’s reaction: Oh yes, I know, I did the same for our family tree 😬 Not quite what I expected...
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@KGoepfrich
Kerstin Göpfrich
7 years
Wow - the @nanopore DNA sequencer costs less than the new iPhone! A sequencer for Christmas anyone?
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@KGoepfrich
Kerstin Göpfrich
2 years
We certainly had fun!
@mpi_mr_hd
Max Planck Institute for Medical Research
2 years
We are counting the days until the 75th anniversary of the founding of the Max Planck Society @maxplanckpress 🎊 That's why we are browsing through the history of our own institute. What do you think: Did @KGoepfrich 's group do a good job in recreating this historical image?👩‍🔬📽️
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Kerstin Göpfrich
2 years
I am sad and at the same time very proud to see the first PhD student leave the group. A big thank you and all the best for your future Dr. @KeJahnke !
@KeJahnke
Kevin Jahnke
2 years
I am thrilled to announce that as of next week I will be joining the Weitz Lab @Harvard for my postdoc! Looking forward to start a new adventure in this interdisciplinary and exceptional research environment
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@KGoepfrich
Kerstin Göpfrich
3 years
Thank you! I am excited to be part of the Hector Fellow Academy and to kick-start a new project on synthetic cells.🧬
@mpi_mr_hd
Max Planck Institute for Medical Research
3 years
🥳Congratulations to our group leader @KGoepfrich on being elected as a Hector Research Career Development Awardee by the Hector Fellow Academy!
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@KGoepfrich
Kerstin Göpfrich
3 years
Happy to hear that my reviewing was helpful. More importantly: Hope the authors see it in the same way.
@CommsChem
Communications Chemistry
3 years
We'd like to thank and acknowledge @KGoepfrich for exceptional contributions to peer review. Congrats Dr Kerstin Göpfrich on being our first 2022 reviewer of the month!
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@KGoepfrich
Kerstin Göpfrich
4 years
I quite like the view from my new office. Thank you @mpi_mr_hd !
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@KGoepfrich
Kerstin Göpfrich
1 year
Fantastic talk by @CavalcantiAda at #EBSA2023 on receptor-mediated regulation of cell mechanics. Here are the references for our collaboration on the DNA nanotech tools if you want to give them a try:
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@KGoepfrich
Kerstin Göpfrich
4 years
Yes! Let's spread the passion for science but not the virus 🤩 Thanks @mattertolife !
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@KGoepfrich
Kerstin Göpfrich
5 years
Now @NanoLetters : We actuate plasmonic nanostructures in microfluidic compartments A collaboration between @mpi_mr_hd and @MPI_IS , feat. @M_J_Urban , Christoph Frey, Ilia Platzman, Joachim Spatz and Na Liu @UniHeidelberg @mattertolife
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@KGoepfrich
Kerstin Göpfrich
9 years
Out of all the things you could #crochet : Why not a petri dish full of #bacteria ?
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@KGoepfrich
Kerstin Göpfrich
5 years
Today's task: Making new DNA origami @mr_mpi . Each drop contains a different DNA sequence, together they assemble into a nanoscale cube.
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@KGoepfrich
Kerstin Göpfrich
4 years
We liked the video, so we just printed it! @AdvSciNews @zeiss_micro
@mpi_mr_hd
Max Planck Institute for Medical Research
4 years
A flip book showing a paper in a nutshell. 🤩 @KGoepfrich and @KeJahnke are getting creative!
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Kerstin Göpfrich
4 years
We have a new group member @Cluster3DMM2O ! Thank you @zellmechanik for the fun visit, the excellent training and the setup of course.
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Kerstin Göpfrich
3 years
Today, Heidelberg, Starkregen. Yes, we did promise that Heidelberg was nice and sunny, @schroep . I am starting to miss the UK drizzle!
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Kerstin Göpfrich
8 months
Synthetic biology aims to tackle disease and give cells superpowers Thank you @KatieKrypton for writing about our work and our vision to build a cell from skratch!
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Kerstin Göpfrich
2 years
Beautiful cover of Ned Seeman's vision of DNA crystals. It is an honor to contribute to the special issue @BiophysJ dedicated to a brilliant scientist with our DNA origami polyominos
@DNA_Nanotech
Yoel Ohayon
2 years
In Memory of Ned Seeman
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Kerstin Göpfrich
5 years
Interested in 3D printing, DNA origami and synthetic cells? Apply for a fully funded PhD position in my group in Heidelberg! More info:
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