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John P. Leonard, MD Profile
John P. Leonard, MD

@JohnPLeonardMD

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Doctor for lymphoma patients, researcher, collaborator, professor/senior associate dean @WeillCornell & @NYPhospital Tweets mine RT not=endorsement, he/him/his

Weill Cornell Medicine
Joined November 2014
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Here is the big #hairstylesforheroes "reveal" - Nearly $75,000 raised to support the efforts our front line care team! Thanks to all who have supported and not too late to donate! Lots of great looks! #WCMDeptofMed @WeillCornell
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@JohnPLeonardMD
John P. Leonard, MD
3 years
A lymphoma version of "scientific papers" with apologies to and acknowledgment of @xkcdComic
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@JohnPLeonardMD
John P. Leonard, MD
6 years
I prefer more slides with less data per slide rather than fewer slides jam packed with multiple miniscule figures #ASH18
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@JohnPLeonardMD
John P. Leonard, MD
2 years
Lots of “first class” hematologists sitting in coach! #ASH22 @ASH_hematology
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@JohnPLeonardMD
John P. Leonard, MD
4 years
This says a lot......
@aphillippy
Adam Phillippy
4 years
Throwback to 5 years ago when Tony Fauci, at 74 yo, was suiting up to treat an Ebola patient himself because he "wanted to show his staff that he wouldn't ask them to do anything he wouldn't do himself". This is what leadership looks like.
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@JohnPLeonardMD
John P. Leonard, MD
3 years
You can learn far more about clinical research (and help patients more) by designing, conducting and analyzing clinical trials than you do by reading (or posting) tweets about them
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@JohnPLeonardMD
John P. Leonard, MD
4 years
7 pm on York Avenue between 68 and 70th street in NYC.....2/3 of the people on the street are nurses reporting for their shift @nyphospital @WeillCornell - much appreciation and admiration....
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Rather than a power nap pod, I think I would prefer being able to get a banana or coffee without a long line...I know a few NYC street vendors who could resolve this very well.... #ASH19
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@JohnPLeonardMD
John P. Leonard, MD
6 years
I have admiration for #ASH18 speakers who are presenting in their non-native language (English) - for some no doubt not easy but important contributions to the meeting
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@JohnPLeonardMD
John P. Leonard, MD
5 years
“Why is it that most of those who are successful think it is all their doing” - great discussion ⁦ @PreetBharara ⁩ that touches many aspects of our society and politics
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@JohnPLeonardMD
John P. Leonard, MD
3 years
For immunocompromised individuals getting a 3rd "booster" COVID vaccine: DO NOT ASSUME that the "booster" necessarily solves potential problem of lower immunity against COVID (it doesn't for many) - need to speak w/your MD/team and often mask, distance etc - no false reassurance!
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@JohnPLeonardMD
John P. Leonard, MD
4 years
A good rule of thumb is to pay attention to the doctor who has more patients with than tweets about a disease....
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Outstanding omelet station at the buffet at my #ASH20 breakfast meeting location - will come back tomorrow! #ASHFromHome
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@JohnPLeonardMD
John P. Leonard, MD
4 years
My new zoom avatar #hairstylesforheroes
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Spent the beginning & end of a long day thinking about a longtime patient who died overnight - he taught & mentored many disadvantaged students & had a remarkable way of telling me on most visits that by helping him we were impacting many lives - a special man who will be missed
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@JohnPLeonardMD
John P. Leonard, MD
2 years
A patient memorialized one of my frequent expressions
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Patient comes for second opinion with one lymphoma diagnosis rendered previously. Sees our team, diagnosed with another subtype with entirely different prognosis and less aggressive therapy needed. Expert #lymphoma pathologist review so important!
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Patient with new lymphoma, trying to get a PET scan to stage…….insurance representative (deciding on precertification for scan): “What stage is it?”…..Great question, wish I knew!
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@JohnPLeonardMD
John P. Leonard, MD
5 years
My patient of 13 years says he has a PhD in Mantle Cell #lymphoma ....I think he is right—-guess that makes me his dissertation advisor
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@JohnPLeonardMD
John P. Leonard, MD
7 years
I expect MDs to spend much more time explaining to #lymphoma patients why they are not CAR-T candidates than managing the very few who are
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@JohnPLeonardMD
John P. Leonard, MD
3 years
The #ASH21 #LeonardList high impact #lymphoma abstract finalists
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@JohnPLeonardMD
John P. Leonard, MD
6 years
We offer our patients innovative, state-of-the-art therapies - but sometimes just pulling up a chair and having a good talk is what can make the greatest impact
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@JohnPLeonardMD
John P. Leonard, MD
3 years
If you are immunocompromised or otherwise high risk, right now it seems best to “hunker down” as best you can. Having unmasked contact with people with recent “negative” tests still has some risk as things can evolve….
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@JohnPLeonardMD
John P. Leonard, MD
3 years
One of the most important things about work is working with good people
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@JohnPLeonardMD
John P. Leonard, MD
4 years
I have said to many patients over the years that while you may miss/modify one important family holiday (e.g. being in the hospital) it is with the goal of sharing many more in the future....seems like similar approach very relevant now for many of us....
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Those who participate in clinical trials are heroes
@matthewherper
Matthew Herper
3 years
Bill Ludwig, patient who helped pioneer cancer immunotherapy at Penn, dies at 75 of COVID-19
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@JohnPLeonardMD
John P. Leonard, MD
3 years
State laws restricting out of state video visits without licensure are absurd and frankly abusive to patients - at a point where some patients want to drive out of their home state to do a video visit from their car in a parking lot in another location where it is “legal”….
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@JohnPLeonardMD
John P. Leonard, MD
1 year
Very proud of our former chief resident..and all of our residents….⁦ @WeillCornell ⁩ ⁦ @nyphospital
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Two patients meeting in clinic for first time - one local, one lives several states away - patient 1 offers to have patient 2 stay at her house to ease the burden - amazing how patients come together to try to help each other through things
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@JohnPLeonardMD
John P. Leonard, MD
4 years
If she can fill out her ballot while getting a chemotherapy infusion WE have no excuses - VOTE!
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@JohnPLeonardMD
John P. Leonard, MD
4 years
I treat patients with #lymphoma . There are several FDA-approved drugs for lymphoma that I have never treated a patient with, & some others I have rarely used. That said, I am glad that they ALL are available if/when my patients and I - together - decide they are a good option.
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Patient with mantle cell #lymphoma .....over 12 year history, 2 lines of treatment on trials, doing well....never has had chemotherapy....the world is changing....
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Why does a twitter chat need a pharma sponsor?
@MDedgeHemOnc
MDedge Hematology & Oncology
5 years
Sponsored: Join us for a Twitter chat on #CLL during #ASH19 on Dec. 10th at 6 PM EST with @anthonymatomd and @chadinabhan on #MDedgeChats .
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@JohnPLeonardMD
John P. Leonard, MD
6 years
The terms “shows promise” and “promising” in regard to a new drug or treatment regimen are non-scientific and frankly useless. Real advances don’t need to be described in this way, the data tell the story.
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@JohnPLeonardMD
John P. Leonard, MD
6 years
With respect to hard work of all involved in these lymphoma CAR-T studies, and importance of data to the community, if they going to be presented over and over at every meeting there should be a clear description of what is new/incremental info and time frame that is new #ASCO18
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Just recorded the #ASH19 #LeonardList edition of our ⁦ @WeillCornell #CancerCast podcast highlighting 10 key #lymphoma abstracts - next week the episode (with my commentary on these + 5 bonus extra pod-only abstracts) will drop and the 10 day twitter countdown will begin!
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@JohnPLeonardMD
John P. Leonard, MD
2 years
Back from speaking at the Haematology Association of Ireland meeting - great people, scenery, history….and Guinness
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Is there an ICD 10 code for “Questions prompted by New York Times article” ?
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@JohnPLeonardMD
John P. Leonard, MD
5 years
“When 90% of #lymphoma are not ‘Hodgkin’ ...why do we call them ‘non-Hodgkin’? Maybe we should change the name....” - B Cheson
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@JohnPLeonardMD
John P. Leonard, MD
8 years
Why we do what we do
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@JohnPLeonardMD
John P. Leonard, MD
2 years
Seems like a higher percentage of the people in the room at the start of the #lymphoma #CLL session at #ASCO22 could have stayed in the room to hear the presentations on the important issue of healthcare disparities in these conditions
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Fun
@WCMEnglanderIPM
WCM Englander Institute for Precision Medicine
4 years
Please join us in congratulating @EngIPM Member John. P. Leonard, M.D. ( @JohnPLeonardMD ) on his appointment today as Senior Associate Dean for Innovation and Initiatives @WeillCornell ! #CancerResearch #PrecisionMedicine
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Just saw a mantle cell lymphoma patient diagnosed 10 years ago - still in remission from our initial therapy on a clinical trial...he and his wife reminisced about all (good) that has happened in their life during that time...
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@JohnPLeonardMD
John P. Leonard, MD
3 years
The #ASH21 #LeonardList high impact #lymphoma abstract list is finalized & under tight security (my backpack)! Countdown daily 12/1 to 12/10 or listen to the #cancercast podcast review (with 5 extra bonus selections) recorded & expected to drop on 12/1.
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@JohnPLeonardMD
John P. Leonard, MD
3 years
The #ASH21 #LeonardList high impact #lymphoma abstract finalists
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Great to have 2 daughters, in college in different cities, both marching in #WomensMarch2018
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@JohnPLeonardMD
John P. Leonard, MD
6 years
A patient brings us fresh-picked blueberries, my physician assistant turns them into muffins, I eat - we are truly a multidisciplinary collaborative team in our clinic (excuse my purple fingers)
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@JohnPLeonardMD
John P. Leonard, MD
7 years
Just went upstairs and saw my #lymphoma patient's newborn baby - a good day @nyphospital @WeillCornell
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Patient with recurrent follicular lymphoma doing well on current treatment: “Maybe I should have had this back at the beginning” - the drug hadn’t yet been developed 15 years ago when she was diagnosed - shows the benefits of progress we are making!
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Think about the fact that despite the flaws of the US Postal Service, any person can - for 55 cents - have an envelope and contents delivered across the country a few days later door to door. This is impressive, important and should be protected and not messed around with.
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@JohnPLeonardMD
John P. Leonard, MD
2 years
Today I had to tell 2 patients requesting a telemedicine consult that I am unable because I am not licensed in their home states. And this is good why???
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Over 100 #ASH19 @ASH_hematology abstracts identified by keyword search “real world” - are the others from the “unreal world” ? And do abstracts from authors working at major academic referral centers and pharma companies represent the “real world”?
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@JohnPLeonardMD
John P. Leonard, MD
4 years
“There cannot be greater rudeness than to interrupt another in the current of his discourse.” - John Locke
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@JohnPLeonardMD
John P. Leonard, MD
3 years
After about 20 years of work in “cell of origin directed” strategies in upfront and relapsed DLBCL #lymphoma it seems like the newest advances are “cell of origin agnostic” - there are important lessons here….
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@JohnPLeonardMD
John P. Leonard, MD
6 years
As a community in lymphoma, we should be embarrassed by the lack/limitations of quality of life data available on treatments - it is pretty sad that we cannot currently provide solid data to guide choices - we need to do better and collaborate w experts with novel tools #ASCO18
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Intrathecal prophylaxis in DLBCL #lymphoma seems to treat the doctor's worries more than the patient's risk of CNS relapse.....
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Those who care about progress for patients and advances in treatment need to be aware of the staffing challenges in clinical research programs across the country - that can be marginally funded in the best of times - multiple strategies needed to support studies of new therapies
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@JohnPLeonardMD
John P. Leonard, MD
1 year
Dr. Peter Martin “ketching up” in clinic
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Diffuse large B cell #lymphoma therapy is improving (and getting more complicated)! Clinical trials are the engine! Greater participation and faster enrollment are the keys to rapid progress and saving/improving more lives! #ASH21
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@JohnPLeonardMD
John P. Leonard, MD
5 years
My editorial comments in @JCO_ASCO on the PHOENIX study of Ibrutinib + R-CHOP in Diffuse Large B Cell #Lymphoma :De-Cell-eration in Therapy for Diffuse Large B-Cell Lymphoma | Journal of Clinical Oncology
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@JohnPLeonardMD
John P. Leonard, MD
4 years
So the CAR-T debate of which works better/is less toxic is now going to be rivaled by the bispecific antibody debate of which works better/is less toxic.... #ASH20
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@JohnPLeonardMD
John P. Leonard, MD
4 years
It’s very easy to criticize a clinical trial’s design when you know the results
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Kudos to everyone who did the hard work (and the patients who participated) for the studies to be presented at #ASH21 - most importantly to advance knowledge and patient care - participating in research is the way to improve outcomes
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Six new physicians recently added to the Heme/Med Onc team @WeillCornell @nyphospital - we are growing and expanding our clinical and research programs under @DrMhidalgo - exciting progress!
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Key point-for clinical trials in follicular & DLBCL #lymphoma there is NO NEED to do BM biopsies to assess response! Changes response in <1% of enrolled pts. Lets do patient friendly trials & do BM bx only if needed for valid clinical/correl science reasons! #LeonardList #ASH18
@JohnPLeonardMD
John P. Leonard, MD
6 years
Now for #LeonardList key #ASH18 #lymphoma abstract number 8 - 1605 Rutherford @drsarahruth - Bone marrow biopsies do not meaningfully change response assessments in follicular and DLBCL #lymphoma clinical trials (from GALLIUM and GOYA studies) w/2600 pts
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@JohnPLeonardMD
John P. Leonard, MD
2 years
Remembering a special person and close colleague with a new lectureship @weillcornell @WCMLymphoma
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Happy to see a follicular #lymphoma patient today in clinic who I have cared for over 20 years (since I was a brand new attending)! Made us both feel old, but both aiming for the next 20 plus years!
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@JohnPLeonardMD
John P. Leonard, MD
4 years
If a doctor can have a serious conversation with a patient and family through 2 masks and a face shield, a football coach can keep his cloth mask up to scream at a referee...
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Pretty soon we should be comparing bispecific ab (alone or in combo) randomized vs CAR-T (w/crossover) in a number of #lymphoma settings….though I expect biases (in both directions) may preclude such depending on the situation #ASH21
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@JohnPLeonardMD
John P. Leonard, MD
3 years
One of the best things about an in person scientific meeting is being able to turn to insightful and respected colleagues nearby and ask “what do you think of that study?” - here’s hoping for a healthy dose of those exchanges in some form at #ASH21
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@JohnPLeonardMD
John P. Leonard, MD
8 years
Unless it is a "parachutes and planes" single arm trial you probably should not claim you improved survival w/o control arm #ASH16
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Big day today ⁦ @WeillCornell
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Regardless of my haircut, I #MaskUp to protect my patients, colleagues, family & friends, & myself. This is especially important to all of us at @WeillCornell @nyphospital I challenge @BrendonStilesMD @mdmanishshah @DrMhidalgo @drallysonocean @FeliceSchnoll to show their masks
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Black Friday: The annual day when hematologists overwhelm barbershops and hair salons to get their pre #ASH18 haircuts (ok it may extend over a few days but lots get pre-ASH cuts - see if you can guess at the meeting....)
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@JohnPLeonardMD
John P. Leonard, MD
6 years
So we had the pre- #ASH18 haircut, the busy meeting, and now the cycle continues with.... wait for it....the post-ASH respiratory virus (fostered by air travel) ....no doubt there are plenty of them out there...or coming soon...🙁 @ASH_hematology
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@JohnPLeonardMD
John P. Leonard, MD
5 years
Patients are sick of hearing about, thinking about, worrying about and dealing with concerns about measles. It is ridiculous that we are at this point. Totally avoidable. The amount of energy that has had to be devoted to this issue could be better spent on many other things.
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Seeing a patient in mid 80s who I have followed (never treated) for 2 years (over 9 visits) with an asymptomatic DLBCL that hasn't progressed (she smartly declined rx). Me: "See you in 6 months" Her: "If you don't see me it means I died" So much to learn from this encounter....
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@JohnPLeonardMD
John P. Leonard, MD
4 years
I had a headache this am. Took ibuprofen. I know it has possible side effects, sometimes serious. My headache got better. Not sure if it was due to the ibuprofen or if it would have gotten better anyway. No OS benefit. No formal QOL analysis. I’m glad ibuprofen is available.
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Seems unlikely every B cell lymphoma patient will ultimately get a CAR-T, but seems more likely that every B cell lymphoma patient will get a bispecific antibody..... #ASH20
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Tomorrow begins #LeonardList twitter countdown of 10 top #ASH18 lymphoma abstracts - BUT anyone wanting to hear my comments on the full #LeonardList (+ 5 podcast-only bonus picks) they are now live on #CancerCast - feedback welcome via twitter #LeonardList
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Despite our challenges, frustrations, disappointments and anger - it is important to keep in mind that there are a lot of people working hard in different ways to make the world better - and lots of opportunities for all of us to do so - big and small
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@JohnPLeonardMD
John P. Leonard, MD
4 years
“A coward is incapable of exhibiting love; it is the prerogative of the brave.” - Mahatma Gandhi
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Over 25 years after the important publication by Margaret Shipp and colleagues of the International Prognostic Index (IPI), we now have reached a point where we will treat Diffuse Large B Cell #lymphoma patients differently based on their IPI scores #ASH21
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@JohnPLeonardMD
John P. Leonard, MD
4 years
I need a haircut! We’re launching the #HairstylesForHeroes campaign to support #WCMDeptOfMed junior faculty & trainees. I’ll sport a crazy hairstyle (? mullet, mohawk, dye) once we meet our fundraising goal. Donate & help spread awareness. #TogetherWithWCM
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@JohnPLeonardMD
John P. Leonard, MD
4 years
The first step is to achieve a remission. The next goal is then to reach a cure.
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Medicine is a science of uncertainty and an art of probability. — Sir William Osler
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@JohnPLeonardMD
John P. Leonard, MD
6 years
The “lymphoman water bottle” - wish I’d thought of it!
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Glad to see we are removing requirements for bone marrow biopsy in many #lymphoma clinical trials! Usually not essential and more patient-friendly!
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@JohnPLeonardMD
John P. Leonard, MD
3 years
Whether virtual or in person, have to do the pre #ASH21 haircut
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@JohnPLeonardMD
John P. Leonard, MD
4 years
It is wonderful to hear an inspiring speech from a leader you can respect, believe and have pride in
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@JohnPLeonardMD
John P. Leonard, MD
1 year
The Fauci Selfie
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@JohnPLeonardMD
John P. Leonard, MD
6 years
Would be reasonable to run randomized or pragmatic trial of now standard EHR (eg Epic) vs streamlined version w less detail (fewer checkboxes largely for billing) w/endpoints of clinical outcomes, patient satisfaction & MD/RN/provider QOL @cuttingforstone
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Remember my first day as intern/on call night. 30 yrs ago today. To my resident’s horror I “renewed” my patients’ orders by d/cing every medication & reordered them all. Thought was the way to do it. That night I lost my papers w/everyone’s sign out info. Days of the giants.
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@JohnPLeonardMD
John P. Leonard, MD
4 years
Just finalized the #ASH20 #LeonardList of top 10 #lymphoma abstracts - lots of great studies - daily annual countdown starts wednesday & we just recorded #Cancercast podcast to post soon with 5 additional bonus selections & my comments. Looking forward to feedback and dialogue!
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@JohnPLeonardMD
John P. Leonard, MD
3 years
In clinic today post #ASH21 - what is crystal clear on new data on diffuse large B cell #lymphoma is that often choice not "crystal clear" - pts don't fit into neat boxes/algorithms - good care requires a patient-centered discussion & wisdom in applying data to individuals
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