First-line treatment of patients with pemphigus with the Ritux 3 regimen was associated with long-term complete remission without corticosteroid therapy without any additional maintenance infusion of rituximab.
Infection of the nails by fungus is called onychomycosis. This Patient Page describes the risk factors, clinical features, diagnosis, and treatment of onychomycosis.
Dermatomyositis (DM) is a condition affecting the skin (dermato) and muscles (myositis). This Patient Page describes the symptoms, diagnosis, and treatment of dermatomyositis.
Traction
#alopecia
is a form of hair loss caused by prolonged or repetitive tension on the hair due to tight braids, locks, and other hairstyles. This JAMA Dermatology Patient Page discusses the diagnosis and treatment of traction alopecia.
Low-dose oral minoxidil (5 mg per day) had similar efficacy to topical minoxidil, 5%, for men with androgenetic alopecia and can be an option for patients who prefer oral therapy or are intolerant to topical treatment.
Trichophyton indotineae is a recently-emerged fungus causing severe cases of ringworm across the world that often fail first-line therapy. This paper provides comprehensive analyses of the largest United States cohort of Trichophyton indotineae infections.
A 24-year-old woman presented to her primary care physician with a 1-month history of nonproductive cough and shortness of breath followed by 2 weeks of fevers, chills, night sweats, and left neck pain and swelling.
Case report: a 6-year-old girl who presented with symmetrical massive keratotic plaques on the palms, soles, and perioral area, as well as hair loss for 4 years.
Alopecia areata (AA) is a type of hair loss disorder caused by the immune system.
This Patient Page describes the symptoms, diagnosis, and treatment of alopecia areata.
Alopecia areata (AA) is a type of hair loss disorder caused by the immune system.
This Patient Page describes the symptoms, diagnosis, and treatment of alopecia areata.
Drug reaction with eosinophilia affects adults and children and can be associated with harm or even death. It usually occurs 2 to 8 weeks after beginning to take a medication.
Upadacitinib demonstrated superior and more rapid skin clearance and itch relief with tolerable safety compared with dupilumab in patients with moderate-to-severe atopic dermatitis
This case report describes well-defined, polycyclic, and geographic hyperkeratotic plaques that involved the axillae, chest, flanks, inguinal folds, and buttocks.
This case report describes numerous warm, red, edematous, tender, fluctuant, and purulent draining nodules on the abdomen following a catgut implant procedure.
Study findings highlight that rituximab combined with omalizumab is well tolerated, may improve outcomes in patients with refractory bullous pemphigoid who are unresponsive to rituximab monotherapy, and may accelerate time to remission.
Itraconazole is highly efficacious at all 3 doses but requires prolonged treatment, and a substantial number of patients relapsed after successful treatment.
#Research
During the first few months of life, once-weekly pulsed dye laser treatments for port-wine birthmark are associated with improved therapeutic outcomes and shorter overall treatment duration.
Most patients with VEXAS syndrome exhibit skin involvement, and skin disease often manifests early in the disease course, underscoring the pivotal role of early dermatologic diagnosis.
Prurigo pigmentosa’s clinical features, particularly hyperpigmentation of lesions, may partly depend on the patient’s ethnic origin, thus, this could lead to underdiagnosis of prurigo pigmentosa among dermatologists beyond Asia.
Case report: multiple solitary open black comedones located bilaterally on the malar cheeks and temples as well as yellowish, smooth-surfaced papulonodular lesions in close association with the comedones.
A nonrandomized clinical trial showed that oral abrocitinib 200 mg daily may be effective and well tolerated in the treatment of adults with prurigo nodularis and chronic pruritus of unknown origin.
A 38-year-old man presented with numerous pink-yellow firm papules and nodules on the bilateral elbows for 10 years spreading to the hands and knees in the past year. What is your diagnosis?
This case report describes a patient in her 30s who was born with ichthyosis who presented with plate-like scale that covered her whole body as well as ectropion.
Homogenous brown patterns are predominant in patients of both cardiofaciocutaneous syndrome (CFC) and Costello syndrome, with nevi from CFC patients having a slight tendency towards disorganized patterns.
BAP1 TPDS was associated with a high rate of nail abnormalities consistent with onychopapillomas in adult carriers. Findings suggest that multiple onychopapillomas may be a novel cutaneous diagnostic sign in adults with BAP1 TPDS.
A man in his 60s presented with a 5-year history of diffuse erythematous, edematous annular plaques, low-grade fevers, and mild leukopenia. What is your diagnosis?
This case report describes well-defined, polycyclic, and geographic hyperkeratotic plaques that involved the axillae, chest, flanks, inguinal folds, and buttocks.
A woman in her 30s with myasthenia gravis diagnosed at age 27 years presented to the emergency department with severe erythroderma over the past 2 months. What is your diagnosis?
Case report describes a woman in her 30s who presented with cutaneous lesions since age of 2 to 3 years with erythema and pain on her nose, both cheeks, and ears when exposed to cold temperatures that progressed to nasal and auricular cartilage necrosis.
Restriction of dietary sodium intake may be a cost-effective and low-risk intervention for atopic dermatitis, suggests study of adults from
@uk_biobank
.
Medical treatment of moderate hidradenitis is:
1. Tetracycline 500 mg bid OR doxycycline + minocycline 50-100 mg bid for 12 weeks
2. Clindamycin + rifampicin 300 mg bid each for 10 weeks
3. Adalimumab OR Infliximab OR dapsone OR acitretin
A woman in her 60s presents with a pruritic rash that initially developed on the legs and progressed to her feet, arms, hands, and trunk, with associated symptoms of a burning sensation and occasional pain. What is your diagnosis?
Study findings highlight that rituximab combined with omalizumab is well tolerated, may improve outcomes in patients with refractory bullous pemphigoid who are unresponsive to rituximab monotherapy, and may accelerate time to remission.
A woman in her 80s presented with erythematous, nondesquamative, annular plaques in a cluster of jewels pattern on her wrists and legs. What is your diagnosis?
This case report describes the clinical course of a 32-year-old woman with anti-synthetase syndrome presenting with angioedema-like panniculitis and subsequently cutaneous ulcers, synovitis, and fevers, found to have a clonal TCR-beta gene rearrangement.
Case report: a man in his 40s who presented with a 5-month history of recurrent pruritic papular erythema with mild scaling on the face, left forearm, and groin.
This case report describes a woman in her 20s with painful, red skin lesions present for 6 months that had gradually progressed from the groin to other sites.
Case report describes nonblanching, confluent, purpuric macules and patches on the palmoplantar and dorsal finger surfaces and red to grayish papulovesicles on the dorsal hands and feet, limbs, trunk, and face.
Pseudofolliculitis barbae (PFB), also called razor, shaving, or barber’s bumps, occurs when hairs curve back and re-enter or grow under the skin after shaving. This Patient Page describes the symptoms, diagnosis and testing, and treatment of PFB.
Osler nodes and Janeway lesions are considered classical findings of infectious endocarditis. However, they are present in only about 2.7% and 1.6% of cases, respectively. This case report describes Osler nodes and Janeway lesions on a man in his 70s.
Most viewed in the last 7 days from
@JAMADerm
:
Is oral minoxidil effective in treating androgenetic alopecia in men compared with topical minoxidil, 5%?
A man in his 30s presented with a progressively necrotic plaque on the nose, scattered nodules on the extremities, and erythematous papules on the arms and legs. What is your diagnosis?
As dermatologists responsible for the cutaneous health of all patients, delivering high-quality care to people with disabilities is a duty and a privilege
Case report: recurrent episodes of pruritic vesicular lesions and erosions on the face and photoexposed areas of the arms as well as multiple varioliform scars.
Case report: a man in his 40s who presented with a 5-month history of recurrent pruritic papular erythema with mild scaling on the face, left forearm, and groin.
Case report: a 6-year-old girl who presented with symmetrical massive keratotic plaques on the palms, soles, and perioral area, as well as hair loss for 4 years.
A man in his 20s presented to the dermatology department with a monthlong history of gradually progressing papules and nodules on the face, accompanied by fever, fatigue, and weight loss. What is your diagnosis?
Medical treatment of moderate hidradenitis is:
1. Tetracycline 500 mg bid OR doxycycline + minocycline 50-100 mg bid for 12 weeks
2. Clindamycin + rifampicin 300 mg bid each for 10 weeks
3. Adalimumab OR Infliximab OR dapsone OR acitretin
Most patients with VEXAS syndrome exhibit skin involvement, and skin disease often manifests early in the disease course, underscoring the pivotal role of early dermatologic diagnosis.
A woman in her 70s presented with painless, rapidly progressive, edematous, necrotic papules and plaques on the extremities, buttocks, and face. What is your diagnosis?
A man in his 60s presented with a truncal rash consisting of concentric annular red plaques with fine scale. Based on the clinical images and histopathology, what is the diagnosis?
@LeahSwansonMD
Case report: facial atrophic papules with telangiectasias, streaked hypopigmented and hyperpigmented papules on the left side of the trunk and extremities, and soft yellow fat herniations.
Drug reaction with eosinophilia affects adults and children and can be associated with harm or even death. It usually occurs 2 to 8 weeks after beginning to take a medication.
Case report: well-demarcated brown plaques with overlying fine scale in the bilateral axillae, inframammary folds, and inguinal folds and widespread coral-red fluorescence.
Cellulitis is a common infection of the deep layers of the skin, commonly caused by bacteria called
#Staphylococcus
or
#Streptococcus
. This Patient Page describes the symptoms, possible causes, and treatment of
#cellulitis
Cellulitis is a common infection of the deep layers of the skin, commonly caused by bacteria called
#Staphylococcus
or
#Streptococcus
. This Patient Page describes the symptoms, possible causes, and treatment of
#cellulitis
A man in his 20s presented with multiple coalescing brownish black macules with irregular borders over the left palm and palmar aspect of the digits, with black pigmentary accentuation over the creases.
#CaseReport