@BoppPtrial
@MBOPmechanistic
complete and 7️⃣4️⃣0️⃣🎯 not only met but surpassed 7️⃣6️⃣3️⃣!
Huge & ❤️felt thanks🙏🏾 to all who helped deliver despite challenges incl COVID19 pandemic.
& most importantly to every patient who placed their trust 🫱🏾🫲🏼 in teams across 55 UK 🏥 to take part.
📢 Recruitment is now COMPLETE to both BOPPP & MBOP! 🥳🥳
A major THANK YOU from us to you ALL for your hard work to get us here! 💙💙💙
We exceeded our recruitment target with a TOTAL of 7️⃣6️⃣3️⃣ recruitment participants! A huge commitment - we couldn't have done it with you ALL!
V proud of this simple idea my wife Seena came up with and began at home. Grown organically over the past 6 weeks to support frontline NHS staff at over 20 hospitals in the UK with over 3,000 boxes delivered so far
@nhswellnessbox1
#nhswellnessbox
@KingsCollegeNHS
@supportkings
Dr. Vishal Patel from
#TeamKings
has launched a wellness initiative, with his wife to help NHS staff on the frontline who are caring for patients with COVID-19. Read the full story here 👉
#NHSWellnessBox
ONLY 1️⃣0️⃣0️⃣ participants left to go till we meet our target 🎯 for BOPPP!
Thank you to you all for getting BOPPP this far! 🤗
To celebrate, we've created a little gif for you all 🎊🎉
Not long left to go! 💪🏽🥳🤞
@DrVishalCPatel
@drmarkmcphail
@DrBenCarter
@AneZamalloa
570 patients recruited and edging ever closer to target of 740. Thank you 🙏🏾🙏🏾 to each & every team at all 55 hospital sites as part of the UK hepatology community for their ongoing dedication and effort in this primary prevention trial💪🏾. We cannot do this without you!
Incredibly humbled to be joined by >80 attendees
@BoppPtrial
collaborator meeting from all over the UK 🇬🇧🏴🇮🇪🏴. Dynamic🚀, enthusiastic🤗 and interactive🫱🏾🫲🏼 delegates; opportunity to share key progress updates📊, (blinded) data📈& say a huge thank you🙏🏾, let’s get this done 🙌🏾
Please share and support our frontline NHS staff battling COVID19 in whatever way you can. This is a really thoughtful initiative that can be scaled up by communities to support local hospitals
@nhswellnessbox1
@KingsCollegeNHS
@supportkings
@NHSuk
A large number of staff are now off due to sickness and isolation which means remaining staff have to work that much harder. Lots of people have been contacting my husband to ask how they can help. So here it is
#nhswellnessbox
Happy International Nurses day to all. I’ve lost count of the number of times a nurse has saved a patient (and me for that matter!) with their presence of mind. They have a unique combination of care, patience, skill and attention to detail. Thank you to every single one of them.
Rifaximin-α💊 in this DB-PC RCT👨🏽🔬👩🏼🔬 in
#cirrhosis
with
#encephalopathy
🧠
⬇️oralisation👅 of gut microbiome💩
⬇️mucin-degrading sialidase-enriched gut bacteria
⬆️gut micro-environment promoting barrier repair🛡
⬇️systemic inflammation♨️
⬇️infection risk☣️
Congratulations to our very own
@KCH_Research
team
@AneZamalloa
and
@drmarkmcphail
for recruiting their 50th patient to BOPPP! Truly fantastic work & a large milestone achieved by the team! Well done 👏💪🏽🎉💯 some special prizes on their way!! Keep up the great work!!! 💚💙💜
Huge thank you🙏🏾to all 53 UK BOPPP site teams for your ongoing commitment & effort💪🏾 in getting ever closer to our recruitment target🎯. Phenomenal national effort🙌🏽, we r nearly there🏔️ but still more to do🏁. It isn’t only about recruitment#️⃣but also
#retention
.
@NIHRresearch
We would like to thank all our BOPPP collaborators for your commitment and hard work!
Without you all, BOPPP wouldn’t have been possible!
We are getting closer to our recruitment target and we need a final push to get BOPPP over line!
@DrVishalCPatel
@drmarkmcphail
@NIHRresearch
Dr Vishal Patel acknowledges his team from KCH/KCL who together are working to improve understanding of cirrhosis - important research given the 400% increase in deaths from liver disease over recent years
#APAM2022
Deconvolution of the cfDNA methylome
Great to meet you in person
@NeilRajJ1
at
#basl2023
@BASLedu
. Was fantastic to see the Brighton pier with ☀️ out! Great meeting, very collegiate & collaborative
@basl_events
. Really great to see so many nurses, pharmacists and AHPs. Bright future indeed for UK Hepatology.
It’s a wrap for BASL2023. Great to meet old friends/make new ones & meet referring colleagues to The Birmingham Liver unit f2f. Collegiate meeting and a sense UK Hepatology in a great place striving 2 improve liver care for patients. Future Hepatologists producing amazing work
We have officially randomised 200 patients to BOPPP! This marks a fantastic milestone!!
(We will be revealing the team that recruited the 200th patient in our Winter newsletter, so keep your eyes peeled 👀)
Thank you to our wonderful teams for their hard work! 💪🏽🎉
Could not agree more.
@ChokshiLab
you have been working with
#RogerWilliams
for >2 decades. And now taken on the mantle of mentoring us at the Institute, just as you always have. It has been a privilege. We will continue to deliver just as he instilled in us. Carpe diem!!!
In line with national consensus we have no choice but to pause recruitment to
@BoppPtrial
and prioritise frontline clinical care
@coronaviruscare
. Details will be circulated to active sites shortly and guidance for managing those participants already recruited.
Alongside
@NIHRresearch
associate PI scheme for
@ASEPTIC_TRIAL
@BoppPtrial
- perfect training for lifelong research alongside clinical practice [FOR ALL!] —> preparation for consultant posts
We are pleased to share our summer Newsletter here on twitter - please have a read 📚
We are super excited to be working our way to 400 participants collectively with all of your help. Thank you all very much for your hard work to date!! Together we will make BOPPP a success! 💪🏽
Amazing to have
@DrVishalCPatel
& the Kings ACLD team as guest speakers at our Birmingham Liver seminars. A superb ACLD programme showcased with high quality practice & champions league patient care. Great to meet, collaborate & see you all. Lots to do in driving fwd care ACLD
We are delighted to join
@BoppPtrial
and give our patients the chance to be part of this national study striving to improve treatment for cirrhosis, life-threatening scarring of the liver. Thank you to our BOPPP team for their hard work opening this study
@AndrewMMoon
@AASLDtweets
@AsraniSumeet
@VishCPatel
I am so proud of putting this session together with Kim Brown. The speakers were terrific. This session stands alone as the best seminar on value based liver care I have ever seen. A testament to the depth of our bench in hepatology
Sometimes you feel like giving up...but our patients keep us going, they are the only reason we are here and we owe them a better future. Nothing else matters. I feel so lucky to be part of such an amazing team
@drmarkmcphail
@VishCPatel
@BoppPtrial
#boppp
Why would a patient with
#cirrhosis
enroll in a placebo-controlled trial?
There are Lots of reasons but Le Boutillier et al asked them. So, here’s the answers in their own words
#livertwitter
@JulianSturdy
@APPGantibiotics
AMR is rapidly becoming THE healthcare issue we must grapple with 💊🧫. The UK🇬🇧 has an opportunity to lead here. Combating AMR needs a combined stewardship approach with healthcare providers, scientists & policymakers, amongst all stakeholders🫱🏾🫲🏼
@BSACandJAC
@Inst_of_Hep
@jac_amr
Thanks to
@LesleyManning18
representing
@SWliverbuddies
providing the voice of people with lived experience at our stigma in arld symposium
@esbra_society
Powerful msg
✅ Language matters
✅ Education for HCPs and patients
✅ Psychological support
Read the latest
#endoscopy
guidance relating to the screening of patients with compensated cirrhosis to identify varices. It replaces the previous interim guidance in 2020 when elective NHS services were temporarily halted due to COVID-19.
Well done 👏🏽 to
@Marilen_St
☺️ presenting our lab 🧬cell free DNA🧬 data providing novel insights into hepatic & extra-hepatic organ stress in chronic liver failure syndromes at meeting Copenhagen 🇩🇰
#cirrhosis
#ACLF
#cfDNA
#livertwitter
@ebtapper
@VishCPatel
I think it was this night when the King’s team all ended up in the stocks! You can hang out with the King’s crew anytime
@ebtapper
Thank you
@REDUCe2study
@YazHaddadin
Sumita Verma - v.grateful to
@AneZamalloa
Veena Ramachandran and Team Liver
@KCH_Research
as well as Interventional Radiology for their efforts to screen, recruit, coordinate and support these patients. Important trial, we must get this done!
Thank you
@alisonthewliss
& coming for a scan. Need to raise awareness of liver disease; many will know someone personally affected; worrying there are many more out there unknowingly undiagnosed. Let’s push for early detection nationally!!
@LiverTrust
@ebtapper
@DebbieShawcros1
I took the opportunity to get a liver scan today to highlight the importance of early diagnosis of liver disease. It's personal in my family, as
@joe_jag
got diagnosed last year.
#Time2DeLiver
1/2
Feel very privileged to win this. Really it’s reflective of everyone’s hard work within the SL NIHR CRN. It’s shouldn’t be just my name but every recruiter, every research nurse, every RDM, and every patient!!! Thank you
@MichaelHenegha8
@BSGTrainees
@PSCSupportUK
Thank you
@ebtapper
🙏🏾
Your support (which was especially welcome when the going’s been tough) is much appreciated by the
@BoppPtrial
team. Thank you always for being a strong advocate for getting this done, and more importantly, robustly.
We had an amazing meet and greet at
@RoyalLondonHosp
yesterday - was great to meet the the BOPPP Research team in person! Thank you for having us and we look forward to the new strategies you'll be implementing to optimise recruitment!! 💪🏽🎉💯
#BOPPP
#ThankYou
#appreciationpost