Karl Nadolsky @DrKarlNadolsky Twitter profile

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Karl Nadolsky

@DrKarlNadolsky

3 years

After seeing dietary discussions on @Twitter again yesterday, we need to keep pushing the evidence-based pragmatic concept that dietary pattern improvements need NOT be mutually exclusive. There should not be “keto docs” and “plant-based docs.” Let’s be patient-oriented docs 👍💪🏽

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Karl Nadolsky

@DrKarlNadolsky

1 year

Confused about the genetics of obesity after the @60Minutes special? @DrNadolsky and I were asked to provide a little bit of nuance to the discussion after so much, “outrage,” on the internet.

‘60 Minutes’ Sparked A Furious Debate Over Whether Obesity Is Mostly Genetic

Is it fair to rule out lifestyle entirely? Experts say probably not.

www.womenshealthmag.com

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Karl Nadolsky

@DrKarlNadolsky

2 years

Example of adult female w/ type 1 #diabetes who has struggled in adult years w/ #obesity started semaglutide ( #Wegovy ) last January before insurance coverage changed; switched to tirzepatide ( #Mounjaro ) recently (on 5mg). 21% #weightloss + markedly reduced insulin requirements

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Karl Nadolsky

@DrKarlNadolsky

3 years

Another awesome trial result for #Semaglutide and weight loss. This time in addition to very intensive lifestyle therapy, as noted by 6% weight loss in placebo group.

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Karl Nadolsky

@DrKarlNadolsky

3 years

Obesity is a disease, by definition, whether one wants to agree or not with that fact. It is a complex disease of excess or abnormal adipose (fat) tissue which drives other disease processes on a spectrum of individual variability in a progressively chronic relapsing manner.

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Karl Nadolsky

@DrKarlNadolsky

2 years

My colleagues (endo & dietitian) just saw healthy young female athlete who feels poorly with concerns “hypoglycemia” on very light #LowCarb diet overly concerned about her #CGM showing glucose in 60-80s mg/dL but scared of 30 mg/dL rise based upon following @glucosegoddesss 😞

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Karl Nadolsky

@DrKarlNadolsky

2 years

Why is this Tro guy obsessed with my brother and get so triggered by basic pragmatic evidence-based concepts that he has to create strawmen and as hominem response? 😂🤦🏼

DoctorTro

@DoctorTro

2 years

What you DON’T NEED for weight loss: - A doctor who promotes supplements & drugs as a cure for obesity - overly focusing on a caloric deficit, while ignoring food quality & relationship to food This doctors is BEYOND terrible, its actually sad

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Karl Nadolsky

@DrKarlNadolsky

3 years

Why are artificial sweeteners such an emotionally charged topic? Clinically meaningful outcomes from actual interventional data matter more than hypotheticals. See my counterpoint

Nick Norwitz

@nicknorwitz

3 years

Are artificial sweeteners bad for you? For most people, probably. But that’s fine don’t talk to me 🧱 🧱, talk to Nature 👇 And what’s wrong with just drinking water anyway?

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Karl Nadolsky

@DrKarlNadolsky

3 years

Evidence-based guidelines: Low-carb diets are beneficial, low-fat diets are beneficial, plant-based diets are beneficial, Mediterranean etc but personalize therapy 🥗🐟🥑 Physicians & dieticians: "OK, let's tailor nutrition therapy to individuals." Dietary evangelicals: "F&$!k"

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Karl Nadolsky

@DrKarlNadolsky

2 years

Low- and No-Calorie Sweetened Beverages and Body Weight and Cardiometabolic Risk meta-analysis As established, artificially sweetened beverages are better for weight and metabolic health than sugary beverages. via @JAMANetworkOpen part of @JAMANetwork

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Karl Nadolsky

@DrKarlNadolsky

6 months

It is well known that higher saturated fat (SFA) intake, with nuanced differences between types of foods and types of SFA, increase low density lipoproteins (LDL) and thus cardiovascular risk (heart attack, strokes, etc). @DrNadolsky @Drlipid @davidludwigmd @AdrianSotoMota

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Karl Nadolsky

@DrKarlNadolsky

3 years

Sincere congrats to my younger brother, @DrNadolsky . He recently completed fellowship & passed his board examination, now officially certified by the American Board of Clinical Memology. He is also recognized as a fellow by the American College of Memology (FACM). Very proud!

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Karl Nadolsky

@DrKarlNadolsky

2 years

It is nice to see @garytaubes come around to the science acknowledging with @drnadolsky that an energy deficit, even with high carb intake, results in #WeightLoss rather than claiming carbs—>insulin—> obesity or that #LowCarb ( #LCHF ) is the only way.

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Karl Nadolsky

@DrKarlNadolsky

4 years

6 years ago I did a video thanking @hulkhogan for serving as a positive role model in my youth, influencing me to lift wts etc. Naturally random people took to the comments falsely accusing me of taking anabolic steroids but he came to my defense! @drnadolsky was most stoked 😂

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Karl Nadolsky

@DrKarlNadolsky

3 years

Another red flag of quackery is claiming to be “years ahead of your time” rather than being a part of continued scientific progress + academic discussion. Science/medicine is not some secret society; advances/changes are shared then collaborated etc. @DrAseemMalhotra @DjokerNole

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Karl Nadolsky

@DrKarlNadolsky

9 months

What if #tirzepatide ( #mounjaro , for now) is added to help patients who already achieved meaningful weight reduction via intensive lifestyle efforts? SURMOUNT 3 just presented and published today. #OW2023

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Karl Nadolsky

@DrKarlNadolsky

3 years

Guidance on very low calorie ketogenic dietary prescription from @EASOobesity

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Karl Nadolsky

@DrKarlNadolsky

2 years

Body fat distribution, insulin secretion/levels: Bidirectional Mendelian randomization study: energy excess --> obesity / abdominal obesity --> insulin resistance --> increased insulin levels (T2 #diabetes 2/2 relative insulin deficiency & failure)

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Karl Nadolsky

@DrKarlNadolsky

3 years

For @DrNadolsky ’s social media warriors attacking his diet soda suggestion in please of sugary beverages 😂

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Karl Nadolsky

@DrKarlNadolsky

5 months

Anti‐obesity pharmacological agents for polycystic ovary syndrome: A systematic review and meta‐analysis to inform the 2023 international evidence‐based guideline - Goldberg - Obesity Reviews - Wiley Online Library

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Karl Nadolsky

@DrKarlNadolsky

9 months

FDA Approves #Zepbound ( #tirzepatide ) Medication for Chronic Weight Management @DrNadolsky @BevTchangMD @DrAngelaFitch @MichaelAlbertMD @TheAACE @ObesitySociety @OMAsocial @EASOobesity

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Karl Nadolsky

@DrKarlNadolsky

1 month

Hey @novonordisk & @EliLillyandCo ,, while you are working on reducing cost (like quit spending millions on tv commercials), how about start putting #ozempic , #wegovy , #mounjaro & #zepbound in vials which would help kill several birds with one stone.

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Karl Nadolsky

@DrKarlNadolsky

3 years

Cases of Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets accumulate. 🧀🍳🍗🍖🥩🥓🧈

Extreme elevations of low-density lipoprotein cholesterol with very low carbohydrate, high fat diets

Goldberg and colleagues recently shared in this Journal 5 remarkable cases of extreme hypercholesterolemia associated with increasingly popular very low carbohydrate, high fat diets.1 The authors...

www.lipidjournal.com

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Karl Nadolsky

@DrKarlNadolsky

2 years

EFFECTIVENESS OF MEDICAL NUTRITION THERAPY IN THE MANAGEMENT OF ADULT DYSLIPIDEMIA: A SYSTEMATIC REVIEW AND META- ANALYSIS

Effectiveness of medical nutrition therapy in the management of adult dyslipidemia: A systematic...

Cardiovascular disease (CVD) remains a leading cause of mortality for adults in the United States, accounting for 690,882 deaths in 20201, with substantial health care costs, reaching $378.0 billion...

www.lipidjournal.com

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Karl Nadolsky

@DrKarlNadolsky

6 months

We (DocsWhoLift) certainly once thought that all docs etc should “look” healthy. Then learned that there is more to clinician’s expertise than the cover of their book. Like @DrNadolsky said, some look “fit,” but take drugs like anabolic steroids. Health habits may not “look” it

Andrew D. Huberman, Ph.D.

@hubermanlab

6 months

I think it’s fair to ask if the MD or scientist or public health official saying to do X or not do Y looks and sounds healthy and vital. I avoid going to a dentist with bad teeth. What do you think? I sense diverging opinions on this.

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Karl Nadolsky

@DrKarlNadolsky

3 years

Podcast w/ @DrSarahHallberg on carb restriction improved my impression. Pragmatically not discordant from evidence or how we personalize dietary prescription for obesity & spectrum of adiposity-based cardiometabolic / dysglycemic disease like T2DM.

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Karl Nadolsky

@DrKarlNadolsky

2 years

#tirzepatide + glargine resulted in outstanding weight loss and glycemic improvements in those with #ibesity and type 2 #diabetes JAMA. 2022;327(6):534-545. doi:10.1001/jama.2022.0078

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Karl Nadolsky

@DrKarlNadolsky

4 years

Case series showing more individualized concern with #keto or #LCHF (low carb high fat) diets similar to what we've ( @DrNadolsky and I've) seen and reported (especially depending on the way it's done).

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Karl Nadolsky

@DrKarlNadolsky

3 years

Personalizing dietary therapy is key for everyone. Individualizing one’s dietary pattern toward a “Mediterranean diet” can be a healthy approach in the management of menopause-related obesity / adiposity-based disease and cardiometabolic complications.

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Karl Nadolsky

@DrKarlNadolsky

7 months

500 mg/day of sunflower seed extract in #obesity led to improvements in body fat/weight, body mass index, and hip circumference without adverse effects after the intake of sunflower seed extract compared to the changes in the placebo group. #SeedOils 😉

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Karl Nadolsky

@DrKarlNadolsky

6 months

Actually this not true and actually treating the root of obesity-associated hypogonadism (GLP, surgery etc) is appropriate as noted by @DrNadolsky . @TheAACE @TheEndoSociety @ObesitySociety @ASMBS

Adipose Tissue Dysfunction and Obesity-Related Male Hypogonadism

Obesity is a chronic illness associated with several metabolic derangements and comorbidities (i.e., insulin resistance, leptin resistance, diabetes, etc.) and often leads to impaired testicular...

www.mdpi.com

Ashley Winter MD || Urologist

@AshleyGWinter

6 months

In my opinion every single man with obesity considering a GLP1 should first be assessed for hypogonadism and have that effectively treated first, if present. Many, many, individuals will no longer need a GLP1 if they have a testosterone level that is normalized.

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Karl Nadolsky

@DrKarlNadolsky

3 years

I was tagged in this because @drmarkhyman is always giving advice contrary to evidence-based recommendations from the scientific/medical community without appropriately citing any legit source. It confuses people. @ClevelandClinic , let’s do better @QuackDetector @QuackeryDog

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Karl Nadolsky

@DrKarlNadolsky

2 years

Are cholesterol/lipid trajectory patterns over the life course associated with heart disease risk in midlife? In this cohort discrete lifetime lipid trajectories were associated with subclinical atherosclerosis in midlife.

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Karl Nadolsky

@DrKarlNadolsky

10 months

Not a f*#%ing week goes by that I don’t have a patient referred for obesity + complications who has history of weight gain after sexual or other abuse/trauma as child or adolescent. So heartbreaking and infuriating. 💔

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Karl Nadolsky

@DrKarlNadolsky

7 months

Friends and family tease me about my relatively regimented sleep. What do I know, I’m just a clinical endocrinologist who specializes in cardiometabolic health and a shill for lifestyle optimization. That’s fine 😂 @DrNadolsky

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Karl Nadolsky

@DrKarlNadolsky

3 years

Some people also believe dietary fat is the cause of obesity 😜

Dr. Spencer Nadolsky

@DrNadolsky

3 years

Today, some people believe in the Easter Bunny, some people believe carbohydrates are the cause of obesity. Happy Easter!

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Karl Nadolsky

@DrKarlNadolsky

2 years

Demonizing fruit for those with obesity & type 2 #diabetes (or type 1 for that matter) is very narrow-minded and simply/acutely glucocentric rather than holistic. @nicknorwitz @harvardmed @DrNadolsky 😉🍐🍓🫐🥝😉💪🏽

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