Jason Andrade @DrJasonAndrade Twitter profile

Pinned Tweet

Jason Andrade

2 years

Here the link to our study examining the effect of first-line ablation vs AAD on AF progression. Thanks to @AHAScience for welcoming me back to present the results, and to @NEJM for the simultaneous publication. @CCI_CIC @UBCDoM @CHRS_SCR @SCC_CCS

Progression of Atrial Fibrillation after Cryoablation or Drug Therapy | NEJM

Atrial fibrillation is a chronic, progressive disorder, and persistent forms of atrial fibrillation are associated with increased risks of thromboembolism and heart failure. Catheter ablation as in...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

4 years

Last week I did zoom ECG teaching. I thought I’d use this thread to share some of the more interesting ECGs I found while prepping. Here’s the first - May not seem remarkable at first glance but I’ve never seen it before (though I have seen something similar).

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Jason Andrade

@DrJasonAndrade

2 years

@haithamahmedmd I’d argue a full eval is needed irrespective. Always best to approach these circumstances with open perspective.

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Jason Andrade

@DrJasonAndrade

4 years

So pleased to présent EARLY-AF this morning @AHAMeetings - Largest first line ablation study. - Continuous monitoring in all. - Aggressive AAD use. - No cross-overs. @CANet_nce @HeartandStroke @UBCDoM @VCHResearch @UBCmedicine @CCI_CIC @ScienceVancity

Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation | NEJM

Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line ablation may be more effective in m...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

10 months

The 2023 ACC/AHA guidelines have elevated the role of catheter ablation as the initial treatment of AF. As a topic that has been near and dear to my heart for the past 10 or so years, it’s fantastic to see the field evolve towards offering more effective treatments earlier

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Jason Andrade

@DrJasonAndrade

6 years

Yesterday I had the privilege to present the results of the CIRCA-DOSE trial as part of the late breaking trials session at #EHRA2019 . For those that missed it I thought I would recap the presentation in this thread. @escardio @VCHResearch @HeartandStroke @UBCDoM

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Jason Andrade

@DrJasonAndrade

3 years

Many thanks to the @WhitecapsFC for honouring me as the frontline hero of the match. Knowing we have the support of our community is a wonderful feeling after the significant challenges over the last 20 months. On behalf of my colleagues @VCHhealthcare & @CCI_CIC I’m honoured.

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Jason Andrade

@DrJasonAndrade

4 years

As immensely proud as I am for the entirety of the comprehensive 2020 CCS/CHRS atrial fibrillation guidelines...this sentence alone gives me immense joy.

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Jason Andrade

@DrJasonAndrade

6 years

1. Earlier in December I had the privilege to speak at the Cardiovascular Collaborative Medicine Conference in Manhattan on the role of catheter ablation post CABANA. I thought I'd present that talk via tweetorial. I'm not sure how well it will adapt to this form, but here goes..

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Jason Andrade

@DrJasonAndrade

5 years

1/ In October 2018 the @SCC_CCS released an update to the AF guidelines. This update included a significant revision of the recommendations for anticoagulation therapy around cardioversion. Space limited the discussion so...

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Jason Andrade

@DrJasonAndrade

11 months

ARTESIA results presented by Jeff Healey. - significant 37% reduction in stroke/embolism with apixaban vs aspirin - less severe and disabling strokes with apixaban - roughly a doubling in major bleeding vs aspirin.

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Jason Andrade

@DrJasonAndrade

1 year

Big changes in the recommendations around driving for patients with cardiovascular conditions.

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Jason Andrade

@DrJasonAndrade

4 years

Yesterday we presented the 2020 @SCC_CCS atrial fibrillation guidelines. This comprehensive renewal is the result of two years of collaboration, involving 40 authors, 10 external reviewers, 6 societies, and esteemed patient partners ( @HeartLifeCanada ).

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Jason Andrade

@DrJasonAndrade

4 years

I was supposed to be in Amsterdam at ESC but COVID obviously altered those plans. Instead we undertook a 2500 km road trip through western Canada. Below are 4 photos demonstrating the varied landscape in Lake Louise and Drumheller AB, and Revelstoke and Penticton BC.

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Jason Andrade

@DrJasonAndrade

10 months

@RashadKhaziSyed @drpaari @narrowQRS @MarkMarieb We’ve shown that 44% of untreated PVCs spontaneously resolve at 3-64 months.

Outcomes of untreated frequent premature ventricular complexes with normal left ventricular function

Objective The natural history of frequent premature ventricular complexes (PVCs) in association with preserved left ventricular ejection fraction (LVEF) is uncertain. The optimal management of this...

heart.bmj.com

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Jason Andrade

@DrJasonAndrade

4 years

EARLY-AF is now in print at @nejm I extend a hearty thank you and congratulations to all 18 of our collaborating sites, committee members, coordinators, and most importantly, patient partners. @UBCDoM @VCHResearch @msfhr @HeartandStroke @CANet_nce

Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation | NEJM

Guidelines recommend a trial of one or more antiarrhythmic drugs before catheter ablation is considered in patients with atrial fibrillation. However, first-line ablation may be more effective in m...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

6 years

Just casually reading holter monitors on a sunny Sunday am...

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Jason Andrade

@DrJasonAndrade

1 year

1. Today I presented the late breaking results of our clinical trial examining AF progression after catheter ablation. This was a long-term follow up of the CIRCA-DOSE population, a group of 356 patients randomised to Contact force RF or Cryoballoon PVI

Cryoballoon or Radiofrequency Ablation for Atrial Fibrillation Assessed by Continuous Monitoring |...

Background: Advanced generation ablation technologies have been developed to achieve more effective pulmonary vein isolation (PVI) and minimize arrhythmia recurrence after atrial fibrillation (AF)...

www.ahajournals.org

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Jason Andrade

@DrJasonAndrade

4 years

Why is paroxysmal AF defined as continuous episodes lasting seven days? @PrashSanders @ABollmannMD @SCC_CCS @escardio @hrs_journal @TinaBaykaner @UBCmedicine @HeartandStroke

Atrial Fibrillation Episode Duration and Arrhythmia Recurrence Following Ablation

This secondary analysis of a randomized clinical trial evaluates the association of baseline atrial fibrillation episode duration with post–atrial fibrillation ablation arrhythmia outcomes.

jamanetwork.com

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Jason Andrade

@DrJasonAndrade

2 years

Interesting data out of Ontario Canada. One in five patients waiting for AF ablation died, was hospitalized, or visited the emergency department for atrial fibrillation or heart failure. Events 50% more for paroxysmal AF. Mean wait time 244 days.

Variation and clinical consequences of wait-times for atrial fibrillation ablation: population...

AbstractAims. Atrial fibrillation (AF) is the most common cardiac rhythm disorder. Emerging evidence supporting the efficacy of catheter ablation in managi

academic.oup.com

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Jason Andrade

@DrJasonAndrade

1 year

I had a recent case that I thought was a good example to initiate a discussion within our community. Late 60s, OSA, Inflammatory arthritis, Elevated DR-FLASH Score. Persistent AF No history of cardiac intervention. This was the baseline voltage map in sinus rhythm.

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Jason Andrade

@DrJasonAndrade

5 years

Not exactly the thing you expect to see when you interrogate a loop recorded in the Emergency Department. Strip is continuous.

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Jason Andrade

@DrJasonAndrade

3 years

Ever wonder about the effectiveness of medical therapy for idiopathic frequent PVCs (>5%)? - Beta-blockers and Calcium channel blockers are ineffective. - Class I and III Antiarrhythmic drugs were more effective but suppressed PVCs (to <1%) in only 1/3

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Jason Andrade

@DrJasonAndrade

5 years

A new dedicated EP lab needs a new mapping solution. Thanks to the @VGHFdn we were able to acquire the first @BSCCardiology Rhythmia system in Western Canada. Lumipoint and DirectSense are interesting tools to add to our growing Heart Rhythm program. @UBCDoM @VCHResearch

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Jason Andrade

@DrJasonAndrade

5 years

I’m happy to announce CIRCA-DOSE has now been published in @CircAHA Again, many thanks to my collaborators, mentors, and colleagues. This project began with an animal study as a fellow at @ICMtl and grew into a multicenter @HeartandStroke funded RCT.

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Jason Andrade

@DrJasonAndrade

1 year

Our recent review on asymptomatic AF - in it we discuss important management differences between asymptomatic AF and Subclinical/DDAF. @MarcDeyell @RBennett_EP

Assessment and management of asymptomatic atrial fibrillation

Atrial fibrillation (AF) is the most common sustained cardiac dysrhythmia encountered in practice. It is currently estimated that AF affects approximately 2% of the general population; however, the...

heart.bmj.com

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Jason Andrade

@DrJasonAndrade

4 years

As someone who is today days old, I have not had a large study published in @NEJM So it’s absolutely amazing that young Thomas Khairy has a first author publication in @NEJM at 15! Hearty congrats to my friends at @ICMtl and Marie-Andrée in particular

Infections Associated with Resterilized Pacemakers and Defibrillators | NEJM

Access to pacemakers and defibrillators is problematic in places with limited resources. Resterilization and reuse of implantable cardiac devices obtained post mortem from patients in wealthier nat...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

2 years

INVICTUS doesn’t change the current recommendations regarding valvular AF present in the @SCC_CCS @escardio or @AHAScience AF guidelines. But that’s why it is big news. I expected it would.

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Jason Andrade

@DrJasonAndrade

5 years

Out with the old, and in with the new (EP lab). Thanks to @VGHFdn , the division of cardiology at @VCHhealthcare , the project managers, and staff who helped us realise our goal of providing arrhythmia care to British Columbians in our new dedicated EP lab. @adriandix @Philips

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Jason Andrade

@DrJasonAndrade

4 years

Join us Monday am at #AHA20 LBCT 6 when we will present the results from the EARLY-AF study. 303 patients randomised to cryoballoon vs AAD therapy as 1st line treatment. All patients had a loop recorder.

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Jason Andrade

@DrJasonAndrade

4 years

Found this in my files while preparing for an upcoming talk. I feel like it summarises the discourse. Most of science is iterative and inching towards truth. Uncertainty is the norm. The eureka moments are rare. Science is process and progress. @drjohnm

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Jason Andrade

@DrJasonAndrade

1 year

Interesting results from CASTLE-HTx Will require a deeper dive but interesting that the survival curves differ so much from that observed in CASTLE, particularly since the populations aren’t that different. Congrats to ⁦ @chris_sohns ⁩ et al

Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation | NEJM

The role of catheter ablation in patients with symptomatic atrial fibrillation and end-stage heart failure is unknown. We conducted a single-center, open-label trial in Germany that involved patien...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

3 years

Our systematic review on atrial flutter and heart failure is available in @ESC_Journals In contrast to atrial fibrillation, there is little evidence looking at the implications of flutter on HF outcomes, nor dedicated trials to guide management decisions.

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Jason Andrade

@DrJasonAndrade

5 years

I don’t usually post non-work related stuff. But. Here’s my son in the LA Forum sitting at Paul’s kit before the final Slayer show. @JDMossMD

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Jason Andrade

@DrJasonAndrade

2 years

Commotio Cordis (cardiac arrest secondary to blunt, nonpenetrating trauma to the chest wall) usually occurs in younger men with more malleable & thinner chest walls. However it rarely occurs in those > 20, particularly with underlying cardiomyopathy

Clinical Profile and Spectrum of Commotio Cordis

Context Although blunt, nonpenetrating chest blows causing sudden cardiac death (commotio cordis) are often associated with competitive sports, dangers implicit in such blows can extend into many...

jamanetwork.com

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Jason Andrade

@DrJasonAndrade

1 year

For those who were present at my debate with ⁦ @drjohnm ⁩ - the paper I referenced regarding the increasing safety of AF ablation is now available In short / major complications have decreased over the last decade, highlighting our progress as a field

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Jason Andrade

@DrJasonAndrade

3 years

Please see our Stare of the Art review in @JACCJournals regarding the role of first line cryoballoon ablation versus AAD therapy. We explore the effect if first-line ablation on arrhythmia recurrence, QOL, and healthcare utilisation. @omwazni @UBCDoM

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Jason Andrade

@DrJasonAndrade

6 years

Today the 2018 @SCC_CCS atrial fibrillation guideline update was released. This year we added several sections. The first is a significant discussion on the role of cardiovascular risk factors on AF incidence and progression. @PrashSanders @DrScottLear

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Jason Andrade

@DrJasonAndrade

1 year

Fascinating results from NOAH - not only was OAC for subclinical AF not associated with benefit, but there was net harm with the therapy.

Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes | NEJM

Device-detected atrial high-rate episodes (AHREs) are atrial arrhythmias detected by implanted cardiac devices. AHREs resemble atrial fibrillation but are rare and brief. Whether the occurrence of ...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

4 years

Our paper on autonomic alterations after pulmonary vein isolation is now available. Using the CIRCA-DOSE dataset we were able to perform an in-depth analysis of heart rate response and HRV pre- and post PVI. @MDTolgaAksu

Autonomic Alterations After Pulmonary Vein Isolation in the CIRCA‐DOSE (Cryoballoon vs Irrigated...

www.ahajournals.org

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Jason Andrade

@DrJasonAndrade

5 years

First copies arrived today. Many thanks to @Cardiotext for partnering with us, and to my esteemed co-authors for their hard work and dedication. @MarcDeyell @CCSPrez @StanleyNattel @ICMtl @VCHResearch @UBCDoM

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Jason Andrade

@DrJasonAndrade

6 months

We recently performed the first pulsed field ablation procedures in Canada A heartfelt thank you to @VGHFdn for their commitment to excellence and their dedication to our community's well-being. Together we are ensuring that quality healthcare is accessible to people living in BC

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Jason Andrade

@DrJasonAndrade

4 years

Happy to share the news that our recent AF screening study using @AliveCor Kardia devices in 334 primary care practices has been accepted at @pace_journal . We found AF in 7% of screened patients, with >4% of screened patients newly starting OAC.

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Jason Andrade

@DrJasonAndrade

2 years

Our paper examining atrial fibrillation burden and Healthcare utilization/quality of life from the CIRCA-DOSE study is now available in the European Heart Journal ⁦ @CCI_CIC ⁩ @UBCDoM ⁩ ⁦ @ICMtl ⁩ ⁦⁦ @VCHResearch ⁩ ⁦ @HlthResearchBC ⁩

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Jason Andrade

@DrJasonAndrade

4 years

I’ve tweeted about this before, but happy to report our article on same day discharge in 2400 patients after AF ablation is now in print Interesting in that it may take on a new perspective in the COVID era of trying to avoid prolonged hospitalisations

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Jason Andrade

@DrJasonAndrade

2 years

First-Line AF Ablation Cuts Risk of Progression vs Drug Therapy

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Jason Andrade

@DrJasonAndrade

1 year

Super interesting study. Key points to me - things get worse while waiting for ablation but - delaying ablation one does not cause harm at 1 year (in terms of post ablation recurrence). Suggests to me that the current DAT (Dx-ablation-time) threshold of a year is reasonable

Dominik Linz

@Dominik_Linz

1 year

#EHRA2023 #LBCT Jonathan Kalman Impact of catheter ablation timing on arrhythmia outcomes Early ablation (<1 mth) vs Delayed #AFib ablation (12 mths) 👉🏻 No difference in rhythm outcome…

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Jason Andrade

@DrJasonAndrade

1 year

Congrats to @VivekReddyMD and collaborators on the publication of the ADVENT randomised clinical trial. It’s incredibly important that we continue to pursue comparative trials as we consider adopting new technologies into practice.

Pulsed Field or Conventional Thermal Ablation for Paroxysmal Atrial Fibrillation | NEJM

Catheter-based pulmonary vein isolation is an effective treatment for paroxysmal atrial fibrillation. Pulsed field ablation, which delivers microsecond high-voltage electrical fields, may limit dam...

www.nejm.org

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Jason Andrade

@DrJasonAndrade

5 years

Considering the hours of work we put into our research, and manuscript preparations, and resubmissions, it is lovely to receive such kind words from the reviewer. These small acts of kindness are simple but important. It’s something I will now be incorporating into my reviews

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Jason Andrade

@DrJasonAndrade

4 years

This @BiosenseWebster PFA live case with @tomdepotter is remarkable. In clinic #AFSymposium2021

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Jason Andrade

@DrJasonAndrade

2 years

I had a wonderful visit in Tokyo with Professor Yamane. His accomplishments and knowledge speaks for itself, but more importantly he is a wonderful and kind man, who extended me the most wonderful hospitality. I look forward to returning and am hopeful for future collaboration.

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Jason Andrade

@DrJasonAndrade

2 years

Early morning water taxi to my first Venice Arrhythmia. I’m looking forward to a busy three days.

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Jason Andrade

@DrJasonAndrade

3 years

I live my @Apple watch. But this is definitely not the tracing I expected after a rowing workout.

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Jason Andrade

@DrJasonAndrade

8 months

It was a privilege to participate in the lead sessions for #BostonAF day two speaking about Ablation and AF progression alongside important talks from @Phiso_de S. Willems D. Packer F. Marchilinski

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Jason Andrade

@DrJasonAndrade

11 months

Exciting start to the World Congress of Arrhythmia in Istanbul. @MDTolgaAksu performing a live Cardioneural ablation case for vasovagal syncope.

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Jason Andrade

@DrJasonAndrade

3 years

There is a lot of discussion about how to monitor for AF, ( binary recurrence or burden), but less discussion about how monitoring influences these outcomes Now in print @CircAHA we aimed to address this, with a goal of informing trial design & practice 1/

Influence of Monitoring Strategy on Assessment of Ablation Success and Postablation Atrial Fibril...

Background: Various noninvasive intermittent rhythm monitoring strategies have been used to assess arrhythmia recurrences in trials evaluating pharmacological and invasive therapeutic interventions...

www.ahajournals.org

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Jason Andrade

@DrJasonAndrade

6 years

Happy to share that our recent publication on “best practices” with cryoballoon-based pulmonary vein isolation is now available onsite and is open access. The focus is dosing and monitoring. It was a pleasure to collaborate with such a great group.

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Jason Andrade

@DrJasonAndrade

5 years

Does anyone know why persistent AF is defined as an episode longer than 7 days? Is there pathophysiological evidence justifying this? Why not 5 days? Or 48h? @dgwyse @drjohnm @Ed_Gerst @PassmanRod @DrBradleyKnight @HughCalkinsMD @atulverma_md @DhirajGuptaBHRS @andreanatalemd

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Jason Andrade

@DrJasonAndrade

6 years

1/3 Haven’t had time to fully digest the new atrial fibrillation guideline. But I find it surprising that the ACC/AHA/HRS would endorse Apixaban use in dialysis patients. @hswapnil @brownpa79 @kidney_boy

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Jason Andrade

@DrJasonAndrade

5 years

Thanks! It was a surprise and honour to receive this recognition from @uOttawaMed I had a great time catching up with old friends at my alma mater last weekend.

UBC Department of Medicine

@UBCDoM

5 years

🎉Congratulations to @DrJasonAndrade (Cardiology) on receiving @uOttawa 's Rising Star Achievement Award recognizing an outstanding alum who models professional excellence and exceptional leadership while making significant contributions to medicine. Visit:

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Jason Andrade

@DrJasonAndrade

6 years

Happy to announce that our @HeartandStroke funded CIRCA-DOSE study comparing cryoballoon to contact force PVI was accepted as a late breaking clinical trial at EHRA @escardio @UBCDoM @HH4EHRA @VCHResearch @MDT_Cardiac @BiosenseWebster

Randomised clinical trial of cryoballoon versus irrigated radio frequency catheter ablation for...

Introduction Pulmonary vein isolation (PVI) is an effective therapy for paroxysmal atrial fibrillation (AF), but it has limitations. The two most significant recent advances have centred on the...

bmjopen.bmj.com

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Jason Andrade

@DrJasonAndrade

2 years

@darth @MikeLounds

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Jason Andrade

@DrJasonAndrade

5 years

It’s been a few years since I’ve done cases with @AbbottCardio EnSite Precision. Despite my early EP career being NAVx for all mapping cases, i have spent the past 5 years almost exclusively using @BiosenseWebster CARTO (except Pediatric cases) This was my first with the HD Grid

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Jason Andrade

@DrJasonAndrade

1 year

Many thanks to @ourvancouvermsa for the Scientific Achievement Award. It’s a testament to our EP community in Canada that we’ve been able to achieve so much together. @VCHhealthcare @UBCDoM @CHRS_SCR

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Jason Andrade

@DrJasonAndrade

4 years

@Caulimovirus

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Jason Andrade

@DrJasonAndrade

3 years

#EPeeps - Catheter ablation of persistent AF remains a challenge, given the mechanisms sustaining persistent atrial fibrillation remain unclear. Extra-PVI strategies have not consistently demonstrated benefit beyond PVI alone. What about drivers from ECGi?

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Jason Andrade

@DrJasonAndrade

2 years

EARLY-AF listed in the NEJM Journal Watch Cardiology Top Stories of 2022 Thanks again to the patients and collaborators for enabling this research program, and being so committed to addressing the question of “best initial treatment for AF”

Top Stories of 2022

www.jwatch.org

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Jason Andrade

@DrJasonAndrade

5 years

Second addition of the cardiac electrophysiology handbook is now available. Many thanks to my co-authors for their valuable contributions @MarcDeyell @CCSPrez Laurent Macle, Matt Bennett, Nat Hawkins @UBCmedicine @VCHResearch @SchakrabartiEP @ECG_Emily @ICMtl

Cardiotext

@Cardiotext

5 years

Just published! - congratulations to Dr. Jason Andrade for his comprehensive update to the bestselling Clinical Cardiac EP Handbook - now available in a new second edition. @DrJasonAndrade

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Jason Andrade

@DrJasonAndrade

1 year

7. To conclude PVI performed by contact force RF and cryoballoon are equally efficacious at preventing recurrence and reducing AF burden detected on ILR. But progression rates differed by ablation energy.

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Jason Andrade

@DrJasonAndrade

2 years

Congrats to ⁦ @Elliott_AD ⁩ ⁦ @PrashSanders ⁩ ⁦ @melissaemm1 ⁦ @DH_Lau ⁩ and colleagues on Exercise and Physical Activity Program in Patients With Atrial Fibrillation: The ACTIVE-AF Randomized Controlled Trial - great work!

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Jason Andrade

@DrJasonAndrade

2 years

#EPeeps - The S-ICD is a major step-forward in device therapy for the prevention of sudden death, however, Inappropriate shocks occur twice as frequently with S-ICD compared to standard transvenous ICD. One reason is due to change in ECG over follow-up.

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Jason Andrade

@DrJasonAndrade

1 year

We know progression from paroxysmal AF to persistent AF is associated with worse outcomes. And we know Cryoballoon ablation decreases progression vs AAD therapy. Join us at ESC for late-breaking science comparing cryoballoon ablation and RF ablation

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Jason Andrade

@DrJasonAndrade

3 years

I feel immensely privileged to have had known Dr Wyse ( @dgwyse ). George was such a caring, kind and wonderful man who, despite his landmark accomplishments, was approachable and humble. And he gave that most precious thing, his time. Raise a 🍷 to them.

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Jason Andrade

@DrJasonAndrade

4 years

Preparing for @westernAFib and came across this quote. Sums up the difficulty with assessing QOL in AF. “A fugitive illness that only visits a patient periodically may be more difficult to bear than one whose effects are durable and persistent.”—William Evans, 1959.

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Jason Andrade

@DrJasonAndrade

1 year

Packed room to learn about when NOT to ablate AF, WPW, PVCs and Flutter. A session for thé #medicalconservative @drjohnm

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Jason Andrade

@DrJasonAndrade

4 years

I’m pleased to shared that our sex-based differences in AF is now published in @JACCJournals clinical electrophysiology. @UBCmedicine @msfhr @HSF_science

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Jason Andrade

@DrJasonAndrade

3 years

Have you ever wondered about the clinical factors that predict perforation during Lead Extraction? Now available in @hrs_journal are the Results of the Canadian Lead ExtrAction Risk (CLEAR) Study from Bashir et al. #HRStweetorialtuesday #EPeeps @CCI_CIC @CHRS_SCR @UBCDoM

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Jason Andrade

@DrJasonAndrade

4 years

Massive thanks to: @atulverma_md for his guidance and mentorship. Patricia Theoret-Patrick @uOttawa for coordinating the trials. Li Chen and George Wells for their statistical analysis and methodology. And all the patient partners at our 18 participating sites across Canada.

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Jason Andrade

@DrJasonAndrade

9 months

Looking forward to partnering on this journey to evaluate the role of first-ablation for persistent af. Exciting times!

Boston Scientific

@bostonsci

9 months

The AVANT GUARD clinical trial has commenced and will evaluate the safety and effectiveness of the FARAPULSE™ Pulsed Field Ablation (PFA) System as a first-line treatment for persistent atrial fibrillation (AF). Learn more:

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Jason Andrade

@DrJasonAndrade

4 years

@ShaunMohan4 @mattaustein @adribaran @SergioPinski Close. Patient had HCM with substantial LAE. ECG is showing a fibrillating left atrial appendage that had been isolated from the rest of the atria.

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Jason Andrade

@DrJasonAndrade

4 years

Happy Father’s Day to all the dads. This picture was from my son, drawn as a homeschool project a few weeks ago.

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Jason Andrade

@DrJasonAndrade

4 years

Please see the attached important communication from the @CHRS_SCR Device committee on the potential interaction between @Apple iPhones / MagSafe accessories and implanted cardiac electronic devices. @MedtronicCA @BSCCardiology @AbbottCardio @MicroPortEP @BIOTRONIK_News @SCC_CCS

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Jason Andrade

@DrJasonAndrade

2 years

Thanks to ⁦ @DLBHATTMD ⁩ and ⁦ @ACCinTouch ⁩ for naming EARLY-AF as one of the top 10 clinical trials of 2022. ⁦ @UBCDoM ⁩ ⁦ @VCHResearch ⁩ ⁦ @CCI_CIC ⁩ ⁦ @HeartInstitute ⁩ ⁦ @ICMtl ⁩

2022 Top Journal Scans and Clinical Trials - American College of Cardiology

www.acc.org

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Jason Andrade

@DrJasonAndrade

3 years

As our analysis of the natural history and significant of early recurrences of atrial arrhythmia is now in press at @hrs_journal I thought I would do a quick tweet-rial of the key findings @SCC_CCS @CHRS_SCR @UBCDoM @VCHResearch @HughCalkinsMD @MarcDeyell

Prevalence and outcome of early recurrence of atrial tachyarrhythmias in the Cryoballoon vs...

Early recurrence of atrial tachyarrhythmia (ERAT) is common after pulmonary vein isolation (PVI) and has been associated with an increased risk of late atrial fibrillation (AF) recurrence.

www.heartrhythmjournal.com

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Jason Andrade

@DrJasonAndrade

1 year

Our review in @JACCJournals discussing ablation as a means to reduce AF burden. Congratulations to Hannah Schwennesen on leading this review, and many thanks to Kathryn Wood and @JonPicciniSr for inviting me to collaborate on this important topic.

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Jason Andrade

@DrJasonAndrade

3 years

Congratulations to @nmarrouche and colleagues for undertaking this important trial. Clearly lots to unpack in a trial of this magnitude. At a minimum it highlights that earlier intervention is better, before the scar has had time to progress to stage 3/4.

European Society of Cardiology

@escardio

3 years

#DECAAF II trial: fibrosis #ablation shows promise in #AFib with low grade fibrotic myopathy #ESCCongress

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Jason Andrade

@DrJasonAndrade

3 years

#EPeeps - did a recent redo ablation procedure for atypical flutter. Attached is the voltage map with Rhythmia. The clinical arrhythmia ended up being a right free wall atypical flutter, but more concerning is that there was ~no measurable voltage in the LA or posterior RA.

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Jason Andrade

@DrJasonAndrade

5 years

As amazing as the scientific program was, my favourite part of my first @westernAFib is depicted in this picture. Where else can you find such joy and comraderie? @drjohnm @EJSMD @PrashSanders @nmarrouche @LuigiDiBiaseMD @guroledip

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Jason Andrade

@DrJasonAndrade

6 years

Dr Scherr offering his insightful commentary on the CIRCA-DOSE results. Re-iterating the differences in the definition of “success” after AF ablation depending on which endpoint you use. 53% time to event vs. 99% reduction in burden. @drjohnm

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Jason Andrade

@DrJasonAndrade

3 years

Now available in @hrs_journal (open access) - Trends in Implantable Cardioverter-Defibrillator Programming Practices and its Impact on Therapies: Insights from a North American Remote Monitoring Registry 2007 – 2018 #HRStweetorialtuesday

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Jason Andrade

@DrJasonAndrade

2 years

Great review of Arrhythmias in Pregnancy | JACC: Clinical Electrophysiology

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Jason Andrade

@DrJasonAndrade

3 years

#EPeeps - Pacing-induced cardiomyopathy occurs in up to 20% of patients after 3–4 years of RV pacing It has been primarily attributed to functional LBBB and LV dyssynchrony induced by RV pacing, thus prevention focuses on resynchrony Do statins offer hope?

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Jason Andrade

@DrJasonAndrade

2 years

Defibrillator allows Daley Blind to play in FIFA World Cup quarterfinal

Netherlands defender Daley Blind would be quite entitled to pinch himself in disbelief when he walks out against Argentina in Friday’s World Cup quarterfinal. He has been able to continue playing...

sportstar.thehindu.com

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Jason Andrade

@DrJasonAndrade

3 years

#EPeeps - Poor R wave progression is a common finding on a standard 12-lead ECG, but its physiological background and clinical significance are still not fully understood. Data from a large health examination survey suggest it may not be benign.

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Jason Andrade

@DrJasonAndrade

10 months

Our article examing the Cost-Effectiveness of First-Line Cryoablation versus First-Line antiarrhythmic drug therapy in the Canadian health care system is now available in @CJCJournals

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Jason Andrade

@DrJasonAndrade

2 years

Great debate with my friend @LuigiDiBiaseMD regarding the optimal ablation strategy for persistent AF. I’m told the session was so well attended that the room capacity was exceeded. #HRS2022 @HRSonline @CHRS_SCR

Firas Zahwe

@Firaszahwe

2 years

#HRS2022 @MoussaMansour10 the real debate for the future what to do post PVI for persistent AF. @HRSonline @LuigiDiBiaseMD @DrJasonAndrade

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Jason Andrade

@DrJasonAndrade

4 years

Important findings in the domain of stroke-prevention for AF. Reaffirms the contemporary definition of non-valvular AF, highlighting that DOACs remain a treatment option in patients with normally functioning bioprosthetic valves. Congratulations to @RenatoDLopes1 and co-authors.

NEJM

@NEJM

4 years

In a trial comparing rivaroxaban with dose-adjusted warfarin, rivaroxaban was noninferior to warfarin with respect to the mean time until the primary outcome of death, major cardiovascular events, or major bleeding at 12 months. #AHA20

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Jason Andrade

@DrJasonAndrade

3 years

#EPeeps - More data indicating EARLY invasive management of AF is associated with improved outcomes Similar to our RCT meta-analysis () this propensity-matched analysis of the KiCS-AF multicenter registry from #Japan showed ↓ HCU

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Jason Andrade

@DrJasonAndrade

1 year

If we move towards first line Cryoballoon ablation then it obliged us to consider the cost impact of earlier intervention. Attached below is a U.S. Medicare based analysis examining the cost effectiveness of first line Cryoballoon ablation @omwazni

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Jason Andrade

@DrJasonAndrade

4 years

Wonderful way to end to #AFSymposium2021 Congratulations to Jeremy Ruskin, @MoussaMansour10 , Vivek Reddy and the organisers for putting together such a fantastic program with such a do raw and esteemed faculty. Can’t wait to do it again in person.

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