iPARPs in HRR negative population read our article!!! 👩🏻⚕️👨⚕️👩🏻⚕️
@ASCO
#ASCOGU23
🇲🇽🇺🇸🇪🇸
PARPi in Patients With HRR-Negative mCRPC: Why Would These Therapies Work in the Absence of a Mutation?
🔸DNA proficient tumor cells tx w iPARP with hormonal agents, radioligands & IO (figures)
Happy to present the CheckMate9ER study
@ASCO
#gu2024
👩🏻⚕️🇲🇽🦀
🔹 A P3 trial of cabo+nivolumab vs sunitinib in previously untreated advanced kidney cancer.
🔸@ 55m folow-up efficacy of the combo is maintained in OS, PFS and ORR
🔹Thanks for the great team and support!
@URONCO
100 Influential Women in Oncology: Key Opinion Leaders to follow on Social Media in 2023
🇺🇸🇯🇴🇨🇦🇳🇬🇮🇳🇧🇷🇲🇽🇦🇺🇬🇧🇳🇱
Today is Women’s Equality Day, celebrating the 1920 law that granted U.S. women the right to vote. Initiated in 1971 and made official in 1973,
📢 BMS
@bmsnews
Press release on CheckMate-67T study of subcutaneous Nivolumab while
@myESMO
begins
🔹P3 trial of SC Nivo vs IV Nivo
🔸Meets co-primary endpoints of Pharmacokinetics 👩🏻🔬
🔹Meets non-inferiority in ORR (secondary endpoint)
Great team
@AlbigesL
@INCMNSZ_Uronco
Happy collaborator: WOMEN, POWER & CANCER
@TheLancet
Commission
Lead by
@OphiraG
& great team
@NarjustFlorezMD
@dmukherji
@EnriqueSoto8
🔸Cancer one of top 3 causes of premature death 🌍
🔹Gender transformative policies needed👩🏻⚕️
🔸Risk fx: Tobacco alcohol obesity & infections
@BourlonMaite
is devoted to professional development of female colleagues as clinicians, educators, and researchers in oncology. Learn more about her and why she's a 2023 International Women Who Conquer Cancer Mentorship Award recipient:
@incmnszmx
Thanks
@ASCO
for the opportunity! 🇲🇽👩🏻⚕️ 💙
Best of journals in Medical Oncology for RCC
#kidneycancer
@IKCCorg
🔸Triple therapy in mRCC
🔹TKI & IO cabo+nivo one of the highest responses in non-clear cell
🔸Pembro continues to have DFS. Atezolizumab & Ipi/Nivo no DFS or OS
📣 Announcing the
#ASCO23
Featured Voices! 🎉 Follow on Twitter, Instagram and/or LinkedIn for a range of expert insights and join the conversation using the official hashtag:
#ASCO23
👉
#oncofertility
in twitter!
🔹 Mostly from high income countries🌎
🔹Tweets are from physicians & healthcare centers, none from patients 👩🏻⚕️👨🏻⚕️
🔹14.5% about children & adolescents
🔹Need strategies to ⬆️ content & awareness in social media
@NayeliMartinezi
Great! “PARPi for prostate cancer”
🔹1st targeted therapy for advanced disease
✅ TRITON-3 & PROFOUND showed benefit in mCRPC w DDR alt
‼️PROPEL, TALAPRO-2 & MAGNITUDE in 1L mCRPC but mostly unexposed to ARSi
Is PARPi rechallenge possible?
@Ecastromarcos
@PaolaVS94
👩🏻⚕️🇲🇽🇪🇸
Adjuvant pembro is rapidly becoming a new standard of care for resected
#RCC
, but how will we treat patients upon metastatic recurrence?
@BourlonMaite
@DrChoueiri
#kcsm
As Women's History Month ends, we're recognizing 2023 Women Who Conquer Cancer Mentorship Awards recipients: Dr. Carolyn D. Runowicz and Dr. María Teresa Bourlon.
Thank you for being leaders for women conquering cancer around the globe.
@BourlonMaite
So happy to chair the “Oral Abstracts Flash track” session
#ASGCR23
@NCIResearchCtr
@NCIGlobalHealth
🔸Self-collected samples for cervical cancer screening Africa & Asia🌍
🔹Smoking cessation campaings in HIV
🔸Novel electronic resources for cancer awareness🏥
Online Networking
Breaking news from
#GU24
: CheckMate-9ER and CheckMate-214 updates continue to show a benefit with checkpoint inhibitor–containing combinations over sunitinib for the 1L treatment of advanced RCC:
#ASCODailyNews
@BourlonMaite
@MDAndersonNews
The urothelial cancer community cannot wait to see the data!!! 👨🏻⚕️👩🏻⚕️🌍
🔸For decades platinum-based chemo was the SOC in 1st line 📣
🔹ADCs + IO combinations were promising 🙏🏻
🔸Cant wait to see the data on EV+pembro and become a new SOC ✌🏻
How do we approach
#penilecancer
in older adults? 👴🏼
🔸Older patients ⬇️ likely to receive surgery, chemo or RT
🔸 Primary surgery associated ⬆️ cancer specific survival
🔸Competing mortality risks important in OS
@TomFlaigMD
@SpiessPhilippe
@simon_p_kim
Just at
#gu2024
@ASCO
🔹Keynote 564! Adjuvant pembrolizumab in resected high risk RCC has OS benefit!
@DrChoueiri
🔸
@PBarataMD
discussed the data & highlighted our ASCO Daily News of What to do in patients recurring after adjuvant pembrolizumab?
Mensaje final del debate “Actualizaciones de las opciones terapéuticas de CCRa en 1L”
@BourlonMaite
@SMEOMX
#SMEO
1️⃣ IO/IO o IO/TKI: mejor estrategia de 1L
2️⃣ El uso de estos combos requiere personal capacitado para el manejo de toxicidad
3️⃣ Incluir al px en ensayos clínicos
Brilliant discussion about controversies in mCSPC conducted by my friend Dr Maluf! Triplet x doublet treatment is still a very debatable point and a better selection of patients is an critical point to improve. Biomarkers are eagerly needed! Congrats for all panelists!
Huge congratulations to
@BourlonMaite
for all her
#ASCO2023
awards. Recipient of both
#40under40
and
#conquercancer
awards, she is truly and inspiring mentor for physicians worldwide. Could not think of a better person for these awards!!
Access to novel drugs for metastatic renal cell carcinoma is an unmet need in the Mexican population 👩🏻⚕️🦀🇲🇽
- We need to work to improve patient outcomes 📣
Lack of access to innovative treatments dramatically affects survival. Greater access to immunotherapy treatment is necessary for patients with renal cell cancer. Great collaborative work of Mexican oncologists led by
@BourlonMaite
and Dra. Nora sobrevilla. Congratulations for
Adjuvant therapy kidney & bladder cancer
#ASCO22
@ASCO
🔹No OS benefit found, just DFS
🔸Need to define NED & disease progression in this studies
🔹Need utility scales & better prognostic scores
🔸Can patients solve this riddle?
@DebMaskens
@apolo_andrea
@IKCCorg
@OncoAlert
The June issue of ONCOLOGY is ready and available to download. This month we feature a urothelial carcinoma clinical quandary by
@BourlonMaite
and a kidney cancer review by Naveed Ahmed Mahar, MBBS.
#oncology
#medtwitter
Really nice work from Dr. Saby George
@RoswellPark
, with
@AlbigesL
@BourlonMaite
and others, looking at subcutaneous nivo administration. Looks very similar to IV in terms of PK, efficacy, safety. Could really change how nivo is delivered in the future
@ASCO
#GU24
Bipolar Andrógeno Therapy for advanced
#prostatecancer
by
@EfstathiouEleni
#ASCOGU23
🔸Androgens revert androgen independence
🔹TRANSFORMER: phase II trial of BAT vs enzalutamide
🔸Offer germline and somatic testing!! Poot prognosis events in HRR 👩🏻🔬
🔹Always offer other options
1/ CheckMate-9ER extended f/u (media f/u=32.9mo) results out in
@TheLancetOncol
: preplanned final OS analysis, updated PFS, OR & safety of Cabo/Nivo vs. Sun in 1L RCC. Also includes prespecified & post-hoc subgroup analyses.
@OncoAlert
@DanaFarber_GU
Outstanding discussion by
@BourlonMaite
at
#ASCO2023
highlighting the developments in the treatment landscape for advanced cisplatin-ineligible urothelial carcinoma. Congrats!
@SalvadorjcMD
👨🏻⚕️🇲🇽presenting our work
#ASCOQLTY23
Inclusion of sex and gender instructions to author a and SAGUER guidelines recommendations across highest impact Oncology Journals
📢Most Oncology journals are not in compliance with guidance for sex and gender reporting
La presente muestra el desarrollo de PARPi en el cáncer de próstata, las sinergias y combinaciones que se están investigando, así como las direcciones futuras de PARPi .DOI. 10.1177/17588359231221337 Participación del
@INCMNSZ
,
@BourlonMaite
#Hemato
-Oncología.
@SMEOMX
Wonderful time
@SMEOMX
2022
#kidneycancer
#bladdercancer
🔸IO/IO & IO/TKI combos are standard in first line in mRCC
🔸Metastatic urothelial carcinoma discussion on challenges of implementing maintenance IO
🔸Excellent RWD on mUC in 🇲🇽by 👩🏻⚕️👨🏻⚕️mentees
@SJaimeC
@RAlejandroOrtiz
Great team effort from Emerging Markets!!
@SoaresAndrey
@tompowles1
@raymanneh
🔹
#globaloncology
perspective on the status of urothelial carcinoma in LMICs 🌍🦀👩🏻⚕️
🚫Lack of cancer registries ▶️ insufficient data on incidence & mortality
‼️Diverse challenges in access to care
The tx of mUC has evolved in the last years, but it is still challenging in the
#LIMC
. In this review, the authors from different regions discuss the gaps, challenges and suggestions to improve mUC care in the
#LMIC
.
@BourlonMaite
@tompowles1
@raymanneh
Abstract 4553: Checkmate 9ER with CaboNivo in 1L
#RenalCellCarcinoma
outcomes by baseline characteristics (IMDC risk, Organ site of mets, # of organ sites with mets, sum of diameters of target lesions) PFS/ORR for all (and OS for most subgroups) favor CaboNivo
@ASCO
#ASCO21
New ESMO eUpdate: ESMO Clinical Practice Guidelines for
#bladdercancer
👉 Maintenance avelumab is recommended in metastatic UC cancers which have not progressed on first-line platinum-based ChT (4-6 cycles) 👉
#blcsm
@Annals_Oncology