Barak Rotblat @BarakRotblat Twitter profile

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Barak Rotblat

7 years

We thought of all the things we love about science and what kind of community we wish to be part of. This is the story of how we held our own international conferences for young PIs.

Nature Careers

@NatureCareers

7 years

How a group of young PIs built a scientific community from a new type of conference.

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Barak Rotblat

@BarakRotblat

2 years

He finshed his confocal session for today

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Barak Rotblat

@BarakRotblat

2 years

Protein running in gel

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Barak Rotblat

@BarakRotblat

3 years

Just got promoted to Associate Prof🥂 Big thank you to my group, you are terrific! And to all the ppl giving their time to make this happen - members of the committees, my department @LsBgu , Faculty of Natural Sciences, @BenGurionUni , and to those who wrote support letters🙏

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Barak Rotblat

@BarakRotblat

11 months

Some good news: I was awarded a Worldwide Cancer research grant to study the role of a mitochondrial chaperone and its co-chaperone in cancer metabolism🔥 A big thank you to @WorldwideCancer and to my students, Hila Ben David and Shani Gabay, for the beautiful data🙏

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Barak Rotblat

@BarakRotblat

4 years

🔥new paper out🔥 This is @AlasadKhawla first first-author paper and she is in the first year of her PhD! It started with a grant rejection because - reviewer: "who cares that 4EBP is over expressed, it is phosphorylated and inactive anyway"

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Barak Rotblat

@BarakRotblat

2 years

🔥NEW PREPRINT!🔥 Glucose is a universal fuel for cells, so we asked how tumor and normal cells survive glucose starvation. 4EBP1/2 support tumorigenicity and cell survival during energetic stress by translationally regulating fatty acid synthesis

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Barak Rotblat

@BarakRotblat

4 years

Small lab presented unpublished data in a big conference

Massimo

@Rainmaker1973

4 years

Something went terribly wrong for both these two fish but they let us see the life of 33 milion years ago

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Barak Rotblat

@BarakRotblat

5 years

Tenure letter and flowers make Barak happy

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Barak Rotblat

@BarakRotblat

4 years

So how is the revision going?

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Barak Rotblat

@BarakRotblat

1 year

Dear friends, my family and I are safe. Thanks for reaching out and showing support 🙏

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Barak Rotblat

@BarakRotblat

4 years

א מ י ת י אישתי עבדה על זה 10 שנים. כל כך שמח לראות את זה בחוץ

Oded Rechavi

@OdedRechavi

4 years

🔥המלצה חמה מ א ו ד 🔥: אם נסעתם או שאתם מתכננים לנסוע לעשות תואר או פוסט דוקטורט בחו״ל (או ללוות בן/בת זוג שחייבים) אתם מוכרחים לקרוא את ספר הביכורים שכתבה ואיירה עדי ברוקס. מצחיק, מרגש ואמיתי. @ScienceAbroad רוצו להזמין!!! הנה האתר של הוצאת פרדס:

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Barak Rotblat

@BarakRotblat

3 years

Peacemongering with @hadarst and our Muslim and Jewish brothers and sisters. Luckily, no missiles during the demonstration

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Barak Rotblat

@BarakRotblat

3 years

🔥New paper out in collaboration with @ToiberDebbie ! Aim 2 in Gal Mazor's PhD was to find how her favorite lncRNA is regulated in GBM. She found it is through YY1. Because YY1 is a master regulator of the aging brain transcriptional program/

TP73-AS1 is induced by YY1 during TMZ treatment and highly expressed in the aging brain | Aging

Aging | doi:10.18632/aging.203182. Gal Mazor, Dmitri Smirnov, Hila Ben David, Ekaterina Khrameeva, Debra Toiber, Barak Rotblat

www.aging-us.com

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Barak Rotblat

@BarakRotblat

3 years

Big thank you to the Israel Cancer Association and reviewers for the grant and for making the new year better🙏🥂

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Barak Rotblat

@BarakRotblat

3 years

@UmoyeAlexis Can't speak for academia but I prefer in-person interaction with students because sometimes something happens when a bunch of ppl get together to discuss science that does not happen online. So yes, if possible I prefer in-person

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Barak Rotblat

@BarakRotblat

3 years

We saw these cute animals from the trail this morning

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Barak Rotblat

@BarakRotblat

1 year

@mbeisen @TheOnion Michael, I think you don't really get what courage is

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Barak Rotblat

@BarakRotblat

3 years

Celebrating @ToiberDebbie tenure 🥂

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Barak Rotblat

@BarakRotblat

2 years

It's a dimer, I'm telling you

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Barak Rotblat

@BarakRotblat

3 years

I'm thrilled to take part in the world exhibition of @portefeuillefun ! I hung the two photos in the hallway between my office and the lab for everyone to enjoy. Thank you Volker for the generous gift of beautiful art 🙏 @LsBgu

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Barak Rotblat

@BarakRotblat

3 years

Spontaneous(ish) lab day trip with our friends the @OdedRechavi lab😎

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Barak Rotblat

@BarakRotblat

4 years

Should they change the "Chemistry" category to "Molecular Biology" or should they just continue to pretend?

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Barak Rotblat

@BarakRotblat

2 years

Cus one poster is not enough #eacrCancerMetabolism

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Barak Rotblat

@BarakRotblat

3 years

Pouring a gel, 2009

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Barak Rotblat

@BarakRotblat

2 years

#ScienceFlashMob @schumacherbj @ToiberDebbie @MayaPifff @AsafLevyHUJI

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Barak Rotblat

@BarakRotblat

1 year

RE- IMAGINING INHERITANCE: GERMLINE MUTATIONS, PLASTICITY & ENVIRONMENT WORKSHOP An @OdedRechavi and @schumacherbj production. A true celebration of science

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Barak Rotblat

@BarakRotblat

4 years

Celebrating @zarivach elected to department chair @LsBgu 🥂

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Barak Rotblat

@BarakRotblat

1 year

Can't be more proud bog Gal Mazor🥂 I'm so lucky to have had her as my first PhD student 🤩

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Barak Rotblat

@BarakRotblat

3 years

🔥New paper out🔥 by Mail Badarni, a joint PhD student with @Elkabetslab 😎 Mai studied acquired resistance to PI3K inhibitors in HPV positive head and neck cancer and found this happens through IGF2 upregulation

IGF2 Mediates Resistance to Isoform-Selective-Inhibitors of the PI3K in HPV Positive Head and Neck...

Over 50% of human papilloma positive head-and-neck cancer (HNCHPV+) patients harbor genomic-alterations in PIK3CA, leading to hyperactivation of the phosphatidylinositol-4, 5-bisphosphate 3-kinase...

www.mdpi.com

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Barak Rotblat

@BarakRotblat

4 years

Made my morning - gave a zoom talk yesterday at the Faculty of Biology @TechnionLive , and today got an email from a student with a great question🙂!

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Barak Rotblat

@BarakRotblat

3 years

Real life undergrad poster session department day Life Sciences @LsBgu and friends

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Barak Rotblat

@BarakRotblat

5 years

📣new paper out!💥 Do mitochondrial chaperones fold all mitochondrial proteins equally? Is there specificity? Do cells up regulate a particular mito-chaperone to facilitate up regulation of a particular mitochondrial protein? What about #cancer ?

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Barak Rotblat

@BarakRotblat

2 years

Ppl love dissing chatGPT. Please consider how helpful it is to non-native English speakers. An email that takes a NS 30 sec to write can take 20 min to a NNS, just to make it decent sounding. Its language may not sound clever but it's coherent. Just a thought 🤔

seven ex machina

@toomanyspectra

2 years

I don’t understand the buzz around ChatGPT it has the writing competencies of a 5th-grader like who is being fooled by this

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Barak Rotblat

@BarakRotblat

5 years

".. cells deficient for both NHEJ and alt-EJ were still able to repair CRISPR-mediated DNA double-strand breaks, highlighting how little is yet known about the mechanisms of CRISPR-based genome editing."

Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells

Scientific Reports - Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells

www.nature.com

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Barak Rotblat

@BarakRotblat

3 years

Our lab's first graduating PhD, Gal Mazor, got us these lovely keychains with molecules, a scope and our initial 🙏 Gal!

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Barak Rotblat

@BarakRotblat

4 years

Was fun chatting about science with Rich :) Thanks 🙏

Finding Genius Podcast

@finding_genius

4 years

@bengurionu The Non-Coding RNA Puzzle: Let's Discusses New Class of RNA Molecules. Listen to @BarakRotblat here: Episode also available on @ApplePodcasts : #noncoding #RNA #ncRNA #gene #genetics #Findinggeniuspodcast

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Barak Rotblat

@BarakRotblat

6 years

🔥We identified lncRNA that is up regulated in tumors of patients with poor survival and my student, Gal Mazor, figured out🎆 it promotes resistance to chimo in #Glioblastoma stem cells. Great collaboration with @MarcRemke and @AGLeprivier and friends

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Barak Rotblat

@BarakRotblat

7 years

So happy. Got the Israel Cancer Association grant and they gave me x3 more $ then I asked for.

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Barak Rotblat

@BarakRotblat

2 years

The last class of the semester - The Cell 2🕺

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Barak Rotblat

@BarakRotblat

2 years

Should I just walk into the Prof's office?

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Barak Rotblat

@BarakRotblat

1 year

Some ppl think that because they understand statistics they understand everything. Michael obviously doesn't get courage

Michael Eisen

@mbeisen

1 year

The Onion speaks with more courage, insight and moral clarity than the leaders of every academic institution put together. I wish there were a @TheOnion university.

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Barak Rotblat

@BarakRotblat

1 year

@OdedRechavi Perhaps part of the prob is that we don't see science as a community's collective effort where each of us plays a role. The incentives, reward functions, and such are very individual-based

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Barak Rotblat

@BarakRotblat

2 years

Junior getting ready to help in the lab

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Barak Rotblat

@BarakRotblat

2 years

@RackMada זרם ליברטני-סוציאליסטי: ליברטני נגד חילונים וסוציאליסטי לטובת חרדים/מתנחלים

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Barak Rotblat

@BarakRotblat

3 years

single cell seq reveals that there are problems in the middle east

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Barak Rotblat

@BarakRotblat

2 years

How to convince your friend to join in writing a book chapter

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Barak Rotblat

@BarakRotblat

5 years

למה ביולוגיה? האיור של עדי ברוקס (אישתי) והסיפור שלי

"חוקרים פרטיים": איך חלבונים מחליטים מה לעשות?

כמו בממשלה, גם קבלת החלטות בתא אצלנו בגוף היא עניין רציני שיש לו השלכות. ההבדל בין תאים סרטניים לתאים בריאים, למשל, נעוץ בתהליכי בקרה וקבלת החלטות

www.ynet.co.il

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Barak Rotblat

@BarakRotblat

2 years

1/ 🔥New preprint- I remember when @shaipilo said to me that a chaperone interacting with a protein is like a bee and a flower🐝🌷- he will model it!

Ecological network analysis reveals cancer-dependent chaperone-client interaction structure and...

Cancer cells alter the expression levels of metabolic enzymes to fuel proliferation. The mitochondrion is a central hub of metabolic reprogramming, where multiple chaperons service hundreds of...

www.biorxiv.org

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Barak Rotblat

@BarakRotblat

5 years

Lab picnic

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Barak Rotblat

@BarakRotblat

5 years

A new compound killing tumor cells ONLY upon glucose starvation! Fun collaboration with @Akabayov_Lab @MDPIOpenAccess

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Barak Rotblat

@BarakRotblat

2 years

Co-culture

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Barak Rotblat

@BarakRotblat

2 years

Big lab takes all the funding

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Barak Rotblat

@BarakRotblat

2 years

"Petting a baby camel will make you happy"

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Barak Rotblat

@BarakRotblat

2 years

Me when students show me new data

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Barak Rotblat

@BarakRotblat

7 years

First experimental paper for the lab! We found that using puromycin to measure protein synthesis under starvation is problematic. We did a bunch of experiments to convince ourselves and our referees.

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Barak Rotblat

@BarakRotblat

3 years

Things you find when you finally cleanup the -80

Taylor McCoy 🦖

@TM9380

3 years

While somewhat distorted due to the preservation, looking down the Cleveland skull gives an excellent peak at binocular vision in Tyrannosaurus. #TyrannosaurTuesday #dinosaurs #paleontology

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Barak Rotblat

@BarakRotblat

1 year

I can't really concrete these days but I'll give it a go. Geut was my master student and now is the lab manager of @shaipilo an expert on network analysis in ecology. Geut did most of the work and I'm super proud of her. A lovely collaboration /

Nature Communications

@NatureComms

1 year

Galai et al. use ecological network analysis to find a hierarchical pattern whereby cancer type modulates chaperone-client interactions & simulations to identify structures affecting cancer-specific responses to chaperone loss. @shaipilo @BarakRotblat

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Barak Rotblat

@BarakRotblat

2 years

Really interesting poster🤘 #eacrCancerMetabolism

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Barak Rotblat

@BarakRotblat

3 years

Went for a little hike with the kids

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Barak Rotblat

@BarakRotblat

6 years

It was such fun to give a talk on evolution, wolves and 🐕 to my son's first grade class

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Barak Rotblat

@BarakRotblat

5 years

#physiologicalirrelevantconference A-WA rocked! What a day

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Barak Rotblat

@BarakRotblat

3 years

Mom donated one of her paintings to the @LsBgu and @zarivach , our chair, loved it

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Barak Rotblat

@BarakRotblat

2 years

With my man @Elkabetslab at our Department Day🥂 @LsBgu

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Barak Rotblat

@BarakRotblat

3 years

90% of the Goldfish answered that they drive better than average

Ronen Segev

@ronen_segev

3 years

I am excited to share a new study led by Shachar Givon & @MatanSamina w/ Ohad Ben Shahar: Goldfish can learn to navigate a small robotic vehicle on land. We trained goldfish to drive a wheeled platform that reacts to the fish’s movement ().

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Barak Rotblat

@BarakRotblat

5 years

Taking my bro @Elkabetslab for a drink cus his now Prof. Elkabets!

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Barak Rotblat

@BarakRotblat

10 months

פודקסט חדש של הקורס ביולוגיה ללא ביולוגים🎙️ פרופ" דבי טויבר @ToiberDebbie ואני שוחחנו עם ד"ר שי פילוסוף @shaipilo על איך משלבים אהבה לטיולים ותכנות. שי משתמש במדע של רשתות ועונה על שאלות באקולוגיה🐝🐸🌸 לד"ר בוזי רביד והאולפן הכייפי שלו🙏 @bengurionu

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Barak Rotblat

@BarakRotblat

10 months

My friends took me climbing at beitiful Timna last weekend 🧗🏽‍♀️ It was very physical and I haven't felt so good sice October 7th. Merry Christmas❄️🌲

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Barak Rotblat

@BarakRotblat

5 years

So proud! My first student, started as a master student now MD-PhD candidate, presenting at the joint IIS and ISCR meeting in Tel-Aviv. Thank you organizers 🤗 for giving students talking slots. It makes a huge difference Pic - Gal Mazor presenting

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Barak Rotblat

@BarakRotblat

5 years

Recelabrating @Elkabetslab professorship, @ToiberDebbie ERC, Shimon Bershtein and @Akabayov_Lab papers Love these ppl

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Barak Rotblat

@BarakRotblat

4 years

דבי @ToiberDebbie ואני מקליטים כל שבוע פודקסט עבור הקורס ביולוגיה ללא ביולוגים ובו אנו משוחחים עם מדעןנית על הקריירה, בחירת נושאי מחקר, השראה, רגעי אאורקה ואתגרים לאורך הדרך. שבוע שעבר שוחחנו עם עודד רכבי @OdedRechavi והיה כייף רב😎 האזנה נעימה

פרק 5: פרופ' עודד רכבי by ביולוגיה ללא-ביולוגים

פרופ' עודד רכבי מהי אפיגנטיקה? מה הסקיל הכי חשוב בשביל קריירה מדעית? מה הניסוי שעודד ביצע והכי התלהב ממנו אי פעם? מה העתיד של כנסים מדעיים? ומה האתגר הבא של המדע? הקשיבו ותדעו! מגישים: ד"ר דבי טויבר...

podcasters.spotify.com

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Barak Rotblat

@BarakRotblat

5 years

🔥New paper out 🔥 We identified a clinically relevant and functional #lncRNA in #medulloblastoma . It was beautiful to see ppl in the lab contributing towards the revision. Love working with friends - @MarcRemke @AGLeprivier @Elkabetslab .

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Barak Rotblat

@BarakRotblat

2 years

Hee we go #eacrCancerMetabolism

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Barak Rotblat

@BarakRotblat

4 years

"we developed an AI algorithm to wake up ppl falling asleep during the zoom meeting."

Rock Mada

@RackMada

4 years

צב האוזן האדומה מנסה לעורר את הנקבה בכדי להתרבות עמה, הזכר הוא הצב עם האצבעות הארוכות, וזהו חלק ממנהג החיזור אצל צבים אלו.

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Barak Rotblat

@BarakRotblat

5 years

Had a blast talking to kids in Dimona about Cancer

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Barak Rotblat

@BarakRotblat

2 years

@OdedRechavi Now in Beersheva

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Barak Rotblat

@BarakRotblat

2 years

So pleased Nahum Sonenberg will come to visit us @BenGurionUni . One of my science heroes! @SonenbergLab @LsBgu

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Barak Rotblat

@BarakRotblat

6 years

Happy to report that I joined @ivanoamelio at the Cell Death and Disease @cddpress Editorial crew. My job is to help you publish your beautiful science so feel free to @ me

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Barak Rotblat

@BarakRotblat

3 years

Radioactive biochem assay, Rsqr=1🤯 Calibration curve

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Barak Rotblat

@BarakRotblat

2 years

This is the hyper-capitalistic scientific system. The person from a top institute who first publishes the idea in a glam journal gets all the credit. Dosn't matter they got the idea from someone else. Ideas are the reason I do science

Oded Rechavi

@OdedRechavi

2 years

My main conclusion from yesterday (kind of sad in my opinion): A significant percentage of the scientific community doesn't think ideas are a real thing that should be credited and value ideas less than hard work* *based on hundreds of replies to our commentary

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Barak Rotblat

@BarakRotblat

2 years

Co-first

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Barak Rotblat

@BarakRotblat

4 years

This was last week. Went out for to celebrate @ToiberDebbie and Ramon Birnbaum getting a nice grant with friends from our department

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Barak Rotblat

@BarakRotblat

3 years

"If you want to succeed in this world my son, you got to publish in Nature"

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Barak Rotblat

@BarakRotblat

3 years

"But did he really leave a mark on the field?"

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Barak Rotblat

@BarakRotblat

3 years

Celebration @Elkabetslab paper at @jitcancer 🥳🥂 Coming soon

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Barak Rotblat

@BarakRotblat

3 years

@DrSalinasLab @thepostdoctoral Reviewing bad science is so much work

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Barak Rotblat

@BarakRotblat

2 years

@DDisatnik קצת נידה במרק לא הרגה אף אחד. אני בעד שמי שלא מוכן ללמוד מנשים שישאיר בישיבה. באיזו קלות מוכנים לזרוק את הערכים שלנו בשביל לספק מיזוגנים שיעשו מה בדיוק, טובה גדולה לאנשות שהם מוכנים לרכוש השכלה? רוצים לשאת בעולה של תורה, מעולה, תשארו בורים ועניים,אחיותינו לא ישלמו את המחיר

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Barak Rotblat

@BarakRotblat

6 years

New paper out! In vitro vs. in vivo. Priviously we found p73 regulates mRNA translation in culture. * But what's it doing in vivo? * We measured protein synthesis in brain slices of p73 KO and WT mice and found no difference.

Sustained protein synthesis and reduced eEF2K levels in TAp73-\- mice brain: a possible compensat...

The transcription factor p73 is a member of the p53 family, of which the transactivation domain containing isoform (TAp73) plays key roles in brain development and neuronal stem cells. TAp73 also f...

www.tandfonline.com

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Barak Rotblat

@BarakRotblat

3 years

@whereisdaz @CraigKellyMP True. I am just wondering, is there any proof he had nothing to do with those deaths?

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Barak Rotblat

@BarakRotblat

5 years

Hanging with my students in Crete *Gal and Hila are not on Twitter

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Barak Rotblat

@BarakRotblat

6 years

You think a transcription factor regulates only transcription? p73 (a brother of p53) also regulates #Translation . The project I developed with my friends at the @melino_G lab @MRC_TU is (finally) out.

TAp73 contributes to the oxidative stress response by regulating protein synthesis | PNAS

TAp73 is a transcription factor that plays key roles in brain development, aging, and cancer. At the cellular level, TAp73 is a critical homeostasi...

www.pnas.org

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Barak Rotblat

@BarakRotblat

2 years

The committee decided, only the chair can wear the special hat

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Barak Rotblat

@BarakRotblat

1 year

🔥Mitochondrial chaperones and drug resistance/sensitivity in cancer🔥 Our joint PhD student Mai, asked @Elkabetslab and I to do a bioinfo project because she wanted to learn how to code. She did it!

Gene Expression and Drug Sensitivity Analysis of Mitochondrial Chaperones Reveals That HSPD1 and...

Mitochondria—critical metabolic hubs in eukaryotic cells—are involved in a wide range of cellular functions, including differentiation, proliferation, and death. Mitochondria import most of their...

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Barak Rotblat

@BarakRotblat

6 years

My kids asked for the human body on the birthday cake. My wife came up with this one.

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Barak Rotblat

@BarakRotblat

3 years

"I'd rather have a good scientist with the broken English than the other way around" - SB

Shai Bel

@Mucus_Man

3 years

This is the problem. Not everyone is an English native speaker, not everyone had access to the same level of education as a child. Learning a new language at 30 is not the same than as a child. I'd rather have a good scientist with the broken English than the other way around

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Barak Rotblat

@BarakRotblat

3 years

Vacation